产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
Akt1(B-1)抗体
目录 :
sc-5298
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
B-1
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 98
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 5c
Wu Y, Chou T, Young L, Hsieh F, Pan H, Mo S, et al. Tumor suppressor death-associated protein kinase 1 inhibits necroptosis by p38 MAPK activation. Cell Death Dis. 2020;11:305 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Lai S, Lin H, Liu Y, Yang L, Lu D. Monocarboxylate Transporter 4 Regulates Glioblastoma Motility and Monocyte Binding Ability. Cancers (Basel). 2020;12: pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Barbero G, Castro M, Villanueva M, Quezada M, Fernández N, Demorrow S, et al. An Autocrine Wnt5a Loop Promotes NF-κB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma. Cells. 2019;8: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3a
El Kott A, Shati A, Al Kahtani M, Alqahtani S. Acylated Ghrelin Renders Chemosensitive Ovarian Cancer Cells Resistant to Cisplatin Chemotherapy via Activation of the PI3K/Akt/mTOR Survival Pathway. Anal Cell Pathol (Amst). 2019;2019:9627810 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3c
Li J, Liu X, Chen H, Sun Z, Chen H, Wang L, et al. Multi-targeting chemoprevention of Chinese herb formula Yanghe Huayan decoction on experimentally induced mammary tumorigenesis. BMC Complement Altern Med. 2019;19:48 pubmed 出版商
  • 免疫沉淀; 人类; 图 5i
  • 免疫印迹; 人类; 图 5i
  • 免疫印迹; 小鼠; 图 5k, 5m
Li W, Yue F, Dai Y, Shi B, Xu G, Jiang X, et al. Suppressor of hepatocellular carcinoma RASSF1A activates autophagy initiation and maturation. Cell Death Differ. 2018;: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Zhu L, Xie X, Zhang L, Wang H, Jie Z, Zhou X, et al. TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival. Nat Commun. 2018;9:2812 pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Miyamoto T, Lo P, Saichi N, Ueda K, Hirata M, Tanikawa C, et al. Argininosuccinate synthase 1 is an intrinsic Akt repressor transactivated by p53. Sci Adv. 2017;3:e1603204 pubmed 出版商
  • 免疫印迹; 人类; 图 s6o
Ooi J, Petersen J, Tan Y, Huynh M, Willett Z, Ramarathinam S, et al. Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells. Nature. 2017;545:243-247 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3a
Ting W, Huang C, Jiang C, Lin Y, Chung L, Shen C, et al. Treatment with 17?-Estradiol Reduced Body Weight and the Risk of Cardiovascular Disease in a High-Fat Diet-Induced Animal Model of Obesity. Int J Mol Sci. 2017;18: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4d
Li S, Sun S, Gao J, Sun F. Wogonin induces Beclin-1/PI3K and reactive oxygen species-mediated autophagy in human pancreatic cancer cells. Oncol Lett. 2016;12:5059-5067 pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 6a
Liu W, Huang K, Lu M, Huang H, Chen C, Cheng Y, et al. TGF-β upregulates the translation of USP15 via the PI3K/AKT pathway to promote p53 stability. Oncogene. 2017;36:2715-2723 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 5a
Zhong W, Wang X, Pan B, Li F, Kuang L, Su Z. Eupatilin induces human renal cancer cell apoptosis via ROS-mediated MAPK and PI3K/AKT signaling pathways. Oncol Lett. 2016;12:2894-2899 pubmed
  • 免疫印迹; 人类; 图 5a
Tai Y, Tung L, Lin Y, Lu P, Chu P, Wang M, et al. Grb7 Protein Stability Modulated by Pin1 in Association with Cell Cycle Progression. PLoS ONE. 2016;11:e0163617 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 4
