产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
雌激素受体α(D-12)抗体
目录 :
sc-8005
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
D-12
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 51
出版应用/物种/样品/稀释参考文献
  • 免疫细胞化学; 人类; 1:50
  • 免疫印迹; 人类; 图 2a
Bostner J, Alayev A, Berman A, Fornander T, Nordenskjold B, Holz M, et al. Raptor localization predicts prognosis and tamoxifen response in estrogen receptor-positive breast cancer. Breast Cancer Res Treat. 2018;168:17-27 pubmed 出版商
  • 免疫印迹; 人类; 图 1c
Thaler S, Schmidt M, Roβwag S, Thiede G, Schad A, Sleeman J. Proteasome inhibitors prevent bi-directional HER2/estrogen-receptor cross-talk leading to cell death in endocrine and lapatinib-resistant HER2+/ER+ breast cancer cells. Oncotarget. 2017;8:72281-72301 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:50; 图 4a
Wu D, Kimura F, Zheng L, Ishida M, Niwa Y, Hirata K, et al. Chronic endometritis modifies decidualization in human endometrial stromal cells. Reprod Biol Endocrinol. 2017;15:16 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 6
Piggin C, Roden D, Gallego Ortega D, Lee H, Oakes S, Ormandy C. ELF5 isoform expression is tissue-specific and significantly altered in cancer. Breast Cancer Res. 2016;18:4 pubmed 出版商
  • 免疫细胞化学; 人类; 图 1
  • 免疫印迹; 人类; 图 5
Alayev A, Salamon R, Berger S, Schwartz N, Cuesta R, Snyder R, et al. mTORC1 directly phosphorylates and activates ERα upon estrogen stimulation. Oncogene. 2016;35:3535-43 pubmed 出版商
  • 免疫印迹; 小鼠; 1:300
Bacallao K, Plaza Parrochia F, Cerda A, Gabler F, Romero C, Vantman D, et al. Levels of Regulatory Proteins Associated With Cell Proliferation in Endometria From Untreated Patients Having Polycystic Ovarian Syndrome With and Without Endometrial Hyperplasia. Reprod Sci. 2016;23:211-8 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Montt Guevara M, Giretti M, Russo E, Giannini A, Mannella P, Genazzani A, et al. Estetrol Modulates Endothelial Nitric Oxide Synthesis in Human Endothelial Cells. Front Endocrinol (Lausanne). 2015;6:111 pubmed 出版商
  • 免疫印迹; 人类; 图 2b, s1c
Wardell S, Nelson E, Chao C, Alley H, McDonnell D. Evaluation of the pharmacological activities of RAD1901, a selective estrogen receptor degrader. Endocr Relat Cancer. 2015;22:713-24 pubmed 出版商
  • 免疫印迹; 人类
Teng Y, Radde B, Litchfield L, Ivanova M, Prough R, Clark B, et al. Dehydroepiandrosterone Activation of G-protein-coupled Estrogen Receptor Rapidly Stimulates MicroRNA-21 Transcription in Human Hepatocellular Carcinoma Cells. J Biol Chem. 2015;290:15799-811 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 1f
Li Y, Wu Y, Abbatiello T, Wu W, Kim J, Sarkissyan M, et al. Slug contributes to cancer progression by direct regulation of ERα signaling pathway. Int J Oncol. 2015;46:1461-72 pubmed 出版商
  • 免疫印迹; 人类
Papanikolaou V, Stefanou N, Dubos S, Papathanasiou I, Palianopoulou M, Valiakou V, et al. Synergy of leptin/STAT3 with HER2 receptor induces tamoxifen resistance in breast cancer cells through regulation of apoptosis-related genes. Cell Oncol (Dordr). 2015;38:155-64 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:75
Bouchekioua Bouzaghou K, Poulard C, Rambaud J, Lavergne E, Hussein N, Billaud M, et al. LKB1 when associated with methylatedER? is a marker of bad prognosis in breast cancer. Int J Cancer. 2014;135:1307-18 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Dhasarathy A, Kajita M, Wade P. The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha. Mol Endocrinol. 2007;21:2907-18 pubmed
Swetzig W, Wang J, Das G. Estrogen receptor alpha (ERα/ESR1) mediates the p53-independent overexpression of MDM4/MDMX and MDM2 in human breast cancer. Oncotarget. 2016;7:16049-69 pubmed 出版商
Poulard C, Rambaud J, Hussein N, Corbo L, Le Romancer M. JMJD6 regulates ER? methylation on arginine. PLoS ONE. 2014;9:e87982 pubmed 出版商
Kobelt L, Klammt J, Tefs K, Schuster V. Estrogen modulates plasminogen promoter activity. Biochem Biophys Res Commun. 2013;438:110-5 pubmed 出版商
