产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
p-ERK(E-4)抗体
目录 :
sc-7383
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
E-4
反应物种 :
番茄, kangaroo rats, 人类, 小鼠, 大鼠, ,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-自由浮动切片
更多信息或购买 :
文章摘录数: 682
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 8a
Chen S, Yun F, Yao Y, Cao M, Zhang Y, Wang J, et al. USP38 critically promotes asthmatic pathogenesis by stabilizing JunB protein. J Exp Med. 2018;215:2850-2867 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4d
Li F, Li Y, Liang H, Xu T, Kong Y, Huang M, et al. HECTD3 mediates TRAF3 polyubiquitination and type I interferon induction during bacterial infection. J Clin Invest. 2018;128:4148-4162 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Li R, Sahu S, Schachner M. Phenelzine, a small organic compound mimicking the functions of cell adhesion molecule L1, promotes functional recovery after mouse spinal cord injury. Restor Neurol Neurosci. 2018;36:469-483 pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Lei F, Jin L, Liu X, Lai F, Yan X, Farrelly M, et al. RIP1 protects melanoma cells from apoptosis induced by BRAF/MEK inhibitors. Cell Death Dis. 2018;9:679 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Xue Z, Vis D, Bruna A, Sustic T, van Wageningen S, Batra A, et al. MAP3K1 and MAP2K4 mutations are associated with sensitivity to MEK inhibitors in multiple cancer models. Cell Res. 2018;28:719-729 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6d
Huang M, Qi W, Fang S, Jiang P, Yang C, Mo Y, et al. Pigment Epithelium-Derived Factor Plays a Role in Alzheimer's Disease by Negatively Regulating Aβ42. Neurotherapeutics. 2018;15:728-741 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Qian Z, Ryu B, Kang K, Heo S, Kang D, Bae S, et al. Cellular properties of the fermented microalgae Pavlova lutheri and its isolated active peptide in osteoblastic differentiation of MG?63 cells. Mol Med Rep. 2018;17:2044-2050 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Cho M, Lee J, Shin M, Kim H, Choi Y, Rho S, et al. TSC-22 inhibits CSF-1R function and induces apoptosis in cervical cancer. Oncotarget. 2017;8:97990-98003 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3g
Ma S, Wan X, Deng Z, Shi L, Hao C, Zhou Z, et al. Epigenetic regulator CXXC5 recruits DNA demethylase Tet2 to regulate TLR7/9-elicited IFN response in pDCs. J Exp Med. 2017;214:1471-1491 pubmed 出版商
  • 免疫印迹; 人类; 图 3e
Gaggianesi M, Turdo A, Chinnici A, Lipari E, Apuzzo T, Benfante A, et al. IL4 Primes the Dynamics of Breast Cancer Progression via DUSP4 Inhibition. Cancer Res. 2017;77:3268-3279 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3c
Mon N, Senga T, Ito S. Interleukin-1? activates focal adhesion kinase and Src to induce matrix metalloproteinase-9 production and invasion of MCF-7 breast cancer cells. Oncol Lett. 2017;13:955-960 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4b
Schweighoffer E, Nys J, Vanes L, Smithers N, Tybulewicz V. TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK. J Exp Med. 2017;214:1269-1280 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Yang K, Chen Y, To K, Wang F, Li D, Chen L, et al. Alectinib (CH5424802) antagonizes ABCB1- and ABCG2-mediated multidrug resistance in vitro, in vivo and ex vivo. Exp Mol Med. 2017;49:e303 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
de Oliveira R, de Campos Castilho G, da Cunha A, Miyajima F, de Oliveira Martins D. Dilodendron bipinnatum Radlk. inhibits pro-inflammatory mediators through the induction of MKP-1 and the down-regulation of MAPKp38/JNK/NF-?B pathways and COX-2 in LPS-activated RAW 264.7 cells. J Ethnopharmacol. 2017;202:127-137 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 2b
Carpi S, Fogli S, Polini B, Montagnani V, Podestà A, Breschi M, et al. Tumor-promoting effects of cannabinoid receptor type 1 in human melanoma cells. Toxicol In Vitro. 2017;40:272-279 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 2b
Difranco K, Mulligan J, Sumal A, Diamond G. Induction of CFTR gene expression by 1,25(OH)2 vitamin D3, 25OH vitamin D3, and vitamin D3 in cultured human airway epithelial cells and in mouse airways. J Steroid Biochem Mol Biol. 2017;173:323-332 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 2e
Xu X, Fan Z, Liang C, Li L, Wang L, Liang Y, et al. A signature motif in LIM proteins mediates binding to checkpoint proteins and increases tumour radiosensitivity. Nat Commun. 2017;8:14059 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Babagana M, Johnson S, Slabodkin H, Bshara W, Morrison C, Kandel E. P21-activated kinase 1 regulates resistance to BRAF inhibition in human cancer cells. Mol Carcinog. 2017;56:1515-1525 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Jung J, Jung H, Neupane S, Kim K, Kim J, Yamamoto H, et al. Involvement of PI3K and PKA pathways in mouse tongue epithelial differentiation. Acta Histochem. 2017;119:92-98 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Gross S, Devraj K, Feng Y, Macas J, Liebner S, Wieland T. Nucleoside diphosphate kinase B regulates angiogenic responses in the endothelium via caveolae formation and c-Src-mediated caveolin-1 phosphorylation. J Cereb Blood Flow Metab. 2017;37:2471-2484 pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Che D, Zhou T, Lan Y, Xie J, Gong H, Li C, et al. High glucose-induced epithelial-mesenchymal transition contributes to the upregulation of fibrogenic factors in retinal pigment epithelial cells. Int J Mol Med. 2016;38:1815-1822 pubmed 出版商
  • 免疫印迹; 大鼠; 图 6b
Belliard A, Gulati G, Duan Q, Alves R, Brewer S, Madan N, et al. Ischemia/reperfusion-induced alterations of enzymatic and signaling functions of the rat cardiac Na+/K+-ATPase: protection by ouabain preconditioning. Physiol Rep. 2016;4: pubmed
  • 免疫印迹; 人类; 1:1500; 图 4a
Zhong W, Wang X, Pan B, Li F, Kuang L, Su Z. Eupatilin induces human renal cancer cell apoptosis via ROS-mediated MAPK and PI3K/AKT signaling pathways. Oncol Lett. 2016;12:2894-2899 pubmed
  • 免疫印迹; 小鼠; 图 3
Jin Q, Ren Y, Wang M, Suraneni P, Li D, Crispino J, et al. Novel function of FAXDC2 in megakaryopoiesis. Blood Cancer J. 2016;6:e478 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 表 1
Jansson D, Scotter E, Rustenhoven J, Coppieters N, Smyth L, Oldfield R, et al. Interferon-? blocks signalling through PDGFR? in human brain pericytes. J Neuroinflammation. 2016;13:249 pubmed
  • 免疫印迹; 人类; 图 6e
Egholm C, Khammy M, Dalsgaard T, Mazur A, Tritsaris K, Hansen A, et al. GLP-1 inhibits VEGFA-mediated signaling in isolated human endothelial cells and VEGFA-induced dilation of rat mesenteric arteries. Am J Physiol Heart Circ Physiol. 2016;311:H1214-H1224 pubmed 出版商
  • 免疫印迹; 人类; 图 4b
Torres A, Vargas Y, Uribe D, Jaramillo C, Gleisner A, Salazar Onfray F, et al. Adenosine A3 receptor elicits chemoresistance mediated by multiple resistance-associated protein-1 in human glioblastoma stem-like cells. Oncotarget. 2016;7:67373-67386 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Yadav V, Hong K, Zeldin D, Nayeem M. Vascular endothelial over-expression of soluble epoxide hydrolase (Tie2-sEH) enhances adenosine A1 receptor-dependent contraction in mouse mesenteric arteries: role of ATP-sensitive K+ channels. Mol Cell Biochem. 2016;422:197-206 pubmed
  • 免疫印迹; 小鼠; 图 7a
Wu Y, Ren D, Chen G. Siglec-E Negatively Regulates the Activation of TLR4 by Controlling Its Endocytosis. J Immunol. 2016;197:3336-3347 pubmed
  • 免疫印迹; 人类; 图 4
Wang H, Han X, Bretz C, Becker S, Gambhir D, Smith G, et al. Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization. Mol Ther Methods Clin Dev. 2016;3:16056 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Kupka S, De Miguel D, Dráber P, Martino L, Surinova S, Rittinger K, et al. SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes. Cell Rep. 2016;16:2271-80 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 2
Jiang Q, Chen S, Hu C, Huang P, Shen H, Zhao W. Neuregulin-1 (Nrg1) signaling has a preventive role and is altered in the frontal cortex under the pathological conditions of Alzheimer's disease. Mol Med Rep. 2016;14:2614-24 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2
Di Siena S, Gimmelli R, Nori S, Barbagallo F, Campolo F, Dolci S, et al. Activated c-Kit receptor in the heart promotes cardiac repair and regeneration after injury. Cell Death Dis. 2016;7:e2317 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Shi K, Qian J, Qi L, Mao D, Chen Y, Zhu Y, et al. Atorvastatin antagonizes the visfatin-induced expression of inflammatory mediators via the upregulation of NF-?B activation in HCAECs. Oncol Lett. 2016;12:1438-1444 pubmed
  • 免疫印迹; 小鼠; 图 2a
Inda C, Dos Santos Claro P, Bonfiglio J, Senin S, Maccarrone G, Turck C, et al. Different cAMP sources are critically involved in G protein-coupled receptor CRHR1 signaling. J Cell Biol. 2016;214:181-95 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Wang C, Guo S, Wang J, Yan X, Farrelly M, Zhang Y, et al. Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922. Oncotarget. 2016;7:49597-49610 pubmed 出版商
  • 免疫印迹; 人类; 图 3h
Elzi D, Song M, Blackman B, Weintraub S, Lopez Terrada D, Chen Y, et al. FGF19 functions as autocrine growth factor for hepatoblastoma. Genes Cancer. 2016;7:125-35 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 5d
Tisza M, Zhao W, Fuentes J, Prijic S, Chen X, Levental I, et al. Motility and stem cell properties induced by the epithelial-mesenchymal transition require destabilization of lipid rafts. Oncotarget. 2016;7:51553-51568 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4
Yang Z, Jiang Q, Chen S, Hu C, Shen H, Huang P, et al. Differential changes in Neuregulin-1 signaling in major brain regions in a lipopolysaccharide-induced neuroinflammation mouse model. Mol Med Rep. 2016;14:790-6 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500; 图 5a
Zhang C, Li L, Zhao B, Jiao A, Li X, Sun N, et al. Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling. Int J Endocrinol. 2016;2016:4513051 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7c
Wu Y, Lan C, Ren D, Chen G. Induction of Siglec-1 by Endotoxin Tolerance Suppresses the Innate Immune Response by Promoting TGF-?1 Production. J Biol Chem. 2016;291:12370-82 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Choi H, Kim M, Choi Y, Shin Y, Cho S, Ko S. Rhus verniciflua Stokes (RVS) and butein induce apoptosis of paclitaxel-resistant SKOV-3/PAX ovarian cancer cells through inhibition of AKT phosphorylation. BMC Complement Altern Med. 2016;16:122 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2
Kim S, Choi K, Cho S, Yun S, Jeon J, Koh Y, et al. Fisetin stimulates autophagic degradation of phosphorylated tau via the activation of TFEB and Nrf2 transcription factors. Sci Rep. 2016;6:24933 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Alemán O, Mora N, Cortés Vieyra R, Uribe Querol E, Rosales C. Differential Use of Human Neutrophil Fc? Receptors for Inducing Neutrophil Extracellular Trap Formation. J Immunol Res. 2016;2016:2908034 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Huang J, Yao C, Chuang S, Yeh C, Lee L, Chen R, et al. Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/STAT signaling pathway suppression and apoptosis induction. BMC Cancer. 2016;16:245 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Relic B, Charlier E, Deroyer C, Malaise O, Neuville S, Desoroux A, et al. BAY 11-7085 induces glucocorticoid receptor activation and autophagy that collaborate with apoptosis to induce human synovial fibroblast cell death. Oncotarget. 2016;7:23370-82 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Lee J, Kim H, Rho S, Lee S. eIF3f reduces tumor growth by directly interrupting clusterin with anti-apoptotic property in cancer cells. Oncotarget. 2016;7:18541-57 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:50; 图 5
  • 免疫组化; 小鼠; 1:50; 图 5
Yang H, Vainshtein A, Maik Rachline G, Peles E. G protein-coupled receptor 37 is a negative regulator of oligodendrocyte differentiation and myelination. Nat Commun. 2016;7:10884 pubmed 出版商
  • 免疫印迹; 人类; 图 3c
Atiq R, Hertz R, Eldad S, Smeir E, Bar Tana J. Suppression of B-Raf(V600E) cancers by MAPK hyper-activation. Oncotarget. 2016;7:18694-704 pubmed 出版商
  • 免疫印迹; 人类; 图 8
  • 免疫印迹; 小鼠; 图 5
Hu H, Wang H, Xiao Y, Jin J, Chang J, Zou Q, et al. Otud7b facilitates T cell activation and inflammatory responses by regulating Zap70 ubiquitination. J Exp Med. 2016;213:399-414 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7e
Chen Y, Zheng Y, You X, Yu M, Fu G, Su X, et al. Kras Is Critical for B Cell Lymphopoiesis. J Immunol. 2016;196:1678-85 pubmed 出版商
  • 免疫组化; 小鼠; 图 7
  • 免疫印迹; 大鼠; 图 1d
Peng K, Tian X, Qian Y, Skibba M, Zou C, Liu Z, et al. Novel EGFR inhibitors attenuate cardiac hypertrophy induced by angiotensin II. J Cell Mol Med. 2016;20:482-94 pubmed 出版商
  • 酶联免疫吸附测定; 人类; 1:500; 图 10
Daniele S, Barresi E, Zappelli E, Marinelli L, Novellino E, Da Settimo F, et al. Long lasting MDM2/Translocator protein modulator: a new strategy for irreversible apoptosis of human glioblastoma cells. Oncotarget. 2016;7:7866-84 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Pivonello C, Negri M, De Martino M, Napolitano M, De Angelis C, Provvisiero D, et al. The dual targeting of insulin and insulin-like growth factor 1 receptor enhances the mTOR inhibitor-mediated antitumor efficacy in hepatocellular carcinoma. Oncotarget. 2016;7:9718-31 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500; 图 6
Lin C, Wang C, Hsu S, Liao L, Lin T, Hsueh C. Molecular Mechanisms Responsible for Neuron-Derived Conditioned Medium (NCM)-Mediated Protection of Ischemic Brain. PLoS ONE. 2016;11:e0146692 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Sun J, Fu X, Liu Y, Wang Y, Huo B, Guo Y, et al. Hypoglycemic effect and mechanism of honokiol on type 2 diabetic mice. Drug Des Devel Ther. 2015;9:6327-42 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 10
Daniele S, Zappelli E, Martini C. Trazodone regulates neurotrophic/growth factors, mitogen-activated protein kinases and lactate release in human primary astrocytes. J Neuroinflammation. 2015;12:225 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 s7
  • 免疫印迹; 小鼠; 1:1000; 图 2
  • 免疫印迹; 人类; 1:1000; 图 2
Bunda S, Burrell K, Heir P, Zeng L, Alamsahebpour A, Kano Y, et al. Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis. Nat Commun. 2015;6:8859 pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Lim J, Nguyen K, Han J, Jang I, Fabian C, Cho K. Direct Regulation of TLR5 Expression by Caveolin-1. Mol Cells. 2015;38:1111-7 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Giri K, Pabelick C, Mukherjee P, Prakash Y. Hepatoma derived growth factor (HDGF) dynamics in ovarian cancer cells. Apoptosis. 2016;21:329-39 pubmed 出版商
  • 免疫印迹; 人类; 图 S3
Wang Z, Ma B, Li H, Xiao X, Zhou W, Liu F, et al. Protein 4.1N acts as a potential tumor suppressor linking PP1 to JNK-c-Jun pathway regulation in NSCLC. Oncotarget. 2016;7:509-23 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Yen Y, Hsiao J, Jiang S, Chang J, Wang S, Shen Y, et al. Insulin-like growth factor-independent insulin-like growth factor binding protein 3 promotes cell migration and lymph node metastasis of oral squamous cell carcinoma cells by requirement of integrin β1. Oncotarget. 2015;6:41837-55 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s3
Vernot J, Perdomo Arciniegas A, Pérez Quintero L, Martínez D. Modulating p56Lck in T-Cells by a Chimeric Peptide Comprising Two Functionally Different Motifs of Tip from Herpesvirus saimiri. J Immunol Res. 2015;2015:395371 pubmed 出版商
  • 免疫印迹; 人类; 图 8
Wu S, Guo Z, Hopkins C, Wei N, Chu E, Wipf P, et al. Bis-cyclopropane analog of disorazole C1 is a microtubule-destabilizing agent active in ABCB1-overexpressing human colon cancer cells. Oncotarget. 2015;6:40866-79 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Barbáchano A, Fernández Barral A, Pereira F, Segura M, Ordóñez Morán P, Carrillo de Santa Pau E, et al. SPROUTY-2 represses the epithelial phenotype of colon carcinoma cells via upregulation of ZEB1 mediated by ETS1 and miR-200/miR-150. Oncogene. 2016;35:2991-3003 pubmed 出版商
  • 免疫印迹; 人类
Kim H, Lim J, Kim J, Kim Y, Park S, Sohn J. Panaxydol, a component of Panax ginseng, induces apoptosis in cancer cells through EGFR activation and ER stress and inhibits tumor growth in mouse models. Int J Cancer. 2016;138:1432-41 pubmed 出版商
  • 免疫印迹; 人类; 图 3c
Xing R, Li L, Chen L, Gao Z, Wang H, Li W, et al. Copy number variations of HLA-I and activation of NKp30 pathway determine the sensitivity of gastric cancer cells to the cytotoxicity of natural killer cells. Oncogene. 2016;35:2584-91 pubmed 出版商
  • 免疫印迹; 猪; 图 2
Georgiannakis A, Burgoyne T, Lueck K, Futter C, Greenwood J, Moss S. Retinal Pigment Epithelial Cells Mitigate the Effects of Complement Attack by Endocytosis of C5b-9. J Immunol. 2015;195:3382-9 pubmed 出版商
  • 免疫印迹; 人类
Wong T, Lin S, Leung L. The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic Cells. PLoS ONE. 2015;10:e0135637 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
Zhao C, Su Y, Zhang J, Feng Q, Qu L, Wang L, et al. Fibrinogen-derived fibrinostatin inhibits tumor growth through anti-angiogenesis. Cancer Sci. 2015;106:1596-606 pubmed 出版商
  • 免疫印迹; 人类
Sivaraj K, Li R, Albarrán Juárez J, Wang S, Tischner D, Grimm M, et al. Endothelial Gαq/11 is required for VEGF-induced vascular permeability and angiogenesis. Cardiovasc Res. 2015;108:171-80 pubmed 出版商
  • 免疫印迹; 人类
Wu M, Lee W, Hua K, Kuo M, Lin M. Macrophage Infiltration Induces Gastric Cancer Invasiveness by Activating the β-Catenin Pathway. PLoS ONE. 2015;10:e0134122 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6b
Zou Q, Jin J, Xiao Y, Hu H, Zhou X, Jie Z, et al. T cell development involves TRAF3IP3-mediated ERK signaling in the Golgi. J Exp Med. 2015;212:1323-36 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
García Pérez D, Laorden M, Milanés M. Regulation of Pleiotrophin, Midkine, Receptor Protein Tyrosine Phosphatase β/ζ, and Their Intracellular Signaling Cascades in the Nucleus Accumbens During Opiate Administration. Int J Neuropsychopharmacol. 2015;19: pubmed 出版商
  • 免疫组化-自由浮动切片; 大鼠
Gorojod R, Alaimo A, Porte Alcon S, Pomilio C, Saravia F, Kotler M. The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions. Free Radic Biol Med. 2015;87:237-51 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Seo G, Ho M, Bui N, Kim Y, Koh D, Lim Y, et al. Novel naphthochalcone derivative accelerate dermal wound healing through induction of epithelial-mesenchymal transition of keratinocyte. J Biomed Sci. 2015;22:47 pubmed 出版商
  • 免疫印迹; 小鼠
He L, Zang A, Du M, Ma D, Yuan C, Zhou C, et al. mTOR regulates TLR-induced c-fos and Th1 responses to HBV and HCV vaccines. Virol Sin. 2015;30:174-89 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Roda D, Castillo J, Telechea Fernández M, Gil A, López Rodas G, Franco L, et al. EGF-Induced Acetylation of Heterogeneous Nuclear Ribonucleoproteins Is Dependent on KRAS Mutational Status in Colorectal Cancer Cells. PLoS ONE. 2015;10:e0130543 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6
