产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
Pol II (CTD4H8) Antibody
目录 :
sc-47701
规格 :
200微克/毫升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
CTD4H8
反应物种 :
人类, 小鼠, 大鼠, 拟南芥
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 35
出版应用/物种/样本/稀释参考文献
  • 染色质免疫沉淀 ; 小鼠; 1:10; 图 2e
Reddy N, Majidi S, Kong L, Nemera M, Ferguson C, Moore M, et al. CHARGE syndrome protein CHD7 regulates epigenomic activation of enhancers in granule cell precursors and gyrification of the cerebellum. Nat Commun. 2021;12:5702 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 2d, e2i
Wu S, Fukumoto T, Lin J, Nacarelli T, Wang Y, Ong D, et al. Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma. Nat Cancer. 2021;2:189-200 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:200; 图 s6d
  • 免疫细胞化学; 人类; 1:200; 图 s4f
  • 免疫印迹; 人类; 1:5000; 图 7a
Li Y, Liu Y, Xu H, Jiang G, Van der Jeught K, Fang Y, et al. Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II. Nat Commun. 2018;9:4394 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Bujko M, Kober P, Statkiewicz M, Mikula M, Ligaj M, Zwierzchowski L, et al. Epigenetic-Mediated Downregulation of μ-Protocadherin in Colorectal Tumours. Gastroenterol Res Pract. 2015;2015:317093 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 s1
  • 免疫印迹; 人类; 图 s3d
Liu Y, Zhang X, Han C, Wan G, Huang X, Ivan C, et al. TP53 loss creates therapeutic vulnerability in colorectal cancer. Nature. 2015;520:697-701 pubmed 出版商
  • 染色质免疫沉淀 ; 拟南芥; 图 4
Dolata J, Guo Y, KoÅ‚owerzo A, SmoliÅ„ski D, Brzyżek G, JarmoÅ‚owski A, et al. NTR1 is required for transcription elongation checkpoints at alternative exons in Arabidopsis. EMBO J. 2015;34:544-58 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Ji X, Lu H, Zhou Q, Luo K. LARP7 suppresses P-TEFb activity to inhibit breast cancer progression and metastasis. elife. 2014;3:e02907 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Attucks O, Jasmer K, Hannink M, Kassis J, Zhong Z, Gupta S, et al. Induction of heme oxygenase I (HMOX1) by HPP-4382: a novel modulator of Bach1 activity. PLoS ONE. 2014;9:e101044 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 4d
Veronese A, Pepe F, Chiacchia J, Pagotto S, Lanuti P, Veschi S, et al. Allele-specific loss and transcription of the miR-15a/16-1 cluster in chronic lymphocytic leukemia. Leukemia. 2015;29:86-95 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 免疫细胞化学; 人类
Madak Erdogan Z, Ventrella R, Petry L, Katzenellenbogen B. Novel roles for ERK5 and cofilin as critical mediators linking ER?-driven transcription, actin reorganization, and invasiveness in breast cancer. Mol Cancer Res. 2014;12:714-27 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 染色质免疫沉淀 ; 小鼠
Fowler T, Ghatak P, Price D, Conaway R, Conaway J, Chiang C, et al. Regulation of MYC expression and differential JQ1 sensitivity in cancer cells. PLoS ONE. 2014;9:e87003 pubmed 出版商
Mersaoui S, Yu Z, Coulombe Y, Karam M, Busatto F, Masson J, et al. Arginine methylation of the DDX5 helicase RGG/RG motif by PRMT5 regulates resolution of RNA:DNA hybrids. EMBO J. 2019;38:e100986 pubmed 出版商
Wu S, Fatkhutdinov N, Rosin L, Luppino J, Iwasaki O, Tanizawa H, et al. ARID1A spatially partitions interphase chromosomes. Sci Adv. 2019;5:eaaw5294 pubmed 出版商
Petrie J, Swan C, Ingram R, Frame F, Collins A, Dumay Odelot H, et al. Effects on prostate cancer cells of targeting RNA polymerase III. Nucleic Acids Res. 2019;47:3937-3956 pubmed 出版商
Wu S, Fatkhutdinov N, Fukumoto T, Bitler B, Park P, Kossenkov A, et al. SWI/SNF catalytic subunits' switch drives resistance to EZH2 inhibitors in ARID1A-mutated cells. Nat Commun. 2018;9:4116 pubmed 出版商
Haynes P, Bomsztyk K, Miller D. Sporadic DUX4 expression in FSHD myocytes is associated with incomplete repression by the PRC2 complex and gain of H3K9 acetylation on the contracted D4Z4 allele. Epigenetics Chromatin. 2018;11:47 pubmed 出版商