Huang P, Huang C, Chen M, Lee Y, Yue C, Wang H, et al. Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ER ? Inhibition. Evid Based Complement Alternat Med. 2013;2013:376123 pubmed 出版商
Kharbanda A, Rajabi H, Jin C, Raina D, Kufe D. Oncogenic MUC1-C promotes tamoxifen resistance in human breast cancer. Mol Cancer Res. 2013;11:714-23 pubmed 出版商
Wardell S, Nelson E, Chao C, McDonnell D. Bazedoxifene exhibits antiestrogenic activity in animal models of tamoxifen-resistant breast cancer: implications for treatment of advanced disease. Clin Cancer Res. 2013;19:2420-31 pubmed 出版商
Inaba T, Kobayashi T, Tsutsui T, Ogawa M, Uchida M, Tsutsui T. Expression status of mRNA for sex hormone receptors in human dental pulp cells and the response to sex hormones in the cells. Arch Oral Biol. 2013;58:943-50 pubmed 出版商
Simmons M, Serra R, Hermance N, Kelliher M. NOTCH1 inhibition in vivo results in mammary tumor regression and reduced mammary tumorsphere-forming activity in vitro. Breast Cancer Res. 2012;14:R126 pubmed 出版商
Marconett C, Singhal A, Sundar S, Firestone G. Indole-3-carbinol disrupts estrogen receptor-alpha dependent expression of insulin-like growth factor-1 receptor and insulin receptor substrate-1 and proliferation of human breast cancer cells. Mol Cell Endocrinol. 2012;363:74-84 pubmed 出版商
Guido C, Panza S, Santoro M, Avena P, Panno M, Perrotta I, et al. Estrogen receptor beta (ER?) produces autophagy and necroptosis in human seminoma cell line through the binding of the Sp1 on the phosphatase and tensin homolog deleted from chromosome 10 (PTEN) promoter gene. Cell Cycle. 2012;11:2911-21 pubmed 出版商
Liu W, Swetzig W, Medisetty R, Das G. Estrogen-mediated upregulation of Noxa is associated with cell cycle progression in estrogen receptor-positive breast cancer cells. PLoS ONE. 2011;6:e29466 pubmed 出版商
Piastowska Ciesielska A, Płuciennik E, Wójcik Krowiranda K, Bienkiewicz A, Bednarek A, Ochedalski T. Analysis of the expression of angiotensin II type 1 receptor and VEGF in endometrial adenocarcinoma with different clinicopathological characteristics. Tumour Biol. 2012;33:767-74 pubmed 出版商
Papanikolaou V, Athanassiou E, Dubos S, Dimou I, Papathanasiou I, Kitsiou Tzeli S, et al. hTERT regulation by NF-?B and c-myc in irradiated HER2-positive breast cancer cells. Int J Radiat Biol. 2011;87:609-21 pubmed 出版商
Wardell S, Marks J, McDonnell D. The turnover of estrogen receptor ? by the selective estrogen receptor degrader (SERD) fulvestrant is a saturable process that is not required for antagonist efficacy. Biochem Pharmacol. 2011;82:122-30 pubmed 出版商
Alimirah F, Peng X, Murillo G, Mehta R. Functional significance of vitamin D receptor FokI polymorphism in human breast cancer cells. PLoS ONE. 2011;6:e16024 pubmed 出版商
Sharma G, Mirza S, Parshad R, Srivastava A, Gupta S, Pandya P, et al. Clinical significance of promoter hypermethylation of DNA repair genes in tumor and serum DNA in invasive ductal breast carcinoma patients. Life Sci. 2010;87:83-91 pubmed 出版商
Lee S, Lee S, Ha N, Park B. Estrogen prevents senescence through induction of WRN, Werner syndrome protein. Horm Res Paediatr. 2010;74:33-40 pubmed 出版商
Peidis P, Giannakouros T, Burow M, Williams R, Scott R. Systems genetics analyses predict a transcription role for P2P-R: molecular confirmation that P2P-R is a transcriptional co-repressor. BMC Syst Biol. 2010;4:14 pubmed 出版商
Marconett C, Sundar S, Poindexter K, Stueve T, Bjeldanes L, Firestone G. Indole-3-carbinol triggers aryl hydrocarbon receptor-dependent estrogen receptor (ER)alpha protein degradation in breast cancer cells disrupting an ERalpha-GATA3 transcriptional cross-regulatory loop. Mol Biol Cell. 2010;21:1166-77 pubmed 出版商
Mirza S, Sharma G, Parshad R, Srivastava A, Gupta S, Ralhan R. Clinical significance of Stratifin, ERalpha and PR promoter methylation in tumor and serum DNA in Indian breast cancer patients. Clin Biochem. 2010;43:380-6 pubmed 出版商
