产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
Raf-1 (E-10) Antibody
目录 :
sc-7267
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
E-10
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, proximity ligation assay
更多信息或购买 :
文章摘录数: 31
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 3b
Qi Z, Xu H, Zhang S, Xu J, Li S, Gao H, et al. RIPK4/PEBP1 axis promotes pancreatic cancer cell migration and invasion by activating RAF1/MEK/ERK signaling. Int J Oncol. 2018;52:1105-1116 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Ferraiuolo R, Tubman J, Sinha I, Hamm C, Porter L. The cyclin-like protein, SPY1, regulates the ER? and ERK1/2 pathways promoting tamoxifen resistance. Oncotarget. 2017;8:23337-23352 pubmed 出版商
  • 免疫沉淀; 人类; 1:1000; 图 4
  • 免疫沉淀; 小鼠; 1:1000; 图 2
Bunda S, Burrell K, Heir P, Zeng L, Alamsahebpour A, Kano Y, et al. Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis. Nat Commun. 2015;6:8859 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Boswell B, Musil L. Synergistic interaction between the fibroblast growth factor and bone morphogenetic protein signaling pathways in lens cells. Mol Biol Cell. 2015;26:2561-72 pubmed 出版商
  • proximity ligation assay; 人类; 1:100; 图 8
Brobeil A, Kämmerer F, Tag C, Steger K, Gattenlöhner S, Wimmer M. PTPIP51—A New RelA-tionship with the NFκB Signaling Pathway. Biomolecules. 2015;5:485-504 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 6g
Yang Z, Zheng B, Zhang Y, He M, Zhang X, Ma D, et al. miR-155-dependent regulation of mammalian sterile 20-like kinase 2 (MST2) coordinates inflammation, oxidative stress and proliferation in vascular smooth muscle cells. Biochim Biophys Acta. 2015;1852:1477-89 pubmed 出版商
  • proximity ligation assay; 小鼠
  • 免疫组化-石蜡切片; 小鼠
Brobeil A, Viard M, Petri M, Steger K, Tag C, Wimmer M. Memory and PTPIP51--a new protein in hippocampus and cerebellum. Mol Cell Neurosci. 2015;64:61-73 pubmed 出版商
  • 免疫印迹; 人类
Petti C, Picco G, Martelli M, Trisolini E, Bucci E, Perera T, et al. Truncated RAF kinases drive resistance to MET inhibition in MET-addicted cancer cells. Oncotarget. 2015;6:221-33 pubmed
  • proximity ligation assay; 人类; 1:100; 图 9d
Brobeil A, Graf M, Eiber M, Wimmer M. Interaction of PTPIP51 with Tubulin, CGI-99 and Nuf2 During Cell Cycle Progression. Biomolecules. 2012;2:122-42 pubmed 出版商
Hinterseher I, Schworer C, Lillvis J, Stahl E, Erdman R, Gatalica Z, et al. Immunohistochemical analysis of the natural killer cell cytotoxicity pathway in human abdominal aortic aneurysms. Int J Mol Sci. 2015;16:11196-212 pubmed 出版商
Wada M, Horinaka M, Yamazaki T, Katoh N, Sakai T. The dual RAF/MEK inhibitor CH5126766/RO5126766 may be a potential therapy for RAS-mutated tumor cells. PLoS ONE. 2014;9:e113217 pubmed 出版商
Minna E, Romeo P, De Cecco L, Dugo M, Cassinelli G, Pilotti S, et al. miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma. Oncotarget. 2014;5:2513-28 pubmed
Brobeil A, Bobrich M, Tag C, Wimmer M. PTPIP51 in protein interactions: regulation and in situ interacting partners. Cell Biochem Biophys. 2012;63:211-22 pubmed 出版商
Zuco V, De Cesare M, Cincinelli R, Nannei R, Pisano C, Zaffaroni N, et al. Synergistic antitumor effects of novel HDAC inhibitors and paclitaxel in vitro and in vivo. PLoS ONE. 2011;6:e29085 pubmed 出版商
Balgi A, Diering G, Donohue E, Lam K, Fonseca B, Zimmerman C, et al. Regulation of mTORC1 signaling by pH. PLoS ONE. 2011;6:e21549 pubmed 出版商
Yang H, Higgins B, Kolinsky K, Packman K, Go Z, Iyer R, et al. RG7204 (PLX4032), a selective BRAFV600E inhibitor, displays potent antitumor activity in preclinical melanoma models. Cancer Res. 2010;70:5518-27 pubmed 出版商
