产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
p53(DO-7)抗体
目录 :
sc-47698
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
DO-7
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 30
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 3d
Lee J, Park I, Kwak M, Rhee W, Kim S, Shin J. HMGB1 orchestrates STING-mediated senescence via TRIM30α modulation in cancer cells. Cell Death Discov. 2021;7:28 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6b
Blanden A, Yu X, Blayney A, Demas C, Ha J, Liu Y, et al. Zinc shapes the folding landscape of p53 and establishes a pathway for reactivating structurally diverse cancer mutants. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5b
Li K, Zhao S, Long J, Su J, Wu L, Tao J, et al. A novel chalcone derivative has antitumor activity in melanoma by inducing DNA damage through the upregulation of ROS products. Cancer Cell Int. 2020;20:36 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 3b
Ng S, Yoshida N, Christie A, Ghandi M, Dharia N, Dempster J, et al. Targetable vulnerabilities in T- and NK-cell lymphomas identified through preclinical models. Nat Commun. 2018;9:2024 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 5b
Solomon H, Dinowitz N, Pateras I, Cooks T, Shetzer Y, Molchadsky A, et al. Mutant p53 gain of function underlies high expression levels of colorectal cancer stem cells markers. Oncogene. 2018;37:1669-1684 pubmed 出版商
  • 免疫印迹; 人类; 图 2e
Zhao X, Huang L, Xu W, Chen X, Shen Y, Zeng W, et al. Physapubescin B inhibits tumorgenesis and circumvents taxol resistance of ovarian cancer cells through STAT3 signaling. Oncotarget. 2017;8:70130-70141 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3b
Lian W, Zhang L, Yang L, Chen W. AP-2α reverses vincristine-induced multidrug resistance of SGC7901 gastric cancer cells by inhibiting the Notch pathway. Apoptosis. 2017;22:933-941 pubmed 出版商
  • 免疫印迹; 人类; 1:400; 图 3a
Xu S, Yang Z, Fan Y, Guan B, Jia J, Gao Y, et al. Curcumin enhances temsirolimus-induced apoptosis in human renal carcinoma cells through upregulation of YAP/p53. Oncol Lett. 2016;12:4999-5006 pubmed 出版商
  • 免疫印迹; 人类; 图 5e
Pires A, Marques C, Encarnação J, Abrantes A, Mamede A, Laranjo M, et al. Ascorbic acid and colon cancer: an oxidative stimulus to cell death depending on cell profile. Eur J Cell Biol. 2016;95:208-18 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Brito A, Ribeiro M, Abrantes A, Mamede A, Laranjo M, Casalta Lopes J, et al. New Approach for Treatment of Primary Liver Tumors: The Role of Quercetin. Nutr Cancer. 2016;68:250-66 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Xie X, Lozano G, Siddik Z. Heterozygous p53(V172F) mutation in cisplatin-resistant human tumor cells promotes MDM4 recruitment and decreases stability and transactivity of p53. Oncogene. 2016;35:4798-806 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Ying M, Zhang L, Zhou Q, Shao X, Cao J, Zhang N, et al. The E3 ubiquitin protein ligase MDM2 dictates all-trans retinoic acid-induced osteoblastic differentiation of osteosarcoma cells by modulating the degradation of RARα. Oncogene. 2016;35:4358-67 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50
Chen S, Wang W, Wang L, Lin Q, Zhao G, Xu G, et al. Glioneuronal tumours with features of rosette-forming glioneuronal tumours of the fourth ventricle and dysembryoplastic neuroepithelial tumours: a report of three cases. Histopathology. 2016;68:378-87 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Magni M, Ruscica V, Buscemi G, Kim J, Nachimuthu B, Fontanella E, et al. Chk2 and REGγ-dependent DBC1 regulation in DNA damage induced apoptosis. Nucleic Acids Res. 2014;42:13150-60 pubmed 出版商
