产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
核纤层蛋白A/C(636)抗体
目录 :
sc-7292
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
636
反应物种 :
人类, 小鼠, pigs
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 147
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:500; 图 5a
  • 免疫印迹; 人类; 1:1000; 图 5c
Laly A, Sliogeryte K, Pundel O, Ross R, Keeling M, Avisetti D, et al. The keratin network of intermediate filaments regulates keratinocyte rigidity sensing and nuclear mechanotransduction. Sci Adv. 2021;7: pubmed 出版商
  • 流式细胞仪; 人类; 1:100; 图 s2d
Yokoi A, Villar Prados A, Oliphint P, Zhang J, Song X, De Hoff P, et al. Mechanisms of nuclear content loading to exosomes. Sci Adv. 2019;5:eaax8849 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Jeppesen D, Fenix A, Franklin J, Higginbotham J, Zhang Q, Zimmerman L, et al. Reassessment of Exosome Composition. Cell. 2019;177:428-445.e18 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 1b
Bejarano D, Peng K, Laketa V, Börner K, Jost K, Lucic B, et al. HIV-1 nuclear import in macrophages is regulated by CPSF6-capsid interactions at the nuclear pore complex. elife. 2019;8: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:400; 图 s1c
Full F, van Gent M, Sparrer K, Chiang C, Zurenski M, Scherer M, et al. Centrosomal protein TRIM43 restricts herpesvirus infection by regulating nuclear lamina integrity. Nat Microbiol. 2019;4:164-176 pubmed 出版商
  • 免疫细胞化学; 人类; 1:2000; 图 1c
Arii J, Watanabe M, Maeda F, Tokai Nishizumi N, Chihara T, Miura M, et al. ESCRT-III mediates budding across the inner nuclear membrane and regulates its integrity. Nat Commun. 2018;9:3379 pubmed 出版商
  • 免疫印迹; 人类; 图 s5b
Melchionna R, Iapicca P, Di Modugno F, Trono P, Sperduti I, Fassan M, et al. The pattern of hMENA isoforms is regulated by TGF-?1 in pancreatic cancer and may predict patient outcome. Oncoimmunology. 2016;5:e1221556 pubmed 出版商
  • 免疫组化; 人类; 图 3a
  • 免疫印迹; 人类; 图 3b
Wu S, Pan S, Zhang L, Baines J, Roller R, Ames J, et al. Herpes Simplex Virus 1 Induces Phosphorylation and Reorganization of Lamin A/C through the γ134.5 Protein That Facilitates Nuclear Egress. J Virol. 2016;90:10414-10422 pubmed 出版商
  • 免疫印迹; 人类; 图 3c
Jinesh G, Molina J, Huang L, Laing N, Mills G, Bar Eli M, et al. Mitochondrial oligomers boost glycolysis in cancer stem cells to facilitate blebbishield-mediated transformation after apoptosis. Cell Death Discov. 2016;2:16003 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5g
Kaukonen R, Mai A, Georgiadou M, Saari M, De Franceschi N, Betz T, et al. Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Nat Commun. 2016;7:12237 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1C
Jagadish N, Parashar D, Gupta N, Agarwal S, Suri V, Kumar R, et al. Heat shock protein 70-2 (HSP70-2) is a novel therapeutic target for colorectal cancer and is associated with tumor growth. BMC Cancer. 2016;16:561 pubmed 出版商
  • 免疫印迹; 人类; 1:100; 图 s4
Calise S, Purich D, Nguyen T, Saleem D, Krueger C, Yin J, et al. 'Rod and ring' formation from IMP dehydrogenase is regulated through the one-carbon metabolic pathway. J Cell Sci. 2016;129:3042-52 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3
  • 免疫印迹; 人类; 1:1000; 图 1
Tatsuno T, Nakamura Y, Ma S, Tomosugi N, Ishigaki Y. Nonsense-mediated mRNA decay factor Upf2 exists in both the nucleoplasm and the cytoplasm. Mol Med Rep. 2016;14:655-60 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Lee J, Kuo C, Tsai S, Cheng S, Chen S, Chan H, et al. Inhibition of HDAC3- and HDAC6-Promoted Survivin Expression Plays an Important Role in SAHA-Induced Autophagy and Viability Reduction in Breast Cancer Cells. Front Pharmacol. 2016;7:81 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Hall A, Lu W, Godfrey J, Antonov A, Paicu C, Moxon S, et al. The cytoskeleton adaptor protein ankyrin-1 is upregulated by p53 following DNA damage and alters cell migration. Cell Death Dis. 2016;7:e2184 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2a
