Kang Y, Torrente L, Falzone A, Elkins C, Liu M, Asara J, et al. Cysteine dioxygenase 1 is a metabolic liability for non-small cell lung cancer. elife. 2019;8: pubmed 出版商

Douanne T, André Grégoire G, Thys A, Trillet K, Gavard J, Bidere N. CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1. Cell Rep. 2019;27:1657-1665.e4 pubmed 出版商

Zhou N, Gutierrez Uzquiza A, Zheng X, Chang R, Vogl D, Garfall A, et al. RUNX proteins desensitize multiple myeloma to lenalidomide via protecting IKZFs from degradation. Leukemia. 2019;: pubmed 出版商

Liu H, Lorenzini P, Zhang F, Xu S, Wong M, Zheng J, et al. Alternative splicing analysis in human monocytes and macrophages reveals MBNL1 as major regulator. Nucleic Acids Res. 2018;46:6069-6086 pubmed 出版商

Shin J, Choi D, Sohn K, Kim J, Im M, Lee Y, et al. Targeted deletion of Crif1 in mouse epidermis impairs skin homeostasis and hair morphogenesis. Sci Rep. 2017;7:44828 pubmed 出版商

Fang Y, Kong Y, Xi J, Zhu M, Zhu T, Jiang T, et al. Preclinical activity of MBM-5 in gastrointestinal cancer by inhibiting NEK2 kinase activity. Oncotarget. 2016;7:79327-79341 pubmed 出版商

Vanhoutte D, Schips T, Kwong J, Davis J, Tjondrokoesoemo A, Brody M, et al. Thrombospondin expression in myofibers stabilizes muscle membranes. elife. 2016;5: pubmed 出版商

Chen R, Wang S, Zhang Y, Hou R, Jiang J, Cui H. CD147 promotes cell motility via upregulation of p190-B RhoGAP in hepatocellular carcinoma. Cancer Cell Int. 2016;16:69 pubmed 出版商

Gómez Sánchez R, Yakhine Diop S, Bravo San Pedro J, Pizarro Estrella E, Rodríguez Arribas M, Climent V, et al. PINK1 deficiency enhances autophagy and mitophagy induction. Mol Cell Oncol. 2016;3:e1046579 pubmed 出版商

Singh V, Singh M, Gorantla S, Poluektova L, Maggirwar S. Smoothened Agonist Reduces Human Immunodeficiency Virus Type-1-Induced Blood-Brain Barrier Breakdown in Humanized Mice. Sci Rep. 2016;6:26876 pubmed 出版商

Kwon O, Kim K, Lee E, Kim M, Choi S, Li H, et al. Induction of MiR-21 by Stereotactic Body Radiotherapy Contributes to the Pulmonary Fibrotic Response. PLoS ONE. 2016;11:e0154942 pubmed 出版商

Watanabe Y, Papoutsoglou P, Maturi V, Tsubakihara Y, Hottiger M, Heldin C, et al. Regulation of Bone Morphogenetic Protein Signaling by ADP-ribosylation. J Biol Chem. 2016;291:12706-23 pubmed 出版商

Li R, Jin Z, Gao L, Liu P, Yang Z, Zhang D. Effective protein inhibition in intact mouse oocytes through peptide nanoparticle-mediated antibody transfection. Peerj. 2016;4:e1849 pubmed 出版商

Douanne T, Gavard J, Bidère N. The paracaspase MALT1 cleaves the LUBAC subunit HOIL1 during antigen receptor signaling. J Cell Sci. 2016;129:1775-80 pubmed 出版商

Gilormini M, Malesys C, Armandy E, Manas P, Guy J, Magne N, et al. Preferential targeting of cancer stem cells in the radiosensitizing effect of ABT-737 on HNSCC. Oncotarget. 2016;7:16731-44 pubmed 出版商

Hong J, Lee J, Chung I. Telomerase activates transcription of cyclin D1 gene through an interaction with NOL1. J Cell Sci. 2016;129:1566-79 pubmed 出版商

Fu Z, Wang L, Cui H, Peng J, Wang S, Geng J, et al. A novel small-molecule compound targeting CD147 inhibits the motility and invasion of hepatocellular carcinoma cells. Oncotarget. 2016;7:9429-47 pubmed 出版商

Di Magno L, Basile A, Coni S, Manni S, Sdruscia G, D Amico D, et al. The energy sensor AMPK regulates Hedgehog signaling in human cells through a unique Gli1 metabolic checkpoint. Oncotarget. 2016;7:9538-49 pubmed 出版商

Moudry P, Watanabe K, Wolanin K, Bartkova J, Wassing I, Watanabe S, et al. TOPBP1 regulates RAD51 phosphorylation and chromatin loading and determines PARP inhibitor sensitivity. J Cell Biol. 2016;212:281-8 pubmed 出版商

Goulielmaki M, Koustas E, Moysidou E, Vlassi M, Sasazuki T, Shirasawa S, et al. BRAF associated autophagy exploitation: BRAF and autophagy inhibitors synergise to efficiently overcome resistance of BRAF mutant colorectal cancer cells. Oncotarget. 2016;7:9188-221 pubmed 出版商

Sakamoto A, Akiyama Y, Shimada S, Zhu W, Yuasa Y, Tanaka S. DNA Methylation in the Exon 1 Region and Complex Regulation of Twist1 Expression in Gastric Cancer Cells. PLoS ONE. 2015;10:e0145630 pubmed 出版商

Brunati M, Perucca S, Han L, Cattaneo A, Consolato F, Andolfo A, et al. The serine protease hepsin mediates urinary secretion and polymerisation of Zona Pellucida domain protein uromodulin. elife. 2015;4:e08887 pubmed 出版商

Duffy D, Krstic A, Halasz M, Schwarzl T, Fey D, Iljin K, et al. Integrative omics reveals MYCN as a global suppressor of cellular signalling and enables network-based therapeutic target discovery in neuroblastoma. Oncotarget. 2015;6:43182-201 pubmed 出版商

Loiselle J, Tessier S, Sutherland L. Post-transcriptional regulation of Rbm5 expression in undifferentiated H9c2 myoblasts. In Vitro Cell Dev Biol Anim. 2016;52:327-36 pubmed 出版商

