Nishino K, Nishiko Y, Shibata M, Oda Y, Watanabe E, Niimi K, et al. Cell surface membrane lysosome-associated membrane glycoprotein 2 promotes cell adhesion via abundant N-glycans in choriocarcinoma. Placenta. 2022;117:109-117 pubmed 出版商

Wang J, Zhou C, Khodabukus A, Tran S, Han S, Carlson A, et al. Three-dimensional tissue-engineered human skeletal muscle model of Pompe disease. Commun Biol. 2021;4:524 pubmed 出版商

Charrin S, Palmulli R, Billard M, Clay D, Boucheix C, van Niel G, et al. Rapid Isolation of Rare Isotype-Switched Hybridoma Variants: Application to the Generation of IgG2a and IgG2b MAb to CD63, a Late Endosome and Exosome Marker. Antibodies (Basel). 2020;9: pubmed 出版商

Reventun P, Sanchez Esteban S, Cook A, Cuadrado I, Roza C, Moreno Gómez Toledano R, et al. Bisphenol A induces coronary endothelial cell necroptosis by activating RIP3/CamKII dependent pathway. Sci Rep. 2020;10:4190 pubmed 出版商

Perenthaler E, Nikoncuk A, Yousefi S, Berdowski W, Alsagob M, Capo I, et al. Loss of UGP2 in brain leads to a severe epileptic encephalopathy, emphasizing that bi-allelic isoform-specific start-loss mutations of essential genes can cause genetic diseases. Acta Neuropathol. 2020;139:415-442 pubmed 出版商

Achberger K, Probst C, Haderspeck J, Bolz S, Rogal J, Chuchuy J, et al. Merging organoid and organ-on-a-chip technology to generate complex multi-layer tissue models in a human retina-on-a-chip platform. elife. 2019;8: pubmed 出版商

He R, Wang M, Zhao C, Shen M, Yu Y, He L, et al. TFEB-driven autophagy potentiates TGF-β induced migration in pancreatic cancer cells. J Exp Clin Cancer Res. 2019;38:340 pubmed 出版商

Birket M, Raibaud S, Lettieri M, Adamson A, Letang V, Cervello P, et al. A Human Stem Cell Model of Fabry Disease Implicates LIMP-2 Accumulation in Cardiomyocyte Pathology. Stem Cell Reports. 2019;13:380-393 pubmed 出版商

Xu Y, Zhou P, Cheng S, Lu Q, Nowak K, Hopp A, et al. A Bacterial Effector Reveals the V-ATPase-ATG16L1 Axis that Initiates Xenophagy. Cell. 2019;178:552-566.e20 pubmed 出版商

Talreja J, Talwar H, Bauerfeld C, Grossman L, Zhang K, Tranchida P, et al. HIF-1α regulates IL-1β and IL-17 in sarcoidosis. elife. 2019;8: pubmed 出版商

Mao D, Lin G, Tepe B, Zuo Z, Tan K, Senturk M, et al. VAMP associated proteins are required for autophagic and lysosomal degradation by promoting a PtdIns4P-mediated endosomal pathway. Autophagy. 2019;15:1214-1233 pubmed 出版商

Hsu C, Lee E, Gordon K, Paz E, Shen W, Ohnishi K, et al. MAP4K3 mediates amino acid-dependent regulation of autophagy via phosphorylation of TFEB. Nat Commun. 2018;9:942 pubmed 出版商

Wu W, Grotefend C, Tsai M, Wang Y, Radic V, Eoh H, et al. ?20 IFITM2 differentially restricts X4 and R5 HIV-1. Proc Natl Acad Sci U S A. 2017;114:7112-7117 pubmed 出版商

Bakula D, Müller A, Zuleger T, Takacs Z, Franz Wachtel M, Thost A, et al. WIPI3 and WIPI4 β-propellers are scaffolds for LKB1-AMPK-TSC signalling circuits in the control of autophagy. Nat Commun. 2017;8:15637 pubmed 出版商

Jia X, Chen J, Megger D, Zhang X, Kozlowski M, Zhang L, et al. Label-free Proteomic Analysis of Exosomes Derived from Inducible Hepatitis B Virus-Replicating HepAD38 Cell Line. Mol Cell Proteomics. 2017;16:S144-S160 pubmed 出版商

