产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
Sox-2 (Y-17)
目录 :
sc-17320
共轭标签 :
未共轭
反应物种 :
African green monkey, 豚鼠, 人类, 小鼠, 大鼠, domestic rabbit
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, ChIP-Seq
更多信息或购买 :
文章摘录数: 125
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:500
Kindt K, Akturk A, Jarysta A, Day M, Beirl A, Flonard M, et al. EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia. Nat Commun. 2021;12:2861 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1d
Fu L, Hu Y, Song M, Liu Z, Zhang W, Yu F, et al. Up-regulation of FOXD1 by YAP alleviates senescence and osteoarthritis. PLoS Biol. 2019;17:e3000201 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 1f
Dong J, Pan Y, Wu X, He L, Liu X, Feng D, et al. A neuronal molecular switch through cell-cell contact that regulates quiescent neural stem cells. Sci Adv. 2019;5:eaav4416 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:2000; 图 4d
Koike T, Tanaka S, Hirahara Y, Oe S, Kurokawa K, Maeda M, et al. Morphological characteristics of p75 neurotrophin receptor-positive cells define a new type of glial cell in the rat dorsal root ganglia. J Comp Neurol. 2019;527:2047-2060 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 1b
Rajarajan P, Borrman T, Liao W, Schrode N, Flaherty E, Casiño C, et al. Neuron-specific signatures in the chromosomal connectome associated with schizophrenia risk. Science. 2018;362: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 2c
Zhang H, Pan H, Zhou C, Wei Y, Ying W, Li S, et al. Simultaneous zygotic inactivation of multiple genes in mouse through CRISPR/Cas9-mediated base editing. Development. 2018;145: pubmed 出版商
  • 免疫细胞化学; 人类; 图 s1d
Wang C, Najm R, Xu Q, Jeong D, Walker D, Balestra M, et al. Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. Nat Med. 2018;24:647-657 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 1b
Marrone L, Bus C, Schöndorf D, Fitzgerald J, Kübler M, Schmid B, et al. Generation of iPSCs carrying a common LRRK2 risk allele for in vitro modeling of idiopathic Parkinson's disease. PLoS ONE. 2018;13:e0192497 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 6d
Chen X, Wang R, Liu X, Wu Y, Zhou T, Yang Y, et al. A Chemical-Genetic Approach Reveals the Distinct Roles of GSK3? and GSK3? in Regulating Embryonic Stem Cell Fate. Dev Cell. 2017;43:563-576.e4 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1d
Hazim R, Karumbayaram S, Jiang M, Dimashkie A, Lopes V, Li D, et al. Differentiation of RPE cells from integration-free iPS cells and their cell biological characterization. Stem Cell Res Ther. 2017;8:217 pubmed 出版商
  • 免疫组化; 豚鼠; 1:100; 图 2b
Hatakeyama J, Sato H, Shimamura K. Developing guinea pig brain as a model for cortical folding. Dev Growth Differ. 2017;59:286-301 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s7a
Takahashi Y, Wu J, Suzuki K, Martínez Redondo P, Li M, Liao H, et al. Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells. Science. 2017;356:503-508 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Yan Y, Zhao W, Huang Y, Tong H, Xia Y, Jiang Q, et al. Loss of Polycomb Group Protein Pcgf1 Severely Compromises Proper Differentiation of Embryonic Stem Cells. Sci Rep. 2017;7:46276 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 1c
Feng W, Kawauchi D, Körkel Qu H, Deng H, Serger E, Sieber L, et al. Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme. Nat Commun. 2017;8:14758 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 7b
Barford K, Yap C, Dwyer N, Winckler B. The related neuronal endosomal proteins NEEP21 (Nsg1) and P19 (Nsg2) have divergent expression profiles in vivo. J Comp Neurol. 2017;525:1861-1878 pubmed 出版商
