产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
GSK-3alpha/乙(0011-A)抗体
目录 :
sc-7291
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
0011-A
反应物种 :
衣藻, 人类, 小鼠, 大鼠,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, reverse phase protein lysate microarray, 其他
更多信息或购买 :
文章摘录数: 51
出版应用/物种/样本/稀释参考文献
  • 其他; 人类; 图 4c
Ng P, Li J, Jeong K, Shao S, Chen H, Tsang Y, et al. Systematic Functional Annotation of Somatic Mutations in Cancer. Cancer Cell. 2018;33:450-462.e10 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 st6
Cherniack A, Shen H, Walter V, Stewart C, Murray B, Bowlby R, et al. Integrated Molecular Characterization of Uterine Carcinosarcoma. Cancer Cell. 2017;31:411-423 pubmed 出版商
  • reverse phase protein lysate microarray; 人类; 图 3a
. Integrated genomic and molecular characterization of cervical cancer. Nature. 2017;543:378-384 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 3b
Granato M, Rizzello C, Gilardini Montani M, Cuomo L, Vitillo M, Santarelli R, et al. Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways. J Nutr Biochem. 2017;41:124-136 pubmed 出版商
  • 免疫印迹; 人类
Hill S, Nesser N, Johnson Camacho K, Jeffress M, Johnson A, Boniface C, et al. Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling. Cell Syst. 2017;4:73-83.e10 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 8e
Lin K, Kao S, Lai C, Chen C, Wu C, Hsu H, et al. Tumor Suppressor Lzap Suppresses Wnt/β-Catenin Signaling to Promote Zebrafish Embryonic Ventral Cell Fates via the Suppression of Inhibitory Phosphorylation of Glycogen Synthase Kinase 3. J Biol Chem. 2015;290:29808-19 pubmed 出版商
  • 免疫细胞化学; 衣藻; 1:100; 图 5
  • 酶联免疫吸附测定; 衣藻; 1:500; 图 5
  • 免疫印迹; 衣藻; 1:500; 图 5
Kong J, Hardin K, Dinkins M, Wang G, He Q, Mujadzic T, et al. Regulation of Chlamydomonas flagella and ependymal cell motile cilia by ceramide-mediated translocation of GSK3. Mol Biol Cell. 2015;26:4451-65 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Seo M, Lee C, Cho H, You Y, Lee B, Lee J, et al. Effects of antipsychotic drugs on the expression of synapse-associated proteins in the frontal cortex of rats subjected to immobilization stress. Psychiatry Res. 2015;229:968-74 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Morra F, Luise C, Merolla F, Poser I, Visconti R, Ilardi G, et al. FBXW7 and USP7 regulate CCDC6 turnover during the cell cycle and affect cancer drugs susceptibility in NSCLC. Oncotarget. 2015;6:12697-709 pubmed
  • 免疫印迹; 人类
Giovannini C, Minguzzi M, Baglioni M, Fornari F, Giannone F, Ravaioli M, et al. Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma. Oncotarget. 2014;5:10607-20 pubmed
  • 免疫印迹; 小鼠
Young M, Brewer R, Peliciari Garcia R, Collins H, He L, Birky T, et al. Cardiomyocyte-specific BMAL1 plays critical roles in metabolism, signaling, and maintenance of contractile function of the heart. J Biol Rhythms. 2014;29:257-76 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Chu Y, Gómez Rosso L, Huang P, Wang Z, Xu Y, Yao X, et al. Liver Med23 ablation improves glucose and lipid metabolism through modulating FOXO1 activity. Cell Res. 2014;24:1250-65 pubmed 出版商
  • 免疫印迹; 人类
Xu L, Long Z, Peng F, Liu Y, Xu J, Wang C, et al. Aurora kinase a suppresses metabolic stress-induced autophagic cell death by activating mTOR signaling in breast cancer cells. Oncotarget. 2014;5:7498-511 pubmed
  • 免疫印迹; 人类
Izumi H, Kaneko Y. Trim32 facilitates degradation of MYCN on spindle poles and induces asymmetric cell division in human neuroblastoma cells. Cancer Res. 2014;74:5620-30 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, et al. YAP/TAZ incorporation in the ?-catenin destruction complex orchestrates the Wnt response. Cell. 2014;158:157-70 pubmed 出版商
Du X, He W, He H, Wang H. Beta-catenin inhibits bovine parainfluenza virus type 3 replication via innate immunity pathway. BMC Vet Res. 2020;16:72 pubmed 出版商