Pickard A, McDade S, McFarland M, McCluggage W, Wheeler C, McCance D. HPV16 Down-Regulates the Insulin-Like Growth Factor Binding Protein 2 to Promote Epithelial Invasion in Organotypic Cultures. PLoS Pathog. 2015;11:e1004988 pubmed 出版商
  • 免疫印迹; 小鼠
Choi J, Kim J, Kim T, Park J, Lee J, Kim H, et al. TRH and TRH receptor system in the basolateral amygdala mediate stress-induced depression-like behaviors. Neuropharmacology. 2015;97:346-56 pubmed 出版商
  • 免疫印迹; 人类
Faggi F, Codenotti S, Poliani P, Cominelli M, Chiarelli N, Colombi M, et al. MURC/cavin-4 Is Co-Expressed with Caveolin-3 in Rhabdomyosarcoma Tumors and Its Silencing Prevents Myogenic Differentiation in the Human Embryonal RD Cell Line. PLoS ONE. 2015;10:e0130287 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Gopinathan G, Milagre C, Pearce O, Reynolds L, Hodivala Dilke K, Leinster D, et al. Interleukin-6 Stimulates Defective Angiogenesis. Cancer Res. 2015;75:3098-107 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Li T, Lu H, Mukherjee D, Lahiri S, Shen C, Yu L, et al. Identification of epidermal growth factor receptor and its inhibitory microRNA141 as novel targets of Krüppel-like factor 8 in breast cancer. Oncotarget. 2015;6:21428-42 pubmed
  • 免疫印迹; 人类; 图 s8
Luan Q, Jin L, Jiang C, Tay K, Lai F, Liu X, et al. RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy. Autophagy. 2015;11:975-94 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Yen C, Chiang W, Liu S, Lin C, Liao K, Lin C, et al. Impacts of autophagy-inducing ingredient of areca nut on tumor cells. PLoS ONE. 2015;10:e0128011 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Reigada D, Nieto Díaz M, Navarro Ruiz R, Caballero López M, Del Águila A, Muñoz Galdeano T, et al. Acute administration of ucf-101 ameliorates the locomotor impairments induced by a traumatic spinal cord injury. Neuroscience. 2015;300:404-17 pubmed 出版商
  • 免疫印迹; 大鼠; 图 5
Li P, Sheu M, Ma W, Pan C, Sheu J, Wu C. Anti-Restenotic Roles of Dihydroaustrasulfone Alcohol Involved in Inhibiting PDGF-BB-Stimulated Proliferation and Migration of Vascular Smooth Muscle Cells. Mar Drugs. 2015;13:3046-60 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Wong T, Lin S, Leung L. The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68. Br J Nutr. 2015;113:1844-52 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500; 图 4g
Cong X, Zhang Y, Li J, Mei M, Ding C, Xiang R, et al. Claudin-4 is required for modulation of paracellular permeability by muscarinic acetylcholine receptor in epithelial cells. J Cell Sci. 2015;128:2271-86 pubmed 出版商
  • 免疫印迹; 人类
Pasqualon T, Pruessmeyer J, Weidenfeld S, Babendreyer A, Groth E, Schumacher J, et al. A transmembrane C-terminal fragment of syndecan-1 is generated by the metalloproteinase ADAM17 and promotes lung epithelial tumor cell migration and lung metastasis formation. Cell Mol Life Sci. 2015;72:3783-801 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Daniele S, Da Pozzo E, Zappelli E, Martini C. Trazodone treatment protects neuronal-like cells from inflammatory insult by inhibiting NF-?B, p38 and JNK. Cell Signal. 2015;27:1609-29 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 2
Huang L, Counter C. Reduced HRAS G12V-Driven Tumorigenesis of Cell Lines Expressing KRAS C118S. PLoS ONE. 2015;10:e0123918 pubmed 出版商
  • 免疫印迹; 人类; 图 5f
Selvaraj N, Kedage V, Hollenhorst P. Comparison of MAPK specificity across the ETS transcription factor family identifies a high-affinity ERK interaction required for ERG function in prostate cells. Cell Commun Signal. 2015;13:12 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 4
Witkiewicz A, McMillan E, Balaji U, Baek G, Lin W, Mansour J, et al. Whole-exome sequencing of pancreatic cancer defines genetic diversity and therapeutic targets. Nat Commun. 2015;6:6744 pubmed 出版商
  • 免疫细胞化学; 小鼠
  • 免疫印迹; 小鼠
Kim T, Lawson M. GnRH Regulates Gonadotropin Gene Expression Through NADPH/Dual Oxidase-Derived Reactive Oxygen Species. Endocrinology. 2015;156:2185-99 pubmed 出版商
  • 免疫印迹; 人类; 图 s21
Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, et al. Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. PLoS ONE. 2015;10:e0119415 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Qu D, Chen Y, Xu X, Zhang M, Zhang Y, Li S. Cbl-b-regulated extracellular signal-regulated kinase signaling is involved in the shikonin-induced apoptosis of lung cancer cells in vitro. Exp Ther Med. 2015;9:1265-1270 pubmed
  • 免疫沉淀; 人类; 图 3
  • 免疫印迹; 人类; 图 s9
Warren D, Tajsic T, Porter L, Minaisah R, Cobb A, Jacob A, et al. Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing. Cell Death Differ. 2015;22:1540-50 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Skarra D, Thackray V. FOXO1 is regulated by insulin and IGF1 in pituitary gonadotropes. Mol Cell Endocrinol. 2015;405:14-24 pubmed 出版商
  • 免疫印迹; 人类
Fouladi F, Jehn L, Metzelder S, Hub F, Henkenius K, Burchert A, et al. Sorafenib induces paradoxical phosphorylation of the extracellular signal-regulated kinase pathway in acute myeloid leukemia cells lacking FLT3-ITD mutation. Leuk Lymphoma. 2015;56:2690-8 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Papadakis A, Sun C, Knijnenburg T, Xue Y, Grernrum W, Hölzel M, et al. SMARCE1 suppresses EGFR expression and controls responses to MET and ALK inhibitors in lung cancer. Cell Res. 2015;25:445-58 pubmed 出版商
  • 免疫印迹; 小鼠
Shaw A, Pickup M, Chytil A, Aakre M, Owens P, Moses H, et al. TGFβ signaling in myeloid cells regulates mammary carcinoma cell invasion through fibroblast interactions. PLoS ONE. 2015;10:e0117908 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Bele A, Mirza S, Zhang Y, Ahmad Mir R, Lin S, Kim J, et al. The cell cycle regulator ecdysoneless cooperates with H-Ras to promote oncogenic transformation of human mammary epithelial cells. Cell Cycle. 2015;14:990-1000 pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Albanito L, Lappano R, Madeo A, Chimento A, Prossnitz E, Cappello A, et al. Effects of atrazine on estrogen receptor α- and G protein-coupled receptor 30-mediated signaling and proliferation in cancer cells and cancer-associated fibroblasts. Environ Health Perspect. 2015;123:493-9 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200
Seaberg B, Henslee G, Wang S, Paez Colasante X, Landreth G, Rimer M. Muscle-derived extracellular signal-regulated kinases 1 and 2 are required for the maintenance of adult myofibers and their neuromuscular junctions. Mol Cell Biol. 2015;35:1238-53 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Schäker K, Bartsch S, Patry C, Stoll S, Hillebrands J, Wieland T, et al. The bipartite rac1 Guanine nucleotide exchange factor engulfment and cell motility 1/dedicator of cytokinesis 180 (elmo1/dock180) protects endothelial cells from apoptosis in blood vessel development. J Biol Chem. 2015;290:6408-18 pubmed 出版商
  • 免疫印迹; 人类
Majuelos Melguizo J, Rodríguez M, López Jiménez L, Rodríguez Vargas J, Martí Martín Consuegra J, Serrano Sáenz S, et al. PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma. Oncotarget. 2015;6:4790-803 pubmed
  • 免疫组化; 人类; 1:100
Zanotto Filho A, Braganhol E, Klafke K, Figueiró F, Terra S, Paludo F, et al. Autophagy inhibition improves the efficacy of curcumin/temozolomide combination therapy in glioblastomas. Cancer Lett. 2015;358:220-31 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Kim E, Kim S, Jin X, Ham S, Kim J, Park J, et al. Epidermal growth factor receptor variant III renders glioma cancer cells less differentiated by JAGGED1. Tumour Biol. 2015;36:2921-8 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Delloye Bourgeois C, Jacquier A, Charoy C, Reynaud F, Nawabi H, Thoinet K, et al. PlexinA1 is a new Slit receptor and mediates axon guidance function of Slit C-terminal fragments. Nat Neurosci. 2015;18:36-45 pubmed 出版商
  • 免疫印迹; 人类
Bernusso V, Machado Neto J, Pericole F, Vieira K, Duarte A, Traina F, et al. Imatinib restores VASP activity and its interaction with Zyxin in BCR-ABL leukemic cells. Biochim Biophys Acta. 2015;1853:388-95 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Tang D, Yu Y, Zhao X, Schachner M, Zhao W. Single chain fragment variable antibodies developed by using as target the 3rd fibronectin type III homologous repeat fragment of human neural cell adhesion molecule L1 promote cell migration and neuritogenesis. Exp Cell Res. 2015;330:336-45 pubmed 出版商
  • 免疫印迹; 人类
Giovannini C, Minguzzi M, Baglioni M, Fornari F, Giannone F, Ravaioli M, et al. Suppression of p53 by Notch3 is mediated by Cyclin G1 and sustained by MDM2 and miR-221 axis in hepatocellular carcinoma. Oncotarget. 2014;5:10607-20 pubmed
  • 免疫印迹; 人类; 图 1
Heynen G, Fonfara A, Bernards R. Resistance to targeted cancer drugs through hepatocyte growth factor signaling. Cell Cycle. 2014;13:3808-17 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500; 图 2
Huang L, Carney J, Cardona D, Counter C. Decreased tumorigenesis in mice with a Kras point mutation at C118. Nat Commun. 2014;5:5410 pubmed 出版商
  • 免疫印迹; 人类
Wang Y, Kuramitsu Y, Tokuda K, Baron B, Kitagawa T, Akada J, et al. Gemcitabine induces poly (ADP-ribose) polymerase-1 (PARP-1) degradation through autophagy in pancreatic cancer. PLoS ONE. 2014;9:e109076 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Kannike K, Sepp M, Zuccato C, Cattaneo E, Timmusk T. Forkhead transcription factor FOXO3a levels are increased in Huntington disease because of overactivated positive autofeedback loop. J Biol Chem. 2014;289:32845-57 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
  • 免疫印迹; 大鼠
Zhang X, Zhang Q, Tu J, Zhu Y, Yang F, Liu B, et al. Prosurvival NMDA 2A receptor signaling mediates postconditioning neuroprotection in the hippocampus. Hippocampus. 2015;25:286-96 pubmed 出版商
  • 免疫印迹; kangaroo rats; 1:200; 图 2
Pilchova I, Klacanova K, Chomova M, Tatarkova Z, Dobrota D, Racay P. Possible contribution of proteins of Bcl-2 family in neuronal death following transient global brain ischemia. Cell Mol Neurobiol. 2015;35:23-31 pubmed 出版商
  • 免疫印迹; 人类
Chang P, Hung C, Wang S, Tsai P, Shih Y, Chen L, et al. Identification and characterization of two novel spliced genes located in the orf47-orf46-orf45 gene locus of Kaposi's sarcoma-associated herpesvirus. J Virol. 2014;88:10092-109 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Rathore K, Cekanova M. Animal model of naturally occurring bladder cancer: characterization of four new canine transitional cell carcinoma cell lines. BMC Cancer. 2014;14:465 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:100
Ishikawa D, Shimada M, Utsunomiya T, Morine Y, Imura S, Ikemoto T, et al. Effect of Twist and Bmi1 on intraductal papillary mucinous neoplasm of the pancreas. J Gastroenterol Hepatol. 2014;29:2032-7 pubmed 出版商
  • 免疫印迹; 牛
Zielniok K, Motyl T, Gajewska M. Functional interactions between 17 ? -estradiol and progesterone regulate autophagy during acini formation by bovine mammary epithelial cells in 3D cultures. Biomed Res Int. 2014;2014:382653 pubmed 出版商
  • 免疫印迹; 人类
Mena H, Lokajczyk A, Dizier B, Strier S, Voto L, Boisson Vidal C, et al. Acidic preconditioning improves the proangiogenic responses of endothelial colony forming cells. Angiogenesis. 2014;17:867-79 pubmed 出版商
  • 免疫印迹; 人类
Attarha S, Andersson S, Mints M, Souchelnytskyi S. Mammalian sterile-like 1 kinase inhibits TGF? and EGF?dependent regulation of invasiveness, migration and proliferation of HEC-1-A endometrial cancer cells. Int J Oncol. 2014;45:853-60 pubmed 出版商
  • 免疫印迹; 人类
Kerdivel G, Boudot A, Habauzit D, Percevault F, Demay F, Pakdel F, et al. Activation of the MKL1/actin signaling pathway induces hormonal escape in estrogen-responsive breast cancer cell lines. Mol Cell Endocrinol. 2014;390:34-44 pubmed 出版商
  • 免疫印迹; 人类
Wei N, Chu E, Wipf P, Schmitz J. Protein kinase d as a potential chemotherapeutic target for colorectal cancer. Mol Cancer Ther. 2014;13:1130-41 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1
Yu P, Laird A, Du X, Wu J, Won K, Yamaguchi K, et al. Characterization of the activity of the PI3K/mTOR inhibitor XL765 (SAR245409) in tumor models with diverse genetic alterations affecting the PI3K pathway. Mol Cancer Ther. 2014;13:1078-91 pubmed 出版商
  • 免疫印迹; 人类
Wang Q, Shen B, Chen L, Zheng P, Feng H, Hao Q, et al. Extracellular calumenin suppresses ERK1/2 signaling and cell migration by protecting fibulin-1 from MMP-13-mediated proteolysis. Oncogene. 2015;34:1006-18 pubmed 出版商
  • 免疫印迹; 人类
Son J, Jeong H, Kim H, Kim Y, Lee E, Lee H, et al. Pelargonidin attenuates PDGF-BB-induced aortic smooth muscle cell proliferation and migration by direct inhibition of focal adhesion kinase. Biochem Pharmacol. 2014;89:236-45 pubmed 出版商
  • 免疫印迹; 人类
Ihunnah C, Wada T, Philips B, Ravuri S, Gibbs R, Kirisci L, et al. Estrogen sulfotransferase/SULT1E1 promotes human adipogenesis. Mol Cell Biol. 2014;34:1682-94 pubmed 出版商
  • 免疫印迹; 小鼠
Wang Y, Kuramitsu Y, Tokuda K, Okada F, Baron B, Akada J, et al. Proteomic analysis indicates that overexpression and nuclear translocation of lactoylglutathione lyase (GLO1) is associated with tumor progression in murine fibrosarcoma. Electrophoresis. 2014;35:2195-202 pubmed 出版商
  • 免疫印迹; 小鼠
Jin Y, Wi H, Choi M, Hong S, Bae Y. Regulation of anti-inflammatory cytokines IL-10 and TGF-? in mouse dendritic cells through treatment with Clonorchis sinensis crude antigen. Exp Mol Med. 2014;46:e74 pubmed 出版商
  • 免疫印迹; 番茄
Gámez M, Calvo M, Selgas M, García M, Erler K, Böhm V, et al. Effect of E-beam treatment on the chemistry and on the antioxidant activity of lycopene from dry tomato peel and tomato powder. J Agric Food Chem. 2014;62:1557-63 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Joannes A, Grelet S, Duca L, Gilles C, Kileztky C, Dalstein V, et al. Fhit regulates EMT targets through an EGFR/Src/ERK/Slug signaling axis in human bronchial cells. Mol Cancer Res. 2014;12:775-83 pubmed 出版商
  • 免疫细胞化学; 大鼠
  • 免疫印迹; 大鼠
Murcia Belmonte V, Medina Rodríguez E, Bribian A, De Castro F, Esteban P. ERK1/2 signaling is essential for the chemoattraction exerted by human FGF2 and human anosmin-1 on newborn rat and mouse OPCs via FGFR1. Glia. 2014;62:374-86 pubmed 出版商
  • 免疫印迹; 人类
Xu C, Chen H, Wang X, Gao J, Che Y, Li Y, et al. S100A14, a member of the EF-hand calcium-binding proteins, is overexpressed in breast cancer and acts as a modulator of HER2 signaling. J Biol Chem. 2014;289:827-37 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Slowik A, Merres J, Elfgen A, Jansen S, Mohr F, Wruck C, et al. Involvement of formyl peptide receptors in receptor for advanced glycation end products (RAGE)--and amyloid beta 1-42-induced signal transduction in glial cells. Mol Neurodegener. 2012;7:55 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Brandenburg L, Jansen S, Albrecht L, Merres J, Gerber J, Pufe T, et al. CpG oligodeoxynucleotides induce the expression of the antimicrobial peptide cathelicidin in glial cells. J Neuroimmunol. 2013;255:18-31 pubmed 出版商
  • 免疫印迹; 大鼠
Kim J, Hwang I, Choi S, Lee H, Lee Y, Goo J, et al. Aqueous extract of Liriope platyphylla, a traditional Chinese medicine, significantly inhibits abdominal fat accumulation and improves glucose regulation in OLETF type II diabetes model rats. Lab Anim Res. 2012;28:181-91 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 3b
Chang J, Adams M, Clifton M, Liao M, Brooks J, Hasdemir B, et al. Urocortin 1 modulates immunosignaling in a rat model of colitis via corticotropin-releasing factor receptor 2. Am J Physiol Gastrointest Liver Physiol. 2011;300:G884-94 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Modi H, Li L, Chu S, Rossi J, Yee J, Bhatia R. Inhibition of Grb2 expression demonstrates an important role in BCR-ABL-mediated MAPK activation and transformation of primary human hematopoietic cells. Leukemia. 2011;25:305-12 pubmed 出版商
Wang C, Lin C, Huang Y, Wang S, Wang Y, Huang B, et al. Sphingosine-1-phosphate promotes PDGF-dependent endothelial progenitor cell angiogenesis in human chondrosarcoma cells. Aging (Albany NY). 2019;11:11040-11053 pubmed 出版商
Huang Y, Zhao J, Mao G, Lee G, Zhang J, Bi L, et al. Identification of novel genetic variants predisposing to familial oral squamous cell carcinomas. Cell Discov. 2019;5:57 pubmed 出版商
Jiang Q, Xie Q, Hu C, Yang Z, Huang P, Shen H, et al. Glioma malignancy is linked to interdependent and inverse AMOG and L1 adhesion molecule expression. BMC Cancer. 2019;19:911 pubmed 出版商
Sang D, Pinglay S, Wiewiora R, Selvan M, Lou H, Chodera J, et al. Ancestral reconstruction reveals mechanisms of ERK regulatory evolution. elife. 2019;8: pubmed 出版商
Lee S, Park S, Lee H, Han S, Song J, Han D, et al. Nedd4 E3 ligase and beta-arrestins regulate ubiquitination, trafficking, and stability of the mGlu7 receptor. elife. 2019;8: pubmed 出版商
Mishra S, Bernal C, Silvano M, Anand S, Ruiz i Altaba A. The protein secretion modulator TMED9 drives CNIH4/TGFα/GLI signaling opposing TMED3-WNT-TCF to promote colon cancer metastases. Oncogene. 2019;: pubmed 出版商
Hocevar B. Loss of Disabled-2 Expression in Pancreatic Cancer Progression. Sci Rep. 2019;9:7532 pubmed 出版商
Wu C, Koay T, Ho Y, Lovat P, Lunec J. TP53 mutant cell lines selected for resistance to MDM2 inhibitors retain growth inhibition by MAPK pathway inhibitors but a reduced apoptotic response. Cancer Cell Int. 2019;19:53 pubmed 出版商
Kizilyer A, Singh M, Singh V, Suwunnakorn S, Palis J, Maggirwar S. Inhibition of Tropomyosin Receptor Kinase A Signaling Negatively Regulates Megakaryopoiesis and induces Thrombopoiesis. Sci Rep. 2019;9:2781 pubmed 出版商
Hepburn A, Steele R, Veeratterapillay R, Wilson L, Kounatidou E, Barnard A, et al. The induction of core pluripotency master regulators in cancers defines poor clinical outcomes and treatment resistance. Oncogene. 2019;38:4412-4424 pubmed 出版商
Bunda S, Heir P, Metcalf J, Li A, Agnihotri S, Pusch S, et al. CIC protein instability contributes to tumorigenesis in glioblastoma. Nat Commun. 2019;10:661 pubmed 出版商
Echeverria P, Bhattacharya K, Joshi A, Wang T, Picard D. The sensitivity to Hsp90 inhibitors of both normal and oncogenically transformed cells is determined by the equilibrium between cellular quiescence and activity. PLoS ONE. 2019;14:e0208287 pubmed 出版商
Knudsen E, Kumarasamy V, Ruiz A, Sivinski J, Chung S, Grant A, et al. Cell cycle plasticity driven by MTOR signaling: integral resistance to CDK4/6 inhibition in patient-derived models of pancreatic cancer. Oncogene. 2019;38:3355-3370 pubmed 出版商
Kano Y, Gebregiworgis T, Marshall C, Radulovich N, Poon B, St Germain J, et al. Tyrosyl phosphorylation of KRAS stalls GTPase cycle via alteration of switch I and II conformation. Nat Commun. 2019;10:224 pubmed 出版商
Fenizia C, Bottino C, Corbetta S, Fittipaldi R, Floris P, Gaudenzi G, et al. SMYD3 promotes the epithelial-mesenchymal transition in breast cancer. Nucleic Acids Res. 2019;47:1278-1293 pubmed 出版商
