产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
ERK 1/2(MK1)抗体
目录 :
sc-135900
规格 :
50微克/0.5毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MK1
反应物种 :
人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀
更多信息或购买 :
文章摘录数: 69
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Li R, Sahu S, Schachner M. Phenelzine, a small organic compound mimicking the functions of cell adhesion molecule L1, promotes functional recovery after mouse spinal cord injury. Restor Neurol Neurosci. 2018;36:469-483 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1a
Hegedüs L, Garay T, Molnar E, Varga K, Bilecz A, Torok S, et al. The plasma membrane Ca2+ pump PMCA4b inhibits the migratory and metastatic activity of BRAF mutant melanoma cells. Int J Cancer. 2017;140:2758-2770 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
Li S, Yang B, Teguh D, Zhou L, Xu J, Rong L. Amyloid ? Peptide Enhances RANKL-Induced Osteoclast Activation through NF-?B, ERK, and Calcium Oscillation Signaling. Int J Mol Sci. 2016;17: pubmed
  • 免疫印迹; 人类; 1:1000; 图 2
Jiang Q, Chen S, Hu C, Huang P, Shen H, Zhao W. Neuregulin-1 (Nrg1) signaling has a preventive role and is altered in the frontal cortex under the pathological conditions of Alzheimer's disease. Mol Med Rep. 2016;14:2614-24 pubmed 出版商
  • 免疫印迹; 人类; 图 6b
Madureira P, Bharadwaj A, Bydoun M, Garant K, O Connell P, Lee P, et al. Cell surface protease activation during RAS transformation: Critical role of the plasminogen receptor, S100A10. Oncotarget. 2016;7:47720-47737 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 6A
Maugeri G, D Amico A, Reitano R, Magro G, Cavallaro S, Salomone S, et al. PACAP and VIP Inhibit the Invasiveness of Glioblastoma Cells Exposed to Hypoxia through the Regulation of HIFs and EGFR Expression. Front Pharmacol. 2016;7:139 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s4
Wang J, Farris A, Xu K, Wang P, Zhang X, Duong D, et al. GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis. Nat Commun. 2016;7:11795 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4
Yang Z, Jiang Q, Chen S, Hu C, Shen H, Huang P, et al. Differential changes in Neuregulin-1 signaling in major brain regions in a lipopolysaccharide-induced neuroinflammation mouse model. Mol Med Rep. 2016;14:790-6 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 3
Maselli A, Capoccia S, Pugliese P, Raggi C, Cirulli F, Fabi A, et al. Autoantibodies specific to estrogen receptor alpha act as estrogen agonists and their levels correlate with breast cancer cell proliferation. Oncoimmunology. 2016;5:e1074375 pubmed
  • 免疫印迹; 人类; 1:200; 图 5
Maugeri G, D Amico A, Rasà D, Reitano R, Saccone S, Federico C, et al. Expression profile of Wilms Tumor 1 (WT1) isoforms in undifferentiated and all-trans retinoic acid differentiated neuroblastoma cells. Genes Cancer. 2016;7:47-58 pubmed
  • 免疫印迹; 小鼠; 1:1000; 图 5
Liu L, Zhu J, Zhou L, Wan L. RACK1 promotes maintenance of morphine-associated memory via activation of an ERK-CREB dependent pathway in hippocampus. Sci Rep. 2016;6:20183 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Quintero Barceinas R, García Regalado A, Aréchaga Ocampo E, Villegas Sepúlveda N, González De la Rosa C. All-Trans Retinoic Acid Induces Proliferation, Survival, and Migration in A549 Lung Cancer Cells by Activating the ERK Signaling Pathway through a Transcription-Independent Mechanism. Biomed Res Int. 2015;2015:404368 pubmed 出版商