Chow C, Ebine K, Knab L, Bentrem D, Kumar K, Munshi H. Cancer Cell Invasion in Three-dimensional Collagen Is Regulated Differentially by Gα13 Protein and Discoidin Domain Receptor 1-Par3 Protein Signaling. J Biol Chem. 2016;291:1605-18 pubmed 出版商

Ambroise G, Portier A, Roders N, Arnoult D, Vazquez A. Subcellular localization of PUMA regulates its pro-apoptotic activity in Burkitt's lymphoma B cells. Oncotarget. 2015;6:38181-94 pubmed 出版商

Stockley J, Markert E, Zhou Y, Robson C, Elliott D, Lindberg J, et al. The RNA-binding protein Sam68 regulates expression and transcription function of the androgen receptor splice variant AR-V7. Sci Rep. 2015;5:13426 pubmed 出版商

Wolter S, Kloth C, Golombek M, Dittmar F, Försterling L, Seifert R. cCMP causes caspase-dependent apoptosis in mouse lymphoma cell lines. Biochem Pharmacol. 2015;98:119-31 pubmed 出版商

Sakabe I, Hu R, Jin L, Clarke R, Kasid U. TMEM33: a new stress-inducible endoplasmic reticulum transmembrane protein and modulator of the unfolded protein response signaling. Breast Cancer Res Treat. 2015;153:285-97 pubmed 出版商

Succoio M, Comegna M, D Ambrosio C, Scaloni A, Cimino F, Faraonio R. Proteomic analysis reveals novel common genes modulated in both replicative and stress-induced senescence. J Proteomics. 2015;128:18-29 pubmed 出版商

Fink E, Mannava S, Bagati A, Bianchi Smiraglia A, Nair J, Moparthy K, et al. Mitochondrial thioredoxin reductase regulates major cytotoxicity pathways of proteasome inhibitors in multiple myeloma cells. Leukemia. 2016;30:104-11 pubmed 出版商

Nagaoka K, Matoba T, Mao Y, Nakano Y, Ikeda G, Egusa S, et al. A New Therapeutic Modality for Acute Myocardial Infarction: Nanoparticle-Mediated Delivery of Pitavastatin Induces Cardioprotection from Ischemia-Reperfusion Injury via Activation of PI3K/Akt Pathway and Anti-Inflammation in a Rat Model. PLoS ONE. 2015;10:e0132451 pubmed 出版商

Duan H, Li Y, Lim H, Wang W. Identification of 5-nitrofuran-2-amide derivatives that induce apoptosis in triple negative breast cancer cells by activating C/EBP-homologous protein expression. Bioorg Med Chem. 2015;23:4514-21 pubmed 出版商

Condelli V, Maddalena F, Sisinni L, Lettini G, Matassa D, Piscazzi A, et al. Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma. Oncotarget. 2015;6:22298-309 pubmed

Kiebala M, Singh M, Piepenbrink M, Qiu X, Kobie J, Maggirwar S. Platelet Activation in Human Immunodeficiency Virus Type-1 Patients Is Not Altered with Cocaine Abuse. PLoS ONE. 2015;10:e0130061 pubmed 出版商

Petroni M, Sardina F, Heil C, Sahún Roncero M, Colicchia V, Veschi V, et al. The MRN complex is transcriptionally regulated by MYCN during neural cell proliferation to control replication stress. Cell Death Differ. 2016;23:197-206 pubmed 出版商

Nagata T, Yasukawa H, Kyogoku S, Oba T, Takahashi J, Nohara S, et al. Cardiac-Specific SOCS3 Deletion Prevents In Vivo Myocardial Ischemia Reperfusion Injury through Sustained Activation of Cardioprotective Signaling Molecules. PLoS ONE. 2015;10:e0127942 pubmed 出版商

Cicchini C, de Nonno V, Battistelli C, Cozzolino A, De Santis Puzzonia M, Ciafrè S, et al. Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29. Biochim Biophys Acta. 2015;1849:919-29 pubmed 出版商

Bhatt D, Puig K, Gorr M, Wold L, Combs C. A pilot study to assess effects of long-term inhalation of airborne particulate matter on early Alzheimer-like changes in the mouse brain. PLoS ONE. 2015;10:e0127102 pubmed 出版商

Mauro Lizcano M, Esteban Martínez L, Seco E, Serrano Puebla A, García Ledo L, Figueiredo Pereira C, et al. New method to assess mitophagy flux by flow cytometry. Autophagy. 2015;11:833-43 pubmed 出版商

Min K, Liggett J, Silva G, Wu W, Wang R, Shen R, et al. NAG-1/GDF15 accumulates in the nucleus and modulates transcriptional regulation of the Smad pathway. Oncogene. 2016;35:377-88 pubmed 出版商

Chong L, Hsu Y, Lee T, Lin Y, Chiu Y, Yang K, et al. Fluvastatin attenuates hepatic steatosis-induced fibrogenesis in rats through inhibiting paracrine effect of hepatocyte on hepatic stellate cells. BMC Gastroenterol. 2015;15:22 pubmed 出版商

Shi Y, Chen J, Karner C, Long F. Hedgehog signaling activates a positive feedback mechanism involving insulin-like growth factors to induce osteoblast differentiation. Proc Natl Acad Sci U S A. 2015;112:4678-83 pubmed 出版商

Rappa G, Green T, Karbanová J, Corbeil D, Lorico A. Tetraspanin CD9 determines invasiveness and tumorigenicity of human breast cancer cells. Oncotarget. 2015;6:7970-91 pubmed

Grabner B, Schramek D, Mueller K, Moll H, Svinka J, Hoffmann T, et al. Disruption of STAT3 signalling promotes KRAS-induced lung tumorigenesis. Nat Commun. 2015;6:6285 pubmed 出版商

Jeong H, Gil N, Lee H, Cho S, Kim K, Chun K, et al. Timely Degradation of Wip1 Phosphatase by APC/C Activator Protein Cdh1 is Necessary for Normal Mitotic Progression. J Cell Biochem. 2015;116:1602-12 pubmed 出版商

