产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
HIF-1alpha(28b)抗体
目录 :
sc-13515
规格 :
200微克/毫升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
28b
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 38
出版应用/物种/样本/稀释参考文献
  • 染色质免疫沉淀 ; 人类; 图 10e
Du J, Yu Q, Liu Y, Du S, Huang L, Xu D, et al. A novel role of kallikrein-related peptidase 8 in the pathogenesis of diabetic cardiac fibrosis. Theranostics. 2021;11:4207-4231 pubmed 出版商
  • 免疫印迹; 人类; 1:300; 图 6a
Potilinski M, Ortiz G, Salica J, Lopez E, Fernández Acquier M, Chuluyan E, et al. Elucidating the mechanism of action of alpha-1-antitrypsin using retinal pigment epithelium cells exposed to high glucose. Potential use in diabetic retinopathy. PLoS ONE. 2020;15:e0228895 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 4e
Tang H, Feng H, Wang M, Zhu Q, Liu Y, Jiang Y. In vivo longitudinal and multimodal imaging of hypoxia-inducible factor 1α and angiogenesis in breast cancer. Chin Med J (Engl). 2020;133:205-211 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 5a
  • 免疫印迹; 小鼠; 图 4g
Jassim A, Inman D. Evidence of Hypoxic Glial Cells in a Model of Ocular Hypertension. Invest Ophthalmol Vis Sci. 2019;60:1-15 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 2a
Badowska Kozakiewicz A, Sobol M, Patera J. Expression of multidrug resistance protein P-glycoprotein in correlation with markers of hypoxia (HIF-1?, EPO, EPO-R) in invasive breast cancer with metastasis to lymph nodes. Arch Med Sci. 2017;13:1303-1314 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Li S, Liu H, Tang S, Li X, Wang X. MicroRNA-150 regulates glycolysis by targeting von Hippel-Lindau in glioma cells. Am J Transl Res. 2017;9:1058-1066 pubmed
  • 免疫印迹; 人类; 1:500; 图 3A
Guo Q, He J, Shen F, Zhang W, Yang X, Zhang C, et al. TCN, an AKT inhibitor, exhibits potent antitumor activity and enhances radiosensitivity in hypoxic esophageal squamous cell carcinoma in vitro and in vivo. Oncol Lett. 2017;13:949-954 pubmed 出版商
  • 免疫组化; 人类; 图 1e
Oh E, Kim J, Kim J, Kim S, Lee J, Hong S, et al. NQO1 inhibits proteasome-mediated degradation of HIF-1α. Nat Commun. 2016;7:13593 pubmed 出版商
  • 免疫沉淀; 人类; 1:200; 图 2f
  • 免疫印迹; 人类; 1:1000; 图 2f
Lin A, Li C, Xing Z, Hu Q, Liang K, Han L, et al. The LINK-A lncRNA activates normoxic HIF1? signalling in triple-negative breast cancer. Nat Cell Biol. 2016;18:213-24 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 1
Shen G, Ning N, Zhao X, Liu X, Wang G, Wang T, et al. Adipose differentiation-related protein is not involved in hypoxia inducible factor-1-induced lipid accumulation under hypoxia. Mol Med Rep. 2015;12:8055-61 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4
Rodríguez C, Reidel S, Bal de Kier Joffé E, Jasnis M, Fiszman G. Autophagy Protects from Trastuzumab-Induced Cytotoxicity in HER2 Overexpressing Breast Tumor Spheroids. PLoS ONE. 2015;10:e0137920 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 1
  • 免疫印迹; 人类; 1:1000; 图 1
Li X, Yang X, Biskup E, Zhou J, Li H, Wu Y, et al. Co-expression of CXCL8 and HIF-1α is associated with metastasis and poor prognosis in hepatocellular carcinoma. Oncotarget. 2015;6:22880-9 pubmed
  • 免疫组化-石蜡切片; 人类; 图 4
  • 免疫印迹; 人类; 图 3
Zhang Y, Fan N, Yang J. Expression and clinical significance of hypoxia-inducible factor 1?, Snail and E-cadherin in human ovarian cancer cell lines. Mol Med Rep. 2015;12:3393-3399 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 4
  • 免疫印迹; 人类; 图 4
Basu S, Majumder S, Bhowal A, Ghosh A, Naskar S, Nandy S, et al. A study of molecular signals deregulating mismatch repair genes in prostate cancer compared to benign prostatic hyperplasia. PLoS ONE. 2015;10:e0125560 pubmed 出版商
  • EMSA; 人类; 1 ug
Schaffner C, Mwinyi J, Gai Z, Thasler W, Eloranta J, Kullak Ublick G. The organic solute transporters alpha and beta are induced by hypoxia in human hepatocytes. Liver Int. 2015;35:1152-61 pubmed 出版商
Qiu H, Chen F, Chen M. MicroRNA-138 negatively regulates the hypoxia-inducible factor 1α to suppress melanoma growth and metastasis. Biol Open. 2019;8: pubmed 出版商
You Z, Yu M, Zhang Y, Shi K. Progranulin protects the mouse retina under hypoxic conditions via inhibition of the Toll‑like receptor‑4‑NADPH oxidase 4 signaling pathway. Mol Med Rep. 2019;19:382-390 pubmed 出版商
Ji W, Wang L, He S, Yan L, Li T, Wang J, et al. Effects of acute hypoxia exposure with different durations on activation of Nrf2-ARE pathway in mouse skeletal muscle. PLoS ONE. 2018;13:e0208474 pubmed 出版商
