产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
α微管蛋白(B-5-1-2)抗体
目录 :
sc-23948
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
B-5-1-2
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 82
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 s3a
Yang S, Harding A, Sweeney C, Miao D, Swan G, Zhou C, et al. Control of antiviral innate immune response by protein geranylgeranylation. Sci Adv. 2019;5:eaav7999 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s4b
Bugaj L, Sabnis A, Mitchell A, Garbarino J, Toettcher J, Bivona T, et al. Cancer mutations and targeted drugs can disrupt dynamic signal encoding by the Ras-Erk pathway. Science. 2018;361: pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Zhao H, Klausen C, Li Y, Zhu H, Wang Y, Leung P. Bone morphogenetic protein 2 promotes human trophoblast cell invasion by upregulating N-cadherin via non-canonical SMAD2/3 signaling. Cell Death Dis. 2018;9:174 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Guo L, Costanzo Garvey D, Smith D, Zavorka M, Venable Kang M, MacDonald R, et al. Cell non-autonomous regulation of hepatic IGF-1 and neonatal growth by Kinase Suppressor of Ras 2 (KSR2). Sci Rep. 2016;6:32093 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3a
Park Y, Nam H, Do M, Lee J. The p90 ribosomal S6 kinase 2 specifically affects mitotic progression by regulating the basal level, distribution and stability of mitotic spindles. Exp Mol Med. 2016;48:e250 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s1
  • 免疫印迹; 人类; 1:1000; 图 s3
Wang J, Farris A, Xu K, Wang P, Zhang X, Duong D, et al. GPRC5A suppresses protein synthesis at the endoplasmic reticulum to prevent radiation-induced lung tumorigenesis. Nat Commun. 2016;7:11795 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Lim S, Liu H, Madeira da Silva L, Arora R, Liu Z, Phillips J, et al. Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1?. Cancer Res. 2016;76:2231-42 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Alquezar C, Salado I, de la Encarnación A, Perez D, Moreno F, Gil C, et al. Targeting TDP-43 phosphorylation by Casein Kinase-1? inhibitors: a novel strategy for the treatment of frontotemporal dementia. Mol Neurodegener. 2016;11:36 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Tanaka T, Takei Y, Yamanouchi D. Hyperglycemia Suppresses Calcium Phosphate-Induced Aneurysm Formation Through Inhibition of Macrophage Activation. J Am Heart Assoc. 2016;5:e003062 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1
de Lange J, Faramarz A, Oostra A, de Menezes R, van der Meulen I, Rooimans M, et al. Defective sister chromatid cohesion is synthetically lethal with impaired APC/C function. Nat Commun. 2015;6:8399 pubmed 出版商
  • 免疫细胞化学; 人类; 1:650; 图 2b
Lüddecke S, Ertych N, Stenzinger A, Weichert W, Beissbarth T, Dyczkowski J, et al. The putative oncogene CEP72 inhibits the mitotic function of BRCA1 and induces chromosomal instability. Oncogene. 2016;35:2398-406 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6d
Mohankumar K, Currle D, White E, Boulos N, Dapper J, Eden C, et al. An in vivo screen identifies ependymoma oncogenes and tumor-suppressor genes. Nat Genet. 2015;47:878-87 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Gagnon J, Daou S, Zamorano N, Iannantuono N, Hammond Martel I, Mashtalir N, et al. Undetectable histone O-GlcNAcylation in mammalian cells. Epigenetics. 2015;10:677-91 pubmed 出版商
  • 免疫印迹; 人类
Park S, Choi S, Yoo S, Nah J, Jeong E, Kim H, et al. Pyruvate stimulates mitophagy via PINK1 stabilization. Cell Signal. 2015;27:1824-30 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7
  • 免疫印迹; 人类; 图 1