Wolfson R, Chantranupong L, Wyant G, Gu X, Orozco J, Shen K, et al. KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1. Nature. 2017;543:438-442 pubmed 出版商

Hammerling B, Najor R, Cortez M, Shires S, Leon L, Gonzalez E, et al. A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Nat Commun. 2017;8:14050 pubmed 出版商

Koh H, Kim Y, Kim J, Yun J, Jang K, Yang C. Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKCα. PLoS Pathog. 2017;13:e1006126 pubmed 出版商

Ruf S, Heberle A, Langelaar Makkinje M, Gelino S, Wilkinson D, Gerbeth C, et al. PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagy. Autophagy. 2017;13:486-505 pubmed 出版商

Matsumoto A, Pasut A, Matsumoto M, Yamashita R, Fung J, Monteleone E, et al. mTORC1 and muscle regeneration are regulated by the LINC00961-encoded SPAR polypeptide. Nature. 2017;541:228-232 pubmed 出版商

Pourcelot M, Zemirli N, Silva da Costa L, Loyant R, Garcin D, Vitour D, et al. The Golgi apparatus acts as a platform for TBK1 activation after viral RNA sensing. BMC Biol. 2016;14:69 pubmed 出版商

McLelland G, Lee S, McBride H, Fon E. Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system. J Cell Biol. 2016;214:275-91 pubmed 出版商

Fernández B, Fdez E, Gomez Suaga P, Gil F, Molina Villalba I, Ferrer I, et al. Iron overload causes endolysosomal deficits modulated by NAADP-regulated 2-pore channels and RAB7A. Autophagy. 2016;12:1487-506 pubmed 出版商

Agarwal S, Bell C, Taylor S, Moran R. p53 Deletion or Hotspot Mutations Enhance mTORC1 Activity by Altering Lysosomal Dynamics of TSC2 and Rheb. Mol Cancer Res. 2016;14:66-77 pubmed 出版商

Xia H, Najafov A, Geng J, Galan Acosta L, Han X, Guo Y, et al. Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death. J Cell Biol. 2015;210:705-16 pubmed 出版商

Ju X, Yan Y, Liu Q, Li N, Sheng M, Zhang L, et al. Neuraminidase of Influenza A Virus Binds Lysosome-Associated Membrane Proteins Directly and Induces Lysosome Rupture. J Virol. 2015;89:10347-58 pubmed 出版商

Nezich C, Wang C, Fogel A, Youle R. MiT/TFE transcription factors are activated during mitophagy downstream of Parkin and Atg5. J Cell Biol. 2015;210:435-50 pubmed 出版商

Thomas A, Mariani Floderer C, López Huertas M, Gros N, Hamard Péron E, Favard C, et al. Involvement of the Rac1-IRSp53-Wave2-Arp2/3 Signaling Pathway in HIV-1 Gag Particle Release in CD4 T Cells. J Virol. 2015;89:8162-81 pubmed 出版商

Kommaddi R, Jean Charles P, Shenoy S. Phosphorylation of the deubiquitinase USP20 by protein kinase A regulates post-endocytic trafficking of β2 adrenergic receptors to autophagosomes during physiological stress. J Biol Chem. 2015;290:8888-903 pubmed 出版商

Gotink K, Rovithi M, de Haas R, Honeywell R, Dekker H, Poel D, et al. Cross-resistance to clinically used tyrosine kinase inhibitors sunitinib, sorafenib and pazopanib. Cell Oncol (Dordr). 2015;38:119-29 pubmed 出版商

Rebsamen M, Pochini L, Stasyk T, de Araújo M, Galluccio M, Kandasamy R, et al. SLC38A9 is a component of the lysosomal amino acid sensing machinery that controls mTORC1. Nature. 2015;519:477-81 pubmed 出版商

Dowdle W, Nyfeler B, Nagel J, Elling R, Liu S, Triantafellow E, et al. Selective VPS34 inhibitor blocks autophagy and uncovers a role for NCOA4 in ferritin degradation and iron homeostasis in vivo. Nat Cell Biol. 2014;16:1069-79 pubmed 出版商

Ribeiro Rodrigues T, Catarino S, Marques C, Ferreira J, Martins Marques T, Pereira P, et al. AMSH-mediated deubiquitination of Cx43 regulates internalization and degradation of gap junctions. FASEB J. 2014;28:4629-41 pubmed 出版商