  • 免疫印迹; 人类; 1:8000; 图 7
Zhou X, Tao Y, Liang C, Zhang Y, Li H, Chen Q. BMP3 Alone and Together with TGF-β Promote the Differentiation of Human Mesenchymal Stem Cells into a Nucleus Pulposus-Like Phenotype. Int J Mol Sci. 2015;16:20344-59 pubmed 出版商
  • 免疫印迹; 小鼠
Choi J, Kim J, Kim T, Park J, Lee J, Kim H, et al. TRH and TRH receptor system in the basolateral amygdala mediate stress-induced depression-like behaviors. Neuropharmacology. 2015;97:346-56 pubmed 出版商
  • 免疫印迹; 人类; 图 4d
Chen M, Yen C, Cheng C, Wu R, Huang S, Yu C, et al. Identification of SPHK1 as a therapeutic target and marker of poor prognosis in cholangiocarcinoma. Oncotarget. 2015;6:23594-608 pubmed
  • 免疫印迹; 人类
Faggi F, Codenotti S, Poliani P, Cominelli M, Chiarelli N, Colombi M, et al. MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line. PLoS ONE. 2015;10:e0130287 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 6
Korotkevych N, Labyntsev A, Kolybo D, Komisarenko S. The Soluble Heparin-Binding EGF-Like Growth Factor Stimulates EGF Receptor Trafficking to the Nucleus. PLoS ONE. 2015;10:e0127887 pubmed 出版商
  • 免疫印迹; 小鼠
Bargut T, Mandarim de Lacerda C, Aguila M. A high-fish-oil diet prevents adiposity and modulates white adipose tissue inflammation pathways in mice. J Nutr Biochem. 2015;26:960-9 pubmed 出版商
  • 免疫印迹; 人类
Wang B, Wu S, Tang S, Lai C, Ou C, Wu M, et al. Benzo[a]pyrene-induced cell cycle progression occurs via ERK-induced Chk1 pathway activation in human lung cancer cells. Mutat Res. 2015;773:1-8 pubmed 出版商
  • 免疫印迹; 人类
Fouladi F, Jehn L, Metzelder S, Hub F, Henkenius K, Burchert A, et al. Sorafenib induces paradoxical phosphorylation of the extracellular signal-regulated kinase pathway in acute myeloid leukemia cells lacking FLT3-ITD mutation. Leuk Lymphoma. 2015;56:2690-8 pubmed 出版商
  • 免疫印迹; 大鼠; 1:200
Castorina A, Waschek J, Marzagalli R, Cardile V, Drago F. PACAP interacts with PAC1 receptors to induce tissue plasminogen activator (tPA) expression and activity in schwann cell-like cultures. PLoS ONE. 2015;10:e0117799 pubmed 出版商
  • 免疫印迹; 大鼠; 1:200
Passos E, Pereira C, Gonçalves I, Rocha Rodrigues S, Silva N, Guimarães J, et al. Role of physical exercise on hepatic insulin, glucocorticoid and inflammatory signaling pathways in an animal model of non-alcoholic steatohepatitis. Life Sci. 2015;123:51-60 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3
Xu T, Pan Z, Dong M, Yu C, Niu Y. Ferulic acid suppresses activation of hepatic stellate cells through ERK1/2 and Smad signaling pathways in vitro. Biochem Pharmacol. 2015;93:49-58 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Tang D, Yu Y, Zhao X, Schachner M, Zhao W. Single chain fragment variable antibodies developed by using as target the 3rd fibronectin type III homologous repeat fragment of human neural cell adhesion molecule L1 promote cell migration and neuritogenesis. Exp Cell Res. 2015;330:336-45 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Kannike K, Sepp M, Zuccato C, Cattaneo E, Timmusk T. Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop. J Biol Chem. 2014;289:32845-57 pubmed 出版商