Li S, Oh Y, Yue P, Khuri F, Sun S. Inhibition of mTOR complex 2 induces GSK3/FBXW7-dependent degradation of sterol regulatory element-binding protein 1 (SREBP1) and suppresses lipogenesis in cancer cells. Oncogene. 2016;35:642-50 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Wijeweera A, Haj M, Feldman A, Pnueli L, Luo Z, Melamed P. Gonadotropin gene transcription is activated by menin-mediated effects on the chromatin. Biochim Biophys Acta. 2015;1849:328-41 pubmed 出版商
  • 免疫细胞化学; 人类; 1:700; 图 3
Stolz A, Ertych N, Bastians H. A phenotypic screen identifies microtubule plus end assembly regulators that can function in mitotic spindle orientation. Cell Cycle. 2015;14:827-37 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 1
Sathyamurthy A, Yin D, Barik A, Shen C, Bean J, Figueiredo D, et al. ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination. Development. 2015;142:522-32 pubmed 出版商
  • 免疫印迹; 人类
Peng H, Kaplan N, Yang W, Getsios S, Lavker R. FIH-1 disrupts an LRRK1/EGFR complex to positively regulate keratinocyte migration. Am J Pathol. 2014;184:3262-71 pubmed 出版商
  • 免疫印迹; 人类
Tun A, Chaiyarit S, Kaewsutthi S, Katanyoo W, Chuenkongkaew W, Kuwano M, et al. Profiling the mitochondrial proteome of Leber's Hereditary Optic Neuropathy (LHON) in Thailand: down-regulation of bioenergetics and mitochondrial protein quality control pathways in fibroblasts with the 11778G>A mutation. PLoS ONE. 2014;9:e106779 pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 2c
Zha Y, Xia Y, Ding J, Choi J, Yang L, Dong Z, et al. MEIS2 is essential for neuroblastoma cell survival and proliferation by transcriptional control of M-phase progression. Cell Death Dis. 2014;5:e1417 pubmed 出版商
  • 免疫印迹; 人类
Kelso T, Baumgart K, Eickhoff J, Albert T, Antrecht C, Lemcke S, et al. Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells. Mol Cell Biol. 2014;34:3675-88 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Duitman J, Ruela de Sousa R, Shi K, de Boer O, Borensztajn K, Florquin S, et al. Protease activated receptor-1 deficiency diminishes bleomycin-induced skin fibrosis. Mol Med. 2014;20:410-6 pubmed 出版商
Zhao Y, Zhou J, He L, Li Y, Yuan J, Sun K, et al. MyoD induced enhancer RNA interacts with hnRNPL to activate target gene transcription during myogenic differentiation. Nat Commun. 2019;10:5787 pubmed 出版商
Hayashi Y, Goyama S, Liu X, Tamura M, Asada S, Tanaka Y, et al. Antitumor immunity augments the therapeutic effects of p53 activation on acute myeloid leukemia. Nat Commun. 2019;10:4869 pubmed 出版商
Zhou J, So K, Li Y, Li Y, Yuan J, Ding Y, et al. Elevated H3K27ac in aged skeletal muscle leads to increase in extracellular matrix and fibrogenic conversion of muscle satellite cells. Aging Cell. 2019;18:e12996 pubmed 出版商
Do H, Kim D, Kang J, Son B, Seo D, Youn H, et al. TFAP2C increases cell proliferation by downregulating GADD45B and PMAIP1 in non-small cell lung cancer cells. Biol Res. 2019;52:35 pubmed 出版商
Pattschull G, Walz S, Gründl M, Schwab M, Rühl E, Baluapuri A, et al. The Myb-MuvB Complex Is Required for YAP-Dependent Transcription of Mitotic Genes. Cell Rep. 2019;27:3533-3546.e7 pubmed 出版商
Ahn J, Cho M, Sohn S, Lee J. Inhibition of PP2A activity by H2O2 during mitosis disrupts nuclear envelope reassembly and alters nuclear shape. Exp Mol Med. 2019;51:64 pubmed 出版商
Steurer B, Turkyilmaz Y, van Toorn M, van Leeuwen W, Escudero Ferruz P, Marteijn J. Fluorescently-labelled CPD and 6-4PP photolyases: new tools for live-cell DNA damage quantification and laser-assisted repair. Nucleic Acids Res. 2019;47:3536-3549 pubmed 出版商
Bailey C, Metierre C, Feng Y, Baidya K, Filippova G, Loukinov D, et al. CTCF Expression is Essential for Somatic Cell Viability and Protection Against Cancer. Int J Mol Sci. 2018;19: pubmed 出版商
