产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
IkappaB-alpha (H-4) Antibody
目录 :
sc-1643
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
H-4
反应物种 :
人类, 小鼠, brown rat
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 65
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 4a
Zoi I, Karamouzis M, Xingi E, Sarantis P, Thomaidou D, Lembessis P, et al. Combining RANK/RANKL and ERBB-2 targeting as a novel strategy in ERBB-2-positive breast carcinomas. Breast Cancer Res. 2019;21:132 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Meshram S, Paul D, Manne R, Choppara S, Sankaran G, Agrawal Y, et al. FBXO32 activates NF-κB through IκBα degradation in inflammatory and genotoxic stress. Int J Biochem Cell Biol. 2017;92:134-140 pubmed 出版商
  • 免疫印迹; 人类; 图 5g
Amigo Jiménez I, Bailón E, Aguilera Montilla N, García Marco J, García Pardo A. Gene expression profile induced by arsenic trioxide in chronic lymphocytic leukemia cells reveals a central role for heme oxygenase-1 in apoptosis and regulation of matrix metalloproteinase-9. Oncotarget. 2016;7:83359-83377 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Yu Y, Cui Y, Zhao Y, Liu S, Song G, Jiao P, et al. The binding capability of plasma phospholipid transfer protein, but not HDL pool size, is critical to repress LPS induced inflammation. Sci Rep. 2016;6:20845 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Amigo Jiménez I, Bailón E, Aguilera Montilla N, Terol M, García Marco J, García Pardo A. Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways. Oncotarget. 2015;6:44832-48 pubmed 出版商
  • 免疫印迹; 小鼠
He L, Zang A, Du M, Ma D, Yuan C, Zhou C, et al. mTOR regulates TLR-induced c-fos and Th1 responses to HBV and HCV vaccines. Virol Sin. 2015;30:174-89 pubmed 出版商
  • 免疫细胞化学; 人类; 图 7
House C, Wang B, Ceniccola K, Williams R, Simaan M, Olender J, et al. Voltage-gated Na+ Channel Activity Increases Colon Cancer Transcriptional Activity and Invasion Via Persistent MAPK Signaling. Sci Rep. 2015;5:11541 pubmed 出版商
  • 免疫印迹; brown rat; 图 2
Neira Peña T, Rojas Mancilla E, Munoz Vio V, Perez R, Gutierrez Hernandez M, Bustamante D, et al. Perinatal asphyxia leads to PARP-1 overactivity, p65 translocation, IL-1β and TNF-α overexpression, and apoptotic-like cell death in mesencephalon of neonatal rats: prevention by systemic neonatal nicotinamide administration. Neurotox Res. 2015;27:453-65 pubmed 出版商
  • 免疫印迹; brown rat; 1:200
Ortiz F, Acuña Castroviejo D, Doerrier C, Dayoub J, López L, Venegas C, et al. Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res. 2015;58:34-49 pubmed 出版商
  • 免疫印迹; 人类; 1:100
Chondrogiannis G, Kastamoulas M, Kanavaros P, Vartholomatos G, Bai M, Baltogiannis D, et al. Cytokine effects on cell viability and death of prostate carcinoma cells. Biomed Res Int. 2014;2014:536049 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 8e
Clauzure M, Valdivieso A, Massip Copiz M, Schulman G, Teiber M, Santa Coloma T. Disruption of interleukin-1? autocrine signaling rescues complex I activity and improves ROS levels in immortalized epithelial cells with impaired cystic fibrosis transmembrane conductance regulator (CFTR) function. PLoS ONE. 2014;9:e99257 pubmed 出版商
  • 免疫印迹; 小鼠
Hou J, Xia Y, Jiang R, Chen D, Xu J, Deng L, et al. PTPRO plays a dual role in hepatic ischemia reperfusion injury through feedback activation of NF-?B. J Hepatol. 2014;60:306-12 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类; 1:200
Fernandez G, Zaikos T, Khan S, Jacobi A, Behlke M, Zeichner S. Targeting I?B proteins for HIV latency activation: the role of individual I?B and NF-?B proteins. J Virol. 2013;87:3966-78 pubmed 出版商
Zhang Y, Dittmer D, Mieczkowski P, Host K, Fusco W, Duncan J, et al. RIG-I Detects Kaposi's Sarcoma-Associated Herpesvirus Transcripts in a RNA Polymerase III-Independent Manner. MBio. 2018;9: pubmed 出版商