Athavale D, Chouhan S, Pandey V, Mayengbam S, Singh S, Bhat M. Hepatocellular carcinoma-associated hypercholesterolemia: involvement of proprotein-convertase-subtilisin-kexin type-9 (PCSK9). Cancer Metab. 2018;6:16 pubmed 出版商
Iezzi A, Caiola E, Scagliotti A, Broggini M. Generation and characterization of MEK and ERK inhibitors- resistant non-small-cells-lung-cancer (NSCLC) cells. BMC Cancer. 2018;18:1028 pubmed 出版商
Kim J, Ko M, Gonzales E, Kang R, Kim D, Kim Y, et al. Social support rescues acute stress-induced cognitive impairments by modulating ERK1/2 phosphorylation in adolescent mice. Sci Rep. 2018;8:12003 pubmed 出版商
Bi Y, Jiang M, Guo W, Guan X, Xu M, Ren S, et al. Sex-Dimorphic and Sex Hormone-Dependent Role of Steroid Sulfatase in Adipose Inflammation and Energy Homeostasis. Endocrinology. 2018;159:3365-3377 pubmed 出版商
Ferrandino F, Bernardini G, Tsaouli G, Grazioli P, Campese A, Noce C, et al. Intrathymic Notch3 and CXCR4 combinatorial interplay facilitates T-cell leukemia propagation. Oncogene. 2018;37:6285-6298 pubmed 出版商
Del Rio C, Cantarero I, Palomares B, Gómez Cañas M, Fernandez Ruiz J, Pavicic C, et al. VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB2 receptor-dependent pathways. Br J Pharmacol. 2018;175:3813-3831 pubmed 出版商
Phoomak C, Silsirivanit A, Park D, Sawanyawisuth K, Vaeteewoottacharn K, Wongkham C, et al. O-GlcNAcylation mediates metastasis of cholangiocarcinoma through FOXO3 and MAN1A1. Oncogene. 2018;37:5648-5665 pubmed 出版商
Huang L, Tam K, Liu W, Lin C, Hsu K, Hsieh W, et al. CRISPR/Cas9 Genome Editing of Epidermal Growth Factor Receptor Sufficiently Abolished Oncogenicity in Anaplastic Thyroid Cancer. Dis Markers. 2018;2018:3835783 pubmed 出版商
Vetuschi A, Pompili S, Gallone A, D Alfonso A, Carbone M, Carta G, et al. Immunolocalization of Advanced Glycation End Products, Mitogen Activated Protein Kinases, and Transforming Growth Factor-β/Smads in Pelvic Organ Prolapse. J Histochem Cytochem. 2018;66:673-686 pubmed 出版商
Li X, Shang E, Dong Q, Li Y, Zhang J, Xu S, et al. Small molecules capable of activating DNA methylation-repressed genes targeted by the p38 mitogen-activated protein kinase pathway. J Biol Chem. 2018;293:7423-7436 pubmed 出版商
Collins T, Mao Y, Li H, Bouaziz M, Hong A, Feng G, et al. Crk proteins transduce FGF signaling to promote lens fiber cell elongation. elife. 2018;7: pubmed 出版商
Jeong B, Lee H, Park C, Kang J, Yu S, Choi D, et al. Oxidative stress caused by activation of NADPH oxidase 4 promotes contrast-induced acute kidney injury. PLoS ONE. 2018;13:e0191034 pubmed 出版商
Li S, Mbong E, John D, Terasaka T, Li D, Lawson M. Induction of Stress Signaling In Vitro and Suppression of Gonadotropin Secretion by Free Fatty Acids in Female Mouse Gonadotropes. Endocrinology. 2018;159:1074-1087 pubmed 出版商
Gallagher S, Gunatilake D, Beaumont K, Sharp D, Tiffen J, Heinemann A, et al. HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma. Int J Cancer. 2018;142:1926-1937 pubmed 出版商
Tu Q, Hao J, Zhou X, Yan L, Dai H, Sun B, et al. CDKN2B deletion is essential for pancreatic cancer development instead of unmeaningful co-deletion due to juxtaposition to CDKN2A. Oncogene. 2018;37:128-138 pubmed 出版商
Chen J, Kuo C, Pai P, Ho T, Chen T, Tsai F, et al. Mitochondrial ROS-induced ERK1/2 activation and HSF2-mediated AT1 R upregulation are required for doxorubicin-induced cardiotoxicity. J Cell Physiol. 2018;233:463-475 pubmed 出版商
Ishimoto Y, Inagi R, Yoshihara D, Kugita M, Nagao S, Shimizu A, et al. Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease. Mol Cell Biol. 2017;37: pubmed 出版商
Shin K, Chapman N, Sarker M, Kenward C, Huang S, Weatherbee Martin N, et al. Bioactivity of the putative apelin proprotein expands the repertoire of apelin receptor ligands. Biochim Biophys Acta Gen Subj. 2017;1861:1901-1912 pubmed 出版商
Gbahou F, Cecon E, Viault G, Gerbier R, Jean Alphonse F, Karamitri A, et al. Design and validation of the first cell-impermeant melatonin receptor agonist. Br J Pharmacol. 2017;174:2409-2421 pubmed 出版商
Jia X, Xu J, Gu Y, Gu X, Li W, Wang Y. Vitamin D suppresses oxidative stress-induced microparticle release by human umbilical vein endothelial cells. Biol Reprod. 2017;96:199-210 pubmed 出版商
Ritter Makinson S, Paquet M, Bogenpohl J, Rodin R, Chris Yun C, Weinman E, et al. Group II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain. Neuroscience. 2017;353:58-75 pubmed 出版商
Kwon K, Chung T, Kwak C, Choi H, Kim K, Ha S, et al. Disialyl GD2 ganglioside suppresses ICAM-1-mediated invasiveness in human breast cancer MDA-MB231 cells. Int J Biol Sci. 2017;13:265-275 pubmed 出版商
Lemos L, Miyajima F, Castilho G, Martins D, Pritchard D, Burkitt M. Hexane Extracts of Calophyllum brasiliense Inhibit the Development of Gastric Preneoplasia in Helicobacter felis Infected INS-Gas Mice. Front Pharmacol. 2017;8:92 pubmed 出版商
Hollenbach M, Thonig A, Pohl S, Ripoll C, Michel M, Zipprich A. Expression of glyoxalase-I is reduced in cirrhotic livers: A possible mechanism in the development of cirrhosis. PLoS ONE. 2017;12:e0171260 pubmed 出版商
O Hara S, Splinter P, Trussoni C, Pisarello M, Loarca L, Splinter N, et al. ETS Proto-oncogene 1 Transcriptionally Up-regulates the Cholangiocyte Senescence-associated Protein Cyclin-dependent Kinase Inhibitor 2A. J Biol Chem. 2017;292:4833-4846 pubmed 出版商
Obradović H, Krstić J, Kukolj T, Trivanović D, Đorđević I, Mojsilovic S, et al. Doxycycline Inhibits IL-17-Stimulated MMP-9 Expression by Downregulating ERK1/2 Activation: Implications in Myogenic Differentiation. Mediators Inflamm. 2016;2016:2939658 pubmed 出版商
Ang W, Church A, Kulis M, Choi H, Burks A, Abraham S. Mast cell desensitization inhibits calcium flux and aberrantly remodels actin. J Clin Invest. 2016;126:4103-4118 pubmed 出版商
Yao C, Chow J, Yang C, Kuo H, Chang C, Lee H, et al. Chinese Herbal Mixture, Tien-Hsien Liquid, Induces G2/M Cycle Arrest and Radiosensitivity in MCF-7 Human Breast Cancer Cells through Mechanisms Involving DNMT1 and Rad51 Downregulation. Evid Based Complement Alternat Med. 2016;2016:3251046 pubmed 出版商
Chang R, Pei L, Fang F, Xu J, Yang H, Zuo C, et al. YMO1 suppresses invasion and metastasis by inhibiting RhoC signaling and predicts favorable prognosis in hepatocellular carcinoma. Oncotarget. 2016;7:55585-55600 pubmed 出版商
Caiola E, Brunelli L, Marabese M, Broggini M, Lupi M, Pastorelli R. Different metabolic responses to PI3K inhibition in NSCLC cells harboring wild-type and G12C mutant KRAS. Oncotarget. 2016;7:51462-51472 pubmed 出版商
Kang H, Ahn D, Pak J, Seo K, Baek N, Jang S. Magnobovatol inhibits smooth muscle cell migration by suppressing PDGF-R? phosphorylation and inhibiting matrix metalloproteinase-2 expression. Int J Mol Med. 2016;37:1239-46 pubmed 出版商
Choi H, Lee K, Kim M, Lee K, Shin Y, Cho S, et al. DSGOST inhibits tumor growth by blocking VEGF/VEGFR2-activated angiogenesis. Oncotarget. 2016;7:21775-85 pubmed 出版商
Buffet C, Catelli M, Hecale Perlemoine K, Bricaire L, García C, Gallet Dierick A, et al. Dual Specificity Phosphatase 5, a Specific Negative Regulator of ERK Signaling, Is Induced by Serum Response Factor and Elk-1 Transcription Factor. PLoS ONE. 2015;10:e0145484 pubmed 出版商
Yeh C, Sun H, Huang C, Wong C, Cherng C, Huh B, et al. Long-Term Anti-Allodynic Effect of Immediate Pulsed Radiofrequency Modulation through Down-Regulation of Insulin-Like Growth Factor 2 in a Neuropathic Pain Model. Int J Mol Sci. 2015;16:27156-70 pubmed 出版商
Li X, Shull G, Miguel Qin E, Chen F, Zhuo J. Role of the Na+/H+ exchanger 3 in angiotensin II-induced hypertension in NHE3-deficient mice with transgenic rescue of NHE3 in small intestines. Physiol Rep. 2015;3: pubmed 出版商
Shin J, Chun K, Na Y, Song K, Kim S, Lim J, et al. Allopurinol Protects against Ischemia/Reperfusion-Induced Injury in Rat Urinary Bladders. Oxid Med Cell Longev. 2015;2015:906787 pubmed 出版商
Modi P, Jaiswal S, Sharma P. Regulation of Neuronal Cell Cycle and Apoptosis by MicroRNA 34a. Mol Cell Biol. 2016;36:84-94 pubmed 出版商
Su P, Liu Z, Zhang K, Han X, Saito Y, Xia X, et al. Retinal synaptic regeneration via microfluidic guiding channels. Sci Rep. 2015;5:13591 pubmed 出版商
Marley K, Bracha S, Seguin B. Osteoprotegerin activates osteosarcoma cells that co-express RANK and RANKL. Exp Cell Res. 2015;338:32-8 pubmed 出版商
Sun J, Wang Y, Fu X, Chen Y, Wang D, Li W, et al. Magnolia officinalis Extract Contains Potent Inhibitors against PTP1B and Attenuates Hyperglycemia in db/db Mice. Biomed Res Int. 2015;2015:139451 pubmed 出版商
Saucedo L, Buffa G, Rosso M, Guillardoy T, Góngora A, Munuce M, et al. Fibroblast Growth Factor Receptors (FGFRs) in Human Sperm: Expression, Functionality and Involvement in Motility Regulation. PLoS ONE. 2015;10:e0127297 pubmed 出版商
Dong X, Hu Y, Jing L, Chen J. Role of phosphorylated extracellular signal-regulated kinase, calcitonin gene-related peptide and cyclooxygenase-2 in experimental rat models of migraine. Mol Med Rep. 2015;12:1803-9 pubmed 出版商
Haarmann A, Nowak E, Deiß A, van der Pol S, Monoranu C, Kooij G, et al. Soluble VCAM-1 impairs human brain endothelial barrier integrity via integrin α-4-transduced outside-in signalling. Acta Neuropathol. 2015;129:639-52 pubmed 出版商
Lin W, Lin Y, Shi G, Chang C, Wu H. Lewisy promotes migration of oral cancer cells by glycosylation of epidermal growth factor receptor. PLoS ONE. 2015;10:e0120162 pubmed 出版商
Wei N, Chu E, Wu S, Wipf P, Schmitz J. The cytotoxic effects of regorafenib in combination with protein kinase D inhibition in human colorectal cancer cells. Oncotarget. 2015;6:4745-56 pubmed
Lancaster G, Kraakman M, Kammoun H, Langley K, Estevez E, Banerjee A, et al. The dual-specificity phosphatase 2 (DUSP2) does not regulate obesity-associated inflammation or insulin resistance in mice. PLoS ONE. 2014;9:e111524 pubmed 出版商
Ko S, Ko H, Shieh T, Chang W, Chen H, Chang S, et al. Cell migration is regulated by AGE-RAGE interaction in human oral cancer cells in vitro. PLoS ONE. 2014;9:e110542 pubmed 出版商
Christianson J, Flyer Adams J, Drugan R, Amat J, Daut R, Foilb A, et al. Learned stressor resistance requires extracellular signal-regulated kinase in the prefrontal cortex. Front Behav Neurosci. 2014;8:348 pubmed 出版商
Larios J, Jausoro I, Benítez M, Bronfman F, Marzolo M. Neurotrophins regulate ApoER2 proteolysis through activation of the Trk signaling pathway. BMC Neurosci. 2014;15:108 pubmed 出版商
Witkiewicz A, Cox D, Knudsen E. CDK4/6 inhibition provides a potent adjunct to Her2-targeted therapies in preclinical breast cancer models. Genes Cancer. 2014;5:261-72 pubmed
Landmann H, Proia D, He S, Ogawa L, Kramer F, Beißbarth T, et al. UDP glucuronosyltransferase 1A expression levels determine the response of colorectal cancer cells to the heat shock protein 90 inhibitor ganetespib. Cell Death Dis. 2014;5:e1411 pubmed 出版商
Viluksela M, Heikkinen P, Van der Ven L, Rendel F, Roos R, Esteban J, et al. Toxicological profile of ultrapure 2,2',3,4,4',5,5'-heptachlorbiphenyl (PCB 180) in adult rats. PLoS ONE. 2014;9:e104639 pubmed 出版商
Chang M, Chang H, Wang T, Chan C, Lin B, Yeung S, et al. Antiplatelet effect of catechol is related to inhibition of cyclooxygenase, reactive oxygen species, ERK/p38 signaling and thromboxane A2 production. PLoS ONE. 2014;9:e104310 pubmed 出版商
Attarha S, Saini R, Andersson S, Mints M, Souchelnytskyi S. PKN1 modulates TGFβ and EGF signaling in HEC-1-A endometrial cancer cell line. Onco Targets Ther. 2014;7:1397-408 pubmed 出版商
Chen T, Chiu H, Pan Y, Hsu S, Lin J, Yang K. Intermittent hypoxia-induced protein phosphatase 2A activation reduces PC12 cell proliferation and differentiation. J Biomed Sci. 2014;21:46 pubmed 出版商
Li P, Pan C, Sheu M, Wu C, Ma W, Wu C. Deep sea water prevents balloon angioplasty-induced hyperplasia through MMP-2: an in vitro and in vivo study. PLoS ONE. 2014;9:e96927 pubmed 出版商
Rickard D, Sehon C, Kasparcova V, Kallal L, Haile P, Zeng X, et al. Identification of selective small molecule inhibitors of the nucleotide-binding oligomerization domain 1 (NOD1) signaling pathway. PLoS ONE. 2014;9:e96737 pubmed 出版商
Bartell S, Kim H, Ambrogini E, Han L, Iyer S, Serra Ucer S, et al. FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation. Nat Commun. 2014;5:3773 pubmed 出版商
Guevara T, Sancho M, Perez Paya E, Orzáez M. Role of CDK5/cyclin complexes in ischemia-induced death and survival of renal tubular cells. Cell Cycle. 2014;13:1617-26 pubmed 出版商
Selvaraj N, Budka J, Ferris M, Jerde T, Hollenhorst P. Prostate cancer ETS rearrangements switch a cell migration gene expression program from RAS/ERK to PI3K/AKT regulation. Mol Cancer. 2014;13:61 pubmed 出版商
Mahmud H, Candido W, van Genne L, Vreeswijk Baudoin I, Yu H, van De Sluis B, et al. Cardiac function and architecture are maintained in a model of cardiorestricted overexpression of the prorenin-renin receptor. PLoS ONE. 2014;9:e89929 pubmed 出版商
Ma H, Ng H, Teh X, Li H, Lee Y, Chong Y, et al. Zfp322a Regulates mouse ES cell pluripotency and enhances reprogramming efficiency. PLoS Genet. 2014;10:e1004038 pubmed 出版商
Lo H, Lai T, Li C, Wu W. TNF-? induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways. Acta Pharmacol Sin. 2014;35:339-50 pubmed 出版商
Choudhury R, Roy S, Tsai Y, Tripathy A, Graves L, Wang Z. The splicing activator DAZAP1 integrates splicing control into MEK/Erk-regulated cell proliferation and migration. Nat Commun. 2014;5:3078 pubmed 出版商
Almela P, Garcia Carmona J, Martínez Laorden E, Milanés M, Laorden M. Crosstalk between G protein-coupled receptors (GPCRs) and tyrosine kinase receptor (TXR) in the heart after morphine withdrawal. Front Pharmacol. 2013;4:164 pubmed 出版商
Sastre C, Rubio Navarro A, Buendía I, Gomez Guerrero C, Blanco J, Mas S, et al. Hyperlipidemia-associated renal damage decreases Klotho expression in kidneys from ApoE knockout mice. PLoS ONE. 2013;8:e83713 pubmed 出版商
Bracha S, Viall A, Goodall C, Stang B, Ruaux C, Seguin B, et al. The expression and role of serotonin receptor 5HTR2A in canine osteoblasts and an osteosarcoma cell line. BMC Vet Res. 2013;9:251 pubmed 出版商
Yoshihara D, Kugita M, Sasaki M, Horie S, Nakanishi K, Abe T, et al. Telmisartan ameliorates fibrocystic liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease. PLoS ONE. 2013;8:e81480 pubmed 出版商
Carneiro A, Iaciura B, Nohara L, Lopes C, Veas E, Mariano V, et al. Lysophosphatidylcholine triggers TLR2- and TLR4-mediated signaling pathways but counteracts LPS-induced NO synthesis in peritoneal macrophages by inhibiting NF-?B translocation and MAPK/ERK phosphorylation. PLoS ONE. 2013;8:e76233 pubmed 出版商
Gough D, Koetz L, Levy D. The MEK-ERK pathway is necessary for serine phosphorylation of mitochondrial STAT3 and Ras-mediated transformation. PLoS ONE. 2013;8:e83395 pubmed 出版商
Schulz A, Kyselyova A, Baader S, Jung M, Zoch A, Mautner V, et al. Neuronal merlin influences ERBB2 receptor expression on Schwann cells through neuregulin 1 type III signalling. Brain. 2014;137:420-32 pubmed 出版商
Zhang Z, Liu D, Murugan A, Liu Z, Xing M. Histone deacetylation of NIS promoter underlies BRAF V600E-promoted NIS silencing in thyroid cancer. Endocr Relat Cancer. 2014;21:161-73 pubmed 出版商
Giovannini C, Baglioni M, Baron Toaldo M, Ventrucci C, D Adamo S, Cipone M, et al. Notch3 inhibition enhances sorafenib cytotoxic efficacy by promoting GSK3b phosphorylation and p21 down-regulation in hepatocellular carcinoma. Oncotarget. 2013;4:1618-31 pubmed
Weijts B, van Impel A, Schulte Merker S, de Bruin A. Atypical E2fs control lymphangiogenesis through transcriptional regulation of Ccbe1 and Flt4. PLoS ONE. 2013;8:e73693 pubmed 出版商
Portella L, Vitale R, De Luca S, D Alterio C, Ierano C, Napolitano M, et al. Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases. PLoS ONE. 2013;8:e74548 pubmed 出版商
Dai H, Song D, Xu J, Li B, Hertz L, Peng L. Ammonia-induced Na,K-ATPase/ouabain-mediated EGF receptor transactivation, MAPK/ERK and PI3K/AKT signaling and ROS formation cause astrocyte swelling. Neurochem Int. 2013;63:610-25 pubmed 出版商
Chuang M, Wu S, Tang S, Lai X, Lai H, Hsu K, et al. The HDAC inhibitor LBH589 induces ERK-dependent prometaphase arrest in prostate cancer via HDAC6 inactivation and down-regulation. PLoS ONE. 2013;8:e73401 pubmed 出版商
Rickard D, Sehon C, Kasparcova V, Kallal L, Zeng X, Montoute M, et al. Identification of benzimidazole diamides as selective inhibitors of the nucleotide-binding oligomerization domain 2 (NOD2) signaling pathway. PLoS ONE. 2013;8:e69619 pubmed 出版商
Leskiewicz M, Jantas D, Regulska M, Kaczanowska J, Basta Kaim A, Budziszewska B, et al. Antidepressants attenuate the dexamethasone-induced decrease in viability and proliferation of human neuroblastoma SH-SY5Y cells: a involvement of extracellular regulated kinase (ERK1/2). Neurochem Int. 2013;63:354-62 pubmed 出版商
Cousins E, Nicholas J. Role of human herpesvirus 8 interleukin-6-activated gp130 signal transducer in primary effusion lymphoma cell growth and viability. J Virol. 2013;87:10816-27 pubmed 出版商
Verstraeten S, Jaggers G, Fraga C, Oteiza P. Procyanidins can interact with Caco-2 cell membrane lipid rafts: involvement of cholesterol. Biochim Biophys Acta. 2013;1828:2646-53 pubmed 出版商
Felice D, El Shennawy L, Zhao S, Lantvit D, Shen Q, Unterman T, et al. Growth hormone potentiates 17?-estradiol-dependent breast cancer cell proliferation independently of IGF-I receptor signaling. Endocrinology. 2013;154:3219-27 pubmed 出版商
Gomez Cabello D, Adrados I, Gamarra D, Kobayashi H, Takatsu Y, Takatsu K, et al. DGCR8-mediated disruption of miRNA biogenesis induces cellular senescence in primary fibroblasts. Aging Cell. 2013;12:923-31 pubmed 出版商
Osaki L, Gama P. MAPK signaling pathway regulates p27 phosphorylation at threonin 187 as part of the mechanism triggered by early-weaning to induce cell proliferation in rat gastric mucosa. PLoS ONE. 2013;8:e66651 pubmed 出版商
Agra N, Cidre F, García García L, de la Parra J, Alonso J. Lysyl oxidase is downregulated by the EWS/FLI1 oncoprotein and its propeptide domain displays tumor supressor activities in Ewing sarcoma cells. PLoS ONE. 2013;8:e66281 pubmed 出版商
Minassi A, Sanchez Duffhues G, Collado J, Munoz E, Appendino G. Dissecting the pharmacophore of curcumin. Which structural element is critical for which action?. J Nat Prod. 2013;76:1105-12 pubmed 出版商
Morales Cano D, Calviño E, Rubio V, Herráez A, Sancho P, Tejedor M, et al. Apoptosis induced by paclitaxel via Bcl-2, Bax and caspases 3 and 9 activation in NB4 human leukaemia cells is not modulated by ERK inhibition. Exp Toxicol Pathol. 2013;65:1101-8 pubmed 出版商
Agrawal V, Smart K, Jilling T, Hirsch E. Surfactant protein (SP)-A suppresses preterm delivery and inflammation via TLR2. PLoS ONE. 2013;8:e63990 pubmed 出版商
Munoz Alonso M, Alvarez E, Guillén Navarro M, Pollan M, Aviles P, Galmarini C, et al. c-Jun N-terminal kinase phosphorylation is a biomarker of plitidepsin activity. Mar Drugs. 2013;11:1677-92 pubmed 出版商
Callero M, Luzzani G, De Dios D, Bradshaw T, Perez A. Biomarkers of sensitivity to potent and selective antitumor 2-(4-amino-3-methylphenyl)-5-fluorobenzothiazole (5F203) in ovarian cancer. J Cell Biochem. 2013;114:2392-404 pubmed 出版商
