产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
GATA-1(N6)抗体
目录 :
sc-265
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
N6
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 72
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:1000; 图 2c
Grevet J, Lan X, Hamagami N, Edwards C, Sankaranarayanan L, Ji X, et al. Domain-focused CRISPR screen identifies HRI as a fetal hemoglobin regulator in human erythroid cells. Science. 2018;361:285-290 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5c
Chennupati V, Veiga D, Maslowski K, Andina N, Tardivel A, Yu E, et al. Ribonuclease inhibitor 1 regulates erythropoiesis by controlling GATA1 translation. J Clin Invest. 2018;128:1597-1614 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 7
Saatcioglu H, Cuevas I, Castrillon D. Control of Oocyte Reawakening by Kit. PLoS Genet. 2016;12:e1006215 pubmed 出版商
  • 免疫细胞化学; 小鼠; 8 ug/ml; 图 3b
Hoppe P, Schwarzfischer M, Loeffler D, Kokkaliaris K, Hilsenbeck O, Moritz N, et al. Early myeloid lineage choice is not initiated by random PU.1 to GATA1 protein ratios. Nature. 2016;535:299-302 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 1
  • 免疫印迹; 人类; 图 s1b
  • 染色质免疫沉淀 ; 小鼠; 图 5a
Burda P, Vargova J, Curik N, Salek C, Papadopoulos G, Strouboulis J, et al. GATA-1 Inhibits PU.1 Gene via DNA and Histone H3K9 Methylation of Its Distal Enhancer in Erythroleukemia. PLoS ONE. 2016;11:e0152234 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 7
Minas T, Han J, Javaheri T, Hong S, Schlederer M, SaygideÄŸer Kont Y, et al. YK-4-279 effectively antagonizes EWS-FLI1 induced leukemia in a transgenic mouse model. Oncotarget. 2015;6:37678-94 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2b
Yashiro T, Kubo M, Ogawa H, Okumura K, Nishiyama C. PU.1 Suppresses Th2 Cytokine Expression via Silencing of GATA3 Transcription in Dendritic Cells. PLoS ONE. 2015;10:e0137699 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Krivega I, Byrnes C, de Vasconcellos J, Lee Y, Kaushal M, Dean A, et al. Inhibition of G9a methyltransferase stimulates fetal hemoglobin production by facilitating LCR/γ-globin looping. Blood. 2015;126:665-72 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 4,5,6
Stonestrom A, Hsu S, Jahn K, Huang P, Keller C, Giardine B, et al. Functions of BET proteins in erythroid gene expression. Blood. 2015;125:2825-34 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Moriguchi T, Suzuki M, Yu L, Takai J, Ohneda K, Yamamoto M. Progenitor stage-specific activity of a cis-acting double GATA motif for Gata1 gene expression. Mol Cell Biol. 2015;35:805-15 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200
Weston W, Zayas J, Perez R, George J, Jurecic R. Dynamic equilibrium of heterogeneous and interconvertible multipotent hematopoietic cell subsets. Sci Rep. 2014;4:5199 pubmed 出版商
  • 免疫印迹; 大鼠
  • 染色质免疫沉淀 ; 小鼠
Ohmori S, Takai J, Ishijima Y, Suzuki M, Moriguchi T, Philipsen S, et al. Regulation of GATA factor expression is distinct between erythroid and mast cell lineages. Mol Cell Biol. 2012;32:4742-55 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5c
Yang Y, Ahn Y, Gibbons D, Zang Y, Lin W, Thilaganathan N, et al. The Notch ligand Jagged2 promotes lung adenocarcinoma metastasis through a miR-200-dependent pathway in mice. J Clin Invest. 2011;121:1373-85 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Steger D, Lefterova M, Ying L, Stonestrom A, Schupp M, Zhuo D, et al. DOT1L/KMT4 recruitment and H3K79 methylation are ubiquitously coupled with gene transcription in mammalian cells. Mol Cell Biol. 2008;28:2825-39 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • EMSA; 人类
De Gobbi M, Viprakasit V, Hughes J, Fisher C, Buckle V, Ayyub H, et al. A regulatory SNP causes a human genetic disease by creating a new transcriptional promoter. Science. 2006;312:1215-7 pubmed
