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sc-126 AC
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500微克/毫升, 25% 老化
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人类, 小鼠
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免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片, ChIP-Seq, 其他, 免疫印迹基因敲除验证
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文章摘录数: 131
  • 免疫印迹; 人类; 图 ev2h
Zhao Y, Ding L, Wang D, Ye Z, He Y, Ma L, et al. EZH2 cooperates with gain-of-function p53 mutants to promote cancer growth and metastasis. EMBO J. 2019;38: pubmed 出版商
  • 免疫印迹; 人类; 图 3g
Liu B, Yi J, Yang X, Liu L, Lou X, Zhang Z, et al. MDM2-mediated degradation of WRN promotes cellular senescence in a p53-independent manner. Oncogene. 2019;38:2501-2515 pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Komori H, Goto Y, Kurayoshi K, Ozono E, Iwanaga R, Bradford A, et al. Differential requirement for dimerization partner DP between E2F-dependent activation of tumor suppressor and growth-related genes. Sci Rep. 2018;8:8438 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Giono L, Resnick Silverman L, Carvajal L, St Clair S, Manfredi J. Mdm2 promotes Cdc25C protein degradation and delays cell cycle progression through the G2/M phase. Oncogene. 2017;36:6762-6773 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 1f
  • 免疫印迹; 人类; 图 1f
Lee T, Pelletier J. Dependence of p53-deficient cells on the DHX9 DExH-box helicase. Oncotarget. 2017;8:30908-30921 pubmed 出版商
  • 免疫印迹; 人类; 图 s1b
Fumagalli A, Drost J, Suijkerbuijk S, van Boxtel R, de Ligt J, Offerhaus G, et al. Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids. Proc Natl Acad Sci U S A. 2017;114:E2357-E2364 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 s3
Liu T, Krysiak K, Shirai C, Kim S, Shao J, Ndonwi M, et al. Knockdown of HSPA9 induces TP53-dependent apoptosis in human hematopoietic progenitor cells. PLoS ONE. 2017;12:e0170470 pubmed 出版商
  • 免疫沉淀; 人类; 图 6D
  • 免疫印迹; 人类; 图 2D
Castellini L, Moon E, Razorenova O, Krieg A, von Eyben R, Giaccia A. KDM4B/JMJD2B is a p53 target gene that modulates the amplitude of p53 response after DNA damage. Nucleic Acids Res. 2017;45:3674-3692 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 4h-s
  • 免疫细胞化学; 人类; 图 4a-f
  • 免疫印迹; 人类; 图 2a
De Smet F, Saiz Rubio M, Hompes D, Naus E, De Baets G, Langenberg T, et al. Nuclear inclusion bodies of mutant and wild-type p53 in cancer: a hallmark of p53 inactivation and proteostasis remodelling by p53 aggregation. J Pathol. 2017;242:24-38 pubmed 出版商
  • 免疫沉淀; 人类; 图 2a
Qi D, Cobrinik D. MDM2 but not MDM4 promotes retinoblastoma cell proliferation through p53-independent regulation of MYCN translation. Oncogene. 2017;36:1760-1769 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Liu T, Xiong J, Yi S, Zhang H, Zhou S, Gu L, et al. FKBP12 enhances sensitivity to chemotherapy-induced cancer cell apoptosis by inhibiting MDM2. Oncogene. 2017;36:1678-1686 pubmed 出版商
  • 免疫组化; 人类; 1:500; 图 4a
  • 免疫印迹; 人类; 图 1b
D Brot A, Kurtz P, Regan E, Jakubowski B, Abrams J. A platform for interrogating cancer-associated p53 alleles. Oncogene. 2017;36:286-291 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Gotoh T, Kim J, Liu J, Vila Caballer M, Stauffer P, Tyson J, et al. Model-driven experimental approach reveals the complex regulatory distribution of p53 by the circadian factor Period 2. Proc Natl Acad Sci U S A. 2016;113:13516-13521 pubmed