Elliott K, Bourne A, Takayanagi T, Takaguri A, Kobayashi T, Eguchi K, et al. ADAM17 silencing by adenovirus encoding miRNA-embedded siRNA revealed essential signal transduction by angiotensin II in vascular smooth muscle cells. J Mol Cell Cardiol. 2013;62:1-7 pubmed 出版商
Cheng W, Chiao M, Liang Y, Yang Y, Shen C, Yang C. Luteolin inhibits migration of human glioblastoma U-87 MG and T98G cells through downregulation of Cdc42 expression and PI3K/AKT activity. Mol Biol Rep. 2013;40:5315-26 pubmed 出版商
Zhang Y, Zhao Y, Li H, Li Y, Cai X, Shen Y, et al. The nuclear import of oncoprotein hepatitis B X-interacting protein depends on interacting with c-Fos and phosphorylation of both proteins in breast cancer cells. J Biol Chem. 2013;288:18961-74 pubmed 出版商
Foster J, Fish L, Phipps J, Bruker C, Lewis J, Bell J, et al. Odontogenic ameloblast-associated protein (ODAM) inhibits growth and migration of human melanoma cells and elicits PTEN elevation and inactivation of PI3K/AKT signaling. BMC Cancer. 2013;13:227 pubmed 出版商
Crona J, Delgado Verdugo A, Maharjan R, Stalberg P, Granberg D, Hellman P, et al. Somatic mutations in H-RAS in sporadic pheochromocytoma and paraganglioma identified by exome sequencing. J Clin Endocrinol Metab. 2013;98:E1266-71 pubmed 出版商
Ordóñez Morán P, Irmisch A, Barbachano A, Chicote I, Tenbaum S, Landolfi S, et al. SPROUTY2 is a ?-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer. Oncogene. 2014;33:1975-85 pubmed 出版商
Onori P, Mancinelli R, Franchitto A, Carpino G, Renzi A, Brozzetti S, et al. Role of follicle-stimulating hormone on biliary cyst growth in autosomal dominant polycystic kidney disease. Liver Int. 2013;33:914-25 pubmed 出版商
Liu F, Lai M, Chen Y, Lin W, Chang S, Sheu M, et al. Elucidating the inhibitory mechanisms of the ethanolic extract of the fruiting body of the mushroom Antrodia cinnamomea on the proliferation and migration of murine leukemia WEHI-3 cells and their tumorigenicity in a BALB/c allograft tumor model. Phytomedicine. 2013;20:874-82 pubmed 出版商
Yi Y, Hong W, Kang H, Kim H, Zhao W, Wang A, et al. Inhibition of the PI3K/AKT pathway potentiates cytotoxicity of EGFR kinase inhibitors in triple-negative breast cancer cells. J Cell Mol Med. 2013;17:648-56 pubmed 出版商
Schnetzke U, Fischer M, Frietsch J, Finkensieper A, Clement J, Hochhaus A, et al. Paradoxical MAPK-activation in response to treatment with tyrosine kinase inhibitors in CML: flow cytometry loses track. Cytometry B Clin Cytom. 2014;86:229-35 pubmed 出版商
Liu F, Pan C, Lai M, Chang S, Chung J, Wu C. Gan-Lu-Yin Inhibits Proliferation and Migration of Murine WEHI-3 Leukemia Cells and Tumor Growth in BALB/C Allograft Tumor Model. Evid Based Complement Alternat Med. 2013;2013:684071 pubmed 出版商
Abadi A, Crane J, Ogborn D, Hettinga B, Akhtar M, Stokl A, et al. Supplementation with ?-lipoic acid, CoQ10, and vitamin E augments running performance and mitochondrial function in female mice. PLoS ONE. 2013;8:e60722 pubmed 出版商
Oaks A, Frankfurt M, Finkelstein D, Sidhu A. Age-dependent effects of A53T alpha-synuclein on behavior and dopaminergic function. PLoS ONE. 2013;8:e60378 pubmed 出版商
Takayanagi T, Eguchi A, Takaguri A, Hinoki A, Bourne A, Elliott K, et al. A repressor protein, Mnt, is a novel negative regulator of vascular smooth muscle cell hypertrophy by angiotensin II and neointimal hyperplasia by arterial injury. Atherosclerosis. 2013;228:90-3 pubmed 出版商
Chen C, Chen K, Yang T, Liu H, Hsu S. Gallic Acid Induces a Reactive Oxygen Species-Provoked c-Jun NH2-Terminal Kinase-Dependent Apoptosis in Lung Fibroblasts. Evid Based Complement Alternat Med. 2013;2013:613950 pubmed 出版商
Merchant M, Niewczas M, Ficociello L, Lukenbill J, Wilkey D, Li M, et al. Plasma kininogen and kininogen fragments are biomarkers of progressive renal decline in type 1 diabetes. Kidney Int. 2013;83:1177-84 pubmed 出版商
Fosser N, Ronco L, Bejarano A, Paganelli A, Rios H. Calbindin-D28k and calretinin in chicken inner retina during postnatal development and neuroplasticity by dim red light. Dev Neurobiol. 2013;73:530-42 pubmed 出版商
Mukhopadhyay P, Lakshmanan I, Ponnusamy M, Chakraborty S, Jain M, Pai P, et al. MUC4 overexpression augments cell migration and metastasis through EGFR family proteins in triple negative breast cancer cells. PLoS ONE. 2013;8:e54455 pubmed 出版商
Hwang I, Kim J, Lee Y, Kwak M, Choi Y, Kang B, et al. Protective effects of gomisin A isolated from Schisandra chinensis against CCl(4)-induced hepatic and renal injury. Int J Mol Med. 2013;31:888-98 pubmed 出版商
Araújo T, de Oliveira A, Tobar N, Saad M, Moreira L, Reis E, et al. Liver regeneration following partial hepatectomy is improved by enhancing the HGF/Met axis and Akt and Erk pathways after low-power laser irradiation in rats. Lasers Med Sci. 2013;28:1511-7 pubmed 出版商
Moreno J, Sastre C, Madrigal Matute J, Munoz Garcia B, Ortega L, Burkly L, et al. HMGB1 expression and secretion are increased via TWEAK-Fn14 interaction in atherosclerotic plaques and cultured monocytes. Arterioscler Thromb Vasc Biol. 2013;33:612-20 pubmed 出版商
Kauts M, Pihelgas S, Orro K, Neuman T, Piirsoo A. CCL5/CCR1 axis regulates multipotency of human adipose tissue derived stromal cells. Stem Cell Res. 2013;10:166-78 pubmed 出版商
Hanana H, Talarmin H, Pennec J, Droguet M, Morel J, Dorange G. Effect of okadaic acid on cultured clam heart cells: involvement of MAPkinase pathways. Biol Open. 2012;1:1192-9 pubmed 出版商
Mannava S, Moparthy K, Wheeler L, Natarajan V, Zucker S, Fink E, et al. Depletion of deoxyribonucleotide pools is an endogenous source of DNA damage in cells undergoing oncogene-induced senescence. Am J Pathol. 2013;182:142-51 pubmed 出版商
Li S, Wang L, Yan X, Wang Q, Tao Y, Li J, et al. Salvianolic Acid B Attenuates Rat Hepatic Fibrosis via Downregulating Angiotensin II Signaling. Evid Based Complement Alternat Med. 2012;2012:160726 pubmed 出版商
Mei Y, Bian C, Li J, Du Z, Zhou H, Yang Z, et al. miR-21 modulates the ERK-MAPK signaling pathway by regulating SPRY2 expression during human mesenchymal stem cell differentiation. J Cell Biochem. 2013;114:1374-84 pubmed 出版商
Xu J, Song D, Xue Z, Gu L, Hertz L, Peng L. Requirement of glycogenolysis for uptake of increased extracellular K+ in astrocytes: potential implications for K+ homeostasis and glycogen usage in brain. Neurochem Res. 2013;38:472-85 pubmed 出版商
Yang Y, Yang H, Wang Z, Mergler S, Wolosin J, Reinach P. Functional TRPV1 expression in human corneal fibroblasts. Exp Eye Res. 2013;107:121-9 pubmed 出版商
Muller L, Catalano A, Simone R, Cittadini A, Fröhlich K, Böhm V, et al. Antioxidant capacity of tomato seed oil in solution and its redox properties in cultured macrophages. J Agric Food Chem. 2013;61:346-54 pubmed 出版商
Lazarini M, Traina F, Machado Neto J, Barcellos K, Moreira Y, Brandão M, et al. ARHGAP21 is a RhoGAP for RhoA and RhoC with a role in proliferation and migration of prostate adenocarcinoma cells. Biochim Biophys Acta. 2013;1832:365-74 pubmed 出版商
Esteban P, Murcia Belmonte V, García González D, De Castro F. The cysteine-rich region and the whey acidic protein domain are essential for anosmin-1 biological functions. J Neurochem. 2013;124:708-20 pubmed 出版商
Liu S, Li H, Chen L, Yang L, Li L, Tao Y, et al. (-)-Epigallocatechin-3-gallate inhibition of Epstein-Barr virus spontaneous lytic infection involves ERK1/2 and PI3-K/Akt signaling in EBV-positive cells. Carcinogenesis. 2013;34:627-37 pubmed 出版商
Kachroo N, Valencia T, Warren A, Gnanapragasam V. Evidence for downregulation of the negative regulator SPRED2 in clinical prostate cancer. Br J Cancer. 2013;108:597-601 pubmed 出版商
Blich M, Golan A, Arvatz G, Sebbag A, Shafat I, Sabo E, et al. Macrophage activation by heparanase is mediated by TLR-2 and TLR-4 and associates with plaque progression. Arterioscler Thromb Vasc Biol. 2013;33:e56-65 pubmed 出版商
Jeong W, Kim J, Ahn S, Lee S, Bazer F, Han J, et al. AHCYL1 is mediated by estrogen-induced ERK1/2 MAPK cell signaling and microRNA regulation to effect functional aspects of the avian oviduct. PLoS ONE. 2012;7:e49204 pubmed 出版商
Cheng B, Martinez A, Morado J, SCOFIELD V, Roberts J, Maffi S. Retinoic acid protects against proteasome inhibition associated cell death in SH-SY5Y cells via the AKT pathway. Neurochem Int. 2013;62:31-42 pubmed 出版商
de Kreuk B, Anthony E, Geerts D, Hordijk P. The F-BAR protein PACSIN2 regulates epidermal growth factor receptor internalization. J Biol Chem. 2012;287:43438-53 pubmed 出版商
Segar J, Volk K, Lipman M, Scholz T. Thyroid hormone is required for growth adaptation to pressure load in the ovine fetal heart. Exp Physiol. 2013;98:722-33 pubmed 出版商
Yu M, Chen Y, He Y, Podd A, Fu G, Wright J, et al. Critical role of B cell lymphoma 10 in BAFF-regulated NF-?B activation and survival of anergic B cells. J Immunol. 2012;189:5185-93 pubmed 出版商
Ambrosino P, Soldovieri M, Russo C, Taglialatela M. Activation and desensitization of TRPV1 channels in sensory neurons by the PPAR? agonist palmitoylethanolamide. Br J Pharmacol. 2013;168:1430-44 pubmed 出版商
Dalagiorgou G, Piperi C, Georgopoulou U, Adamopoulos C, Basdra E, Papavassiliou A. Mechanical stimulation of polycystin-1 induces human osteoblastic gene expression via potentiation of the calcineurin/NFAT signaling axis. Cell Mol Life Sci. 2013;70:167-180 pubmed 出版商
Takefuji M, Wirth A, Lukasova M, Takefuji S, Boettger T, Braun T, et al. G(13)-mediated signaling pathway is required for pressure overload-induced cardiac remodeling and heart failure. Circulation. 2012;126:1972-82 pubmed 出版商
First M, Gil Ad I, Taler M, Tarasenko I, Novak N, Weizman A. The effects of reboxetine treatment on depression-like behavior, brain neurotrophins, and ERK expression in rats exposed to chronic mild stress. J Mol Neurosci. 2013;50:88-97 pubmed 出版商
Ksionda O, Saveliev A, Köchl R, Rapley J, Faroudi M, Smith Garvin J, et al. Mechanism and function of Vav1 localisation in TCR signalling. J Cell Sci. 2012;125:5302-14 pubmed 出版商
Li Y, Zhang Q, Liu Y, Luo Z, Kang L, Qu J, et al. Hepatitis C virus activates Bcl-2 and MMP-2 expression through multiple cellular signaling pathways. J Virol. 2012;86:12531-43 pubmed 出版商
Lv J, Zhao Z, Chen Y, Wang Q, Tao Y, Yang L, et al. The chinese herbal decoction danggui buxue tang inhibits angiogenesis in a rat model of liver fibrosis. Evid Based Complement Alternat Med. 2012;2012:284963 pubmed 出版商
Fasano E, Serini S, Piccioni E, Toesca A, Monego G, Cittadini A, et al. DHA induces apoptosis by altering the expression and cellular location of GRP78 in colon cancer cell lines. Biochim Biophys Acta. 2012;1822:1762-72 pubmed 出版商
Chase A, Bryant C, Score J, Haferlach C, Grossmann V, Schwaab J, et al. Ruxolitinib as potential targeted therapy for patients with JAK2 rearrangements. Haematologica. 2013;98:404-8 pubmed 出版商
Chase A, Bryant C, Score J, Cross N. Ponatinib as targeted therapy for FGFR1 fusions associated with the 8p11 myeloproliferative syndrome. Haematologica. 2013;98:103-6 pubmed 出版商
Fu G, Chen Y, Schuman J, Wang D, Wen R. Phospholipase C?2 plays a role in TCR signal transduction and T cell selection. J Immunol. 2012;189:2326-32 pubmed 出版商
Modi P, Komaravelli N, Singh N, Sharma P. Interplay between MEK-ERK signaling, cyclin D1, and cyclin-dependent kinase 5 regulates cell cycle reentry and apoptosis of neurons. Mol Biol Cell. 2012;23:3722-30 pubmed 出版商
Takahashi N, Sakurai T, Bozdagi Gunal O, Dorr N, Moy J, Krug L, et al. Increased expression of receptor phosphotyrosine phosphatase-?/? is associated with molecular, cellular, behavioral and cognitive schizophrenia phenotypes. Transl Psychiatry. 2011;1:e8 pubmed 出版商
Taxman D, Lei Y, Zhang S, Holley Guthrie E, Offenbacher S, Ting J. ASC-dependent RIP2 kinase regulates reduced PGE2 production in chronic periodontitis. J Dent Res. 2012;91:877-82 pubmed 出版商
Mustafi R, Dougherty U, Shah H, Dehghan H, Gliksberg A, Wu J, et al. Both stromal cell and colonocyte epidermal growth factor receptors control HCT116 colon cancer cell growth in tumor xenografts. Carcinogenesis. 2012;33:1930-9 pubmed 出版商
Chang M, Chang H, Chan C, Chou H, Chang B, Yeung S, et al. Antiplatelet effect of phloroglucinol is related to inhibition of cyclooxygenase, reactive oxygen species, ERK/p38 signaling and thromboxane A2 production. Toxicol Appl Pharmacol. 2012;263:287-95 pubmed 出版商
Garcia B, Martinez de Mena R, Obregon M. Arachidonic acid stimulates DNA synthesis in brown preadipocytes through the activation of protein kinase C and MAPK. Biochim Biophys Acta. 2012;1821:1309-15 pubmed 出版商
Gonzalo S, Grasa L, Hernández L, Arruebo M, Plaza M, Murillo M. Mitogen activated protein kinases blockade improves lipopolysaccharide-induced ileal motor disturbances. Rev Esp Enferm Dig. 2012;104:305-9 pubmed
Tomlinson D, Baxter E, Loadman P, Hull M, Knowles M. FGFR1-induced epithelial to mesenchymal transition through MAPK/PLC?/COX-2-mediated mechanisms. PLoS ONE. 2012;7:e38972 pubmed 出版商
Lellis Santos C, Sakamoto L, Bromati C, Nogueira T, Leite A, Yamanaka T, et al. The regulation of Rasd1 expression by glucocorticoids and prolactin controls peripartum maternal insulin secretion. Endocrinology. 2012;153:3668-78 pubmed 出版商
Bornachea O, Santos M, Martínez Cruz A, García Escudero R, Dueñas M, Costa C, et al. EMT and induction of miR-21 mediate metastasis development in Trp53-deficient tumours. Sci Rep. 2012;2:434 pubmed 出版商
Tasioudi K, Saetta A, Sakellariou S, Levidou G, Michalopoulos N, Theodorou D, et al. pERK activation in esophageal carcinomas: clinicopathological associations. Pathol Res Pract. 2012;208:398-404 pubmed 出版商
Stefani C, de Oliveira R, Silveira A, Ferraz L, Ribeiro M, Gambero A, et al. Expression of Toll-like receptors in enterocromaffin-like cells and their function in histamine release. Dig Dis Sci. 2012;57:2270-7 pubmed 出版商
Reeves M, Baldwin M, Aragon R, Baldwin S, Chen S, Li X, et al. RASSF1C modulates the expression of a stem cell renewal gene, PIWIL1. BMC Res Notes. 2012;5:239 pubmed 出版商
Wi H, Jin Y, Choi M, Hong S, Bae Y. Predominance of IL-10 and TGF-? production from the mouse macrophage cell line, RAW264.7, in response to crude antigens from Clonorchis sinensis. Cytokine. 2012;59:237-44 pubmed 出版商
Konijeti R, Koyama S, Gray A, Barnard R, Said J, Castor B, et al. Effect of a low-fat diet combined with IGF-1 receptor blockade on 22Rv1 prostate cancer xenografts. Mol Cancer Ther. 2012;11:1539-46 pubmed 出版商
Madrigal Matute J, Fernandez García C, Gomez Guerrero C, Lopez Franco O, Munoz Garcia B, Egido J, et al. HSP90 inhibition by 17-DMAG attenuates oxidative stress in experimental atherosclerosis. Cardiovasc Res. 2012;95:116-23 pubmed 出版商
Popic J, Pesic V, Milanovic D, Todorovic S, Kanazir S, Jevtovic Todorovic V, et al. Propofol-induced changes in neurotrophic signaling in the developing nervous system in vivo. PLoS ONE. 2012;7:e34396 pubmed 出版商
Jang Y, Park H, Kim T, Yang W, Lee J, Choi S, et al. High dose bisphenol A impairs hippocampal neurogenesis in female mice across generations. Toxicology. 2012;296:73-82 pubmed 出版商
Batista T, Alonso Magdalena P, Vieira E, Amaral M, Cederroth C, Nef S, et al. Short-term treatment with bisphenol-A leads to metabolic abnormalities in adult male mice. PLoS ONE. 2012;7:e33814 pubmed 出版商
Kovalská M, Kovalska L, Pavlikova M, Janickova M, Mikuskova K, Adamkov M, et al. Intracellular signaling MAPK pathway after cerebral ischemia-reperfusion injury. Neurochem Res. 2012;37:1568-77 pubmed 出版商
Periyasamy Thandavan S, Takhar S, Singer A, Dohn M, Jackson W, Welborn A, et al. Insulin-like growth factor 1 attenuates antiestrogen- and antiprogestin-induced apoptosis in ER+ breast cancer cells by MEK1 regulation of the BH3-only pro-apoptotic protein Bim. Breast Cancer Res. 2012;14:R52 pubmed
Canepa G, Degese M, Budu A, Garcia C, Buscaglia C. Involvement of TSSA (trypomastigote small surface antigen) in Trypanosoma cruzi invasion of mammalian cells. Biochem J. 2012;444:211-8 pubmed 出版商
Kurdián M, Herrero Fresneda I, Lloberas N, Gimenez Bonafe P, Coria V, Grande M, et al. Delayed mTOR inhibition with low dose of everolimus reduces TGF? expression, attenuates proteinuria and renal damage in the renal mass reduction model. PLoS ONE. 2012;7:e32516 pubmed 出版商
Wan X, Zhao Y, Fan X, Cai H, Zhang Y, Chen M, et al. Molecular prognostic prediction for locally advanced nasopharyngeal carcinoma by support vector machine integrated approach. PLoS ONE. 2012;7:e31989 pubmed 出版商
Lin X, Tang M, Tao Y, Li L, Liu S, Guo L, et al. Epstein-Barr virus-encoded LMP1 triggers regulation of the ERK-mediated Op18/stathmin signaling pathway in association with cell cycle. Cancer Sci. 2012;103:993-9 pubmed 出版商
Kogan M, Fischer Smith T, Kaminsky R, Lehmicke G, Rappaport J. CSF-1R up-regulation is associated with response to pharmacotherapy targeting tyrosine kinase activity in AML cell lines. Anticancer Res. 2012;32:893-9 pubmed
Liu H, Duan Z, Zheng H, Hu D, Li M, Tao Y, et al. EBV-encoded LMP1 upregulates Igκ 3'enhancer activity and Igκ expression in nasopharyngeal cancer cells by activating the Ets-1 through ERKs signaling. PLoS ONE. 2012;7:e32624 pubmed 出版商
Poglitsch M, Weichhart T, Hecking M, Werzowa J, Katholnig K, Antlanger M, et al. CMV late phase-induced mTOR activation is essential for efficient virus replication in polarized human macrophages. Am J Transplant. 2012;12:1458-68 pubmed 出版商
Levidou G, Saetta A, Gigelou F, Karlou M, Papanastasiou P, Stamatelli A, et al. ERK/pERK expression and B-raf mutations in colon adenocarcinomas: correlation with clinicopathological characteristics. World J Surg Oncol. 2012;10:47 pubmed 出版商
Zhou H, Gao J, Zhou L, Li X, Li W, Li X, et al. Ginkgolide B inhibits renal cyst development in in vitro and in vivo cyst models. Am J Physiol Renal Physiol. 2012;302:F1234-42 pubmed 出版商
Lupino E, Ramondetti C, Piccinini M. I?B kinase ? is required for activation of NF-?B and AP-1 in CD3/CD28-stimulated primary CD4(+) T cells. J Immunol. 2012;188:2545-55 pubmed 出版商
Redondo A, Estrella N, Lorenzo A, Cruzado M, Castro C. Quercetin and catechin synergistically inhibit angiotensin II-induced redox-dependent signalling pathways in vascular smooth muscle cells from hypertensive rats. Free Radic Res. 2012;46:619-27 pubmed 出版商
Klag T, Härtel N, Erben P, Schwaab J, Schnetzke U, Schenk T, et al. Omacetaxine mepesuccinate prevents cytokine-dependent resistance to nilotinib in vitro: potential role of the common ?-subunit c of cytokine receptors. Leukemia. 2012;26:1321-8 pubmed 出版商
Bonnefond A, Clément N, Fawcett K, Yengo L, Vaillant E, Guillaume J, et al. Rare MTNR1B variants impairing melatonin receptor 1B function contribute to type 2 diabetes. Nat Genet. 2012;44:297-301 pubmed 出版商
Seo Y, Fukushima H, Maruyama T, Kuroishi K, Osawa K, Nagano K, et al. Accumulation of p100, a precursor of NF-?B2, enhances osteoblastic differentiation in vitro and bone formation in vivo in aly/aly mice. Mol Endocrinol. 2012;26:414-22 pubmed 出版商
Reddiconto G, Toto C, Palamà I, De Leo S, de Luca E, De Matteis S, et al. Targeting of GSK3? promotes imatinib-mediated apoptosis in quiescent CD34+ chronic myeloid leukemia progenitors, preserving normal stem cells. Blood. 2012;119:2335-45 pubmed 出版商