Huang Y, Peng W, Furuuchi N, DuHadaway J, Jimbo M, Pirritano A, et al. Insights from HuR biology point to potential improvement for second-line ovarian cancer therapy. Oncotarget. 2016;7:21812-24 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 1
Moiseeva O, Lopes Paciencia S, Huot G, Lessard F, Ferbeyre G. Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase. Aging (Albany NY). 2016;8:366-81 pubmed
  • 免疫细胞化学; 人类; 1:500; 图 2c
  • 免疫印迹; 人类; 1:2000; 图 4c
Moriuchi T, Kuroda M, Kusumoto F, Osumi T, Hirose F. Lamin A reassembly at the end of mitosis is regulated by its SUMO-interacting motif. Exp Cell Res. 2016;342:83-94 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Liu L, Liu X, Ren X, Tian Y, Chen Z, Xu X, et al. Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification. Sci Rep. 2016;6:21602 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Moudry P, Watanabe K, Wolanin K, Bartkova J, Wassing I, Watanabe S, et al. TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity. J Cell Biol. 2016;212:281-8 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1H
Konzack A, Jakupovic M, Kubaichuk K, Görlach A, Dombrowski F, Miinalainen I, et al. Mitochondrial Dysfunction Due to Lack of Manganese Superoxide Dismutase Promotes Hepatocarcinogenesis. Antioxid Redox Signal. 2015;23:1059-75 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 s1
Marchi S, Corricelli M, Trapani E, Bravi L, Pittaro A, Delle Monache S, et al. Defective autophagy is a key feature of cerebral cavernous malformations. EMBO Mol Med. 2015;7:1403-17 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Kim J, Sato M, Choi J, Kim H, Yeh B, Larsen J, et al. Nuclear Receptor Expression and Function in Human Lung Cancer Pathogenesis. PLoS ONE. 2015;10:e0134842 pubmed 出版商
  • 免疫细胞化学; 人类; 1:400; 图 s4c
Xu Y, Zhang H, Nguyen V, Angelopoulos N, Nunes J, Reid A, et al. LMTK3 Represses Tumor Suppressor-like Genes through Chromatin Remodeling in Breast Cancer. Cell Rep. 2015;12:837-49 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s3
  • 免疫印迹; 人类; 图 s3
Sadaie M, Dillon C, Narita M, Young A, Cairney C, Godwin L, et al. Cell-based screen for altered nuclear phenotypes reveals senescence progression in polyploid cells after Aurora kinase B inhibition. Mol Biol Cell. 2015;26:2971-85 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Moiseeva O, Lessard F, Acevedo Aquino M, Vernier M, Tsantrizos Y, Ferbeyre G. Mutant lamin A links prophase to a p53 independent senescence program. Cell Cycle. 2015;14:2408-21 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Sahu G, Farley K, El Hage N, Aiamkitsumrit B, Fassnacht R, Kashanchi F, et al. Cocaine promotes both initiation and elongation phase of HIV-1 transcription by activating NF-κB and MSK1 and inducing selective epigenetic modifications at HIV-1 LTR. Virology. 2015;483:185-202 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1c
Janes K. An analysis of critical factors for quantitative immunoblotting. Sci Signal. 2015;8:rs2 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 s7
Lelek M, Casartelli N, Pellin D, Rizzi E, Souque P, Severgnini M, et al. Chromatin organization at the nuclear pore favours HIV replication. Nat Commun. 2015;6:6483 pubmed 出版商
  • 免疫组化; 人类; 图 1
