产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
H-Ras (259) Antibody
目录 :
sc-35
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
nonconjugated
克隆名称 :
259
反应物种 :
人类, 小鼠, 大鼠, , 猕猴
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 76
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 猕猴; 图 2
  • 免疫印迹; 猪; 图 2
Simões M, Martins C, Ferreira F. Early intranuclear replication of African swine fever virus genome modifies the landscape of the host cell nucleus. Virus Res. 2015;210:1-7 pubmed 出版商
  • 免疫印迹; 人类
Funes J, Quintero M, Henderson S, Martinez D, Qureshi U, Westwood C, et al. Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production. Proc Natl Acad Sci U S A. 2007;104:6223-8 pubmed
Saha S, Choi H, Kim B, Dayem A, Yang G, Kim K, et al. KRT19 directly interacts with β-catenin/RAC1 complex to regulate NUMB-dependent NOTCH signaling pathway and breast cancer properties. Oncogene. 2017;36:332-349 pubmed 出版商
Zhou M, Wiener H, Su W, Zhou Y, Liot C, Ahearn I, et al. VPS35 binds farnesylated N-Ras in the cytosol to regulate N-Ras trafficking. J Cell Biol. 2016;214:445-58 pubmed 出版商
Fritsch K, Mernberger M, Nist A, Stiewe T, Brehm A, Jacob R. Galectin-3 interacts with components of the nuclear ribonucleoprotein complex. BMC Cancer. 2016;16:502 pubmed 出版商
Ohsaki Y, Kawai T, Yoshikawa Y, Cheng J, Jokitalo E, Fujimoto T. PML isoform II plays a critical role in nuclear lipid droplet formation. J Cell Biol. 2016;212:29-38 pubmed 出版商
McCuaig R, Dunn J, Li J, Masch A, Knaute T, Schutkowski M, et al. PKC-Theta is a Novel SC35 Splicing Factor Regulator in Response to T Cell Activation. Front Immunol. 2015;6:562 pubmed 出版商
Walker E, Jensen L, Croft S, Ghildyal R. Variation in the nuclear effects of infection by different human rhinovirus serotypes. Front Microbiol. 2015;6:875 pubmed 出版商
Rodríguez Muñoz R, Cárdenas Aguayo M, Alemán V, Osorio B, Chávez González O, Rendon A, et al. Novel Nuclear Protein Complexes of Dystrophin 71 Isoforms in Rat Cultured Hippocampal GABAergic and Glutamatergic Neurons. PLoS ONE. 2015;10:e0137328 pubmed 出版商
Stockley J, Markert E, Zhou Y, Robson C, Elliott D, Lindberg J, et al. The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7. Sci Rep. 2015;5:13426 pubmed 出版商
Schraivogel D, Schindler S, Danner J, Kremmer E, Pfaff J, Hannus S, et al. Importin-β facilitates nuclear import of human GW proteins and balances cytoplasmic gene silencing protein levels. Nucleic Acids Res. 2015;43:7447-61 pubmed 出版商
Díaz Hernández J, Sebastián Serrano Ã, Gómez Villafuertes R, Díaz Hernández M, Miras Portugal M. Age-related nuclear translocation of P2X6 subunit modifies splicing activity interacting with splicing factor 3A1. PLoS ONE. 2015;10:e0123121 pubmed 出版商
Chang S, Chang W, Lu C, Tarn W. Alanine repeats influence protein localization in splicing speckles and paraspeckles. Nucleic Acids Res. 2014;42:13788-98 pubmed 出版商
Janardhan S, Marks R, Gajewski T. Primary murine CD4+ T cells fail to acquire the ability to produce effector cytokines when active Ras is present during Th1/Th2 differentiation. PLoS ONE. 2014;9:e112831 pubmed 出版商
