产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
增殖细胞核抗原(PC10)抗体
目录 :
sc-56
规格 :
200微克/毫升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
PC10
反应物种 :
South American coati, African green monkey, tiger salamander, 日本大米鱼, 大西洋鳉, axolotl, 人类, 小鼠, 大鼠, , pigs
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, proximity ligation assay, dot blot, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 499
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 6b
Sun H, Ni H, McCracken J, Akakpo J, Fulte S, McKeen T, et al. Liver-specific deletion of mechanistic target of rapamycin does not protect against acetaminophen-induced liver injury in mice. Liver Res. 2021;5:79-87 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 6b
Tulotta C, Lefley D, Moore C, Amariutei A, Spicer Hadlington A, Quayle L, et al. IL-1B drives opposing responses in primary tumours and bone metastases; harnessing combination therapies to improve outcome in breast cancer. NPJ Breast Cancer. 2021;7:95 pubmed 出版商
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Hatzopoulos G, Kükenshöner T, Banterle N, Favez T, Flückiger I, Hamel V, et al. Tuning SAS-6 architecture with monobodies impairs distinct steps of centriole assembly. Nat Commun. 2021;12:3805 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50; 图 2g
Prokakis E, Dyas A, Grün R, Fritzsche S, Bedi U, Kazerouni Z, et al. USP22 promotes HER2-driven mammary carcinoma aggressiveness by suppressing the unfolded protein response. Oncogene. 2021;40:4004-4018 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 3f
Wang S, Li S, Li Y, Jiang Q, Li X, Wang Y, et al. Non-muscle myosin heavy chain 9 maintains intestinal homeostasis by preventing epithelium necroptosis and colitis adenoma formation. Stem Cell Reports. 2021;16:1290-1301 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 s4c
  • 免疫印迹; 小鼠; 1:500; 图 3j
  • 免疫印迹; 人类; 1:500; 图 1b
Ryu Y, Lee D, Shim J, Park J, Kim Y, Choi S, et al. KY19382, a novel activator of Wnt/β-catenin signalling, promotes hair regrowth and hair follicle neogenesis. Br J Pharmacol. 2021;178:2533-2546 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s3-4d
Watts L, Natsume T, Saito Y, Garzón J, Dong Q, Boteva L, et al. The RIF1-long splice variant promotes G1 phase 53BP1 nuclear bodies to protect against replication stress. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 图 8
Centrone M, Gena P, Ranieri M, Di Mise A, D Agostino M, Mastrodonato M, et al. In Vitro and In Vivo Nutraceutical Characterization of Two Chickpea Accessions: Differential Effects on Hepatic Lipid Over-Accumulation. Antioxidants (Basel). 2020;9: pubmed 出版商
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Sanz Gómez N, de Pedro I, Ortigosa B, Santamaria D, Malumbres M, de Carcer G, et al. Squamous differentiation requires G2/mitosis slippage to avoid apoptosis. Cell Death Differ. 2020;27:2451-2467 pubmed 出版商
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Wutz G, Ladurner R, St Hilaire B, Stocsits R, Nagasaka K, Pignard B, et al. ESCO1 and CTCF enable formation of long chromatin loops by protecting cohesinSTAG1 from WAPL. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Lai S, Lin H, Liu Y, Yang L, Lu D. Monocarboxylate Transporter 4 Regulates Glioblastoma Motility and Monocyte Binding Ability. Cancers (Basel). 2020;12: pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:800; 图 9c
Zhang Y, Mao X, Chen W, Guo X, Yu L, Jiang F, et al. A Discovery of Clinically Approved Formula FBRP for Repositioning to Treat HCC by Inhibiting PI3K/AKT/NF-κB Activation. Mol Ther Nucleic Acids. 2020;19:890-904 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 s8
Famulari E, Navarro Tableros V, Herrera Sanchez M, Bortolussi G, Gai M, Conti L, et al. Human liver stem cells express UGT1A1 and improve phenotype of immunocompromised Crigler Najjar syndrome type I mice. Sci Rep. 2020;10:887 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 3d, 3e
