产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
Stat3(F-2)抗体
目录 :
sc-8019
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
F-2
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 73
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 1:2000; 图 s2c
Rizzini L, Levine D, Perelis M, Bass J, Peek C, Pagano M. Cryptochromes-Mediated Inhibition of the CRL4Cop1-Complex Assembly Defines an Evolutionary Conserved Signaling Mechanism. Curr Biol. 2019;29:1954-1962.e4 pubmed 出版商
  • 免疫印迹; 大鼠; 1:200; 图 5
Li J, Liu B, Shi Y, Xie K, Yin H, Yan L, et al. CXCL4 Contributes to the Pathogenesis of Chronic Liver Allograft Dysfunction. J Immunol Res. 2016;2016:9276986 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Tsuboki J, Fujiwara Y, Horlad H, Shiraishi D, Nohara T, Tayama S, et al. Onionin A inhibits ovarian cancer progression by suppressing cancer cell proliferation and the protumour function of macrophages. Sci Rep. 2016;6:29588 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Huang J, Yao C, Chuang S, Yeh C, Lee L, Chen R, et al. Honokiol inhibits sphere formation and xenograft growth of oral cancer side population cells accompanied with JAK/STAT signaling pathway suppression and apoptosis induction. BMC Cancer. 2016;16:245 pubmed 出版商
  • 免疫印迹; 人类; 图 2d
Atiq R, Hertz R, Eldad S, Smeir E, Bar Tana J. Suppression of B-Raf(V600E) cancers by MAPK hyper-activation. Oncotarget. 2016;7:18694-704 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 4
  • 免疫印迹; 人类; 图 4
Renga B, Francisci D, Carino A, Marchianò S, Cipriani S, Chiara Monti M, et al. The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma. Sci Rep. 2015;5:15403 pubmed 出版商
  • 免疫印迹; 人类; 图 s13
Kawada M, Inoue H, Ohba S, Yoshida J, Masuda T, Yamasaki M, et al. Stromal cells positively and negatively modulate the growth of cancer cells: stimulation via the PGE2-TNFα-IL-6 pathway and inhibition via secreted GAPDH-E-cadherin interaction. PLoS ONE. 2015;10:e0119415 pubmed 出版商
  • 免疫印迹; 小鼠
Mou W, Xu Y, Ye Y, Chen S, Li X, Gong K, et al. Expression of Sox2 in breast cancer cells promotes the recruitment of M2 macrophages to tumor microenvironment. Cancer Lett. 2015;358:115-23 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Thagia I, Shaw E, Smith E, Else K, Rigby R. Intestinal epithelial suppressor of cytokine signaling 3 enhances microbial-induced inflammatory tumor necrosis factor-α, contributing to epithelial barrier dysfunction. Am J Physiol Gastrointest Liver Physiol. 2015;308:G25-31 pubmed 出版商
  • 免疫细胞化学; 人类
Cheray M, Nadaradjane A, Bonnet P, Routier S, Vallette F, Cartron P. Specific inhibition of DNMT1/CFP1 reduces cancer phenotypes and enhances chemotherapy effectiveness. Epigenomics. 2014;6:267-75 pubmed 出版商
  • 免疫印迹; 人类
George S, Vishwamitra D, Manshouri R, Shi P, Amin H. The ALK inhibitor ASP3026 eradicates NPM-ALK? T-cell anaplastic large-cell lymphoma in vitro and in a systemic xenograft lymphoma model. Oncotarget. 2014;5:5750-63 pubmed
Chesnelong C, Hao X, Cseh O, Wang A, Luchman H, Weiss S. SLUG Directs the Precursor State of Human Brain Tumor Stem Cells. Cancers (Basel). 2019;11: pubmed 出版商
Martínez García D, Pérez Hernández M, Korrodi Gregório L, Quesada R, Ramos R, Baixeras N, et al. The Natural-Based Antitumor Compound T21 Decreases Survivin Levels through Potent STAT3 Inhibition in Lung Cancer Models. Biomolecules. 2019;9: pubmed 出版商