Xue J, Chen Y, Wu Y, Wang Z, Zhou A, Zhang S, et al. Tumour suppressor TRIM33 targets nuclear β-catenin degradation. Nat Commun. 2015;6:6156 pubmed 出版商

Karner C, Esen E, Okunade A, Patterson B, Long F. Increased glutamine catabolism mediates bone anabolism in response to WNT signaling. J Clin Invest. 2015;125:551-62 pubmed 出版商

Hong A, Lee J, Chung K. Ubiquitin-specific protease 22 (USP22) positively regulates RCAN1 protein levels through RCAN1 de-ubiquitination. J Cell Physiol. 2015;230:1651-60 pubmed 出版商

Gonzalez Granado J, Navarro Puche A, Molina Sánchez P, Blanco Berrocal M, Viana R, Font de Mora J, et al. Sorting nexin 6 enhances lamin a synthesis and incorporation into the nuclear envelope. PLoS ONE. 2014;9:e115571 pubmed 出版商

Kim T, Kim H, Kang Y, Yoon S, Lee J, Choi W, et al. Psammaplin A induces Sirtuin 1-dependent autophagic cell death in doxorubicin-resistant MCF-7/adr human breast cancer cells and xenografts. Biochim Biophys Acta. 2015;1850:401-10 pubmed 出版商

Wang S, Cui H, Liu Y, Zhao P, Zhang Y, Fu Z, et al. CD147 promotes Src-dependent activation of Rac1 signaling through STAT3/DOCK8 during the motility of hepatocellular carcinoma cells. Oncotarget. 2015;6:243-57 pubmed

Liu F, Shen W, Qiu H, Hu X, Zhang C, Chu T. Prostate cancer cells induce osteoblastic differentiation via semaphorin 3A. Prostate. 2015;75:370-80 pubmed 出版商

Lee K, Yeo S, Sung C, Kim S. Twist1 is a key regulator of cancer-associated fibroblasts. Cancer Res. 2015;75:73-85 pubmed 出版商

Hock A, Vigneron A, Vousden K. Ubiquitin-specific peptidase 42 (USP42) functions to deubiquitylate histones and regulate transcriptional activity. J Biol Chem. 2014;289:34862-70 pubmed 出版商

Zhao X, Zhu L, Chang Q, Jiang C, You Y, Luo T, et al. C-type lectin receptor dectin-3 mediates trehalose 6,6'-dimycolate (TDM)-induced Mincle expression through CARD9/Bcl10/MALT1-dependent nuclear factor (NF)-κB activation. J Biol Chem. 2014;289:30052-62 pubmed 出版商

Ginet V, Pittet M, Rummel C, Osterheld M, Meuli R, Clarke P, et al. Dying neurons in thalamus of asphyxiated term newborns and rats are autophagic. Ann Neurol. 2014;76:695-711 pubmed 出版商

de Souza E, Meirelles G, Godoy B, Perez A, Smetana J, Doxsey S, et al. Characterization of the human NEK7 interactome suggests catalytic and regulatory properties distinct from those of NEK6. J Proteome Res. 2014;13:4074-90 pubmed 出版商

Mostocotto C, Carbone M, Battistelli C, Ciotti A, Amati P, Maione R. Poly(ADP-ribosyl)ation is required to modulate chromatin changes at c-MYC promoter during emergence from quiescence. PLoS ONE. 2014;9:e102575 pubmed 出版商

Patel A, Burton D, Halvorsen K, Balkan W, Reiner T, Perez Stable C, et al. MutT Homolog 1 (MTH1) maintains multiple KRAS-driven pro-malignant pathways. Oncogene. 2015;34:2586-96 pubmed 出版商

Gaillard F, Kuny S, Sauve Y. Retinal distribution of Disabled-1 in a diurnal murine rodent, the Nile grass rat Arvicanthis niloticus. Exp Eye Res. 2014;125:236-43 pubmed 出版商

Ranjan R, Deng J, Chung S, Lee Y, Park G, Xiao L, et al. The transcription factor nuclear factor of activated T cells c3 modulates the function of macrophages in sepsis. J Innate Immun. 2014;6:754-64 pubmed 出版商

Liu Q, Boudot A, Ni J, Hennessey T, Beauparlant S, Rajabi H, et al. Cyclin D1 and C/EBP? LAP1 operate in a common pathway to promote mammary epithelial cell differentiation. Mol Cell Biol. 2014;34:3168-79 pubmed 出版商

Erdozain A, Morentin B, Bedford L, King E, Tooth D, Brewer C, et al. Alcohol-related brain damage in humans. PLoS ONE. 2014;9:e93586 pubmed 出版商

Karpurapu M, Ranjan R, Deng J, Chung S, Lee Y, Xiao L, et al. Krüppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation. PLoS ONE. 2014;9:e93362 pubmed 出版商

Gilan O, Diesch J, Amalia M, Jastrzebski K, Chueh A, Verrills N, et al. PR55?-containing protein phosphatase 2A complexes promote cancer cell migration and invasion through regulation of AP-1 transcriptional activity. Oncogene. 2015;34:1333-9 pubmed 出版商

Nakajima W, Hicks M, Tanaka N, Krystal G, Harada H. Noxa determines localization and stability of MCL-1 and consequently ABT-737 sensitivity in small cell lung cancer. Cell Death Dis. 2014;5:e1052 pubmed 出版商

Vittori A, Breda C, Repici M, Orth M, Roos R, Outeiro T, et al. Copy-number variation of the neuronal glucose transporter gene SLC2A3 and age of onset in Huntington's disease. Hum Mol Genet. 2014;23:3129-37 pubmed 出版商

Vellaichamy E, Das S, Subramanian U, Maeda N, Pandey K. Genetically altered mutant mouse models of guanylyl cyclase/natriuretic peptide receptor-A exhibit the cardiac expression of proinflammatory mediators in a gene-dose-dependent manner. Endocrinology. 2014;155:1045-56 pubmed 出版商

Loiselle J, Sutherland L. Differential downregulation of Rbm5 and Rbm10 during skeletal and cardiac differentiation. In Vitro Cell Dev Biol Anim. 2014;50:331-9 pubmed 出版商