Guida M, Maraldi T, Beretti F, Follo M, Manzoli L, De Pol A. Nuclear Nox4-derived reactive oxygen species in myelodysplastic syndromes. Biomed Res Int. 2014;2014:456937 pubmed 出版商
Choudhury R, Roy S, Tsai Y, Tripathy A, Graves L, Wang Z. The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration. Nat Commun. 2014;5:3078 pubmed 出版商
Ping X, Sun B, Wang L, Xiao W, Yang X, Wang W, et al. Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase. Cell Res. 2014;24:177-89 pubmed 出版商
Derlig K, Gießl A, Brandstätter J, Enz R, Dahlhaus R. Identification and characterisation of Simiate, a novel protein linked to the fragile X syndrome. PLoS ONE. 2013;8:e83007 pubmed 出版商
Mbonye U, Gokulrangan G, Datt M, Dobrowolski C, Cooper M, Chance M, et al. Phosphorylation of CDK9 at Ser175 enhances HIV transcription and is a marker of activated P-TEFb in CD4(+) T lymphocytes. PLoS Pathog. 2013;9:e1003338 pubmed 出版商
Vivarelli S, Lenzken S, Ruepp M, Ranzini F, Maffioletti A, Alvarez R, et al. Paraquat modulates alternative pre-mRNA splicing by modifying the intracellular distribution of SRPK2. PLoS ONE. 2013;8:e61980 pubmed 出版商
Werwein E, Dzuganova M, Usadel C, Klempnauer K. B-Myb switches from Cyclin/Cdk-dependent to Jnk- and p38 kinase-dependent phosphorylation and associates with SC35 bodies after UV stress. Cell Death Dis. 2013;4:e511 pubmed 出版商
Li S, Guo W, Dewey C, Greaser M. Rbm20 regulates titin alternative splicing as a splicing repressor. Nucleic Acids Res. 2013;41:2659-72 pubmed 出版商
Gu B, Eick D, Bensaude O. CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo. Nucleic Acids Res. 2013;41:1591-603 pubmed 出版商
Tsuiji H, Iguchi Y, Furuya A, Kataoka A, Hatsuta H, Atsuta N, et al. Spliceosome integrity is defective in the motor neuron diseases ALS and SMA. EMBO Mol Med. 2013;5:221-34 pubmed 出版商
Layerenza J, Gonzalez P, García de Bravo M, Polo M, Sisti M, Ves Losada A. Nuclear lipid droplets: a novel nuclear domain. Biochim Biophys Acta. 2013;1831:327-40 pubmed 出版商
Jeong W, Rho J, Yoon Y, Yoo S, Jeong N, Ryu W, et al. Cytoplasmic and nuclear anti-apoptotic roles of ?B-crystallin in retinal pigment epithelial cells. PLoS ONE. 2012;7:e45754 pubmed 出版商
Kumar P, Kumar P, Lindberg L, Thirkill T, Ji J, Martsching L, et al. The MUC1 extracellular domain subunit is found in nuclear speckles and associates with spliceosomes. PLoS ONE. 2012;7:e42712 pubmed 出版商
Kasper S, Breitenbuecher F, Heidel F, Hoffarth S, Markova B, Schuler M, et al. Targeting MCL-1 sensitizes FLT3-ITD-positive leukemias to cytotoxic therapies. Blood Cancer J. 2012;2:e60 pubmed 出版商
Ohnuki H, Inoue H, Takemori N, Nakayama H, Sakaue T, Fukuda S, et al. BAZF, a novel component of cullin3-based E3 ligase complex, mediates VEGFR and Notch cross-signaling in angiogenesis. Blood. 2012;119:2688-98 pubmed 出版商
Janardhan S, Praveen K, Marks R, Gajewski T. Evidence implicating the Ras pathway in multiple CD28 costimulatory functions in CD4+ T cells. PLoS ONE. 2011;6:e24931 pubmed 出版商
Lenos K, de Lange J, Teunisse A, Lodder K, Verlaan de Vries M, Wiercinska E, et al. Oncogenic functions of hMDMX in in vitro transformation of primary human fibroblasts and embryonic retinoblasts. Mol Cancer. 2011;10:111 pubmed 出版商