Prasad C, Rath G, Mathur S, Bhatnagar D, Ralhan R. Expression analysis of maspin in invasive ductal carcinoma of breast and modulation of its expression by curcumin in breast cancer cell lines. Chem Biol Interact. 2010;183:455-61 pubmed 出版商
Sharma G, Mirza S, Yang Y, Parshad R, Hazrah P, Datta Gupta S, et al. Prognostic relevance of promoter hypermethylation of multiple genes in breast cancer patients. Cell Oncol. 2009;31:487-500 pubmed 出版商
Taslim C, Wu J, Yan P, Singer G, Parvin J, Huang T, et al. Comparative study on ChIP-seq data: normalization and binding pattern characterization. Bioinformatics. 2009;25:2334-40 pubmed 出版商
Wong J, Weickert C. Transcriptional interaction of an estrogen receptor splice variant and ErbB4 suggests convergence in gene susceptibility pathways in schizophrenia. J Biol Chem. 2009;284:18824-32 pubmed 出版商
Polotsky A, Zhu L, Santoro N, Pollard J. Lithium chloride treatment induces epithelial cell proliferation in xenografted human endometrium. Hum Reprod. 2009;24:1960-7 pubmed 出版商
Schultz Norton J, Ziegler Y, Likhite V, Yates J, Nardulli A. Isolation of novel coregulatory protein networks associated with DNA-bound estrogen receptor alpha. BMC Mol Biol. 2008;9:97 pubmed 出版商
Feng W, Liu Y, Wu J, Nephew K, Huang T, Li L. A Poisson mixture model to identify changes in RNA polymerase II binding quantity using high-throughput sequencing technology. BMC Genomics. 2008;9 Suppl 2:S23 pubmed 出版商
Thasni K, Rakesh S, Rojini G, Ratheeshkumar T, Srinivas G, Priya S. Estrogen-dependent cell signaling and apoptosis in BRCA1-blocked BG1 ovarian cancer cells in response to plumbagin and other chemotherapeutic agents. Ann Oncol. 2008;19:696-705 pubmed 出版商
Curtis C, Likhite V, McLeod I, Yates J, Nardulli A. Interaction of the tumor metastasis suppressor nonmetastatic protein 23 homologue H1 and estrogen receptor alpha alters estrogen-responsive gene expression. Cancer Res. 2007;67:10600-7 pubmed
Mirza S, Sharma G, Prasad C, Parshad R, Srivastava A, Gupta S, et al. Promoter hypermethylation of TMS1, BRCA1, ERalpha and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients. Life Sci. 2007;81:280-7 pubmed
Schultz Norton J, Walt K, Ziegler Y, McLeod I, Yates J, Raetzman L, et al. The deoxyribonucleic acid repair protein flap endonuclease-1 modulates estrogen-responsive gene expression. Mol Endocrinol. 2007;21:1569-80 pubmed
Niklaus A, Aubuchon M, Zapantis G, Li P, Qian H, Isaac B, et al. Assessment of the proliferative status of epithelial cell types in the endometrium of young and menopausal transition women. Hum Reprod. 2007;22:1778-88 pubmed
Schmidt A, Nanney L, Boyd A, King L, Ellis D. Oestrogen receptor-beta expression in melanocytic lesions. Exp Dermatol. 2006;15:971-80 pubmed
Scoles D, Pavelka J, Cass I, Tran H, Baldwin R, Armstrong K, et al. Characterization of CSOC 882, a novel immortalized ovarian cancer cell line expressing EGFR, HER2, and activated AKT. Gynecol Oncol. 2007;104:120-8 pubmed
Al Dhaheri M, Rowan B. Application of phosphorylation site-specific antibodies to measure nuclear receptor signaling: characterization of novel phosphoantibodies for estrogen receptor alpha. Nucl Recept Signal. 2006;4:e007 pubmed
Koduri S, Goldhar A, Vonderhaar B. Activation of vascular endothelial growth factor (VEGF) by the ER-alpha variant, ERDelta3. Breast Cancer Res Treat. 2006;95:37-43 pubmed
Fog C, Christensen I, Lykkesfeldt A. Characterization of a human breast cancer cell line, MCF-7/RU58R-1, resistant to the pure antiestrogen RU 58,668. Breast Cancer Res Treat. 2005;91:133-44 pubmed
Ji Q, Liu P, Elshimali Y, Stolz A. Frequent loss of estrogen and progesterone receptors in human prostatic tumors determined by quantitative real-time PCR. Mol Cell Endocrinol. 2005;229:103-10 pubmed
产品信息
产品名称 :
雌激素受体α(D-12)抗体
基因名称 :
ESR1
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-8005
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
雌激素受体α
反应物种 :
人类
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), 酶联免疫吸附测定
表位 :
N末端(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。