Li C, Chen W, Wang J, Xia M, Jia Z, Guo C, et al. Nicotinamide riboside rescues angiotensin II-induced cerebral small vessel disease in mice. CNS Neurosci Ther. 2020;26:438-447 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 3d
Francis R, Guo H, Streutker C, Ahmed M, Yung T, Dirks P, et al. Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer. Sci Adv. 2019;5:eaax8898 pubmed 出版商
  • 免疫印迹; 人类; 图 2h
Sarek G, Kotsantis P, Ruis P, Van Ly D, Margalef P, Borel V, et al. CDK phosphorylation of TRF2 controls t-loop dynamics during the cell cycle. Nature. 2019;: pubmed 出版商
  • 免疫印迹; 人类; 图 5e
Xu M, Qin J, Wang L, Lee H, Kao C, Liu D, et al. Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway. Sci Adv. 2019;5:eaax6366 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Wessel S, Mohni K, Luzwick J, Dungrawala H, Cortez D. Functional Analysis of the Replication Fork Proteome Identifies BET Proteins as PCNA Regulators. Cell Rep. 2019;28:3497-3509.e4 pubmed 出版商
  • 免疫组化-石蜡切片; 大西洋鳉; 1:100; 图 4
Szymkowicz D, Sims K, Schwendinger K, Tatnall C, Powell R, Bruce T, et al. Exposure to arsenic during embryogenesis impairs olfactory sensory neuron differentiation and function into adulthood. Toxicology. 2019;420:73-84 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 5a
Han Y, Feng H, Sun J, Liang X, Wang Z, Xing W, et al. Lkb1 deletion in periosteal mesenchymal progenitors induces osteogenic tumors through mTORC1 activation. J Clin Invest. 2019;130: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 1a
  • 免疫印迹; 人类; 1:3000; 图 1c
Jeong W, Park J, Kim W, Ro E, Jeon S, Lee S, et al. WDR76 is a RAS binding protein that functions as a tumor suppressor via RAS degradation. Nat Commun. 2019;10:295 pubmed 出版商
  • 免疫印迹; 人类; 图 7i
Xia J, Chiu L, Nehring R, Bravo Núñez M, Mei Q, Perez M, et al. Bacteria-to-Human Protein Networks Reveal Origins of Endogenous DNA Damage. Cell. 2019;176:127-143.e24 pubmed 出版商
  • 免疫印迹; 人类; 图 3d
Moquin D, Genois M, Zhang J, Ouyang J, Yadav T, Buisson R, et al. Localized protein biotinylation at DNA damage sites identifies ZPET, a repressor of homologous recombination. Genes Dev. 2019;33:75-89 pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Mohni K, Wessel S, Zhao R, Wojciechowski A, Luzwick J, Layden H, et al. HMCES Maintains Genome Integrity by Shielding Abasic Sites in Single-Strand DNA. Cell. 2019;176:144-153.e13 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 1:1000; 图 4a
Russell J, Lu W, Okabe H, Abrams M, Oertel M, Poddar M, et al. Hepatocyte-Specific β-Catenin Deletion During Severe Liver Injury Provokes Cholangiocytes to Differentiate Into Hepatocytes. Hepatology. 2019;69:742-759 pubmed 出版商
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Saldivar J, Hamperl S, Bocek M, Chung M, Bass T, Cisneros Soberanis F, et al. An intrinsic S/G2 checkpoint enforced by ATR. Science. 2018;361:806-810 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Bornelöv S, Reynolds N, Xenophontos M, Gharbi S, Johnstone E, Floyd R, et al. The Nucleosome Remodeling and Deacetylation Complex Modulates Chromatin Structure at Sites of Active Transcription to Fine-Tune Gene Expression. Mol Cell. 2018;71:56-72.e4 pubmed 出版商
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Li M, Xu X, Chang C, Zheng L, Shen B, Liu Y. SUMO2 conjugation of PCNA facilitates chromatin remodeling to resolve transcription-replication conflicts. Nat Commun. 2018;9:2706 pubmed 出版商
  • 免疫印迹; 人类; 图 4f
  • 免疫印迹; 小鼠; 图 s14e, s15f
Ruess D, Heynen G, Ciecielski K, Ai J, Berninger A, Kabacaoglu D, et al. Mutant KRAS-driven cancers depend on PTPN11/SHP2 phosphatase. Nat Med. 2018;24:954-960 pubmed 出版商
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Lei T, Zhang P, Zhang X, Xiao X, Zhang J, Qiu T, et al. Cyclin K regulates prereplicative complex assembly to promote mammalian cell proliferation. Nat Commun. 2018;9:1876 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 3a
  • 免疫印迹; 小鼠; 图 3b