  • 免疫印迹; 人类; 1:800
Zhou X, Tao Y, Wang J, Liang C, Wang J, Li H, et al. Roles of FGF-2 and TGF-beta/FGF-2 on differentiation of human mesenchymal stem cells towards nucleus pulposus-like phenotype. Growth Factors. 2015;33:23-30 pubmed 出版商
  • 免疫印迹; 人类
Castorina A, Giunta S. Mucin 1 (MUC1) signalling contributes to increase the resistance to cell death in human bronchial epithelial cells exposed to nickel acetate. Biometals. 2014;27:1149-58 pubmed 出版商
  • 免疫印迹; 小鼠
Kapur N, Qiao X, Paruchuri V, Mackey E, Daly G, Ughreja K, et al. Reducing endoglin activity limits calcineurin and TRPC-6 expression and improves survival in a mouse model of right ventricular pressure overload. J Am Heart Assoc. 2014;3: pubmed 出版商
  • 免疫印迹; 人类
Attarha S, Andersson S, Mints M, Souchelnytskyi S. Mammalian sterile-like 1 kinase inhibits TGF? and EGF?dependent regulation of invasiveness, migration and proliferation of HEC-1-A endometrial cancer cells. Int J Oncol. 2014;45:853-60 pubmed 出版商
  • 免疫印迹; 兔; 1:1,000
Jiang Y, Kou Z, Wu T, An W, Zhou R, Wang H, et al. Xist deficiency and disorders of X-inactivation in rabbit embryonic stem cells can be rescued by transcription-factor-mediated conversion. Stem Cells Dev. 2014;23:2283-96 pubmed 出版商
  • 免疫印迹; 大鼠; 1:200
Castorina A, Scuderi S, D Amico A, Drago F, D Agata V. PACAP and VIP increase the expression of myelin-related proteins in rat schwannoma cells: involvement of PAC1/VPAC2 receptor-mediated activation of PI3K/Akt signaling pathways. Exp Cell Res. 2014;322:108-21 pubmed 出版商
  • 免疫印迹; 人类
Lin S, Hoffmann K, Xiao Z, Jin N, Galli U, Mohr E, et al. MEK inhibition induced downregulation of MRP1 and MRP3 expression in experimental hepatocellular carcinoma. Cancer Cell Int. 2013;13:3 pubmed 出版商
Li J, Liu X, Chen H, Sun Z, Chen H, Wang L, et al. Multi-targeting chemoprevention of Chinese herb formula Yanghe Huayan decoction on experimentally induced mammary tumorigenesis. BMC Complement Altern Med. 2019;19:48 pubmed 出版商
Di Nisio V, Rossi G, Iorio R, Pellegrini C, Macchiarelli G, Tiboni G, et al. VEGFR2 Expression Is Differently Modulated by Parity and Nulliparity in Mouse Ovary. Biomed Res Int. 2018;2018:6319414 pubmed 出版商
Tome Garcia J, Erfani P, Nudelman G, Tsankov A, Katsyv I, Tejero R, et al. Analysis of chromatin accessibility uncovers TEAD1 as a regulator of migration in human glioblastoma. Nat Commun. 2018;9:4020 pubmed 出版商
Nie X, Zheng J, Ricupero C, He L, Jiao K, Mao J. mTOR acts as a pivotal signaling hub for neural crest cells during craniofacial development. PLoS Genet. 2018;14:e1007491 pubmed 出版商
Zhang Y, Guo Z, Li M, Fong P, Zhang J, Zhang C, et al. Gabapentin Effects on PKC-ERK1/2 Signaling in the Spinal Cord of Rats with Formalin-Induced Visceral Inflammatory Pain. PLoS ONE. 2015;10:e0141142 pubmed 出版商
García Pérez D, Laorden M, Milanés M. Regulation of Pleiotrophin, Midkine, Receptor Protein Tyrosine Phosphatase β/ζ, and Their Intracellular Signaling Cascades in the Nucleus Accumbens During Opiate Administration. Int J Neuropsychopharmacol. 2015;19: pubmed 出版商
Attarha S, Saini R, Andersson S, Mints M, Souchelnytskyi S. PKN1 modulates TGFβ and EGF signaling in HEC-1-A endometrial cancer cell line. Onco Targets Ther. 2014;7:1397-408 pubmed 出版商