Wang L, Niu N, Li L, Shao R, Ouyang H, Zou W. H3K36 trimethylation mediated by SETD2 regulates the fate of bone marrow mesenchymal stem cells. PLoS Biol. 2018;16:e2006522 pubmed 出版商
Essig K, Kronbeck N, Guimaraes J, Lohs C, Schlundt A, Hoffmann A, et al. Roquin targets mRNAs in a 3'-UTR-specific manner by different modes of regulation. Nat Commun. 2018;9:3810 pubmed 出版商
Bagchi R, Ferguson B, Stratton M, Hu T, Cavasin M, Sun L, et al. HDAC11 suppresses the thermogenic program of adipose tissue via BRD2. JCI Insight. 2018;3: pubmed 出版商
Romanick S, Ulrich C, Schlauch K, Hostler A, Payne J, Woolsey R, et al. Obesity-mediated regulation of cardiac protein acetylation: parallel analysis of total and acetylated proteins via TMT-tagged mass spectrometry. Biosci Rep. 2018;38: pubmed 出版商
Zhang H, Tian J, Qi X, Xiang T, He G, Zhang H, et al. Epstein-Barr virus activates F-box protein FBXO2 to limit viral infectivity by targeting glycoprotein B for degradation. PLoS Pathog. 2018;14:e1007208 pubmed 出版商
Sun J, Ermann J, Niu N, Yan G, Yang Y, Shi Y, et al. Histone demethylase LSD1 regulates bone mass by controlling WNT7B and BMP2 signaling in osteoblasts. Bone Res. 2018;6:14 pubmed 出版商
Li H, Chang H, Shi Z, Leung P. SNAIL Mediates TGF-β1-Induced Downregulation of Pentraxin 3 Expression in Human Granulosa Cells. Endocrinology. 2018;159:1644-1657 pubmed 出版商
Wang Y, Liu X, Zhou L, Duong D, Bhuripanyo K, Zhao B, et al. Identifying the ubiquitination targets of E6AP by orthogonal ubiquitin transfer. Nat Commun. 2017;8:2232 pubmed 出版商
Oldrini B, Hsieh W, Erdjument Bromage H, Codega P, Carro M, Curiel García A, et al. EGFR feedback-inhibition by Ran-binding protein 6 is disrupted in cancer. Nat Commun. 2017;8:2035 pubmed 出版商
Li Z, Li M, Wood K, Hettwer S, Muley S, Shi F, et al. Engineered Agrin Attenuates the Severity of Experimental Autoimmune Myasthenia Gravis. Muscle Nerve. 2017;: pubmed 出版商
Moreno N, Holsten T, Mertins J, Zhogbi A, Johann P, Kool M, et al. Combined BRD4 and CDK9 inhibition as a new therapeutic approach in malignant rhabdoid tumors. Oncotarget. 2017;8:84986-84995 pubmed 出版商
Kim J, Kim H, Yu D, Kweon H, Huh Y, Kim H. Changes in numbers and size of synaptic vesicles of cortical neurons induced by exposure to 835 MHz radiofrequency-electromagnetic field. PLoS ONE. 2017;12:e0186416 pubmed 出版商
Gorbea C, Mosbruger T, Cazalla D. A viral Sm-class RNA base-pairs with mRNAs and recruits microRNAs to inhibit apoptosis. Nature. 2017;550:275-279 pubmed 出版商
Vergara D, Stanca E, Guerra F, Priore P, Gaballo A, Franck J, et al. ?-Catenin Knockdown Affects Mitochondrial Biogenesis and Lipid Metabolism in Breast Cancer Cells. Front Physiol. 2017;8:544 pubmed 出版商
Chapat C, Chettab K, Simonet P, Wang P, de la Grange P, Le Romancer M, et al. Alternative splicing of CNOT7 diversifies CCR4-NOT functions. Nucleic Acids Res. 2017;45:8508-8523 pubmed 出版商
Chapat C, Jafarnejad S, Matta Camacho E, Hesketh G, Gelbart I, Attig J, et al. Cap-binding protein 4EHP effects translation silencing by microRNAs. Proc Natl Acad Sci U S A. 2017;114:5425-5430 pubmed 出版商
Xiang Y, Laurent B, Hsu C, Nachtergaele S, Lu Z, Sheng W, et al. RNA m6A methylation regulates the ultraviolet-induced DNA damage response. Nature. 2017;543:573-576 pubmed 出版商
Xu Z, Greenblatt M, Yan G, Feng H, Sun J, Lotinun S, et al. SMURF2 regulates bone homeostasis by disrupting SMAD3 interaction with vitamin D receptor in osteoblasts. Nat Commun. 2017;8:14570 pubmed 出版商
Wang Y, Pan Q, Ding S, Wang Z, Yu J, Finzi A, et al. The V3 Loop of HIV-1 Env Determines Viral Susceptibility to IFITM3 Impairment of Viral Infectivity. J Virol. 2017;91: pubmed 出版商