Gibbs Seymour I, Markiewicz E, Bekker Jensen S, Mailand N, Hutchison C. Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage. Aging Cell. 2015;14:162-9 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Banach Orlowska M, Szymańska E, Miaczynska M. APPL1 endocytic adaptor as a fine tuner of Dvl2-induced transcription. FEBS Lett. 2015;589:532-9 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Duque S, Arnold W, Odermatt P, Li X, Porensky P, Schmelzer L, et al. A large animal model of spinal muscular atrophy and correction of phenotype. Ann Neurol. 2015;77:399-414 pubmed 出版商
  • 免疫细胞化学; 人类
Eifler M, Uecker R, Weisbach H, Bogdanow B, Richter E, König L, et al. PUL21a-Cyclin A2 interaction is required to protect human cytomegalovirus-infected cells from the deleterious consequences of mitotic entry. PLoS Pathog. 2014;10:e1004514 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类; 图 4
Wang Y, Yang Y, Wu S, Pan S, Zhou C, Ma Y, et al. p32 is a novel target for viral protein ICP34.5 of herpes simplex virus type 1 and facilitates viral nuclear egress. J Biol Chem. 2014;289:35795-805 pubmed 出版商
  • 免疫印迹; 人类
Kuga T, Nie H, Kazami T, Satoh M, Matsushita K, Nomura F, et al. Lamin B2 prevents chromosome instability by ensuring proper mitotic chromosome segregation. Oncogenesis. 2014;3:e94 pubmed 出版商
  • 免疫印迹; 人类
Fleischmann K, Pagel P, Schmid I, Roscher A. RNAi-mediated silencing of MLL-AF9 reveals leukemia-associated downstream targets and processes. Mol Cancer. 2014;13:27 pubmed 出版商
  • 免疫印迹; 人类
Zhao X, Nogawa A, Matsunaga T, Takegami T, Nakagawa H, Ishigaki Y. Proteasome inhibitors and knockdown of SMG1 cause accumulation of Upf1 and Upf2 in human cells. Int J Oncol. 2014;44:222-8 pubmed 出版商
  • 免疫印迹; 人类
Bahammam M, Black S, Sume S, Assaggaf M, Faibish M, Trackman P. Requirement for active glycogen synthase kinase-3? in TGF-?1 upregulation of connective tissue growth factor (CCN2/CTGF) levels in human gingival fibroblasts. Am J Physiol Cell Physiol. 2013;305:C581-90 pubmed 出版商
  • 免疫印迹; pigs ; 1:40,000
Bosse K, Hans C, Zhao N, Koenig S, Huang N, Guggilam A, et al. Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease. J Mol Cell Cardiol. 2013;60:27-35 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Chatain N, Ziegler P, Fahrenkamp D, Jost E, Moriggl R, Schmitz Van de Leur H, et al. Src family kinases mediate cytoplasmic retention of activated STAT5 in BCR-ABL-positive cells. Oncogene. 2013;32:3587-97 pubmed 出版商
  • 免疫细胞化学; 人类
Clever M, Funakoshi T, Mimura Y, Takagi M, Imamoto N. The nucleoporin ELYS/Mel28 regulates nuclear envelope subdomain formation in HeLa cells. Nucleus. 2012;3:187-99 pubmed 出版商
  • 免疫印迹; 人类
Ghosh S, Choudary A, Ghosh S, Musi N, Hu Y, Li R. IKKbeta mediates cell shape-induced aromatase expression and estrogen biosynthesis in adipose stromal cells. Mol Endocrinol. 2009;23:662-70 pubmed 出版商
Tsai M, Cheng H, Nian F, Liu C, Chao N, Chiang K, et al. Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation. Acta Neuropathol Commun. 2020;8:106 pubmed 出版商
Alhuthali H, Bradshaw T, Lim K, Kam T, Seedhouse C. The natural alkaloid Jerantinine B has activity in acute myeloid leukemia cells through a mechanism involving c-Jun. BMC Cancer. 2020;20:629 pubmed 出版商
Xia Y, Pfeifer C, Zhu K, Irianto J, Liu D, Pannell K, et al. Rescue of DNA damage after constricted migration reveals a mechano-regulated threshold for cell cycle. J Cell Biol. 2019;: pubmed 出版商
Smith L, Irianto J, Xia Y, Pfeifer C, Discher D. Constricted migration modulates stem cell differentiation. Mol Biol Cell. 2019;:mbcE19020090 pubmed 出版商
