产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
HSC 70(B-6)抗体
目录 :
sc-7298
规格 :
200微克/毫升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
B-6
反应物种 :
人类, 小鼠, 大鼠, pigs
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, EMSA, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 176
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 1c, 2c, 5c
  • 免疫印迹; 小鼠; 图 6d
Xu X, Sun Y, Cen X, Shan B, Zhao Q, Xie T, et al. Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model. Protein Cell. 2021;: pubmed 出版商
  • 免疫印迹; 人类; 图 2c
Kemper M, Schiecke A, Maar H, Nikulin S, Poloznikov A, Galatenko V, et al. Integrin alpha-V is an important driver in pancreatic adenocarcinoma progression. J Exp Clin Cancer Res. 2021;40:214 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 6i
Silva Pinheiro P, Pardo Hernández C, Reyes A, Tilokani L, Mishra A, Cerutti R, et al. DNA polymerase gamma mutations that impair holoenzyme stability cause catalytic subunit depletion. Nucleic Acids Res. 2021;49:5230-5248 pubmed 出版商
  • 免疫印迹; 人类; 图 2f
Dahou H, Minati M, Jacquemin P, Assi M. Genetic Inactivation of Peroxiredoxin-I Impairs the Growth of Human Pancreatic Cancer Cells. Antioxidants (Basel). 2021;10: pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s4a
Rushworth L, Harle V, Repiščák P, Clark W, Shaw R, Hall H, et al. In vivo CRISPR/Cas9 knockout screen: TCEAL1 silencing enhances docetaxel efficacy in prostate cancer. Life Sci Alliance. 2020;3: pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
Lechertier T, Reynolds L, Kim H, Pedrosa A, Gómez Escudero J, Muñoz Félix J, et al. Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth. Nat Commun. 2020;11:2810 pubmed 出版商
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Somerville T, Biffi G, Da ler Plenker J, Hur S, He X, Vance K, et al. Squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation. elife. 2020;9: pubmed 出版商
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Onn L, Portillo M, Ilic S, Cleitman G, Stein D, Kaluski S, et al. SIRT6 is a DNA double-strand break sensor. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 1i
Nowialis P, Lopušná K, Opavska J, Haney S, Abraham A, Sheng P, et al. Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions. Nat Commun. 2019;10:4374 pubmed 出版商
  • 免疫细胞化学; 人类; 图 4a
Rhee H, Shaib A, Rehbach K, Lee C, Seif P, Thomas C, et al. An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons. Cell Rep. 2019;27:2212-2228.e7 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Kim J, He X, Liu J, Duan Z, Kim T, Gerard J, et al. Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression. J Biol Chem. 2019;294:8760-8772 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Rademaker G, Hennequière V, Brohée L, Nokin M, Lovinfosse P, Durieux F, et al. Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness. Oncogene. 2018;37:4398-4412 pubmed 出版商
  • 免疫沉淀; 人类; 图 6b
Liu L, An D, Xu J, Shao B, Li X, Shi J. Ac2-26 Induces IKKβ Degradation Through Chaperone-Mediated Autophagy Via HSPB1 in NCM-Treated Microglia. Front Mol Neurosci. 2018;11:76 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1a
Le Duff M, Gouju J, Jonchère B, Guillon J, Toutain B, Boissard A, et al. Regulation of senescence escape by the cdk4-EZH2-AP2M1 pathway in response to chemotherapy. Cell Death Dis. 2018;9:199 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2i
Wan Y, Wang L, Zhu C, Zheng Q, Wang G, Tong J, et al. Aptamer-Conjugated Extracellular Nanovesicles for Targeted Drug Delivery. Cancer Res. 2018;78:798-808 pubmed 出版商
  • 免疫印迹; 大鼠; ; 图 4a
Pannérec A, Migliavacca E, de Castro A, Michaud J, Karaz S, Goulet L, et al. Vitamin B12 deficiency and impaired expression of amnionless during aging. J Cachexia Sarcopenia Muscle. 2018;9:41-52 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3d
Zhao T, Hong Y, Yin P, Li S, Li X. Differential HspBP1 expression accounts for the greater vulnerability of neurons than astrocytes to misfolded proteins. Proc Natl Acad Sci U S A. 2017;114:E7803-E7811 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
  • 免疫印迹; 小鼠; 图 1b
