产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
c-Abl (24-11) Antibody
目录 :
sc-23
规格 :
100微克/毫升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
24-11
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
文章摘录数: 35
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 s2a
Yuan B, Yang J, Dubeau L, Hu Y, Li R. A Phosphotyrosine Switch in Estrogen Receptor β Is Required for Mouse Ovarian Function. Front Cell Dev Biol. 2021;9:649087 pubmed 出版商
  • 免疫印迹; 人类; 图 4c
Kim B, Jeong Y, Wong M, Martin L. DNA damage accumulates and responses are engaged in human ALS brain and spinal motor neurons and DNA repair is activatable in iPSC-derived motor neurons with SOD1 mutations. Acta Neuropathol Commun. 2020;8:7 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1s1a
Langer L, Ward J, Archer T. Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination. elife. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5d
Gerlach B, Tubbesing K, Liao G, Rezey A, Wang R, Barroso M, et al. Phosphorylation of GMFγ by c-Abl Coordinates Lamellipodial and Focal Adhesion Dynamics to Regulate Airway Smooth Muscle Cell Migration. Am J Respir Cell Mol Biol. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 图 4
Wang Z, Zhang Y, Pinkas D, Fox A, Luo J, Huang H, et al. Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2- a]pyrazin-3-ylethynyl)-4-isopropyl- N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2. J Med Chem. 2018;: pubmed 出版商
  • 免疫印迹; 人类; 图 1
Bilal M, Zhang E, Dinkel B, Hardy D, Yankee T, Houtman J. GADS is required for TCR-mediated calcium influx and cytokine release, but not cellular adhesion, in human T cells. Cell Signal. 2015;27:841-50 pubmed 出版商
  • 免疫印迹; 人类
Bernusso V, Machado Neto J, Pericole F, Vieira K, Duarte A, Traina F, et al. Imatinib restores VASP activity and its interaction with Zyxin in BCR-ABL leukemic cells. Biochim Biophys Acta. 2015;1853:388-95 pubmed 出版商
  • 免疫沉淀; 大鼠
  • 免疫细胞化学; 大鼠
Vargas L, Leal N, Estrada L, González A, Serrano F, Araya K, et al. EphA4 activation of c-Abl mediates synaptic loss and LTP blockade caused by amyloid-β oligomers. PLoS ONE. 2014;9:e92309 pubmed 出版商
García Tuñón I, Hernández Sánchez M, Ordoñez J, Alonso Pérez V, Álamo Quijada M, Benito R, et al. The CRISPR/Cas9 system efficiently reverts the tumorigenic ability of BCR/ABL in vitro and in a xenograft model of chronic myeloid leukemia. Oncotarget. 2017;8:26027-26040 pubmed 出版商
Ananthula S, Sinha A, El Gassim M, Batth S, Marshall G, Gardner L, et al. Geminin overexpression-dependent recruitment and crosstalk with mesenchymal stem cells enhance aggressiveness in triple negative breast cancers. Oncotarget. 2016;7:20869-89 pubmed 出版商
Blanchard Z, Mullins N, Ellipeddi P, Lage J, McKinney S, El Etriby R, et al. Geminin overexpression promotes imatinib sensitive breast cancer: a novel treatment approach for aggressive breast cancers, including a subset of triple negative. PLoS ONE. 2014;9:e95663 pubmed 出版商
Salem T, Gomard T, Court F, Moquet Torcy G, Brockly F, Forné T, et al. Chromatin loop organization of the junb locus in mouse dendritic cells. Nucleic Acids Res. 2013;41:8908-25 pubmed 出版商
Liu Y, Zheng W, Song Y, Ma W, Yin H. Low expression of miR-196b enhances the expression of BCR-ABL1 and HOXA9 oncogenes in chronic myeloid leukemogenesis. PLoS ONE. 2013;8:e68442 pubmed 出版商
Panjarian S, Iacob R, Chen S, Wales T, Engen J, Smithgall T. Enhanced SH3/linker interaction overcomes Abl kinase activation by gatekeeper and myristic acid binding pocket mutations and increases sensitivity to small molecule inhibitors. J Biol Chem. 2013;288:6116-29 pubmed 出版商
Liu Y, Song Y, Ma W, Zheng W, Yin H. Decreased microRNA-30a levels are associated with enhanced ABL1 and BCR-ABL1 expression in chronic myeloid leukemia. Leuk Res. 2013;37:349-56 pubmed 出版商
Amengual Cladera E, Llado I, Proenza A, Gianotti M. High-fat diet feeding induces a depot-dependent response on the pro-inflammatory state and mitochondrial function of gonadal white adipose tissue. Br J Nutr. 2013;109:413-24 pubmed 出版商
