产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
磷酸甘油醛脱氢酶(FL-335)
目录 :
sc-25778
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, 斑马鱼
应用 :
免疫印迹, 免疫组化
更多信息或购买 :
文章摘录数: 271
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 1:500; 图 3b
  • 免疫印迹; 小鼠; 1:500; 图 3b
Martínez González L, Rodríguez Cueto C, Cabezudo D, Bartolomé F, Andrés Benito P, Ferrer I, et al. Motor neuron preservation and decrease of in vivo TDP-43 phosphorylation by protein CK-1δ kinase inhibitor treatment. Sci Rep. 2020;10:4449 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Nakai A, Fujimoto J, Miyata H, Stumm R, Narazaki M, Schulz S, et al. The COMMD3/8 complex determines GRK6 specificity for chemoattractant receptors. J Exp Med. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 图 1f
Rausch V, Bostrom J, Park J, Bravo I, Feng Y, Hay D, et al. The Hippo Pathway Regulates Caveolae Expression and Mediates Flow Response via Caveolae. Curr Biol. 2019;29:242-255.e6 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Urtishak K, Wang L, Culjkovic Kraljacic B, Davenport J, Porazzi P, Vincent T, et al. Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia. Oncogene. 2019;38:2241-2262 pubmed 出版商
  • 免疫印迹; 斑马鱼; 1:1000; 图 ex1m
Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Kralovicova J, Sevcikova I, Stejskalova E, Obuca M, Hiller M, Stanek D, et al. PUF60-activated exons uncover altered 3' splice-site selection by germline missense mutations in a single RRM. Nucleic Acids Res. 2018;46:6166-6187 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3d
Parikh V, Liu J, Shang C, Woods C, Chang A, Zhao M, et al. Apelin and APJ orchestrate complex tissue-specific control of cardiomyocyte hypertrophy and contractility in the hypertrophy-heart failure transition. Am J Physiol Heart Circ Physiol. 2018;315:H348-H356 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
François C, Petit F, Giton F, Gougeon A, Ravel C, Magre S, et al. A novel action of follicle-stimulating hormone in the ovary promotes estradiol production without inducing excessive follicular growth before puberty. Sci Rep. 2017;7:46222 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 1
Wizeman J, Nicholas A, Ishigami A, Mohan R. Citrullination of glial intermediate filaments is an early response in retinal injury. Mol Vis. 2016;22:1137-1155 pubmed
  • 免疫印迹; 人类; 图 1
Weikel K, Cacicedo J, Ruderman N, Ido Y. Knockdown of GSK3β increases basal autophagy and AMPK signalling in nutrient-laden human aortic endothelial cells. Biosci Rep. 2016;36: pubmed 出版商
  • 免疫印迹; 人类; 图 5
Kim H, Choi M, Inn K, Kim B. Inhibition of HIV-1 reactivation by a telomerase-derived peptide in a HSP90-dependent manner. Sci Rep. 2016;6:28896 pubmed 出版商
  • 免疫印迹; 人类; 图 s2
Tobita T, Guzman Lepe J, Takeishi K, Nakao T, Wang Y, Meng F, et al. SIRT1 Disruption in Human Fetal Hepatocytes Leads to Increased Accumulation of Glucose and Lipids. PLoS ONE. 2016;11:e0149344 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Preet R, Siddharth S, Satapathy S, Das S, Nayak A, Das D, et al. Chk1 inhibitor synergizes quinacrine mediated apoptosis in breast cancer cells by compromising the base excision repair cascade. Biochem Pharmacol. 2016;105:23-33 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Wang B, Ma A, Zhang L, Jin W, Qian Y, Xu G, et al. POH1 deubiquitylates and stabilizes E2F1 to promote tumour formation. Nat Commun. 2015;6:8704 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1500; 图 4
Boczek T, Lisek M, Ferenc B, Wiktorska M, Ivchevska I, Zylinska L. Region-specific effects of repeated ketamine administration on the presynaptic GABAergic neurochemistry in rat brain. Neurochem Int. 2015;91:13-25 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Qin J, Zhou Z, Chen W, Wang C, Zhang H, Ge G, et al. BAP1 promotes breast cancer cell proliferation and metastasis by deubiquitinating KLF5. Nat Commun. 2015;6:8471 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 3f
  • 免疫印迹; 大鼠; 1:5000; 图 3d
Zhang J, Tripathi D, Jing J, Alexander A, Kim J, Powell R, et al. ATM functions at the peroxisome to induce pexophagy in response to ROS. Nat Cell Biol. 2015;17:1259-1269 pubmed 出版商
  • 免疫印迹; 人类; 1:4000; 图 1
Chung H, Jacobs C, Huo Y, Yang J, Krumm S, Plemper R, et al. Tunable and reversible drug control of protein production via a self-excising degron. Nat Chem Biol. 2015;11:713-20 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 4
Hedberg Oldfors C, Dios D, Linder A, Visuttijai K, Samuelson E, Karlsson S, et al. Analysis of an independent tumor suppressor locus telomeric to Tp53 suggested Inpp5k and Myo1c as novel tumor suppressor gene candidates in this region. BMC Genet. 2015;16:80 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Bangs F, Schrode N, Hadjantonakis A, Anderson K. Lineage specificity of primary cilia in the mouse embryo. Nat Cell Biol. 2015;17:113-22 pubmed 出版商
Strah N, Romano G, Introna C, Klima R, Marzullo M, Ciapponi L, et al. TDP-43 promotes the formation of neuromuscular synapses through the regulation of Disc-large expression in Drosophila skeletal muscles. BMC Biol. 2020;18:34 pubmed 出版商
Chen Z, Zhong H, Wei J, Lin S, Zong Z, Gong F, et al. Inhibition of Nrf2/HO-1 signaling leads to increased activation of the NLRP3 inflammasome in osteoarthritis. Arthritis Res Ther. 2019;21:300 pubmed 出版商
Carter R, Milani M, Butterworth M, Alotibi A, Harper N, Yedida G, et al. Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck. Cell Death Dis. 2019;10:912 pubmed 出版商
Chung J, Kim K, An S, Lee S, Lim B, Kang S, et al. Coxsackievirus and adenovirus receptor mediates the responses of endothelial cells to fluid shear stress. Exp Mol Med. 2019;51:144 pubmed 出版商
Guo R, Kim S, Choi C, Na C, Kang B, Kim Y. Inhibitory effects of ChondroT and its constituent herbs on RANKL-induced osteoclastogenesis. BMC Complement Altern Med. 2019;19:319 pubmed 出版商
Carper M, Troutman S, Wagner B, Byrd K, Selitsky S, Parag Sharma K, et al. An Immunocompetent Mouse Model of HPV16(+) Head and Neck Squamous Cell Carcinoma. Cell Rep. 2019;29:1660-1674.e7 pubmed 出版商
Semaan L, Mander N, Cher M, Chinni S. TMPRSS2-ERG fusions confer efficacy of enzalutamide in an in vivo bone tumor growth model. BMC Cancer. 2019;19:972 pubmed 出版商
Barbero G, Castro M, Villanueva M, Quezada M, Fernández N, Demorrow S, et al. An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma. Cells. 2019;8: pubmed 出版商
Yu X, Zhang Y, Wu B, Kurie J, Pertsemlidis A. The miR-195 Axis Regulates Chemoresistance through TUBB and Lung Cancer Progression through BIRC5. Mol Ther Oncolytics. 2019;14:288-298 pubmed 出版商
Gary C, Lam S, Herard A, Koch J, Petit F, Gipchtein P, et al. Encephalopathy induced by Alzheimer brain inoculation in a non-human primate. Acta Neuropathol Commun. 2019;7:126 pubmed 出版商
Corkins M, Krneta Stankic V, Kloc M, McCrea P, Gladden A, Miller R. Divergent roles of the Wnt/PCP Formin Daam1 in renal ciliogenesis. PLoS ONE. 2019;14:e0221698 pubmed 出版商
Bordignon P, Bottoni G, Xu X, Popescu A, Truan Z, Guenova E, et al. Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant. Cell Rep. 2019;28:2358-2372.e6 pubmed 出版商
