产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
磷酸酶张力蛋白同源基因(A2B1)抗体
目录 :
sc-7974
规格 :
200微克/毫升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
A2b1
反应物种 :
人类, 小鼠, 大鼠,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 99
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 1:300; 图 7f
  • 免疫印迹; 小鼠; 1:2500; 图 4a, 7g
  • 免疫组化-石蜡切片; 人类; 1:300; 图 8f
  • 免疫印迹; 人类; 1:2500; 图 6a, 6b, 6c, 8k
Xia R, Liu T, Li W, Xu X. RNA-binding protein RBM24 represses colorectal tumourigenesis by stabilising PTEN mRNA. Clin Transl Med. 2021;11:e383 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 7d
Loureiro J, Raimundo L, Calheiros J, Carvalho C, Barcherini V, Lima N, et al. Targeting p53 for Melanoma Treatment: Counteracting Tumour Proliferation, Dissemination and Therapeutic Resistance. Cancers (Basel). 2021;13: pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 3
Li J, Zhang W, Zhu S, Shi F. Nitric Oxide Synthase Is Involved in Follicular Development via the PI3K/AKT/FoxO3a Pathway in Neonatal and Immature Rats. Animals (Basel). 2020;10: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7a
Li R, Sahu S, Schachner M. Phenelzine, a small organic compound mimicking the functions of cell adhesion molecule L1, promotes functional recovery after mouse spinal cord injury. Restor Neurol Neurosci. 2018;36:469-483 pubmed 出版商
  • 免疫沉淀; 人类; 图 4d
Gupta A, Anjomani Virmouni S, Koundouros N, Dimitriadi M, Choo Wing R, Valle A, et al. PARK2 Depletion Connects Energy and Oxidative Stress to PI3K/Akt Activation via PTEN S-Nitrosylation. Mol Cell. 2017;65:999-1013.e7 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 6a
Visuttijai K, Pettersson J, Mehrbani Azar Y, van den Bout I, Orndal C, Marcickiewicz J, et al. Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT. PLoS ONE. 2016;11:e0164063 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 7
Song C, Liu B, Shi Y, Liu N, Yan Y, Zhang J, et al. MicroRNA-130a alleviates human coronary artery endothelial cell injury and inflammatory responses by targeting PTEN via activating PI3K/Akt/eNOS signaling pathway. Oncotarget. 2016;7:71922-71936 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s7
Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 s3
Zhong W, Yi Q, Xu B, Li S, Wang T, Liu F, et al. ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival. Nat Commun. 2016;7:12702 pubmed 出版商
  • 免疫印迹; 人类; 图 4D
Georgescu M, Gagea M, Cote G. NHERF1/EBP50 Suppresses Wnt-?-Catenin Pathway-Driven Intestinal Neoplasia. Neoplasia. 2016;18:512-23 pubmed 出版商
  • 免疫印迹; 人类; 图 5b
Kemper K, Krijgsman O, Kong X, Cornelissen Steijger P, Shahrabi A, Weeber F, et al. BRAF(V600E) Kinase Domain Duplication Identified in Therapy-Refractory Melanoma Patient-Derived Xenografts. Cell Rep. 2016;16:263-277 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Hendrayani S, Al Harbi B, Al Ansari M, Silva G, Aboussekhra A. The inflammatory/cancer-related IL-6/STAT3/NF-?B positive feedback loop includes AUF1 and maintains the active state of breast myofibroblasts. Oncotarget. 2016;7:41974-41985 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Yang E, Ahn S, Lee K, Mahmood U, Kim H. Early Behavioral Abnormalities and Perinatal Alterations of PTEN/AKT Pathway in Valproic Acid Autism Model Mice. PLoS ONE. 2016;11:e0153298 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50
Missiroli S, Morganti C, Giorgi C, Pinton P. Methods to Study PTEN in Mitochondria and Endoplasmic Reticulum. Methods Mol Biol. 2016;1388:187-212 pubmed 出版商
  • 免疫印迹; 犬; 1:1000; 图 5A
