产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
GATA-3(HG3-31)抗体
目录 :
sc-268
规格 :
200微克/毫升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
HG3-31
反应物种 :
African green monkey, 人类, 小鼠, 大鼠,
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, 免疫组化-冰冻切片, ChIP-Seq
更多信息或购买 :
文章摘录数: 83
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:100; 图 2a
Buchrieser J, Degrelle S, Couderc T, Nevers Q, Disson O, Manet C, et al. IFITM proteins inhibit placental syncytiotrophoblast formation and promote fetal demise. Science. 2019;365:176-180 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 4a
Kim J, Villadsen R. Expression of Luminal Progenitor Marker CD117 in the Human Breast Gland. J Histochem Cytochem. 2018;66:879-888 pubmed 出版商
  • 免疫沉淀; 人类; 图 4a
Krendl C, Shaposhnikov D, Rishko V, Ori C, Ziegenhain C, Sass S, et al. GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency. Proc Natl Acad Sci U S A. 2017;114:E9579-E9588 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2d
Fell S, Li S, Wallis K, Kock A, Surova O, Rraklli V, et al. Neuroblast differentiation during development and in neuroblastoma requires KIF1B?-mediated transport of TRKA. Genes Dev. 2017;31:1036-1053 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 s5
Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, et al. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017;169:243-257.e25 pubmed 出版商
  • ChIP-Seq; 人类; 图 7
Van de Walle I, Dolens A, Durinck K, De Mulder K, Van Loocke W, Damle S, et al. GATA3 induces human T-cell commitment by restraining Notch activity and repressing NK-cell fate. Nat Commun. 2016;7:11171 pubmed 出版商
  • 免疫组化-石蜡切片; African green monkey; 1:50; 图 5a
Dewi F, Wood C, Willson C, Register T, Lees C, Howard T, et al. Effects of Pubertal Exposure to Dietary Soy on Estrogen Receptor Activity in the Breast of Cynomolgus Macaques. Cancer Prev Res (Phila). 2016;9:385-95 pubmed 出版商
  • 免疫组化; 人类; 1:25; 图 s2
Fridriksdottir A, Kim J, Villadsen R, Klitgaard M, Hopkinson B, Petersen O, et al. Propagation of oestrogen receptor-positive and oestrogen-responsive normal human breast cells in culture. Nat Commun. 2015;6:8786 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 7b
O Brien T, Bao K, Dell aringa M, Ang W, Abraham S, Reinhardt R. Cytokine expression by invariant natural killer T cells is tightly regulated throughout development and settings of type-2 inflammation. Mucosal Immunol. 2016;9:597-609 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Baraut J, Farge D, Jean Louis F, Masse I, Grigore E, Arruda L, et al. Transforming growth factor-β increases interleukin-13 synthesis via GATA-3 transcription factor in T-lymphocytes from patients with systemic sclerosis. Arthritis Res Ther. 2015;17:196 pubmed 出版商
  • 免疫印迹; 小鼠
Bruchard M, Rebé C, Derangère V, Togbé D, Ryffel B, Boidot R, et al. The receptor NLRP3 is a transcriptional regulator of TH2 differentiation. Nat Immunol. 2015;16:859-70 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 4
Castiglioni A, Corna G, Rigamonti E, Basso V, Vezzoli M, Monno A, et al. FOXP3+ T Cells Recruited to Sites of Sterile Skeletal Muscle Injury Regulate the Fate of Satellite Cells and Guide Effective Tissue Regeneration. PLoS ONE. 2015;10:e0128094 pubmed 出版商
  • 免疫组化; 人类
Gromova I, Gromov P, Honma N, Kumar S, Rimm D, Talman M, et al. High level PHGDH expression in breast is predominantly associated with keratin 5-positive cell lineage independently of malignancy. Mol Oncol. 2015;9:1636-54 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1,2,3,4,5,6