Lee J, Chang J, Dominguez A, Lee H, Nam S, Chang J, et al. YAP-independent mechanotransduction drives breast cancer progression. Nat Commun. 2019;10:1848 pubmed 出版商
Shi Y, Gao W, Lytle N, Huang P, Yuan X, Dann A, et al. Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring. Nature. 2019;569:131-135 pubmed 出版商
Kim H, Kim D, Choi S, Kim C, Oh S, Pyo K, et al. KDM3A histone demethylase functions as an essential factor for activation of JAK2-STAT3 signaling pathway. Proc Natl Acad Sci U S A. 2018;115:11766-11771 pubmed 出版商
Xiong Y, Torsoni A, Wu F, Shen H, Liu Y, Zhong X, et al. Hepatic NF-kB-inducing kinase (NIK) suppresses mouse liver regeneration in acute and chronic liver diseases. elife. 2018;7: pubmed 出版商
He F, Soriano P. Dysregulated PDGFRα signaling alters coronal suture morphogenesis and leads to craniosynostosis through endochondral ossification. Development. 2017;144:4026-4036 pubmed 出版商
Read K, Powell M, Baker C, Sreekumar B, Ringel Scaia V, Bachus H, et al. Integrated STAT3 and Ikaros Zinc Finger Transcription Factor Activities Regulate Bcl-6 Expression in CD4+ Th Cells. J Immunol. 2017;199:2377-2387 pubmed 出版商
Yoon S, Kovalenko A, Bogdanov K, Wallach D. MLKL, the Protein that Mediates Necroptosis, Also Regulates Endosomal Trafficking and Extracellular Vesicle Generation. Immunity. 2017;47:51-65.e7 pubmed 出版商
Zhang Z, Luo Z, Min W, Zhang L, Wu Y, Hu X. An anti-cancer WxxxE-containing azurin polypeptide inhibits Rac1-dependent STAT3 and ERK/GSK-3? signaling in breast cancer cells. Oncotarget. 2017;8:43091-43103 pubmed 出版商
Yoon J, Sudo K, Kuroda M, Kato M, Lee I, Han J, et al. Phosphorylation status determines the opposing functions of Smad2/Smad3 as STAT3 cofactors in TH17 differentiation. Nat Commun. 2015;6:7600 pubmed 出版商
He B, Hao J, Sheng W, Xiang Y, Zhang J, Zhu H, et al. Fistular onion stalk extract exhibits anti-atherosclerotic effects in rats. Exp Ther Med. 2014;8:785-792 pubmed
Yang H, Lawrence H, Kazi A, Gevariya H, Patel R, Luo Y, et al. Dual Aurora A and JAK2 kinase blockade effectively suppresses malignant transformation. Oncotarget. 2014;5:2947-61 pubmed
Renga B, Francisci D, Schiaroli E, Carino A, Cipriani S, D Amore C, et al. The HIV matrix protein p17 promotes the activation of human hepatic stellate cells through interactions with CXCR2 and Syndecan-2. PLoS ONE. 2014;9:e94798 pubmed 出版商
Fujiwara Y, Takaishi K, Nakao J, Ikeda T, Katabuchi H, Takeya M, et al. Corosolic acid enhances the antitumor effects of chemotherapy on epithelial ovarian cancer by inhibiting signal transducer and activator of transcription 3 signaling. Oncol Lett. 2013;6:1619-1623 pubmed
Wang Z, Si X, Xu A, Meng X, Gao S, Qi Y, et al. Activation of STAT3 in human gastric cancer cells via interleukin (IL)-6-type cytokine signaling correlates with clinical implications. PLoS ONE. 2013;8:e75788 pubmed 出版商
Bogazzi F, Raggi F, Russo D, Bohlooly Y M, Sardella C, Urbani C, et al. Growth hormone is necessary for the p53-mediated, obesity-induced insulin resistance in male C57BL/6J x CBA mice. Endocrinology. 2013;154:4226-36 pubmed 出版商
Zhang P, Zhang P, Zhou M, Jiang H, Zhang H, Shi B, et al. Exon 4 deletion variant of epidermal growth factor receptor enhances invasiveness and cisplatin resistance in epithelial ovarian cancer. Carcinogenesis. 2013;34:2639-46 pubmed 出版商