Puppin C, Passon N, Lavarone E, Di Loreto C, Frasca F, Vella V, et al. Levels of histone acetylation in thyroid tumors. Biochem Biophys Res Commun. 2011;411:679-83 pubmed 出版商
Ballester M, Rodríguez Cariño C, Perez M, Gallardo C, Rodriguez J, Salas M, et al. Disruption of nuclear organization during the initial phase of African swine fever virus infection. J Virol. 2011;85:8263-9 pubmed 出版商
Nagarkatti Gude D, Jaimez R, Henderson S, Teves M, Zhang Z, Strauss J. Spag16, an axonemal central apparatus gene, encodes a male germ cell nuclear speckle protein that regulates SPAG16 mRNA expression. PLoS ONE. 2011;6:e20625 pubmed 出版商
Qian W, Liang H, Shi J, Jin N, Grundke Iqbal I, Iqbal K, et al. Regulation of the alternative splicing of tau exon 10 by SC35 and Dyrk1A. Nucleic Acids Res. 2011;39:6161-71 pubmed 出版商
Dai Y, Walker S, de Vet E, Cook S, Welch H, Lockyer P. Ca2+-dependent monomer and dimer formation switches CAPRI Protein between Ras GTPase-activating protein (GAP) and RapGAP activities. J Biol Chem. 2011;286:19905-16 pubmed 出版商
Harrigan J, Belotserkovskaya R, Coates J, Dimitrova D, Polo S, Bradshaw C, et al. Replication stress induces 53BP1-containing OPT domains in G1 cells. J Cell Biol. 2011;193:97-108 pubmed 出版商
Scharf A, Grozdanov P, Veith R, Kubitscheck U, Meier U, von Mikecz A. Distant positioning of proteasomal proteolysis relative to actively transcribed genes. Nucleic Acids Res. 2011;39:4612-27 pubmed 出版商
Kim Y, Lee J, Oh K, Araki M, Araki K, Yamamura K, et al. NSrp70 is a novel nuclear speckle-related protein that modulates alternative pre-mRNA splicing in vivo. Nucleic Acids Res. 2011;39:4300-14 pubmed 出版商
Sytnikova Y, Kubarenko A, Sch fer A, Weber A, Niehrs C. Gadd45a is an RNA binding protein and is localized in nuclear speckles. PLoS ONE. 2011;6:e14500 pubmed 出版商
Shevtsov S, Dundr M. Nucleation of nuclear bodies by RNA. Nat Cell Biol. 2011;13:167-73 pubmed 出版商
Kaddoum L, Magdeleine E, Waldo G, Joly E, Cabantous S. One-step split GFP staining for sensitive protein detection and localization in mammalian cells. Biotechniques. 2010;49:727-8, 730, 732 passim pubmed 出版商
Belzile J, Abrahamyan L, Gerard F, Rougeau N, Cohen E. Formation of mobile chromatin-associated nuclear foci containing HIV-1 Vpr and VPRBP is critical for the induction of G2 cell cycle arrest. PLoS Pathog. 2010;6:e1001080 pubmed 出版商
Favale N, Fernández Tome M, Pescio L, Sterin Speziale N. The rate-limiting enzyme in phosphatidylcholine synthesis is associated with nuclear speckles under stress conditions. Biochim Biophys Acta. 2010;1801:1184-94 pubmed 出版商
Wang X, He S, Sun J, Delcuve G, Davie J. Selective association of peroxiredoxin 1 with genomic DNA and COX-2 upstream promoter elements in estrogen receptor negative breast cancer cells. Mol Biol Cell. 2010;21:2987-95 pubmed 出版商
Huen M, Sy S, Leung K, Ching Y, Tipoe G, Man C, et al. SON is a spliceosome-associated factor required for mitotic progression. Cell Cycle. 2010;9:2679-85 pubmed 出版商
Ohshiro K, Mudvari P, Meng Q, Rayala S, Sahin A, Fuqua S, et al. Identification of a novel estrogen receptor-alpha variant and its upstream splicing regulator. Mol Endocrinol. 2010;24:914-22 pubmed 出版商