Izzo F, Mercogliano F, Venturutti L, Tkach M, Inurrigarro G, Schillaci R, et al. Progesterone receptor activation downregulates GATA3 by transcriptional repression and increased protein turnover promoting breast tumor growth. Breast Cancer Res. 2014;16:491 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Nguyen D, Ouyang H, Mao J, Hlatky L, Barcellos Hoff M. Distinct luminal-type mammary carcinomas arise from orthotopic Trp53-null mammary transplantation of juvenile versus adult mice. Cancer Res. 2014;74:7149-58 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:50
Prakash A, Udager A, Saenz D, Gumucio D. Roles for Nkx2-5 and Gata3 in the ontogeny of the murine smooth muscle gastric ligaments. Am J Physiol Gastrointest Liver Physiol. 2014;307:G430-6 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Godde N, Sheridan J, Smith L, Pearson H, Britt K, Galea R, et al. Scribble modulates the MAPK/Fra1 pathway to disrupt luminal and ductal integrity and suppress tumour formation in the mammary gland. PLoS Genet. 2014;10:e1004323 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠
Kitagawa K, Shibata K, Matsumoto A, Matsumoto M, Ohhata T, Nakayama K, et al. Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development. Mol Cell Biol. 2014;34:2732-44 pubmed
  • 免疫组化-石蜡切片; 人类; 1:100
Ordonez N, Sahin A. Diagnostic utility of immunohistochemistry in distinguishing between epithelioid pleural mesotheliomas and breast carcinomas: a comparative study. Hum Pathol. 2014;45:1529-40 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Zou M, Cao J, Liu Z, Huh S, Polyak K, Yan Q. Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes. J Biol Chem. 2014;289:17620-33 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Li Y, Pan J, Wei C, Chen J, Liu Y, Liu J, et al. LIM homeodomain transcription factor Isl1 directs normal pyloric development by targeting Gata3. BMC Biol. 2014;12:25 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250
  • 免疫组化; 人类; 1:250
Balk Møller E, Kim J, Hopkinson B, Timmermans Wielenga V, Petersen O, Villadsen R. A marker of endocrine receptor-positive cells, CEACAM6, is shared by two major classes of breast cancer: luminal and HER2-enriched. Am J Pathol. 2014;184:1198-208 pubmed 出版商
  • 免疫印迹; 人类
Cyr A, Kulak M, Park J, Bogachek M, Spanheimer P, Woodfield G, et al. TFAP2C governs the luminal epithelial phenotype in mammary development and carcinogenesis. Oncogene. 2015;34:436-44 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Shan L, Li X, Liu L, Ding X, Wang Q, Zheng Y, et al. GATA3 cooperates with PARP1 to regulate CCND1 transcription through modulating histone H1 incorporation. Oncogene. 2014;33:3205-16 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠
Schang A, Granger A, Querat B, Bleux C, Cohen Tannoudji J, Laverrière J. GATA2-induced silencing and LIM-homeodomain protein-induced activation are mediated by a bi-functional response element in the rat GnRH receptor gene. Mol Endocrinol. 2013;27:74-91 pubmed 出版商
  • 免疫组化-石蜡切片; 鸡; 1:100
Jones J, Warchol M. Expression of the Gata3 transcription factor in the acoustic ganglion of the developing avian inner ear. J Comp Neurol. 2009;516:507-18 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Albergaria A, Paredes J, Sousa B, Milanezi F, Carneiro V, Bastos J, et al. Expression of FOXA1 and GATA-3 in breast cancer: the prognostic significance in hormone receptor-negative tumours. Breast Cancer Res. 2009;11:R40 pubmed 出版商
  • 免疫组化; 鸡; 1:200
Warchol M, Speck J. Expression of GATA3 and tenascin in the avian vestibular maculae: normative patterns and changes during sensory regeneration. J Comp Neurol. 2007;500:646-57 pubmed
Hertweck A, Vila de Mucha M, Barber P, Dagil R, Porter H, Ramos A, et al. The TH1 cell lineage-determining transcription factor T-bet suppresses TH2 gene expression by redistributing GATA3 away from TH2 genes. Nucleic Acids Res. 2022;50:4557-4573 pubmed 出版商
Naik A, Byrd A, Lucander A, Krangel M. Hierarchical assembly and disassembly of a transcriptionally active RAG locus in CD4+CD8+ thymocytes. J Exp Med. 2019;216:231-243 pubmed 出版商