Ding B, Bi E, Chen H, Yu J, Ye B. IL-21 and CD40L synergistically promote plasma cell differentiation through upregulation of Blimp-1 in human B cells. J Immunol. 2013;190:1827-36 pubmed 出版商
Bu X, Zhao C, Wang W, Zhang N. GRIM-19 inhibits the STAT3 signaling pathway and sensitizes gastric cancer cells to radiation. Gene. 2013;512:198-205 pubmed 出版商
Wang J, Chen S, Xu S, Yu X, Ma D, Hu X, et al. In vivo induction of apoptosis by fucoxanthin, a marine carotenoid, associated with down-regulating STAT3/EGFR signaling in sarcoma 180 (S180) xenografts-bearing mice. Mar Drugs. 2012;10:2055-68 pubmed 出版商
Duru N, Fan M, Candas D, Menaa C, Liu H, Nantajit D, et al. HER2-associated radioresistance of breast cancer stem cells isolated from HER2-negative breast cancer cells. Clin Cancer Res. 2012;18:6634-47 pubmed 出版商
Zgheib C, Kurdi M, Zouein F, Gunter B, Stanley B, Zgheib J, et al. Acyloxy nitroso compounds inhibit LIF signaling in endothelial cells and cardiac myocytes: evidence that STAT3 signaling is redox-sensitive. PLoS ONE. 2012;7:e43313 pubmed 出版商
Shiraishi D, Fujiwara Y, Komohara Y, Mizuta H, Takeya M. Glucagon-like peptide-1 (GLP-1) induces M2 polarization of human macrophages via STAT3 activation. Biochem Biophys Res Commun. 2012;425:304-8 pubmed 出版商
Gong J, Zhang J, Li B, Zeng C, You K, Chen M, et al. MicroRNA-125b promotes apoptosis by regulating the expression of Mcl-1, Bcl-w and IL-6R. Oncogene. 2013;32:3071-9 pubmed 出版商
Vishwamitra D, Li Y, Wilson D, Manshouri R, Curry C, Shi B, et al. MicroRNA 96 is a post-transcriptional suppressor of anaplastic lymphoma kinase expression. Am J Pathol. 2012;180:1772-80 pubmed 出版商
Teng S, Hsu W, Chiu C, Wong M, Chang S. Overexpression of P-glycoprotein, STAT3, phospho-STAT3 and KIT in spontaneous canine cutaneous mast cell tumours before and after prednisolone treatment. Vet J. 2012;193:551-6 pubmed 出版商
Nicolas C, Peineau S, Amici M, Csaba Z, Fafouri A, Javalet C, et al. The Jak/STAT pathway is involved in synaptic plasticity. Neuron. 2012;73:374-90 pubmed 出版商
Uluer E, Aydemir I, Inan S, Ozbilgin K, Vatansever H. Effects of 5-fluorouracil and gemcitabine on a breast cancer cell line (MCF-7) via the JAK/STAT pathway. Acta Histochem. 2012;114:641-6 pubmed 出版商
Kienesberger P, Pulinilkunnil T, Sung M, Nagendran J, Haemmerle G, Kershaw E, et al. Myocardial ATGL overexpression decreases the reliance on fatty acid oxidation and protects against pressure overload-induced cardiac dysfunction. Mol Cell Biol. 2012;32:740-50 pubmed 出版商
Osinalde N, Moss H, Arrizabalaga O, Omaetxebarria M, Blagoev B, Zubiaga A, et al. Interleukin-2 signaling pathway analysis by quantitative phosphoproteomics. J Proteomics. 2011;75:177-91 pubmed 出版商
Yin Z, Zhang Y, Li Y, Lv T, Liu J, Wang X. Prognostic significance of STAT3 expression and its correlation with chemoresistance of non-small cell lung cancer cells. Acta Histochem. 2012;114:151-8 pubmed 出版商
O Neil B, Goff L, Kauh J, Strosberg J, Bekaii Saab T, Lee R, et al. Phase II study of the mitogen-activated protein kinase 1/2 inhibitor selumetinib in patients with advanced hepatocellular carcinoma. J Clin Oncol. 2011;29:2350-6 pubmed 出版商
Thomas C, Zoubeidi A, Kuruma H, Fazli L, Lamoureux F, Beraldi E, et al. Transcription factor Stat5 knockdown enhances androgen receptor degradation and delays castration-resistant prostate cancer progression in vivo. Mol Cancer Ther. 2011;10:347-59 pubmed 出版商