Parvin S, Ramírez Labrada A, Aumann S, Lu X, Weich N, Santiago G, et al. LMO2 Confers Synthetic Lethality to PARP Inhibition in DLBCL. Cancer Cell. 2019;36:237-249.e6 pubmed 出版商
Pacini V, Petit F, Querat B, Laverrière J, Cohen Tannoudji J, L hôte D. Identification of a pituitary ERα-activated enhancer triggering the expression of Nr5a1, the earliest gonadotrope lineage-specific transcription factor. Epigenetics Chromatin. 2019;12:48 pubmed 出版商
Deng L, Ren R, Liu Z, Song M, Li J, Wu Z, et al. Stabilizing heterochromatin by DGCR8 alleviates senescence and osteoarthritis. Nat Commun. 2019;10:3329 pubmed 出版商
Ding K, Ji J, Zhang X, Huang B, Chen A, Zhang D, et al. RNA splicing factor USP39 promotes glioma progression by inducing TAZ mRNA maturation. Oncogene. 2019;38:6414-6428 pubmed 出版商
Park H, Yu D, Sung M, Oh E, Kim M, Song J, et al. Molecular changes in solitary fibrous tumor progression. J Mol Med (Berl). 2019;97:1413-1425 pubmed 出版商
Zhu C, Li L, Zhang Z, Bi M, Wang H, Su W, et al. A Non-canonical Role of YAP/TEAD Is Required for Activation of Estrogen-Regulated Enhancers in Breast Cancer. Mol Cell. 2019;75:791-806.e8 pubmed 出版商
Reimer M, Pulakanti K, Shi L, Abel A, Liang M, Malarkannan S, et al. Deletion of Tet proteins results in quantitative disparities during ESC differentiation partially attributable to alterations in gene expression. BMC Dev Biol. 2019;19:16 pubmed 出版商
Kaur S, Nag A, Gangenahalli G, Sharma K. Peroxisome Proliferator Activated Receptor Gamma Sensitizes Non-small Cell Lung Carcinoma to Gamma Irradiation Induced Apoptosis. Front Genet. 2019;10:554 pubmed 出版商
Huang H, Kong W, Jean M, Fiches G, Zhou D, Hayashi T, et al. A CRISPR/Cas9 screen identifies the histone demethylase MINA53 as a novel HIV-1 latency-promoting gene (LPG). Nucleic Acids Res. 2019;: pubmed 出版商
Torrini C, Cubero R, Dirkx E, Braga L, Ali H, Prosdocimo G, et al. Common Regulatory Pathways Mediate Activity of MicroRNAs Inducing Cardiomyocyte Proliferation. Cell Rep. 2019;27:2759-2771.e5 pubmed 出版商
Zhang N, Heruth D, Wu W, Zhang L, Nsumu M, Shortt K, et al. Functional characterization of SLC26A3 c.392C>G (p.P131R) mutation in intestinal barrier function using CRISPR/CAS9-created cell models. Cell Biosci. 2019;9:40 pubmed 出版商
Cho E, Jung W, Joo H, Park E, Kim M, Kim S, et al. Cluh plays a pivotal role during adipogenesis by regulating the activity of mitochondria. Sci Rep. 2019;9:6820 pubmed 出版商
Lee Y, Lahens N, Zhang S, Bedont J, FIELD J, Sehgal A. G1/S cell cycle regulators mediate effects of circadian dysregulation on tumor growth and provide targets for timed anticancer treatment. PLoS Biol. 2019;17:e3000228 pubmed 出版商
Lewis R, Li Y, Hoffman L, Hashizume R, Gravohac G, Rice G, et al. Global Reduction of H3K4me3 Improves Chemotherapeutic Efficacy for Pediatric Ependymomas. Neoplasia. 2019;21:505-515 pubmed 出版商
Higuchi T, Takagi K, Tochimoto A, Ichimura Y, Norose T, Katsumata Y, et al. Antifibrotic effects of 2-carba cyclic phosphatidic acid (2ccPA) in systemic sclerosis: contribution to the novel treatment. Arthritis Res Ther. 2019;21:103 pubmed 出版商
Chen L, Toke N, Luo S, Vasoya R, Fullem R, Parthasarathy A, et al. A reinforcing HNF4-SMAD4 feed-forward module stabilizes enterocyte identity. Nat Genet. 2019;51:777-785 pubmed 出版商
Sakaguchi M, Cai W, Wang C, Cederquist C, Damasio M, Homan E, et al. FoxK1 and FoxK2 in insulin regulation of cellular and mitochondrial metabolism. Nat Commun. 2019;10:1582 pubmed 出版商
Poggio M, Hu T, Pai C, Chu B, BELAIR C, Chang A, et al. Suppression of Exosomal PD-L1 Induces Systemic Anti-tumor Immunity and Memory. Cell. 2019;177:414-427.e13 pubmed 出版商
Scavello F, Zeni F, Tedesco C, Mensà E, Veglia F, Procopio A, et al. Modulation of soluble receptor for advanced glycation end-products (RAGE) isoforms and their ligands in healthy aging. Aging (Albany NY). 2019;11:1648-1663 pubmed 出版商
Li H, Petersen S, García Mariscal A, Brakebusch C. Negative Regulation of p53-Induced Senescence by N-WASP Is Crucial for DMBA/TPA-Induced Skin Tumor Formation. Cancer Res. 2019;79:2167-2181 pubmed 出版商
Arceci A, Bonacci T, Wang X, Stewart K, Damrauer J, Hoadley K, et al. FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer. Cell Rep. 2019;26:3076-3086.e6 pubmed 出版商
Pabon N, Zhang Q, Cruz J, Schipper D, Camacho C, Lee R. A network-centric approach to drugging TNF-induced NF-κB signaling. Nat Commun. 2019;10:860 pubmed 出版商
Chang H, Cho S, Lee J, Lee E, Seo J, Lee H, et al. Hypomorphic Mutations in TONSL Cause SPONASTRIME Dysplasia. Am J Hum Genet. 2019;104:439-453 pubmed 出版商
Li Y, Jiang X, Zhang Y, Gao Z, Liu Y, Hu J, et al. Nuclear accumulation of UBC9 contributes to SUMOylation of lamin A/C and nucleophagy in response to DNA damage. J Exp Clin Cancer Res. 2019;38:67 pubmed 出版商
Shortt K, Heruth D, Zhang N, Wu W, Singh S, Li D, et al. Identification of Novel Regulatory Genes in APAP Induced Hepatocyte Toxicity by a Genome-Wide CRISPR-Cas9 Screen. Sci Rep. 2019;9:1396 pubmed 出版商
Mengwasser K, Adeyemi R, Leng Y, Choi M, Clairmont C, D Andrea A, et al. Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets. Mol Cell. 2019;73:885-899.e6 pubmed 出版商
Alameda J, Ramirez A, Garcia Fernandez R, Navarro M, Page A, Segovia J, et al. Premature aging and cancer development in transgenic mice lacking functional CYLD. Aging (Albany NY). 2019;11:127-159 pubmed 出版商
Narayana Y, Gadgil C, Mote R, Rajan R, Subramanyam D. Clathrin-Mediated Endocytosis Regulates a Balance between Opposing Signals to Maintain the Pluripotent State of Embryonic Stem Cells. Stem Cell Reports. 2019;12:152-164 pubmed 出版商
Hatzi K, Geng H, Doane A, Meydan C, LaRiviere R, Cárdenas M, et al. Histone demethylase LSD1 is required for germinal center formation and BCL6-driven lymphomagenesis. Nat Immunol. 2019;20:86-96 pubmed 出版商
Chen L, Pastorino F, Berry P, Bonner J, Kirk C, Wood K, et al. Preclinical evaluation of the first intravenous small molecule MDM2 antagonist alone and in combination with temozolomide in neuroblastoma. Int J Cancer. 2019;144:3146-3159 pubmed 出版商
Bressy C, Droby G, Maldonado B, Steuerwald N, Grdzelishvili V. Cell Cycle Arrest in G2/M Phase Enhances Replication of Interferon-Sensitive Cytoplasmic RNA Viruses via Inhibition of Antiviral Gene Expression. J Virol. 2019;93: pubmed 出版商
Matkovic R, Bernard E, Fontanel S, Eldin P, Chazal N, Hassan Hersi D, et al. The Host DHX9 DExH-Box Helicase Is Recruited to Chikungunya Virus Replication Complexes for Optimal Genomic RNA Translation. J Virol. 2019;93: pubmed 出版商
Ratcliffe C, Siddiqui N, Coelho P, Laterreur N, Cookey T, Sonenberg N, et al. HGF-induced migration depends on the PI(3,4,5)P3-binding microexon-spliced variant of the Arf6 exchange factor cytohesin-1. J Cell Biol. 2019;218:285-298 pubmed 出版商
Simhadri S, Vincelli G, Huo Y, Misenko S, Foo T, Ahlskog J, et al. PALB2 connects BRCA1 and BRCA2 in the G2/M checkpoint response. Oncogene. 2019;38:1585-1596 pubmed 出版商