  • 免疫印迹; 人类; 图 2c
Nonomiya Y, Noguchi K, Tanaka N, Kasagaki T, Katayama K, Sugimoto Y. Effect of AKT3 expression on MYC- and caspase-8-dependent apoptosis caused by polo-like kinase inhibitors in HCT 116 cells. Cancer Sci. 2016;107:1877-1887 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1e
Zhuang J, Kamp W, Li J, Liu C, Kang J, Wang P, et al. Forkhead Box O3A (FOXO3) and the Mitochondrial Disulfide Relay Carrier (CHCHD4) Regulate p53 Protein Nuclear Activity in Response to Exercise. J Biol Chem. 2016;291:24819-24827 pubmed
  • 免疫印迹; 人类; 图 5
Minemura H, Takagi K, Sato A, Takahashi H, Miki Y, Shibahara Y, et al. CITED2 in breast carcinoma as a potent prognostic predictor associated with proliferation, migration and chemoresistance. Cancer Sci. 2016;107:1898-1908 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Kozakai Y, Kamada R, Furuta J, Kiyota Y, Chuman Y, Sakaguchi K. PPM1D controls nucleolar formation by up-regulating phosphorylation of nucleophosmin. Sci Rep. 2016;6:33272 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1a
Tavana O, Li D, Dai C, Lopez G, Banerjee D, Kon N, et al. HAUSP deubiquitinates and stabilizes N-Myc in neuroblastoma. Nat Med. 2016;22:1180-1186 pubmed 出版商
  • 免疫印迹; 人类; 图 s10
Bauer M, Joerger A, Fersht A. 2-Sulfonylpyrimidines: Mild alkylating agents with anticancer activity toward p53-compromised cells. Proc Natl Acad Sci U S A. 2016;113:E5271-80 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Park J, Yang S, Park J, Ka S, Kim J, Kong Y, et al. Positive feedback regulation of p53 transactivity by DNA damage-induced ISG15 modification. Nat Commun. 2016;7:12513 pubmed 出版商
  • ChIP-Seq; 小鼠; 图 1a
Adriaens C, Standaert L, Barra J, Latil M, Verfaillie A, Kalev P, et al. p53 induces formation of NEAT1 lncRNA-containing paraspeckles that modulate replication stress response and chemosensitivity. Nat Med. 2016;22:861-8 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类; 图 1d
Itahana Y, Zhang J, Göke J, Vardy L, Han R, Iwamoto K, et al. Histone modifications and p53 binding poise the p21 promoter for activation in human embryonic stem cells. Sci Rep. 2016;6:28112 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 1
  • 免疫印迹; 人类; 图 1
  • 染色质免疫沉淀 ; 小鼠; 图 4
  • 免疫印迹; 小鼠; 图 4
Zhou X, Hao Q, Liao P, Luo S, Zhang M, Hu G, et al. Nerve growth factor receptor negates the tumor suppressor p53 as a feedback regulator. elife. 2016;5: pubmed 出版商
  • 免疫印迹; 人类; 图 s8
Chen S, FORRESTER W, Lahav G. Schedule-dependent interaction between anticancer treatments. Science. 2016;351:1204-8 pubmed 出版商
  • 流式细胞仪; 人类; 图 6f
  • 免疫印迹; 人类; 1:500; 图 1a
Frum R, Love I, Damle P, Mukhopadhyay N, Palit Deb S, Deb S, et al. Constitutive Activation of DNA Damage Checkpoint Signaling Contributes to Mutant p53 Accumulation via Modulation of p53 Ubiquitination. Mol Cancer Res. 2016;14:423-36 pubmed 出版商
  • 免疫印迹; 小鼠; 图 ev1f
  • 免疫印迹; 人类; 图 3a
Liu X, Tan Y, Zhang C, Zhang Y, Zhang L, Ren P, et al. NAT10 regulates p53 activation through acetylating p53 at K120 and ubiquitinating Mdm2. EMBO Rep. 2016;17:349-66 pubmed 出版商
  • 其他; 人类; 图 st1
