产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
毛细血管扩张性共济失调症突变蛋白(2C1)抗体
目录 :
sc-23921
规格 :
100微克/毫升
价格 :
303美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
2C1
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
文章摘录数: 33
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:1000; 图 1e
Zhang J, Lee Y, Dang F, Gan W, Menon A, Katon J, et al. PTEN Methylation by NSD2 Controls Cellular Sensitivity to DNA Damage. Cancer Discov. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Shin S, Song J, Hwang B, Noh D, Park S, Kim W, et al. HSPA6 augments garlic extract-induced inhibition of proliferation, migration, and invasion of bladder cancer EJ cells; Implication for cell cycle dysregulation, signaling pathway alteration, and transcription factor-associated MMP-9 regulation. PLoS ONE. 2017;12:e0171860 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Ray A, Blevins C, Wani G, Wani A. ATR- and ATM-Mediated DNA Damage Response Is Dependent on Excision Repair Assembly during G1 but Not in S Phase of Cell Cycle. PLoS ONE. 2016;11:e0159344 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Cataldo A, Cheung D, Balsari A, Tagliabue E, Coppola V, Iorio M, et al. miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response. Oncotarget. 2016;7:786-97 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Cristini A, Park J, Capranico G, Legube G, Favre G, Sordet O. DNA-PK triggers histone ubiquitination and signaling in response to DNA double-strand breaks produced during the repair of transcription-blocking topoisomerase I lesions. Nucleic Acids Res. 2016;44:1161-78 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Matsunuma R, Niida H, Ohhata T, Kitagawa K, Sakai S, Uchida C, et al. UV Damage-Induced Phosphorylation of HBO1 Triggers CRL4DDB2-Mediated Degradation To Regulate Cell Proliferation. Mol Cell Biol. 2016;36:394-406 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4e
Kanu N, Zhang T, Burrell R, Chakraborty A, Cronshaw J, DaCosta C, et al. RAD18, WRNIP1 and ATMIN promote ATM signalling in response to replication stress. Oncogene. 2016;35:4009-19 pubmed 出版商
  • 免疫沉淀; 人类; 图 5
  • 免疫印迹; 人类; 1:1000; 图 3
Ortega Atienza S, Wong V, Deloughery Z, Luczak M, Zhitkovich A. ATM and KAT5 safeguard replicating chromatin against formaldehyde damage. Nucleic Acids Res. 2016;44:198-209 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 3d
  • 免疫印迹; 人类; 1:1000; 图 3f
Zhang J, Tripathi D, Jing J, Alexander A, Kim J, Powell R, et al. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015;17:1259-1269 pubmed 出版商
  • 免疫印迹; 小鼠
Xiong J, Todorova D, Su N, Kim J, Lee P, Shen Z, et al. Stemness factor Sall4 is required for DNA damage response in embryonic stem cells. J Cell Biol. 2015;208:513-20 pubmed 出版商
  • 免疫印迹; 人类
Nakahara T, Tanaka K, Ohno S, Egawa N, Yugawa T, Kiyono T. Activation of NF-κB by human papillomavirus 16 E1 limits E1-dependent viral replication through degradation of E1. J Virol. 2015;89:5040-59 pubmed 出版商
  • 免疫印迹; 人类; 图 s7
Ekumi K, Paculova H, Lenasi T, Pospichalova V, Bösken C, Rybarikova J, et al. Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex. Nucleic Acids Res. 2015;43:2575-89 pubmed 出版商
  • 免疫印迹; 人类
Sekimoto T, Oda T, Kurashima K, Hanaoka F, Yamashita T. Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication. Mol Cell Biol. 2015;35:699-715 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7d
Zhang P, Wei Y, Wang L, Debeb B, Yuan Y, Zhang J, et al. ATM-mediated stabilization of ZEB1 promotes DNA damage response and radioresistance through CHK1. Nat Cell Biol. 2014;16:864-75 pubmed 出版商
  • 免疫印迹; 人类
Belanger F, Rajotte V, Drobetsky E. A majority of human melanoma cell lines exhibits an S phase-specific defect in excision of UV-induced DNA photoproducts. PLoS ONE. 2014;9:e85294 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Penicud K, Behrens A. DMAP1 is an essential regulator of ATM activity and function. Oncogene. 2014;33:525-31 pubmed 出版商