Groves J, Zachara N. Characterization of tools to detect and enrich human and mouse O-GlcNAcase. Glycobiology. 2017;: pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Sarper M, Allen M, Gomm J, Haywood L, Decock J, Thirkettle S, et al. Loss of MMP-8 in ductal carcinoma in situ (DCIS)-associated myoepithelial cells contributes to tumour promotion through altered adhesive and proteolytic function. Breast Cancer Res. 2017;19:33 pubmed 出版商
  • 免疫印迹; 大鼠; 图 2a
Hardonnière K, Fernier M, Gallais I, Mograbi B, Podechard N, Le Ferrec E, et al. Role for the ATPase inhibitory factor 1 in the environmental carcinogen-induced Warburg phenotype. Sci Rep. 2017;7:195 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 5d
Reynolds L, D Amico G, Lechertier T, Papachristodoulou A, Muñoz Félix J, De Arcangelis A, et al. Dual role of pericyte ?6?1-integrin in tumour blood vessels. J Cell Sci. 2017;130:1583-1595 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 s7a
Lee J, Hsu C, Michael M, Nanda A, Liu L, McMillan J, et al. Large Intragenic Deletion in DSTYK Underlies Autosomal-Recessive Complicated Spastic Paraparesis, SPG23. Am J Hum Genet. 2017;100:364-370 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1b
Mukhopadhyay C, Triplett A, Bargar T, HECKMAN C, Wagner K, Naramura M. Casitas B-cell lymphoma (Cbl) proteins protect mammary epithelial cells from proteotoxicity of active c-Src accumulation. Proc Natl Acad Sci U S A. 2016;113:E8228-E8237 pubmed 出版商
  • 免疫印迹; 人类; 图 s2
Blomme A, Fahmy K, Peulen O, Costanza B, Fontaine M, Struman I, et al. Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes. Oncotarget. 2016;7:83669-83683 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7b
Swartz K, Wood S, Murthy T, Ramirez O, Qin G, Pillai M, et al. E2F-2 Promotes Nuclear Condensation and Enucleation of Terminally Differentiated Erythroblasts. Mol Cell Biol. 2017;37: pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 6a
Parrales A, Ranjan A, Iyer S, Padhye S, Weir S, Roy A, et al. DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway. Nat Cell Biol. 2016;18:1233-1243 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000; 图 6c
Frentzas S, Simoneau E, Bridgeman V, Vermeulen P, Foo S, Kostaras E, et al. Vessel co-option mediates resistance to anti-angiogenic therapy in liver metastases. Nat Med. 2016;22:1294-1302 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Jin Q, Ren Y, Wang M, Suraneni P, Li D, Crispino J, et al. Novel function of FAXDC2 in megakaryopoiesis. Blood Cancer J. 2016;6:e478 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2d
Schiera G, Di Liegro C, Puleo V, Colletta O, Fricano A, Cancemi P, et al. Extracellular vesicles shed by melanoma cells contain a modified form of H1.0 linker histone and H1.0 mRNA-binding proteins. Int J Oncol. 2016;49:1807-1814 pubmed 出版商
  • 免疫印迹; 人类; 图 7a
Sayyed K, Vee M, Abdel Razzak Z, Jouan E, Stieger B, Denizot C, et al. Alteration of human hepatic drug transporter activity and expression by cigarette smoke condensate. Toxicology. 2016;363-364:58-71 pubmed 出版商
  • 免疫印迹; 人类; 图 4B
Yang W, Ng F, Chan K, Pu X, Poston R, Ren M, et al. Coronary-Heart-Disease-Associated Genetic Variant at the COL4A1/COL4A2 Locus Affects COL4A1/COL4A2 Expression, Vascular Cell Survival, Atherosclerotic Plaque Stability and Risk of Myocardial Infarction. PLoS Genet. 2016;12:e1006127 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Roychowdhury S, McCullough R, Sanz Garcia C, Saikia P, Alkhouri N, Matloob A, et al. Receptor interacting protein 3 protects mice from high-fat diet-induced liver injury. Hepatology. 2016;64:1518-1533 pubmed 出版商
  • 免疫印迹; 小鼠; 1:6000; 图 2C
Chen L, DeWispelaere A, Dastvan F, Osborne W, Blechner C, Windhorst S, et al. Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity. PLoS ONE. 2016;11:e0155726 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 3
Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, et al. Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep. 2016;17:953-64 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Rider M, Hurwitz S, Meckes D. ExtraPEG: A Polyethylene Glycol-Based Method for Enrichment of Extracellular Vesicles. Sci Rep. 2016;6:23978 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Derangère V, Fumet J, Boidot R, Bengrine L, Limagne E, Chevriaux A, et al. Does bevacizumab impact anti-EGFR therapy efficacy in metastatic colorectal cancer?. Oncotarget. 2016;7:9309-21 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Zhao B, Tan T, Mei Y, Yang J, Yu Y, Verma A, et al. H2AX deficiency is associated with erythroid dysplasia and compromised haematopoietic stem cell function. Sci Rep. 2016;6:19589 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Cousin F, Jouan Lanhouet S, Théret N, Brenner C, Jouan E, Le Moigne Muller G, et al. The probiotic Propionibacterium freudenreichii as a new adjuvant for TRAIL-based therapy in colorectal cancer. Oncotarget. 2016;7:7161-78 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 2