Suman S, Kumar S, Fornace A, Datta K. Space radiation exposure persistently increased leptin and IGF1 in serum and activated leptin-IGF1 signaling axis in mouse intestine. Sci Rep. 2016;6:31853 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Subramanian P, An Z, Yu J, Park W. Silencing of fused toes homolog enhances cisplatin sensitivity in cervical cancer cells by inhibiting epidermal growth factor receptor-mediated repair of DNA damage. Cancer Chemother Pharmacol. 2016;78:753-62 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 5b
Liu S, Zhou F, Shen Y, Zhang Y, Yin H, Zeng Y, et al. Fluid shear stress induces epithelial-mesenchymal transition (EMT) in Hep-2 cells. Oncotarget. 2016;7:32876-92 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 3
Maselli A, Capoccia S, Pugliese P, Raggi C, Cirulli F, Fabi A, et al. Autoantibodies specific to estrogen receptor alpha act as estrogen agonists and their levels correlate with breast cancer cell proliferation. Oncoimmunology. 2016;5:e1074375 pubmed
  • 免疫印迹; 小鼠; 图 5
  • 免疫印迹; 人类; 图 8
Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed 出版商
  • 免疫印迹; 人类; 图 S3
Wang Z, Ma B, Li H, Xiao X, Zhou W, Liu F, et al. Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC. Oncotarget. 2016;7:509-23 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Amigo Jiménez I, Bailón E, Aguilera Montilla N, Terol M, García Marco J, García Pardo A. Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways. Oncotarget. 2015;6:44832-48 pubmed 出版商
  • 免疫印迹; 大鼠
Rizvi F, Mathur A, Krishna S, Siddiqi M, Kakkar P. Suppression in PHLPP2 induction by morin promotes Nrf2-regulated cellular defenses against oxidative injury to primary rat hepatocytes. Redox Biol. 2015;6:587-598 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8
Miyamoto Y, Torii T, Takada S, Ohno N, Saitoh Y, Nakamura K, et al. Involvement of the Tyro3 receptor and its intracellular partner Fyn signaling in Schwann cell myelination. Mol Biol Cell. 2015;26:3489-503 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 4c
Santos J, Mesquita D, Barros Silva J, Jerónimo C, Henrique R, Morais A, et al. Uncovering potential downstream targets of oncogenic GRPR overexpression in prostate carcinomas harboring ETS rearrangements. Oncoscience. 2015;2:497-507 pubmed
  • 免疫印迹; 大鼠; 图 5
Li P, Sheu M, Ma W, Pan C, Sheu J, Wu C. Anti-Restenotic Roles of Dihydroaustrasulfone Alcohol Involved in Inhibiting PDGF-BB-Stimulated Proliferation and Migration of Vascular Smooth Muscle Cells. Mar Drugs. 2015;13:3046-60 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500
Salvatierra C, Reis S, Pessoa A, De Souza L, Stoppiglia L, Veloso R, et al. Short-term low-protein diet during pregnancy alters islet area and protein content of phosphatidylinositol 3-kinase pathway in rats. An Acad Bras Cienc. 2015;87:1007-18 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Marathe S, Liu S, Brai E, Kaczarowski M, Alberi L. Notch signaling in response to excitotoxicity induces neurodegeneration via erroneous cell cycle reentry. Cell Death Differ. 2015;22:1775-84 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Tassinari V, Campolo F, Cesarini V, Todaro F, Dolci S, Rossi P. Fgf9 inhibition of meiotic differentiation in spermatogonia is mediated by Erk-dependent activation of Nodal-Smad2/3 signaling and is antagonized by Kit Ligand. Cell Death Dis. 2015;6:e1688 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 4
Suman S, Kallakury B, Fornace A, Datta K. Protracted upregulation of leptin and IGF1 is associated with activation of PI3K/Akt and JAK2 pathway in mouse intestine after ionizing radiation exposure. Int J Biol Sci. 2015;11:274-83 pubmed 出版商
  • 免疫印迹; 人类