Domínguez Calderón A, Ávila Flores A, Ponce A, López Bayghen E, Calderón Salinas J, Luis Reyes J, et al. ZO-2 silencing induces renal hypertrophy through a cell cycle mechanism and the activation of YAP and the mTOR pathway. Mol Biol Cell. 2016;27:1581-95 pubmed 出版商
  • 免疫印迹; 人类; 图 4b
Hung M, Chen Y, Chu P, Shih C, Yu H, Tai W, et al. Upregulation of the oncoprotein SET determines poor clinical outcomes in hepatocellular carcinoma and shows therapeutic potential. Oncogene. 2016;35:4891-902 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Yoshida T, Song L, Bai Y, Kinose F, Li J, Ohaegbulam K, et al. ZEB1 Mediates Acquired Resistance to the Epidermal Growth Factor Receptor-Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer. PLoS ONE. 2016;11:e0147344 pubmed 出版商
  • 免疫沉淀; 人类; 图 2b
  • 免疫印迹; 人类; 图 2b
  • 免疫沉淀; 小鼠; 图 2b
  • 免疫印迹; 小鼠; 图 2b
Kang X, Song C, Du X, Zhang C, Liu Y, Liang L, et al. PTEN stabilizes TOP2A and regulates the DNA decatenation. Sci Rep. 2015;5:17873 pubmed 出版商
  • 免疫印迹; 小鼠; 图 8
Hukelmann J, Anderson K, Sinclair L, Grzes K, Murillo A, Hawkins P, et al. The cytotoxic T cell proteome and its shaping by the kinase mTOR. Nat Immunol. 2016;17:104-12 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 1:500; 图 5
Lauková J, Kozubík A, Hofmanová J, Nekvindová J, Sova P, Moyer M, et al. Loss of PTEN Facilitates Rosiglitazone-Mediated Enhancement of Platinum(IV) Complex LA-12-Induced Apoptosis in Colon Cancer Cells. PLoS ONE. 2015;10:e0141020 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1b
Lee M, Jeong M, Lee H, Han H, Ko A, Hewitt S, et al. PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis. Nat Commun. 2015;6:7769 pubmed 出版商
  • 免疫印迹; 人类; 图 1d
Cao X, Kaneko T, Li J, Liu A, Voss C, Li S. A phosphorylation switch controls the spatiotemporal activation of Rho GTPases in directional cell migration. Nat Commun. 2015;6:7721 pubmed 出版商
  • 免疫印迹; 小鼠
Albers J, Danzer C, Rechsteiner M, Lehmann H, Brandt L, Hejhal T, et al. A versatile modular vector system for rapid combinatorial mammalian genetics. J Clin Invest. 2015;125:1603-19 pubmed 出版商
  • 免疫印迹; 人类
Majuelos Melguizo J, Rodríguez M, López Jiménez L, Rodríguez Vargas J, Martí Martín Consuegra J, Serrano Sáenz S, et al. PARP targeting counteracts gliomagenesis through induction of mitotic catastrophe and aggravation of deficiency in homologous recombination in PTEN-mutant glioma. Oncotarget. 2015;6:4790-803 pubmed
  • 免疫组化; 小鼠; 1:200
  • 免疫印迹; 小鼠; 1:500
Grande V, Manassero G, Vercelli A. Neuroprotective and anti-inflammatory roles of the phosphatase and tensin homolog deleted on chromosome Ten (PTEN) Inhibition in a Mouse Model of Temporal Lobe Epilepsy. PLoS ONE. 2014;9:e114554 pubmed 出版商
  • 免疫组化; 小鼠; 图 3
LITTLE D, Valori C, Mutsaers C, Bennett E, Wyles M, Sharrack B, et al. PTEN depletion decreases disease severity and modestly prolongs survival in a mouse model of spinal muscular atrophy. Mol Ther. 2015;23:270-7 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Balbas M, Burgess M, Murali R, Wongvipat J, Skaggs B, Mundel P, et al. MAGI-2 scaffold protein is critical for kidney barrier function. Proc Natl Acad Sci U S A. 2014;111:14876-81 pubmed 出版商
  • 免疫印迹; 人类
Bailon E, Ugarte Berzal E, Amigo Jiménez I, Van den Steen P, Opdenakker G, Garcia Marco J, et al. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen. J Leukoc Biol. 2014;96:185-99 pubmed 出版商
  • 免疫印迹; 人类
Jung S, Ohk J, Jeong D, Li C, Lee S, Duan J, et al. Distinct regulatory effect of the p34SEI-1 oncoprotein on cancer metastasis in HER2/neu-positive and -negative cells. Int J Oncol. 2014;45:189-96 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Ma J, Liu J, Wang Z, Gu X, Fan Y, Zhang W, et al. NF-kappaB-dependent microRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1? induction. Mol Cancer. 2014;13:40 pubmed 出版商