Doi Y, Yashiro M, Yamada N, Amano R, Noda S, Hirakawa K. VEGF-A/VEGFR-2 signaling plays an important role for the motility of pancreas cancer cells. Ann Surg Oncol. 2012;19:2733-43 pubmed 出版商
Cheng M, Quail M, Gingrich D, Ott G, Lu L, Wan W, et al. CEP-28122, a highly potent and selective orally active inhibitor of anaplastic lymphoma kinase with antitumor activity in experimental models of human cancers. Mol Cancer Ther. 2012;11:670-9 pubmed 出版商
Borriello A, Caldarelli I, Basile M, Bencivenga D, Tramontano A, Perrotta S, et al. The tyrosine kinase inhibitor dasatinib induces a marked adipogenic differentiation of human multipotent mesenchymal stromal cells. PLoS ONE. 2011;6:e28555 pubmed 出版商
Iovine B, Iannella M, Nocella F, Pricolo M, Bevilacqua M. Carnosine inhibits KRAS-mediated HCT116 proliferation by affecting ATP and ROS production. Cancer Lett. 2012;315:122-8 pubmed 出版商
Klangjareonchai T, Roongpisuthipong C. The effect of Tinospora crispa on serum glucose and insulin levels in patients with type 2 diabetes mellitus. J Biomed Biotechnol. 2012;2012:808762 pubmed 出版商
Pérez Piñero C, Bruzzone A, Sarappa M, Castillo L, Luthy I. Involvement of ?2- and ?2-adrenoceptors on breast cancer cell proliferation and tumour growth regulation. Br J Pharmacol. 2012;166:721-36 pubmed 出版商
Takayanagi T, Bourne A, Kimura K, Takaguri A, Elliott K, Eguchi K, et al. Constitutive stimulation of vascular smooth muscle cells by angiotensin II derived from an adenovirus encoding a furin-cleavable fusion protein. Am J Hypertens. 2012;25:280-3 pubmed 出版商
Liu R, Liu D, Xing M. The Akt inhibitor MK2206 synergizes, but perifosine antagonizes, the BRAF(V600E) inhibitor PLX4032 and the MEK1/2 inhibitor AZD6244 in the inhibition of thyroid cancer cells. J Clin Endocrinol Metab. 2012;97:E173-82 pubmed 出版商
Valencia T, Joseph A, Kachroo N, Darby S, Meakin S, Gnanapragasam V. Role and expression of FRS2 and FRS3 in prostate cancer. BMC Cancer. 2011;11:484 pubmed 出版商
Da Silva M, Jaggers G, Verstraeten S, Erlejman A, Fraga C, Oteiza P. Large procyanidins prevent bile-acid-induced oxidant production and membrane-initiated ERK1/2, p38, and Akt activation in Caco-2 cells. Free Radic Biol Med. 2012;52:151-9 pubmed 出版商
Dougherty U, Mustafi R, Wang Y, Musch M, Wang C, Konda V, et al. American ginseng suppresses Western diet-promoted tumorigenesis in model of inflammation-associated colon cancer: role of EGFR. BMC Complement Altern Med. 2011;11:111 pubmed 出版商
Minelli R, Serpe L, Pettazzoni P, Minero V, Barrera G, Gigliotti C, et al. Cholesteryl butyrate solid lipid nanoparticles inhibit the adhesion and migration of colon cancer cells. Br J Pharmacol. 2012;166:587-601 pubmed 出版商
Poblete Naredo I, Guillem A, Juárez C, Zepeda R, Ramírez L, Caba M, et al. Brain-derived neurotrophic factor and its receptors in Bergmann glia cells. Neurochem Int. 2011;59:1133-44 pubmed 出版商
Vatsyayan R, Singhal J, Nagaprashantha L, Awasthi S, Singhal S. Nutlin-3 enhances sorafenib efficacy in renal cell carcinoma. Mol Carcinog. 2013;52:39-48 pubmed 出版商
Chang M, Wang T, Yeung S, Jeng P, Liao C, Lin T, et al. Antiplatelet effect by p-cresol, a uremic and environmental toxicant, is related to inhibition of reactive oxygen species, ERK/p38 signaling and thromboxane A2 production. Atherosclerosis. 2011;219:559-65 pubmed 出版商
Ben Lulu S, Coran A, Shehadeh N, Shamir R, Mogilner J, Sukhotnik I. Oral insulin stimulates intestinal epithelial cell turnover following massive small bowel resection in a rat and a cell culture model. Pediatr Surg Int. 2012;28:179-87 pubmed 出版商
Lappas M, Riley C, Lim R, Barker G, Rice G, Menon R, et al. MAPK and AP-1 proteins are increased in term pre-labour fetal membranes overlying the cervix: regulation of enzymes involved in the degradation of fetal membranes. Placenta. 2011;32:1016-25 pubmed 出版商
Casar B, Rodriguez J, Gibor G, Seger R, Crespo P. Mxi2 sustains ERK1/2 phosphorylation in the nucleus by preventing ERK1/2 binding to phosphatases. Biochem J. 2012;441:571-8 pubmed 出版商
Hou P, Liu D, Xing M. Genome-wide alterations in gene methylation by the BRAF V600E mutation in papillary thyroid cancer cells. Endocr Relat Cancer. 2011;18:687-97 pubmed 出版商
Baranwal S, Wang Y, Rathinam R, Lee J, Jin L, McGoey R, et al. Molecular characterization of the tumor-suppressive function of nischarin in breast cancer. J Natl Cancer Inst. 2011;103:1513-28 pubmed 出版商
Klein R, Higgins P. A switch in RND3-RHOA signaling is critical for melanoma cell invasion following mutant-BRAF inhibition. Mol Cancer. 2011;10:114 pubmed 出版商
Son Y, Lee S, Kim S, Jang Y, Chun J, Lee J. Acteoside inhibits melanogenesis in B16F10 cells through ERK activation and tyrosinase down-regulation. J Pharm Pharmacol. 2011;63:1309-19 pubmed 出版商
Shin M, Matsuo K, Tada T, Fukushima H, Furuta H, Ozeki S, et al. The inhibition of RANKL/RANK signaling by osteoprotegerin suppresses bone invasion by oral squamous cell carcinoma cells. Carcinogenesis. 2011;32:1634-40 pubmed 出版商
Kang S, Cho H, Shim G, Lee S, Kim S, Choi H, et al. Cationic liposomal co-delivery of small interfering RNA and a MEK inhibitor for enhanced anticancer efficacy. Pharm Res. 2011;28:3069-78 pubmed 出版商
Lucki N, Li D, Sewer M. Sphingosine-1-phosphate rapidly increases cortisol biosynthesis and the expression of genes involved in cholesterol uptake and transport in H295R adrenocortical cells. Mol Cell Endocrinol. 2012;348:165-75 pubmed 出版商
Hattori N, Carrino D, Lauer M, Vasanji A, Wylie J, Nelson C, et al. Pericellular versican regulates the fibroblast-myofibroblast transition: a role for ADAMTS5 protease-mediated proteolysis. J Biol Chem. 2011;286:34298-310 pubmed 出版商
Mannava S, Omilian A, Wawrzyniak J, Fink E, Zhuang D, Miecznikowski J, et al. PP2A-B56? controls oncogene-induced senescence in normal and tumor human melanocytic cells. Oncogene. 2012;31:1484-92 pubmed 出版商
Li Z, Zhang Z, Xie J, Li X, Tian J, Cai T, et al. Na/K-ATPase mimetic pNaKtide peptide inhibits the growth of human cancer cells. J Biol Chem. 2011;286:32394-403 pubmed 出版商
Zhou D, Pan Y. Gestational low protein diet selectively induces the amino acid response pathway target genes in the liver of offspring rats through transcription factor binding and histone modifications. Biochim Biophys Acta. 2011;1809:549-56 pubmed 出版商
Wittig Blaich S, Kacprzyk L, Eismann T, Bewerunge Hudler M, Kruse P, Winkler E, et al. Matrix-dependent regulation of AKT in Hepsin-overexpressing PC3 prostate cancer cells. Neoplasia. 2011;13:579-89 pubmed
Vega Hernández M, Kovacs A, De Langhe S, Ornitz D. FGF10/FGFR2b signaling is essential for cardiac fibroblast development and growth of the myocardium. Development. 2011;138:3331-40 pubmed 出版商
Mizuguchi H, Terao T, Kitai M, Ikeda M, Yoshimura Y, Das A, et al. Involvement of protein kinase Cdelta/extracellular signal-regulated kinase/poly(ADP-ribose) polymerase-1 (PARP-1) signaling pathway in histamine-induced up-regulation of histamine H1 receptor gene expression in HeLa cells. J Biol Chem. 2011;286:30542-51 pubmed 出版商
Chen L, Qanie D, Jafari A, Taipaleenmaki H, Jensen C, Saamanen A, et al. Delta-like 1/fetal antigen-1 (Dlk1/FA1) is a novel regulator of chondrogenic cell differentiation via inhibition of the Akt kinase-dependent pathway. J Biol Chem. 2011;286:32140-9 pubmed 出版商
Mahmud H, Sillje H, Cannon M, van Gilst W, de Boer R. Regulation of the (pro)renin-renin receptor in cardiac remodelling. J Cell Mol Med. 2012;16:722-9 pubmed 出版商
Zhou D, Zhang Y, Pan Y, Chen H. Dickkopf homolog 1, a Wnt signaling antagonist, is transcriptionally up-regulated via an ATF4-independent and MAPK/ERK-dependent pathway following amino acid deprivation. Biochim Biophys Acta. 2011;1809:306-15 pubmed 出版商
Xing R, Li W, Cui J, Zhang J, Kang B, Wang Y, et al. Gastrokine 1 induces senescence through p16/Rb pathway activation in gastric cancer cells. Gut. 2012;61:43-52 pubmed 出版商
Lee S, Son Y, Kook S, Choi K, Lee J. Ascorbic acid increases the activity and synthesis of tyrosinase in B16F10 cells through activation of p38 mitogen-activated protein kinase. Arch Dermatol Res. 2011;303:669-78 pubmed 出版商
Chatel A, Talarmin H, Hamer B, Schroder H, Muller W, Dorange G. MAP kinase cell signaling pathway as biomarker of environmental pollution in the sponge Suberites domuncula. Ecotoxicology. 2011;20:1727-40 pubmed 出版商
Fiebich B, Collado J, Stratz C, Valina C, Hochholzer W, Munoz E, et al. Pseudoephedrine inhibits T-cell activation by targeting NF-?B, NFAT and AP-1 signaling pathways. Immunopharmacol Immunotoxicol. 2012;34:98-106 pubmed 出版商
Xu C, Gui Q, Chen W, Wu L, Sun W, Zhang N, et al. Small interference RNA targeting tissue factor inhibits human lung adenocarcinoma growth in vitro and in vivo. J Exp Clin Cancer Res. 2011;30:63 pubmed 出版商
Murugan A, Xing M. Anaplastic thyroid cancers harbor novel oncogenic mutations of the ALK gene. Cancer Res. 2011;71:4403-11 pubmed 出版商
Almela P, Martínez Laorden E, Atucha N, Milanes M, Laorden M. Naloxone-precipitated morphine withdrawal evokes phosphorylation of heat shock protein 27 in rat heart through extracellular signal-regulated kinase. J Mol Cell Cardiol. 2011;51:129-39 pubmed 出版商
Ju K, Lim J, Kim K, Kim H. Potential role of NADPH oxidase-mediated activation of Jak2/Stat3 and mitogen-activated protein kinases and expression of TGF-?1 in the pathophysiology of acute pancreatitis. Inflamm Res. 2011;60:791-800 pubmed 出版商
Zaytseva Y, Wallis N, Southard R, Kilgore M. The PPARgamma antagonist T0070907 suppresses breast cancer cell proliferation and motility via both PPARgamma-dependent and -independent mechanisms. Anticancer Res. 2011;31:813-23 pubmed
Saetta A, Levidou G, El Habr E, Panayotidis I, Samaras V, Thymara I, et al. Expression of pERK and pAKT in human astrocytomas: correlation with IDH1-R132H presence, vascular endothelial growth factor, microvascular characteristics and clinical outcome. Virchows Arch. 2011;458:749-59 pubmed 出版商
Lucki N, Sewer M. Genistein stimulates MCF-7 breast cancer cell growth by inducing acid ceramidase (ASAH1) gene expression. J Biol Chem. 2011;286:19399-409 pubmed 出版商
First M, Gil Ad I, Taler M, Tarasenko I, Novak N, Weizman A. The effects of fluoxetine treatment in a chronic mild stress rat model on depression-related behavior, brain neurotrophins and ERK expression. J Mol Neurosci. 2011;45:246-55 pubmed 出版商
Cerliani J, Guillardoy T, Giulianelli S, Vaque J, Gutkind J, Vanzulli S, et al. Interaction between FGFR-2, STAT5, and progesterone receptors in breast cancer. Cancer Res. 2011;71:3720-31 pubmed 出版商
Terra X, Palozza P, Fernandez Larrea J, Ardevol A, Blade C, Pujadas G, et al. Procyanidin dimer B1 and trimer C1 impair inflammatory response signalling in human monocytes. Free Radic Res. 2011;45:611-9 pubmed 出版商
Qu X, Carbe C, Tao C, Powers A, Lawrence R, van Kuppevelt T, et al. Lacrimal gland development and Fgf10-Fgfr2b signaling are controlled by 2-O- and 6-O-sulfated heparan sulfate. J Biol Chem. 2011;286:14435-44 pubmed 出版商
Deng M, Lam S, Meyer U, Feldon J, Li Q, Wei R, et al. Frontal-subcortical protein expression following prenatal exposure to maternal inflammation. PLoS ONE. 2011;6:e16638 pubmed 出版商
Langlais P, Yi Z, Mandarino L. The identification of raptor as a substrate for p44/42 MAPK. Endocrinology. 2011;152:1264-73 pubmed 出版商
de Carné Trécesson S, Guillemin Y, Bélanger A, Bernard A, Preisser L, Ravon E, et al. Escape from p21-mediated oncogene-induced senescence leads to cell dedifferentiation and dependence on anti-apoptotic Bcl-xL and MCL1 proteins. J Biol Chem. 2011;286:12825-38 pubmed 出版商
Mizrachy Schwartz S, Cohen N, Klein S, Kravchenko Balasha N, Levitzki A. Up-regulation of AMP-activated protein kinase in cancer cell lines is mediated through c-Src activation. J Biol Chem. 2011;286:15268-77 pubmed 出版商
Kim H, Kim C, Lee J, Jang S, Hwang J, Ro S, et al. CG0006, a novel histone deacetylase inhibitor, induces breast cancer cell death via histone-acetylation and chaperone-disrupting pathways independent of ER status. Breast Cancer Res Treat. 2011;130:365-75 pubmed 出版商
Lee Y, Kim J, Nam S, Goo J, Choi S, Choi Y, et al. Differential regulation of the biosynthesis of glucose transporters by the PI3-K and MAPK pathways of insulin signaling by treatment with novel compounds from Liriope platyphylla. Int J Mol Med. 2011;27:319-27 pubmed 出版商
Heeg S, Hirt N, Queisser A, Schmieg H, Thaler M, Kunert H, et al. EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis. Cancer Sci. 2011;102:351-60 pubmed 出版商
Yoshihara D, Kurahashi H, Morita M, Kugita M, Hiki Y, Aukema H, et al. PPAR-gamma agonist ameliorates kidney and liver disease in an orthologous rat model of human autosomal recessive polycystic kidney disease. Am J Physiol Renal Physiol. 2011;300:F465-74 pubmed 出版商
Vatsyayan R, Chaudhary P, Sharma A, Sharma R, Rao Lelsani P, Awasthi S, et al. Role of 4-hydroxynonenal in epidermal growth factor receptor-mediated signaling in retinal pigment epithelial cells. Exp Eye Res. 2011;92:147-54 pubmed 出版商
Salvador G, Oteiza P. Iron overload triggers redox-sensitive signals in human IMR-32 neuroblastoma cells. Neurotoxicology. 2011;32:75-82 pubmed 出版商
Cai L, Du T, Song D, Li B, Hertz L, Peng L. Astrocyte ERK phosphorylation precedes K(+)-induced swelling but follows hypotonicity-induced swelling. Neuropathology. 2011;31:250-64 pubmed 出版商
Hueng D, Lin G, Huang S, Liu L, Ju D, Chen Y, et al. Inhibition of Nodal suppresses angiogenesis and growth of human gliomas. J Neurooncol. 2011;104:21-31 pubmed 出版商
Gonzalo S, Grasa L, Arruebo M, Plaza M, Murillo M. Extracellular signal-regulated kinase (ERK) is involved in LPS-induced disturbances in intestinal motility. Neurogastroenterol Motil. 2011;23:e80-90 pubmed 出版商
Huang C, Liu Z, Wang Z, Shen Z, Zhu J. Simvastatin prevents ERK activation in myocardial hypertrophy of spontaneously hypertensive rats. Scand Cardiovasc J. 2010;44:346-51 pubmed 出版商
Martin J, Herbert B, Hocevar B. Disabled-2 downregulation promotes epithelial-to-mesenchymal transition. Br J Cancer. 2010;103:1716-23 pubmed 出版商
Cattaneo F, Guerra G, Ammendola R. Expression and signaling of formyl-peptide receptors in the brain. Neurochem Res. 2010;35:2018-26 pubmed 出版商
Majumdar A, Ghosh A, Datta S, Prudner B, Datta B. p67/MetAP2 suppresses K-RasV12-mediated transformation of NIH3T3 mouse fibroblasts in culture and in athymic mice. Biochemistry. 2010;49:10146-57 pubmed 出版商
Zellmer S, Schmidt Heck W, Godoy P, Weng H, Meyer C, Lehmann T, et al. Transcription factors ETF, E2F, and SP-1 are involved in cytokine-independent proliferation of murine hepatocytes. Hepatology. 2010;52:2127-36 pubmed 出版商
Um H, Kang E, Koo J, Kim H, Jin Lee -, Kim E, et al. Treadmill exercise represses neuronal cell death in an aged transgenic mouse model of Alzheimer's disease. Neurosci Res. 2011;69:161-73 pubmed 出版商
Huang Y, Tanimoto K, Tanne Y, Kamiya T, Kunimatsu R, Michida M, et al. Effects of human full-length amelogenin on the proliferation of human mesenchymal stem cells derived from bone marrow. Cell Tissue Res. 2010;342:205-12 pubmed 出版商
Wang Y, Kuo J, Lee S, Liu J, Hsieh Y, Shih Y, et al. Cobra CRISP functions as an inflammatory modulator via a novel Zn2+- and heparan sulfate-dependent transcriptional regulation of endothelial cell adhesion molecules. J Biol Chem. 2010;285:37872-83 pubmed 出版商
Li Y, Chen J, Wu C, Wang L, Lu M, Chen X. Hepatitis B virus/hepatitis C virus upregulate angiopoietin-2 expression through mitogen-activated protein kinase pathway. Hepatol Res. 2010;40:1022-33 pubmed 出版商
Jiao L, Zhang Y, Hu C, Wang Y, Huang A, He C. Rap1GAP interacts with RET and suppresses GDNF-induced neurite outgrowth. Cell Res. 2011;21:327-37 pubmed 出版商
Nicoletti Carvalho J, Lellis Santos C, Yamanaka T, Nogueira T, Caperuto L, Leite A, et al. MKP-1 mediates glucocorticoid-induced ERK1/2 dephosphorylation and reduction in pancreatic ß-cell proliferation in islets from early lactating mothers. Am J Physiol Endocrinol Metab. 2010;299:E1006-15 pubmed 出版商
Saito Y, Murata Kamiya N, Hirayama T, Ohba Y, Hatakeyama M. Conversion of Helicobacter pylori CagA from senescence inducer to oncogenic driver through polarity-dependent regulation of p21. J Exp Med. 2010;207:2157-74 pubmed 出版商
Agbani E, Coats P, Mills A, Wadsworth R. Peroxynitrite stimulates pulmonary artery endothelial and smooth muscle cell proliferation: involvement of ERK and PKC. Pulm Pharmacol Ther. 2011;24:100-9 pubmed 出版商
Qin L, Han Y. Epigenetic repression of matrix metalloproteinases in myofibroblastic hepatic stellate cells through histone deacetylases 4: implication in tissue fibrosis. Am J Pathol. 2010;177:1915-28 pubmed 出版商
Morand Contant M, Anand Srivastava M, Couture R. Kinin B1 receptor upregulation by angiotensin II and endothelin-1 in rat vascular smooth muscle cells: receptors and mechanisms. Am J Physiol Heart Circ Physiol. 2010;299:H1625-32 pubmed 出版商
Kim S, Kang H, Choi H, Park S. Reduction of Nup107 attenuates the growth factor signaling in the senescent cells. Biochem Biophys Res Commun. 2010;401:131-6 pubmed 出版商
Rice P, Barrett B, Fritz J, Srebernak M, Kisley L, Malkinson A, et al. Regulation of cytokine-induced prostanoid and nitric oxide synthesis by extracellular signal–regulated kinase 1/2 in lung epithelial cells. Exp Lung Res. 2010;36:558-71 pubmed 出版商
Yu W, Ma Y, Flynn G, Muindi J, Kong R, Trump D, et al. Calcitriol enhances gemcitabine anti-tumor activity in vitro and in vivo by promoting apoptosis in a human pancreatic carcinoma model system. Cell Cycle. 2010;9:3022-9 pubmed 出版商
Nguyen K, Intriago R, Upadhyay H, Santos S, Webster N, Lawson M. Modulation of gonadotropin-releasing hormone-induced extracellular signal-regulated kinase activation by dual-specificity protein phosphatase 1 in LbetaT2 gonadotropes. Endocrinology. 2010;151:4882-93 pubmed 出版商
Chaste P, Clement N, Mercati O, Guillaume J, Delorme R, Botros H, et al. Identification of pathway-biased and deleterious melatonin receptor mutants in autism spectrum disorders and in the general population. PLoS ONE. 2010;5:e11495 pubmed 出版商
Dasgupta J, Kar S, Liu R, Joseph J, Kalyanaraman B, Remington S, et al. Reactive oxygen species control senescence-associated matrix metalloproteinase-1 through c-Jun-N-terminal kinase. J Cell Physiol. 2010;225:52-62 pubmed 出版商
Godoy P, Schug M, Bauer A, Hengstler J. Reversible manipulation of apoptosis sensitivity in cultured hepatocytes by matrix-mediated manipulation of signaling activities. Methods Mol Biol. 2010;640:139-55 pubmed 出版商
Oh J, Moon E. Actin-sequestering protein, thymosin beta-4, induces paclitaxel resistance through ROS/HIF-1alpha stabilization in HeLa human cervical tumor cells. Life Sci. 2010;87:286-93 pubmed 出版商
Wang P, Jin T. Hydrogen peroxide stimulates nuclear import of the POU homeodomain protein Oct-1 and its repressive effect on the expression of Cdx-2. BMC Cell Biol. 2010;11:56 pubmed 出版商
Perez M, de Vinuesa A, Sanchez Duffhues G, Marquez N, Bellido M, Munoz Fernandez M, et al. Bryostatin-1 synergizes with histone deacetylase inhibitors to reactivate HIV-1 from latency. Curr HIV Res. 2010;8:418-29 pubmed