  • 免疫组化; 小鼠; 1:200; 图 1I
Bucks S, Cox B, Vlosich B, Manning J, Nguyen T, Stone J. Supporting cells remove and replace sensory receptor hair cells in a balance organ of adult mice. elife. 2017;6: pubmed 出版商
  • 流式细胞仪; domestic rabbit; 1:100; 图 2
Borghesi J, Mario L, Carreira A, Miglino M, Favaron P. Phenotype and multipotency of rabbit (Oryctolagus cuniculus) amniotic stem cells. Stem Cell Res Ther. 2017;8:27 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 2c
Korotkevich E, Niwayama R, Courtois A, Friese S, Berger N, Buchholz F, et al. The Apical Domain Is Required and Sufficient for the First Lineage Segregation in the Mouse Embryo. Dev Cell. 2017;40:235-247.e7 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1g
Bershteyn M, Nowakowski T, Pollen A, Di Lullo E, Nene A, Wynshaw Boris A, et al. Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia. Cell Stem Cell. 2017;20:435-449.e4 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4m
Shams Najafabadi H, Soheili Z, Samiei S, Ahmadieh H, Ranaei Pirmardan E, Masoumi M. Isolation, Characterization, and Establishment of Spontaneously Immortalized Cell Line HRPE-2S With Stem Cell Properties. J Cell Physiol. 2017;232:2626-2640 pubmed 出版商
  • ChIP-Seq; 小鼠; 图 5a
  • 免疫印迹; 小鼠; 图 s5g
Deluz C, Friman E, Strebinger D, Benke A, Raccaud M, Callegari A, et al. A role for mitotic bookmarking of SOX2 in pluripotency and differentiation. Genes Dev. 2016;30:2538-2550 pubmed
  • 免疫组化; 人类; 1:250; 图 1h
Retallack H, Di Lullo E, Arias C, Knopp K, Laurie M, Sandoval Espinosa C, et al. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. Proc Natl Acad Sci U S A. 2016;113:14408-14413 pubmed
  • 免疫组化; 小鼠
Fukunaga I, Fujimoto A, Hatakeyama K, Aoki T, Nishikawa A, Noda T, et al. In Vitro Models of GJB2-Related Hearing Loss Recapitulate Ca2+ Transients via a Gap Junction Characteristic of Developing Cochlea. Stem Cell Reports. 2016;7:1023-1036 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 图 s5b
Brooker S, Gobeske K, Chen J, Peng C, Kessler J. Hippocampal bone morphogenetic protein signaling mediates behavioral effects of antidepressant treatment. Mol Psychiatry. 2017;22:910-919 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 4
Zak M, van Oort T, Hendriksen F, Garcia M, Vassart G, Grolman W. LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea. Front Cell Neurosci. 2016;10:186 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:300; 图 s2a
Wang L, Hou S, Han Y. Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016;19:888-96 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50; 表 2
Cutts J, Brookhouser N, Brafman D. Generation of Regionally Specific Neural Progenitor Cells (NPCs) and Neurons from Human Pluripotent Stem Cells (hPSCs). Methods Mol Biol. 2016;1516:121-144 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:250; 图 3
Goodliffe J, Olmos Serrano J, Aziz N, Pennings J, Guedj F, Bianchi D, et al. Absence of Prenatal Forebrain Defects in the Dp(16)1Yey/+ Mouse Model of Down Syndrome. J Neurosci. 2016;36:2926-44 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 1g
Amadei G, Zander M, Yang G, Dumelie J, Vessey J, Lipshitz H, et al. A Smaug2-Based Translational Repression Complex Determines the Balance between Precursor Maintenance versus Differentiation during Mammalian Neurogenesis. J Neurosci. 2015;35:15666-81 pubmed 出版商
  • 免疫组化-冰冻切片; 人类; 图 1b
Thomsen E, Mich J, Yao Z, Hodge R, Doyle A, Jang S, et al. Fixed single-cell transcriptomic characterization of human radial glial diversity. Nat Methods. 2016;13:87-93 pubmed 出版商
  • 免疫细胞化学; African green monkey; 1:100; 图 1