Yu R, Hu X, Xu S, Jiang Z, Yang W. Effects of fucoxanthin on proliferation and apoptosis in human gastric adenocarcinoma MGC-803 cells via JAK/STAT signal pathway. Eur J Pharmacol. 2011;657:10-9 pubmed 出版商
Macha M, Matta A, Chauhan S, Siu K, Ralhan R. Guggulsterone (GS) inhibits smokeless tobacco and nicotine-induced NF-?B and STAT3 pathways in head and neck cancer cells. Carcinogenesis. 2011;32:368-80 pubmed 出版商
Glienke W, Hausmann E, Bergmann L. Downregulation of STAT3 signaling induces apoptosis but also promotes anti-apoptotic gene expression in human pancreatic cancer cell lines. Tumour Biol. 2011;32:493-500 pubmed 出版商
Fujiwara Y, Komohara Y, Ikeda T, Takeya M. Corosolic acid inhibits glioblastoma cell proliferation by suppressing the activation of signal transducer and activator of transcription-3 and nuclear factor-kappa B in tumor cells and tumor-associated macrophages. Cancer Sci. 2011;102:206-11 pubmed 出版商
Shen Y, Inoue N, Heese K. Neurotrophin-4 (ntf4) mediates neurogenesis in mouse embryonic neural stem cells through the inhibition of the signal transducer and activator of transcription-3 (stat3) and the modulation of the activity of protein kinase B. Cell Mol Neurobiol. 2010;30:909-16 pubmed 出版商
Madrigal Matute J, Lopez Franco O, Blanco Colio L, Munoz Garcia B, Ramos Mozo P, Ortega L, et al. Heat shock protein 90 inhibitors attenuate inflammatory responses in atherosclerosis. Cardiovasc Res. 2010;86:330-7 pubmed 出版商
Siejka A, Schally A, Barabutis N. Activation of Janus kinase/signal transducer and activator of transcription 3 pathway by growth hormone-releasing hormone. Cell Mol Life Sci. 2010;67:959-64 pubmed 出版商
Yao C, Yang C, Chuang S, Yan J, Liu C, Chen S, et al. Targeting PML-RAR? and Oncogenic Signaling Pathways by Chinese Herbal Mixture Tien-Hsien Liquid in Acute Promyelocytic Leukemia NB4 Cells. Evid Based Complement Alternat Med. 2011;2011:984154 pubmed 出版商
Chusid L, Pereira Argenziano L, Miskolci V, Vancurova I, Davidson D. Transcriptional control of cytokine release from monocytes of the newborn: effects of endogenous and exogenous interleukin-10 versus dexamethasone. Neonatology. 2010;97:108-16 pubmed 出版商
Wang L, Quan J, Johnston W, Maass D, Horton J, Thomas J, et al. Age-dependent differences of interleukin-6 activity in cardiac function after burn complicated by sepsis. Burns. 2010;36:232-8 pubmed 出版商
Yao X, Kodeboyina S, Liu L, Dzandu J, Sangerman J, Ofori Acquah S, et al. Role of STAT3 and GATA-1 interactions in gamma-globin gene expression. Exp Hematol. 2009;37:889-900 pubmed 出版商
Zorde Khvalevsky E, Abramovitch R, Barash H, Spivak Pohis I, Rivkin L, Rachmilewitz J, et al. Toll-like receptor 3 signaling attenuates liver regeneration. Hepatology. 2009;50:198-206 pubmed 出版商
Shah N, Trivedi T, Tankshali R, Goswami J, Jetly D, Shukla S, et al. Prognostic significance of molecular markers in oral squamous cell carcinoma: a multivariate analysis. Head Neck. 2009;31:1544-56 pubmed 出版商
Baral R, Bose A, Ray C, Paul S, Pal S, Haque E, et al. Association of early phase of colorectal carcinogenesis with STAT3 activation and its relevance in apoptosis regulation. Exp Mol Pathol. 2009;87:36-41 pubmed 出版商