Shen Y, Gao M, Ma Y, Yu H, Cui F, Gregersen H, et al. Effect of surface chemistry on the integrin induced pathway in regulating vascular endothelial cells migration. Colloids Surf B Biointerfaces. 2015;126:188-97 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Chen Y, Wei M, Wang C, Lee H, Pan S, Gao M, et al. Dual phosphoinositide 3-kinase/mammalian target of rapamycin inhibitor is an effective radiosensitizer for colorectal cancer. Cancer Lett. 2015;357:582-90 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Chavali P, Saini R, Zhai Q, Vizlin Hodzic D, Venkatabalasubramanian S, Hayashi A, et al. TLX activates MMP-2, promotes self-renewal of tumor spheres in neuroblastoma and correlates with poor patient survival. Cell Death Dis. 2014;5:e1502 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
  • 免疫印迹; 人类; 图 1
Badolia R, Manne B, Dangelmaier C, Chernoff J, Kunapuli S. Gq-mediated Akt translocation to the membrane: a novel PIP3-independent mechanism in platelets. Blood. 2015;125:175-84 pubmed 出版商
  • 免疫印迹; 人类
Bailon E, Ugarte Berzal E, Amigo Jiménez I, Van den Steen P, Opdenakker G, Garcia Marco J, et al. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen. J Leukoc Biol. 2014;96:185-99 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类
Choi Y, Kim Y, Jeong H, Jin Y, Yeo C, Lee K. Akt enhances Runx2 protein stability by regulating Smurf2 function during osteoblast differentiation. FEBS J. 2014;281:3656-66 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Tanaka T, Iino M. Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1. Cell Signal. 2014;26:2071-85 pubmed 出版商
  • 免疫印迹; 人类
Subramani R, Lopez Valdez R, Arumugam A, Nandy S, Boopalan T, Lakshmanaswamy R. Targeting insulin-like growth factor 1 receptor inhibits pancreatic cancer growth and metastasis. PLoS ONE. 2014;9:e97016 pubmed 出版商
  • 免疫印迹; 人类
Liu X, Chen L, Feng B, Liu G. Reversing effect of sorcin in the drug resistance of human nasopharyngeal carcinoma. Anat Rec (Hoboken). 2014;297:215-21 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Tanaka T, Iino M. Knockdown of Sec8 promotes cell-cycle arrest at G1/S phase by inducing p21 via control of FOXO proteins. FEBS J. 2014;281:1068-84 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5
Qi L, Zhang Y. Truncation of inhibitor of growth family protein 5 effectively induces senescence, but not apoptosis in human tongue squamous cell carcinoma cell line. Tumour Biol. 2014;35:3139-44 pubmed 出版商
Glorieux C, Xia X, He Y, Hu Y, Cremer K, Robert A, et al. Regulation of PD-L1 expression in K-ras-driven cancers through ROS-mediated FGFR1 signaling. Redox Biol. 2021;38:101780 pubmed 出版商
Chen K, Jiao X, Di Rocco A, Shen D, Xu S, Ertel A, et al. Endogenous Cyclin D1 Promotes the Rate of Onset and Magnitude of Mitogenic Signaling via Akt1 Ser473 Phosphorylation. Cell Rep. 2020;32:108151 pubmed 出版商
Al Khayal K, Vaali Mohammed M, Elwatidy M, Bin Traiki T, Al Obeed O, Azam M, et al. A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway. BMC Cancer. 2020;20:685 pubmed 出版商
Huang Y, Lin C, Tsai H, Fong Y, Han C, Huang Y, et al. Amphiregulin promotes cisplatin chemoresistance by upregulating ABCB1 expression in human chondrosarcoma. Aging (Albany NY). 2020;12:9475-9488 pubmed 出版商
Clapper E, Wang S, Raninga P, Di Trapani G, Tonissen K. Cross-talk between Bcr-abl and the Thioredoxin System in Chronic Myeloid Leukaemia: Implications for CML Treatment. Antioxidants (Basel). 2020;9: pubmed 出版商
Molagoda I, Lee K, Choi Y, Kim G. Anthocyanins from Hibiscus syriacus L. Inhibit Oxidative Stress-Mediated Apoptosis by Activating the Nrf2/HO-1 Signaling Pathway. Antioxidants (Basel). 2020;9: pubmed 出版商