Ortiz Rivero S, Baquero C, Hernández Cano L, Roldán Etcheverry J, Gutiérrez Herrero S, Fernández Infante C, et al. C3G, through its GEF activity, induces megakaryocytic differentiation and proplatelet formation. Cell Commun Signal. 2018;16:101 pubmed 出版商
Shen Y, Bassett M, Gurumurthy A, Nar R, Knudson I, Guy C, et al. Identification of a Novel Enhancer/Chromatin Opening Element Associated with High-Level γ-Globin Gene Expression. Mol Cell Biol. 2018;38: pubmed 出版商
Ioannou M, Papageorgiou D, Ogryzko V, Strouboulis J. Mammalian expression vectors for metabolic biotinylation tandem affinity tagging by co-expression in cis of a mammalian codon-optimized BirA biotin ligase. BMC Res Notes. 2018;11:390 pubmed 出版商
García Carpizo V, Ruiz Llorente S, Sarmentero J, Graña Castro O, Pisano D, Barrero M. CREBBP/EP300 bromodomains are critical to sustain the GATA1/MYC regulatory axis in proliferation. Epigenetics Chromatin. 2018;11:30 pubmed 出版商
Tusi B, Wolock S, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, et al. Population snapshots predict early haematopoietic and erythroid hierarchies. Nature. 2018;555:54-60 pubmed 出版商
Minkina A, Lindeman R, Gearhart M, Chassot A, Chaboissier M, Ghyselinck N, et al. Retinoic acid signaling is dispensable for somatic development and function in the mammalian ovary. Dev Biol. 2017;424:208-220 pubmed 出版商
Mendoza Parra M, Saravaki V, Cholley P, Blum M, Billoré B, Gronemeyer H. Antibody performance in ChIP-sequencing assays: From quality scores of public data sets to quantitative certification. F1000Res. 2016;5:54 pubmed 出版商
Meinders M, Hoogenboezem M, Scheenstra M, De Cuyper I, Papadopoulos P, Nemeth T, et al. Repercussion of Megakaryocyte-Specific Gata1 Loss on Megakaryopoiesis and the Hematopoietic Precursor Compartment. PLoS ONE. 2016;11:e0154342 pubmed 出版商
Gely Pernot A, Hao C, Becker E, Stuparevic I, Kervarrec C, Chalmel F, et al. The epigenetic processes of meiosis in male mice are broadly affected by the widely used herbicide atrazine. BMC Genomics. 2015;16:885 pubmed 出版商
Amanatiadou E, Papadopoulos G, Strouboulis J, Vizirianakis I. GATA1 and PU.1 Bind to Ribosomal Protein Genes in Erythroid Cells: Implications for Ribosomopathies. PLoS ONE. 2015;10:e0140077 pubmed 出版商
French C, Ye F, Revetta F, Zhang B, Coffey R, Washington M, et al. Linking patient outcome to high throughput protein expression data identifies novel regulators of colorectal adenocarcinoma aggressiveness. F1000Res. 2015;4:99 pubmed 出版商
Papageorgiou D, Demmers J, Strouboulis J. NP-40 reduces contamination by endogenous biotinylated carboxylases during purification of biotin tagged nuclear proteins. Protein Expr Purif. 2013;89:80-3 pubmed 出版商
Su M, Steiner L, Bogardus H, Mishra T, Schulz V, Hardison R, et al. Identification of biologically relevant enhancers in human erythroid cells. J Biol Chem. 2013;288:8433-44 pubmed 出版商
Lavery R, Chassot A, Pauper E, Gregoire E, Klopfenstein M, de Rooij D, et al. Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals. PLoS Genet. 2012;8:e1003170 pubmed 出版商
Costa F, Fedosyuk H, Chazelle A, Neades R, Peterson K. Mi2? is required for ?-globin gene silencing: temporal assembly of a GATA-1-FOG-1-Mi2 repressor complex in ?-YAC transgenic mice. PLoS Genet. 2012;8:e1003155 pubmed 出版商
Yocum A, Steiner L, Seidel N, Cline A, Rout E, Lin J, et al. A tissue-specific chromatin loop activates the erythroid ankyrin-1 promoter. Blood. 2012;120:3586-93 pubmed 出版商
Kang H, Voleti B, Hajszan T, Rajkowska G, Stockmeier C, Licznerski P, et al. Decreased expression of synapse-related genes and loss of synapses in major depressive disorder. Nat Med. 2012;18:1413-7 pubmed
Baba Y, Maeda K, Yashiro T, Inage E, Kasakura K, Suzuki R, et al. GATA2 is a critical transactivator for the human IL1RL1/ST2 promoter in mast cells/basophils: opposing roles for GATA2 and GATA1 in human IL1RL1/ST2 gene expression. J Biol Chem. 2012;287:32689-96 pubmed