O Flanagan C, O Shea S, Lyons A, Fogarty F, McCabe N, Kennedy R, et al. IGF-1R inhibition sensitizes breast cancer cells to ATM-related kinase (ATR) inhibitor and cisplatin. Oncotarget. 2016;7:56826-56841 pubmed 出版商
Alquézar C, de la Encarnación A, Moreno F, López de Munain A, Martín Requero Ã. Progranulin deficiency induces overactivation of WNT5A expression via TNF-α/NF-κB pathway in peripheral cells from frontotemporal dementia-linked granulin mutation carriers. J Psychiatry Neurosci. 2016;41:225-39 pubmed
Lowe D, Raj K. Premature aging induced by radiation exhibits pro-atherosclerotic effects mediated by epigenetic activation of CD44 expression. Aging Cell. 2014;13:900-10 pubmed 出版商
Farhat M, Poissonnier A, Hamze A, Ouk Martin C, Brion J, Alami M, et al. Reversion of apoptotic resistance of TP53-mutated Burkitt lymphoma B-cells to spindle poisons by exogenous activation of JNK and p38 MAP kinases. Cell Death Dis. 2014;5:e1201 pubmed 出版商
Kupershmit I, Khoury Haddad H, Awwad S, Guttmann Raviv N, Ayoub N. KDM4C (GASC1) lysine demethylase is associated with mitotic chromatin and regulates chromosome segregation during mitosis. Nucleic Acids Res. 2014;42:6168-82 pubmed 出版商
Wu G, Diaz A, Paugh B, Rankin S, Ju B, Li Y, et al. The genomic landscape of diffuse intrinsic pontine glioma and pediatric non-brainstem high-grade glioma. Nat Genet. 2014;46:444-450 pubmed 出版商
Brzoska K, Stępkowski T, Kruszewski M. Basal PIR expression in HeLa cells is driven by NRF2 via evolutionary conserved antioxidant response element. Mol Cell Biochem. 2014;389:99-111 pubmed 出版商
Seo Y, Pritzl C, Vijayan M, Bomb K, McClain M, Alexander S, et al. Sphingosine kinase 1 serves as a pro-viral factor by regulating viral RNA synthesis and nuclear export of viral ribonucleoprotein complex upon influenza virus infection. PLoS ONE. 2013;8:e75005 pubmed 出版商
Paugh B, Zhu X, Qu C, Endersby R, Diaz A, Zhang J, et al. Novel oncogenic PDGFRA mutations in pediatric high-grade gliomas. Cancer Res. 2013;73:6219-29 pubmed 出版商
Kim M, Kim H, Yoon S, Lim S, Cha M, Jeon Y, et al. Colon cancer progression is driven by APEX1-mediated upregulation of Jagged. J Clin Invest. 2013;: pubmed 出版商
Kerl K, Ries D, Unland R, Borchert C, Moreno N, Hasselblatt M, et al. The histone deacetylase inhibitor SAHA acts in synergism with fenretinide and doxorubicin to control growth of rhabdoid tumor cells. BMC Cancer. 2013;13:286 pubmed 出版商
Halbach S, Rigbolt K, Wöhrle F, Diedrich B, Gretzmeier C, Brummer T, et al. Alterations of Gab2 signalling complexes in imatinib and dasatinib treated chronic myeloid leukaemia cells. Cell Commun Signal. 2013;11:30 pubmed 出版商
Lee Y, Chung S, Baek I, Lee T, Paik S, Lee J. UNC119a bridges the transmission of Fyn signals to Rab11, leading to the completion of cytokinesis. Cell Cycle. 2013;12:1303-15 pubmed 出版商
Wu L, Hu M, Tong X, Han H, Shen N, Jin R, et al. Chronic unpredictable stress decreases expression of brain-derived neurotrophic factor (BDNF) in mouse ovaries: relationship to oocytes developmental potential. PLoS ONE. 2012;7:e52331 pubmed 出版商
Kreutmayer S, Csordas A, Kern J, Maass V, Almanzar G, Offterdinger M, et al. Chlamydia pneumoniae infection acts as an endothelial stressor with the potential to initiate the earliest heat shock protein 60-dependent inflammatory stage of atherosclerosis. Cell Stress Chaperones. 2013;18:259-68 pubmed 出版商
Cheng Y, Ren X, Zhang Y, Shan Y, Huber Keener K, Zhang L, et al. Integrated regulation of autophagy and apoptosis by EEF2K controls cellular fate and modulates the efficacy of curcumin and velcade against tumor cells. Autophagy. 2013;9:208-19 pubmed 出版商