Lee J, Park J, Kwon O, Kim H, Fornace A, Cha H. Off-target response of a Wip1 chemical inhibitor in skin keratinocytes. J Dermatol Sci. 2014;73:125-34 pubmed 出版商

Shats I, Gatza M, Liu B, Angus S, You L, Nevins J. FOXO transcription factors control E2F1 transcriptional specificity and apoptotic function. Cancer Res. 2013;73:6056-67 pubmed 出版商

O Dell L, Natividad L, Pipkin J, Roman F, Torres I, Jurado J, et al. Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes. Addict Biol. 2014;19:1006-19 pubmed 出版商

Pavlova N, Pallasch C, Elia A, Braun C, Westbrook T, Hemann M, et al. A role for PVRL4-driven cell-cell interactions in tumorigenesis. elife. 2013;2:e00358 pubmed 出版商

Brennan G, Jimenez Mateos E, McKiernan R, Engel T, Tzivion G, Henshall D. Transgenic overexpression of 14-3-3 zeta protects hippocampus against endoplasmic reticulum stress and status epilepticus in vivo. PLoS ONE. 2013;8:e54491 pubmed 出版商

Lei K, Chen L, Georgiou E, Sooranna S, Khanjani S, Brosens J, et al. Progesterone acts via the nuclear glucocorticoid receptor to suppress IL-1?-induced COX-2 expression in human term myometrial cells. PLoS ONE. 2012;7:e50167 pubmed 出版商

Blakemore L, Boes C, Cordell R, Manson M. Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage. Carcinogenesis. 2013;34:351-60 pubmed 出版商

An C, Dong Y, Hagiwara N. Genome-wide mapping of Sox6 binding sites in skeletal muscle reveals both direct and indirect regulation of muscle terminal differentiation by Sox6. BMC Dev Biol. 2011;11:59 pubmed 出版商

Rossi M, Carbone M, Mostocotto C, Mancone C, Tripodi M, Maione R, et al. Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity. J Biol Chem. 2009;284:31616-24 pubmed 出版商

Bengoechea Alonso M, Punga T, Ericsson J. Hyperphosphorylation regulates the activity of SREBP1 during mitosis. Proc Natl Acad Sci U S A. 2005;102:11681-6 pubmed

Lima T, Guimarães D, Sponton C, Bajgelman M, Palameta S, Toscaro J, et al. Essential role of PGC-1α/PPARβ axis in Ucp3 gene induction. J Physiol. 2019;: pubmed 出版商

Xu D, Li X, Shao F, Lv G, Lv H, Lee J, et al. The protein kinase activity of fructokinase A specifies the antioxidant responses of tumor cells by phosphorylating p62. Sci Adv. 2019;5:eaav4570 pubmed 出版商

Yoo S, Lee C, An H, Lee J, Lee H, Kang H, et al. RSK2-Mediated ELK3 Activation Enhances Cell Transformation and Breast Cancer Cell Growth by Regulation of c-fos Promoter Activity. Int J Mol Sci. 2019;20: pubmed 出版商

Lin K, Qiang W, Zhu M, Ding Y, Shi Q, Chen X, et al. Mammalian Pum1 and Pum2 Control Body Size via Translational Regulation of the Cell Cycle Inhibitor Cdkn1b. Cell Rep. 2019;26:2434-2450.e6 pubmed 出版商

Kizilyer A, Singh M, Singh V, Suwunnakorn S, Palis J, Maggirwar S. Inhibition of Tropomyosin Receptor Kinase A Signaling Negatively Regulates Megakaryopoiesis and induces Thrombopoiesis. Sci Rep. 2019;9:2781 pubmed 出版商

Wang J, Chan B, Tong M, Paung Y, Jo U, MARTIN D, et al. Prolyl isomerization of FAAP20 catalyzed by PIN1 regulates the Fanconi anemia pathway. PLoS Genet. 2019;15:e1007983 pubmed 出版商

Messenger Z, Hall J, Jima D, House J, Tam H, Tokarz D, et al. C/EBPβ deletion in oncogenic Ras skin tumors is a synthetic lethal event. Cell Death Dis. 2018;9:1054 pubmed 出版商

Fink E, Moparthy S, Bagati A, Bianchi Smiraglia A, Lipchick B, Wolff D, et al. XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response. Cell Rep. 2018;25:212-223.e4 pubmed 出版商

Hartleben G, Muller C, Kramer A, Schimmel H, Zidek L, Dornblut C, et al. Tuberous sclerosis complex is required for tumor maintenance in MYC-driven Burkitt's lymphoma. EMBO J. 2018;37: pubmed 出版商

Karnati S, Oruqaj G, Janga H, Tumpara S, Colasante C, Van Veldhoven P, et al. PPARα-mediated peroxisome induction compensates PPARγ-deficiency in bronchiolar club cells. PLoS ONE. 2018;13:e0203466 pubmed 出版商

Labisso W, Raulin A, Nwidu L, Kocon A, Wayne D, Erdozain A, et al. The Loss of α- and β-Tubulin Proteins Are a Pathological Hallmark of Chronic Alcohol Consumption and Natural Brain Ageing. Brain Sci. 2018;8: pubmed 出版商

Leikina E, Gamage D, Prasad V, Goykhberg J, Crowe M, Diao J, et al. Myomaker and Myomerger Work Independently to Control Distinct Steps of Membrane Remodeling during Myoblast Fusion. Dev Cell. 2018;46:767-780.e7 pubmed 出版商

Simandi Z, Pajer K, Károlyi K, Sieler T, Jiang L, Kolostyak Z, et al. Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons. J Neurosci. 2018;38:7683-7700 pubmed 出版商

Li M, Xu X, Chang C, Zheng L, Shen B, Liu Y. SUMO2 conjugation of PCNA facilitates chromatin remodeling to resolve transcription-replication conflicts. Nat Commun. 2018;9:2706 pubmed 出版商

Davis T, Yang M, Schell M, Wang H, Ma L, Pledger W, et al. PTPRS Regulates Colorectal Cancer RAS Pathway Activity by Inactivating Erk and Preventing Its Nuclear Translocation. Sci Rep. 2018;8:9296 pubmed 出版商