  • 免疫印迹; 人类; 1:200
Miyazawa N, Yoshikawa H, Magae S, Ishikawa H, Izumikawa K, Terukina G, et al. Human cell growth regulator Ly-1 antibody reactive homologue accelerates processing of preribosomal RNA. Genes Cells. 2014;19:273-86 pubmed 出版商
  • 免疫印迹; 人类
Liu X, Chen L, Feng B, Liu G. Reversing effect of sorcin in the drug resistance of human nasopharyngeal carcinoma. Anat Rec (Hoboken). 2014;297:215-21 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Fernandez S, Genis L, Torres Aleman I. A phosphatase-independent gain-of-function mutation in PTEN triggers aberrant cell growth in astrocytes through an autocrine IGF-1 loop. Oncogene. 2014;33:4114-22 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Pérez Sieira S, Martinez G, Porteiro B, Lopez M, Vidal A, Nogueiras R, et al. Female Nur77-deficient mice show increased susceptibility to diet-induced obesity. PLoS ONE. 2013;8:e53836 pubmed 出版商
Coronel Hernández J, López Urrutia E, Contreras Romero C, Delgado Waldo I, Figueroa González G, Campos Parra A, et al. Cell migration and proliferation are regulated by miR-26a in colorectal cancer via the PTEN-AKT axis. Cancer Cell Int. 2019;19:80 pubmed 出版商
Chai C, Wu H, Wang B, Eisenstat D, Leng R. MicroRNA-498 promotes proliferation and migration by targeting the tumor suppressor PTEN in breast cancer cells. Carcinogenesis. 2018;39:1185-1196 pubmed 出版商
Dong P, Xiong Y, Yu J, Chen L, Tao T, Yi S, et al. Control of PD-L1 expression by miR-140/142/340/383 and oncogenic activation of the OCT4-miR-18a pathway in cervical cancer. Oncogene. 2018;37:5257-5268 pubmed 出版商
Brandt L, Albers J, Hejhal T, Pfundstein S, Gonçalves A, Catalano A, et al. Mouse genetic background influences whether HrasG12V expression plus Cdkn2a knockdown causes angiosarcoma or undifferentiated pleomorphic sarcoma. Oncotarget. 2018;9:19753-19766 pubmed 出版商
Wang J, Ye Q, Cao Y, Guo Y, Huang X, Mi W, et al. Snail determines the therapeutic response to mTOR kinase inhibitors by transcriptional repression of 4E-BP1. Nat Commun. 2017;8:2207 pubmed 出版商
Lee H, Zhang D, Wu J, Otterbein L, Jin Y. Lung Epithelial Cell-Derived Microvesicles Regulate Macrophage Migration via MicroRNA-17/221-Induced Integrin ?1 Recycling. J Immunol. 2017;199:1453-1464 pubmed 出版商
Smith S, Mellor P, Ward A, Kendall S, McDonald M, Vizeacoumar F, et al. Molecular characterization of breast cancer cell lines through multiple omic approaches. Breast Cancer Res. 2017;19:65 pubmed 出版商
Yanagisawa S, Baker J, Vuppusetty C, Fenwick P, Donnelly L, Ito K, et al. Decreased phosphatase PTEN amplifies PI3K signaling and enhances proinflammatory cytokine release in COPD. Am J Physiol Lung Cell Mol Physiol. 2017;313:L230-L239 pubmed 出版商
Chen Z, Jiang H, Xu W, Li X, Dempsey D, Zhang X, et al. A Tunable Brake for HECT Ubiquitin Ligases. Mol Cell. 2017;66:345-357.e6 pubmed 出版商
Kim E, Kim G, Kim B, Lim E, Kim S, Kim Y. Apoptosis-induced effects of extract from Artemisia annua Linné by modulating PTEN/p53/PDK1/Akt/ signal pathways through PTEN/p53-independent manner in HCT116 colon cancer cells. BMC Complement Altern Med. 2017;17:236 pubmed 出版商
Belanger F, Rajotte V, Drobetsky E. A majority of human melanoma cell lines exhibits an S phase-specific defect in excision of UV-induced DNA photoproducts. PLoS ONE. 2014;9:e85294 pubmed 出版商