Kanderová V, Kuzilkova D, Stuchly J, Vaskova M, Brdicka T, Fiser K, et al. High-resolution Antibody Array Analysis of Childhood Acute Leukemia Cells. Mol Cell Proteomics. 2016;15:1246-61 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Berges C, Chatterjee M, Topp M, Einsele H. Targeting polo-like kinase 1 suppresses essential functions of alloreactive T cells. Immunol Res. 2016;64:687-98 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Du C, Wu H, Leng R. UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation. Oncotarget. 2016;7:2823-36 pubmed 出版商
  • 免疫组化; 人类; 1:200; 表 4
Pages M, Lacroix L, Tauziède Espariat A, Castel D, Daudigeos Dubus E, Ridola V, et al. Papillary glioneuronal tumors: histological and molecular characteristics and diagnostic value of SLC44A1-PRKCA fusion. Acta Neuropathol Commun. 2015;3:85 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4d
Kanu N, Zhang T, Burrell R, Chakraborty A, Cronshaw J, DaCosta C, et al. RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress. Oncogene. 2016;35:4009-19 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Shatz M, Shats I, Menendez D, Resnick M. p53 amplifies Toll-like receptor 5 response in human primary and cancer cells through interaction with multiple signal transduction pathways. Oncotarget. 2015;6:16963-80 pubmed
  • 免疫印迹; 人类; 图 2b
Zhu J, Zhao C, Zhuang T, Jonsson P, Sinha I, Williams C, et al. RING finger protein 31 promotes p53 degradation in breast cancer cells. Oncogene. 2016;35:1955-64 pubmed 出版商
  • 免疫印迹; 人类
Neo S, Itahana Y, Alagu J, Kitagawa M, Guo A, Lee S, et al. TRIM28 Is an E3 Ligase for ARF-Mediated NPM1/B23 SUMOylation That Represses Centrosome Amplification. Mol Cell Biol. 2015;35:2851-63 pubmed 出版商
  • 免疫印迹; 人类; 图 s7f
Kloet D, Polderman P, Eijkelenboom A, Smits L, van Triest M, van den Berg M, et al. FOXO target gene CTDSP2 regulates cell cycle progression through Ras and p21(Cip1/Waf1). Biochem J. 2015;469:289-98 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250
Andries V, Vandepoele K, Staes K, Berx G, Bogaert P, Van Isterdael G, et al. NBPF1, a tumor suppressor candidate in neuroblastoma, exerts growth inhibitory effects by inducing a G1 cell cycle arrest. BMC Cancer. 2015;15:391 pubmed 出版商
  • 免疫印迹; 人类; 1:10000
Wright J, Atwan Z, Morris S, Leppard K. The Human Adenovirus Type 5 L4 Promoter Is Negatively Regulated by TFII-I and L4-33K. J Virol. 2015;89:7053-63 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Isogai T, van der Kammen R, Innocenti M. SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton. Sci Rep. 2015;5:9802 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Drost J, van Jaarsveld R, Ponsioen B, Zimberlin C, van Boxtel R, Buijs A, et al. Sequential cancer mutations in cultured human intestinal stem cells. Nature. 2015;521:43-7 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Seiki T, Nagasaka K, Kranjec C, Kawana K, Maeda D, Nakamura H, et al. HPV-16 impairs the subcellular distribution and levels of expression of protein phosphatase 1γ in cervical malignancy. BMC Cancer. 2015;15:230 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Stolz A, Ertych N, Bastians H. A phenotypic screen identifies microtubule plus end assembly regulators that can function in mitotic spindle orientation. Cell Cycle. 2015;14:827-37 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Butin Israeli V, Adam S, Jain N, Otte G, Neems D, Wiesmüller L, et al. Role of lamin b1 in chromatin instability. Mol Cell Biol. 2015;35:884-98 pubmed 出版商