Meier Soelch J, Jurida L, Weber A, Newel D, Kim J, Braun T, et al. RNAi-Based Identification of Gene-Specific Nuclear Cofactor Networks Regulating Interleukin-1 Target Genes. Front Immunol. 2018;9:775 pubmed 出版商

Dejos C, Kuny S, Han W, Capel H, Lemieux H, Sauvé Y. Photoreceptor-induced RPE phagolysosomal maturation defects in Stargardt-like Maculopathy (STGD3). Sci Rep. 2018;8:5944 pubmed 出版商

Fu J, Huang D, Yuan F, Xie N, Li Q, Sun X, et al. TRAF-interacting protein with forkhead-associated domain (TIFA) transduces DNA damage-induced activation of NF-κB. J Biol Chem. 2018;293:7268-7280 pubmed 出版商

Kuo W, Ho T, Chiang S, Pai P, Lin J, Lin D, et al. Rab9-dependent autophagy is required for the IGF-IIR triggering mitophagy to eliminate damaged mitochondria. J Cell Physiol. 2018;233:7080-7091 pubmed 出版商

Pasini A, Brand O, Jenkins G, Knox A, Pang L. Suberanilohydroxamic acid prevents TGF-β1-induced COX-2 repression in human lung fibroblasts post-transcriptionally by TIA-1 downregulation. Biochim Biophys Acta Gene Regul Mech. 2018;1861:463-472 pubmed 出版商

Karpurapu M, Lee Y, Qian Z, Wen J, Ballinger M, Rusu L, et al. Inhibition of nuclear factor of activated T cells (NFAT) c3 activation attenuates acute lung injury and pulmonary edema in murine models of sepsis. Oncotarget. 2018;9:10606-10620 pubmed 出版商

Pilling A, Kim J, Estrada Bernal A, Zhou Q, Le A, Singleton K, et al. ALK is a critical regulator of the MYC-signaling axis in ALK positive lung cancer. Oncotarget. 2018;9:8823-8835 pubmed 出版商

Dodson M, Liu P, Jiang T, Ambrose A, Luo G, Rojo de la Vega M, et al. Increased O-GlcNAcylation of SNAP29 Drives Arsenic-Induced Autophagic Dysfunction. Mol Cell Biol. 2018;38: pubmed 出版商

Oerlemans R, Berkers C, Assaraf Y, Scheffer G, Peters G, Verbrugge S, et al. Proteasome inhibition and mechanism of resistance to a synthetic, library-based hexapeptide. Invest New Drugs. 2018;36:797-809 pubmed 出版商

Miyai T, Takano J, Endo T, Kawakami E, Agata Y, Motomura Y, et al. Three-step transcriptional priming that drives the commitment of multipotent progenitors toward B cells. Genes Dev. 2018;32:112-126 pubmed 出版商

Tögel L, Nightingale R, Wu R, Chueh A, Al Obaidi S, Luk I, et al. DUSP5 is methylated in CIMP-high colorectal cancer but is not a major regulator of intestinal cell proliferation and tumorigenesis. Sci Rep. 2018;8:1767 pubmed 出版商

Eldakhakhny S, Zhou Q, Crosbie E, Sayan B. Human papillomavirus E7 induces p63 expression to modulate DNA damage response. Cell Death Dis. 2018;9:127 pubmed 出版商

Dilworth D, Gudavicius G, Xu X, Boyce A, O Sullivan C, Serpa J, et al. The prolyl isomerase FKBP25 regulates microtubule polymerization impacting cell cycle progression and genomic stability. Nucleic Acids Res. 2018;46:2459-2478 pubmed 出版商

Tian W, Rojo de la Vega M, Schmidlin C, Ooi A, Zhang D. Kelch-like ECH-associated protein 1 (KEAP1) differentially regulates nuclear factor erythroid-2-related factors 1 and 2 (NRF1 and NRF2). J Biol Chem. 2018;293:2029-2040 pubmed 出版商

Yoo L, Chung K. The ubiquitin E3 ligase CHIP promotes proteasomal degradation of the serine/threonine protein kinase PINK1 during staurosporine-induced cell death. J Biol Chem. 2018;293:1286-1297 pubmed 出版商

Li H, Liang J, Kuo Y, Lee H, Calkins M, Chang H, et al. miR-105/93-3p promotes chemoresistance and circulating miR-105/93-3p acts as a diagnostic biomarker for triple negative breast cancer. Breast Cancer Res. 2017;19:133 pubmed 出版商

Sundqvist A, Morikawa M, Ren J, Vasilaki E, Kawasaki N, Kobayashi M, et al. JUNB governs a feed-forward network of TGF? signaling that aggravates breast cancer invasion. Nucleic Acids Res. 2017;: pubmed 出版商

Sancisi V, Manzotti G, Gugnoni M, Rossi T, Gandolfi G, Gobbi G, et al. RUNX2 expression in thyroid and breast cancer requires the cooperation of three non-redundant enhancers under the control of BRD4 and c-JUN. Nucleic Acids Res. 2017;45:11249-11267 pubmed 出版商

Tang L, Wang M, Liu D, Gong M, Ying Q, Ye S. Sp5 induces the expression of Nanog to maintain mouse embryonic stem cell self-renewal. PLoS ONE. 2017;12:e0185714 pubmed 出版商

Penha R, Sepe R, De Martino M, Esposito F, Pellecchia S, Raia M, et al. Role of Dicer1 in thyroid cell proliferation and differentiation. Cell Cycle. 2017;16:2282-2289 pubmed 出版商

Yanda M, Liu Q, Cebotaru V, Guggino W, Cebotaru L. Histone deacetylase 6 inhibition reduces cysts by decreasing cAMP and Ca2+ in knock-out mouse models of polycystic kidney disease. J Biol Chem. 2017;292:17897-17908 pubmed 出版商

Gamage D, Leikina E, Quinn M, Ratinov A, Chernomordik L, Millay D. Insights into the localization and function of myomaker during myoblast fusion. J Biol Chem. 2017;292:17272-17289 pubmed 出版商

Wang M, Tang L, Liu D, Ying Q, Ye S. The transcription factor Gbx2 induces expression of Kruppel-like factor 4 to maintain and induce naïve pluripotency of embryonic stem cells. J Biol Chem. 2017;292:17121-17128 pubmed 出版商