Tome Garcia J, Li D, Ghazaryan S, Shu L, Wu L. ERBB2 increases metastatic potentials specifically in androgen-insensitive prostate cancer cells. PLoS ONE. 2014;9:e99525 pubmed 出版商
Faggi F, Mitola S, Sorci G, Riuzzi F, Donato R, Codenotti S, et al. Phosphocaveolin-1 enforces tumor growth and chemoresistance in rhabdomyosarcoma. PLoS ONE. 2014;9:e84618 pubmed 出版商
Cruceru M, Enciu A, Popa A, Albulescu R, Neagu M, Tanase C, et al. Signal transduction molecule patterns indicating potential glioblastoma therapy approaches. Onco Targets Ther. 2013;6:1737-49 pubmed 出版商
Li Y, Gao C, Shi Y, Tang Y, Liu L, Xiong T, et al. Carbon monoxide alleviates ethanol-induced oxidative damage and inflammatory stress through activating p38 MAPK pathway. Toxicol Appl Pharmacol. 2013;273:53-8 pubmed 出版商
Burch T, Watson M, Nyalwidhe J. Variable metastatic potentials correlate with differential plectin and vimentin expression in syngeneic androgen independent prostate cancer cells. PLoS ONE. 2013;8:e65005 pubmed 出版商
Agrawal V, Smart K, Jilling T, Hirsch E. Surfactant protein (SP)-A suppresses preterm delivery and inflammation via TLR2. PLoS ONE. 2013;8:e63990 pubmed 出版商
Callero M, Luzzani G, De Dios D, Bradshaw T, Perez A. Biomarkers of sensitivity to potent and selective antitumor 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F203) in ovarian cancer. J Cell Biochem. 2013;114:2392-404 pubmed 出版商
Chappell J, Sun Y, Singh A, Dalton S. MYC/MAX control ERK signaling and pluripotency by regulation of dual-specificity phosphatases 2 and 7. Genes Dev. 2013;27:725-33 pubmed 出版商
Vrijens K, Lin W, Cui J, Farmer D, Low J, Pronier E, et al. Identification of small molecule activators of BMP signaling. PLoS ONE. 2013;8:e59045 pubmed 出版商
Du E, Li H, Jin S, Hu X, Qiu M, Han R. Evidence that TMEM67 causes polycystic kidney disease through activation of JNK/ERK-dependent pathways. Cell Biol Int. 2013;37:694-702 pubmed 出版商
Chen J, Guo Y, Cheng W, Chen R, Liu T, Chen Z, et al. High glucose induces apoptosis and suppresses proliferation of adult rat neural stem cells following in vitro ischemia. BMC Neurosci. 2013;14:24 pubmed 出版商
Cheng T, Zhang L, Fu X, Wang W, Xu H, Song H, et al. The potential protective effects of calcitonin involved in coordinating chondrocyte response, extracellular matrix, and subchondral trabecular bone in experimental osteoarthritis. Connect Tissue Res. 2013;54:139-46 pubmed 出版商
Nahid M, Yao B, Dominguez Gutierrez P, Kesavalu L, Satoh M, Chan E. Regulation of TLR2-mediated tolerance and cross-tolerance through IRAK4 modulation by miR-132 and miR-212. J Immunol. 2013;190:1250-63 pubmed 出版商
Huang L, Liu Y, Jin W, Ji X, Dong Z. Ketamine potentiates hippocampal neurodegeneration and persistent learning and memory impairment through the PKC?-ERK signaling pathway in the developing brain. Brain Res. 2012;1476:164-71 pubmed 出版商
García Navas R, Munder M, Mollinedo F. Depletion of L-arginine induces autophagy as a cytoprotective response to endoplasmic reticulum stress in human T lymphocytes. Autophagy. 2012;8:1557-76 pubmed 出版商
Breshears L, Schlievert P, Peterson M. A disintegrin and metalloproteinase 17 (ADAM17) and epidermal growth factor receptor (EGFR) signaling drive the epithelial response to Staphylococcus aureus toxic shock syndrome toxin-1 (TSST-1). J Biol Chem. 2012;287:32578-87 pubmed