Adhikari A, Davie J. JARID2 and the PRC2 complex regulate skeletal muscle differentiation through regulation of canonical Wnt signaling. Epigenetics Chromatin. 2018;11:46 pubmed 出版商
de Blas E, Estañ M, Del Carmen Gómez de Frutos M, Ramos J, Del Carmen Boyano Adánez M, Aller P. Selected polyphenols potentiate the apoptotic efficacy of glycolytic inhibitors in human acute myeloid leukemia cell lines. Regulation by protein kinase activities. Cancer Cell Int. 2016;16:70 pubmed 出版商
Lu H, Gao Z, Zhao Z, Weng J, Ye J. Transient hypoxia reprograms differentiating adipocytes for enhanced insulin sensitivity and triglyceride accumulation. Int J Obes (Lond). 2016;40:121-8 pubmed 出版商
Xu R, Hu Q, Ma Q, Liu C, Wang G. The protease Omi regulates mitochondrial biogenesis through the GSK3β/PGC-1α pathway. Cell Death Dis. 2014;5:e1373 pubmed 出版商
Nicot A, Lo Verso F, Ratti F, Pilot Storck F, Streichenberger N, Sandri M, et al. Phosphorylation of NBR1 by GSK3 modulates protein aggregation. Autophagy. 2014;10:1036-53 pubmed 出版商
Alfaradhi M, Fernandez Twinn D, Martin Gronert M, Musial B, Fowden A, Ozanne S. Oxidative stress and altered lipid homeostasis in the programming of offspring fatty liver by maternal obesity. Am J Physiol Regul Integr Comp Physiol. 2014;307:R26-34 pubmed 出版商
Giovannini C, Baglioni M, Baron Toaldo M, Ventrucci C, D Adamo S, Cipone M, et al. Notch3 inhibition enhances sorafenib cytotoxic efficacy by promoting GSK3b phosphorylation and p21 down-regulation in hepatocellular carcinoma. Oncotarget. 2013;4:1618-31 pubmed
Nicastro H, Firestone G, Bjeldanes L. 3,3'-diindolylmethane rapidly and selectively inhibits hepatocyte growth factor/c-Met signaling in breast cancer cells. J Nutr Biochem. 2013;24:1882-8 pubmed 出版商
Li H, Jeong H, Choi Y, Lee S, Jeong H, Jeong T, et al. Glycogen synthase kinase 3 alpha phosphorylates and regulates the osteogenic activity of Osterix. Biochem Biophys Res Commun. 2013;434:653-8 pubmed 出版商
Zurashvili T, Cordón Barris L, Ruiz Babot G, Zhou X, Lizcano J, Gómez N, et al. Interaction of PDK1 with phosphoinositides is essential for neuronal differentiation but dispensable for neuronal survival. Mol Cell Biol. 2013;33:1027-40 pubmed 出版商
Barrell W, Szabo Rogers H, Liu K. Novel reporter alleles of GSK-3? and GSK-3?. PLoS ONE. 2012;7:e50422 pubmed 出版商
Kim S, Yang D, Myeong J, Ha K, Kim S, Park E, et al. Regulation of calcium influx and signaling pathway in cancer cells via TRPV6-Numb1 interaction. Cell Calcium. 2013;53:102-11 pubmed 出版商
Pouladi M, Brillaud E, Xie Y, Conforti P, Graham R, Ehrnhoefer D, et al. NP03, a novel low-dose lithium formulation, is neuroprotective in the YAC128 mouse model of Huntington disease. Neurobiol Dis. 2012;48:282-9 pubmed 出版商
Haines C, Harvey P, Leinwand L. Estrogens mediate cardiac hypertrophy in a stimulus-dependent manner. Endocrinology. 2012;153:4480-90 pubmed 出版商
Byun H, Jung H, Seo Y, Lee Y, Hwang S, Hwang E, et al. GSK3 inactivation is involved in mitochondrial complex IV defect in transforming growth factor (TGF) ?1-induced senescence. Exp Cell Res. 2012;318:1808-19 pubmed 出版商
Hung S, Chiang H, Wu C, Hsu M, Chen Y. Effects of herpes simplex virus type 1 infection on immune functions of human neutrophils. J Periodontal Res. 2012;47:635-44 pubmed 出版商
Dieni C, Bouffard M, Storey K. Glycogen synthase kinase-3: cryoprotection and glycogen metabolism in the freeze-tolerant wood frog. J Exp Biol. 2012;215:543-51 pubmed 出版商
Gutierrez A, Snyder E, Mariño Enríquez A, Zhang Y, Sioletic S, Kozakewich E, et al. Aberrant AKT activation drives well-differentiated liposarcoma. Proc Natl Acad Sci U S A. 2011;108:16386-91 pubmed 出版商