Islam M, Takano R, Yokochi T, Akter J, Nakamura Y, Nakagawara A, et al. Programmed expression of pro-apoptotic BMCC1 during apoptosis, triggered by DNA damage in neuroblastoma cells. BMC Cancer. 2019;19:542 pubmed 出版商
Gao R, Chakraborty A, Geater C, Pradhan S, Gordon K, Snowden J, et al. Mutant huntingtin impairs PNKP and ATXN3, disrupting DNA repair and transcription. elife. 2019;8: pubmed 出版商
Stebbing J, Shah K, Lit L, Gagliano T, Ditsiou A, Wang T, et al. LMTK3 confers chemo-resistance in breast cancer. Oncogene. 2018;37:3113-3130 pubmed 出版商
Lesport E, Ferster A, Biver A, Roch B, Vasquez N, Jabado N, et al. Reduced recruitment of 53BP1 during interstrand crosslink repair is associated with genetically inherited attenuation of mitomycin C sensitivity in a family with Fanconi anemia. Oncotarget. 2018;9:3779-3793 pubmed 出版商
Panchakshari R, Zhang X, Kumar V, Du Z, Wei P, Kao J, et al. DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions. Proc Natl Acad Sci U S A. 2018;115:762-767 pubmed 出版商
Exell J, Thompson M, Finger L, Shaw S, Debreczeni J, Ward T, et al. Cellularly active N-hydroxyurea FEN1 inhibitors block substrate entry to the active site. Nat Chem Biol. 2016;12:815-21 pubmed 出版商
Gagou M, Ganesh A, Phear G, Robinson D, Petermann E, Cox A, et al. Human PIF1 helicase supports DNA replication and cell growth under oncogenic-stress. Oncotarget. 2014;5:11381-98 pubmed
Ray A, Milum K, Battu A, Wani G, Wani A. NER initiation factors, DDB2 and XPC, regulate UV radiation response by recruiting ATR and ATM kinases to DNA damage sites. DNA Repair (Amst). 2013;12:273-83 pubmed 出版商
Kim W, Kim J. Deleted in breast cancer 1 (DBC1) deficiency results in apoptosis of breast cancer cells through impaired responses to UV-induced DNA damage. Cancer Lett. 2013;333:180-6 pubmed 出版商
Gaudio E, Spizzo R, Paduano F, Luo Z, Efanov A, Palamarchuk A, et al. Tcl1 interacts with Atm and enhances NF-?B activation in hematologic malignancies. Blood. 2012;119:180-7 pubmed 出版商
Battu A, Ray A, Wani A. ASF1A and ATM regulate H3K56-mediated cell-cycle checkpoint recovery in response to UV irradiation. Nucleic Acids Res. 2011;39:7931-45 pubmed 出版商
Niida H, Katsuno Y, Sengoku M, Shimada M, Yukawa M, Ikura M, et al. Essential role of Tip60-dependent recruitment of ribonucleotide reductase at DNA damage sites in DNA repair during G1 phase. Genes Dev. 2010;24:333-8 pubmed 出版商
Nakayama Y, Igarashi A, Kikuchi I, Obata Y, Fukumoto Y, Yamaguchi N. Bleomycin-induced over-replication involves sustained inhibition of mitotic entry through the ATM/ATR pathway. Exp Cell Res. 2009;315:2515-28 pubmed 出版商
Ji J, Jang Y. Cellular effects of genotoxic stress and gene silencing of the checkpoint kinases in human oral cells. J Oral Pathol Med. 2009;38:591-6 pubmed 出版商
Feng Z, Hu W, Teresky A, Hernando E, Cordon Cardo C, Levine A. Declining p53 function in the aging process: a possible mechanism for the increased tumor incidence in older populations. Proc Natl Acad Sci U S A. 2007;104:16633-8 pubmed
Difilippantonio S, Celeste A, Kruhlak M, Lee Y, Difilippantonio M, Feigenbaum L, et al. Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis. J Exp Med. 2007;204:1003-11 pubmed
Niida H, Tsuge S, Katsuno Y, Konishi A, Takeda N, Nakanishi M. Depletion of Chk1 leads to premature activation of Cdc2-cyclin B and mitotic catastrophe. J Biol Chem. 2005;280:39246-52 pubmed
产品信息
产品名称 :
毛细血管扩张性共济失调症突变蛋白(2C1)抗体
基因名称 :
毛细血管扩张性共济失调症突变蛋白
规格 :
100微克/毫升
价格 :
303美元
目录号 :
sc-23921
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
毛细血管扩张性共济失调症突变蛋白
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF
表位 :
2577-3056(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。