Wang Y, Sun H, Kumar S, Puerta M, Jo H, Rezvan A. ZBTB46 is a shear-sensitive transcription factor inhibiting endothelial cell proliferation via gene expression regulation of cell cycle proteins. Lab Invest. 2019;99:305-318 pubmed 出版商
Masola V, Bellin G, Vischini G, Dall Olmo L, Granata S, Gambaro G, et al. Inhibition of heparanase protects against chronic kidney dysfunction following ischemia/reperfusion injury. Oncotarget. 2018;9:36185-36201 pubmed 出版商
Kim J, Afshari A, Sengupta R, Sebastiano V, Gupta A, Kim Y, et al. Replication study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. elife. 2018;7: pubmed 出版商
Shi M, Chen B, Mahajan D, Boh B, Zhou Y, Dutta B, et al. Amino acids stimulate the endosome-to-Golgi trafficking through Ragulator and small GTPase Arl5. Nat Commun. 2018;9:4987 pubmed 出版商
Cheng C, Qi Y, Wang Y, Chi K, Chung Y, Ouyang C, et al. Arginine starvation kills tumor cells through aspartate exhaustion and mitochondrial dysfunction. Commun Biol. 2018;1:178 pubmed 出版商
Xia P, Liu Y, Chen J, Coates S, Liu D, Cheng Z. Inhibition of cyclin-dependent kinase 2 protects against doxorubicin-induced cardiomyocyte apoptosis and cardiomyopathy. J Biol Chem. 2018;293:19672-19685 pubmed 出版商
Kim Y, Park W, Ahn S, Sung D, Chang Y. Intratracheal transplantation of mesenchymal stem cells attenuates hyperoxia-induced lung injury by down-regulating, but not direct inhibiting formyl peptide receptor 1 in the newborn mice. PLoS ONE. 2018;13:e0206311 pubmed 出版商
Kabacik S, Horvath S, Cohen H, Raj K. Epigenetic ageing is distinct from senescence-mediated ageing and is not prevented by telomerase expression. Aging (Albany NY). 2018;10:2800-2815 pubmed 出版商
Muramatsu M, Akakura S, Gao L, Peresie J, Balderman B, Gelman I. SSeCKS/Akap12 suppresses metastatic melanoma lung colonization by attenuating Src-mediated pre-metastatic niche crosstalk. Oncotarget. 2018;9:33515-33527 pubmed 出版商
Li W, Yue F, Dai Y, Shi B, Xu G, Jiang X, et al. Suppressor of hepatocellular carcinoma RASSF1A activates autophagy initiation and maturation. Cell Death Differ. 2018;: pubmed 出版商
Inoue K, Deng Z, Chen Y, Giannopoulou E, Xu R, Gong S, et al. Bone protection by inhibition of microRNA-182. Nat Commun. 2018;9:4108 pubmed 出版商
Dong P, Zhang X, Zhao J, Li D, Li L, Yang B. Anti-microRNA-132 causes sevoflurane‑induced neuronal apoptosis via the PI3K/AKT/FOXO3a pathway. Int J Mol Med. 2018;42:3238-3246 pubmed 出版商
Pan H, Palekar R, Hou K, Bacon J, Yan H, Springer L, et al. Anti-JNK2 peptide-siRNA nanostructures improve plaque endothelium and reduce thrombotic risk in atherosclerotic mice. Int J Nanomedicine. 2018;13:5187-5205 pubmed 出版商
Ma Z, Sun H, Lv J, Guo L, Yang Q. Expression and clinical significance of the NEK7-NLRP3 inflammasome signaling pathway in patients with systemic lupus erythematosus. J Inflamm (Lond). 2018;15:16 pubmed 出版商
Cai W, Wu S, Pan Z, Xiao J, Li F, Cao J, et al. Disrupting interaction of PSD-95 with nNOS attenuates hemorrhage-induced thalamic pain. Neuropharmacology. 2018;141:238-248 pubmed 出版商
Abbasi F, Miyata H, Shimada K, Morohoshi A, Nozawa K, Matsumura T, et al. RSPH6A is required for sperm flagellum formation and male fertility in mice. J Cell Sci. 2018;131: pubmed 出版商
Zhang L, Li X, Chao Y, He R, Liu J, Yuan Y, et al. KLF4, a miR-32-5p targeted gene, promotes cisplatin-induced apoptosis by upregulating BIK expression in prostate cancer. Cell Commun Signal. 2018;16:53 pubmed 出版商
Mackey L, Annab L, Yang J, Rao B, Kissling G, Schurman S, et al. Epigenetic Enzymes, Age, and Ancestry Regulate the Efficiency of Human iPSC Reprogramming. Stem Cells. 2018;36:1697-1708 pubmed 出版商
Lee M, Han H, Han S, Kim I, Chae S, Lee C, et al. Loss of the E3 ubiquitin ligase MKRN1 represses diet-induced metabolic syndrome through AMPK activation. Nat Commun. 2018;9:3404 pubmed 出版商
Lei K, Sun R, Chen L, Diplas B, Moure C, Wang W, et al. Mutant allele quantification reveals a genetic basis for TP53 mutation-driven castration resistance in prostate cancer cells. Sci Rep. 2018;8:12507 pubmed 出版商
Kwapis J, Alaghband Y, Kramar E, Lopez A, Vogel Ciernia A, White A, et al. Epigenetic regulation of the circadian gene Per1 contributes to age-related changes in hippocampal memory. Nat Commun. 2018;9:3323 pubmed 出版商
Kong X, Martinez Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick E, et al. Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency. Nat Immunol. 2018;19:973-985 pubmed 出版商
Richardson B, Jain A, Potteti H, Lazzara P, David B, Tamatam C, et al. Replacement of a Naphthalene Scaffold in Kelch-like ECH-Associated Protein 1 (KEAP1)/Nuclear Factor (Erythroid-derived 2)-like 2 (NRF2) Inhibitors. J Med Chem. 2018;61:8029-8047 pubmed 出版商
Lamothe S, Hogan Cann A, Li W, Guo J, Yang T, Tschirhart J, et al. The N terminus and transmembrane segment S1 of Kv1.5 can coassemble with the rest of the channel independently of the S1-S2 linkage. J Biol Chem. 2018;293:15347-15358 pubmed 出版商
Latremoliere A, Cheng L, DeLisle M, Wu C, Chew S, Hutchinson E, et al. Neuronal-Specific TUBB3 Is Not Required for Normal Neuronal Function but Is Essential for Timely Axon Regeneration. Cell Rep. 2018;24:1865-1879.e9 pubmed 出版商
Qian K, Feng L, Sun Y, Xiong B, Ding Y, Han P, et al. Overexpression of Salusin-α Inhibits Vascular Intimal Hyperplasia in an Atherosclerotic Rabbit Model. Biomed Res Int. 2018;2018:8973986 pubmed 出版商
Zhang D, Lin J, Chao Y, Zhang L, Jin L, Li N, et al. Regulation of the adaptation to ER stress by KLF4 facilitates melanoma cell metastasis via upregulating NUCB2 expression. J Exp Clin Cancer Res. 2018;37:176 pubmed 出版商
Freimer J, Hu T, Blelloch R. Decoupling the impact of microRNAs on translational repression versus RNA degradation in embryonic stem cells. elife. 2018;7: pubmed 出版商
Kühnl A, Musiol A, Heitzig N, Johnson D, Ehrhardt C, Grewal T, et al. Late Endosomal/Lysosomal Cholesterol Accumulation Is a Host Cell-Protective Mechanism Inhibiting Endosomal Escape of Influenza A Virus. MBio. 2018;9: pubmed 出版商
Sizemore G, Balakrishnan S, Thies K, Hammer A, Sizemore S, TRIMBOLI A, et al. Stromal PTEN determines mammary epithelial response to radiotherapy. Nat Commun. 2018;9:2783 pubmed 出版商
Zhao X, Yu H, Yang Y, Wu W, Chen T, Jia K, et al. Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway. Redox Biol. 2018;18:124-137 pubmed 出版商
Sabbir M, Calcutt N, Fernyhough P. Muscarinic Acetylcholine Type 1 Receptor Activity Constrains Neurite Outgrowth by Inhibiting Microtubule Polymerization and Mitochondrial Trafficking in Adult Sensory Neurons. Front Neurosci. 2018;12:402 pubmed 出版商
Langlois A, Marinach C, Manzoni G, Silvie O. Plasmodium sporozoites can invade hepatocytic cells independently of the Ephrin receptor A2. PLoS ONE. 2018;13:e0200032 pubmed 出版商
Bonacci T, Suzuki A, Grant G, Stanley N, Cook J, Brown N, et al. Cezanne/OTUD7B is a cell cycle-regulated deubiquitinase that antagonizes the degradation of APC/C substrates. EMBO J. 2018;37: pubmed 出版商
Okano Uchida T, Kent L, Ouseph M, McCarty B, Frank J, Kladney R, et al. Endoreduplication of the mouse genome in the absence of ORC1. Genes Dev. 2018;32:978-990 pubmed 出版商