Esteras N, Alquezar C, Bermejo Pareja F, Bialopiotrowicz E, Wojda U, Martin Requero A. Downregulation of extracellular signal-regulated kinase 1/2 activity by calmodulin KII modulates p21Cip1 levels and survival of immortalized lymphocytes from Alzheimer's disease patients. Neurobiol Aging. 2013;34:1090-100 pubmed 出版商
Woellmer A, Arteaga Salas J, Hammerschmidt W. BZLF1 governs CpG-methylated chromatin of Epstein-Barr Virus reversing epigenetic repression. PLoS Pathog. 2012;8:e1002902 pubmed 出版商
Wu H, Lu Y, Barik A, Joseph A, Taketo M, Xiong W, et al. ?-Catenin gain of function in muscles impairs neuromuscular junction formation. Development. 2012;139:2392-404 pubmed 出版商
Chan S, Li Y, Dehm S. Androgen receptor splice variants activate androgen receptor target genes and support aberrant prostate cancer cell growth independent of canonical androgen receptor nuclear localization signal. J Biol Chem. 2012;287:19736-49 pubmed 出版商
Sharma A, Yilmaz A, Marsh K, Cochrane A, Boris Lawrie K. Thriving under stress: selective translation of HIV-1 structural protein mRNA during Vpr-mediated impairment of eIF4E translation activity. PLoS Pathog. 2012;8:e1002612 pubmed 出版商
Rolf H, Niebert S, Niebert M, Gaus L, Schliephake H, Wiese K. Intercellular transport of Oct4 in mammalian cells: a basic principle to expand a stem cell niche?. PLoS ONE. 2012;7:e32287 pubmed 出版商
Canino C, Mori F, Cambria A, Diamantini A, Germoni S, Alessandrini G, et al. SASP mediates chemoresistance and tumor-initiating-activity of mesothelioma cells. Oncogene. 2012;31:3148-63 pubmed 出版商
Zheng Z, Li L, Liu X, Wang D, Tu B, Wang L, et al. 5-Aza-2'-deoxycytidine reactivates gene expression via degradation of pRb pocket proteins. FASEB J. 2012;26:449-59 pubmed 出版商
Chen J, Tsu C, Gavin J, Milhollen M, Bruzzese F, Mallender W, et al. Mechanistic studies of substrate-assisted inhibition of ubiquitin-activating enzyme by adenosine sulfamate analogues. J Biol Chem. 2011;286:40867-77 pubmed 出版商
Khromova N, Kopnin P, Rybko V, Kopnin B. Downregulation of VEGF-C expression in lung and colon cancer cells decelerates tumor growth and inhibits metastasis via multiple mechanisms. Oncogene. 2012;31:1389-97 pubmed 出版商
Audry M, Ciancanelli M, Yang K, Cobat A, Chang H, Sancho Shimizu V, et al. NEMO is a key component of NF-?B- and IRF-3-dependent TLR3-mediated immunity to herpes simplex virus. J Allergy Clin Immunol. 2011;128:610-7.e1-4 pubmed 出版商
Chang C, Chen S, Lee T, Lee H, Chen S, Shyue S. Caveolin-1 deletion reduces early brain injury after experimental intracerebral hemorrhage. Am J Pathol. 2011;178:1749-61 pubmed 出版商
Wu C, Li T, Hsu S, Su Y, Kao S, Fong Y, et al. IGF-I enhances ?5?1 integrin expression and cell motility in human chondrosarcoma cells. J Cell Physiol. 2011;226:3270-7 pubmed 出版商
Thepparit C, Bourchookarn A, Petchampai N, Barker S, Macaluso K. Interaction of Rickettsia felis with histone H2B facilitates the infection of a tick cell line. Microbiology. 2010;156:2855-63 pubmed 出版商
Bui T, Sequeira J, Wen T, Sola A, Higashi Y, Kondoh H, et al. ZEB1 links p63 and p73 in a novel neuronal survival pathway rapidly induced in response to cortical ischemia. PLoS ONE. 2009;4:e4373 pubmed 出版商
Pessina A, Bonomi A, Casati S, Collotta A, Croera C, Marafante E, et al. Mitochondrial function, apoptosis and cell cycle delay in the WEHI-3B leukaemia cell line and its variant Ciprofloxacin-resistant WEHI-3B/CPX. Cell Prolif. 2007;40:568-79 pubmed
产品信息
产品名称 :
α微管蛋白(B-5-1-2)抗体
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-23948
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
α微管蛋白
反应物种 :
多个物种
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P)
表位 :
FL(海胆)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。