Halaban R, Zhang W, Bacchiocchi A, Cheng E, Parisi F, Ariyan S, et al. PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells. Pigment Cell Melanoma Res. 2010;23:190-200 pubmed 出版商
Shu F, Ramineni S, Hepler J. RGS14 is a multifunctional scaffold that integrates G protein and Ras/Raf MAPkinase signalling pathways. Cell Signal. 2010;22:366-76 pubmed 出版商
Koch P, Petri M, Paradowska A, Stenzinger A, Sturm K, Steger K, et al. PTPIP51 mRNA and protein expression in tissue microarrays and promoter methylation of benign prostate hyperplasia and prostate carcinoma. Prostate. 2009;69:1751-62 pubmed 出版商
Webster R, Giles K, Price K, Zhang P, Mattick J, Leedman P. Regulation of epidermal growth factor receptor signaling in human cancer cells by microRNA-7. J Biol Chem. 2009;284:5731-41 pubmed 出版商
Zuco V, Zunino F. Cyclic pifithrin-alpha sensitizes wild type p53 tumor cells to antimicrotubule agent-induced apoptosis. Neoplasia. 2008;10:587-96 pubmed
Mao X, Orchard G, Mitchell T, Oyama N, Russell Jones R, Vermeer M, et al. A genomic and expression study of AP-1 in primary cutaneous T-cell lymphoma: evidence for dysregulated expression of JUNB and JUND in MF and SS. J Cutan Pathol. 2008;35:899-910 pubmed 出版商
Mao X, Orchard G. Abnormal AP-1 protein expression in primary cutaneous B-cell lymphomas. Br J Dermatol. 2008;159:145-51 pubmed 出版商
Engebretsen B, Irwin D, Valdez M, O Donovan M, Tucker A, van Patot M. Acute hypobaric hypoxia (5486 m) induces greater pulmonary HIF-1 activation in hilltop compared to madison rats. High Alt Med Biol. 2007;8:312-21 pubmed
Provot S, Nachtrab G, Paruch J, Chen A, Silva A, Kronenberg H. A-raf and B-raf are dispensable for normal endochondral bone development, and parathyroid hormone-related peptide suppresses extracellular signal-regulated kinase activation in hypertrophic chondrocytes. Mol Cell Biol. 2008;28:344-57 pubmed
Mao X, Orchard G, Russell Jones R, Whittaker S. Abnormal activator protein 1 transcription factor expression in CD30-positive cutaneous large-cell lymphomas. Br J Dermatol. 2007;157:914-21 pubmed
Methi T, Ngai J, Vang T, Torgersen K, Tasken K. Hypophosphorylated TCR/CD3zeta signals through a Grb2-SOS1-Ras pathway in Lck knockdown cells. Eur J Immunol. 2007;37:2539-48 pubmed
Yokoyama T, Takano K, Yoshida A, Katada F, Sun P, Takenawa T, et al. DA-Raf1, a competent intrinsic dominant-negative antagonist of the Ras-ERK pathway, is required for myogenic differentiation. J Cell Biol. 2007;177:781-93 pubmed
Romanenko A, Morimura K, Kinoshita A, Wanibuchi H, Takahashi S, Zaparin W, et al. Upregulation of fibroblast growth factor receptor 3 and epidermal growth factor receptors, in association with Raf-1, in urothelial dysplasia and carcinoma in situ after the Chernobyl accident. Cancer Sci. 2006;97:1168-74 pubmed
Adams D, Coffee R, Zhang H, Pelech S, Strack S, Wadzinski B. Positive regulation of Raf1-MEK1/2-ERK1/2 signaling by protein serine/threonine phosphatase 2A holoenzymes. J Biol Chem. 2005;280:42644-54 pubmed
Mukherjee R, Bartlett J, Krishna N, Underwood M, Edwards J. Raf-1 expression may influence progression to androgen insensitive prostate cancer. Prostate. 2005;64:101-7 pubmed
产品信息
产品名称 :
Raf-1 (E-10) Antibody
基因名称 :
RAF1
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-7267
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
Raf-1
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), FCM, 酶联免疫吸附测定
表位 :
C末端(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。