Shukla K, Sonowal H, Saxena A, Ramana K. Didymin prevents hyperglycemia-induced human umbilical endothelial cells dysfunction and death. Biochem Pharmacol. 2018;152:1-10 pubmed 出版商
De Cicco P, Panza E, Armogida C, Ercolano G, Taglialatela Scafati O, Shokoohinia Y, et al. The Hydrogen Sulfide Releasing Molecule Acetyl Deacylasadisulfide Inhibits Metastatic Melanoma. Front Pharmacol. 2017;8:65 pubmed 出版商
Deruy E, Nassour J, Martin N, Vercamer C, Malaquin N, Bertout J, et al. Level of macroautophagy drives senescent keratinocytes into cell death or neoplastic evasion. Cell Death Dis. 2014;5:e1577 pubmed 出版商
Fasano E, Serini S, Mondella N, Trombino S, Celleno L, Lanza P, et al. Antioxidant and anti-inflammatory effects of selected natural compounds contained in a dietary supplement on two human immortalized keratinocyte lines. Biomed Res Int. 2014;2014:327452 pubmed 出版商
Salazar N, Vallejos X, Siryk A, Rengo G, Cannavo A, Liccardo D, et al. GRK2 blockade with ?ARKct is essential for cardiac ?2-adrenergic receptor signaling towards increased contractility. Cell Commun Signal. 2013;11:64 pubmed 出版商
Kastamoulas M, Chondrogiannis G, Kanavaros P, Vartholomatos G, Bai M, Briasoulis E, et al. Cytokine effects on cell survival and death of A549 lung carcinoma cells. Cytokine. 2013;61:816-25 pubmed 出版商
Chiba T, Itoh T, Tabuchi M, Nakazawa T, Satou T. Interleukin-1? accelerates the onset of stroke in stroke-prone spontaneously hypertensive rats. Mediators Inflamm. 2012;2012:701976 pubmed 出版商
Zhang N, Sun Q, Chen Z, Liu F, Jiang Y. Homeostatic regulatory role of Pokemon in NF-?B signaling: stimulating both p65 and I?B? expression in human hepatocellular carcinoma cells. Mol Cell Biochem. 2013;372:57-64 pubmed 出版商
Huang W, Shang W, Wang H, Wu W, Hou S. Sirt1 overexpression protects murine osteoblasts against TNF-?-induced injury in vitro by suppressing the NF-?B signaling pathway. Acta Pharmacol Sin. 2012;33:668-74 pubmed 出版商
Ndour P, Brocqueville G, Ouk T, Goormachtigh G, Morales O, Mougel A, et al. Inhibition of latent membrane protein 1 impairs the growth and tumorigenesis of latency II Epstein-Barr virus-transformed T cells. J Virol. 2012;86:3934-43 pubmed 出版商
Li C, Chao L, Wang S, Chang H, Tsai M, Fang S, et al. Honokiol inhibits LPS-induced maturation and inflammatory response of human monocyte-derived dendritic cells. J Cell Physiol. 2011;226:2338-49 pubmed 出版商
Kacimi R, Giffard R, Yenari M. Endotoxin-activated microglia injure brain derived endothelial cells via NF-?B, JAK-STAT and JNK stress kinase pathways. J Inflamm (Lond). 2011;8:7 pubmed 出版商
Janda E, Visalli V, Colica C, Aprigliano S, Musolino V, Vadalà N, et al. The protective effect of tianeptine on Gp120-induced apoptosis in astroglial cells: role of GS and NOS, and NF-?B suppression. Br J Pharmacol. 2011;164:1590-9 pubmed 出版商
Valovka T, Hottiger M. p65 controls NF-?B activity by regulating cellular localization of I?B?. Biochem J. 2011;434:253-63 pubmed 出版商
Bhaskaran N, Shukla S, Srivastava J, Gupta S. Chamomile: an anti-inflammatory agent inhibits inducible nitric oxide synthase expression by blocking RelA/p65 activity. Int J Mol Med. 2010;26:935-40 pubmed
Marcora E, Kennedy M. The Huntington's disease mutation impairs Huntingtin's role in the transport of NF-?B from the synapse to the nucleus. Hum Mol Genet. 2010;19:4373-84 pubmed 出版商
Zhu F, Dollé M, Berton T, Kuiper R, Capps C, Espejo A, et al. Mouse models for the p53 R72P polymorphism mimic human phenotypes. Cancer Res. 2010;70:5851-9 pubmed 出版商
Andújar I, Recio M, Bacelli T, Giner R, Rios J. Shikonin reduces oedema induced by phorbol ester by interfering with IkappaBalpha degradation thus inhibiting translocation of NF-kappaB to the nucleus. Br J Pharmacol. 2010;160:376-88 pubmed 出版商