Alexandru O, Dragutescu L, Tataranu L, Ciubotaru V, Sevastre A, Georgescu A, et al. Helianthin induces antiproliferative effect on human glioblastoma cells in vitro. J Neurooncol. 2011;102:9-18 pubmed 出版商
Yang J, Huang J, Chatterjee T, Twait E, Fisher R. A novel mechanism involving coordinated regulation of nuclear levels and acetylation of NF-YA and Bcl6 activates RGS4 transcription. J Biol Chem. 2010;285:29760-9 pubmed 出版商
Lage K, Møllgård K, Greenway S, Wakimoto H, Gorham J, Workman C, et al. Dissecting spatio-temporal protein networks driving human heart development and related disorders. Mol Syst Biol. 2010;6:381 pubmed 出版商
Levy C, Slomiansky V, Gattelli A, Nahmod K, Pelisch F, Blaustein M, et al. Tumor necrosis factor alpha induces LIF expression through ERK1/2 activation in mammary epithelial cells. J Cell Biochem. 2010;110:857-65 pubmed 出版商
Bottino M, Cerliani J, Rojas P, Giulianelli S, Soldati R, Mondillo C, et al. Classical membrane progesterone receptors in murine mammary carcinomas: agonistic effects of progestins and RU-486 mediating rapid non-genomic effects. Breast Cancer Res Treat. 2011;126:621-36 pubmed 出版商
Ali I, Penttinen Damdimopoulou P, Mäkelä S, Berglund M, Stenius U, Akesson A, et al. Estrogen-like effects of cadmium in vivo do not appear to be mediated via the classical estrogen receptor transcriptional pathway. Environ Health Perspect. 2010;118:1389-94 pubmed 出版商
Polo M, Arnoni M, Riggio M, Wargon V, Lanari C, Novaro V. Responsiveness to PI3K and MEK inhibitors in breast cancer. Use of a 3D culture system to study pathways related to hormone independence in mice. PLoS ONE. 2010;5:e10786 pubmed 出版商
Boccara F, Auclair M, Cohen A, Lefèvre C, Prot M, Bastard J, et al. HIV protease inhibitors activate the adipocyte renin angiotensin system. Antivir Ther. 2010;15:363-75 pubmed 出版商
Wang T, Chao A, Tsai C, Chang C, Chen S, Lee Y, et al. Stress-induced phosphoprotein 1 as a secreted biomarker for human ovarian cancer promotes cancer cell proliferation. Mol Cell Proteomics. 2010;9:1873-84 pubmed 出版商
Pan W, Zhu S, Yuan M, Cui H, Wang L, Luo X, et al. MicroRNA-21 and microRNA-148a contribute to DNA hypomethylation in lupus CD4+ T cells by directly and indirectly targeting DNA methyltransferase 1. J Immunol. 2010;184:6773-81 pubmed 出版商
Thomas S, Alam R, Lemke N, Schultz L, Gutierrez J, Rempel S. PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling. Neuro Oncol. 2010;12:941-55 pubmed 出版商
Kuohung W, Burnett M, Mukhtyar D, Schuman E, Ni J, Crowley W, et al. A high-throughput small-molecule ligand screen targeted to agonists and antagonists of the G-protein-coupled receptor GPR54. J Biomol Screen. 2010;15:508-17 pubmed 出版商
Bi S, Liu J, Li Y, Wang Q, Liu H, Yan Y, et al. gamma-Tocotrienol modulates the paracrine secretion of VEGF induced by cobalt(II) chloride via ERK signaling pathway in gastric adenocarcinoma SGC-7901 cell line. Toxicology. 2010;274:27-33 pubmed 出版商
Li B, Zhang S, Li M, Hertz L, Peng L. Serotonin increases ERK1/2 phosphorylation in astrocytes by stimulation of 5-HT2B and 5-HT2C receptors. Neurochem Int. 2010;57:432-9 pubmed 出版商
Irusta G, Abramovich D, Parborell F, Tesone M. Direct survival role of vascular endothelial growth factor (VEGF) on rat ovarian follicular cells. Mol Cell Endocrinol. 2010;325:93-100 pubmed 出版商
Carrillo Sepúlveda M, Barreto Chaves M. Phenotypic modulation of cultured vascular smooth muscle cells: a functional analysis focusing on MLC and ERK1/2 phosphorylation. Mol Cell Biochem. 2010;341:279-89 pubmed 出版商
Kawada M, Usami I, Someno T, Watanabe T, Abe H, Inoue H, et al. NBRI17671, a new antitumor compound, produced by Acremonium sp. CR17671. J Antibiot (Tokyo). 2010;63:237-43 pubmed 出版商
Wu X, Lin D, Li G, Zuo Z. Statin post-treatment provides protection against simulated ischemia in bovine pulmonary arterial endothelial cells. Eur J Pharmacol. 2010;636:114-20 pubmed 出版商
Rivas Fuentes S, Garcia Garcia E, Nieto Castañeda G, Rosales C. Fcgamma receptors exhibit different phagocytosis potential in human neutrophils. Cell Immunol. 2010;263:114-21 pubmed 出版商
Aumo L, Rusten M, Mellgren G, Bakke M, Lewis A. Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells. Endocrinology. 2010;151:2151-61 pubmed 出版商
Gotoh K, Tanaka Y, Nishikimi A, Nakamura R, Yamada H, Maeda N, et al. Selective control of type I IFN induction by the Rac activator DOCK2 during TLR-mediated plasmacytoid dendritic cell activation. J Exp Med. 2010;207:721-30 pubmed 出版商
Pan Y, Carbe C, Powers A, Feng G, Zhang X. Sprouty2-modulated Kras signaling rescues Shp2 deficiency during lens and lacrimal gland development. Development. 2010;137:1085-93 pubmed 出版商
Navarrete C, Perez M, de Vinuesa A, Collado J, Fiebich B, Calzado M, et al. Endogenous N-acyl-dopamines induce COX-2 expression in brain endothelial cells by stabilizing mRNA through a p38 dependent pathway. Biochem Pharmacol. 2010;79:1805-14 pubmed 出版商
Wang L, Ankati H, Akubathini S, Balderamos M, Storey C, Patel A, et al. Identification of novel 1,4-benzoxazine compounds that are protective in tissue culture and in vivo models of neurodegeneration. J Neurosci Res. 2010;88:1970-84 pubmed 出版商
Pellegrini M, Di Siena S, Claps G, Di Cesare S, Dolci S, Rossi P, et al. Microgravity promotes differentiation and meiotic entry of postnatal mouse male germ cells. PLoS ONE. 2010;5:e9064 pubmed 出版商
Kim Y, Woo H, Kim B, Lee Y, Kang S, Cho Y, et al. Risk assessment of hydroquinone: differential responses of cell growth and lethality correlated to hydroquinone concentration. J Toxicol Environ Health A. 2009;72:1272-8 pubmed 出版商
Zhang L, Hou S, Wang D, Wu K, Xia L. Effects of thioglycolic acid on progesterone-induced maturation of Xenopus oocytes. J Toxicol Environ Health A. 2009;72:1123-31 pubmed 出版商
Samovski D, Kalderon B, Yehuda Shnaidman E, Bar Tana J. Gating of the mitochondrial permeability transition pore by long chain fatty acyl analogs in vivo. J Biol Chem. 2010;285:6879-90 pubmed 出版商
Grande M, Fuentes Calvo I, Arevalo M, Heredia F, Santos E, Martinez Salgado C, et al. Deletion of H-Ras decreases renal fibrosis and myofibroblast activation following ureteral obstruction in mice. Kidney Int. 2010;77:509-18 pubmed 出版商
Johnston M, Wang A, Catarino M, Ball L, Phan V, MacDonald J, et al. Extracts of the rat tapeworm, Hymenolepis diminuta, suppress macrophage activation in vitro and alleviate chemically induced colitis in mice. Infect Immun. 2010;78:1364-75 pubmed 出版商
Hou P, Bojdani E, Xing M. Induction of thyroid gene expression and radioiodine uptake in thyroid cancer cells by targeting major signaling pathways. J Clin Endocrinol Metab. 2010;95:820-8 pubmed 出版商
Chatel A, Hamer B, Talarmin H, Dorange G, Schroder H, Muller W. Activation of MAP kinase signaling pathway in the mussel Mytilus galloprovincialis as biomarker of environmental pollution. Aquat Toxicol. 2010;96:247-55 pubmed 出版商
Meltser I, Tahera Y, Canlon B. Differential activation of mitogen-activated protein kinases and brain-derived neurotrophic factor after temporary or permanent damage to a sensory system. Neuroscience. 2010;165:1439-46 pubmed 出版商
Castro C, Lorenzo A, Gonzalez A, Cruzado M. Garlic components inhibit angiotensin II-induced cell-cycle progression and migration: Involvement of cell-cycle inhibitor p27(Kip1) and mitogen-activated protein kinase. Mol Nutr Food Res. 2010;54:781-7 pubmed 出版商
Yao C, Yang C, Chuang S, Yan J, Liu C, Chen S, et al. Targeting PML-RAR? and Oncogenic Signaling Pathways by Chinese Herbal Mixture Tien-Hsien Liquid in Acute Promyelocytic Leukemia NB4 Cells. Evid Based Complement Alternat Med. 2011;2011:984154 pubmed 出版商
Avila L, Perez M, Sanchez Duffhues G, Hernandez Galan R, Munoz E, Cabezas F, et al. Effects of diterpenes from latex of Euphorbia lactea and Euphorbia laurifolia on human immunodeficiency virus type 1 reactivation. Phytochemistry. 2010;71:243-8 pubmed 出版商
Béraud Dufour S, Coppola T, Massa F, Mazella J. Neurotensin receptor-2 and -3 are crucial for the anti-apoptotic effect of neurotensin on pancreatic beta-TC3 cells. Int J Biochem Cell Biol. 2009;41:2398-402 pubmed
Lee D, Li Y, Chang S, Zhou J, Ho H, Chiu J, et al. Oscillatory flow-induced proliferation of osteoblast-like cells is mediated by alphavbeta3 and beta1 integrins through synergistic interactions of focal adhesion kinase and Shc with phosphatidylinositol 3-kinase and the Akt/mTOR/p70S6K pathway. J Biol Chem. 2010;285:30-42 pubmed 出版商
Girasol A, Albuquerque G, Mansour E, Araujo E, Degasperi G, Denis R, et al. Fyn mediates leptin actions in the thymus of rodents. PLoS ONE. 2009;4:e7707 pubmed 出版商
Moumtzi S, Roberts M, Joyce T, Evangelidou M, Probert L, Frillingos S, et al. Gene expression profile associated with oncogenic ras-induced senescence, cell death, and transforming properties in human cells. Cancer Invest. 2010;28:563-87 pubmed 出版商
Warren D, Tajsic T, Mellad J, Searles R, Zhang Q, Shanahan C. Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation. J Biol Chem. 2010;285:1311-20 pubmed 出版商
Gu L, Hu X, Xue Z, Yang J, Wan L, Ren Y, et al. Potent homocysteine-induced ERK phosphorylation in cultured neurons depends on self-sensitization via system Xc(-). Toxicol Appl Pharmacol. 2010;242:209-23 pubmed 出版商
Chen D, Lin Q, Box N, ROOP D, Ishii S, Matsuzaki K, et al. SKI knockdown inhibits human melanoma tumor growth in vivo. Pigment Cell Melanoma Res. 2009;22:761-72 pubmed 出版商
Yeh C, Chiu J, Lee C, Lee P, Shih Y, Sun J, et al. Estrogen augments shear stress-induced signaling and gene expression in osteoblast-like cells via estrogen receptor-mediated expression of beta1-integrin. J Bone Miner Res. 2010;25:627-39 pubmed 出版商
Mani A, Fenwick M, Cheng Z, Sharma M, Singh D, Wathes D. IGF1 induces up-regulation of steroidogenic and apoptotic regulatory genes via activation of phosphatidylinositol-dependent kinase/AKT in bovine granulosa cells. Reproduction. 2010;139:139-51 pubmed 出版商
Grasset M, Gobert Gosse S, Mouchiroud G, Bourette R. Macrophage differentiation of myeloid progenitor cells in response to M-CSF is regulated by the dual-specificity phosphatase DUSP5. J Leukoc Biol. 2010;87:127-35 pubmed 出版商
Lai C, Tseng J, Lee Y, Chen Y, Lee J, Lin B, et al. Translational up-regulation of Aurora-A in EGFR-overexpressed cancer. J Cell Mol Med. 2010;14:1520-31 pubmed 出版商
Hong S, Jeon Y, Lee H, Kim J, Baek J, Lee J. Activation of RhoA and FAK induces ERK-mediated osteopontin expression in mechanical force-subjected periodontal ligament fibroblasts. Mol Cell Biochem. 2010;335:263-72 pubmed 出版商
Rafacho A, Giozzet V, Boschero A, Abrantes J, Cestari T, Carneiro E, et al. Reduced pancreatic beta-cell mass is associated with decreased FoxO1 and Erk1/2 protein phosphorylation in low-protein malnourished rats. Braz J Med Biol Res. 2009;42:935-41 pubmed
Langenheim J, Chen W. Improving the pharmacokinetics/pharmacodynamics of prolactin, GH, and their antagonists by fusion to a synthetic albumin-binding peptide. J Endocrinol. 2009;203:375-87 pubmed 出版商
Al Anati L, Hogberg J, Stenius U. Non-dioxin-like-PCBs phosphorylate Mdm2 at Ser166 and attenuate the p53 response in HepG2 cells. Chem Biol Interact. 2009;182:191-8 pubmed 出版商
Grundt A, Grafe I, Liegibel U, Sommer U, Nawroth P, Kasperk C. Direct effects of osteoprotegerin on human bone cell metabolism. Biochem Biophys Res Commun. 2009;389:550-5 pubmed 出版商
Fiore A, Fuziwara C, Kimura E. High iodine concentration attenuates RET/PTC3 oncogene activation in thyroid follicular cells. Thyroid. 2009;19:1249-56 pubmed 出版商
Lee S, Lim J, Kim H. Activator protein-1 mediates docosahexaenoic acid-induced apoptosis of human gastric cancer cells. Ann N Y Acad Sci. 2009;1171:163-9 pubmed 出版商
Reinking B, Wedemeyer E, Weiss R, Segar J, Scholz T. Cardiomyopathy in offspring of diabetic rats is associated with activation of the MAPK and apoptotic pathways. Cardiovasc Diabetol. 2009;8:43 pubmed 出版商
Ahluwalia A, Li A, Cheng G, Deng X, Tarnawski A. Reduced ghrelin in endothelial cells plays important mechanistic role in aging-related impairment of angiogenesis. J Physiol Pharmacol. 2009;60:29-34 pubmed
Quaglino A, Salierno M, Pellegrotti J, Rubinstein N, Kordon E. Mechanical strain induces involution-associated events in mammary epithelial cells. BMC Cell Biol. 2009;10:55 pubmed 出版商
Hou P, Liu D, Ji M, Liu Z, Engles J, Wahl R, et al. Induction of thyroid gene expression and radioiodine uptake in melanoma cells: novel therapeutic implications. PLoS ONE. 2009;4:e6200 pubmed 出版商
Papachroni K, Piperi C, Levidou G, Korkolopoulou P, Pawelczyk L, Diamanti Kandarakis E, et al. Lysyl oxidase interacts with AGE signalling to modulate collagen synthesis in polycystic ovarian tissue. J Cell Mol Med. 2010;14:2460-9 pubmed 出版商
Meng Y, Zou E. Impacts of molt-inhibiting organochlorine compounds on epidermal ecdysteroid signaling in the fiddler crab, Uca pugilator, in vitro. Comp Biochem Physiol C Toxicol Pharmacol. 2009;150:436-41 pubmed 出版商
Ronca R, Gualandi L, Crescini E, Calza S, Presta M, Dell Era P. Fibroblast growth factor receptor-1 phosphorylation requirement for cardiomyocyte differentiation in murine embryonic stem cells. J Cell Mol Med. 2009;13:1489-98 pubmed 出版商
Bontempo P, Mita L, Doto A, Miceli M, Nebbioso A, Lepore I, et al. Molecular analysis of the apoptotic effects of BPA in acute myeloid leukemia cells. J Transl Med. 2009;7:48 pubmed 出版商
Fernandez M, Bianchi M, Lux Lantos V, Libertun C. Neonatal exposure to bisphenol a alters reproductive parameters and gonadotropin releasing hormone signaling in female rats. Environ Health Perspect. 2009;117:757-62 pubmed 出版商
Degasperi G, Denis R, Morari J, Solon C, Geloneze B, Stabe C, et al. Reactive oxygen species production is increased in the peripheral blood monocytes of obese patients. Metabolism. 2009;58:1087-95 pubmed 出版商
Xue A, Xue M, Jackson C, Smith R. Suppression of urokinase plasminogen activator receptor inhibits proliferation and migration of pancreatic adenocarcinoma cells via regulation of ERK/p38 signaling. Int J Biochem Cell Biol. 2009;41:1731-8 pubmed 出版商
Palozza P, Torelli C, Boninsegna A, Simone R, Catalano A, Mele M, et al. Growth-inhibitory effects of the astaxanthin-rich alga Haematococcus pluvialis in human colon cancer cells. Cancer Lett. 2009;283:108-17 pubmed 出版商
Sucher R, Gehwolf P, Kaier T, Hermann M, Maglione M, Oberhuber R, et al. Intracellular signaling pathways control mitochondrial events associated with the development of ischemia/ reperfusion-associated damage. Transpl Int. 2009;22:922-30 pubmed 出版商
Meltser I, Tahera Y, Canlon B. Glucocorticoid receptor and mitogen-activated protein kinase activity after restraint stress and acoustic trauma. J Neurotrauma. 2009;26:1835-45 pubmed 出版商
Tai P, Shiraishi K, Ascoli M. Activation of the lutropin/choriogonadotropin receptor inhibits apoptosis of immature Leydig cells in primary culture. Endocrinology. 2009;150:3766-73 pubmed 出版商
Karlou M, Saetta A, Korkolopoulou P, Levidou G, Papanastasiou P, Boltetsou E, et al. Activation of extracellular regulated kinases (ERK1/2) predicts poor prognosis in urothelial bladder carcinoma and is not associated with B-Raf gene mutations. Pathology. 2009;41:327-34 pubmed 出版商
Seo J, Kim T, Leem Y, Lee K, Park S, Baek I, et al. SK-PC-B70M confers anti-oxidant activity and reduces Abeta levels in the brain of Tg2576 mice. Brain Res. 2009;1261:100-8 pubmed 出版商
Zeiller C, Mebarek S, Jaafar R, Pirola L, Lagarde M, Prigent A, et al. Phospholipase D2 regulates endothelial permeability through cytoskeleton reorganization and occludin downregulation. Biochim Biophys Acta. 2009;1793:1236-49 pubmed 出版商
Zheng F, Xu Y, Yang R, Wu B, Tan X, Qin Y, et al. Combination effect of oncolytic adenovirus therapy and herpes simplex virus thymidine kinase/ganciclovir in hepatic carcinoma animal models. Acta Pharmacol Sin. 2009;30:617-27 pubmed 出版商
Meyer Bahlburg A, Bandaranayake A, Andrews S, Rawlings D. Reduced c-myc expression levels limit follicular mature B cell cycling in response to TLR signals. J Immunol. 2009;182:4065-75 pubmed 出版商
Porzionato A, Macchi V, Parenti A, De Caro R. Extracellular signal-regulated kinase and phosphatidylinositol-3-kinase/AKT signalling pathways in the human carotid body and peripheral ganglia. Acta Histochem. 2010;112:305-16 pubmed 出版商
Al Mahmood S, Colin S, Farhat N, Thorin E, Steverlynck C, Chemtob S. Potent in vivo antiangiogenic effects of GS-101 (5'-TATCCGGAGGGCTCGCCATGCTGCT-3'), an antisense oligonucleotide preventing the expression of insulin receptor substrate-1. J Pharmacol Exp Ther. 2009;329:496-504 pubmed 出版商
Kook S, Son Y, Hwang J, Kim E, Lee C, Jeon Y, et al. Mechanical force inhibits osteoclastogenic potential of human periodontal ligament fibroblasts through OPG production and ERK-mediated signaling. J Cell Biochem. 2009;106:1010-9 pubmed 出版商
Kook S, Hwang J, Park J, Kim E, Heo J, Jeon Y, et al. Mechanical force induces type I collagen expression in human periodontal ligament fibroblasts through activation of ERK/JNK and AP-1. J Cell Biochem. 2009;106:1060-7 pubmed 出版商
Chen J, Rusnak M, Lombroso P, Sidhu A. Dopamine promotes striatal neuronal apoptotic death via ERK signaling cascades. Eur J Neurosci. 2009;29:287-306 pubmed 出版商
Hu C, Wu Y, Wan Y, Wang Q, Song J. Introduction of hIGF-1 gene into bone marrow stromal cells and its effects on the cell's biological behaviors. Cell Transplant. 2008;17:1067-81 pubmed
Momose I, Kunimoto S, Osono M, Ikeda D. Inhibitors of insulin-like growth factor-1 receptor tyrosine kinase are preferentially cytotoxic to nutrient-deprived pancreatic cancer cells. Biochem Biophys Res Commun. 2009;380:171-6 pubmed 出版商
Palozza P, Simone R, Catalano A, Boninsegna A, Böhm V, Fröhlich K, et al. Lycopene prevents 7-ketocholesterol-induced oxidative stress, cell cycle arrest and apoptosis in human macrophages. J Nutr Biochem. 2010;21:34-46 pubmed 出版商
Almela P, Victoria Milanés M, Luisa Laorden M. Tyrosine hydroxylase phosphorylation after naloxone-induced morphine withdrawal in the left ventricle. Basic Res Cardiol. 2009;104:366-76 pubmed 出版商
Deng C, Ueda E, Chen K, Bula C, Norman A, Luben R, et al. Prolactin blocks nuclear translocation of VDR by regulating its interaction with BRCA1 in osteosarcoma cells. Mol Endocrinol. 2009;23:226-36 pubmed 出版商
Rahmouni K, Sigmund C, Haynes W, Mark A. Hypothalamic ERK mediates the anorectic and thermogenic sympathetic effects of leptin. Diabetes. 2009;58:536-42 pubmed 出版商
Samuels A, Klinken S, Ingley E. Liar, a novel Lyn-binding nuclear/cytoplasmic shuttling protein that influences erythropoietin-induced differentiation. Blood. 2009;113:3845-56 pubmed 出版商
Park M, Oh H, York D. Enterostatin affects cyclic AMP and ERK signaling pathways to regulate Agouti-related protein (AgRP) expression. Peptides. 2009;30:181-90 pubmed 出版商
Li N, Fu H, Tie Y, Hu Z, Kong W, Wu Y, et al. miR-34a inhibits migration and invasion by down-regulation of c-Met expression in human hepatocellular carcinoma cells. Cancer Lett. 2009;275:44-53 pubmed 出版商