Barutcu S, Girnius N, Vernia S, Davis R. Role of the MAPK/cJun NH2-terminal kinase signaling pathway in starvation-induced autophagy. Autophagy. 2018;14:1586-1595 pubmed 出版商
Stein C, Jadiya P, Zhang X, McLendon J, Abouassaly G, Witmer N, et al. Mitoregulin: A lncRNA-Encoded Microprotein that Supports Mitochondrial Supercomplexes and Respiratory Efficiency. Cell Rep. 2018;23:3710-3720.e8 pubmed 出版商
Jayson C, Arlt H, Fischer A, Lai Z, Farese R, Walther T. Rab18 is not necessary for lipid droplet biogenesis or turnover in human mammary carcinoma cells. Mol Biol Cell. 2018;29:2045-2054 pubmed 出版商
Kaneko S, Li X. X chromosome protects against bladder cancer in females via a KDM6A-dependent epigenetic mechanism. Sci Adv. 2018;4:eaar5598 pubmed 出版商
Tiwarekar V, Wohlfahrt J, Fehrholz M, Scholz C, Kneitz S, Schneider Schaulies J. APOBEC3G-Regulated Host Factors Interfere with Measles Virus Replication: Role of REDD1 and Mammalian TORC1 Inhibition. J Virol. 2018;92: pubmed 出版商
Zonneville J, Safina A, Truskinovsky A, Arteaga C, Bakin A. TGF-β signaling promotes tumor vasculature by enhancing the pericyte-endothelium association. BMC Cancer. 2018;18:670 pubmed 出版商
Brennan L, McGreal Estrada R, Logan C, Cvekl A, Menko A, Kantorow M. BNIP3L/NIX is required for elimination of mitochondria, endoplasmic reticulum and Golgi apparatus during eye lens organelle-free zone formation. Exp Eye Res. 2018;174:173-184 pubmed 出版商
Back M, Ha H, Fu Z, Choi J, Piao Y, Won J, et al. Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide. Cell Death Dis. 2018;9:670 pubmed 出版商
Brown Z, Fu Q, Ma C, Kruhlak M, Zhang H, Luo J, et al. Carnitine palmitoyltransferase gene upregulation by linoleic acid induces CD4+ T cell apoptosis promoting HCC development. Cell Death Dis. 2018;9:620 pubmed 出版商
Reddy V, Chinta K, Saini V, Glasgow J, Hull T, Traylor A, et al. Ferritin H Deficiency in Myeloid Compartments Dysregulates Host Energy Metabolism and Increases Susceptibility to Mycobacterium tuberculosis Infection. Front Immunol. 2018;9:860 pubmed 出版商
Liu H, Lorenzini P, Zhang F, Xu S, Wong M, Zheng J, et al. Alternative splicing analysis in human monocytes and macrophages reveals MBNL1 as major regulator. Nucleic Acids Res. 2018;46:6069-6086 pubmed 出版商
Ménard M, Costechareyre C, Ichim G, Blachier J, Neves D, Jarrosson Wuilleme L, et al. Hey1- and p53-dependent TrkC proapoptotic activity controls neuroblastoma growth. PLoS Biol. 2018;16:e2002912 pubmed 出版商
Wang Q, Gao G, Zhang T, Yao K, Chen H, Park M, et al. TRAF1 Is Critical for Regulating the BRAF/MEK/ERK Pathway in Non-Small Cell Lung Carcinogenesis. Cancer Res. 2018;78:3982-3994 pubmed 出版商
Walker J, Bleaken B, Romisher A, Alnwibit A, Menko A. In wound repair vimentin mediates the transition of mesenchymal leader cells to a myofibroblast phenotype. Mol Biol Cell. 2018;29:1555-1570 pubmed 出版商
Aboudehen K, Farahani S, Kanchwala M, Chan S, Avdulov S, Mickelson A, et al. Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling. J Biol Chem. 2018;293:9388-9398 pubmed 出版商
Stroobants S, Wolf H, Callaerts Vegh Z, Dierks T, Lübke T, D Hooge R. Sensorimotor and Neurocognitive Dysfunctions Parallel Early Telencephalic Neuropathology in Fucosidosis Mice. Front Behav Neurosci. 2018;12:69 pubmed 出版商
Peng X, Xu X, Wang Y, Hawke D, Yu S, Han L, et al. A-to-I RNA Editing Contributes to Proteomic Diversity in Cancer. Cancer Cell. 2018;33:817-828.e7 pubmed 出版商
Ge J, Burnier L, Adamopoulou M, Kwa M, Schaks M, Rottner K, et al. RhoA, Rac1, and Cdc42 differentially regulate αSMA and collagen I expression in mesenchymal stem cells. J Biol Chem. 2018;293:9358-9369 pubmed 出版商
Zhou L, Wang Y, Zhou M, Zhang Y, Wang P, Li X, et al. HOXA9 inhibits HIF-1α-mediated glycolysis through interacting with CRIP2 to repress cutaneous squamous cell carcinoma development. Nat Commun. 2018;9:1480 pubmed 出版商
Guissart C, Latypova X, Rollier P, Khan T, Stamberger H, McWalter K, et al. Dual Molecular Effects of Dominant RORA Mutations Cause Two Variants of Syndromic Intellectual Disability with Either Autism or Cerebellar Ataxia. Am J Hum Genet. 2018;102:744-759 pubmed 出版商
Yu X, Zhang Y, Ma X, Pertsemlidis A. miR-195 potentiates the efficacy of microtubule-targeting agents in non-small cell lung cancer. Cancer Lett. 2018;427:85-93 pubmed 出版商
Wang Z, Yang B, Zhang M, Guo W, Wu Z, Wang Y, et al. lncRNA Epigenetic Landscape Analysis Identifies EPIC1 as an Oncogenic lncRNA that Interacts with MYC and Promotes Cell-Cycle Progression in Cancer. Cancer Cell. 2018;33:706-720.e9 pubmed 出版商
Pentimalli F, Forte I, Esposito L, Indovina P, Iannuzzi C, Alfano L, et al. RBL2/p130 is a direct AKT target and is required to induce apoptosis upon AKT inhibition in lung cancer and mesothelioma cell lines. Oncogene. 2018;37:3657-3671 pubmed 出版商
Liu N, Hargreaves V, Zhu Q, Kurland J, Hong J, Kim W, et al. Direct Promoter Repression by BCL11A Controls the Fetal to Adult Hemoglobin Switch. Cell. 2018;173:430-442.e17 pubmed 出版商
Pan L, Wu Y, Wang R, Chen J, Chen J, Zhang Y, et al. (-)-Epigallocatechin-3-Gallate Ameliorates Atherosclerosis and Modulates Hepatic Lipid Metabolic Gene Expression in Apolipoprotein E Knockout Mice: Involvement of TTC39B. Front Pharmacol. 2018;9:195 pubmed 出版商
Kraakman M, Liu Q, Postigo Fernandez J, Ji R, Kon N, Larrea D, et al. PPAR? deacetylation dissociates thiazolidinedione's metabolic benefits from its adverse effects. J Clin Invest. 2018;128:2600-2612 pubmed 出版商
Kinyua A, Doan K, Yang D, Huynh M, Choi Y, Shin D, et al. Insulin Regulates Adrenal Steroidogenesis by Stabilizing SF-1 Activity. Sci Rep. 2018;8:5025 pubmed 出版商
Russell J, Ko S, Saggi H, Singh S, Poddar M, Shin D, et al. Bromodomain and Extraterminal (BET) Proteins Regulate Hepatocyte Proliferation in Hepatocyte-Driven Liver Regeneration. Am J Pathol. 2018;188:1389-1405 pubmed 出版商
Lin C, Kitagawa M, Tang X, Hou M, Wu J, Qu D, et al. CoA synthase regulates mitotic fidelity via CBP-mediated acetylation. Nat Commun. 2018;9:1039 pubmed 出版商
Danyukova T, Ariunbat K, Thelen M, Brocke Ahmadinejad N, Mole S, Storch S. Loss of CLN7 results in depletion of soluble lysosomal proteins and impaired mTOR reactivation. Hum Mol Genet. 2018;27:1711-1722 pubmed 出版商
Wang Q, Yu J, Kadungure T, Beyene J, Zhang H, Lu Q. ARMMs as a versatile platform for intracellular delivery of macromolecules. Nat Commun. 2018;9:960 pubmed 出版商
Sarikhani M, Mishra S, Maity S, Kotyada C, Wolfgeher D, Gupta M, et al. SIRT2 deacetylase regulates the activity of GSK3 isoforms independent of inhibitory phosphorylation. elife. 2018;7: pubmed 出版商
Zhao Y, Mao M, Zhang W, Wang J, Li H, Yang Y, et al. Expanding RNA binding specificity and affinity of engineered PUF domains. Nucleic Acids Res. 2018;46:4771-4782 pubmed 出版商
Delorme Axford E, Abernathy E, Lennemann N, Bernard A, Ariosa A, Coyne C, et al. The exoribonuclease Xrn1 is a post-transcriptional negative regulator of autophagy. Autophagy. 2018;14:898-912 pubmed 出版商
Lu D, Liao H, Chen C, Tu H, Liou H, Gau S, et al. Impairment of social behaviors in Arhgef10 knockout mice. Mol Autism. 2018;9:11 pubmed 出版商