Umenai T, Hirai H, Shime N, Nakaya T, Asahara T, Nomoto K, et al. Eradication of the commensal intestinal microflora by oral antimicrobials interferes with the host response to lipopolysaccharide. Eur J Clin Microbiol Infect Dis. 2010;29:633-41 pubmed 出版商
Cohen Saidon C, Cohen A, Sigal A, Liron Y, Alon U. Dynamics and variability of ERK2 response to EGF in individual living cells. Mol Cell. 2009;36:885-93 pubmed 出版商
Haddad O, Chotard Ghodsnia R, Verdier C, Duperray A. Tumor cell/endothelial cell tight contact upregulates endothelial adhesion molecule expression mediated by NFkappaB: differential role of the shear stress. Exp Cell Res. 2010;316:615-26 pubmed 出版商
Cetindere T, Nambiar S, Santourlidis S, Essmann F, Hassan M. Induction of indoleamine 2, 3-dioxygenase by death receptor activation contributes to apoptosis of melanoma cells via mitochondrial damage-dependent ROS accumulation. Cell Signal. 2010;22:197-211 pubmed 出版商
Bhushan S, Malik F, Kumar A, Isher H, Kaur I, Taneja S, et al. Activation of p53/p21/PUMA alliance and disruption of PI-3/Akt in multimodal targeting of apoptotic signaling cascades in cervical cancer cells by a pentacyclic triterpenediol from Boswellia serrata. Mol Carcinog. 2009;48:1093-108 pubmed 出版商
Petrof E, Claud E, Sun J, Abramova T, Guo Y, Waypa T, et al. Bacteria-free solution derived from Lactobacillus plantarum inhibits multiple NF-kappaB pathways and inhibits proteasome function. Inflamm Bowel Dis. 2009;15:1537-47 pubmed 出版商
Benitez D, Hermoso M, Pozo Guisado E, Fernandez Salguero P, Castellon E. Regulation of cell survival by resveratrol involves inhibition of NF kappa B-regulated gene expression in prostate cancer cells. Prostate. 2009;69:1045-54 pubmed 出版商
Nunes E, Kuczera D, Brito G, Bonatto S, Yamazaki R, Tanhoffer R, et al. Beta-hydroxy-beta-methylbutyrate supplementation reduces tumor growth and tumor cell proliferation ex vivo and prevents cachexia in Walker 256 tumor-bearing rats by modifying nuclear factor-kappaB expression. Nutr Res. 2008;28:487-93 pubmed 出版商
Wright C, Zhuang T, La P, Yang G, Dennery P. Hyperoxia-induced NF-kappaB activation occurs via a maturationally sensitive atypical pathway. Am J Physiol Lung Cell Mol Physiol. 2009;296:L296-306 pubmed 出版商
Jin X, Qiu L, Zhang D, Zhang M, Wang Z, Guo Z, et al. Chemosensitization in non-small cell lung cancer cells by IKK inhibitor occurs via NF-kappaB and mitochondrial cytochrome c cascade. J Cell Mol Med. 2009;13:4596-607 pubmed 出版商
Webster C, Kelly S, Koike M, Chock V, Giffard R, Yenari M. Inflammation and NFkappaB activation is decreased by hypothermia following global cerebral ischemia. Neurobiol Dis. 2009;33:301-12 pubmed 出版商
Pogson M, Holcombe M, Smallwood R, Qwarnstrom E. Introducing spatial information into predictive NF-kappaB modelling--an agent-based approach. PLoS ONE. 2008;3:e2367 pubmed 出版商
Jin X, Wang Z, Qiu L, Zhang D, Guo Z, Gao Z, et al. Potential biomarkers involving IKK/RelA signal in early stage non-small cell lung cancer. Cancer Sci. 2008;99:582-9 pubmed 出版商
Cai S, Brandt C. Induction of interleukin-6 in human retinal epithelial cells by an attenuated Herpes simplex virus vector requires viral replication and NFkappaB activation. Exp Eye Res. 2008;86:178-88 pubmed
Kim H, Yoon D, Lee W, Han S, Shrestha B, Kim C, et al. Phellinus linteus inhibits inflammatory mediators by suppressing redox-based NF-kappaB and MAPKs activation in lipopolysaccharide-induced RAW 264.7 macrophage. J Ethnopharmacol. 2007;114:307-15 pubmed
Feng G, Liu S, Wang G, Liu G. Lidocaine attenuates lipopolysaccharide-induced acute lung injury through inhibiting NF-kappaB activation. Pharmacology. 2008;81:32-40 pubmed
Merling R, Chen C, Hong S, Zhang L, Liu M, Kuo Y, et al. HTLV-1 Tax mutants that do not induce G1 arrest are disabled in activating the anaphase promoting complex. Retrovirology. 2007;4:35 pubmed