Oh L, Hainaut P, Blanchet S, Ariffin H. Expression of p53 N-terminal isoforms in B-cell precursor acute lymphoblastic leukemia and its correlation with clinicopathological profiles. BMC Cancer. 2020;20:110 pubmed 出版商
Cho H, Min H, Won Y, Ahn H, Cho Y, Seo K. Solid state fermentation process with Aspergillus kawachii enhances the cancer-suppressive potential of silkworm larva in hepatocellular carcinoma cells. BMC Complement Altern Med. 2019;19:241 pubmed 出版商
Wu Y, Li Y, Zhao X, Dong D, Tang C, Li E, et al. Combined detection of the expression of Nm23-H1 and p53 is correlated with survival rates of patients with stage II and III colorectal cancer. Oncol Lett. 2017;13:129-136 pubmed 出版商
Ohashi T, Komatsu S, Ichikawa D, Miyamae M, Okajima W, Imamura T, et al. Overexpression of PBK/TOPK relates to tumour malignant potential and poor outcome of gastric carcinoma. Br J Cancer. 2017;116:218-226 pubmed 出版商
Varela A, Piperi C, Sigala F, Agrogiannis G, Davos C, Andri M, et al. Elevated expression of mechanosensory polycystins in human carotid atherosclerotic plaques: association with p53 activation and disease severity. Sci Rep. 2015;5:13461 pubmed 出版商
Chen L, Rousseau R, Middleton S, Nichols G, Newell D, Lunec J, et al. Pre-clinical evaluation of the MDM2-p53 antagonist RG7388 alone and in combination with chemotherapy in neuroblastoma. Oncotarget. 2015;6:10207-21 pubmed
Pozzo F, Dal Bo M, Peragine N, Bomben R, Zucchetto A, Rossi F, et al. Detection of TP53 dysfunction in chronic lymphocytic leukemia by an in vitro functional assay based on TP53 activation by the non-genotoxic drug Nutlin-3: a proposal for clinical application. J Hematol Oncol. 2013;6:83 pubmed 出版商
Shilkaitis A, Bratescu L, Green A, Yamada T, Christov K. Bexarotene induces cellular senescence in MMTV-Neu mouse model of mammary carcinogenesis. Cancer Prev Res (Phila). 2013;6:299-308 pubmed 出版商
Ohshima S. Centrosome aberrations associated with cellular senescence and p53 localization at supernumerary centrosomes. Oxid Med Cell Longev. 2012;2012:217594 pubmed 出版商
Wu X, Zhu Z, Li W, Fu X, Su D, Fu L, et al. Chromodomain helicase DNA binding protein 5 plays a tumor suppressor role in human breast cancer. Breast Cancer Res. 2012;14:R73 pubmed
Chen Y, Shen D, Gu Y, Zhong P, Xie J, Song Q. The diagnostic value of Ki-67, P53 and P63 in distinguishing partial Hydatidiform mole from hydropic abortion. Wien Klin Wochenschr. 2012;124:184-7 pubmed 出版商
Shirakawa M, Fujiwara Y, Sugita Y, Moon J, Takiguchi S, Nakajima K, et al. Assessment of stanniocalcin-1 as a prognostic marker in human esophageal squamous cell carcinoma. Oncol Rep. 2012;27:940-6 pubmed 出版商
Tagoug I, Sauty De Chalon A, Dumontet C. Inhibition of IGF-1 signalling enhances the apoptotic effect of AS602868, an IKK2 inhibitor, in multiple myeloma cell lines. PLoS ONE. 2011;6:e22641 pubmed 出版商
Jing M, Mao X, Li C, Wei J, Liu C, Jin F. Estrogen receptor-alpha promoter methylation in sporadic basal-like breast cancer of Chinese women. Tumour Biol. 2011;32:713-9 pubmed 出版商
Mao X, Fan C, Zheng H, Wei J, Yao F, Jin F. p53 nuclear accumulation and ERalpha expression in ductal hyperplasia of breast in a cohort of 215 Chinese women. J Exp Clin Cancer Res. 2010;29:112 pubmed 出版商
Morselli E, Tasdemir E, Maiuri M, Galluzzi L, Kepp O, Criollo A, et al. Mutant p53 protein localized in the cytoplasm inhibits autophagy. Cell Cycle. 2008;7:3056-61 pubmed
产品信息
产品名称 :
p53(DO-7)抗体
基因名称 :
TP53
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-47698
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
p53
反应物种 :
人类
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), FCM
表位 :
1-45(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。