Pellegrino J, Castrillon D, David G. Chromatin associated Sin3A is essential for male germ cell lineage in the mouse. Dev Biol. 2012;369:349-55 pubmed 出版商
Thiaville M, Stoeck A, Chen L, Wu R, Magnani L, Oidtman J, et al. Identification of PBX1 target genes in cancer cells by global mapping of PBX1 binding sites. PLoS ONE. 2012;7:e36054 pubmed 出版商
Kang Y, Sanalkumar R, O Geen H, Linnemann A, Chang C, Bouhassira E, et al. Autophagy driven by a master regulator of hematopoiesis. Mol Cell Biol. 2012;32:226-39 pubmed 出版商
Bonello G, Pham M, Begum K, Sigala J, Sataranatarajan K, Mummidi S. An evolutionarily conserved TNF-alpha-responsive enhancer in the far upstream region of human CCL2 locus influences its gene expression. J Immunol. 2011;186:7025-38 pubmed 出版商
Weider K, Bergmann M, Giese S, Guillou F, Failing K, Brehm R. Altered differentiation and clustering of Sertoli cells in transgenic mice showing a Sertoli cell specific knockout of the connexin 43 gene. Differentiation. 2011;82:38-49 pubmed 出版商
Zhou J, Pan J, Eckardt S, Leu N, McLaughlin K, Wang P. Nxf3 is expressed in Sertoli cells, but is dispensable for spermatogenesis. Mol Reprod Dev. 2011;78:241-9 pubmed 出版商
Amigo J, Yu M, Troadec M, Gwynn B, Cooney J, Lambert A, et al. Identification of distal cis-regulatory elements at mouse mitoferrin loci using zebrafish transgenesis. Mol Cell Biol. 2011;31:1344-56 pubmed 出版商
Guo Wei Z, Rui Feng Y, Xiang L, Mitchell W, De Pei L, Chih Chuan L. NF-E2: a novel regulator of alpha-hemoglobin stabilizing protein gene expression. Chin Med Sci J. 2010;25:193-8 pubmed
Cantù C, Grande V, Alborelli I, Cassinelli L, Cantù I, Colzani M, et al. A highly conserved SOX6 double binding site mediates SOX6 gene downregulation in erythroid cells. Nucleic Acids Res. 2011;39:486-501 pubmed 出版商
Snow J, Kim J, Currie C, Xu J, Orkin S. Sumoylation regulates interaction of FOG1 with C-terminal-binding protein (CTBP). J Biol Chem. 2010;285:28064-75 pubmed 出版商
Kong K, Owens K, Rogers J, Mullenix J, Velu C, Grimes H, et al. MIR-23A microRNA cluster inhibits B-cell development. Exp Hematol. 2010;38:629-640.e1 pubmed 出版商
Hernández A, Villegas A, Anguita E. Human promoter mutations unveil Oct-1 and GATA-1 opposite action on Gfi1b regulation. Ann Hematol. 2010;89:759-65 pubmed 出版商
Chen R, Chou Y, Lan Y, Huang T, Shen C. Developmental silencing of human zeta-globin gene expression is mediated by the transcriptional repressor RREB1. J Biol Chem. 2010;285:10189-97 pubmed 出版商
Miccio A, Wang Y, Hong W, Gregory G, Wang H, Yu X, et al. NuRD mediates activating and repressive functions of GATA-1 and FOG-1 during blood development. EMBO J. 2010;29:442-56 pubmed 出版商
Burda P, Curik N, Kokavec J, Basova P, Mikulenkova D, Skoultchi A, et al. PU.1 activation relieves GATA-1-mediated repression of Cebpa and Cbfb during leukemia differentiation. Mol Cancer Res. 2009;7:1693-703 pubmed 出版商
Anguita E, Villegas A, Iborra F, Hernández A. GFI1B controls its own expression binding to multiple sites. Haematologica. 2010;95:36-46 pubmed 出版商
Amigo J, Ackermann G, Cope J, Yu M, Cooney J, Ma D, et al. The role and regulation of friend of GATA-1 (FOG-1) during blood development in the zebrafish. Blood. 2009;114:4654-63 pubmed 出版商
Ohneda K, Ohmori S, Ishijima Y, Nakano M, Yamamoto M. Characterization of a functional ZBP-89 binding site that mediates Gata1 gene expression during hematopoietic development. J Biol Chem. 2009;284:30187-99 pubmed 出版商
Steiner L, Maksimova Y, Schulz V, Wong C, Raha D, Mahajan M, et al. Chromatin architecture and transcription factor binding regulate expression of erythrocyte membrane protein genes. Mol Cell Biol. 2009;29:5399-412 pubmed 出版商
Tallack M, Keys J, Humbert P, Perkins A. EKLF/KLF1 controls cell cycle entry via direct regulation of E2f2. J Biol Chem. 2009;284:20966-74 pubmed 出版商
Furuhata A, Murakami M, Ito H, Gao S, Yoshida K, Sobue S, et al. GATA-1 and GATA-2 binding to 3' enhancer of WT1 gene is essential for its transcription in acute leukemia and solid tumor cell lines. Leukemia. 2009;23:1270-7 pubmed 出版商