Zheng Z, Kim J, Ma H, Lee J, Yenari M. Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke. J Cereb Blood Flow Metab. 2008;28:53-63 pubmed
Kim H, Yoon D, Kim C, Shrestha B, Chang W, Lim S, et al. Ethanol extract of Inonotus obliquus inhibits lipopolysaccharide-induced inflammation in RAW 264.7 macrophage cells. J Med Food. 2007;10:80-9 pubmed
Romanatto T, Cesquini M, Amaral M, Roman E, Moraes J, Torsoni M, et al. TNF-alpha acts in the hypothalamus inhibiting food intake and increasing the respiratory quotient--effects on leptin and insulin signaling pathways. Peptides. 2007;28:1050-8 pubmed
Chiu J, Chen L, Lee C, Lee P, Lee D, Tsai M, et al. Mechanisms of induction of endothelial cell E-selectin expression by smooth muscle cells and its inhibition by shear stress. Blood. 2007;110:519-28 pubmed
Fernández Majada V, Aguilera C, Villanueva A, Vilardell F, Robert Moreno A, Aytes A, et al. Nuclear IKK activity leads to dysregulated notch-dependent gene expression in colorectal cancer. Proc Natl Acad Sci U S A. 2007;104:276-81 pubmed
Aguilera C, Fernández Majada V, Inglés Esteve J, Rodilla V, Bigas A, Espinosa L. Efficient nuclear export of p65-IkappaBalpha complexes requires 14-3-3 proteins. J Cell Sci. 2006;119:3695-704 pubmed
Hanashiro K, Sunagawa M, Tokeshi Y, Nakasone T, Ohta S, Nakamura M, et al. Antiallergic drugs, azelastine hydrochloride and epinastine hydrochloride, inhibit ongoing IgE secretion of rat IgE-producing hybridoma FE-3 cells. Eur J Pharmacol. 2006;547:174-83 pubmed
Wissel H, Burkhardt W, Rupp J, Wauer R, Rudiger M. Perfluorocarbons decrease Chlamydophila pneumoniae-mediated inflammatory responses of rat type II pneumocytes in vitro. Pediatr Res. 2006;60:264-9 pubmed
Redondo Muñoz J, Escobar Díaz E, Samaniego R, Terol M, Garcia Marco J, Garcia Pardo A. MMP-9 in B-cell chronic lymphocytic leukemia is up-regulated by alpha4beta1 integrin or CXCR4 engagement via distinct signaling pathways, localizes to podosomes, and is involved in cell invasion and migration. Blood. 2006;108:3143-51 pubmed
Goormachtigh G, Ouk T, Mougel A, Tranchand Bunel D, Masy E, Le Clorennec C, et al. Autoactivation of the Epstein-Barr virus oncogenic protein LMP1 during type II latency through opposite roles of the NF-kappaB and JNK signaling pathways. J Virol. 2006;80:7382-93 pubmed
Ogino T, Hosako M, Hiramatsu K, Omori M, Ozaki M, Okada S. Oxidative modification of IkappaB by monochloramine inhibits tumor necrosis factor alpha-induced NF-kappaB activation. Biochim Biophys Acta. 2005;1746:135-42 pubmed
Mun H, Aosai F, Norose K, Piao L, Fang H, Akira S, et al. Toll-like receptor 4 mediates tolerance in macrophages stimulated with Toxoplasma gondii-derived heat shock protein 70. Infect Immun. 2005;73:4634-42 pubmed
Conde R, Xavier J, McLoughlin C, Chinkers M, Ovsenek N. Protein phosphatase 5 is a negative modulator of heat shock factor 1. J Biol Chem. 2005;280:28989-96 pubmed
Yang J, Chen J, Luo L, Lin S, Li D, Hu S. Tetramethylpyrazine protected photoreceptor cells of rats by modulating nuclear translocation of NF-kappaB. Acta Pharmacol Sin. 2005;26:887-92 pubmed
Dieckhoff K, Graf P, Beinhauer B, Schwaerzler C, Carballido J, Neumann C, et al. Deficient translocation of c-Rel is associated with impaired Th1 cytokine production in T cells from atopic dermatitis patients. Exp Dermatol. 2005;14:17-25 pubmed
Löscher M, Fortschegger K, Ritter G, Wostry M, Voglauer R, Schmid J, et al. Interaction of U-box E3 ligase SNEV with PSMB4, the beta7 subunit of the 20 S proteasome. Biochem J. 2005;388:593-603 pubmed
产品信息
产品名称 :
IkappaB-alpha (H-4) Antibody
基因名称 :
NFKBIA
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-1643
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
IkappaB-alpha
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), FCM, 酶联免疫吸附测定
表位 :
1-317(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。