López Grueso M, Gonzalez R, Muntane J, Bárcena J, Padilla C. Thioredoxin Downregulation Enhances Sorafenib Effects in Hepatocarcinoma Cells. Antioxidants (Basel). 2019;8: pubmed 出版商
Zhan Y, Wang Y, Qi M, Liang P, Ma Y, Li T, et al. BH3 mimetic ABT-263 enhances the anticancer effects of apigenin in tumor cells with activating EGFR mutation. Cell Biosci. 2019;9:60 pubmed 出版商
Guo J, Dai X, Laurent B, Zheng N, Gan W, Zhang J, et al. AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions. Nat Cell Biol. 2019;21:226-237 pubmed 出版商
Chai C, Wu H, Wang B, Eisenstat D, Leng R. MicroRNA-498 promotes proliferation and migration by targeting the tumor suppressor PTEN in breast cancer cells. Carcinogenesis. 2018;39:1185-1196 pubmed 出版商
Agod Z, Pazmandi K, Bencze D, Vereb G, Biro T, Szabo A, et al. Signaling Lymphocyte Activation Molecule Family 5 Enhances Autophagy and Fine-Tunes Cytokine Response in Monocyte-Derived Dendritic Cells via Stabilization of Interferon Regulatory Factor 8. Front Immunol. 2018;9:62 pubmed 出版商
Zhou X, Dong S, Liu Z, Liu S, Zhang C, Liang X. Regulation of gammaherpesvirus lytic replication by endoplasmic reticulum stress-induced transcription factors ATF4 and CHOP. J Biol Chem. 2018;293:2801-2814 pubmed 出版商
Srivastava S, Mohibi S, Mirza S, Band H, Band V. Epidermal Growth Factor Receptor activation promotes ADA3 acetylation through the AKT-p300 pathway. Cell Cycle. 2017;16:1515-1525 pubmed 出版商
Badolia R, Inamdar V, Manne B, Dangelmaier C, Eble J, Kunapuli S. Gq pathway regulates proximal C-type lectin-like receptor-2 (CLEC-2) signaling in platelets. J Biol Chem. 2017;292:14516-14531 pubmed 出版商
Li W, Chen L, Chen Z, Wu L, Feng J, Wang F, et al. Dentin sialoprotein facilitates dental mesenchymal cell differentiation and dentin formation. Sci Rep. 2017;7:300 pubmed 出版商
Toledano S, Lu H, Palacio A, Ziv K, Kessler O, Schaal S, et al. A Sema3C Mutant Resistant to Cleavage by Furin (FR-Sema3C) Inhibits Choroidal Neovascularization. PLoS ONE. 2016;11:e0168122 pubmed 出版商
Liao P, Kuo W, Hsieh D, Yeh Y, Day C, Chen Y, et al. Heat-killed Lactobacillus Reuteri GMNL-263 Prevents Epididymal Fat Accumulation and Cardiac Injury in High-Calorie Diet-Fed Rats. Int J Med Sci. 2016;13:569-77 pubmed 出版商
Zhang H, Li H. miR-137 inhibits renal cell carcinoma growth in vitro and in vivo. Oncol Lett. 2016;12:715-720 pubmed
Kang H, Ahn D, Pak J, Seo K, Baek N, Jang S. Magnobovatol inhibits smooth muscle cell migration by suppressing PDGF-R? phosphorylation and inhibiting matrix metalloproteinase-2 expression. Int J Mol Med. 2016;37:1239-46 pubmed 出版商
Xu T, Wu S, Yuan Y, Yan G, Xiao D. Knockdown of phosphodiesterase 4D inhibits nasopharyngeal carcinoma proliferation via the epidermal growth factor receptor signaling pathway. Oncol Lett. 2014;8:2110-2116 pubmed
Lu W, Kao S, Yang C, Tu H, Wu C, Chang K, et al. EGF up-regulates miR-31 through the C/EBPβ signal cascade in oral carcinoma. PLoS ONE. 2014;9:e108049 pubmed 出版商
Tin A, Park A, Sundar S, Firestone G. Essential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells. BMC Biol. 2014;12:72 pubmed 出版商
Liu N, Xi Y, Callaghan M, Fribley A, Moore Smith L, Zimmerman J, et al. SMAD4 is a potential prognostic marker in human breast carcinomas. Tumour Biol. 2014;35:641-50 pubmed 出版商
Fekete A, Bogel G, Pesti S, Péterfi Z, Geiszt M, Buday L. EGF regulates tyrosine phosphorylation and membrane-translocation of the scaffold protein Tks5. J Mol Signal. 2013;8:8 pubmed 出版商
Bogazzi F, Raggi F, Russo D, Bohlooly Y M, Sardella C, Urbani C, et al. Growth hormone is necessary for the p53-mediated, obesity-induced insulin resistance in male C57BL/6J x CBA mice. Endocrinology. 2013;154:4226-36 pubmed 出版商