Johnson N, Brezinova J, Stephens E, Burbridge E, Freeman M, Adrain C, et al. Quantitative proteomics screen identifies a substrate repertoire of rhomboid protease RHBDL2 in human cells and implicates it in epithelial homeostasis. Sci Rep. 2017;7:7283 pubmed 出版商

Nikhil K, Shah K. The Cdk5-Mcl-1 axis promotes mitochondrial dysfunction and neurodegeneration in a model of Alzheimer's disease. J Cell Sci. 2017;130:3023-3039 pubmed 出版商

Duan H, Li Y, Arora D, Xu D, Lim H, Wang W. Discovery of a Benzamide Derivative That Protects Pancreatic β-Cells against Endoplasmic Reticulum Stress. J Med Chem. 2017;60:6191-6204 pubmed 出版商

Keogh C, Scholz C, Rodriguez J, Selfridge A, von Kriegsheim A, Cummins E. Carbon dioxide-dependent regulation of NF-?B family members RelB and p100 gives molecular insight into CO2-dependent immune regulation. J Biol Chem. 2017;292:11561-11571 pubmed 出版商

Esteban Martínez L, Sierra Filardi E, McGreal R, Salazar Roa M, Mariño G, Seco E, et al. Programmed mitophagy is essential for the glycolytic switch during cell differentiation. EMBO J. 2017;36:1688-1706 pubmed 出版商

Kim J, Jiang J, Badawi M, Schmittgen T. miR-221 regulates CD44 in hepatocellular carcinoma through the PI3K-AKT-mTOR pathway. Biochem Biophys Res Commun. 2017;487:709-715 pubmed 出版商

Coni S, Mancuso A, Di Magno L, Sdruscia G, Manni S, Serrao S, et al. Selective targeting of HDAC1/2 elicits anticancer effects through Gli1 acetylation in preclinical models of SHH Medulloblastoma. Sci Rep. 2017;7:44079 pubmed 出版商

Teng Y, Ren Y, Hu X, Mu J, Samykutty A, Zhuang X, et al. MVP-mediated exosomal sorting of miR-193a promotes colon cancer progression. Nat Commun. 2017;8:14448 pubmed 出版商

Wang J, Nikhil K, Viccaro K, Chang L, White J, Shah K. Phosphorylation-dependent regulation of ALDH1A1 by Aurora kinase A: insights on their synergistic relationship in pancreatic cancer. BMC Biol. 2017;15:10 pubmed 出版商

Biehs R, Steinlage M, Barton O, Juhasz S, Künzel J, Spies J, et al. DNA Double-Strand Break Resection Occurs during Non-homologous End Joining in G1 but Is Distinct from Resection during Homologous Recombination. Mol Cell. 2017;65:671-684.e5 pubmed 出版商

Qi Z, Li Y, Zhao B, Xu C, Liu Y, Li H, et al. BMP restricts stemness of intestinal Lgr5+ stem cells by directly suppressing their signature genes. Nat Commun. 2017;8:13824 pubmed 出版商

Marmisolle I, Martínez J, Liu J, Mastrogiovanni M, Fergusson M, Rovira I, et al. Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation. Arch Biochem Biophys. 2017;613:12-22 pubmed 出版商

Sarkar D, Singh S. Effect of neonatal hypothyroidism on prepubertal mouse testis in relation to thyroid hormone receptor alpha 1 (THR?1). Gen Comp Endocrinol. 2017;251:109-120 pubmed 出版商

Nakamura H, Nagasaka K, Kawana K, Taguchi A, Uehara Y, Yoshida M, et al. Expression of Par3 polarity protein correlates with poor prognosis in ovarian cancer. BMC Cancer. 2016;16:897 pubmed

Jugé R, Breugnot J, Da Silva C, Bordes S, Closs B, Aouacheria A. Quantification and Characterization of UVB-Induced Mitochondrial Fragmentation in Normal Primary Human Keratinocytes. Sci Rep. 2016;6:35065 pubmed 出版商

Nakajima W, Sharma K, Lee J, Maxim N, Hicks M, Vu T, et al. DNA damaging agent-induced apoptosis is regulated by MCL-1 phosphorylation and degradation mediated by the Noxa/MCL-1/CDK2 complex. Oncotarget. 2016;7:36353-36365 pubmed 出版商

Di Girolamo D, Ambrosio R, De Stefano M, Mancino G, Porcelli T, Luongo C, et al. Reciprocal interplay between thyroid hormone and microRNA-21 regulates hedgehog pathway-driven skin tumorigenesis. J Clin Invest. 2016;126:2308-20 pubmed 出版商

Jiang C, Zhou Z, Quan Y, Zhang S, Wang T, Zhao X, et al. CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection. Cell Rep. 2016;14:2389-401 pubmed 出版商

Chang H, Yi B, Ma R, Zhang X, Zhao H, Xi Y. CRISPR/cas9, a novel genomic tool to knock down microRNA in vitro and in vivo. Sci Rep. 2016;6:22312 pubmed 出版商

In K, Zaini M, Müller C, Warren A, von Lindern M, Calkhoven C. Shwachman-Bodian-Diamond syndrome (SBDS) protein deficiency impairs translation re-initiation from C/EBPα and C/EBPβ mRNAs. Nucleic Acids Res. 2016;44:4134-46 pubmed 出版商

Zheng M, Turton K, Zhu F, Li Y, Grindle K, Annis D, et al. A mix of S and ΔS variants of STAT3 enable survival of activated B-cell-like diffuse large B-cell lymphoma cells in culture. Oncogenesis. 2016;4:e184 pubmed 出版商

Fan L, Peng G, Sahgal N, Fazli L, Gleave M, Zhang Y, et al. Regulation of c-Myc expression by the histone demethylase JMJD1A is essential for prostate cancer cell growth and survival. Oncogene. 2016;35:2441-52 pubmed 出版商

Law J, Salla M, Zare A, Wong Y, Luong L, Volodko N, et al. Modulator of apoptosis 1 (MOAP-1) is a tumor suppressor protein linked to the RASSF1A protein. J Biol Chem. 2015;290:24100-18 pubmed 出版商