Sacco J, Yau T, Darling S, Patel V, Liu H, Urbé S, et al. The deubiquitylase Ataxin-3 restricts PTEN transcription in lung cancer cells. Oncogene. 2014;33:4265-72 pubmed 出版商
Patsoukis N, Li L, Sari D, Petkova V, Boussiotis V. PD-1 increases PTEN phosphatase activity while decreasing PTEN protein stability by inhibiting casein kinase 2. Mol Cell Biol. 2013;33:3091-8 pubmed 出版商
Arroba A, Revuelta Cervantes J, Menes L, Gonzalez Rodriguez A, Pardo V, de la Villa P, et al. Loss of protein tyrosine phosphatase 1B increases IGF-I receptor tyrosine phosphorylation but does not rescue retinal defects in IRS2-deficient mice. Invest Ophthalmol Vis Sci. 2013;54:4215-25 pubmed 出版商
Zhang S, Taghibiglou C, Girling K, Dong Z, Lin S, Lee W, et al. Critical role of increased PTEN nuclear translocation in excitotoxic and ischemic neuronal injuries. J Neurosci. 2013;33:7997-8008 pubmed 出版商
Chen J, Li Z, Chen A, Ye X, Luo H, Rankin G, et al. Inhibitory effect of baicalin and baicalein on ovarian cancer cells. Int J Mol Sci. 2013;14:6012-25 pubmed 出版商
Mussnich P, D Angelo D, Leone V, Croce C, Fusco A. The High Mobility Group A proteins contribute to thyroid cell transformation by regulating miR-603 and miR-10b expression. Mol Oncol. 2013;7:531-42 pubmed 出版商
Alam R, Schultz C, Golembieski W, Poisson L, Rempel S. PTEN suppresses SPARC-induced pMAPKAPK2 and inhibits SPARC-induced Ser78 HSP27 phosphorylation in glioma. Neuro Oncol. 2013;15:451-61 pubmed 出版商
Cai N, Wang Y, Zheng P. The microRNA-302-367 cluster suppresses the proliferation of cervical carcinoma cells through the novel target AKT1. RNA. 2013;19:85-95 pubmed 出版商
Litlekalsoy J, Hostmark J, Costea D, Illemann M, Laerum O. Time-dependent biological differences in molecular markers of high-grade urothelial cancer over 7 decades (ras proteins, pTEN, uPAR, PAI-1 and MMP-9). Virchows Arch. 2012;461:541-51 pubmed 出版商
Sharma I, Singh D. Conjugated linoleic acids attenuate FSH- and IGF1-stimulated cell proliferation; IGF1, GATA4, and aromatase expression; and estradiol-17? production in buffalo granulosa cells involving PPAR?, PTEN, and PI3K/Akt. Reproduction. 2012;144:373-83 pubmed 出版商
McIver S, Stanger S, Santarelli D, Roman S, Nixon B, McLaughlin E. A unique combination of male germ cell miRNAs coordinates gonocyte differentiation. PLoS ONE. 2012;7:e35553 pubmed 出版商
Krausch M, Raffel A, Anlauf M, Schott M, Willenberg H, Lehwald N, et al. Loss of PTEN expression in neuroendocrine pancreatic tumors. Horm Metab Res. 2011;43:865-71 pubmed 出版商
Singh G, Odriozola L, Guan H, Kennedy C, Chan A. Characterization of a novel PTEN mutation in MDA-MB-453 breast carcinoma cell line. BMC Cancer. 2011;11:490 pubmed 出版商
Yang S, Xiao X, Meng X, Leslie K. A mechanism for synergy with combined mTOR and PI3 kinase inhibitors. PLoS ONE. 2011;6:e26343 pubmed 出版商
Molina J, Agarwal N, Morales F, Hayashi Y, Aldape K, Cote G, et al. PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma. Oncogene. 2012;31:1264-74 pubmed 出版商
Deneubourg L, Ralea S, Gromova P, Parsons R, Vanderwinden J, Erneux C. Abnormal elevated PTEN expression in the mouse antrum of a model of GIST Kit(K641E/K641E). Cell Signal. 2011;23:1857-68 pubmed 出版商
Weidinger C, Krause K, Mueller K, Klagge A, Fuhrer D. FOXO3 is inhibited by oncogenic PI3K/Akt signaling but can be reactivated by the NSAID sulindac sulfide. J Clin Endocrinol Metab. 2011;96:E1361-71 pubmed 出版商
Pernicová Z, Slabáková E, Kharaishvili G, Bouchal J, Kral M, Kunická Z, et al. Androgen depletion induces senescence in prostate cancer cells through down-regulation of Skp2. Neoplasia. 2011;13:526-36 pubmed