Ramaswamy K, Yik W, Wang X, Oliphant E, Lu W, Shibata D, et al. Derivation of induced pluripotent stem cells from orangutan skin fibroblasts. BMC Res Notes. 2015;8:577 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 9
Martínez Revollar G, Garay E, Martín Tapia D, Nava P, Huerta M, Lopez Bayghen E, et al. Heterogeneity between triple negative breast cancer cells due to differential activation of Wnt and PI3K/AKT pathways. Exp Cell Res. 2015;339:67-80 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 3d
Higuchi Y, Nguyen C, Yasuda S, McMillan M, Hasegawa K, Kahn M. Specific Direct Small Molecule p300/?-Catenin Antagonists Maintain Stem Cell Potency. Curr Mol Pharmacol. 2016;9:272-279 pubmed
  • 免疫细胞化学; 小鼠; 1:200; 图 1b
Deleyrolle L, Sabourin J, Rothhut B, Fujita H, Guichet P, Teigell M, et al. OCAM regulates embryonic spinal cord stem cell proliferation by modulating ErbB2 receptor. PLoS ONE. 2015;10:e0122337 pubmed 出版商
Inak G, Rybak Wolf A, Lisowski P, Pentimalli T, Jüttner R, Glažar P, et al. Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome. Nat Commun. 2021;12:1929 pubmed 出版商
Liang C, Liu Z, Song M, Li W, Wu Z, Wang Z, et al. Stabilization of heterochromatin by CLOCK promotes stem cell rejuvenation and cartilage regeneration. Cell Res. 2021;31:187-205 pubmed 出版商
Zhang Y, Zhang S, Zhang Z, Dong Y, Ma X, Qiang R, et al. Knockdown of Foxg1 in Sox9+ supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse utricle. Aging (Albany NY). 2020;12:19834-19851 pubmed 出版商
Andrews M, Subramanian L, Kriegstein A. mTOR signaling regulates the morphology and migration of outer radial glia in developing human cortex. elife. 2020;9: pubmed 出版商
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Garland W, Comet I, Wu M, Radzisheuskaya A, Rib L, Vitting Seerup K, et al. A Functional Link between Nuclear RNA Decay and Transcriptional Control Mediated by the Polycomb Repressive Complex 2. Cell Rep. 2019;29:1800-1811.e6 pubmed 出版商
Mahmoudi S, Mancini E, Xu L, Moore A, Jahanbani F, Hebestreit K, et al. Heterogeneity in old fibroblasts is linked to variability in reprogramming and wound healing. Nature. 2019;574:553-558 pubmed 出版商
Oberst P, Fièvre S, Baumann N, Concetti C, Bartolini G, Jabaudon D. Temporal plasticity of apical progenitors in the developing mouse neocortex. Nature. 2019;573:370-374 pubmed 出版商
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Bonnefont J, Tiberi L, van den Ameele J, Potier D, Gaber Z, Lin X, et al. Cortical Neurogenesis Requires Bcl6-Mediated Transcriptional Repression of Multiple Self-Renewal-Promoting Extrinsic Pathways. Neuron. 2019;103:1096-1108.e4 pubmed 出版商
Deng L, Ren R, Liu Z, Song M, Li J, Wu Z, et al. Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis. Nat Commun. 2019;10:3329 pubmed 出版商
Gao L, Zhang Z, Lu J, Pei G. Mitochondria Are Dynamically Transferring Between Human Neural Cells and Alexander Disease-Associated GFAP Mutations Impair the Astrocytic Transfer. Front Cell Neurosci. 2019;13:316 pubmed 出版商
Canizo J, Ynsaurralde Rivolta A, Vázquez Echegaray C, Suvá M, Alberio V, Aller J, et al. A dose-dependent response to MEK inhibition determines hypoblast fate in bovine embryos. BMC Dev Biol. 2019;19:13 pubmed 出版商
Paredes B, Martins G, Azevedo C, Sampaio G, Nonaka C, Silva K, et al. Generation of three control iPS cell lines for sickle cell disease studies by reprogramming erythroblasts from individuals without hemoglobinopathies. Stem Cell Res. 2019;38:101454 pubmed 出版商
Wang X, Sterr M, Ansarullah -, Burtscher I, Böttcher A, Beckenbauer J, et al. Point mutations in the PDX1 transactivation domain impair human β-cell development and function. Mol Metab. 2019;24:80-97 pubmed 出版商