Itier J, Ret G, Viale S, Sweet L, Bangari D, Caron A, et al. Effective clearance of GL-3 in a human iPSC-derived cardiomyocyte model of Fabry disease. J Inherit Metab Dis. 2014;37:1013-22 pubmed 出版商

Smith R, Solberg R, Jacobsen L, Voreland A, Rustan A, Thoresen G, et al. Simvastatin inhibits glucose metabolism and legumain activity in human myotubes. PLoS ONE. 2014;9:e85721 pubmed 出版商

Cai K, Lucki N, Sewer M. Silencing diacylglycerol kinase-theta expression reduces steroid hormone biosynthesis and cholesterol metabolism in human adrenocortical cells. Biochim Biophys Acta. 2014;1841:552-62 pubmed 出版商

Han J, Hou W, Lu C, Goldstein L, Stolz D, Watkins S, et al. Interaction between Her2 and Beclin-1 proteins underlies a new mechanism of reciprocal regulation. J Biol Chem. 2013;288:20315-25 pubmed 出版商

Haugen M, Johansen H, Pettersen S, Solberg R, Brix K, Flatmark K, et al. Nuclear legumain activity in colorectal cancer. PLoS ONE. 2013;8:e52980 pubmed 出版商

Abokyi S, Shan S, To C, Chan H, Tse D. Autophagy Upregulation by the TFEB Inducer Trehalose Protects against Oxidative Damage and Cell Death Associated with NRF2 Inhibition in Human RPE Cells. Oxid Med Cell Longev. 2020;2020:5296341 pubmed 出版商

Mutvei A, Nagiec M, Hamann J, Kim S, Vincent C, Blenis J. Rap1-GTPases control mTORC1 activity by coordinating lysosome organization with amino acid availability. Nat Commun. 2020;11:1416 pubmed 出版商

Arrant A, Roth J, Boyle N, Kashyap S, Hoffmann M, Murchison C, et al. Impaired β-glucocerebrosidase activity and processing in frontotemporal dementia due to progranulin mutations. Acta Neuropathol Commun. 2019;7:218 pubmed 出版商

Wang B, Xiao X, Huang F, Liu R. Syntaxin-17-Dependent Mitochondrial Dynamics is Essential for Protection Against Oxidative-Stress-Induced Apoptosis. Antioxidants (Basel). 2019;8: pubmed 出版商

Chung C, Shin H, Berdan C, Ford B, Ward C, Olzmann J, et al. Covalent targeting of the vacuolar H+-ATPase activates autophagy via mTORC1 inhibition. Nat Chem Biol. 2019;15:776-785 pubmed 出版商

Jung J, Macalino S, Cui M, Kim J, Kim H, Song D, et al. Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling. Cell Metab. 2019;29:1306-1319.e7 pubmed 出版商

Bouhamdani N, Comeau D, Cormier K, Turcotte S. STF-62247 accumulates in lysosomes and blocks late stages of autophagy to selectively target von Hippel-Lindau-inactivated cells. Am J Physiol Cell Physiol. 2019;316:C605-C620 pubmed 出版商

Chun J, Zhang J, Wilkins M, Subramanian B, Riella C, Magraner J, et al. Recruitment of APOL1 kidney disease risk variants to lipid droplets attenuates cell toxicity. Proc Natl Acad Sci U S A. 2019;116:3712-3721 pubmed 出版商

Ericksen R, Lim S, McDonnell E, Shuen W, Vadiveloo M, White P, et al. Loss of BCAA Catabolism during Carcinogenesis Enhances mTORC1 Activity and Promotes Tumor Development and Progression. Cell Metab. 2019;: pubmed 出版商

Wang R, Tan J, Chen T, Han H, Tian R, Tan Y, et al. ATP13A2 facilitates HDAC6 recruitment to lysosome to promote autophagosome-lysosome fusion. J Cell Biol. 2019;218:267-284 pubmed 出版商

Kory N, Wyant G, Prakash G, Uit de Bos J, Bottanelli F, Pacold M, et al. SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism. Science. 2018;362: pubmed 出版商

Kim J, Kim Y, Lee H, Jin H, Neupane C, Kim S, et al. GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections. Nat Commun. 2018;9:4184 pubmed 出版商

