产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
CD3-zeta (6B10.2) Antibody
目录 :
sc-1239
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6B10.2
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 24
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 6c
Kim H, Mun Y, Lee K, Park Y, Park J, Park J, et al. T cell microvilli constitute immunological synaptosomes that carry messages to antigen-presenting cells. Nat Commun. 2018;9:3630 pubmed 出版商
  • 免疫印迹; 人类; 图 s7
Li L, Guo X, Shi X, Li C, Wu W, Yan C, et al. Ionic CD3-Lck interaction regulates the initiation of T-cell receptor signaling. Proc Natl Acad Sci U S A. 2017;114:E5891-E5899 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:4000; 图 3
Miyan M, Schmidt Mende J, Kiessling R, Poschke I, de Boniface J. Differential tumor infiltration by T-cells characterizes intrinsic molecular subtypes in breast cancer. J Transl Med. 2016;14:227 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1a
Moulton V, Gillooly A, Perl M, Markopoulou A, Tsokos G. Serine Arginine-Rich Splicing Factor 1 (SRSF1) Contributes to the Transcriptional Activation of CD3ζ in Human T Cells. PLoS ONE. 2015;10:e0131073 pubmed 出版商
  • 免疫组化; 人类
Fujisawa D, Kashiwakura J, Kita H, Kikukawa Y, Fujitani Y, Sasaki Sakamoto T, et al. Expression of Mas-related gene X2 on mast cells is upregulated in the skin of patients with severe chronic urticaria. J Allergy Clin Immunol. 2014;134:622-633.e9 pubmed 出版商
Suárez Fueyo A, Bradley S, Katsuyama T, Solomon S, Katsuyama E, Kyttaris V, et al. Downregulation of CD3ζ in NK Cells from Systemic Lupus Erythematosus Patients Confers a Proinflammatory Phenotype. J Immunol. 2018;200:3077-3086 pubmed 出版商
Wallis A, Wallace E, Hostager B, Yi Z, Houtman J, Bishop G. TRAF3 enhances TCR signaling by regulating the inhibitors Csk and PTPN22. Sci Rep. 2017;7:2081 pubmed 出版商
Krshnan L, Park S, Im W, Call M, Call M. A conserved ?? transmembrane interface forms the core of a compact T-cell receptor-CD3 structure within the membrane. Proc Natl Acad Sci U S A. 2016;113:E6649-E6658 pubmed
Wang E, Wang L, Tsai C, Bhoj V, Gershenson Z, Moon E, et al. Generation of Potent T-cell Immunotherapy for Cancer Using DAP12-Based, Multichain, Chimeric Immunoreceptors. Cancer Immunol Res. 2015;3:815-26 pubmed 出版商
Kongsbak M, von Essen M, Boding L, Levring T, Schjerling P, Lauritsen J, et al. Vitamin D up-regulates the vitamin D receptor by protecting it from proteasomal degradation in human CD4+ T cells. PLoS ONE. 2014;9:e96695 pubmed 出版商
Zha X, Chen S, Yang L, Shi L, Li B, Wu X, et al. Upregulated TCR? enhances interleukin-2 production in T-cells from patients with CML. DNA Cell Biol. 2012;31:1628-35 pubmed 出版商
Rovira Clavé X, Angulo Ibáñez M, Noguer O, Espel E, Reina M. Syndecan-2 can promote clearance of T-cell receptor/CD3 from the cell surface. Immunology. 2012;137:214-25 pubmed 出版商
Shuh M, Morse B, Heidecker G, Derse D. Association of SRC-related kinase Lyn with the interleukin-2 receptor and its role in maintaining constitutive phosphorylation of JAK/STAT in human T-cell leukemia virus type 1-transformed T cells. J Virol. 2011;85:4623-7 pubmed 出版商
Wang Y, Klumpp S, Amin H, Liang H, Li J, Estrov Z, et al. SSBP2 is an in vivo tumor suppressor and regulator of LDB1 stability. Oncogene. 2010;29:3044-53 pubmed 出版商
Methi T, Berge T, Torgersen K, Tasken K. Reduced Cbl phosphorylation and degradation of the zeta-chain of the T-cell receptor/CD3 complex in T cells with low Lck levels. Eur J Immunol. 2008;38:2557-63 pubmed 出版商
Montgomery J, Hensler H, Jacobson L, Jenkins F. Validation of a low cost computer-based method for quantification of immunohistochemistry-stained sections. Appl Immunohistochem Mol Morphol. 2008;16:400-4 pubmed 出版商
Methi T, Ngai J, Vang T, Torgersen K, Tasken K. Hypophosphorylated TCR/CD3zeta signals through a Grb2-SOS1-Ras pathway in Lck knockdown cells. Eur J Immunol. 2007;37:2539-48 pubmed
Guo S, Lin D, Li J, Liu R, Zhou C, Wang D, et al. Tumor-associated macrophages and CD3-zeta expression of tumor-infiltrating lymphocytes in human esophageal squamous-cell carcinoma. Dis Esophagus. 2007;20:107-16 pubmed
Rouquette Jazdanian A, Pelassy C, Breittmayer J, Aussel C. Full CD3/TCR activation through cholesterol-depleted lipid rafts. Cell Signal. 2007;19:1404-18 pubmed
Methi T, Ngai J, Mahic M, Amarzguioui M, Vang T, Tasken K. Short-interfering RNA-mediated Lck knockdown results in augmented downstream T cell responses. J Immunol. 2005;175:7398-406 pubmed
Myers M, Dragone L, Weiss A. Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation. J Cell Biol. 2005;170:285-94 pubmed
Torelli G, Guarini A, Maggio R, Alfieri C, Vitale A, Foa R. Expansion of natural killer cells with lytic activity against autologous blasts from adult and pediatric acute lymphoid leukemia patients in complete hematologic remission. Haematologica. 2005;90:785-92 pubmed
Crotta S, Stilla A, Wack A, D ANDREA A, Nuti S, D Oro U, et al. Inhibition of natural killer cells through engagement of CD81 by the major hepatitis C virus envelope protein. J Exp Med. 2002;195:35-41 pubmed
Sosinowski T, Pandey A, Dixit V, Weiss A. Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling. J Exp Med. 2000;191:463-74 pubmed
产品信息
产品名称 :
CD3-zeta (6B10.2) Antibody
基因名称 :
CD247
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-1239
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
CD3-zeta
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), FCM
表位 :
36-54(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。