Park J, Kim I, Choi J, Lim H, Shin J, Kim Y, et al. AHNAK Loss in Mice Promotes Type II Pneumocyte Hyperplasia and Lung Tumor Development. Mol Cancer Res. 2018;16:1287-1298 pubmed 出版商
  • 免疫印迹; 小鼠; 图 e10h
Tusi B, Wolock S, Weinreb C, Hwang Y, Hidalgo D, Zilionis R, et al. Population snapshots predict early haematopoietic and erythroid hierarchies. Nature. 2018;555:54-60 pubmed 出版商
  • proximity ligation assay; 小鼠; 图 7d
Margalef P, Kotsantis P, Borel V, Bellelli R, Panier S, Boulton S. Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe. Cell. 2018;172:439-453.e14 pubmed 出版商
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Somyajit K, Gupta R, Sedlackova H, Neelsen K, Ochs F, Rask M, et al. Redox-sensitive alteration of replisome architecture safeguards genome integrity. Science. 2017;358:797-802 pubmed 出版商
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Ong D, Hu B, Ho Y, Sauvé C, Bristow C, Wang Q, et al. PAF promotes stemness and radioresistance of glioma stem cells. Proc Natl Acad Sci U S A. 2017;114:E9086-E9095 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:5000; 图 5f
  • 免疫组化; 小鼠; 1:5000; 图 5f
Otto T, Candido S, Pilarz M, Sicinska E, Bronson R, Bowden M, et al. Cell cycle-targeting microRNAs promote differentiation by enforcing cell-cycle exit. Proc Natl Acad Sci U S A. 2017;114:10660-10665 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Oblinger J, Burns S, Huang J, Pan L, Ren Y, Shen R, et al. Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation. Exp Neurol. 2018;299:299-307 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Bj Rås K, Sousa M, Sharma A, Fonseca D, S Gaard C, Bj Rås M, et al. Monitoring of the spatial and temporal dynamics of BER/SSBR pathway proteins, including MYH, UNG2, MPG, NTH1 and NEIL1-3, during DNA replication. Nucleic Acids Res. 2017;45:8291-8301 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 3b
Young C, Eckert R, Adhikary G, Crumrine D, Elias P, Blumenberg M, et al. Embryonic AP1 Transcription Factor Deficiency Causes a Collodion Baby-Like Phenotype. J Invest Dermatol. 2017;137:1868-1877 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 6c
Yoon C, Cho S, Chang K, Park D, Ryeom S, Yoon S. Role of Rac1 Pathway in Epithelial-to-Mesenchymal Transition and Cancer Stem-like Cell Phenotypes in Gastric Adenocarcinoma. Mol Cancer Res. 2017;15:1106-1116 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 5c
Yuan X, Sun X, Shi X, Jiang C, Yu D, Zhang W, et al. USP39 regulates the growth of SMMC-7721 cells via FoxM1. Exp Ther Med. 2017;13:1506-1513 pubmed 出版商
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Kang H, Park J, Choi K, Kim Y, Choi H, Jung C, et al. Chemical screening identifies ATM as a target for alleviating senescence. Nat Chem Biol. 2017;13:616-623 pubmed 出版商
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Xiang Y, Laurent B, Hsu C, Nachtergaele S, Lu Z, Sheng W, et al. RNA m6A methylation regulates the ultraviolet-induced DNA damage response. Nature. 2017;543:573-576 pubmed 出版商
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Martín Ibáñez R, Pardo M, Giralt A, Miguez A, Guardia I, Marion Poll L, et al. Helios expression coordinates the development of a subset of striatopallidal medium spiny neurons. Development. 2017;144:1566-1577 pubmed 出版商
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Li K, Mo C, Gong D, Chen Y, Huang Z, Li Y, et al. DDX17 nucleocytoplasmic shuttling promotes acquired gefitinib resistance in non-small cell lung cancer cells via activation of β-catenin. Cancer Lett. 2017;400:194-202 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 图 4a
Ibrahim M, Elwan W. Role of topical dehydroepiandrosterone in ameliorating isotretinoin-induced Meibomian gland dysfunction in adult male albino rat. Ann Anat. 2017;211:78-87 pubmed 出版商
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Maskey R, Flatten K, Sieben C, Peterson K, Baker D, Nam H, et al. Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis. Nucleic Acids Res. 2017;45:4564-4576 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 1d