Huang T, Zhang K, Sun L, Xue X, Zhang C, Shu Z, et al. Body protective compound-157 enhances alkali-burn wound healing in vivo and promotes proliferation, migration, and angiogenesis in vitro. Drug Des Devel Ther. 2015;9:2485-99 pubmed 出版商

Paugh S, Bonten E, Savic D, Ramsey L, Thierfelder W, Gurung P, et al. NALP3 inflammasome upregulation and CASP1 cleavage of the glucocorticoid receptor cause glucocorticoid resistance in leukemia cells. Nat Genet. 2015;47:607-14 pubmed 出版商

Wang H, Rosati B, Gordon C, Valiunas V, McKinnon D, Cohen I, et al. Inhibition of histone deacetylase (HDAC) by 4-phenylbutyrate results in increased junctional conductance between rat corpora smooth muscle cells. Front Pharmacol. 2015;6:9 pubmed 出版商

Choudhury Y, Yang Z, Ahmad I, Nixon C, Salt I, Leung H. AMP-activated protein kinase (AMPK) as a potential therapeutic target independent of PI3K/Akt signaling in prostate cancer. Oncoscience. 2014;1:446-56 pubmed

Van de Looij Y, Ginet V, Chatagner A, Toulotte A, Somm E, Hüppi P, et al. Lactoferrin during lactation protects the immature hypoxic-ischemic rat brain. Ann Clin Transl Neurol. 2014;1:955-67 pubmed 出版商

Ferraro A, Boni T, Pintzas A. EZH2 regulates cofilin activity and colon cancer cell migration by targeting ITGA2 gene. PLoS ONE. 2014;9:e115276 pubmed 出版商

Lo U, Selvaraj V, Plane J, Chechneva O, Otsu K, Deng W. p38α (MAPK14) critically regulates the immunological response and the production of specific cytokines and chemokines in astrocytes. Sci Rep. 2014;4:7405 pubmed 出版商

Dentice M, Ambrosio R, Damiano V, Sibilio A, Luongo C, Guardiola O, et al. Intracellular inactivation of thyroid hormone is a survival mechanism for muscle stem cell proliferation and lineage progression. Cell Metab. 2014;20:1038-48 pubmed 出版商

Unbekandt M, Croft D, Crighton D, Mezna M, McArthur D, McConnell P, et al. A novel small-molecule MRCK inhibitor blocks cancer cell invasion. Cell Commun Signal. 2014;12:54 pubmed 出版商

Lai D, Liu S, Karlsson A, Lee W, Wang K, Chen Y, et al. The novel Aryl hydrocarbon receptor inhibitor biseugenol inhibits gastric tumor growth and peritoneal dissemination. Oncotarget. 2014;5:7788-804 pubmed

De Nicola F, Catena V, Rinaldo C, Bruno T, Iezzi S, Sorino C, et al. HIPK2 sustains apoptotic response by phosphorylating Che-1/AATF and promoting its degradation. Cell Death Dis. 2014;5:e1414 pubmed 出版商

Cho B, Cho H, Kim H, Jeong J, Park S, Hwang E, et al. CDK5-dependent inhibitory phosphorylation of Drp1 during neuronal maturation. Exp Mol Med. 2014;46:e105 pubmed 出版商

Labrecque M, Takhar M, Jagdeo J, Tam K, Chiu C, Wang T, et al. A TRIP230-retinoblastoma protein complex regulates hypoxia-inducible factor-1?-mediated transcription and cancer cell invasion. PLoS ONE. 2014;9:e99214 pubmed 出版商

Shaiken T, Opekun A. Dissecting the cell to nucleus, perinucleus and cytosol. Sci Rep. 2014;4:4923 pubmed 出版商

Jørgensen A, Young J, Nielsen J, Joensen U, Toft B, Rajpert De Meyts E, et al. Hanging drop cultures of human testis and testis cancer samples: a model used to investigate activin treatment effects in a preserved niche. Br J Cancer. 2014;110:2604-14 pubmed 出版商

Kuo W, Sharifi M, Lingen M, Ahmed O, Liu J, Nagilla M, et al. p62/SQSTM1 accumulation in squamous cell carcinoma of head and neck predicts sensitivity to phosphatidylinositol 3-kinase pathway inhibitors. PLoS ONE. 2014;9:e90171 pubmed 出版商

Garcia Castro B, Alvarez Zavala M, Riveros Magaña A, Ortiz Lazareno P, Ratkovich González S, Hernandez Flores G, et al. Restoration of WNT4 inhibits cell growth in leukemia-derived cell lines. BMC Cancer. 2013;13:557 pubmed 出版商

Dubovsky J, Chappell D, Harrington B, Agrawal K, Andritsos L, Flynn J, et al. Lymphocyte cytosolic protein 1 is a chronic lymphocytic leukemia membrane-associated antigen critical to niche homing. Blood. 2013;122:3308-16 pubmed 出版商

Redon S, Zemp I, Lingner J. A three-state model for the regulation of telomerase by TERRA and hnRNPA1. Nucleic Acids Res. 2013;41:9117-28 pubmed 出版商

Torres O, Walker E, Beas B, O Dell L. Female rats display enhanced rewarding effects of ethanol that are hormone dependent. Alcohol Clin Exp Res. 2014;38:108-15 pubmed 出版商

Williams Karnesky R, Sandau U, Lusardi T, Lytle N, Farrell J, Pritchard E, et al. Epigenetic changes induced by adenosine augmentation therapy prevent epileptogenesis. J Clin Invest. 2013;123:3552-63 pubmed 出版商

Abdelbaqi K, Di Paola D, Rampakakis E, Zannis Hadjopoulos M. Ku protein levels, localization and association to replication origins in different stages of breast tumor progression. J Cancer. 2013;4:358-70 pubmed 出版商

Coni S, Antonucci L, D Amico D, Di Magno L, Infante P, De Smaele E, et al. Gli2 acetylation at lysine 757 regulates hedgehog-dependent transcriptional output by preventing its promoter occupancy. PLoS ONE. 2013;8:e65718 pubmed 出版商