Ben Sasson H, Ben Meir A, Shushan A, Karra L, Rojansky N, Klein B, et al. All-trans-retinoic acid mediates changes in PI3K and retinoic acid signaling proteins of leiomyomas. Fertil Steril. 2011;95:2080-6 pubmed 出版商
Xie R, Nguyen S, McKeehan K, Wang F, McKeehan W, Liu L. Microtubule-associated protein 1S (MAP1S) bridges autophagic components with microtubules and mitochondria to affect autophagosomal biogenesis and degradation. J Biol Chem. 2011;286:10367-77 pubmed 出版商
Nagao K, Yamamoto Y, Hara T, Komatsu H, Inoue R, Matsuda K, et al. Ki67 and BUBR1 may discriminate clinically insignificant prostate cancer in the PSA range <4 ng/ml. Jpn J Clin Oncol. 2011;41:555-64 pubmed 出版商
Proietti S, Cucina A, D Anselmi F, Dinicola S, Pasqualato A, Lisi E, et al. Melatonin and vitamin D3 synergistically down-regulate Akt and MDM2 leading to TGF?-1-dependent growth inhibition of breast cancer cells. J Pineal Res. 2011;50:150-8 pubmed 出版商
Axanova L, Chen Y, McCoy T, Sui G, Cramer S. 1,25-dihydroxyvitamin D(3) and PI3K/AKT inhibitors synergistically inhibit growth and induce senescence in prostate cancer cells. Prostate. 2010;70:1658-71 pubmed 出版商
Han S, Yun H, Son D, Tompkins V, Peng L, Chung S, et al. NF-kappaB/STAT3/PI3K signaling crosstalk in iMyc E mu B lymphoma. Mol Cancer. 2010;9:97 pubmed 出版商
Udo K, Aoki S, Uchihashi K, Kawasaki M, Matsunobu A, Tokuda Y, et al. Adipose tissue explants and MDCK cells reciprocally regulate their morphogenesis in coculture. Kidney Int. 2010;78:60-8 pubmed 出版商
Ruschmann J, Ho V, Antignano F, Kuroda E, Lam V, Ibaraki M, et al. Tyrosine phosphorylation of SHIP promotes its proteasomal degradation. Exp Hematol. 2010;38:392-402, 402.e1 pubmed 出版商
Cho H, Gladwell W, Wang X, Chorley B, Bell D, Reddy S, et al. Nrf2-regulated PPAR{gamma} expression is critical to protection against acute lung injury in mice. Am J Respir Crit Care Med. 2010;182:170-82 pubmed 出版商
Capaccio D, Ciccodicola A, Sabatino L, Casamassimi A, Pancione M, Fucci A, et al. A novel germline mutation in peroxisome proliferator-activated receptor gamma gene associated with large intestine polyp formation and dyslipidemia. Biochim Biophys Acta. 2010;1802:572-81 pubmed 出版商
Zhang L, Deng T, Li X, Liu H, Zhou H, Ma J, et al. microRNA-141 is involved in a nasopharyngeal carcinoma-related genes network. Carcinogenesis. 2010;31:559-66 pubmed 出版商
Peng C, Chen Y, Yang Z, Zhang H, Osterby L, Rosmarin A, et al. PTEN is a tumor suppressor in CML stem cells and BCR-ABL-induced leukemias in mice. Blood. 2010;115:626-35 pubmed 出版商
Omerovic J, Clague M, Prior I. Phosphatome profiling reveals PTPN2, PTPRJ and PTEN as potent negative regulators of PKB/Akt activation in Ras-mutated cancer cells. Biochem J. 2010;426:65-72 pubmed 出版商
Kuijk E, van Mil A, Brinkhof B, Penning L, Colenbrander B, Roelen B. PTEN and TRP53 independently suppress Nanog expression in spermatogonial stem cells. Stem Cells Dev. 2010;19:979-88 pubmed 出版商
Cosse J, Ronvaux M, Ninane N, Raes M, Michiels C. Hypoxia-induced decrease in p53 protein level and increase in c-jun DNA binding activity results in cancer cell resistance to etoposide. Neoplasia. 2009;11:976-86 pubmed
Karra L, Shushan A, Ben Meir A, Rojansky N, Klein B, Shveiky D, et al. Changes related to phosphatidylinositol 3-kinase/Akt signaling in leiomyomas: possible involvement of glycogen synthase kinase 3alpha and cyclin D2 in the pathophysiology. Fertil Steril. 2010;93:2646-51 pubmed 出版商
Lincová E, Hampl A, Pernicová Z, Starsíchová A, Krcmar P, Machala M, et al. Multiple defects in negative regulation of the PKB/Akt pathway sensitise human cancer cells to the antiproliferative effect of non-steroidal anti-inflammatory drugs. Biochem Pharmacol. 2009;78:561-72 pubmed 出版商