Navaraj A, Finnberg N, Dicker D, Yang W, Matthew E, El Deiry W. Reduced cell death, invasive and angiogenic features conferred by BRCA1-deficiency in mammary epithelial cells transformed with H-Ras. Cancer Biol Ther. 2009;8:2417-44 pubmed
Rajan P, Dalgliesh C, Bourgeois C, Heiner M, Emami K, Clark E, et al. Proteomic identification of heterogeneous nuclear ribonucleoprotein L as a novel component of SLM/Sam68 Nuclear Bodies. BMC Cell Biol. 2009;10:82 pubmed 出版商
Moumtzi S, Roberts M, Joyce T, Evangelidou M, Probert L, Frillingos S, et al. Gene expression profile associated with oncogenic ras-induced senescence, cell death, and transforming properties in human cells. Cancer Invest. 2010;28:563-87 pubmed 出版商
Hancock R, Hadj Sahraoui Y. Isolation of cell nuclei using inert macromolecules to mimic the crowded cytoplasm. PLoS ONE. 2009;4:e7560 pubmed 出版商
Zolotukhin A, Uranishi H, Lindtner S, Bear J, Pavlakis G, Felber B. Nuclear export factor RBM15 facilitates the access of DBP5 to mRNA. Nucleic Acids Res. 2009;37:7151-62 pubmed 出版商
Wang X, Belguise K, O Neill C, Sánchez Morgan N, Romagnoli M, Eddy S, et al. RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1. Mol Cell Biol. 2009;29:3832-44 pubmed 出版商
Garcia M, Byfield R, Robek M. Hepatitis B virus replication and release are independent of core lysine ubiquitination. J Virol. 2009;83:4923-33 pubmed 出版商
Tousseyn T, Thathiah A, Jorissen E, Raemaekers T, Konietzko U, Reiss K, et al. ADAM10, the rate-limiting protease of regulated intramembrane proteolysis of Notch and other proteins, is processed by ADAMS-9, ADAMS-15, and the gamma-secretase. J Biol Chem. 2009;284:11738-47 pubmed 出版商
Yan P, Fu J, Qu Z, Li S, Tanaka T, Grusby M, et al. PDLIM2 suppresses human T-cell leukemia virus type I Tax-mediated tumorigenesis by targeting Tax into the nuclear matrix for proteasomal degradation. Blood. 2009;113:4370-80 pubmed 出版商
Tapia R, Huerta M, Islas S, Avila Flores A, Lopez Bayghen E, Weiske J, et al. Zona occludens-2 inhibits cyclin D1 expression and cell proliferation and exhibits changes in localization along the cell cycle. Mol Biol Cell. 2009;20:1102-17 pubmed 出版商
MacPherson M, Beatty L, Zhou W, Du M, Sadowski P. The CTCF insulator protein is posttranslationally modified by SUMO. Mol Cell Biol. 2009;29:714-25 pubmed 出版商
Salsman J, Zimmerman N, Chen T, Domagala M, Frappier L. Genome-wide screen of three herpesviruses for protein subcellular localization and alteration of PML nuclear bodies. PLoS Pathog. 2008;4:e1000100 pubmed 出版商
Xu M, Cook P. Similar active genes cluster in specialized transcription factories. J Cell Biol. 2008;181:615-23 pubmed 出版商
Konietzko U, Goodger Z, Meyer M, Kohli B, Bosset J, Lahiri D, et al. Co-localization of the amyloid precursor protein and Notch intracellular domains in nuclear transcription factories. Neurobiol Aging. 2010;31:58-73 pubmed 出版商
Huerta M, Munoz R, Tapia R, Soto Reyes E, Ramírez L, Recillas Targa F, et al. Cyclin D1 is transcriptionally down-regulated by ZO-2 via an E box and the transcription factor c-Myc. Mol Biol Cell. 2007;18:4826-36 pubmed