Wu Q, Xiao Y, Duan M, Yuan Y, Jiang X, Yang Z, et al. Aucubin protects against pressure overload-induced cardiac remodelling via the β3 -adrenoceptor-neuronal NOS cascades. Br J Pharmacol. 2018;175:1548-1566 pubmed 出版商
Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed 出版商
Zhang F, Brenner M, Yang W, Wang P. A cold-inducible RNA-binding protein (CIRP)-derived peptide attenuates inflammation and organ injury in septic mice. Sci Rep. 2018;8:3052 pubmed 出版商
Wang S, Hu B, Ding Z, Dang Y, Wu J, Li D, et al. ATF6 safeguards organelle homeostasis and cellular aging in human mesenchymal stem cells. Cell Discov. 2018;4:2 pubmed 出版商
Legler K, Rosprim R, Karius T, Eylmann K, Rossberg M, Wirtz R, et al. Reduced mannosidase MAN1A1 expression leads to aberrant N-glycosylation and impaired survival in breast cancer. Br J Cancer. 2018;118:847-856 pubmed 出版商
Jiang M, Xu C, Guo Y, Luo Q, Li L, Liu H, et al. ?-arrestin 2 attenuates lipopolysaccharide-induced liver injury via inhibition of TLR4/NF-?B signaling pathway-mediated inflammation in mice. World J Gastroenterol. 2018;24:216-225 pubmed 出版商
Liang H, Xiao J, Zhou Z, Wu J, Ge F, Li Z, et al. Hypoxia induces miR-153 through the IRE1α-XBP1 pathway to fine tune the HIF1α/VEGFA axis in breast cancer angiogenesis. Oncogene. 2018;37:1961-1975 pubmed 出版商
Uchino Y, Woodward A, Mauris J, Peterson K, Verma P, Nilsson U, et al. Galectin-3 is an amplifier of the interleukin-1β-mediated inflammatory response in corneal keratinocytes. Immunology. 2018;154:490-499 pubmed 出版商
Leo D, Sukhanov I, Zoratto F, Illiano P, Caffino L, Sanna F, et al. Pronounced Hyperactivity, Cognitive Dysfunctions, and BDNF Dysregulation in Dopamine Transporter Knock-out Rats. J Neurosci. 2018;38:1959-1972 pubmed 出版商
Liang Y, Liu L, Jin Z, Liang X, Fu Y, Gu X, et al. The high concentration of progesterone is harmful for endometrial receptivity and decidualization. Sci Rep. 2018;8:712 pubmed 出版商
Li Y, Shang P, Shyu D, Carrillo C, Naraghi Arani P, Jaing C, et al. Nonstructural proteins nsp2TF and nsp2N of porcine reproductive and respiratory syndrome virus (PRRSV) play important roles in suppressing host innate immune responses. Virology. 2018;517:164-176 pubmed 出版商
Choi J, Kim K, Koh E, Lee B. Gelidium elegans Extract Ameliorates Type 2 Diabetes via Regulation of MAPK and PI3K/Akt Signaling. Nutrients. 2018;10: pubmed 出版商
Ding D, Bergmaier P, Sachs P, Klangwart M, Rückert T, Bartels N, et al. The CUE1 domain of the SNF2-like chromatin remodeler SMARCAD1 mediates its association with KRAB-associated protein 1 (KAP1) and KAP1 target genes. J Biol Chem. 2018;293:2711-2724 pubmed 出版商
Su Y, Chen R, Wang H, Song H, Zhang Q, Chen L, et al. Novel Targeting of Transcription and Metabolism in Glioblastoma. Clin Cancer Res. 2018;24:1124-1137 pubmed 出版商
Park S, Lee H, Seo Y, Son C, Bae H, Park J. Dentin sialophosphoprotein expression in enamel is regulated by Copine-7, a preameloblast-derived factor. Arch Oral Biol. 2018;86:131-137 pubmed 出版商
Abdul A, De Silva B, Gary R. The GSK3 kinase inhibitor lithium produces unexpected hyperphosphorylation of β-catenin, a GSK3 substrate, in human glioblastoma cells. Biol Open. 2018;7: pubmed 出版商
McNair C, Xu K, Mandigo A, Benelli M, Leiby B, Rodrigues D, et al. Differential impact of RB status on E2F1 reprogramming in human cancer. J Clin Invest. 2018;128:341-358 pubmed 出版商
Kullar P, Gómez Durán A, Gammage P, Garone C, Minczuk M, Golder Z, et al. Heterozygous SSBP1 start loss mutation co-segregates with hearing loss and the m.1555A>G mtDNA variant in a large multigenerational family. Brain. 2018;141:55-62 pubmed 出版商
Deng J, Orsini C, Shimp K, Setlow B. MeCP2 Expression in a Rat Model of Risky Decision Making. Neuroscience. 2018;369:212-221 pubmed 出版商
Koon H, Wang J, Mussatto C, Ortiz C, Lee E, Tran D, et al. Fidaxomicin and OP-1118 Inhibit Clostridium difficile Toxin A- and B-Mediated Inflammatory Responses via Inhibition of NF-κB Activity. Antimicrob Agents Chemother. 2018;62: pubmed 出版商
Siraj A, Masoodi T, Bu R, Pratheeshkumar P, Al Sanea N, Ashari L, et al. MED12 is recurrently mutated in Middle Eastern colorectal cancer. Gut. 2018;67:663-671 pubmed 出版商
Namasu C, Katzerke C, Bräuer Hartmann D, Wurm A, Gerloff D, Hartmann J, et al. ABR, a novel inducer of transcription factor C/EBP?, contributes to myeloid differentiation and is a favorable prognostic factor in acute myeloid leukemia. Oncotarget. 2017;8:103626-103639 pubmed 出版商
Chen G, Du C, Shen Z, Peng L, Xie H, Zang R, et al. MicroRNA-939 inhibits cell proliferation via targeting LRSAM1 in Hirschsprung's disease. Aging (Albany NY). 2017;9:2471-2479 pubmed 出版商
Cho M, Lee J, Shin M, Kim H, Choi Y, Rho S, et al. TSC-22 inhibits CSF-1R function and induces apoptosis in cervical cancer. Oncotarget. 2017;8:97990-98003 pubmed 出版商
Wu S, Lu Q, Wang N, Zhang J, Liu Q, Gao M, et al. Cyclic stretch induced-retinal pigment epithelial cell apoptosis and cytokine changes. BMC Ophthalmol. 2017;17:208 pubmed 出版商
Yu L, Liu S, Zhao Z, Xia L, Zhang H, Lou J, et al. Extracorporeal Shock Wave Rebuilt Subchondral Bone In Vivo and Activated Wnt5a/Ca2+ Signaling In Vitro. Biomed Res Int. 2017;2017:1404650 pubmed 出版商
Fung K, Wang C, Nyegaard S, Heit B, Fairn G, Lee W. SR-BI Mediated Transcytosis of HDL in Brain Microvascular Endothelial Cells Is Independent of Caveolin, Clathrin, and PDZK1. Front Physiol. 2017;8:841 pubmed 出版商
Liu Z, Zhang C, Skamagki M, Khodadadi Jamayran A, Zhang W, Kong D, et al. Elevated p53 Activities Restrict Differentiation Potential of MicroRNA-Deficient Pluripotent Stem Cells. Stem Cell Reports. 2017;9:1604-1617 pubmed 出版商
Wu X, Shi T, He Y, Wang F, Sang R, Ding J, et al. Methylation of transcription factor YY2 regulates its transcriptional activity and cell proliferation. Cell Discov. 2017;3:17035 pubmed 出版商
Kang H, Kumar D, Liao G, Lichti Kaiser K, Gerrish K, Liao X, et al. GLIS3 is indispensable for TSH/TSHR-dependent thyroid hormone biosynthesis and follicular cell proliferation. J Clin Invest. 2017;127:4326-4337 pubmed 出版商
Xue X, Bredell B, Anderson E, Martin A, Mays C, Nagao Kitamoto H, et al. Quantitative proteomics identifies STEAP4 as a critical regulator of mitochondrial dysfunction linking inflammation and colon cancer. Proc Natl Acad Sci U S A. 2017;114:E9608-E9617 pubmed 出版商
Muramatsu M, Gao L, Peresie J, Balderman B, Akakura S, Gelman I. SSeCKS/AKAP12 scaffolding functions suppress B16F10-induced peritoneal metastasis by attenuating CXCL9/10 secretion by resident fibroblasts. Oncotarget. 2017;8:70281-70298 pubmed 出版商
Yue J, Lai F, Beckedorff F, Zhang A, Pastori C, Shiekhattar R. Integrator orchestrates RAS/ERK1/2 signaling transcriptional programs. Genes Dev. 2017;31:1809-1820 pubmed 出版商
Lavallée Adam M, Cloutier P, Coulombe B, Blanchette M. Functional 5' UTR motif discovery with LESMoN: Local Enrichment of Sequence Motifs in biological Networks. Nucleic Acids Res. 2017;45:10415-10427 pubmed 出版商
Masoodi K, Eisermann K, Yang Z, Dar J, Pascal L, Nguyen M, et al. Inhibition of Androgen Receptor Function and Level in Castration-Resistant Prostate Cancer Cells by 2-[(isoxazol-4-ylmethyl)thio]-1-(4-phenylpiperazin-1-yl)ethanone. Endocrinology. 2017;158:3152-3161 pubmed 出版商