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Wei X, Guo J, Li Q, Jia Q, Jing Q, Li Y, et al. Bach1 regulates self-renewal and impedes mesendodermal differentiation of human embryonic stem cells. Sci Adv. 2019;5:eaau7887 pubmed 出版商
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Suvorova I, Knyazeva A, Petukhov A, Aksenov N, Pospelov V. Resveratrol enhances pluripotency of mouse embryonic stem cells by activating AMPK/Ulk1 pathway. Cell Death Discov. 2019;5:61 pubmed 出版商
Cheng S, Liu T, Hu Y, Xia Y, Hou J, Huang C, et al. Conditional Inactivation of Pen-2 in the Developing Neocortex Leads to Rapid Switch of Apical Progenitors to Basal Progenitors. J Neurosci. 2019;39:2195-2207 pubmed 出版商
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Khuu M, Pagan C, Nallamothu T, Hevner R, Hodge R, Ramirez J, et al. Intermittent Hypoxia Disrupts Adult Neurogenesis and Synaptic Plasticity in the Dentate Gyrus. J Neurosci. 2019;39:1320-1331 pubmed 出版商
Li H, Zhao C, Xu J, Xu Y, Cheng C, Liu Y, et al. Rapid generation of gene-targeted EPS-derived mouse models through tetraploid complementation. Protein Cell. 2019;10:20-30 pubmed 出版商
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Chen S, Xu K, Xie L, Cao H, Wu X, Du A, et al. The spatial distribution pattern of Connexin26 expression in supporting cells and its role in outer hair cell survival. Cell Death Dis. 2018;9:1180 pubmed 出版商
Chen X, Zhi X, Wang J, Su J. RANKL signaling in bone marrow mesenchymal stem cells negatively regulates osteoblastic bone formation. Bone Res. 2018;6:34 pubmed 出版商
Wan D, Morgan S, Spencley A, Mariano N, Chang E, Shankar G, et al. Honey bee Royalactin unlocks conserved pluripotency pathway in mammals. Nat Commun. 2018;9:5078 pubmed 出版商
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Martins G, Paredes B, Azevedo C, Sampaio G, Nonaka C, Cavalcante B, et al. Generation of integration-free iPS cell lines from three sickle cell disease patients from the state of Bahia, Brazil. Stem Cell Res. 2018;33:10-14 pubmed 出版商
Jiang K, Tang Z, Li J, Wang F, Tang N. Anxa4 mediated airway progenitor cell migration promotes distal epithelial cell fate specification. Sci Rep. 2018;8:14344 pubmed 出版商
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Mahapatra S, Martin D, Gallicano G. Re-Defining Stem Cell-Cardiomyocyte Interactions: Focusing on the Paracrine Effector Approach. J Stem Cells Regen Med. 2018;14:10-26 pubmed
Best S, Harapas C, Kersbergen A, Rathi V, Asselin Labat M, Sutherland K. FGFR3-TACC3 is an oncogenic fusion protein in respiratory epithelium. Oncogene. 2018;37:6096-6104 pubmed 出版商
Li J, Yuan Y, He J, Feng J, Han X, Jing J, et al. Constitutive activation of hedgehog signaling adversely affects epithelial cell fate during palatal fusion. Dev Biol. 2018;441:191-203 pubmed 出版商
Wang P, Liu Z, Zhang X, Li J, Sun L, Ju Z, et al. CRISPR/Cas9-mediated gene knockout reveals a guardian role of NF-κB/RelA in maintaining the homeostasis of human vascular cells. Protein Cell. 2018;9:945-965 pubmed 出版商
Castillo Azofeifa D, Seidel K, Gross L, Golden E, Jacquez B, Klein O, et al. SOX2 regulation by hedgehog signaling controls adult lingual epithelium homeostasis. Development. 2018;145: pubmed 出版商
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Wang C, Cui G, Liu X, Xu K, Wang M, Zhang X, et al. METTL3-mediated m6A modification is required for cerebellar development. PLoS Biol. 2018;16:e2004880 pubmed 出版商
Yeh W, Chiang H, Rees H, Edge A, Liu D. In vivo base editing of post-mitotic sensory cells. Nat Commun. 2018;9:2184 pubmed 出版商