Dietsch F, Donzeau M, Cordonnier A, Weiss E, Chatton B, Vigneron M. A fast method for analyzing essential protein mutants in human cells. Biotechniques. 2017;62:80-82 pubmed 出版商
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Liu Z, Yanagisawa K, Griesing S, Iwai M, Kano K, Hotta N, et al. TTF-1/NKX2-1 binds to DDB1 and confers replication stress resistance to lung adenocarcinomas. Oncogene. 2017;36:3740-3748 pubmed 出版商
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Tu Y, Liu H, Zhu X, Shen H, Ma X, Wang F, et al. Ataxin-3 promotes genome integrity by stabilizing Chk1. Nucleic Acids Res. 2017;45:4532-4549 pubmed 出版商
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Ren W, Yin J, Xiao H, Chen S, Liu G, Tan B, et al. Intestinal Microbiota-Derived GABA Mediates Interleukin-17 Expression during Enterotoxigenic Escherichia coli Infection. Front Immunol. 2016;7:685 pubmed 出版商
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Shi N, Li C, Cui X, Tomarev S, Chen S. Olfactomedin 2 Regulates Smooth Muscle Phenotypic Modulation and Vascular Remodeling Through Mediating Runt-Related Transcription Factor 2 Binding to Serum Response Factor. Arterioscler Thromb Vasc Biol. 2017;37:446-454 pubmed 出版商
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Mórocz M, Zsigmond E, Toth R, Enyedi M, Pintér L, Haracska L. DNA-dependent protease activity of human Spartan facilitates replication of DNA-protein crosslink-containing DNA. Nucleic Acids Res. 2017;45:3172-3188 pubmed 出版商
  • dot blot; 人类; 1:5000; 图 2a
Li C, Miao Y, Lingeman R, Hickey R, Malkas L. Partial Purification of a Megadalton DNA Replication Complex by Free Flow Electrophoresis. PLoS ONE. 2016;11:e0169259 pubmed 出版商
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Jo U, Cai W, Wang J, Kwon Y, D Andrea A, Kim H. PCNA-Dependent Cleavage and Degradation of SDE2 Regulates Response to Replication Stress. PLoS Genet. 2016;12:e1006465 pubmed 出版商
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Despras E, Sittewelle M, Pouvelle C, Delrieu N, Cordonnier A, Kannouche P. Rad18-dependent SUMOylation of human specialized DNA polymerase eta is required to prevent under-replicated DNA. Nat Commun. 2016;7:13326 pubmed 出版商
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Wu R, Wang Z, Zhang H, Gan H, Zhang Z. H3K9me3 demethylase Kdm4d facilitates the formation of pre-initiative complex and regulates DNA replication. Nucleic Acids Res. 2017;45:169-180 pubmed 出版商
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Kehrli K, Phelps M, Lazarchuk P, Chen E, Monnat R, Sidorova J. Class I Histone Deacetylase HDAC1 and WRN RECQ Helicase Contribute Additively to Protect Replication Forks upon Hydroxyurea-induced Arrest. J Biol Chem. 2016;291:24487-24503 pubmed
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Gao Y, Li J, Qiao N, Meng Q, Zhang M, Wang X, et al. Adrenomedullin blockade suppresses sunitinib-resistant renal cell carcinoma growth by targeting the ERK/MAPK pathway. Oncotarget. 2016;7:63374-63387 pubmed 出版商
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Urban V, Dobrovolna J, Huhn D, Fryzelkova J, Bartek J, Janscak P. RECQ5 helicase promotes resolution of conflicts between replication and transcription in human cells. J Cell Biol. 2016;214:401-15 pubmed 出版商
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Engel N, Ali I, Adamus A, Frank M, Dad A, Ali S, et al. Antitumor evaluation of two selected Pakistani plant extracts on human bone and breast cancer cell lines. BMC Complement Altern Med. 2016;16:244 pubmed 出版商
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Chen C, Tsao N, Huang L, Yen Y, Liu X, Lehman C, et al. The Impact of dUTPase on Ribonucleotide Reductase-Induced Genome Instability in Cancer Cells. Cell Rep. 2016;16:1287-1299 pubmed 出版商