Softic S, Gupta M, Wang G, Fujisaka S, O Neill B, Rao T, et al. Divergent effects of glucose and fructose on hepatic lipogenesis and insulin signaling. J Clin Invest. 2017;127:4059-4074 pubmed 出版商
Cao H, Zhang S, Shan S, Sun C, Li Y, Yu S, et al. Ligand-dependent corepressor (LCoR) represses the transcription factor C/EBPβ during early adipocyte differentiation. J Biol Chem. 2017;292:18973-18987 pubmed 出版商
Pham T, He J, Kakazu A, Jun B, Bazan N, Bazan H. Defining a mechanistic link between pigment epithelium-derived factor, docosahexaenoic acid, and corneal nerve regeneration. J Biol Chem. 2017;292:18486-18499 pubmed 出版商
Onodera Y, Teramura T, Takehara T, Obora K, Mori T, Fukuda K. miR-155 induces ROS generation through downregulation of antioxidation-related genes in mesenchymal stem cells. Aging Cell. 2017;16:1369-1380 pubmed 出版商
George J, Jolly M, Xu S, Somarelli J, Levine H. Survival Outcomes in Cancer Patients Predicted by a Partial EMT Gene Expression Scoring Metric. Cancer Res. 2017;77:6415-6428 pubmed 出版商
Waraky A, Lin Y, Warsito D, Haglund F, Aleem E, Larsson O. Nuclear insulin-like growth factor 1 receptor phosphorylates proliferating cell nuclear antigen and rescues stalled replication forks after DNA damage. J Biol Chem. 2017;292:18227-18239 pubmed 出版商
Skarra D, Hernandez Carretero A, Rivera A, Anvar A, Thackray V. Hyperandrogenemia Induced by Letrozole Treatment of Pubertal Female Mice Results in Hyperinsulinemia Prior to Weight Gain and Insulin Resistance. Endocrinology. 2017;158:2988-3003 pubmed 出版商
Wood M, Ishiyama N, Singaram I, Chung C, Flozak A, Yemelyanov A, et al. α-Catenin homodimers are recruited to phosphoinositide-activated membranes to promote adhesion. J Cell Biol. 2017;216:3767-3783 pubmed 出版商
Pascal L, Masoodi K, Liu J, Qiu X, Song Q, Wang Y, et al. Conditional deletion of ELL2 induces murine prostate intraepithelial neoplasia. J Endocrinol. 2017;235:123-136 pubmed 出版商
Li X, Wang C, Zhang G, Liang M, Zhang B. AKAP2 is upregulated in ovarian cancer, and promotes growth and migration of cancer cells. Mol Med Rep. 2017;16:5151-5156 pubmed 出版商
Feng Y, Lund J, Li Y, Knabenes I, Bakke S, Kase E, et al. Loss of perilipin 2 in cultured myotubes enhances lipolysis and redirects the metabolic energy balance from glucose oxidation towards fatty acid oxidation. J Lipid Res. 2017;58:2147-2161 pubmed 出版商
Zaytouni T, Tsai P, Hitchcock D, DuBois C, Freinkman E, Lin L, et al. Critical role for arginase 2 in obesity-associated pancreatic cancer. Nat Commun. 2017;8:242 pubmed 出版商
Oh D, Jung K, Song J, Kim S, Shin S, Kwon Y, et al. Precision medicine approaches to lung adenocarcinoma with concomitant MET and HER2 amplification. BMC Cancer. 2017;17:535 pubmed 出版商
Tong X, Zhang D, Charney N, Jin E, VanDommelen K, Stamper K, et al. DDB1-Mediated CRY1 Degradation Promotes FOXO1-Driven Gluconeogenesis in Liver. Diabetes. 2017;66:2571-2582 pubmed 出版商
Delaney M, Malikov V, Chai Q, Zhao G, Naghavi M. Distinct functions of diaphanous-related formins regulate HIV-1 uncoating and transport. Proc Natl Acad Sci U S A. 2017;114:E6932-E6941 pubmed 出版商
Norante R, Massimino M, Lorenzon P, De Mario A, Peggion C, Vicario M, et al. Generation and validation of novel adeno-associated viral vectors for the analysis of Ca2+ homeostasis in motor neurons. Sci Rep. 2017;7:6521 pubmed 出版商
Sui Z, Gokhin D, Nowak R, Guo X, An X, Fowler V. Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells. Mol Biol Cell. 2017;28:2531-2542 pubmed 出版商
Li L, Zviti R, Ha C, Wang Z, Hill J, Lin F. Forkhead box O3 (FoxO3) regulates kidney tubular autophagy following urinary tract obstruction. J Biol Chem. 2017;292:13774-13783 pubmed 出版商
Kroh H, Chandrasekaran R, Rosenthal K, Woods R, Jin X, Ohi M, et al. Use of a neutralizing antibody helps identify structural features critical for binding of Clostridium difficile toxin TcdA to the host cell surface. J Biol Chem. 2017;292:14401-14412 pubmed 出版商
Wurm A, Zjablovskaja P, Kardosova M, Gerloff D, Bräuer Hartmann D, Katzerke C, et al. Disruption of the C/EBP?-miR-182 balance impairs granulocytic differentiation. Nat Commun. 2017;8:46 pubmed 出版商
McClatchie T, Meredith M, Ouédraogo M, Slow S, Lever M, Mann M, et al. Betaine is accumulated via transient choline dehydrogenase activation during mouse oocyte meiotic maturation. J Biol Chem. 2017;292:13784-13794 pubmed 出版商
Miles L, Burga L, Gardner E, Bostina M, Poirier J, Rudin C. Anthrax toxin receptor 1 is the cellular receptor for Seneca Valley virus. J Clin Invest. 2017;127:2957-2967 pubmed 出版商
Fei T, Chen Y, Xiao T, Li W, Cato L, Zhang P, et al. Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing. Proc Natl Acad Sci U S A. 2017;114:E5207-E5215 pubmed 出版商
Smith S, Mellor P, Ward A, Kendall S, McDonald M, Vizeacoumar F, et al. Molecular characterization of breast cancer cell lines through multiple omic approaches. Breast Cancer Res. 2017;19:65 pubmed 出版商
Suleymanova N, Crudden C, Shibano T, Worrall C, Oprea I, Tica A, et al. Functional antagonism of β-arrestin isoforms balance IGF-1R expression and signalling with distinct cancer-related biological outcomes. Oncogene. 2017;36:5734-5744 pubmed 出版商
Felt S, Droby G, Grdzelishvili V. Ruxolitinib and Polycation Combination Treatment Overcomes Multiple Mechanisms of Resistance of Pancreatic Cancer Cells to Oncolytic Vesicular Stomatitis Virus. J Virol. 2017;91: pubmed 出版商
Mompeán M, Romano V, Pantoja Uceda D, Stuani C, Baralle F, Buratti E, et al. Point mutations in the N-terminal domain of transactive response DNA-binding protein 43 kDa (TDP-43) compromise its stability, dimerization, and functions. J Biol Chem. 2017;292:11992-12006 pubmed 出版商
Sahu S, Kumar M, Chakraborty S, Banerjee S, Kumar R, Gupta P, et al. MicroRNA 26a (miR-26a)/KLF4 and CREB-C/EBPβ regulate innate immune signaling, the polarization of macrophages and the trafficking of Mycobacterium tuberculosis to lysosomes during infection. PLoS Pathog. 2017;13:e1006410 pubmed 出版商
Kim J, Toda C, Ramírez C, Fernandez Hernando C, Diano S. Hypothalamic Ventromedial Lin28a Enhances Glucose Metabolism in Diet-Induced Obesity. Diabetes. 2017;66:2102-2111 pubmed 出版商
Loers G, Astafiev S, Hapiak Y, Saini V, Mishra B, Gul S, et al. The polysialic acid mimetics idarubicin and irinotecan stimulate neuronal survival and neurite outgrowth and signal via protein kinase C. J Neurochem. 2017;142:392-406 pubmed 出版商
Vieira N, Spinazzola J, Alexander M, Moreira Y, Kawahara G, Gibbs D, et al. Repression of phosphatidylinositol transfer protein ? ameliorates the pathology of Duchenne muscular dystrophy. Proc Natl Acad Sci U S A. 2017;114:6080-6085 pubmed 出版商
Kawasaki S, Fujita Y, Nagaike T, Tomita K, Saito H. Synthetic mRNA devices that detect endogenous proteins and distinguish mammalian cells. Nucleic Acids Res. 2017;45:e117 pubmed 出版商
Nam M, Akie T, Sanosaka M, Craige S, Kant S, Keaney J, et al. Mitochondrial retrograde signaling connects respiratory capacity to thermogenic gene expression. Sci Rep. 2017;7:2013 pubmed 出版商