Li H, Zhao C, Xu J, Xu Y, Cheng C, Liu Y, et al. Rapid generation of gene-targeted EPS-derived mouse models through tetraploid complementation. Protein Cell. 2019;10:20-30 pubmed 出版商
Yamamoto T, Endo Y, Onodera A, Hirahara K, Asou H, Nakajima T, et al. DUSP10 constrains innate IL-33-mediated cytokine production in ST2hi memory-type pathogenic Th2 cells. Nat Commun. 2018;9:4231 pubmed 出版商
Sada A, Jain P, Wang S, Leung E, Tumbar T. Slc1a3-CreER as a Targeting Tool for the K6+ Epithelial Stem Cell Niche and its Precursors during Mouse Hair Follicle Cycle. J Invest Dermatol. 2017;137:1569-1571 pubmed 出版商
Li Y, Lu Y, Wang S, Han Z, Zhu F, Ni Y, et al. USP21 prevents the generation of T-helper-1-like Treg cells. Nat Commun. 2016;7:13559 pubmed 出版商
Tam K, Chan P, Zhang W, Law P, Tian Z, Fung Chan G, et al. Identification of a novel distal regulatory element of the human Neuroglobin gene by the chromosome conformation capture approach. Nucleic Acids Res. 2017;45:115-126 pubmed 出版商
Kong S, Kim K, Kim J, Kim M, Lee K, Lee J, et al. The ELK3-GATA3 axis orchestrates invasion and metastasis of breast cancer cells in vitro and in vivo. Oncotarget. 2016;7:65137-65146 pubmed 出版商
Lee J, Tiwari A, Shum V, Mills G, Mancini M, Igoshin O, et al. Unraveling the regulatory connections between two controllers of breast cancer cell fate. Nucleic Acids Res. 2014;42:6839-49 pubmed 出版商
Achim K, Peltopuro P, Lahti L, Tsai H, Zachariah A, Astrand M, et al. The role of Tal2 and Tal1 in the differentiation of midbrain GABAergic neuron precursors. Biol Open. 2013;2:990-7 pubmed 出版商
Francius C, Harris A, Rucchin V, Hendricks T, Stam F, Barber M, et al. Identification of multiple subsets of ventral interneurons and differential distribution along the rostrocaudal axis of the developing spinal cord. PLoS ONE. 2013;8:e70325 pubmed 出版商
Gaughan L, Stockley J, Coffey K, O Neill D, Jones D, Wade M, et al. KDM4B is a master regulator of the estrogen receptor signalling cascade. Nucleic Acids Res. 2013;41:6892-904 pubmed 出版商
Nautiyal J, Steel J, Mane M, Oduwole O, Poliandri A, Alexi X, et al. The transcriptional co-factor RIP140 regulates mammary gland development by promoting the generation of key mitogenic signals. Development. 2013;140:1079-89 pubmed 出版商
Muroi S, Tanaka H, Miyamoto C, Taniuchi I. Cutting edge: fine-tuning of Thpok gene activation by an enhancer in close proximity to its own silencer. J Immunol. 2013;190:1397-401 pubmed 出版商
Lahti L, Achim K, Partanen J. Molecular regulation of GABAergic neuron differentiation and diversity in the developing midbrain. Acta Physiol (Oxf). 2013;207:616-27 pubmed 出版商
Virolainen S, Achim K, Peltopuro P, Salminen M, Partanen J. Transcriptional regulatory mechanisms underlying the GABAergic neuron fate in different diencephalic prosomeres. Development. 2012;139:3795-805 pubmed
Frietze S, Wang R, Yao L, Tak Y, Ye Z, Gaddis M, et al. Cell type-specific binding patterns reveal that TCF7L2 can be tethered to the genome by association with GATA3. Genome Biol. 2012;13:R52 pubmed 出版商
Liu H, Shi J, Wilkerson M, Lin F. Immunohistochemical evaluation of GATA3 expression in tumors and normal tissues: a useful immunomarker for breast and urothelial carcinomas. Am J Clin Pathol. 2012;138:57-64 pubmed 出版商
Achim K, Peltopuro P, Lahti L, Li J, Salminen M, Partanen J. Distinct developmental origins and regulatory mechanisms for GABAergic neurons associated with dopaminergic nuclei in the ventral mesodiencephalic region. Development. 2012;139:2360-70 pubmed 出版商
Oliver C, Khaled W, Frend H, Nichols J, Watson C. The Stat6-regulated KRAB domain zinc finger protein Zfp157 regulates the balance of lineages in mammary glands and compensates for loss of Gata-3. Genes Dev. 2012;26:1086-97 pubmed 出版商