Yao Z, Qiao Y, Li X, Chen J, Ding J, Bai L, et al. Exosomes Exploit the Virus Entry Machinery and Pathway To Transmit Alpha Interferon-Induced Antiviral Activity. J Virol. 2018;92: pubmed 出版商

Lee J, Xu Y, Zhang T, Cui L, Saidi L, Ye Y. Secretion of misfolded cytosolic proteins from mammalian cells is independent of chaperone-mediated autophagy. J Biol Chem. 2018;293:14359-14370 pubmed 出版商

Wang W, Xia Z, Farre J, Subramani S. TRIM37 deficiency induces autophagy through deregulating the MTORC1-TFEB axis. Autophagy. 2018;14:1574-1585 pubmed 出版商

Guttmann S, Bernick F, Naorniakowska M, Michgehl U, Groba S, Socha P, et al. Functional Characterization of Novel ATP7B Variants for Diagnosis of Wilson Disease. Front Pediatr. 2018;6:106 pubmed 出版商

Yu Z, Surface L, Park C, Horlbeck M, Wyant G, Abu Remaileh M, et al. Identification of a transporter complex responsible for the cytosolic entry of nitrogen-containing bisphosphonates. elife. 2018;7: pubmed 出版商

Li Z, Kong Y, Song L, Luo Q, Liu J, Shao C, et al. Plk1-Mediated Phosphorylation of TSC1 Enhances the Efficacy of Rapamycin. Cancer Res. 2018;78:2864-2875 pubmed 出版商

Fu R, Deng Q, Zhang H, Hu X, Li Y, Liu Y, et al. A novel autophagy inhibitor berbamine blocks SNARE-mediated autophagosome-lysosome fusion through upregulation of BNIP3. Cell Death Dis. 2018;9:243 pubmed 出版商

Pei G, Buijze H, Liu H, Moura Alves P, Goosmann C, Brinkmann V, et al. The E3 ubiquitin ligase NEDD4 enhances killing of membrane-perturbing intracellular bacteria by promoting autophagy. Autophagy. 2017;13:2041-2055 pubmed 出版商

Colasuonno F, Borghi R, Niceforo A, Muzzi M, Bertini E, Di Giulio A, et al. Senescence-associated ultrastructural features of long-term cultures of induced pluripotent stem cells (iPSCs). Aging (Albany NY). 2017;9:2209-2222 pubmed 出版商

Kim S, Yang C, Lee H, Kim J, Kim Y, Kim Y, et al. ESRRA (estrogen-related receptor α) is a key coordinator of transcriptional and post-translational activation of autophagy to promote innate host defense. Autophagy. 2018;14:152-168 pubmed 出版商

Willy J, Young S, Mosley A, Gawrieh S, Stevens J, Masuoka H, et al. Function of inhibitor of Bruton's tyrosine kinase isoform ? (IBTK?) in nonalcoholic steatohepatitis links autophagy and the unfolded protein response. J Biol Chem. 2017;292:14050-14065 pubmed 出版商

Ainscough J, MacLeod T, McGonagle D, Brakefield R, Baron J, Alase A, et al. Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36?. Proc Natl Acad Sci U S A. 2017;114:E2748-E2757 pubmed 出版商

Li C, Luo X, Zhao S, Siu G, Liang Y, Chan H, et al. COPI-TRAPPII activates Rab18 and regulates its lipid droplet association. EMBO J. 2017;36:441-457 pubmed 出版商

Kim J, Lee H, Park K, Shin D, Kim T, Kim Y, et al. MIR144* inhibits antimicrobial responses against Mycobacterium tuberculosis in human monocytes and macrophages by targeting the autophagy protein DRAM2. Autophagy. 2017;13:423-441 pubmed 出版商

Kwon J, Willy J, Quirin K, Wek R, Korc M, Yin X, et al. Novel role of miR-29a in pancreatic cancer autophagy and its therapeutic potential. Oncotarget. 2016;7:71635-71650 pubmed 出版商

Ferreira J, Soares A, Ramalho J, Pereira P, Girao H. K63 linked ubiquitin chain formation is a signal for HIF1A degradation by Chaperone-Mediated Autophagy. Sci Rep. 2015;5:10210 pubmed 出版商

Gotink K, Broxterman H, Honeywell R, Dekker H, de Haas R, Miles K, et al. Acquired tumor cell resistance to sunitinib causes resistance in a HT-29 human colon cancer xenograft mouse model without affecting sunitinib biodistribution or the tumor microvasculature. Oncoscience. 2014;1:844-53 pubmed