Caldera V, Mellai M, Annovazzi L, Valente G, Tessitore L, Schiffer D. Stat3 expression and its correlation with proliferation and apoptosis/autophagy in gliomas. J Oncol. 2008;2008:219241 pubmed 出版商
Lorente A, Mueller W, Urdangarín E, Lázcoz P, Lass U, von Deimling A, et al. RASSF1A, BLU, NORE1A, PTEN and MGMT expression and promoter methylation in gliomas and glioma cell lines and evidence of deregulated expression of de novo DNMTs. Brain Pathol. 2009;19:279-92 pubmed 出版商
Wang C, Lin Y, Yang J. Activation of protein kinase Calpha signaling prevents cytotoxicity and mutagenicity following lead acetate in CL3 human lung cancer cells. Toxicology. 2008;250:55-61 pubmed 出版商
Frew I, Minola A, Georgiev S, Hitz M, Moch H, Richard S, et al. Combined VHLH and PTEN mutation causes genital tract cystadenoma and squamous metaplasia. Mol Cell Biol. 2008;28:4536-48 pubmed 出版商
Geoerger B, Gaspar N, Opolon P, Morizet J, Devanz P, Lecluse Y, et al. EGFR tyrosine kinase inhibition radiosensitizes and induces apoptosis in malignant glioma and childhood ependymoma xenografts. Int J Cancer. 2008;123:209-16 pubmed 出版商
Lee Y, Kang S, Kim B, Kim Y, Woo H, Chung H. Cytotoxicity of honeybee (Apis mellifera) venom in normal human lymphocytes and HL-60 cells. Chem Biol Interact. 2007;169:189-97 pubmed
Marangoni E, Vincent Salomon A, Auger N, Degeorges A, Assayag F, De Cremoux P, et al. A new model of patient tumor-derived breast cancer xenografts for preclinical assays. Clin Cancer Res. 2007;13:3989-98 pubmed
Strumane K, Song J, Baas I, Collard J. Increased Rac activity is required for the progression of T-lymphomas induced by Pten-deficiency. Leuk Res. 2008;32:113-20 pubmed
Kim K, Shin H, Kim K, Choi H, Rhee S, Moon H, et al. Hepatitis B virus X protein induces hepatic steatosis via transcriptional activation of SREBP1 and PPARgamma. Gastroenterology. 2007;132:1955-67 pubmed
Feng Z, Hu W, de Stanchina E, Teresky A, Jin S, Lowe S, et al. The regulation of AMPK beta1, TSC2, and PTEN expression by p53: stress, cell and tissue specificity, and the role of these gene products in modulating the IGF-1-AKT-mTOR pathways. Cancer Res. 2007;67:3043-53 pubmed
Zheng Z, Chen T, Li X, Haura E, Sharma A, Bepler G. DNA synthesis and repair genes RRM1 and ERCC1 in lung cancer. N Engl J Med. 2007;356:800-8 pubmed
Xia W, Husain I, Liu L, Bacus S, Saini S, Spohn J, et al. Lapatinib antitumor activity is not dependent upon phosphatase and tensin homologue deleted on chromosome 10 in ErbB2-overexpressing breast cancers. Cancer Res. 2007;67:1170-5 pubmed
Nieto Vazquez I, Fernández Veledo S, de Alvaro C, Rondinone C, Valverde A, Lorenzo M. Protein-tyrosine phosphatase 1B-deficient myocytes show increased insulin sensitivity and protection against tumor necrosis factor-alpha-induced insulin resistance. Diabetes. 2007;56:404-13 pubmed
Fernandez Veledo S, Nieto Vazquez I, Rondinone C, Lorenzo M. Liver X receptor agonists ameliorate TNFalpha-induced insulin resistance in murine brown adipocytes by downregulating protein tyrosine phosphatase-1B gene expression. Diabetologia. 2006;49:3038-48 pubmed
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产品信息
产品名称 :
磷酸酶张力蛋白同源基因(A2B1)抗体
基因名称 :
磷酸酶张力蛋白同源基因
规格 :
200微克/毫升
目录号 :
sc-7974
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
磷酸酶张力蛋白同源基因
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), 酶联免疫吸附测定
表位 :
388-400(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
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