Zhao X, Malhotra G, Band H, Band V. Derivation of myoepithelial progenitor cells from bipotent mammary stem/progenitor cells. PLoS ONE. 2012;7:e35338 pubmed 出版商
Quesne J, Jones J, Warren J, Dawson S, Ali H, Bardwell H, et al. Biological and prognostic associations of miR-205 and let-7b in breast cancer revealed by in situ hybridization analysis of micro-RNA expression in arrays of archival tumour tissue. J Pathol. 2012;227:306-14 pubmed 出版商
Sogut A, Yilmaz O, Kirmaz C, Ozbilgin K, Onur E, Celik O, et al. Regulatory-T, T-helper 1, and T-helper 2 cell differentiation in nasal mucosa of allergic rhinitis with olive pollen sensitivity. Int Arch Allergy Immunol. 2012;157:349-53 pubmed 出版商
Nakahira M, Nakanishi K. Requirement of GATA-binding protein 3 for II13 gene expression in IL-18-stimulated Th1 cells. Int Immunol. 2011;23:761-72 pubmed 出版商
Asselin Labat M, Sutherland K, Vaillant F, Gyorki D, Wu D, Holroyd S, et al. Gata-3 negatively regulates the tumor-initiating capacity of mammary luminal progenitor cells and targets the putative tumor suppressor caspase-14. Mol Cell Biol. 2011;31:4609-22 pubmed 出版商
Hwang S, Kim K, Lee G. Defective GATA-3 expression in Th2 LCR-deficient mice. Biochem Biophys Res Commun. 2011;410:866-71 pubmed 出版商
Jacob E, Hod Dvorai R, Ben Mordechai O, Boyko Y, Avni O. Dual function of polycomb group proteins in differentiated murine T helper (CD4+) cells. J Mol Signal. 2011;6:5 pubmed 出版商
Kirmaz C, Ozenturk Kirgiz O, Bayrak P, Yilmaz O, Vatansever S, Ozbilgin K, et al. Effects of allergen-specific immunotherapy on functions of helper and regulatory T cells in patients with seasonal allergic rhinitis. Eur Cytokine Netw. 2011;22:15-23 pubmed 出版商
Affara M, Dunmore B, Sanders D, Johnson N, Print C, Charnock Jones D. MMP1 bimodal expression and differential response to inflammatory mediators is linked to promoter polymorphisms. BMC Genomics. 2011;12:43 pubmed 出版商
Yoon N, Maresh E, Shen D, Elshimali Y, Apple S, Horvath S, et al. Higher levels of GATA3 predict better survival in women with breast cancer. Hum Pathol. 2010;41:1794-801 pubmed 出版商
Stanelle J, Döring C, Hansmann M, Kuppers R. Mechanisms of aberrant GATA3 expression in classical Hodgkin lymphoma and its consequences for the cytokine profile of Hodgkin and Reed/Sternberg cells. Blood. 2010;116:4202-11 pubmed 出版商
Hwang S, Lee S, Lee W, Lee G. GATA-binding protein-3 regulates T helper type 2 cytokine and ifng loci through interaction with metastasis-associated protein 2. Immunology. 2010;131:50-8 pubmed 出版商
Gross J, Stute K, Moller R, Fuchs J, Amarjargal N, Pohl E, et al. Expression of prestin and Gata-3,-2,-1 mRNA in the rat organ of Corti during the postnatal period and in culture. Hear Res. 2010;261:9-21 pubmed 出版商
Xu M, Tan C, Zhou J, Huang X, Dai Z, Zhu H, et al. The dynamic changes of T-bet(+)/GATA-3(+) and RORgammat(+)/FOXP3(+) cells in recipient spleens and grafts after rat orthotopic liver transplantation. Transpl Immunol. 2010;22:165-71 pubmed 出版商
Bonin F, Molina M, Malet C, Ginestet C, Berthier Vergnes O, Martin M, et al. GATA3 is a master regulator of the transcriptional response to low-dose ionizing radiation in human keratinocytes. BMC Genomics. 2009;10:417 pubmed 出版商
Kakuta Y, Ueki N, Kinouchi Y, Negoro K, Endo K, Nomura E, et al. TNFSF15 transcripts from risk haplotype for Crohn's disease are overexpressed in stimulated T cells. Hum Mol Genet. 2009;18:1089-98 pubmed 出版商
Ong C, Sedy J, Murphy K, Kopan R. Notch and presenilin regulate cellular expansion and cytokine secretion but cannot instruct Th1/Th2 fate acquisition. PLoS ONE. 2008;3:e2823 pubmed 出版商
Engelsen I, Stefansson I, Akslen L, Salvesen H. GATA3 expression in estrogen receptor alpha-negative endometrial carcinomas identifies aggressive tumors with high proliferation and poor patient survival. Am J Obstet Gynecol. 2008;199:543.e1-7 pubmed 出版商