  • 免疫印迹; 人类
Ghorbani A, Jeddi Tehrani M, Saidpour A, Safa M, Bayat A, Zand H. PI3K/AKT and Mdm2 activation are associated with inhibitory effect of cAMP increasing agents on DNA damage-induced cell death in human pre-B NALM-6 cells. Arch Biochem Biophys. 2015;566:58-66 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s1
Park J, Lee S, Yang S, Yoo H, Park J, Seong M, et al. Modification of DBC1 by SUMO2/3 is crucial for p53-mediated apoptosis in response to DNA damage. Nat Commun. 2014;5:5483 pubmed 出版商
  • 免疫印迹; 人类
Idogawa M, Ohashi T, Sugisaka J, Sasaki Y, Suzuki H, Tokino T. Array-based genome-wide RNAi screening to identify shRNAs that enhance p53-related apoptosis in human cancer cells. Oncotarget. 2014;5:7540-8 pubmed
  • 免疫印迹; 人类
Alpay K, Farshchian M, Tuomela J, Sandholm J, Aittokallio K, Siljamäki E, et al. Inhibition of c-Abl kinase activity renders cancer cells highly sensitive to mitoxantrone. PLoS ONE. 2014;9:e105526 pubmed 出版商
  • 免疫印迹; 人类
Li L, Wu P, Lee J, Li P, Hsieh W, Ho C, et al. Hinokitiol induces DNA damage and autophagy followed by cell cycle arrest and senescence in gefitinib-resistant lung adenocarcinoma cells. PLoS ONE. 2014;9:e104203 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Oi N, Yuan J, Malakhova M, Luo K, Ryu J, Zhang L, et al. Resveratrol induces apoptosis by directly targeting Ras-GTPase-activating protein SH3 domain-binding protein 1. Oncogene. 2015;34:2660-71 pubmed 出版商
  • 免疫印迹; 人类
Yamauchi T, Nishiyama M, Moroishi T, Yumimoto K, Nakayama K. MDM2 mediates nonproteolytic polyubiquitylation of the DEAD-Box RNA helicase DDX24. Mol Cell Biol. 2014;34:3321-40 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Luo X, Suzuki M, Ghandhi S, Amundson S, Boothman D. ATM regulates insulin-like growth factor 1-secretory clusterin (IGF-1-sCLU) expression that protects cells against senescence. PLoS ONE. 2014;9:e99983 pubmed 出版商
  • 免疫印迹; 小鼠
  • 免疫印迹; 人类
Mahadevan D, Morales C, Cooke L, Manziello A, Mount D, Persky D, et al. Alisertib added to rituximab and vincristine is synthetic lethal and potentially curative in mice with aggressive DLBCL co-overexpressing MYC and BCL2. PLoS ONE. 2014;9:e95184 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Gad H, Koolmeister T, Jemth A, Eshtad S, Jacques S, Ström C, et al. MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool. Nature. 2014;508:215-21 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Facciuto F, Bugnon Valdano M, Marziali F, Massimi P, Banks L, Cavatorta A, et al. Human papillomavirus (HPV)-18 E6 oncoprotein interferes with the epithelial cell polarity Par3 protein. Mol Oncol. 2014;8:533-43 pubmed 出版商
  • 免疫印迹; 人类
Meijer A, Kruyt F, van der Zee A, Hollema H, Le P, Ten Hoor K, et al. Nutlin-3 preferentially sensitises wild-type p53-expressing cancer cells to DR5-selective TRAIL over rhTRAIL. Br J Cancer. 2013;109:2685-95 pubmed 出版商
  • 免疫印迹; 人类
Gubanova E, Issaeva N, Gokturk C, Djureinovic T, Helleday T. SMG-1 suppresses CDK2 and tumor growth by regulating both the p53 and Cdc25A signaling pathways. Cell Cycle. 2013;12:3770-80 pubmed 出版商