Kondratskyi A, Kondratska K, Vanden Abeele F, Gordienko D, Dubois C, Toillon R, et al. Ferroquine, the next generation antimalarial drug, has antitumor activity. Sci Rep. 2017;7:15896 pubmed 出版商
Zhang Y, Wang T, Wei J, He J, Wang T, Liu Y, et al. What's the remedy for the distal necrosis of DIEP flap, better venous drain or more arterial supply?. PLoS ONE. 2017;12:e0171651 pubmed 出版商
Xu W, Zhou W, Cheng M, Wang J, Liu Z, He S, et al. Hypoxia activates Wnt/β-catenin signaling by regulating the expression of BCL9 in human hepatocellular carcinoma. Sci Rep. 2017;7:40446 pubmed 出版商
Li S, Shao J, Zhou Y, Friis T, Yao J, Shi B, et al. The impact of Wnt signalling and hypoxia on osteogenic and cementogenic differentiation in human periodontal ligament cells. Mol Med Rep. 2016;14:4975-4982 pubmed 出版商
Gao C, Li S, Zhao T, Chen J, Ren H, Zhang H, et al. SCF, regulated by HIF-1α, promotes pancreatic ductal adenocarcinoma cell progression. PLoS ONE. 2015;10:e0121338 pubmed 出版商
Wang B, Ding Y, Fan P, Wang B, Xu J, Wang W. Expression and significance of MMP2 and HIF-1? in hepatocellular carcinoma. Oncol Lett. 2014;8:539-546 pubmed
Talaei F, Van Praag V, Shishavan M, Landheer S, Buikema H, Henning R. Increased protein aggregation in Zucker diabetic fatty rat brain: identification of key mechanistic targets and the therapeutic application of hydrogen sulfide. BMC Cell Biol. 2014;15:1 pubmed 出版商
Li F, Lu Y, Ding M, Napierala D, Abbassi S, Chen Y, et al. Runx2 contributes to murine Col10a1 gene regulation through direct interaction with its cis-enhancer. J Bone Miner Res. 2011;26:2899-910 pubmed 出版商
Heeg S, Hirt N, Queisser A, Schmieg H, Thaler M, Kunert H, et al. EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis. Cancer Sci. 2011;102:351-60 pubmed 出版商
Wang W, Reiser Erkan C, Michalski C, Raggi M, Quan L, Yupei Z, et al. Hypoxia inducible BHLHB2 is a novel and independent prognostic marker in pancreatic ductal adenocarcinoma. Biochem Biophys Res Commun. 2010;401:422-8 pubmed 出版商
Yu R, Ng P, Tan T, Chu D, Wu R, Kong R. Enhancement of hypoxia-induced gene expression in fish liver by the aryl hydrocarbon receptor (AhR) ligand, benzo[a]pyrene (BaP). Aquat Toxicol. 2008;90:235-42 pubmed 出版商
Okami N, Kawamata T, Yamamoto G, Okada Y, Hori T, Tachikawa T. Laser microdissection-based analysis of hypoxia- and thioredoxin-related genes in human stable carotid plaques. Cardiovasc Pathol. 2009;18:294-300 pubmed 出版商
Pisano C, Zuco V, De Cesare M, Benedetti V, Vesci L, Foderà R, et al. Intracellular accumulation and DNA damage persistence as determinants of human squamous cell carcinoma hypersensitivity to the novel camptothecin ST1968. Eur J Cancer. 2008;44:1332-40 pubmed 出版商
Tal R, Shaish A, Bangio L, Peled M, Breitbart E, Harats D. Activation of C-transactivation domain is essential for optimal HIF-1 alpha-mediated transcriptional and angiogenic effects. Microvasc Res. 2008;76:1-6 pubmed 出版商
Han Z, Ren H, Zhao H, Chi Y, Chen K, Zhou B, et al. Hypoxia-inducible factor (HIF)-1 alpha directly enhances the transcriptional activity of stem cell factor (SCF) in response to hypoxia and epidermal growth factor (EGF). Carcinogenesis. 2008;29:1853-61 pubmed 出版商
Shi L, Huang J, Han B. Hypoxia inducible factor-1alpha mediates protective effects of ischemic preconditioning on ECV-304 endothelial cells. World J Gastroenterol. 2007;13:2369-73 pubmed
Ioachim E, Michael M, Salmas M, Michael M, Stavropoulos N, Malamou Mitsi V. Hypoxia-inducible factors HIF-1alpha and HIF-2alpha expression in bladder cancer and their associations with other angiogenesis-related proteins. Urol Int. 2006;77:255-63 pubmed
Yoo Y, Kong G, Lee M. Metastasis-associated protein 1 enhances stability of hypoxia-inducible factor-1alpha protein by recruiting histone deacetylase 1. EMBO J. 2006;25:1231-41 pubmed
Anderson C, Hoare S, Ashcroft M, Bilsland A, Keith W. Hypoxic regulation of telomerase gene expression by transcriptional and post-transcriptional mechanisms. Oncogene. 2006;25:61-9 pubmed
Kyzas P, Stefanou D, Batistatou A, Agnantis N. Hypoxia-induced tumor angiogenic pathway in head and neck cancer: an in vivo study. Cancer Lett. 2005;225:297-304 pubmed
产品信息
产品名称 :
HIF-1alpha(28b)抗体
基因名称 :
缺氧诱导因子1A
规格 :
200微克/毫升
目录号 :
sc-13515
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
HIF-1alpha
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P)
表位 :
329-530(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。