Zaritsky A, Tseng Y, Rabadán M, Krishna S, Overholtzer M, Danuser G, et al. Diverse roles of guanine nucleotide exchange factors in regulating collective cell migration. J Cell Biol. 2017;216:1543-1556 pubmed 出版商
Leikas J, Kohtala S, Theilmann W, Jalkanen A, Forsberg M, Rantamäki T. Brief isoflurane anesthesia regulates striatal AKT-GSK3? signaling and ameliorates motor deficits in a rat model of early-stage Parkinson's disease. J Neurochem. 2017;142:456-463 pubmed 出版商
Gu J, Chen F, Iqbal K, Gong C, Wang X, Liu F. Transactive response DNA-binding protein 43 (TDP-43) regulates alternative splicing of tau exon 10: Implications for the pathogenesis of tauopathies. J Biol Chem. 2017;292:10600-10612 pubmed 出版商
Aroor A, Habibi J, Kandikattu H, Garro Kacher M, Barron B, Chen D, et al. Dipeptidyl peptidase-4 (DPP-4) inhibition with linagliptin reduces western diet-induced myocardial TRAF3IP2 expression, inflammation and fibrosis in female mice. Cardiovasc Diabetol. 2017;16:61 pubmed 出版商
Head P, Zhang H, Bastien A, Koyen A, Withers A, Daddacha W, et al. Sirtuin 2 mutations in human cancers impair its function in genome maintenance. J Biol Chem. 2017;292:9919-9931 pubmed 出版商
Sokolowski M, Chynces M, Deharo D, Christian C, Belancio V. Truncated ORF1 proteins can suppress LINE-1 retrotransposition in trans. Nucleic Acids Res. 2017;45:5294-5308 pubmed 出版商
Liu Y, Li L, An S, Zhang Y, Feng S, Zhao L, et al. Antifatigue Effects of Antrodia cinnamomea Cultured Mycelium via Modulation of Oxidative Stress Signaling in a Mouse Model. Biomed Res Int. 2017;2017:9374026 pubmed 出版商
Lu K, Alcivar A, Ma J, Foo T, Zywea S, Mahdi A, et al. NRF2 Induction Supporting Breast Cancer Cell Survival Is Enabled by Oxidative Stress-Induced DPP3-KEAP1 Interaction. Cancer Res. 2017;77:2881-2892 pubmed 出版商
Wizeman J, Mohan R. Expression of peptidylarginine deiminase 4 in an alkali injury model of retinal gliosis. Biochem Biophys Res Commun. 2017;487:134-139 pubmed 出版商
Li J, Xiu Z, Wang R, Yu C, Chi Y, Qin J, et al. The lipid moiety 7-ketocholesteryl-9-carboxynonanoate mediates binding interaction of oxLDL to LOX-1 and upregulates ABCA1 expression through PPAR?. Life Sci. 2017;177:27-40 pubmed 出版商
Liu Y, Wang J, Li L, Hu W, Qu Y, Ding Y, et al. Hepatoprotective Effects of Antrodia cinnamomea: The Modulation of Oxidative Stress Signaling in a Mouse Model of Alcohol-Induced Acute Liver Injury. Oxid Med Cell Longev. 2017;2017:7841823 pubmed 出版商
Wasik U, Milkiewicz M, Kempińska Podhorodecka A, Milkiewicz P. Protection against oxidative stress mediated by the Nrf2/Keap1 axis is impaired in Primary Biliary Cholangitis. Sci Rep. 2017;7:44769 pubmed 出版商
Moilanen J, Löffek S, Kokkonen N, Salo S, Väyrynen J, Hurskainen T, et al. Significant Role of Collagen XVII And Integrin β4 in Migration and Invasion of The Less Aggressive Squamous Cell Carcinoma Cells. Sci Rep. 2017;7:45057 pubmed 出版商
Nguyen T, Li J, Lu C, Mamrosh J, Lu G, Cathers B, et al. p97/VCP promotes degradation of CRBN substrate glutamine synthetase and neosubstrates. Proc Natl Acad Sci U S A. 2017;114:3565-3571 pubmed 出版商
Ferreira N, Engelsby H, Neess D, Kelly S, Volpert G, Merrill A, et al. Regulation of very-long acyl chain ceramide synthesis by acyl-CoA-binding protein. J Biol Chem. 2017;292:7588-7597 pubmed 出版商
Choi M, Min Y, Pyo J, Lee C, Jang C, Kim J. TC Mps1 12, a novel Mps1 inhibitor, suppresses the growth of hepatocellular carcinoma cells via the accumulation of chromosomal instability. Br J Pharmacol. 2017;174:1810-1825 pubmed 出版商
Kuo T, Chen T, Lee R, Nguyen N, Broughton A, Zhang D, et al. Pik3r1 Is Required for Glucocorticoid-Induced Perilipin 1 Phosphorylation in Lipid Droplet for Adipocyte Lipolysis. Diabetes. 2017;66:1601-1610 pubmed 出版商
Petit M, Koziel R, Etemad S, Pircher H, Jansen Durr P. Depletion of oxaloacetate decarboxylase FAHD1 inhibits mitochondrial electron transport and induces cellular senescence in human endothelial cells. Exp Gerontol. 2017;92:7-12 pubmed 出版商
Mu Y, Yan W, Yin T, Zhang Y, Li J, Yang J. Diet-induced obesity impairs spermatogenesis: a potential role for autophagy. Sci Rep. 2017;7:43475 pubmed 出版商
Wang L, Cooper J. Optogenetic control of the Dab1 signaling pathway. Sci Rep. 2017;7:43760 pubmed 出版商
Walker R, Czepnik M, Goebel E, McCoy J, Vujic A, Cho M, et al. Structural basis for potency differences between GDF8 and GDF11. BMC Biol. 2017;15:19 pubmed 出版商
Liu Y, Liu R, Yang F, Cheng R, Chen X, Cui S, et al. miR-19a promotes colorectal cancer proliferation and migration by targeting TIA1. Mol Cancer. 2017;16:53 pubmed 出版商
Liang D, Wang Z, Yan Z, Hou S, Xu W, Wang L, et al. Nicotine facilitates VSMC dysfunction through a miR-200b/RhoGDIA/cytoskeleton module. Sci Rep. 2017;7:43798 pubmed 出版商
Lerner N, Avissar S, Beit Yannai E. Extracellular vesicles mediate signaling between the aqueous humor producing and draining cells in the ocular system. PLoS ONE. 2017;12:e0171153 pubmed 出版商
Kim Y, Choe S, Cho K, Cho D, Kang J, Park C, et al. Resveratrol suppresses breast cancer cell invasion by inactivating a RhoA/YAP signaling axis. Exp Mol Med. 2017;49:e296 pubmed 出版商
Koide N, Kasamatsu A, Endo Sakamoto Y, Ishida S, Shimizu T, Kimura Y, et al. Evidence for Critical Role of Lymphocyte Cytosolic Protein 1 in Oral Cancer. Sci Rep. 2017;7:43379 pubmed 出版商
Bakshi A, Moin M, Kumar M, Reddy A, Ren M, Datla R, et al. Ectopic expression of Arabidopsis Target of Rapamycin (AtTOR) improves water-use efficiency and yield potential in rice. Sci Rep. 2017;7:42835 pubmed 出版商
An L, Hu X, Zhang S, Hu X, Song Z, Naz A, et al. UVRAG Deficiency Exacerbates Doxorubicin-Induced Cardiotoxicity. Sci Rep. 2017;7:43251 pubmed 出版商
Liu Y, Xu H, Geng Y, Xu D, Zhang L, Yang Y, et al. Dibutyryl-cAMP attenuates pulmonary fibrosis by blocking myofibroblast differentiation via PKA/CREB/CBP signaling in rats with silicosis. Respir Res. 2017;18:38 pubmed 出版商
Hsia H, Hutti J, Baldwin A. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding Kinase 1 (TBK1) to Restrain STAT3 Activity. J Biol Chem. 2017;292:5405-5417 pubmed 出版商
Barca Mayo O, Pons Espinal M, Follert P, Armirotti A, Berdondini L, De Pietri Tonelli D. Astrocyte deletion of Bmal1 alters daily locomotor activity and cognitive functions via GABA signalling. Nat Commun. 2017;8:14336 pubmed 出版商
Qiu X, Pascal L, Song Q, Zang Y, Ai J, O Malley K, et al. Physical and Functional Interactions between ELL2 and RB in the Suppression of Prostate Cancer Cell Proliferation, Migration, and Invasion. Neoplasia. 2017;19:207-215 pubmed 出版商
Kempińska Podhorodecka A, Milkiewicz M, Wasik U, Ligocka J, Zawadzki M, Krawczyk M, et al. Decreased Expression of Vitamin D Receptor Affects an Immune Response in Primary Biliary Cholangitis via the VDR-miRNA155-SOCS1 Pathway. Int J Mol Sci. 2017;18: pubmed 出版商
Biehs R, Steinlage M, Barton O, Juhasz S, Künzel J, Spies J, et al. DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination. Mol Cell. 2017;65:671-684.e5 pubmed 出版商