  • 免疫印迹; 人类
Sy S, Jiang J, O W, Deng Y, Huen M. The ubiquitin specific protease USP34 promotes ubiquitin signaling at DNA double-strand breaks. Nucleic Acids Res. 2013;41:8572-80 pubmed 出版商
  • 免疫印迹; 小鼠
Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed 出版商
  • 免疫印迹; 人类
Ranaweera R, Yang X. Auto-ubiquitination of Mdm2 enhances its substrate ubiquitin ligase activity. J Biol Chem. 2013;288:18939-46 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Moreno A, Soleto I, García Sanz P, Moreno Bueno G, Palmero I. ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth. Oncogene. 2014;33:1945-53 pubmed 出版商
  • 免疫印迹; 人类
Kojima K, Kornblau S, Ruvolo V, Dilip A, Duvvuri S, Davis R, et al. Prognostic impact and targeting of CRM1 in acute myeloid leukemia. Blood. 2013;121:4166-74 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Andrews P, He Z, Tzenov Y, Popadiuk C, Kao K. Evidence of a novel role for Pygopus in rRNA transcription. Biochem J. 2013;453:61-70 pubmed 出版商
  • 免疫印迹; 人类
Jullien L, Mestre M, Roux P, Gire V. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Nucleic Acids Res. 2013;41:900-11 pubmed 出版商
  • 免疫印迹; 人类
Li X, Wu L, Corsa C, Kunkel S, Dou Y. Two mammalian MOF complexes regulate transcription activation by distinct mechanisms. Mol Cell. 2009;36:290-301 pubmed 出版商
  • 免疫印迹; 人类
Wolff S, Erster S, Palacios G, Moll U. p53's mitochondrial translocation and MOMP action is independent of Puma and Bax and severely disrupts mitochondrial membrane integrity. Cell Res. 2008;18:733-44 pubmed 出版商
  • 免疫印迹; 人类
Sakasai R, Tibbetts R. RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage. J Biol Chem. 2008;283:13549-55 pubmed 出版商
Román Rosales A, Garcia Villa E, Herrera L, Gariglio P, Diaz Chavez J. Mutant p53 gain of function induces HER2 over-expression in cancer cells. BMC Cancer. 2018;18:709 pubmed 出版商
Liao P, Zeng S, Zhou X, Chen T, Zhou F, Cao B, et al. Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding. Mol Cell. 2017;68:1134-1146.e6 pubmed 出版商
Parvathaneni S, Lu X, Chaudhary R, Lal A, Madhusudan S, Sharma S. RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner. Oncotarget. 2017;8:75924-75942 pubmed 出版商
Thaler S, Schmidt M, Roβwag S, Thiede G, Schad A, Sleeman J. Proteasome inhibitors prevent bi-directional HER2/estrogen-receptor cross-talk leading to cell death in endocrine and lapatinib-resistant HER2+/ER+ breast cancer cells. Oncotarget. 2017;8:72281-72301 pubmed 出版商
Pacini L, Ceraolo M, Venuti A, Melita G, Hasan U, Accardi R, et al. UV Radiation Activates Toll-Like Receptor 9 Expression in Primary Human Keratinocytes, an Event Inhibited by Human Papillomavirus 38 E6 and E7 Oncoproteins. J Virol. 2017;91: pubmed 出版商
Ghosh S, Salot S, Sengupta S, Navalkar A, Ghosh D, Jacob R, et al. p53 amyloid formation leading to its loss of function: implications in cancer pathogenesis. Cell Death Differ. 2017;24:1784-1798 pubmed 出版商
Al Khalaf H, Amir M, Al Mohanna F, Tulbah A, Al Sayed A, Aboussekhra A. Obesity and p16INK4A Downregulation Activate Breast Adipocytes and Promote Their Protumorigenicity. Mol Cell Biol. 2017;37: pubmed 出版商
Marmisolle I, Martínez J, Liu J, Mastrogiovanni M, Fergusson M, Rovira I, et al. Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation. Arch Biochem Biophys. 2017;613:12-22 pubmed 出版商