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Yang C, Suzuki M, Yamakawa S, Uno S, Ishii A, Yamazaki S, et al. Claspin recruits Cdc7 kinase for initiation of DNA replication in human cells. Nat Commun. 2016;7:12135 pubmed 出版商
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Gao Y, Mutter Rottmayer E, Greenwalt A, Goldfarb D, Yan F, Yang Y, et al. A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis. Nat Commun. 2016;7:12105 pubmed 出版商
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Guan C, Zhang J, Zhang J, Shi H, Ni R. Enhanced expression of early mitotic inhibitor-1 predicts a poor prognosis in esophageal squamous cell carcinoma patients. Oncol Lett. 2016;12:114-120 pubmed
  • 免疫组化; 小鼠; 1:100; 图 1
Barrionuevo F, Hurtado A, Kim G, Real F, Bakkali M, Kopp J, et al. Sox9 and Sox8 protect the adult testis from male-to-female genetic reprogramming and complete degeneration. elife. 2016;5: pubmed 出版商
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Kais Z, Rondinelli B, Holmes A, O Leary C, Kozono D, D Andrea A, et al. FANCD2 Maintains Fork Stability in BRCA1/2-Deficient Tumors and Promotes Alternative End-Joining DNA Repair. Cell Rep. 2016;15:2488-99 pubmed 出版商
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Wisnovsky S, Jean S, Kelley S. Mitochondrial DNA repair and replication proteins revealed by targeted chemical probes. Nat Chem Biol. 2016;12:567-73 pubmed 出版商
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Chesnokova V, Zonis S, Zhou C, Recouvreux M, Ben Shlomo A, Araki T, et al. Growth hormone is permissive for neoplastic colon growth. Proc Natl Acad Sci U S A. 2016;113:E3250-9 pubmed 出版商
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Romanello M, Schiavone D, Frey A, Sale J. Histone H3.3 promotes IgV gene diversification by enhancing formation of AID-accessible single-stranded DNA. EMBO J. 2016;35:1452-64 pubmed 出版商
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Ren W, Yin J, Chen S, Duan J, Liu G, Li T, et al. Proteome analysis for the global proteins in the jejunum tissues of enterotoxigenic Escherichia coli -infected piglets. Sci Rep. 2016;6:25640 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1
Ho T, Guilbaud G, Blow J, Sale J, Watson C. The KRAB Zinc Finger Protein Roma/Zfp157 Is a Critical Regulator of Cell-Cycle Progression and Genomic Stability. Cell Rep. 2016;15:724-734 pubmed 出版商
  • 免疫组化-自由浮动切片; 大鼠; 1:250; 图 2a
Mohr M, Garcia F, Doncarlos L, Sisk C. Neurons and Glial Cells Are Added to the Female Rat Anteroventral Periventricular Nucleus During Puberty. Endocrinology. 2016;157:2393-402 pubmed 出版商
  • 免疫组化; 日本大米鱼; 1:500; 图 3
Lust K, Sinn R, Pérez Saturnino A, Centanin L, Wittbrodt J. De novo neurogenesis by targeted expression of atoh7 to Müller glia cells. Development. 2016;143:1874-83 pubmed 出版商
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Macritchie N, Volpert G, Al Washih M, Watson D, Futerman A, Kennedy S, et al. Effect of the sphingosine kinase 1 selective inhibitor, PF-543 on arterial and cardiac remodelling in a hypoxic model of pulmonary arterial hypertension. Cell Signal. 2016;28:946-55 pubmed 出版商
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Yin Y, Ren X, Smith C, Guo Q, Malabunga M, Guernah I, et al. Inhibition of fibroblast growth factor receptor 3-dependent lung adenocarcinoma with a human monoclonal antibody. Dis Model Mech. 2016;9:563-71 pubmed 出版商
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Seidel P, Remus M, Delacher M, Grigaravicius P, Reuss D, Frappart L, et al. Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis. Oncotarget. 2016;7:23006-18 pubmed 出版商
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产品信息
产品名称 :
增殖细胞核抗原(PC10)抗体
基因名称 :
增殖细胞核抗原
规格 :
200微克/毫升
目录号 :
sc-56
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
增殖细胞核抗原
反应物种 :
m, r, h, insect, S. pombe
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), FCM
表位 :
FL(大鼠)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
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