Dinis J, Silva V, Gromicho M, Martins C, Laires A, Tavares P, et al. DNA damage response in imatinib resistant chronic myeloid leukemia K562 cells. Leuk Lymphoma. 2012;53:2004-14 pubmed 出版商
Schneider S, Carra G, Sahin U, Hoy B, Rieder G, Wessler S. Complex cellular responses of Helicobacter pylori-colonized gastric adenocarcinoma cells. Infect Immun. 2011;79:2362-71 pubmed 出版商
Vilas Zornoza A, Agirre X, Martín Palanco V, Martin Subero J, San Jose Eneriz E, Garate L, et al. Frequent and simultaneous epigenetic inactivation of TP53 pathway genes in acute lymphoblastic leukemia. PLoS ONE. 2011;6:e17012 pubmed 出版商
Khusial P, Vadla B, Krishnan H, Ramlall T, Shen Y, Ichikawa H, et al. Src activates Abl to augment Robo1 expression in order to promote tumor cell migration. Oncotarget. 2010;1:198-209 pubmed
Hanafusa H, Ishikawa K, Kedashiro S, Saigo T, Iemura S, Natsume T, et al. Leucine-rich repeat kinase LRRK1 regulates endosomal trafficking of the EGF receptor. Nat Commun. 2011;2:158 pubmed
Warsch W, Kollmann K, Eckelhart E, Fajmann S, Cerny Reiterer S, Hölbl A, et al. High STAT5 levels mediate imatinib resistance and indicate disease progression in chronic myeloid leukemia. Blood. 2011;117:3409-20 pubmed 出版商
Chen J, Wang M, Hung W. Bcr-Abl-induced tyrosine phosphorylation of Emi1 to stabilize Skp2 protein via inhibition of ubiquitination in chronic myeloid leukemia cells. J Cell Physiol. 2011;226:407-13 pubmed 出版商
Mizutani T, Kondo T, Darmanin S, Tsuda M, Tanaka S, Tobiume M, et al. A novel FRET-based biosensor for the measurement of BCR-ABL activity and its response to drugs in living cells. Clin Cancer Res. 2010;16:3964-75 pubmed 出版商
Zuniga F, Craft C. Deciphering the structure and function of Als2cr4 in the mouse retina. Invest Ophthalmol Vis Sci. 2010;51:4407-15 pubmed 出版商
Takeuchi M, Kimura S, Kuroda J, Ashihara E, Kawatani M, Osada H, et al. Glyoxalase-I is a novel target against Bcr-Abl+ leukemic cells acquiring stem-like characteristics in a hypoxic environment. Cell Death Differ. 2010;17:1211-20 pubmed 出版商
May V, Lutz E, MacKenzie C, Schutz K, Dozark K, Braas K. Pituitary adenylate cyclase-activating polypeptide (PACAP)/PAC1HOP1 receptor activation coordinates multiple neurotrophic signaling pathways: Akt activation through phosphatidylinositol 3-kinase gamma and vesicle endocytosis for neuronal survival. J Biol Chem. 2010;285:9749-61 pubmed 出版商
Fulciniti M, Tassone P, Hideshima T, Vallet S, Nanjappa P, Ettenberg S, et al. Anti-DKK1 mAb (BHQ880) as a potential therapeutic agent for multiple myeloma. Blood. 2009;114:371-9 pubmed 出版商
Qiao F, Gao C, Tripathi B, Zelenka P. Distinct functions of Cdk5(Y15) phosphorylation and Cdk5 activity in stress fiber formation and organization. Exp Cell Res. 2008;314:3542-50 pubmed 出版商
Pielage J, Powell K, Kalman D, Engel J. RNAi screen reveals an Abl kinase-dependent host cell pathway involved in Pseudomonas aeruginosa internalization. PLoS Pathog. 2008;4:e1000031 pubmed 出版商
Williams R, Roussel M, Sherr C. Arf gene loss enhances oncogenicity and limits imatinib response in mouse models of Bcr-Abl-induced acute lymphoblastic leukemia. Proc Natl Acad Sci U S A. 2006;103:6688-93 pubmed
Kurebayashi J, Okubo S, Yamamoto Y, Ikeda M, Tanaka K, Otsuki T, et al. Additive antitumor effects of gefitinib and imatinib on anaplastic thyroid cancer cells. Cancer Chemother Pharmacol. 2006;58:460-70 pubmed
Liu L, D Mello S. Phosphorylation of IkappaB-beta is necessary for neuronal survival. J Biol Chem. 2006;281:1506-15 pubmed
Burchert A, Wang Y, Cai D, von Bubnoff N, Paschka P, Müller Brüsselbach S, et al. Compensatory PI3-kinase/Akt/mTor activation regulates imatinib resistance development. Leukemia. 2005;19:1774-82 pubmed
Simpson L, He X, Pins M, Huang X, Campbell S, Yang X, et al. Renal medullary carcinoma and ABL gene amplification. J Urol. 2005;173:1883-8 pubmed
产品信息
产品名称 :
c-Abl (24-11) Antibody
基因名称 :
ABL1, BCR
规格 :
100微克/毫升
目录号 :
sc-23
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
c-Abl
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 酶联免疫吸附测定
表位 :
C末端
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。