Ota A, Nakao H, Sawada Y, Karnan S, Wahiduzzaman M, Inoue T, et al. ?40p53? suppresses tumor cell proliferation and induces cellular senescence in hepatocellular carcinoma cells. J Cell Sci. 2017;130:614-625 pubmed 出版商
Sokolova M, Turunen M, Mortusewicz O, Kivioja T, Herr P, Vähärautio A, et al. Genome-wide screen of cell-cycle regulators in normal and tumor cells identifies a differential response to nucleosome depletion. Cell Cycle. 2017;16:189-199 pubmed 出版商
Ohashi T, Komatsu S, Ichikawa D, Miyamae M, Okajima W, Imamura T, et al. Overexpression of PBK/TOPK relates to tumour malignant potential and poor outcome of gastric carcinoma. Br J Cancer. 2017;116:218-226 pubmed 出版商
Tran T, Lowman X, Reid M, Mendez Dorantes C, Pan M, Yang Y, et al. Tumor-associated mutant p53 promotes cancer cell survival upon glutamine deprivation through p21 induction. Oncogene. 2017;36:1991-2001 pubmed 出版商
Gong L, Pan X, Chen H, Rao L, Zeng Y, Hang H, et al. p53 isoform Δ133p53 promotes efficiency of induced pluripotent stem cells and ensures genomic integrity during reprogramming. Sci Rep. 2016;6:37281 pubmed 出版商
Alfano L, Costa C, Caporaso A, Antonini D, Giordano A, Pentimalli F. HUR protects NONO from degradation by mir320, which is induced by p53 upon UV irradiation. Oncotarget. 2016;7:78127-78139 pubmed 出版商
Moureau S, Luessing J, Harte E, Voisin M, Lowndes N. A role for the p53 tumour suppressor in regulating the balance between homologous recombination and non-homologous end joining. Open Biol. 2016;6: pubmed
Yang C, Zhou Q, Li M, Tong X, Sun J, Qing Y, et al. Upregulation of CYP2S1 by oxaliplatin is associated with p53 status in colorectal cancer cell lines. Sci Rep. 2016;6:33078 pubmed 出版商
Monteith J, Mellert H, Sammons M, Kuswanto L, Sykes S, Resnick Silverman L, et al. A rare DNA contact mutation in cancer confers p53 gain-of-function and tumor cell survival via TNFAIP8 induction. Mol Oncol. 2016;10:1207-20 pubmed 出版商
Hong A, Tseng Y, Cowley G, Jonas O, Cheah J, Kynnap B, et al. Integrated genetic and pharmacologic interrogation of rare cancers. Nat Commun. 2016;7:11987 pubmed 出版商
Aggarwal M, Saxena R, Sinclair E, Fu Y, Jacobs A, Dyba M, et al. Reactivation of mutant p53 by a dietary-related compound phenethyl isothiocyanate inhibits tumor growth. Cell Death Differ. 2016;23:1615-27 pubmed 出版商
López Mateo I, Arruabarrena Aristorena A, Artaza Irigaray C, López J, Calvo E, Belandia B. HEY1 functions are regulated by its phosphorylation at Ser-68. Biosci Rep. 2016;36: pubmed 出版商
Shin M, He Y, Marrogi E, Piperdi S, Ren L, Khanna C, et al. A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells. PLoS Genet. 2016;12:e1005884 pubmed 出版商
Swetzig W, Wang J, Das G. Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer. Oncotarget. 2016;7:16049-69 pubmed 出版商
Talarico C, Dattilo V, D Antona L, Barone A, Amodio N, Belviso S, et al. SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells. Oncotarget. 2016;7:15868-84 pubmed 出版商
Iyer S, Parrales A, Begani P, Narkar A, Adhikari A, Martinez L, et al. Allele-specific silencing of mutant p53 attenuates dominant-negative and gain-of-function activities. Oncotarget. 2016;7:5401-15 pubmed 出版商
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