Samuels A, Klinken S, Ingley E. Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation. Blood. 2009;113:3845-56 pubmed 出版商
Di L, Wang L, Zhou G, Wu X, Guo Z, Ke X, et al. Identification of long range regulatory elements of mouse alpha-globin gene cluster by quantitative associated chromatin trap (QACT). J Cell Biochem. 2008;105:301-12 pubmed 出版商
Aispuru G, Aguirre M, Aquino Esperanza J, Lettieri C, Juaristi J, Brandan N. Erythroid expansion and survival in response to acute anemia stress: the role of EPO receptor, GATA-1, Bcl-xL and caspase-3. Cell Biol Int. 2008;32:966-78 pubmed 出版商
Pina C, May G, Soneji S, Hong D, Enver T. MLLT3 regulates early human erythroid and megakaryocytic cell fate. Cell Stem Cell. 2008;2:264-73 pubmed 出版商
Du M, Lv X, Hao D, Zhao G, Wu X, Wu F, et al. MafK/NF-E2 p18 is required for beta-globin genes activation by mediating the proximity of LCR and active beta-globin genes in MEL cell line. Int J Biochem Cell Biol. 2008;40:1481-93 pubmed 出版商
Palstra R, Simonis M, Klous P, Brasset E, Eijkelkamp B, de Laat W. Maintenance of long-range DNA interactions after inhibition of ongoing RNA polymerase II transcription. PLoS ONE. 2008;3:e1661 pubmed 出版商
Ghinassi B, Verrucci M, Jelicic K, Di Noia A, Migliaccio G, Migliaccio A. Interleukin-3 and erythropoietin cooperate in the regulation of the expression of erythroid-specific transcription factors during erythroid differentiation. Exp Hematol. 2007;35:735-47 pubmed
Kim S, Bardwell V, Zarkower D. Cell type-autonomous and non-autonomous requirements for Dmrt1 in postnatal testis differentiation. Dev Biol. 2007;307:314-27 pubmed
Kim S, Namekawa S, Niswander L, Ward J, Lee J, Bardwell V, et al. A mammal-specific Doublesex homolog associates with male sex chromatin and is required for male meiosis. PLoS Genet. 2007;3:e62 pubmed
Layon M, Ackley C, West R, Lowrey C. Expression of GATA-1 in a non-hematopoietic cell line induces beta-globin locus control region chromatin structure remodeling and an erythroid pattern of gene expression. J Mol Biol. 2007;366:737-44 pubmed
Vernet N, Dennefeld C, Guillou F, Chambon P, Ghyselinck N, Mark M. Prepubertal testis development relies on retinoic acid but not rexinoid receptors in Sertoli cells. EMBO J. 2006;25:5816-25 pubmed
Keys J, Tallack M, Hodge D, Cridland S, David R, Perkins A. Genomic organisation and regulation of murine alpha haemoglobin stabilising protein by erythroid Kruppel-like factor. Br J Haematol. 2007;136:150-7 pubmed
Karur V, Lowell C, Besmer P, Agosti V, Wojchowski D. Lyn kinase promotes erythroblast expansion and late-stage development. Blood. 2006;108:1524-32 pubmed
Suh H, Gooya J, Renn K, Friedman A, Johnson P, Keller J. C/EBPalpha determines hematopoietic cell fate in multipotential progenitor cells by inhibiting erythroid differentiation and inducing myeloid differentiation. Blood. 2006;107:4308-16 pubmed
Gutierrez L, Lindeboom F, Ferreira R, Drissen R, Grosveld F, Whyatt D, et al. A hanging drop culture method to study terminal erythroid differentiation. Exp Hematol. 2005;33:1083-91 pubmed
Hong W, Nakazawa M, Chen Y, Kori R, Vakoc C, Rakowski C, et al. FOG-1 recruits the NuRD repressor complex to mediate transcriptional repression by GATA-1. EMBO J. 2005;24:2367-78 pubmed
Ingley E, McCarthy D, Pore J, Sarna M, Adenan A, Wright M, et al. Lyn deficiency reduces GATA-1, EKLF and STAT5, and induces extramedullary stress erythropoiesis. Oncogene. 2005;24:336-43 pubmed
Martowicz M, Grass J, Boyer M, Guend H, Bresnick E. Dynamic GATA factor interplay at a multicomponent regulatory region of the GATA-2 locus. J Biol Chem. 2005;280:1724-32 pubmed
产品信息
产品名称 :
GATA-1(N6)抗体
基因名称 :
GATA1
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-265
类型 :
单克隆
宿主 :
大鼠单克隆
抗原 :
GATA-1
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P)
表位 :
FL(小鼠)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。