产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
PKR(B-10)抗体
目录 :
sc-6282
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
B-10
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 25
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:200; 图 2a
Goodman D, Pretto C, Krepostman T, Carnahan K, Spindler K. Enhanced Replication of Mouse Adenovirus Type 1 following Virus-Induced Degradation of Protein Kinase R (PKR). MBio. 2019;10: pubmed 出版商
  • 免疫印迹; 人类; 图 5
Ren S, Wang J, Chen T, Li H, Wan Y, Peng N, et al. Hepatitis B Virus Stimulated Fibronectin Facilitates Viral Maintenance and Replication through Two Distinct Mechanisms. PLoS ONE. 2016;11:e0152721 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Oh S, Onomoto K, Wakimoto M, Onoguchi K, Ishidate F, Fujiwara T, et al. Leader-Containing Uncapped Viral Transcript Activates RIG-I in Antiviral Stress Granules. PLoS Pathog. 2016;12:e1005444 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Lancaster G, Kammoun H, Kraakman M, Kowalski G, Bruce C, Febbraio M. PKR is not obligatory for high-fat diet-induced obesity and its associated metabolic and inflammatory complications. Nat Commun. 2016;7:10626 pubmed 出版商
  • 免疫印迹; 人类; 图 4
  • 免疫印迹; 小鼠; 图 4
So J, Cho S, Min S, Kimball S, Lee A. IRE1α-Dependent Decay of CReP/Ppp1r15b mRNA Increases Eukaryotic Initiation Factor 2α Phosphorylation and Suppresses Protein Synthesis. Mol Cell Biol. 2015;35:2761-70 pubmed 出版商
  • 免疫印迹基因敲除验证; 小鼠; 图 5c
Liu X, Bennett R, Cheng X, Byrne M, Reinhard M, May W. PKR regulates proliferation, differentiation, and survival of murine hematopoietic stem/progenitor cells. Blood. 2013;121:3364-74 pubmed 出版商
Hato T, Maier B, Syed F, Myslinski J, Zollman A, Plotkin Z, et al. Bacterial sepsis triggers an antiviral response that causes translation shutdown. J Clin Invest. 2019;129:296-309 pubmed 出版商
Cubas Gaona L, Diaz Beneitez E, Ciscar M, Rodriguez J, Rodriguez D. Exacerbated Apoptosis of Cells Infected with Infectious Bursal Disease Virus upon Exposure to Interferon Alpha. J Virol. 2018;92: pubmed 出版商
Wang D, de Weerd N, Willard B, Polekhina G, Williams B, Sadler A. Auto-phosphorylation Represses Protein Kinase R Activity. Sci Rep. 2017;7:44340 pubmed 出版商
Zhang M, Qi Y, Li H, Cui J, Dai L, Frank J, et al. AIM2 inflammasome mediates Arsenic-induced secretion of IL-1 ? and IL-18. Oncoimmunology. 2016;5:e1160182 pubmed 出版商
Li H, Chen J, Qi Y, Dai L, Zhang M, Frank J, et al. Deficient PKR in RAX/PKR Association Ameliorates Ethanol-Induced Neurotoxicity in the Developing Cerebellum. Cerebellum. 2015;14:386-97 pubmed 出版商
Brennan G, Kitzman J, Rothenburg S, Shendure J, Geballe A. Adaptive gene amplification as an intermediate step in the expansion of virus host range. PLoS Pathog. 2014;10:e1004002 pubmed 出版商
Li W, Li J, Sama A, Wang H. Carbenoxolone blocks endotoxin-induced protein kinase R (PKR) activation and high mobility group box 1 (HMGB1) release. Mol Med. 2013;19:203-11 pubmed 出版商
He Y, Franchi L, Nunez G. The protein kinase PKR is critical for LPS-induced iNOS production but dispensable for inflammasome activation in macrophages. Eur J Immunol. 2013;43:1147-52 pubmed 出版商
Onomoto K, Jogi M, Yoo J, Narita R, Morimoto S, Takemura A, et al. Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity. PLoS ONE. 2012;7:e43031 pubmed 出版商
Clavarino G, Cláudio N, Couderc T, Dalet A, Judith D, Camosseto V, et al. Induction of GADD34 is necessary for dsRNA-dependent interferon-? production and participates in the control of Chikungunya virus infection. PLoS Pathog. 2012;8:e1002708 pubmed 出版商
Child S, Brennan G, Braggin J, Geballe A. Species specificity of protein kinase r antagonism by cytomegalovirus TRS1 genes. J Virol. 2012;86:3880-9 pubmed 出版商
Maestre A, Garzón A, Rodriguez D. Equine torovirus (BEV) induces caspase-mediated apoptosis in infected cells. PLoS ONE. 2011;6:e20972 pubmed 出版商
Guan Z, Liu D, Mi S, Zhang J, Ye Q, Wang M, et al. Interaction of Hsp40 with influenza virus M2 protein: implications for PKR signaling pathway. Protein Cell. 2010;1:944-55 pubmed 出版商
Groskreutz D, Babor E, Monick M, Varga S, Hunninghake G. Respiratory syncytial virus limits alpha subunit of eukaryotic translation initiation factor 2 (eIF2alpha) phosphorylation to maintain translation and viral replication. J Biol Chem. 2010;285:24023-31 pubmed 出版商
Child S, Geballe A. Binding and relocalization of protein kinase R by murine cytomegalovirus. J Virol. 2009;83:1790-9 pubmed 出版商
Chen H, Wang L, D Mello S. A chemical compound commonly used to inhibit PKR, {8-(imidazol-4-ylmethylene)-6H-azolidino[5,4-g] benzothiazol-7-one}, protects neurons by inhibiting cyclin-dependent kinase. Eur J Neurosci. 2008;28:2003-16 pubmed 出版商
Tamassia N, Le Moigne V, Rossato M, Donini M, McCartney S, Calzetti F, et al. Activation of an immunoregulatory and antiviral gene expression program in poly(I:C)-transfected human neutrophils. J Immunol. 2008;181:6563-73 pubmed
Baltzis D, Pluquet O, Papadakis A, Kazemi S, Qu L, Koromilas A. The eIF2alpha kinases PERK and PKR activate glycogen synthase kinase 3 to promote the proteasomal degradation of p53. J Biol Chem. 2007;282:31675-87 pubmed
Fleming J, Shen G, Holloway S, Davis M, Brekken R. Molecular consequences of silencing mutant K-ras in pancreatic cancer cells: justification for K-ras-directed therapy. Mol Cancer Res. 2005;3:413-23 pubmed
产品信息
产品名称 :
PKR(B-10)抗体
基因名称 :
EIF2AK2
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-6282
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
PKR
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P)
表位 :
1-515(小鼠)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。