Kivimäe S, Yang X, Cheyette B. All Dact (Dapper/Frodo) scaffold proteins dimerize and exhibit conserved interactions with Vangl, Dvl, and serine/threonine kinases. BMC Biochem. 2011;12:33 pubmed 出版商
Hennessy B, Lu Y, Gonzalez Angulo A, Carey M, Myhre S, Ju Z, et al. A Technical Assessment of the Utility of Reverse Phase Protein Arrays for the Study of the Functional Proteome in Non-microdissected Human Breast Cancers. Clin Proteomics. 2010;6:129-51 pubmed 出版商
Riadh N, Allagui M, Bourogaa E, Vincent C, Croute F, Elfeki A. Neuroprotective and neurotrophic effects of long term lithium treatment in mouse brain. Biometals. 2011;24:747-57 pubmed 出版商
He Q, Gao Z, Yin J, Zhang J, Yun Z, Ye J. Regulation of HIF-1{alpha} activity in adipose tissue by obesity-associated factors: adipogenesis, insulin, and hypoxia. Am J Physiol Endocrinol Metab. 2011;300:E877-85 pubmed 出版商
Honda T, Yamamoto H, Ishii A, Inui M. PDZRN3 negatively regulates BMP-2-induced osteoblast differentiation through inhibition of Wnt signaling. Mol Biol Cell. 2010;21:3269-77 pubmed 出版商
Giliberto L, d Abramo C, Acker C, Davies P, D ADAMIO L. Transgenic expression of the amyloid-beta precursor protein-intracellular domain does not induce Alzheimer's Disease-like traits in vivo. PLoS ONE. 2010;5:e11609 pubmed 出版商
Ho W, Lee Y, Chang L, Chen Y, Liu T, Hung S. Effects of areca nut extract on the apoptosis pathways in human neutrophils. J Periodontal Res. 2010;45:412-20 pubmed 出版商
Ahmed S, Milner J. Basal cancer cell survival involves JNK2 suppression of a novel JNK1/c-Jun/Bcl-3 apoptotic network. PLoS ONE. 2009;4:e7305 pubmed 出版商
Yin J, Zuberi A, Gao Z, Liu D, Liu Z, Ye J. Shilianhua extract inhibits GSK-3beta and promotes glucose metabolism. Am J Physiol Endocrinol Metab. 2009;296:E1275-80 pubmed 出版商
Seo Y, Jung H, Shin H, Kim Y, Yim H, Chung H, et al. Enhanced glycogenesis is involved in cellular senescence via GSK3/GS modulation. Aging Cell. 2008;7:894-907 pubmed 出版商
Lee H, Tsai J, Liao P, Tsai W, Lin K, Chuang C, et al. Glycogen synthase kinase 3 alpha and 3 beta have distinct functions during cardiogenesis of zebrafish embryo. BMC Dev Biol. 2007;7:93 pubmed
Rider V, Isuzugawa K, Twarog M, Jones S, Cameron B, Imakawa K, et al. Progesterone initiates Wnt-beta-catenin signaling but estradiol is required for nuclear activation and synchronous proliferation of rat uterine stromal cells. J Endocrinol. 2006;191:537-48 pubmed
Krishnamurthy K, Wang G, Silva J, Condie B, Bieberich E. Ceramide regulates atypical PKCzeta/lambda-mediated cell polarity in primitive ectoderm cells. A novel function of sphingolipids in morphogenesis. J Biol Chem. 2007;282:3379-90 pubmed
Koivisto L, Jiang G, Hakkinen L, Chan B, Larjava H. HaCaT keratinocyte migration is dependent on epidermal growth factor receptor signaling and glycogen synthase kinase-3alpha. Exp Cell Res. 2006;312:2791-805 pubmed
Hébert S, Serneels L, Tolia A, Craessaerts K, Derks C, Filippov M, et al. Regulated intramembrane proteolysis of amyloid precursor protein and regulation of expression of putative target genes. EMBO Rep. 2006;7:739-45 pubmed
Morgan Lappe S, Woods K, Li Q, Anderson M, Schurdak M, Luo Y, et al. RNAi-based screening of the human kinome identifies Akt-cooperating kinases: a new approach to designing efficacious multitargeted kinase inhibitors. Oncogene. 2006;25:1340-8 pubmed
Tang X, Powelka A, Soriano N, Czech M, Guilherme A. PTEN, but not SHIP2, suppresses insulin signaling through the phosphatidylinositol 3-kinase/Akt pathway in 3T3-L1 adipocytes. J Biol Chem. 2005;280:22523-9 pubmed
产品信息
产品名称 :
GSK-3alpha/乙(0011-A)抗体
基因名称 :
GSK3A, GSK3B
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-7291
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
GSK-3alpha/乙
反应物种 :
m, r, h, 狗, 蛙
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), FCM
表位 :
1-420(X)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。