Zhu P, Hata R, Cao F, Gu F, Hanakawa Y, Hashimoto K, et al. Ramified microglial cells promote astrogliogenesis and maintenance of neural stem cells through activation of Stat3 function. FASEB J. 2008;22:3866-77 pubmed 出版商
Itabashi H, Maesawa C, Oikawa H, Kotani K, Sakurai E, Kato K, et al. Angiotensin II and epidermal growth factor receptor cross-talk mediated by a disintegrin and metalloprotease accelerates tumor cell proliferation of hepatocellular carcinoma cell lines. Hepatol Res. 2008;38:601-13 pubmed 出版商
Nechemia Arbely Y, Barkan D, Pizov G, Shriki A, Rose John S, Galun E, et al. IL-6/IL-6R axis plays a critical role in acute kidney injury. J Am Soc Nephrol. 2008;19:1106-15 pubmed 出版商
Lee T, Yeh J, Friedman J, Yan B, Yang X, Yeh N, et al. A signal network involving coactivated NF-kappaB and STAT3 and altered p53 modulates BAX/BCL-XL expression and promotes cell survival of head and neck squamous cell carcinomas. Int J Cancer. 2008;122:1987-98 pubmed 出版商
Williams K, Young S, Negus A, Young L, Adams D, Afford S. C4b binding protein binds to CD154 preventing CD40 mediated cholangiocyte apoptosis: a novel link between complement and epithelial cell survival. PLoS ONE. 2007;2:e159 pubmed
Rosen D, Mercado Uribe I, Yang G, Bast R, Amin H, Lai R, et al. The role of constitutively active signal transducer and activator of transcription 3 in ovarian tumorigenesis and prognosis. Cancer. 2006;107:2730-40 pubmed
He H, Zhu T, Xie Y, Fan J, Kole S, Saxena S, et al. Pyrrolidine dithiocarbamate inhibits interleukin-6 signaling through impaired STAT3 activation and association with transcriptional coactivators in hepatocytes. J Biol Chem. 2006;281:31369-79 pubmed
Chang K, Wu M, Jones D, Chen F, Tseng Y. Activation of STAT3 in thymic epithelial tumours correlates with tumour type and clinical behaviour. J Pathol. 2006;210:224-33 pubmed
Cao F, Hata R, Zhu P, Ma Y, Tanaka J, Hanakawa Y, et al. Overexpression of SOCS3 inhibits astrogliogenesis and promotes maintenance of neural stem cells. J Neurochem. 2006;98:459-70 pubmed
Abou Sleymane G, Chalmel F, Helmlinger D, Lardenois A, Thibault C, Weber C, et al. Polyglutamine expansion causes neurodegeneration by altering the neuronal differentiation program. Hum Mol Genet. 2006;15:691-703 pubmed
Lai R, Rassidakis G, Lin Q, Atwell C, Medeiros L, Amin H. Jak3 activation is significantly associated with ALK expression in anaplastic large cell lymphoma. Hum Pathol. 2005;36:939-44 pubmed
Gagarin D, Yang Z, Butler J, Wimmer M, Du B, Cahan P, et al. Genomic profiling of acquired resistance to apoptosis in cells derived from human atherosclerotic lesions: potential role of STATs, cyclinD1, BAD, and Bcl-XL. J Mol Cell Cardiol. 2005;39:453-65 pubmed
Ahmed Choudhury J, Williams K, Young L, Adams D, Afford S. CD40 mediated human cholangiocyte apoptosis requires JAK2 dependent activation of STAT3 in addition to activation of JNK1/2 and ERK1/2. Cell Signal. 2006;18:456-68 pubmed
Gu F, Hata R, Ma Y, Tanaka J, Mitsuda N, Kumon Y, et al. Suppression of Stat3 promotes neurogenesis in cultured neural stem cells. J Neurosci Res. 2005;81:163-71 pubmed
产品信息
产品名称 :
Stat3(F-2)抗体
基因名称 :
STAT3
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-8019
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
Stat3
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), 酶联免疫吸附测定
表位 :
50-240(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。