Fisher K, Codina J, Petrovic S, Dubose T. Pyk2 regulates H+-ATPase-mediated proton secretion in the outer medullary collecting duct via an ERK1/2 signaling pathway. Am J Physiol Renal Physiol. 2012;303:F1353-62 pubmed 出版商
Straussman R, Morikawa T, Shee K, Barzily Rokni M, Qian Z, Du J, et al. Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion. Nature. 2012;487:500-4 pubmed 出版商
Batista T, Alonso Magdalena P, Vieira E, Amaral M, Cederroth C, Nef S, et al. Short-term treatment with bisphenol-A leads to metabolic abnormalities in adult male mice. PLoS ONE. 2012;7:e33814 pubmed 出版商
Stauber R, Knauer S, Habtemichael N, Bier C, Unruhe B, Weisheit S, et al. A combination of a ribonucleotide reductase inhibitor and histone deacetylase inhibitors downregulates EGFR and triggers BIM-dependent apoptosis in head and neck cancer. Oncotarget. 2012;3:31-43 pubmed
Okamura J, Huang Y, Moon D, Brait M, Chang X, Kim M. Downregulation of insulin-like growth factor-binding protein 7 in cisplatin-resistant non-small cell lung cancer. Cancer Biol Ther. 2012;13:148-55 pubmed 出版商
Mahmud H, Sillje H, Cannon M, van Gilst W, de Boer R. Regulation of the (pro)renin-renin receptor in cardiac remodelling. J Cell Mol Med. 2012;16:722-9 pubmed 出版商
Pancione M, Sabatino L, Fucci A, Carafa V, Nebbioso A, Forte N, et al. Epigenetic silencing of peroxisome proliferator-activated receptor ? is a biomarker for colorectal cancer progression and adverse patients' outcome. PLoS ONE. 2010;5:e14229 pubmed 出版商
Tsai F, Liu W, Pai M, Hsieh M, Lin J, Chou C. Downregulation of the integrin ?(v) signaling pathway in uterine leiomyomas. Gynecol Obstet Invest. 2011;71:129-35 pubmed 出版商
Zhang J, Luo W, Liu Z, Lin J, Cheng Z. Effects of transfection of ICAP-1? and its mutants on adhesion and migration of 2H-11 cells. J Huazhong Univ Sci Technolog Med Sci. 2010;30:569-74 pubmed 出版商
Palozza P, Colangelo M, Simone R, Catalano A, Boninsegna A, Lanza P, et al. Lycopene induces cell growth inhibition by altering mevalonate pathway and Ras signaling in cancer cell lines. Carcinogenesis. 2010;31:1813-21 pubmed 出版商
Alexandru O, Dragutescu L, Tataranu L, Ciubotaru V, Sevastre A, Georgescu A, et al. Helianthin induces antiproliferative effect on human glioblastoma cells in vitro. J Neurooncol. 2011;102:9-18 pubmed 出版商
Jadali A, Ghazizadeh S. Protein kinase D is implicated in the reversible commitment to differentiation in primary cultures of mouse keratinocytes. J Biol Chem. 2010;285:23387-97 pubmed 出版商
Li H, Han M, Bernier M, Zheng B, Sun S, Su M, et al. Krüppel-like factor 4 promotes differentiation by transforming growth factor-beta receptor-mediated Smad and p38 MAPK signaling in vascular smooth muscle cells. J Biol Chem. 2010;285:17846-56 pubmed 出版商
Elbaz J, Reizel Y, Nevo N, Galiani D, Dekel N. Epithelial cell transforming protein 2 (ECT2) depletion blocks polar body extrusion and generates mouse oocytes containing two metaphase II spindles. Endocrinology. 2010;151:755-65 pubmed 出版商
产品信息
产品名称 :
ERK 1/2(MK1)抗体
基因名称 :
MAPK3, MAPK1
规格 :
50微克/0.5毫升
价格 :
279美元
目录号 :
sc-135900
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
ERK 1/2
反应物种 :
m, r, h, 狗
应用 :
免疫印迹, 免疫沉淀, IF
表位 :
325-345(大鼠)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。