Tanaka T, Grusby M, Kaisho T. PDLIM2-mediated termination of transcription factor NF-kappaB activation by intranuclear sequestration and degradation of the p65 subunit. Nat Immunol. 2007;8:584-91 pubmed
Kobayakawa S, Miike K, Nakao M, Abe K. Dynamic changes in the epigenomic state and nuclear organization of differentiating mouse embryonic stem cells. Genes Cells. 2007;12:447-60 pubmed
Hivin P, Basbous J, Raymond F, Henaff D, Arpin André C, Robert Hebmann V, et al. The HBZ-SP1 isoform of human T-cell leukemia virus type I represses JunB activity by sequestration into nuclear bodies. Retrovirology. 2007;4:14 pubmed
Brooks W, Banerjee S, Crawford D. G2E3 is a nucleo-cytoplasmic shuttling protein with DNA damage responsive localization. Exp Cell Res. 2007;313:665-76 pubmed
Psahoulia F, Moumtzi S, Roberts M, Sasazuki T, Shirasawa S, Pintzas A. Quercetin mediates preferential degradation of oncogenic Ras and causes autophagy in Ha-RAS-transformed human colon cells. Carcinogenesis. 2007;28:1021-31 pubmed
Markus M, Morris B. Lark is the splicing factor RBM4 and exhibits unique subnuclear localization properties. DNA Cell Biol. 2006;25:457-64 pubmed
Watzke A, Köhn M, Gutierrez Rodriguez M, Wacker R, Schröder H, Breinbauer R, et al. Site-selective protein immobilization by Staudinger ligation. Angew Chem Int Ed Engl. 2006;45:1408-12 pubmed
Barboric M, Kohoutek J, Price J, Blazek D, Price D, Peterlin B. Interplay between 7SK snRNA and oppositely charged regions in HEXIM1 direct the inhibition of P-TEFb. EMBO J. 2005;24:4291-303 pubmed
Boito R, Menniti M, Amato R, Palmieri C, Marinaro C, Iuliano R, et al. RFX-1, a putative alpha Adducin interacting protein in a human kidney library. FEBS Lett. 2005;579:6439-43 pubmed
Roberts M, Drosopoulos K, Vasileiou I, Stricker M, Taoufik E, Maercker C, et al. Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line. Int J Cancer. 2006;118:616-27 pubmed
Abu Baker A, Laganiere S, Fan X, Laganiere J, Brais B, Rouleau G. Cytoplasmic targeting of mutant poly(A)-binding protein nuclear 1 suppresses protein aggregation and toxicity in oculopharyngeal muscular dystrophy. Traffic. 2005;6:766-79 pubmed
Miele A, Braastad C, Holmes W, Mitra P, Medina R, Xie R, et al. HiNF-P directly links the cyclin E/CDK2/p220NPAT pathway to histone H4 gene regulation at the G1/S phase cell cycle transition. Mol Cell Biol. 2005;25:6140-53 pubmed
Vemuganti R, Dempsey R. Carotid atherosclerotic plaques from symptomatic stroke patients share the molecular fingerprints to develop in a neoplastic fashion: a microarray analysis study. Neuroscience. 2005;131:359-74 pubmed
Kamachi M, Le T, Kim S, Geiger M, Anderson P, Utz P. Human autoimmune sera as molecular probes for the identification of an autoantigen kinase signaling pathway. J Exp Med. 2002;196:1213-25 pubmed
产品信息
产品名称 :
H-Ras (259) Antibody
基因名称 :
HRAS, KRAS, NRAS
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-35
类型 :
单克隆
宿主 :
大鼠单克隆
抗原 :
H-Ras
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, FCM, 酶联免疫吸附测定
表位 :
FL(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。