Xie C, Ginet V, Sun Y, Koike M, Zhou K, Li T, et al. Neuroprotection by selective neuronal deletion of Atg7 in neonatal brain injury. Autophagy. 2016;12:410-23 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Wen Q, Yang Q, Goldenson B, Malinge S, Lasho T, Schneider R, et al. Targeting megakaryocytic-induced fibrosis in myeloproliferative neoplasms by AURKA inhibition. Nat Med. 2015;21:1473-80 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Vétillard A, Jonchère B, Moreau M, Toutain B, Henry C, Fontanel S, et al. Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis. Oncotarget. 2015;6:43342-62 pubmed 出版商
  • 免疫印迹; 人类; 1:30000; 图 2
Maris P, Blomme A, Palacios A, Costanza B, Bellahcène A, Bianchi E, et al. Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer. PLoS Med. 2015;12:e1001871 pubmed 出版商
  • 免疫印迹; pigs ; 图 2
Georgiannakis A, Burgoyne T, Lueck K, Futter C, Greenwood J, Moss S. Retinal Pigment Epithelial Cells Mitigate the Effects of Complement Attack by Endocytosis of C5b-9. J Immunol. 2015;195:3382-9 pubmed 出版商
  • 免疫印迹; 小鼠
Noritake K, Aki T, Funakoshi T, Unuma K, Uemura K. Direct Exposure to Ethanol Disrupts Junctional Cell-Cell Contact and Hippo-YAP Signaling in HL-1 Murine Atrial Cardiomyocytes. PLoS ONE. 2015;10:e0136952 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Conigliaro A, Costa V, Lo Dico A, Saieva L, Buccheri S, Dieli F, et al. CD90+ liver cancer cells modulate endothelial cell phenotype through the release of exosomes containing H19 lncRNA. Mol Cancer. 2015;14:155 pubmed 出版商
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Hofmann B, Schlüter L, Lange P, Mercanoglu B, Ewald F, Fölster A, et al. COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer. Mol Cancer. 2015;14:109 pubmed 出版商
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Alexandrova E, Yallowitz A, Li D, Xu S, Schulz R, Proia D, et al. Improving survival by exploiting tumour dependence on stabilized mutant p53 for treatment. Nature. 2015;523:352-6 pubmed 出版商
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Saini P, Li Y, Dobbelstein M. Wee1 is required to sustain ATR/Chk1 signaling upon replicative stress. Oncotarget. 2015;6:13072-87 pubmed
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Decock J, Hendrickx W, Thirkettle S, Gutiérrez Fernández A, Robinson S, Edwards D. Pleiotropic functions of the tumor- and metastasis-suppressing matrix metalloproteinase-8 in mammary cancer in MMTV-PyMT transgenic mice. Breast Cancer Res. 2015;17:38 pubmed 出版商
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Grabner B, Schramek D, Mueller K, Moll H, Svinka J, Hoffmann T, et al. Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis. Nat Commun. 2015;6:6285 pubmed 出版商
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Kramer D, Schön M, Bayerlová M, Bleckmann A, Schön M, Zörnig M, et al. A pro-apoptotic function of iASPP by stabilizing p300 and CBP through inhibition of BRMS1 E3 ubiquitin ligase activity. Cell Death Dis. 2015;6:e1634 pubmed 出版商
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Morlé A, Garrido C, Micheau O. Hyperthermia restores apoptosis induced by death receptors through aggregation-induced c-FLIP cytosolic depletion. Cell Death Dis. 2015;6:e1633 pubmed 出版商
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Bele A, Mirza S, Zhang Y, Ahmad Mir R, Lin S, Kim J, et al. The cell cycle regulator ecdysoneless cooperates with H-Ras to promote oncogenic transformation of human mammary epithelial cells. Cell Cycle. 2015;14:990-1000 pubmed 出版商
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  • 免疫印迹; 人类
Chen Y, Schnetz M, Irarrazabal C, Shen R, Williams C, Burg M, et al. Proteomic identification of proteins associated with the osmoregulatory transcription factor TonEBP/OREBP: functional effects of Hsp90 and PARP-1. Am J Physiol Renal Physiol. 2007;292:F981-92 pubmed