Yang Y, Li X, Wang L, Han S, Zhang Y, Pratheeshkumar P, et al. Anti-apoptotic proteins and catalase-dependent apoptosis resistance in nickel chloride-transformed human lung epithelial cells. Int J Oncol. 2013;43:936-46 pubmed 出版商
Son Y, Pratheeshkumar P, Wang L, Wang X, Fan J, Kim D, et al. Reactive oxygen species mediate Cr(VI)-induced carcinogenesis through PI3K/AKT-dependent activation of GSK-3?/?-catenin signaling. Toxicol Appl Pharmacol. 2013;271:239-48 pubmed 出版商
Murugan A, Alzahrani A, Xing M. Mutations in critical domains confer the human mTOR gene strong tumorigenicity. J Biol Chem. 2013;288:6511-21 pubmed 出版商
Cai N, Wang Y, Zheng P. The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1. RNA. 2013;19:85-95 pubmed 出版商
Blich M, Golan A, Arvatz G, Sebbag A, Shafat I, Sabo E, et al. Macrophage activation by heparanase is mediated by TLR-2 and TLR-4 and associates with plaque progression. Arterioscler Thromb Vasc Biol. 2013;33:e56-65 pubmed 出版商
Booher K, Lin D, Borrego S, Kaiser P. Downregulation of Cdc6 and pre-replication complexes in response to methionine stress in breast cancer cells. Cell Cycle. 2012;11:4414-23 pubmed 出版商
Son Y, Wang L, Poyil P, Budhraja A, Hitron J, Zhang Z, et al. Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3?/?-catenin signaling. Toxicol Appl Pharmacol. 2012;264:153-60 pubmed 出版商
Song S, Lee M, Lee J, Jeong H, Kim H, Kim W, et al. Genetic modification of human adipose-derived stem cells for promoting wound healing. J Dermatol Sci. 2012;66:98-107 pubmed 出版商
Hung S, Chiang H, Wu C, Hsu M, Chen Y. Effects of herpes simplex virus type 1 infection on immune functions of human neutrophils. J Periodontal Res. 2012;47:635-44 pubmed 出版商
Ali I, Damdimopoulou P, Stenius U, Adamsson A, Mäkelä S, Akesson A, et al. Cadmium-induced effects on cellular signaling pathways in the liver of transgenic estrogen reporter mice. Toxicol Sci. 2012;127:66-75 pubmed 出版商
Cohen Kaplan V, Jrbashyan J, Yanir Y, Naroditsky I, Ben Izhak O, Ilan N, et al. Heparanase induces signal transducer and activator of transcription (STAT) protein phosphorylation: preclinical and clinical significance in head and neck cancer. J Biol Chem. 2012;287:6668-78 pubmed 出版商
Nagel J, Brinkoetter M, Magkos F, Liu X, Chamberland J, Shah S, et al. Dietary walnuts inhibit colorectal cancer growth in mice by suppressing angiogenesis. Nutrition. 2012;28:67-75 pubmed 出版商
He K, Jang S, Joshi J, Yoo M, Ye K. Akt-phosphorylated PIKE-A inhibits UNC5B-induced apoptosis in cancer cell lines in a p53-dependent manner. Mol Biol Cell. 2011;22:1943-54 pubmed 出版商
Lin W, Rahman N, Lin J, Zhang H, Gou K, Yu W, et al. Molecular mechanisms of bladder outlet obstruction in transgenic male mice overexpressing aromatase (Cyp19a1). Am J Pathol. 2011;178:1233-44 pubmed 出版商
Zhang L, Sun S, Zhou J, Liu J, Lv J, Yu X, et al. Knockdown of Akt1 promotes Akt2 upregulation and resistance to oxidative-stress-induced apoptosis through control of multiple signaling pathways. Antioxid Redox Signal. 2011;15:1-17 pubmed 出版商
Mukherjee A, Badal Y, Nguyen X, Miller J, Chenna A, Tahir H, et al. Profiling the HER3/PI3K pathway in breast tumors using proximity-directed assays identifies correlations between protein complexes and phosphoproteins. PLoS ONE. 2011;6:e16443 pubmed 出版商
Leksa V, Loewe R, Binder B, Schiller H, Eckerstorfer P, Forster F, et al. Soluble M6P/IGF2R released by TACE controls angiogenesis via blocking plasminogen activation. Circ Res. 2011;108:676-85 pubmed 出版商