Sihto H, Lundin J, Lehtimäki T, Sarlomo Rikala M, Butzow R, Holli K, et al. Molecular subtypes of breast cancers detected in mammography screening and outside of screening. Clin Cancer Res. 2008;14:4103-10 pubmed 出版商
Thompson M, Lapointe J, Choi Y, Ong D, Higgins J, Brooks J, et al. Identification of candidate prostate cancer genes through comparative expression-profiling of seminal vesicle. Prostate. 2008;68:1248-56 pubmed 出版商
Chang W, Lin Z, Kulessa H, Hebert J, Hogan B, Wu D. Bmp4 is essential for the formation of the vestibular apparatus that detects angular head movements. PLoS Genet. 2008;4:e1000050 pubmed 出版商
Daniel C, Sartory N, Zahn N, Radeke H, Stein J. Immune modulatory treatment of trinitrobenzene sulfonic acid colitis with calcitriol is associated with a change of a T helper (Th) 1/Th17 to a Th2 and regulatory T cell profile. J Pharmacol Exp Ther. 2008;324:23-33 pubmed
Zeiser R, Youssef S, Baker J, Kambham N, Steinman L, Negrin R. Preemptive HMG-CoA reductase inhibition provides graft-versus-host disease protection by Th-2 polarization while sparing graft-versus-leukemia activity. Blood. 2007;110:4588-98 pubmed
Naoe Y, Setoguchi R, Akiyama K, Muroi S, Kuroda M, Hatam F, et al. Repression of interleukin-4 in T helper type 1 cells by Runx/Cbf beta binding to the Il4 silencer. J Exp Med. 2007;204:1749-55 pubmed
Charafe Jauffret E, Monville F, Bertucci F, Esterni B, Ginestier C, Finetti P, et al. Moesin expression is a marker of basal breast carcinomas. Int J Cancer. 2007;121:1779-85 pubmed
Birmingham N, Parvataneni S, Hassan H, Harkema J, Samineni S, Navuluri L, et al. An adjuvant-free mouse model of tree nut allergy using hazelnut as a model tree nut. Int Arch Allergy Immunol. 2007;144:203-10 pubmed
Lund R, Löytömäki M, Naumanen T, Dixon C, Chen Z, Ahlfors H, et al. Genome-wide identification of novel genes involved in early Th1 and Th2 cell differentiation. J Immunol. 2007;178:3648-60 pubmed
Layon M, Ackley C, West R, Lowrey C. Expression of GATA-1 in a non-hematopoietic cell line induces beta-globin locus control region chromatin structure remodeling and an erythroid pattern of gene expression. J Mol Biol. 2007;366:737-44 pubmed
Abba M, Nunez M, Colussi A, Croce M, Segal Eiras A, Aldaz C. GATA3 protein as a MUC1 transcriptional regulator in breast cancer cells. Breast Cancer Res. 2006;8:R64 pubmed
Bertucci F, Finetti P, Cervera N, Charafe Jauffret E, Mamessier E, Adélaïde J, et al. Gene expression profiling shows medullary breast cancer is a subgroup of basal breast cancers. Cancer Res. 2006;66:4636-44 pubmed
Dunn S, Youssef S, Goldstein M, Prod homme T, Weber M, Zamvil S, et al. Isoprenoids determine Th1/Th2 fate in pathogenic T cells, providing a mechanism of modulation of autoimmunity by atorvastatin. J Exp Med. 2006;203:401-12 pubmed
Yamane H, Zhu J, Paul W. Independent roles for IL-2 and GATA-3 in stimulating naive CD4+ T cells to generate a Th2-inducing cytokine environment. J Exp Med. 2005;202:793-804 pubmed
Bocek P, Foucras G, Paul W. Interferon gamma enhances both in vitro and in vivo priming of CD4+ T cells for IL-4 production. J Exp Med. 2004;199:1619-30 pubmed
Komine O, Hayashi K, Natsume W, Watanabe T, Seki Y, Seki N, et al. The Runx1 transcription factor inhibits the differentiation of naive CD4+ T cells into the Th2 lineage by repressing GATA3 expression. J Exp Med. 2003;198:51-61 pubmed
Zhou M, Ouyang W, Gong Q, Katz S, White J, Orkin S, et al. Friend of GATA-1 represses GATA-3-dependent activity in CD4+ T cells. J Exp Med. 2001;194:1461-71 pubmed
产品信息
产品名称 :
GATA-3(HG3-31)抗体
基因名称 :
GATA3
规格 :
200微克/毫升
目录号 :
sc-268
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
GATA-3
反应物种 :
m, r, h, avian
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P)
表位 :
N末端(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。