Sukhotnik I, Hayari L, Bashenko Y, Chemodanov E, Mogilner J, Shamir R, et al. Dietary palmitic acid modulates intestinal re-growth after massive small bowel resection in a rat. Pediatr Surg Int. 2008;24:1313-21 pubmed 出版商
Namdari S, Wei L, Moore D, Chen Q. Reduced limb length and worsened osteoarthritis in adult mice after genetic inhibition of p38 MAP kinase activity in cartilage. Arthritis Rheum. 2008;58:3520-9 pubmed 出版商
Sukhotnik I, Shteinberg D, Ben Lulu S, Bashenko Y, Mogilner J, Ure B, et al. Transforming growth factor-alpha stimulates enterocyte proliferation and accelerates intestinal recovery following methotrexate-induced intestinal mucositis in a rat and a cell culture model. Pediatr Surg Int. 2008;24:1303-11 pubmed 出版商
Fukuda T, Kanomata K, Nojima J, Kokabu S, Akita M, Ikebuchi K, et al. A unique mutation of ALK2, G356D, found in a patient with fibrodysplasia ossificans progressiva is a moderately activated BMP type I receptor. Biochem Biophys Res Commun. 2008;377:905-9 pubmed 出版商
Ruiz E, Hunt T, Nebreda A. Meiotic inactivation of Xenopus Myt1 by CDK/XRINGO, but not CDK/cyclin, via site-specific phosphorylation. Mol Cell. 2008;32:210-20 pubmed 出版商
Pursiheimo J, Rantanen K, Heikkinen P, Johansen T, Jaakkola P. Hypoxia-activated autophagy accelerates degradation of SQSTM1/p62. Oncogene. 2009;28:334-44 pubmed 出版商
Pinkaew D, Cho S, Hui D, Wiktorowicz J, Hutadilok Towatana N, Mahabusarakam W, et al. Morelloflavone blocks injury-induced neointimal formation by inhibiting vascular smooth muscle cell migration. Biochim Biophys Acta. 2009;1790:31-9 pubmed 出版商
Almela P, Garcia Nogales P, Romero A, Milanes M, Laorden M, Puig M. Effects of chronic inflammation and morphine tolerance on the expression of phospho-ERK 1/2 and phospho-P38 in the injured tissue. Naunyn Schmiedebergs Arch Pharmacol. 2009;379:315-23 pubmed 出版商
Ahmed N, Dasari S, Srivastava S, Sneh A, Ahmad A, Islam Khan M, et al. Taxol and 10-deacetylbaccatinIII induce distinct changes in the dynamics of caveolae. FEBS Lett. 2008;582:3595-600 pubmed 出版商
Sukhotnik I, Shteinberg D, Ben Lulu S, Bashenko Y, Mogilner J, Ure B, et al. Effect of transforming growth factor-alpha on enterocyte apoptosis is correlated with EGF receptor expression along the villus-crypt axis during methotrexate-induced intestinal mucositis in a rat. Apoptosis. 2008;13:1344-55 pubmed 出版商
Ma Y, Yu W, Hershberger P, Flynn G, Kong R, Trump D, et al. 1alpha,25-Dihydroxyvitamin D3 potentiates cisplatin antitumor activity by p73 induction in a squamous cell carcinoma model. Mol Cancer Ther. 2008;7:3047-55 pubmed 出版商
Broide E, Scapa E, Bloch O, Shapiro M, Kimchi N, Ben Yehudah G, et al. Evidence for aberrant regulation of MAP kinase signal transduction pathway in peripheral blood mononuclear cells in patients with active celiac disease. Dig Dis Sci. 2009;54:1270-5 pubmed 出版商
Norris R, Freudzon M, Mehlmann L, Cowan A, Simon A, Paul D, et al. Luteinizing hormone causes MAP kinase-dependent phosphorylation and closure of connexin 43 gap junctions in mouse ovarian follicles: one of two paths to meiotic resumption. Development. 2008;135:3229-38 pubmed 出版商
Barbosa H, Bordin S, Anhe G, Persaud S, Bowe J, Borelli M, et al. Islet neogenesis-associated protein signaling in neonatal pancreatic rat islets: involvement of the cholinergic pathway. J Endocrinol. 2008;199:299-306 pubmed 出版商
Chen Y, Wang X, Di L, Fu G, Chen Y, Bai L, et al. Phospholipase Cgamma2 mediates RANKL-stimulated lymph node organogenesis and osteoclastogenesis. J Biol Chem. 2008;283:29593-601 pubmed 出版商
Wargon V, Helguero L, Bolado J, Rojas P, Novaro V, Molinolo A, et al. Reversal of antiprogestin resistance and progesterone receptor isoform ratio in acquired resistant mammary carcinomas. Breast Cancer Res Treat. 2009;116:449-60 pubmed 出版商
Liu D, Xing M. Potent inhibition of thyroid cancer cells by the MEK inhibitor PD0325901 and its potentiation by suppression of the PI3K and NF-kappaB pathways. Thyroid. 2008;18:853-64 pubmed 出版商
Conner M, Hicks M, Dafforn T, Knowles T, Ludwig C, Staddon S, et al. Functional and biophysical analysis of the C-terminus of the CGRP-receptor; a family B GPCR. Biochemistry. 2008;47:8434-44 pubmed 出版商
Wen Q, Ma L, Chen Y, Yang L, Luo W, Wang X. Treatment of avascular necrosis of the femoral head by hepatocyte growth factor-transgenic bone marrow stromal stem cells. Gene Ther. 2008;15:1523-35 pubmed 出版商
Koster F, Engel J, Schally A, Honig A, Schröer A, Seitz S, et al. Triple-negative breast cancers express receptors for growth hormone-releasing hormone (GHRH) and respond to GHRH antagonists with growth inhibition. Breast Cancer Res Treat. 2009;116:273-9 pubmed 出版商
Ligeza A, Wawrzczak Bargiela A, Kaminska D, Korostynski M, Przewlocki R. Regulation of ERK1/2 phosphorylation by acute and chronic morphine - implications for the role of cAMP-responsive element binding factor (CREB)-dependent and Ets-like protein-1 (Elk-1)-dependent transcription; small interfering RNA-based strategy. FEBS J. 2008;275:3836-49 pubmed 出版商
Derin D, Eralp Y, Ozluk Y, Yavuz E, Guney N, Saip P, et al. Lower level of MAPK expression is associated with anthracycline resistance and decreased survival in patients with hormone receptor negative breast cancer. Cancer Invest. 2008;26:671-9 pubmed 出版商
Kim S, Lee Y, Kim Y, Bahk Y. A Proteomic approach for protein-profiling the oncogenic ras induced transformation (H-, K-, and N-Ras) in NIH/3T3 mouse embryonic fibroblasts. Proteomics. 2008;8:3082-93 pubmed 出版商
Oberst M, Beberman S, Zhao L, Yin J, Ward Y, Kelly K. TDAG51 is an ERK signaling target that opposes ERK-mediated HME16C mammary epithelial cell transformation. BMC Cancer. 2008;8:189 pubmed 出版商
Lutaif N, Rocha E, Veloso L, Bento L, Gontijo J. Renal contribution to thermolability in rats: role of renal nerves. Nephrol Dial Transplant. 2008;23:3798-805 pubmed 出版商
Cheng B, Song J, Zou Y, Wang Q, Lei Y, Zhu C, et al. Responses of vascular smooth muscle cells to estrogen are dependent on balance between ERK and p38 MAPK pathway activities. Int J Cardiol. 2009;134:356-65 pubmed 出版商
Zhang S, Qiu X, Gu Y, Wang E. Up-regulation of proline-rich tyrosine kinase 2 in non-small cell lung cancer. Lung Cancer. 2008;62:295-301 pubmed 出版商
Nunez C, Castells M, Laorden M, Milanes M. Regulation of extracellular signal-regulated kinases (ERKs) by naloxone-induced morphine withdrawal in the brain stress system. Naunyn Schmiedebergs Arch Pharmacol. 2008;378:407-20 pubmed 出版商
Almela P, Milanés M, Laorden M. The PKs PKA and ERK 1/2 are involved in phosphorylation of TH at Serine 40 and 31 during morphine withdrawal in rat hearts. Br J Pharmacol. 2008;155:73-83 pubmed 出版商
Johnson S, Shah N, Bajer A, Lebien T. IL-7 activates the phosphatidylinositol 3-kinase/AKT pathway in normal human thymocytes but not normal human B cell precursors. J Immunol. 2008;180:8109-17 pubmed
Peralta E, Brewer A, Louis S, Dunnington G. Vitamin E increases biomarkers of estrogen stimulation when taken with tamoxifen. J Surg Res. 2009;153:143-7 pubmed 出版商
Lin H, Lee E, Hestir K, Leo C, Huang M, Bosch E, et al. Discovery of a cytokine and its receptor by functional screening of the extracellular proteome. Science. 2008;320:807-11 pubmed 出版商
Graupera M, Guillermet Guibert J, Foukas L, Phng L, Cain R, Salpekar A, et al. Angiogenesis selectively requires the p110alpha isoform of PI3K to control endothelial cell migration. Nature. 2008;453:662-6 pubmed 出版商
Rodríguez Peña A, Grande M, Eleno N, Arevalo M, Guerrero C, Santos E, et al. Activation of Erk1/2 and Akt following unilateral ureteral obstruction. Kidney Int. 2008;74:196-209 pubmed 出版商
Golembieski W, Thomas S, Schultz C, Yunker C, McClung H, Lemke N, et al. HSP27 mediates SPARC-induced changes in glioma morphology, migration, and invasion. Glia. 2008;56:1061-75 pubmed 出版商
Kovanen P, Bernard J, Al Shami A, Liu C, Bollenbacher Reilley J, Young L, et al. T-cell development and function are modulated by dual specificity phosphatase DUSP5. J Biol Chem. 2008;283:17362-9 pubmed 出版商
Dougherty U, Sehdev A, Cerda S, Mustafi R, Little N, Yuan W, et al. Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model. Clin Cancer Res. 2008;14:2253-62 pubmed 出版商
Leboeuf R, Baumgartner J, Benezra M, Malaguarnera R, Solit D, Pratilas C, et al. BRAFV600E mutation is associated with preferential sensitivity to mitogen-activated protein kinase kinase inhibition in thyroid cancer cell lines. J Clin Endocrinol Metab. 2008;93:2194-201 pubmed 出版商
Dufour C, Holy X, Marie P. Transforming growth factor-beta prevents osteoblast apoptosis induced by skeletal unloading via PI3K/Akt, Bcl-2, and phospho-Bad signaling. Am J Physiol Endocrinol Metab. 2008;294:E794-801 pubmed 出版商
Guillaume J, Daulat A, Maurice P, Levoye A, Migaud M, Brydon L, et al. The PDZ protein mupp1 promotes Gi coupling and signaling of the Mt1 melatonin receptor. J Biol Chem. 2008;283:16762-71 pubmed 出版商
Xu D, Li H, Liu J. Inhibition of telomerase by targeting MAP kinase signaling. Methods Mol Biol. 2007;405:147-65 pubmed 出版商
Lapasset L, Pradet Balade B, Verge V, Lozano J, Oulhen N, Cormier P, et al. Cyclin B synthesis and rapamycin-sensitive regulation of protein synthesis during starfish oocyte meiotic divisions. Mol Reprod Dev. 2008;75:1617-26 pubmed 出版商
Kim J, Song G, Gao H, Farmer J, Satterfield M, Burghardt R, et al. Insulin-like growth factor II activates phosphatidylinositol 3-kinase-protooncogenic protein kinase 1 and mitogen-activated protein kinase cell Signaling pathways, and stimulates migration of ovine trophectoderm cells. Endocrinology. 2008;149:3085-94 pubmed 出版商
Lee D, Yeh C, Chang S, Lee P, Chien S, Cheng C, et al. Integrin-mediated expression of bone formation-related genes in osteoblast-like cells in response to fluid shear stress: roles of extracellular matrix, Shc, and mitogen-activated protein kinase. J Bone Miner Res. 2008;23:1140-9 pubmed 出版商
Bajova H, Nelson T, Gruol D. Chronic CXCL10 alters the level of activated ERK1/2 and transcriptional factors CREB and NF-kappaB in hippocampal neuronal cell culture. J Neuroimmunol. 2008;195:36-46 pubmed 出版商
Chen Y, Yu M, Podd A, Wen R, Chrzanowska Wodnicka M, White G, et al. A critical role of Rap1b in B-cell trafficking and marginal zone B-cell development. Blood. 2008;111:4627-36 pubmed 出版商
Pérez E, Machado J, Aliperti F, Freymuller E, Mariano M, Lopes J. B-1 lymphocytes increase metastatic behavior of melanoma cells through the extracellular signal-regulated kinase pathway. Cancer Sci. 2008;99:920-8 pubmed 出版商
Thiaville M, Pan Y, Gjymishka A, Zhong C, Kaufman R, Kilberg M. MEK signaling is required for phosphorylation of eIF2alpha following amino acid limitation of HepG2 human hepatoma cells. J Biol Chem. 2008;283:10848-57 pubmed 出版商
Konig H, Holtz M, Modi H, Manley P, Holyoake T, Forman S, et al. Enhanced BCR-ABL kinase inhibition does not result in increased inhibition of downstream signaling pathways or increased growth suppression in CML progenitors. Leukemia. 2008;22:748-55 pubmed 出版商
Marquez N, Calzado M, Sanchez Duffhues G, Perez M, Minassi A, Pagani A, et al. Differential effects of phorbol-13-monoesters on human immunodeficiency virus reactivation. Biochem Pharmacol. 2008;75:1370-80 pubmed 出版商
Toi S, Shibata N, Sawada T, Kobayashi M, Uchiyama S. Activation of the non-receptor tyrosine kinase cSrc in macrophage-rich atherosclerotic plaques of human carotid arteries. Acta Histochem Cytochem. 2007;40:153-61 pubmed 出版商
Kuznetsov A, Smigelskaite J, Doblander C, Janakiraman M, Hermann M, Wurm M, et al. Survival signaling by C-RAF: mitochondrial reactive oxygen species and Ca2+ are critical targets. Mol Cell Biol. 2008;28:2304-13 pubmed 出版商
Kim B, Chung H. Desferrioxamine (DFX) induces apoptosis through the p38-caspase8-Bid-Bax pathway in PHA-stimulated human lymphocytes. Toxicol Appl Pharmacol. 2008;228:24-31 pubmed 出版商
Sun W, Wang Q, Chen B, Liu J, Liu H, Xu W. Gamma-tocotrienol-induced apoptosis in human gastric cancer SGC-7901 cells is associated with a suppression in mitogen-activated protein kinase signalling. Br J Nutr. 2008;99:1247-54 pubmed
Kook S, Son Y, Jang Y, Lee K, Lee S, Kim B, et al. Inhibition of c-Jun N-terminal kinase sensitizes tumor cells to flavonoid-induced apoptosis through down-regulation of JunD. Toxicol Appl Pharmacol. 2008;227:468-76 pubmed
Konig H, Holyoake T, Bhatia R. Effective and selective inhibition of chronic myeloid leukemia primitive hematopoietic progenitors by the dual Src/Abl kinase inhibitor SKI-606. Blood. 2008;111:2329-38 pubmed
Kook S, Son Y, Choi K, Lee H, Chung W, Hwang I, et al. Cyclic mechanical stress suppresses myogenic differentiation of adult bovine satellite cells through activation of extracellular signal-regulated kinase. Mol Cell Biochem. 2008;309:133-41 pubmed
Kaizu T, Ikeda A, Nakao A, Tsung A, Toyokawa H, Ueki S, et al. Protection of transplant-induced hepatic ischemia/reperfusion injury with carbon monoxide via MEK/ERK1/2 pathway downregulation. Am J Physiol Gastrointest Liver Physiol. 2008;294:G236-44 pubmed
Pagano E, Coso O, Calvo J. Down-modulation of erbB2 activity is necessary but not enough in the differentiation of 3T3-L1 preadipocytes. J Cell Biochem. 2008;104:274-85 pubmed
Kleibeuker W, Jurado Pueyo M, Murga C, Eijkelkamp N, Mayor F, Heijnen C, et al. Physiological changes in GRK2 regulate CCL2-induced signaling to ERK1/2 and Akt but not to MEK1/2 and calcium. J Neurochem. 2008;104:979-92 pubmed
Watjen W, Kulawik A, Suckow Schnitker A, Chovolou Y, Rohrig R, Ruhl S, et al. Pterocarpans phaseollin and neorautenol isolated from Erythrina addisoniae induce apoptotic cell death accompanied by inhibition of ERK phosphorylation. Toxicology. 2007;242:71-9 pubmed
Peterziel H, Paech T, Strelau J, Unsicker K, Krieglstein K. Specificity in the crosstalk of TGFbeta/GDNF family members is determined by distinct GFR alpha receptors. J Neurochem. 2007;103:2491-504 pubmed
Magocsi M, Vizi E, Selmeczy Z, Brozik A, Szelenyi J. Multiple G-protein-coupling specificity of beta-adrenoceptor in macrophages. Immunology. 2007;122:503-13 pubmed
Nagao S, Nishii K, Yoshihara D, Kurahashi H, Nagaoka K, Yamashita T, et al. Calcium channel inhibition accelerates polycystic kidney disease progression in the Cy/+ rat. Kidney Int. 2008;73:269-77 pubmed
Quaglino A, Schere Levy C, Romorini L, Meiss R, Kordon E. Mouse mammary tumors display Stat3 activation dependent on leukemia inhibitory factor signaling. Breast Cancer Res. 2007;9:R69 pubmed
Zhang W, Yang J, Wang J, Xia P, Xu Y, Jia H, et al. Comparative studies on the increase of uterine weight and related mechanisms of cadmium and p-nonylphenol. Toxicology. 2007;241:84-91 pubmed
Feld M, Galli C, Piccini A, Romano A. Effect on memory of acute administration of naturally secreted fibrils and synthetic amyloid-beta peptides in an invertebrate model. Neurobiol Learn Mem. 2008;89:407-18 pubmed
Liu D, Liu Z, Jiang D, Dackiw A, Xing M. Inhibitory effects of the mitogen-activated protein kinase kinase inhibitor CI-1040 on the proliferation and tumor growth of thyroid cancer cells with BRAF or RAS mutations. J Clin Endocrinol Metab. 2007;92:4686-95 pubmed
Niu J, Li X, Qian H, Han Z. siRNA mediated the type 1 insulin-like growth factor receptor and epidermal growth factor receptor silencing induces chemosensitization of liver cancer cells. J Cancer Res Clin Oncol. 2008;134:503-13 pubmed
Nunez C, Laorden M, Milanes M. Regulation of serine (Ser)-31 and Ser40 tyrosine hydroxylase phosphorylation during morphine withdrawal in the hypothalamic paraventricular nucleus and nucleus tractus solitarius-A2 cell group: role of ERK1/2. Endocrinology. 2007;148:5780-93 pubmed
Chase A, Grand F, Cross N. Activity of TKI258 against primary cells and cell lines with FGFR1 fusion genes associated with the 8p11 myeloproliferative syndrome. Blood. 2007;110:3729-34 pubmed
Pandey J, Umphress S, Kang Y, Angdisen J, Naumova A, Mercer K, et al. Modulation of tumor induction and progression of oncogenic K-ras-positive tumors in the presence of TGF- b1 haploinsufficiency. Carcinogenesis. 2007;28:2589-96 pubmed
Fuhrman B, Nitzan O, Karry R, Volkova N, Dumler I, Aviram M. Urokinase plasminogen activator (uPA) stimulates cholesterol biosynthesis in macrophages through activation of SREBP-1 in a PI3-kinase and MEK-dependent manner. Atherosclerosis. 2007;195:e108-16 pubmed
Kukushkin A, Svetlikova S, Amanzholov R, Pospelov V. Anisomycin abrogates repression of protooncogene c-fos transcription in E1A + cHa-ras-transformed cells through activation of MEK/ERK kinase cascade. J Cell Biochem. 2008;103:1005-12 pubmed
Bozzo F, Bocca C, Colombatto S, Miglietta A. Antiproliferative effect of conjugated linoleic acid in caco-2 cells: involvement of PPARgamma and APC/beta-catenin pathways. Chem Biol Interact. 2007;169:110-21 pubmed
Skelly C, Chandiwal A, Vosicky J, Weichselbaum R, Roizman B. Attenuated herpes simplex virus 1 blocks arterial apoptosis and intimal hyperplasia induced by balloon angioplasty and reduced blood flow. Proc Natl Acad Sci U S A. 2007;104:12474-8 pubmed
Cohen E, Wang Z, Lepore J, Lu M, Taketo M, Epstein D, et al. Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling. J Clin Invest. 2007;117:1794-804 pubmed
Lee K, Song K. Actin dysfunction activates ERK1/2 and delays entry into mitosis in mammalian cells. Cell Cycle. 2007;6:1487-95 pubmed
Fichera A, Little N, Dougherty U, Mustafi R, Cerda S, Li Y, et al. A vitamin D analogue inhibits colonic carcinogenesis in the AOM/DSS model. J Surg Res. 2007;142:239-45 pubmed
Al Salihi M, Ulmer S, Doan T, Nelson C, Crotty T, Prescott S, et al. Cyclooxygenase-2 transactivates the epidermal growth factor receptor through specific E-prostanoid receptors and tumor necrosis factor-alpha converting enzyme. Cell Signal. 2007;19:1956-63 pubmed
McLaren J, Rowe M, Brennan P. Epstein-Barr virus induces a distinct form of DNA-bound STAT1 compared with that found in interferon-stimulated B lymphocytes. J Gen Virol. 2007;88:1876-86 pubmed
Almela P, Milanes M, Laorden M. Activation of the ERK signalling pathway contributes to the adaptive changes in rat hearts during naloxone-induced morphine withdrawal. Br J Pharmacol. 2007;151:787-97 pubmed
Yamaguchi T, Arai H, Katayama N, Ishikawa T, Kikumoto K, Atomi Y. Age-related increase of insoluble, phosphorylated small heat shock proteins in human skeletal muscle. J Gerontol A Biol Sci Med Sci. 2007;62:481-9 pubmed
Wu J, Jin Y, Calaf G, Huang W, Yin Y. PAC1 is a direct transcription target of E2F-1 in apoptotic signaling. Oncogene. 2007;26:6526-35 pubmed
Lotti L, Rotolo S, Francescangeli F, Frati L, Torrisi M, Marchese C. AKT and MAPK signaling in KGF-treated and UVB-exposed human epidermal cells. J Cell Physiol. 2007;212:633-42 pubmed
Furmaniak Kazmierczak E, Crawley S, Carter R, Maurice D, Côté G. Formation of extracellular matrix-digesting invadopodia by primary aortic smooth muscle cells. Circ Res. 2007;100:1328-36 pubmed
Sei Y, Ren Patterson R, Li Z, Tunbridge E, Egan M, Kolachana B, et al. Neuregulin1-induced cell migration is impaired in schizophrenia: association with neuregulin1 and catechol-o-methyltransferase gene polymorphisms. Mol Psychiatry. 2007;12:946-57 pubmed