Motegi H, Shimo Y, Akiyama T, Inoue J. TRAF6 negatively regulates the Jak1-Erk pathway in interleukin-2 signaling. Genes Cells. 2011;16:179-89 pubmed 出版商
Zhang W, Lee J, Kim I, Kim Y, Park J, Myung C. 7-O-methylaromadendrin stimulates glucose uptake and improves insulin resistance in vitro. Biol Pharm Bull. 2010;33:1494-9 pubmed
Voutsadakis I, Patrikidou A, Tsapakidis K, Karagiannaki A, Hatzidaki E, Stathakis N, et al. Additive inhibition of colorectal cancer cell lines by aspirin and bortezomib. Int J Colorectal Dis. 2010;25:795-804 pubmed 出版商
Kalous J, Kubelka M, Solc P, Susor A, Motlik J. AKT (protein kinase B) is implicated in meiotic maturation of porcine oocytes. Reproduction. 2009;138:645-54 pubmed 出版商
Yellaturu C, Deng X, Cagen L, Wilcox H, Mansbach C, Siddiqi S, et al. Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles. J Biol Chem. 2009;284:7518-32 pubmed 出版商
Sundstrom J, Sundstrom C, Sundstrom S, Fort P, Rauscher R, Gardner T, et al. Phosphorylation site mapping of endogenous proteins: a combined MS and bioinformatics approach. J Proteome Res. 2009;8:798-807 pubmed 出版商
Chu C, Tzang B, Chen L, Liu C, Tsai F, Tsai C, et al. Activation of insulin-like growth factor II receptor induces mitochondrial-dependent apoptosis through G(alpha)q and downstream calcineurin signaling in myocardial cells. Endocrinology. 2009;150:2723-31 pubmed 出版商
Cohen Kaplan V, Doweck I, Naroditsky I, Vlodavsky I, Ilan N. Heparanase augments epidermal growth factor receptor phosphorylation: correlation with head and neck tumor progression. Cancer Res. 2008;68:10077-85 pubmed 出版商
Hayata K, Sakano K, Nishinaka S. Establishment of new highly insulin-sensitive cell lines and screening of compounds to facilitate glucose consumption. J Pharmacol Sci. 2008;108:348-54 pubmed
Palozza P, Sestito R, Picci N, Lanza P, Monego G, Ranelletti F. The sensitivity to beta-carotene growth-inhibitory and proapoptotic effects is regulated by caveolin-1 expression in human colon and prostate cancer cells. Carcinogenesis. 2008;29:2153-61 pubmed 出版商
Guo W, Zeng M, Yadav A, Song L, Guo B, Band V, et al. Mel-18 acts as a tumor suppressor by repressing Bmi-1 expression and down-regulating Akt activity in breast cancer cells. Cancer Res. 2007;67:5083-9 pubmed
Eidenschenk C, Jouanguy E, Alcais A, Mention J, Pasquier B, Fleckenstein I, et al. Familial NK cell deficiency associated with impaired IL-2- and IL-15-dependent survival of lymphocytes. J Immunol. 2006;177:8835-43 pubmed
Malmlöf M, Roudier E, Hogberg J, Stenius U. MEK-ERK-mediated phosphorylation of Mdm2 at Ser-166 in hepatocytes. Mdm2 is activated in response to inhibited Akt signaling. J Biol Chem. 2007;282:2288-96 pubmed
Redondo Muñoz J, Escobar Díaz E, Samaniego R, Terol M, Garcia Marco J, Garcia Pardo A. MMP-9 in B-cell chronic lymphocytic leukemia is up-regulated by alpha4beta1 integrin or CXCR4 engagement via distinct signaling pathways, localizes to podosomes, and is involved in cell invasion and migration. Blood. 2006;108:3143-51 pubmed
Kim C, Vasko V, Kato Y, Kruhlak M, Saji M, Cheng S, et al. AKT activation promotes metastasis in a mouse model of follicular thyroid carcinoma. Endocrinology. 2005;146:4456-63 pubmed
Kalous J, Solc P, Baran V, Kubelka M, Schultz R, Motlik J. PKB/AKT is involved in resumption of meiosis in mouse oocytes. Biol Cell. 2006;98:111-23 pubmed
产品信息
产品名称 :
Akt1(B-1)抗体
基因名称 :
AKT1
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-5298
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
Akt1
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), FCM, 酶联免疫吸附测定
表位 :
345-480(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。