Dinić M, Herholz M, Kačarević U, Radojević D, Novovic K, Đokić J, et al. Host-commensal interaction promotes health and lifespan in Caenorhabditis elegans through the activation of HLH-30/TFEB-mediated autophagy. Aging (Albany NY). 2021;13:8040-8054 pubmed 出版商
Lees D, Reynolds L, Pedrosa A, Roy Luzarraga M, Hodivala Dilke K. Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression. Angiogenesis. 2021;24:471-482 pubmed 出版商
Chen J, Yang Y, Russu W, Chan W. The Aryl Hydrocarbon Receptor Undergoes Chaperone-Mediated Autophagy in Triple-Negative Breast Cancer Cells. Int J Mol Sci. 2021;22: pubmed 出版商
Saini H, Sharma H, Mukherjee S, Chowdhury S, Chowdhury R. Verteporfin disrupts multiple steps of autophagy and regulates p53 to sensitize osteosarcoma cells. Cancer Cell Int. 2021;21:52 pubmed 出版商
Huh D, Passarelli M, Gao J, Dusmatova S, Goin C, Fish L, et al. A stress-induced tyrosine-tRNA depletion response mediates codon-based translational repression and growth suppression. EMBO J. 2021;40:e106696 pubmed 出版商
Abokyi S, Shan S, To C, Chan H, Tse D. Autophagy Upregulation by the TFEB Inducer Trehalose Protects against Oxidative Damage and Cell Death Associated with NRF2 Inhibition in Human RPE Cells. Oxid Med Cell Longev. 2020;2020:5296341 pubmed 出版商
Anania S, Peiffer R, Rademaker G, Hego A, Thiry M, Deldicque L, et al. Myoferlin Is a Yet Unknown Interactor of the Mitochondrial Dynamics' Machinery in Pancreas Cancer Cells. Cancers (Basel). 2020;12: pubmed 出版商
Kouloulia S, Hallin E, Simbriger K, Amorim I, Lach G, Amvrosiadis T, et al. Raptor-Mediated Proteasomal Degradation of Deamidated 4E-BP2 Regulates Postnatal Neuronal Translation and NF-κB Activity. Cell Rep. 2019;29:3620-3635.e7 pubmed 出版商
Ni Y, Schmidt K, Werner B, Koenig J, Guldner I, Schnepp P, et al. Death effector domain-containing protein induces vulnerability to cell cycle inhibition in triple-negative breast cancer. Nat Commun. 2019;10:2860 pubmed 出版商
de Araujo E, Erdogan F, Neubauer H, Meneksedag Erol D, Manaswiyoungkul P, Eram M, et al. Structural and functional consequences of the STAT5BN642H driver mutation. Nat Commun. 2019;10:2517 pubmed 出版商
Fang C, Kuo H, Hsu S, Yih L. HSP70 is required for the proper assembly of pericentriolar material and function of mitotic centrosomes. Cell Div. 2019;14:4 pubmed 出版商
Guillon J, Petit C, Moreau M, Toutain B, Henry C, Roche H, et al. Regulation of senescence escape by TSP1 and CD47 following chemotherapy treatment. Cell Death Dis. 2019;10:199 pubmed 出版商
Greer Y, Gilbert S, Gril B, Narwal R, Peacock Brooks D, Tice D, et al. MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgrowth of metastatic triple-negative breast cancer. Breast Cancer Res. 2019;21:27 pubmed 出版商
Kari V, Raul S, Henck J, Kitz J, Kramer F, Kosinsky R, et al. The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness. Clin Epigenetics. 2019;11:4 pubmed 出版商
Ni Y, Zhou N, Xue W, Rong L, Yung W, Lin R, et al. A new role of anterograde motor Kif5b in facilitating large clathrin-coated vesicle mediated endocytosis via regulating clathrin uncoating. Cell Discov. 2018;4:65 pubmed 出版商
Somerville T, Xu Y, Miyabayashi K, Tiriac H, Cleary C, Maia Silva D, et al. TP63-Mediated Enhancer Reprogramming Drives the Squamous Subtype of Pancreatic Ductal Adenocarcinoma. Cell Rep. 2018;25:1741-1755.e7 pubmed 出版商
Niu X, Su L, Qi S, Gao Z, Zhang Q, Zhang S. GRP75 modulates oncogenic Dbl-driven endocytosis derailed via the CHIP-mediated ubiquitin degradation pathway. Cell Death Dis. 2018;9:971 pubmed 出版商
Lopez Charcas O, Espinosa A, Alfaro A, Herrera Carrillo Z, Ramírez Cordero B, Cortes Reynosa P, et al. The invasiveness of human cervical cancer associated to the function of NaV1.6 channels is mediated by MMP-2 activity. Sci Rep. 2018;8:12995 pubmed 出版商
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产品信息
产品名称 :
HSC 70(B-6)抗体
基因名称 :
HSPA8
规格 :
200微克/毫升
目录号 :
sc-7298
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
HSC 70
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), FCM, 酶联免疫吸附测定
表位 :
C末端(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
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http://www.scbt.com/zh/
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