产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
alpha突触核蛋白(211)抗体
目录 :
sc-12767
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
211
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 23
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 3
Dansithong W, Paul S, Scoles D, Pulst S, Huynh D. Generation of SNCA Cell Models Using Zinc Finger Nuclease (ZFN) Technology for Efficient High-Throughput Drug Screening. PLoS ONE. 2015;10:e0136930 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Mbefo M, Fares M, Paleologou K, Oueslati A, Yin G, Tenreiro S, et al. Parkinson disease mutant E46K enhances α-synuclein phosphorylation in mammalian cell lines, in yeast, and in vivo. J Biol Chem. 2015;290:9412-27 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:2000
Aldrin Kirk P, Davidsson M, Holmqvist S, Li J, Bjorklund T. Novel AAV-based rat model of forebrain synucleinopathy shows extensive pathologies and progressive loss of cholinergic interneurons. PLoS ONE. 2014;9:e100869 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Dettmer U, Newman A, Luth E, Bartels T, Selkoe D. In vivo cross-linking reveals principally oligomeric forms of ?-synuclein and ?-synuclein in neurons and non-neural cells. J Biol Chem. 2013;288:6371-85 pubmed 出版商
  • 免疫印迹; 人类
Ko L, Ko H, Lin W, Kulathingal J, Yen S. Aggregates assembled from overexpression of wild-type alpha-synuclein are not toxic to human neuronal cells. J Neuropathol Exp Neurol. 2008;67:1084-96 pubmed 出版商
Pérez Rodríguez D, Kalyva M, Leija Salazar M, Lashley T, Tarabichi M, Chelban V, et al. Investigation of somatic CNVs in brains of synucleinopathy cases using targeted SNCA analysis and single cell sequencing. Acta Neuropathol Commun. 2019;7:219 pubmed 出版商
Chumarina M, Russ K, Azevedo C, Heuer A, Pihl M, Collin A, et al. Cellular alterations identified in pluripotent stem cell-derived midbrain spheroids generated from a female patient with progressive external ophthalmoplegia and parkinsonism who carries a novel variation (p.Q811R) in the POLG1 gene. Acta Neuropathol Commun. 2019;7:208 pubmed 出版商
Wu J, Ardah M, Haikal C, Svanbergsson A, Diepenbroek M, Vaikath N, et al. Dihydromyricetin and Salvianolic acid B inhibit alpha-synuclein aggregation and enhance chaperone-mediated autophagy. Transl Neurodegener. 2019;8:18 pubmed 出版商
Hu D, Sun X, Liao X, Zhang X, Zarabi S, Schimmer A, et al. Alpha-synuclein suppresses mitochondrial protease ClpP to trigger mitochondrial oxidative damage and neurotoxicity. Acta Neuropathol. 2019;137:939-960 pubmed 出版商
Chen Q, Haikal C, Li W, Li M, Wang Z, Li J. Age-dependent alpha-synuclein accumulation and aggregation in the colon of a transgenic mouse model of Parkinson's disease. Transl Neurodegener. 2018;7:13 pubmed 出版商
Jan A, Jansonius B, Delaidelli A, Bhanshali F, An Y, Ferreira N, et al. Activity of translation regulator eukaryotic elongation factor-2 kinase is increased in Parkinson disease brain and its inhibition reduces alpha synuclein toxicity. Acta Neuropathol Commun. 2018;6:54 pubmed 出版商
Patel D, Xu C, Nagarajan S, Liu Z, Hemphill W, Shi R, et al. Alpha-synuclein inhibits Snx3-retromer-mediated retrograde recycling of iron transporters in S. cerevisiae and C. elegans models of Parkinson's disease. Hum Mol Genet. 2018;27:1514-1532 pubmed 出版商
Zunke F, Moise A, Belur N, Gelyana E, Stojkovska I, Dzaferbegovic H, et al. Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide. Neuron. 2018;97:92-107.e10 pubmed 出版商
Filippini A, Bonini D, Lacoux C, Pacini L, Zingariello M, Sancillo L, et al. Absence of the Fragile X Mental Retardation Protein results in defects of RNA editing of neuronal mRNAs in mouse. RNA Biol. 2017;14:1580-1591 pubmed 出版商
de Oliveira R, Vicente Miranda H, Francelle L, Pinho R, Szego E, Martinho R, et al. The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson disease. PLoS Biol. 2017;15:e2000374 pubmed 出版商
Yuan J, Ren J, Wang Y, He X, Zhao Y. Acteoside Binds to Caspase-3 and Exerts Neuroprotection in the Rotenone Rat Model of Parkinson's Disease. PLoS ONE. 2016;11:e0162696 pubmed 出版商
Nisar R, Hanson P, He L, Taylor R, Blain P, Morris C. Diquat causes caspase-independent cell death in SH-SY5Y cells by production of ROS independently of mitochondria. Arch Toxicol. 2015;89:1811-25 pubmed 出版商
Cali T, Ottolini D, Negro A, Brini M. ?-Synuclein controls mitochondrial calcium homeostasis by enhancing endoplasmic reticulum-mitochondria interactions. J Biol Chem. 2012;287:17914-29 pubmed 出版商
Ha Y, Liew H, Park H, Kim K, Suh Y, Churchill D. Interplay of salicylaldehyde, lysine, and M2+ ions on ?-synuclein aggregation: cancellation of aggregation effects and determination of salicylaldehyde neurotoxicity. Neurosci Res. 2011;71:168-77 pubmed 出版商
Jin H, Kanthasamy A, Ghosh A, Yang Y, Anantharam V, Kanthasamy A. ?-Synuclein negatively regulates protein kinase C? expression to suppress apoptosis in dopaminergic neurons by reducing p300 histone acetyltransferase activity. J Neurosci. 2011;31:2035-51 pubmed 出版商
Sakurai M, Kawamura T, Nishimura H, Suzuki H, Tezuka F, Abe K. Induction of Parkinson disease-related proteins in motor neurons after transient spinal cord ischemia in rabbits. J Cereb Blood Flow Metab. 2009;29:752-8 pubmed 出版商
Vogiatzi T, Xilouri M, Vekrellis K, Stefanis L. Wild type alpha-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells. J Biol Chem. 2008;283:23542-56 pubmed 出版商
Fornai F, Schlüter O, Lenzi P, Gesi M, Ruffoli R, Ferrucci M, et al. Parkinson-like syndrome induced by continuous MPTP infusion: convergent roles of the ubiquitin-proteasome system and alpha-synuclein. Proc Natl Acad Sci U S A. 2005;102:3413-8 pubmed
产品信息
产品名称 :
alpha突触核蛋白(211)抗体
基因名称 :
SNCA
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-12767
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
alpha突触核蛋白
反应物种 :
人类
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P)
表位 :
121-125(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。