Sun C, Yin J, Fang Y, Chen J, Jeong K, Chen X, et al. BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency. Cancer Cell. 2018;33:401-416.e8 pubmed 出版商
Koch M, House N, Cosetta C, Jong R, Salomon C, Joyce C, et al. The Chromatin Remodeler Isw1 Prevents CAG Repeat Expansions During Transcription in Saccharomyces cerevisiae. Genetics. 2018;208:963-976 pubmed 出版商
Parvathaneni S, Lu X, Chaudhary R, Lal A, Madhusudan S, Sharma S. RECQ1 expression is upregulated in response to DNA damage and in a p53-dependent manner. Oncotarget. 2017;8:75924-75942 pubmed 出版商
Mikula M, Bomsztyk K, Goryca K, Chojnowski K, Ostrowski J. Heterogeneous nuclear ribonucleoprotein (HnRNP) K genome-wide binding survey reveals its role in regulating 3'-end RNA processing and transcription termination at the early growth response 1 (EGR1) gene through XRN2 exonuclease. J Biol Chem. 2013;288:24788-98 pubmed 出版商
Yamada K, Hayashi M, Madokoro H, Nishida H, Du W, Ohnuma K, et al. Nuclear localization of CD26 induced by a humanized monoclonal antibody inhibits tumor cell growth by modulating of POLR2A transcription. PLoS ONE. 2013;8:e62304 pubmed 出版商
Zhang Z, Liu R, Townsend P, Proud C. p90(RSK)s mediate the activation of ribosomal RNA synthesis by the hypertrophic agonist phenylephrine in adult cardiomyocytes. J Mol Cell Cardiol. 2013;59:139-47 pubmed 出版商
Komers R, Mar D, Denisenko O, Xu B, Oyama T, Bomsztyk K. Epigenetic changes in renal genes dysregulated in mouse and rat models of type 1 diabetes. Lab Invest. 2013;93:543-52 pubmed 出版商
van Rensburg R, Beyer I, Yao X, Wang H, Denisenko O, Li Z, et al. Chromatin structure of two genomic sites for targeted transgene integration in induced pluripotent stem cells and hematopoietic stem cells. Gene Ther. 2013;20:201-14 pubmed 出版商
Yu J, Feng Q, Ruan Y, Komers R, Kiviat N, Bomsztyk K. Microplate-based platform for combined chromatin and DNA methylation immunoprecipitation assays. BMC Mol Biol. 2011;12:49 pubmed 出版商
Melvin A, Mudie S, Rocha S. The chromatin remodeler ISWI regulates the cellular response to hypoxia: role of FIH. Mol Biol Cell. 2011;22:4171-81 pubmed 出版商
Culver C, Melvin A, Mudie S, Rocha S. HIF-1α depletion results in SP1-mediated cell cycle disruption and alters the cellular response to chemotherapeutic drugs. Cell Cycle. 2011;10:1249-60 pubmed
van Uden P, Kenneth N, Webster R, Müller H, Mudie S, Rocha S. Evolutionary conserved regulation of HIF-1β by NF-κB. PLoS Genet. 2011;7:e1001285 pubmed 出版商
Brody Y, Neufeld N, Bieberstein N, Causse S, Böhnlein E, Neugebauer K, et al. The in vivo kinetics of RNA polymerase II elongation during co-transcriptional splicing. PLoS Biol. 2011;9:e1000573 pubmed 出版商
Nelson J, Denisenko O, Bomsztyk K. Profiling RNA polymerase II using the fast chromatin immunoprecipitation method. Methods Mol Biol. 2011;703:219-34 pubmed 出版商
Newton I, Kenneth N, Appleton P, Näthke I, Rocha S. Adenomatous polyposis coli and hypoxia-inducible factor-1{alpha} have an antagonistic connection. Mol Biol Cell. 2010;21:3630-8 pubmed 出版商
Mikula M, Gaj P, Dzwonek K, Rubel T, Karczmarski J, Paziewska A, et al. Comprehensive analysis of the palindromic motif TCTCGCGAGA: a regulatory element of the HNRNPK promoter. DNA Res. 2010;17:245-60 pubmed 出版商
Mikula M, Hanusek K, Paziewska A, Dzwonek A, Rubel T, Bomsztyk K, et al. Halogenated imidazole derivatives block RNA polymerase II elongation along mitogen inducible genes. BMC Mol Biol. 2010;11:4 pubmed 出版商
Birch J, Tan B, Panov K, Panova T, Andersen J, Owen Hughes T, et al. FACT facilitates chromatin transcription by RNA polymerases I and III. EMBO J. 2009;28:854-65 pubmed 出版商
Kenneth N, Mudie S, van Uden P, Rocha S. SWI/SNF regulates the cellular response to hypoxia. J Biol Chem. 2009;284:4123-31 pubmed 出版商
产品信息
产品名称 :
Pol II (CTD4H8) Antibody
基因名称 :
POLR2A
规格 :
200微克/毫升
目录号 :
sc-47701
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
Pol II
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P)
表位 :
Ser-5 (h)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。