Suzuki I, Gacquer D, Van Heurck R, Kumar D, Wojno M, Bilheu A, et al. Human-Specific NOTCH2NL Genes Expand Cortical Neurogenesis through Delta/Notch Regulation. Cell. 2018;173:1370-1384.e16 pubmed 出版商
Ghimire S, Ratzan E, Deans M. A non-autonomous function of the core PCP protein VANGL2 directs peripheral axon turning in the developing cochlea. Development. 2018;145: pubmed 出版商
Huang Y, Hill J, Yatteau A, Wong L, Jiang T, Petrovic J, et al. Reciprocal Negative Regulation Between Lmx1a and Lmo4 Is Required for Inner Ear Formation. J Neurosci. 2018;38:5429-5440 pubmed 出版商
Jiang M, Rao R, Wang J, Wang J, Xu L, Wu L, et al. The TSC1-mTOR-PLK axis regulates the homeostatic switch from Schwann cell proliferation to myelination in a stage-specific manner. Glia. 2018;66:1947-1959 pubmed 出版商
Johnson M, Sun X, Kodani A, Borges Monroy R, Girskis K, Ryu S, et al. Aspm knockout ferret reveals an evolutionary mechanism governing cerebral cortical size. Nature. 2018;556:370-375 pubmed 出版商
Storer M, Gallagher D, Fatt M, Simonetta J, Kaplan D, Miller F. Interleukin-6 Regulates Adult Neural Stem Cell Numbers during Normal and Abnormal Post-natal Development. Stem Cell Reports. 2018;10:1464-1480 pubmed 出版商
Ray T, Roy S, Kozlowski C, Wang J, Cafaro J, Hulbert S, et al. Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact. elife. 2018;7: pubmed 出版商
Jung M, Häberle B, Tschaikowsky T, Wittmann M, Balta E, Stadler V, et al. Analysis of the expression pattern of the schizophrenia-risk and intellectual disability gene TCF4 in the developing and adult brain suggests a role in development and plasticity of cortical and hippocampal neurons. Mol Autism. 2018;9:20 pubmed 出版商
Tu J, Tian G, Cheung H, Wei W, Lee T. Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells. Stem Cell Res Ther. 2018;9:71 pubmed 出版商
Atkinson P, Dong Y, Gu S, Liu W, Najarro E, Udagawa T, et al. Sox2 haploinsufficiency primes regeneration and Wnt responsiveness in the mouse cochlea. J Clin Invest. 2018;128:1641-1656 pubmed 出版商
Guallar D, Bi X, Pardavila J, Huang X, Sáenz C, Shi X, et al. RNA-dependent chromatin targeting of TET2 for endogenous retrovirus control in pluripotent stem cells. Nat Genet. 2018;50:443-451 pubmed 出版商
Wu Z, Zhang W, Song M, Wang W, Wei G, Li W, et al. Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome. Protein Cell. 2018;9:333-350 pubmed 出版商
Silva C, Peyre E, Adhikari M, Tielens S, Tanco S, Van Damme P, et al. Cell-Intrinsic Control of Interneuron Migration Drives Cortical Morphogenesis. Cell. 2018;172:1063-1078.e19 pubmed 出版商
Wang S, Hu B, Ding Z, Dang Y, Wu J, Li D, et al. ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells. Cell Discov. 2018;4:2 pubmed 出版商
Wang X, Sterr M, Burtscher I, Chen S, Hieronimus A, Machicao F, et al. Genome-wide analysis of PDX1 target genes in human pancreatic progenitors. Mol Metab. 2018;9:57-68 pubmed 出版商
Chen S, Xie L, Xu K, Cao H, Wu X, Xu X, et al. Developmental abnormalities in supporting cell phalangeal processes and cytoskeleton in the Gjb2 knockdown mouse model. Dis Model Mech. 2018;11: pubmed 出版商
Mikheev A, Mikheeva S, Tokita M, Severs L, Rostomily R. Twist1 mediated regulation of glioma tumorigenicity is dependent on mode of mouse neural progenitor transformation. Oncotarget. 2017;8:107716-107729 pubmed 出版商
Gao X, Tao Y, Lamas V, Huang M, Yeh W, Pan B, et al. Treatment of autosomal dominant hearing loss by in vivo delivery of genome editing agents. Nature. 2018;553:217-221 pubmed 出版商
Scior A, Buntru A, Arnsburg K, Ast A, Iburg M, Juenemann K, et al. Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex. EMBO J. 2018;37:282-299 pubmed 出版商
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