Ericsson C, Peredo I, Nister M. Optimized protein extraction from cryopreserved brain tissue samples. Acta Oncol. 2007;46:10-20 pubmed
Lombardi M, Vroon A, Sodaar P, van Muiswinkel F, Heijnen C, Kavelaars A. Down-regulation of GRK2 after oxygen and glucose deprivation in rat hippocampal slices: role of the PI3-kinase pathway. J Neurochem. 2007;102:731-40 pubmed
Fan M, Ahmed K, Coleman M, Spitz D, Li J. Nuclear factor-kappaB and manganese superoxide dismutase mediate adaptive radioresistance in low-dose irradiated mouse skin epithelial cells. Cancer Res. 2007;67:3220-8 pubmed
Lee J, Kim H, Hahm K, Sohn M, Yoo M, Johnson J, et al. Inhibitory effects of 7-carboxymethyloxy-3',4',5-trimethoxyflavone (DA-6034) on Helicobacter pylori-induced NF-kappa B activation and iNOS expression in AGS cells. Ann N Y Acad Sci. 2007;1095:527-35 pubmed
Jung J, Hwang S, Hwang J, Oh E, Park S, Han I. Ionising radiation induces changes associated with epithelial-mesenchymal transdifferentiation and increased cell motility of A549 lung epithelial cells. Eur J Cancer. 2007;43:1214-24 pubmed
Liu D, Liu Z, Condouris S, Xing M. BRAF V600E maintains proliferation, transformation, and tumorigenicity of BRAF-mutant papillary thyroid cancer cells. J Clin Endocrinol Metab. 2007;92:2264-71 pubmed
Chiu J, Chen L, Lee C, Lee P, Lee D, Tsai M, et al. Mechanisms of induction of endothelial cell E-selectin expression by smooth muscle cells and its inhibition by shear stress. Blood. 2007;110:519-28 pubmed
Modi H, McDonald T, Chu S, Yee J, Forman S, Bhatia R. Role of BCR/ABL gene-expression levels in determining the phenotype and imatinib sensitivity of transformed human hematopoietic cells. Blood. 2007;109:5411-21 pubmed
Yang S, Li Z, Jin L, Song B, Liu G, Chen J, et al. Synthesis and bioactivity of 4-alkyl(aryl)thioquinazoline derivatives. Bioorg Med Chem Lett. 2007;17:2193-6 pubmed
Martins I, Deshayes F, Baton F, Forget A, Ciechomska I, Sylla K, et al. Pathologic expression of MHC class II is driven by mitogen-activated protein kinases. Eur J Immunol. 2007;37:788-97 pubmed
Garcia Garcia E, Rosales C. Nuclear factor activation by FcgammaR in human peripheral blood neutrophils detected by a novel flow cytometry-based method. J Immunol Methods. 2007;320:104-18 pubmed
Alagbala A, Johnson C, Trump D, Posner G, Foster B. Antitumor effects of two less-calcemic vitamin D analogs (Paricalcitol and QW-1624F2-2) in squamous cell carcinoma cells. Oncology. 2006;70:483-92 pubmed
Flynn G, Chung I, Yu W, Romano M, Modzelewski R, Johnson C, et al. Calcitriol (1,25-dihydroxycholecalciferol) selectively inhibits proliferation of freshly isolated tumor-derived endothelial cells and induces apoptosis. Oncology. 2006;70:447-57 pubmed
Rajput A, Koterba A, Kreisberg J, Foster J, Willson J, Brattain M. A novel mechanism of resistance to epidermal growth factor receptor antagonism in vivo. Cancer Res. 2007;67:665-73 pubmed
Recktenwald C, Mendler S, Lichtenfels R, Kellner R, Seliger B. Influence of Ki-ras-driven oncogenic transformation on the protein network of murine fibroblasts. Proteomics. 2007;7:385-98 pubmed
Sherry C, O Connor J, Kramer J, Freund G. Augmented lipopolysaccharide-induced TNF-alpha production by peritoneal macrophages in type 2 diabetic mice is dependent on elevated glucose and requires p38 MAPK. J Immunol. 2007;178:663-70 pubmed
Caballero F, Navarrete C, Hess S, Fiebich B, Appendino G, Macho A, et al. The acetaminophen-derived bioactive N-acylphenolamine AM404 inhibits NFAT by targeting nuclear regulatory events. Biochem Pharmacol. 2007;73:1013-23 pubmed
Chen Y, Pappu B, Zeng H, Xue L, Morris S, Lin X, et al. B cell lymphoma 10 is essential for FcepsilonR-mediated degranulation and IL-6 production in mast cells. J Immunol. 2007;178:49-57 pubmed
Dufour C, Holy X, Marie P. Skeletal unloading induces osteoblast apoptosis and targets alpha5beta1-PI3K-Bcl-2 signaling in rat bone. Exp Cell Res. 2007;313:394-403 pubmed
Malmlöf M, Roudier E, Hogberg J, Stenius U. MEK-ERK-mediated phosphorylation of Mdm2 at Ser-166 in hepatocytes. Mdm2 is activated in response to inhibited Akt signaling. J Biol Chem. 2007;282:2288-96 pubmed
Lourda M, Trougakos I, Gonos E. Development of resistance to chemotherapeutic drugs in human osteosarcoma cell lines largely depends on up-regulation of Clusterin/Apolipoprotein J. Int J Cancer. 2007;120:611-22 pubmed
Tanabe Y, Morikawa Y, Kato T, Kanai S, Watakabe T, Nishijima A, et al. Effects of olmesartan, an AT1 receptor antagonist, on hypoxia-induced activation of ERK1/2 and pro-inflammatory signals in the mouse lung. Naunyn Schmiedebergs Arch Pharmacol. 2006;374:235-48 pubmed
Cho D, Lee H, Kim H, Hong S, Pyo J, Cho C, et al. Suppression of hypoxic cell death by APIP-induced sustained activation of AKT and ERK1/2. Oncogene. 2007;26:2809-14 pubmed
LaChapelle A, Ruygrok M, Toomer M, Oost J, Monnie M, Swenson J, et al. The hormonal herbicide, 2,4-dichlorophenoxyacetic acid, inhibits Xenopus oocyte maturation by targeting translational and post-translational mechanisms. Reprod Toxicol. 2007;23:20-31 pubmed
Fu J, Ding Y, Huang D, Li H, Chen X. The retinoid X receptor-selective ligand, LGD1069, inhibits tumor-induced angiogenesis via suppression of VEGF in human non-small cell lung cancer. Cancer Lett. 2007;248:153-63 pubmed
Bocca C, Bozzo F, Gabriel L, Miglietta A. Conjugated linoleic acid inhibits Caco-2 cell growth via ERK-MAPK signaling pathway. J Nutr Biochem. 2007;18:332-40 pubmed
Wei L, Sun X, Kanbe K, Wang Z, Sun C, Terek R, et al. Chondrocyte death induced by pathological concentration of chemokine stromal cell-derived factor-1. J Rheumatol. 2006;33:1818-26 pubmed
Yuki T, Ishihara S, Rumi M, Ortega Cava C, Kadowaki Y, Kazumori H, et al. Increased expression of midkine in the rat colon during healing of experimental colitis. Am J Physiol Gastrointest Liver Physiol. 2006;291:G735-43 pubmed
Smith L, Watson M, O Kane S, Drew P, Lind M, Cawkwell L. The analysis of doxorubicin resistance in human breast cancer cells using antibody microarrays. Mol Cancer Ther. 2006;5:2115-20 pubmed
Ma Y, Yu W, Kong R, Trump D, Johnson C. Role of nongenomic activation of phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase/extracellular signal-regulated kinase kinase/extracellular signal-regulated kinase 1/2 pathways in 1,25D3-mediated apoptosis in squamous cell carc. Cancer Res. 2006;66:8131-8 pubmed
Kohmoto J, Nakao A, Kaizu T, Tsung A, Ikeda A, Tomiyama K, et al. Low-dose carbon monoxide inhalation prevents ischemia/reperfusion injury of transplanted rat lung grafts. Surgery. 2006;140:179-85 pubmed
Russ D, Lovering R. Influence of activation frequency on cellular signalling pathways during fatiguing contractions in rat skeletal muscle. Exp Physiol. 2006;91:957-66 pubmed
Navarrete C, Sancho R, Caballero F, Pollastro F, Fiebich B, Sterner O, et al. Basiliolides, a class of tetracyclic C19 dilactones from Thapsia garganica, release Ca(2+) from the endoplasmic reticulum and regulate the activity of the transcription factors nuclear factor of activated T cells, nuclear factor-kappaB, and activator. J Pharmacol Exp Ther. 2006;319:422-30 pubmed
Ueda S, Tsuda H, Sato K, Takeuchi H, Shigekawa T, Matsubara O, et al. Alternative tyrosine phosphorylation of signaling kinases according to hormone receptor status in breast cancer overexpressing the insulin-like growth factor receptor type 1. Cancer Sci. 2006;97:597-604 pubmed
Nagao S, Nishii K, Katsuyama M, Kurahashi H, Marunouchi T, Takahashi H, et al. Increased water intake decreases progression of polycystic kidney disease in the PCK rat. J Am Soc Nephrol. 2006;17:2220-7 pubmed
Nielsen E, Eskildsen Helmond Y, Rattan S. MAP kinases and heat shock-induced hormesis in human fibroblasts during serial passaging in vitro. Ann N Y Acad Sci. 2006;1067:343-8 pubmed
Hahn C, Wang H, Cho D, Talbot K, Gur R, Berrettini W, et al. Altered neuregulin 1-erbB4 signaling contributes to NMDA receptor hypofunction in schizophrenia. Nat Med. 2006;12:824-8 pubmed
Relic B, Benoit V, Franchimont N, Kaiser M, Hauzeur J, Gillet P, et al. Peroxisome proliferator-activated receptor-gamma1 is dephosphorylated and degraded during BAY 11-7085-induced synovial fibroblast apoptosis. J Biol Chem. 2006;281:22597-604 pubmed
Son S, Yu E, Ahn Y, Choi E, Lee H, Choi J. Retinoic acid attenuates promyelocytic leukemia protein-induced cell death in breast cancer cells by activation of the ubiquitin-proteasome pathway. Cancer Lett. 2007;247:213-23 pubmed
Rhoads J, Niu X, Odle J, Graves L. Role of mTOR signaling in intestinal cell migration. Am J Physiol Gastrointest Liver Physiol. 2006;291:G510-7 pubmed
Kang M, Seo J, Park W. Caveolin-1 inhibits neurite growth by blocking Rac1/Cdc42 and p21-activated kinase 1 interactions. Neuroreport. 2006;17:823-7 pubmed
Badrian B, Casey T, Lai M, Rakoczy P, Arthur P, Bogoyevitch M. Contrasting actions of prolonged mitogen-activated protein kinase activation on cell survival. Biochem Biophys Res Commun. 2006;345:843-50 pubmed
Dekanty A, Giulianelli S, Coso O, Rudland P, Jimenez de Asua L. Differential involvement of ERK1-2 and p38MAPK activation on Swiss 3T3 cell proliferation induced by prostaglandin F2alpha. FEBS Lett. 2006;580:2512-6 pubmed
Moiseeva E, Fox L, Howells L, Temple L, Manson M. Indole-3-carbinol-induced death in cancer cells involves EGFR downregulation and is exacerbated in a 3D environment. Apoptosis. 2006;11:799-812 pubmed
Yamauchi T, Sawa Y, Sakurai M, Hiroshi T, Matsumiya G, Abe K, et al. ONO-5046 attenuation of delayed motor neuron death and effect on the induction of brain-derived neurotrophic factor, phosphorylated extracellular signal-regulated kinase, and caspase3 after spinal cord ischemia in rabbits. J Thorac Cardiovasc Surg. 2006;131:644-50 pubmed
Nakuci E, Xu M, Pujana M, Valls J, ElShamy W. Geminin is bound to chromatin in G2/M phase to promote proper cytokinesis. Int J Biochem Cell Biol. 2006;38:1207-20 pubmed
Yu X, Luo A, Zhou C, Ding F, Wu M, Zhan Q, et al. Differentiation-associated genes regulated by TPA-induced c-Jun expression via a PKC/JNK pathway in KYSE450 cells. Biochem Biophys Res Commun. 2006;342:286-92 pubmed
Peng L, Jin G, Wang L, Guo J, Meng L, Shou C. Identification of integrin alpha1 as an interacting protein of protein tyrosine phosphatase PRL-3. Biochem Biophys Res Commun. 2006;342:179-83 pubmed
Dolci S, Belmonte A, Santone R, Giorgi M, Pellegrini M, Carosa E, et al. Subcellular localization and regulation of type-1C and type-5 phosphodiesterases. Biochem Biophys Res Commun. 2006;341:837-46 pubmed
Li X, Zhang S, Safe S. Activation of kinase pathways in MCF-7 cells by 17beta-estradiol and structurally diverse estrogenic compounds. J Steroid Biochem Mol Biol. 2006;98:122-32 pubmed
Li X, Campbell D, Ohishi M, Yuan S, Zhuo J. AT1 receptor-activated signaling mediates angiotensin IV-induced renal cortical vasoconstriction in rats. Am J Physiol Renal Physiol. 2006;290:F1024-33 pubmed
Bundy L, Wells S, Sealy L. C/EBPbeta-2 confers EGF-independent growth and disrupts the normal acinar architecture of human mammary epithelial cells. Mol Cancer. 2005;4:43 pubmed
Behren A, Simon C, Schwab R, Loetzsch E, Brodbeck S, Huber E, et al. Papillomavirus E2 protein induces expression of the matrix metalloproteinase-9 via the extracellular signal-regulated kinase/activator protein-1 signaling pathway. Cancer Res. 2005;65:11613-21 pubmed
Bryja V, Bonilla S, Cajanek L, Parish C, Schwartz C, Luo Y, et al. An efficient method for the derivation of mouse embryonic stem cells. Stem Cells. 2006;24:844-9 pubmed
Papachristou D, Papachristou G, Papachristou G, Papaefthimiou O, Agnantis N, Basdra E, et al. The MAPK-AP-1/-Runx2 signalling axes are implicated in chondrosarcoma pathobiology either independently or via up-regulation of VEGF. Histopathology. 2005;47:565-74 pubmed
Lien S, Usami S, Chien S, Chiu J. Phosphatidylinositol 3-kinase/Akt pathway is involved in transforming growth factor-beta1-induced phenotypic modulation of 10T1/2 cells to smooth muscle cells. Cell Signal. 2006;18:1270-8 pubmed
Lee K, Im J, Song J, Lee S, Lee H, Ha H, et al. Progressive neuronal loss and behavioral impairments of transgenic C57BL/6 inbred mice expressing the carboxy terminus of amyloid precursor protein. Neurobiol Dis. 2006;22:10-24 pubmed
Botolin D, Wang Y, Christian B, Jump D. Docosahexaneoic acid (22:6,n-3) regulates rat hepatocyte SREBP-1 nuclear abundance by Erk- and 26S proteasome-dependent pathways. J Lipid Res. 2006;47:181-92 pubmed
Fischer D, Hol E, Hobo B, van Leeuwen F. Alzheimer-associated APP+1 transgenic mice: frameshift beta-amyloid precursor protein is secreted in cerebrospinal fluid without inducing neuropathology. Neurobiol Aging. 2006;27:1445-50 pubmed
Bento L, Carvalheira J, Menegon L, Saad M, Gontijo J. Effects of NH4Cl intake on renal growth in rats: role of MAPK signalling pathway. Nephrol Dial Transplant. 2005;20:2654-60 pubmed
Roberts M, Drosopoulos K, Vasileiou I, Stricker M, Taoufik E, Maercker C, et al. Microarray analysis of the differential transformation mediated by Kirsten and Harvey Ras oncogenes in a human colorectal adenocarcinoma cell line. Int J Cancer. 2006;118:616-27 pubmed
Lapasset L, Pradet Balade B, Lozano J, Peaucellier G, Picard A. Nuclear envelope breakdown may deliver an inhibitor of protein phosphatase 1 which triggers cyclin B translation in starfish oocytes. Dev Biol. 2005;285:200-10 pubmed
Papachristou D, Pirttiniemi P, Kantomaa T, Papavassiliou A, Basdra E. JNK/ERK-AP-1/Runx2 induction "paves the way" to cartilage load-ignited chondroblastic differentiation. Histochem Cell Biol. 2005;124:215-23 pubmed
Lin L, Stringfield T, Shi X, Chen Y. Arsenite induces a cell stress-response gene, RTP801, through reactive oxygen species and transcription factors Elk-1 and CCAAT/enhancer-binding protein. Biochem J. 2005;392:93-102 pubmed
Chung Y, Joo K, Lim H, Cho M, Kim D, Lee W, et al. Immunohistochemical study on the distribution of phosphorylated extracellular signal-regulated kinase (ERK) in the central nervous system of SOD1G93A transgenic mice. Brain Res. 2005;1050:203-9 pubmed
Ahmed Choudhury J, Williams K, Young L, Adams D, Afford S. CD40 mediated human cholangiocyte apoptosis requires JAK2 dependent activation of STAT3 in addition to activation of JNK1/2 and ERK1/2. Cell Signal. 2006;18:456-68 pubmed
Nadruz W, Corat M, Marin T, Guimarães Pereira G, Franchini K. Focal adhesion kinase mediates MEF2 and c-Jun activation by stretch: role in the activation of the cardiac hypertrophic genetic program. Cardiovasc Res. 2005;68:87-97 pubmed
Dvorak P, Dvorakova D, Koskova S, Vodinska M, Najvirtova M, Krekac D, et al. Expression and potential role of fibroblast growth factor 2 and its receptors in human embryonic stem cells. Stem Cells. 2005;23:1200-11 pubmed
Chen L, Wang P, Andrade C, Zhao I, Dubé P, Brubaker P, et al. PKA independent and cell type specific activation of the expression of caudal homeobox gene Cdx-2 by cyclic AMP. FEBS J. 2005;272:2746-59 pubmed
Vega L, Munoz E, Calzado M, Lieb K, Candelario Jalil E, Gschaidmeir H, et al. The 5-HT3 receptor antagonist tropisetron inhibits T cell activation by targeting the calcineurin pathway. Biochem Pharmacol. 2005;70:369-80 pubmed
Nagao S, Kusaka M, Nishii K, Marunouchi T, Kurahashi H, Takahashi H, et al. Androgen receptor pathway in rats with autosomal dominant polycystic kidney disease. J Am Soc Nephrol. 2005;16:2052-62 pubmed
Kim Y, Kim S, Cho J, Choi D, Hwang O, Shin D, et al. Matrix metalloproteinase-3: a novel signaling proteinase from apoptotic neuronal cells that activates microglia. J Neurosci. 2005;25:3701-11 pubmed
Ishibe T, Nakayama T, Okamoto T, Aoyama T, Nishijo K, Shibata K, et al. Disruption of fibroblast growth factor signal pathway inhibits the growth of synovial sarcomas: potential application of signal inhibitors to molecular target therapy. Clin Cancer Res. 2005;11:2702-12 pubmed
Lesne S, Gabriel C, Nelson D, White E, Mackenzie E, Vivien D, et al. Akt-dependent expression of NAIP-1 protects neurons against amyloid-{beta} toxicity. J Biol Chem. 2005;280:24941-7 pubmed
Drosopoulos K, Roberts M, Cermak L, Sasazuki T, Shirasawa S, Andera L, et al. Transformation by oncogenic RAS sensitizes human colon cells to TRAIL-induced apoptosis by up-regulating death receptor 4 and death receptor 5 through a MEK-dependent pathway. J Biol Chem. 2005;280:22856-67 pubmed
Jimenez E, Montiel M. Activation of MAP kinase by muscarinic cholinergic receptors induces cell proliferation and protein synthesis in human breast cancer cells. J Cell Physiol. 2005;204:678-86 pubmed
Caron R, Yacoub A, Zhu X, Mitchell C, Han S, Sasazuki T, et al. H-RAS V12-induced radioresistance in HCT116 colon carcinoma cells is heregulin dependent. Mol Cancer Ther. 2005;4:243-55 pubmed
Chen H, Kovar J, Sissons S, Cox K, Matter W, Chadwell F, et al. A cell-based immunocytochemical assay for monitoring kinase signaling pathways and drug efficacy. Anal Biochem. 2005;338:136-42 pubmed
Feld M, Dimant B, Delorenzi A, Coso O, Romano A. Phosphorylation of extra-nuclear ERK/MAPK is required for long-term memory consolidation in the crab Chasmagnathus. Behav Brain Res. 2005;158:251-61 pubmed
Yang T, Xiong Q, Graef I, Crabtree G, Chow C. Recruitment of the extracellular signal-regulated kinase/ribosomal S6 kinase signaling pathway to the NFATc4 transcription activation complex. Mol Cell Biol. 2005;25:907-20 pubmed
Caron R, Yacoub A, Mitchell C, Zhu X, Hong Y, Sasazuki T, et al. Radiation-stimulated ERK1/2 and JNK1/2 signaling can promote cell cycle progression in human colon cancer cells. Cell Cycle. 2005;4:456-64 pubmed
Samarakoon R, Higgins C, Higgins S, Kutz S, Higgins P. Plasminogen activator inhibitor type-1 gene expression and induced migration in TGF-beta1-stimulated smooth muscle cells is pp60(c-src)/MEK-dependent. J Cell Physiol. 2005;204:236-46 pubmed
Simon M, Vanes L, Geahlen R, Tybulewicz V. Distinct roles for the linker region tyrosines of Syk in FcepsilonRI signaling in primary mast cells. J Biol Chem. 2005;280:4510-7 pubmed
Datta B, Datta R, Majumdar A, Ghosh A. The stability of eukaryotic initiation factor 2-associated glycoprotein, p67, increases during skeletal muscle differentiation and that inhibits the phosphorylation of extracellular signal-regulated kinases 1 and 2. Exp Cell Res. 2005;303:174-82 pubmed
Ottonello L, Montecucco F, Bertolotto M, Arduino N, Mancini M, Corcione A, et al. CCL3 (MIP-1alpha) induces in vitro migration of GM-CSF-primed human neutrophils via CCR5-dependent activation of ERK 1/2. Cell Signal. 2005;17:355-63 pubmed
Shen C, Tsimberg Y, Salvadore C, Meller E. Activation of Erk and JNK MAPK pathways by acute swim stress in rat brain regions. BMC Neurosci. 2004;5:36 pubmed
产品信息
产品名称 :
p-ERK(E-4)抗体
基因名称 :
MAPK3, MAPK1
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-7383
修饰 :
phosporylated
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
p-ERK
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), 酶联免疫吸附测定
表位 :
Tyr 204 (h)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。