Yang S, Zhang X, Qu H, Qu B, Yin X, Zhao H. Cabozantinib induces PUMA-dependent apoptosis in colon cancer cells via AKT/GSK-3β/NF-κB signaling pathway. Cancer Gene Ther. 2019;: pubmed 出版商
Ahn J, Cho M, Sohn S, Lee J. Inhibition of PP2A activity by H2O2 during mitosis disrupts nuclear envelope reassembly and alters nuclear shape. Exp Mol Med. 2019;51:64 pubmed 出版商
Zhang L, Yang Z, Huang W, Wu J. H19 potentiates let-7 family expression through reducing PTBP1 binding to their precursors in cholestasis. Cell Death Dis. 2019;10:168 pubmed 出版商
Rosso G, Liashkovich I, Shahin V. In Situ Investigation of Interrelationships Between Morphology and Biomechanics of Endothelial and Glial Cells and their Nuclei. Adv Sci (Weinh). 2019;6:1801638 pubmed 出版商
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Nobata T, Kyougoku H, Miyano T. Hematoxylin staining reveals a decrease in nucleolar diameter of pig oocytes before germinal vesicle breakdown. J Reprod Dev. 2013;59:500-5 pubmed
Sun X, Bristol J, Iwahori S, Hagemeier S, Meng Q, Barlow E, et al. Hsp90 inhibitor 17-DMAG decreases expression of conserved herpesvirus protein kinases and reduces virus production in Epstein-Barr virus-infected cells. J Virol. 2013;87:10126-38 pubmed 出版商
Vaisid T, Kosower N. Calpastatin is upregulated in non-immune neuronal cells via toll-like receptor 2 (TLR2) pathways by lipid-containing agonists. Biochim Biophys Acta. 2013;1833:2369-77 pubmed 出版商
Desimmie B, Schrijvers R, Demeulemeester J, Borrenberghs D, Weydert C, Thys W, et al. LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions. Retrovirology. 2013;10:57 pubmed 出版商
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Kuo H, Chen Y, Chang H, Jeng J, Lin E, Pan C, et al. The PML isoform IV is a negative regulator of nuclear EGFR's transcriptional activity in lung cancer. Carcinogenesis. 2013;34:1708-16 pubmed 出版商
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Liu L, Zhou Z, Huang S, Guo Y, Fan Y, Zhang J, et al. Zc3h12c inhibits vascular inflammation by repressing NF-?B activation and pro-inflammatory gene expression in endothelial cells. Biochem J. 2013;451:55-60 pubmed 出版商
Kyogoku H, Ogushi S, Miyano T. Nucleoli from two-cell embryos support the development of enucleolated germinal vesicle oocytes in the pig. Biol Reprod. 2012;87:113 pubmed 出版商
van Wielink R, Harmsen M, Martens D, Peeters B, Wijffels R, Moormann R. Mutations in the M-gene segment can substantially increase replication efficiency of NS1 deletion influenza A virus in MDCK cells. J Virol. 2012;86:12341-50 pubmed 出版商
Neumann L, Markaki Y, Mladenov E, Hoffmann D, Buiting K, Horsthemke B. The imprinted NPAP1/C15orf2 gene in the Prader-Willi syndrome region encodes a nuclear pore complex associated protein. Hum Mol Genet. 2012;21:4038-48 pubmed 出版商
Hupalowska A, Pyrzynska B, Miaczynska M. APPL1 regulates basal NF-?B activity by stabilizing NIK. J Cell Sci. 2012;125:4090-102 pubmed 出版商
Gestl E, Anne Böttger S. Cytoplasmic sequestration of the tumor suppressor p53 by a heat shock protein 70 family member, mortalin, in human colorectal adenocarcinoma cell lines. Biochem Biophys Res Commun. 2012;423:411-6 pubmed 出版商
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产品信息
产品名称 :
核纤层蛋白A/C(636)抗体
基因名称 :
LMNA
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-7292
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
核纤层蛋白A/C
反应物种 :
人类, 猪
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), FCM
表位 :
FL(猪)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
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http://www.scbt.com/zh/
800-820-8626
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