Cataldo L, Mizgier M, Bravo Sagua R, Jaña F, Cardenas C, Llanos P, et al. Prolonged Activation of the Htr2b Serotonin Receptor Impairs Glucose Stimulated Insulin Secretion and Mitochondrial Function in MIN6 Cells. PLoS ONE. 2017;12:e0170213 pubmed 出版商
Kissing S, Rudnik S, Damme M, Lüllmann Rauch R, Ichihara A, Kornak U, et al. Disruption of the vacuolar-type H+-ATPase complex in liver causes MTORC1-independent accumulation of autophagic vacuoles and lysosomes. Autophagy. 2017;13:670-685 pubmed 出版商
Cai L, Wang H, Yang Q. CRKL overexpression promotes cell proliferation and inhibits apoptosis in endometrial carcinoma. Oncol Lett. 2017;13:51-56 pubmed 出版商
An N, Luo X, Zhang M, Yu R. MicroRNA-376b promotes breast cancer metastasis by targeting Hoxd10 directly. Exp Ther Med. 2017;13:79-84 pubmed 出版商
Lin Y, Liu H, Waraky A, Haglund F, Agarwal P, Jernberg Wiklund H, et al. SUMO-modified insulin-like growth factor 1 receptor (IGF-1R) increases cell cycle progression and cell proliferation. J Cell Physiol. 2017;232:2722-2730 pubmed 出版商
Christian C, Sokolowski M, Deharo D, Kines K, Belancio V. Involvement of Conserved Amino Acids in the C-Terminal Region of LINE-1 ORF2p in Retrotransposition. Genetics. 2017;205:1139-1149 pubmed 出版商
Worrall C, Suleymanova N, Crudden C, Trocoli Drakensjö I, Candrea E, Nedelcu D, et al. Unbalancing p53/Mdm2/IGF-1R axis by Mdm2 activation restrains the IGF-1-dependent invasive phenotype of skin melanoma. Oncogene. 2017;36:3274-3286 pubmed 出版商
Muranen T, Iwanicki M, Curry N, Hwang J, DuBois C, Coloff J, et al. Starved epithelial cells uptake extracellular matrix for survival. Nat Commun. 2017;8:13989 pubmed 出版商
Della Mina E, Borghesi A, Zhou H, Bougarn S, Boughorbel S, Israel L, et al. Inherited human IRAK-1 deficiency selectively impairs TLR signaling in fibroblasts. Proc Natl Acad Sci U S A. 2017;114:E514-E523 pubmed 出版商
Kleinsimon S, Kauczor G, Jaeger S, Eggert A, Seifert G, Delebinski C. ViscumTT induces apoptosis and alters IAP expression in osteosarcoma in vitro and has synergistic action when combined with different chemotherapeutic drugs. BMC Complement Altern Med. 2017;17:26 pubmed 出版商
Rai V, Thomas D, Beach J, Egelhoff T. Myosin IIA Heavy Chain Phosphorylation Mediates Adhesion Maturation and Protrusion in Three Dimensions. J Biol Chem. 2017;292:3099-3111 pubmed 出版商
Liu Z, Lam N, Wang E, Virden R, Pawel B, Attiyeh E, et al. Identification of CASZ1 NES reveals potential mechanisms for loss of CASZ1 tumor suppressor activity in neuroblastoma. Oncogene. 2017;36:97-109 pubmed 出版商
Yu J, Liang Q, Wang J, Wang K, Gao J, Zhang J, et al. REC8 functions as a tumor suppressor and is epigenetically downregulated in gastric cancer, especially in EBV-positive subtype. Oncogene. 2017;36:182-193 pubmed 出版商
Gan J, Wang F, Mu D, Qu Y, Luo R, Wang Q. RNA interference targeting Aurora-A sensitizes glioblastoma cells to temozolomide chemotherapy. Oncol Lett. 2016;12:4515-4523 pubmed 出版商
Liu Z, Hui Y, Shi L, Chen Z, Xu X, Chi L, et al. Efficient CRISPR/Cas9-Mediated Versatile, Predictable, and Donor-Free Gene Knockout in Human Pluripotent Stem Cells. Stem Cell Reports. 2016;7:496-507 pubmed 出版商
Cunningham C, Li S, Vizeacoumar F, Bhanumathy K, Lee J, Parameswaran S, et al. Therapeutic relevance of the protein phosphatase 2A in cancer. Oncotarget. 2016;7:61544-61561 pubmed 出版商
Matkar P, Singh K, Rudenko D, Kim Y, Kuliszewski M, Prud homme G, et al. Novel regulatory role of neuropilin-1 in endothelial-to-mesenchymal transition and fibrosis in pancreatic ductal adenocarcinoma. Oncotarget. 2016;7:69489-69506 pubmed 出版商
Hastie E, Cataldi M, Moerdyk Schauwecker M, Felt S, Steuerwald N, Grdzelishvili V. Novel biomarkers of resistance of pancreatic cancer cells to oncolytic vesicular stomatitis virus. Oncotarget. 2016;7:61601-61618 pubmed 出版商
Crippa V, Cicardi M, Ramesh N, Seguin S, Ganassi M, Bigi I, et al. The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity. Hum Mol Genet. 2016;25:3908-3924 pubmed 出版商
Saisana M, Griffin S, May F. Importance of the type I insulin-like growth factor receptor in HER2, FGFR2 and MET-unamplified gastric cancer with and without Ras pathway activation. Oncotarget. 2016;7:54445-54462 pubmed 出版商
Pratheeshkumar P, Son Y, Divya S, Turcios L, Roy R, Hitron J, et al. Hexavalent chromium induces malignant transformation of human lung bronchial epithelial cells via ROS-dependent activation of miR-21-PDCD4 signaling. Oncotarget. 2016;7:51193-51210 pubmed 出版商
Christian C, Deharo D, Kines K, Sokolowski M, Belancio V. Identification of L1 ORF2p sequence important to retrotransposition using Bipartile Alu retrotransposition (BAR). Nucleic Acids Res. 2016;44:4818-34 pubmed 出版商
Li M, Andersson Lendahl M, Sejersen T, Arner A. Knockdown of fast skeletal myosin-binding protein C in zebrafish results in a severe skeletal myopathy. J Gen Physiol. 2016;147:309-22 pubmed 出版商
Jin H, Lee K, Kim Y, Oh H, Maeng Y, Kim T, et al. Scaffold protein FHL2 facilitates MDM2-mediated degradation of IER3 to regulate proliferation of cervical cancer cells. Oncogene. 2016;35:5106-18 pubmed 出版商
Locard Paulet M, Lim L, Veluscek G, McMahon K, Sinclair J, van Weverwijk A, et al. Phosphoproteomic analysis of interacting tumor and endothelial cells identifies regulatory mechanisms of transendothelial migration. Sci Signal. 2016;9:ra15 pubmed 出版商
Thornton T, Delgado P, Chen L, Salas B, Krementsov D, Fernández M, et al. Inactivation of nuclear GSK3β by Ser(389) phosphorylation promotes lymphocyte fitness during DNA double-strand break response. Nat Commun. 2016;7:10553 pubmed 出版商
Ying M, Zhang L, Zhou Q, Shao X, Cao J, Zhang N, et al. The E3 ubiquitin protein ligase MDM2 dictates all-trans retinoic acid-induced osteoblastic differentiation of osteosarcoma cells by modulating the degradation of RARα. Oncogene. 2016;35:4358-67 pubmed 出版商
Liu Z, Skamagki M, Kim K, Zhao R. Canonical MicroRNA Activity Facilitates but May Be Dispensable for Transcription Factor-Mediated Reprogramming. Stem Cell Reports. 2015;5:1119-1127 pubmed 出版商
Omori Y, Mano T, Ohtani T, Sakata Y, Takeda Y, Tamaki S, et al. Glucocorticoids Induce Cardiac Fibrosis via Mineralocorticoid Receptor in Oxidative Stress: Contribution of Elongation Factor Eleven-Nineteen Lysine-Rich Leukemia (ELL). Yonago Acta Med. 2014;57:109-16 pubmed
Jacobshagen M, Niquille M, Chaumont Dubel S, Marin P, Dayer A. The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism. Development. 2014;141:3370-7 pubmed 出版商
Koch L, Schmitz V, Strassburg C, Raskopf E. Plasmid transfer of plasminogen K1-5 reduces subcutaneous hepatoma growth by affecting inflammatory factors. Biomed Res Int. 2014;2014:656527 pubmed 出版商
Wang J, Ben Hamida S, Darcq E, Zhu W, Gibb S, Lanfranco M, et al. Ethanol-mediated facilitation of AMPA receptor function in the dorsomedial striatum: implications for alcohol drinking behavior. J Neurosci. 2012;32:15124-32 pubmed 出版商
Filipe Santos O, Bustamante J, Haverkamp M, Vinolo E, Ku C, Puel A, et al. X-linked susceptibility to mycobacteria is caused by mutations in NEMO impairing CD40-dependent IL-12 production. J Exp Med. 2006;203:1745-59 pubmed
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