Nardacci R, Amendola A, Ciccosanti F, Corazzari M, Esposito V, Vlassi C, et al. Autophagy plays an important role in the containment of HIV-1 in nonprogressor-infected patients. Autophagy. 2014;10:1167-78 pubmed 出版商

Kondratskyi A, Yassine M, Slomianny C, Kondratska K, Gordienko D, Dewailly E, et al. Identification of ML-9 as a lysosomotropic agent targeting autophagy and cell death. Cell Death Dis. 2014;5:e1193 pubmed 出版商

Yamano K, Fogel A, Wang C, van der Bliek A, Youle R. Mitochondrial Rab GAPs govern autophagosome biogenesis during mitophagy. elife. 2014;3:e01612 pubmed 出版商

Wu C, Martel J, Cheng W, He C, Ojcius D, Young J. Membrane vesicles nucleate mineralo-organic nanoparticles and induce carbonate apatite precipitation in human body fluids. J Biol Chem. 2013;288:30571-84 pubmed 出版商

Ferreira J, Fôfo H, Bejarano E, Bento C, Ramalho J, Girao H, et al. STUB1/CHIP is required for HIF1A degradation by chaperone-mediated autophagy. Autophagy. 2013;9:1349-66 pubmed 出版商

Salem A, Al Zoubi M, Whitaker Menezes D, Martinez Outschoorn U, Lamb R, Hulit J, et al. Cigarette smoke metabolically promotes cancer, via autophagy and premature aging in the host stromal microenvironment. Cell Cycle. 2013;12:818-25 pubmed 出版商

Ding Y, Liu Z, Desai S, Zhao Y, Liu H, Pannell L, et al. Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism. Nat Commun. 2012;3:1271 pubmed 出版商

Zou Z, Yuan Z, Zhang Q, Long Z, Chen J, Tang Z, et al. Aurora kinase A inhibition-induced autophagy triggers drug resistance in breast cancer cells. Autophagy. 2012;8:1798-810 pubmed 出版商

Lucki N, Li D, Bandyopadhyay S, Wang E, Merrill A, Sewer M. Acid ceramidase (ASAH1) represses steroidogenic factor 1-dependent gene transcription in H295R human adrenocortical cells by binding to the receptor. Mol Cell Biol. 2012;32:4419-31 pubmed 出版商

Hong S, Mannan A, Inoki K. Evaluation of the nutrient-sensing mTOR pathway. Methods Mol Biol. 2012;821:29-44 pubmed 出版商

Gotink K, Broxterman H, Labots M, de Haas R, Dekker H, Honeywell R, et al. Lysosomal sequestration of sunitinib: a novel mechanism of drug resistance. Clin Cancer Res. 2011;17:7337-46 pubmed 出版商

Castello Cros R, Bonuccelli G, Molchansky A, Capozza F, Witkiewicz A, Birbe R, et al. Matrix remodeling stimulates stromal autophagy, "fueling" cancer cell mitochondrial metabolism and metastasis. Cell Cycle. 2011;10:2021-34 pubmed

Gargini R, García Escudero V, Izquierdo M. Therapy mediated by mitophagy abrogates tumor progression. Autophagy. 2011;7:466-76 pubmed

Hou W, Han J, Lu C, Goldstein L, Rabinowich H. Autophagic degradation of active caspase-8: a crosstalk mechanism between autophagy and apoptosis. Autophagy. 2010;6:891-900 pubmed 出版商

Ju J, Varadhachary A, Miller S, Weihl C. Quantitation of "autophagic flux" in mature skeletal muscle. Autophagy. 2010;6:929-35 pubmed 出版商

Tresse E, Salomons F, Vesa J, Bott L, Kimonis V, Yao T, et al. VCP/p97 is essential for maturation of ubiquitin-containing autophagosomes and this function is impaired by mutations that cause IBMPFD. Autophagy. 2010;6:217-27 pubmed

Dilli E, Dodick D. Extracephalic cluster (cluster sine headache). Neurology. 2008;70:1362-3 pubmed 出版商

van der Kooi A, Van Langen I, Aronica E, Van Doorn P, Wokke J, Brusse E, et al. Extension of the clinical spectrum of Danon disease. Neurology. 2008;70:1358-9 pubmed 出版商