Shields M, Ebine K, Sahai V, Kumar K, Siddiqui K, Hwang R, et al. Snail cooperates with KrasG12D to promote pancreatic fibrosis. Mol Cancer Res. 2013;11:1078-87 pubmed 出版商

Dangi Garimella S, Sahai V, Ebine K, Kumar K, Munshi H. Three-dimensional collagen I promotes gemcitabine resistance in vitro in pancreatic cancer cells through HMGA2-dependent histone acetyltransferase expression. PLoS ONE. 2013;8:e64566 pubmed 出版商

Lei X, Bone R, Ali T, Wohltmann M, Gai Y, Goodwin K, et al. Genetic modulation of islet ?-cell iPLA?? expression provides evidence for its impact on ?-cell apoptosis and autophagy. Islets. 2013;5:29-44 pubmed 出版商

Ambrosio R, Damiano V, Sibilio A, De Stefano M, Avvedimento V, Salvatore D, et al. Epigenetic control of type 2 and 3 deiodinases in myogenesis: role of Lysine-specific Demethylase enzyme and FoxO3. Nucleic Acids Res. 2013;41:3551-62 pubmed 出版商

Mussnich P, D Angelo D, Leone V, Croce C, Fusco A. The High Mobility Group A proteins contribute to thyroid cell transformation by regulating miR-603 and miR-10b expression. Mol Oncol. 2013;7:531-42 pubmed 出版商

Mei Y, Bian C, Li J, Du Z, Zhou H, Yang Z, et al. miR-21 modulates the ERK-MAPK signaling pathway by regulating SPRY2 expression during human mesenchymal stem cell differentiation. J Cell Biochem. 2013;114:1374-84 pubmed 出版商

Brody M, Hacker T, Patel J, Feng L, Sadoshima J, Tevosian S, et al. Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy. PLoS ONE. 2012;7:e51621 pubmed 出版商

Bejjani A, Choi M, Cassidy L, Collins D, O Brien J, Murray T, et al. RB116: an RB1+ retinoblastoma cell line expressing primitive markers. Mol Vis. 2012;18:2805-13 pubmed

Polachini G, Sobral L, Mercante A, Paes Leme A, Xavier F, Henrique T, et al. Proteomic approaches identify members of cofilin pathway involved in oral tumorigenesis. PLoS ONE. 2012;7:e50517 pubmed 出版商

Jiwaji M, Daly R, Gibriel A, Barkess G, McLean P, Yang J, et al. Unique reporter-based sensor platforms to monitor signalling in cells. PLoS ONE. 2012;7:e50521 pubmed 出版商

Repici M, Straatman K, Balduccio N, Enguita F, Outeiro T, Giorgini F. Parkinson's disease-associated mutations in DJ-1 modulate its dimerization in living cells. J Mol Med (Berl). 2013;91:599-611 pubmed 出版商

Russ A, Louderbough J, Zarnescu D, Schroeder J. Hugl1 and Hugl2 in mammary epithelial cells: polarity, proliferation, and differentiation. PLoS ONE. 2012;7:e47734 pubmed 出版商

Ren Y, Chaerkady R, Hu S, Wan J, Qian J, Zhu H, et al. Unbiased discovery of interactions at a control locus driving expression of the cancer-specific therapeutic and diagnostic target, mesothelin. J Proteome Res. 2012;11:5301-10 pubmed 出版商

Yamamuro T, Hori M, Nakagawa Y, Hayashi T, Sakamoto S, Ohnishi J, et al. Tickling stimulation causes the up-regulation of the kallikrein family in the submandibular gland of the rat. Behav Brain Res. 2013;236:236-43 pubmed 出版商

Stary S, Vinatzer U, Müllauer L, Raderer M, Birner P, Streubel B. t(11;14)(q23;q32) involving IGH and DDX6 in nodal marginal zone lymphoma. Genes Chromosomes Cancer. 2013;52:33-43 pubmed 出版商

Davies K, Le A, Theodoro M, Skokan M, Aisner D, Berge E, et al. Identifying and targeting ROS1 gene fusions in non-small cell lung cancer. Clin Cancer Res. 2012;18:4570-9 pubmed 出版商

Kim Y, Kim E, Seo Y, Yoon T, Lee W, Lee K. Function of the pentose phosphate pathway and its key enzyme, transketolase, in the regulation of the meiotic cell cycle in oocytes. Clin Exp Reprod Med. 2012;39:58-67 pubmed 出版商

Wehenkel M, Ban J, Ho Y, Carmony K, Hong J, Kim K. A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice. Br J Cancer. 2012;107:53-62 pubmed 出版商

Yue H, Tanaka K, Furukawa T, Karnik S, Li W. Thymidine phosphorylase inhibits vascular smooth muscle cell proliferation via upregulation of STAT3. Biochim Biophys Acta. 2012;1823:1316-23 pubmed 出版商

D Angelo D, Palmieri D, Mussnich P, Roche M, Wierinckx A, Raverot G, et al. Altered microRNA expression profile in human pituitary GH adenomas: down-regulation of miRNA targeting HMGA1, HMGA2, and E2F1. J Clin Endocrinol Metab. 2012;97:E1128-38 pubmed 出版商

Chen L, Xu Y, Zhou J, Wu Y, E Q, Zhu Y. TLR3 dsRNA agonist inhibits growth and invasion of HepG2.2.15 HCC cells. Oncol Rep. 2012;28:200-6 pubmed 出版商

Batista T, Alonso Magdalena P, Vieira E, Amaral M, Cederroth C, Nef S, et al. Short-term treatment with bisphenol-A leads to metabolic abnormalities in adult male mice. PLoS ONE. 2012;7:e33814 pubmed 出版商

Teijeiro J, Marini P. The effect of oviductal deleted in malignant brain tumor 1 over porcine sperm is mediated by a signal transduction pathway that involves pro-AKAP4 phosphorylation. Reproduction. 2012;143:773-85 pubmed 出版商

Repici M, Chen X, Morel M, Doulazmi M, Sclip A, Cannaya V, et al. Specific inhibition of the JNK pathway promotes locomotor recovery and neuroprotection after mouse spinal cord injury. Neurobiol Dis. 2012;46:710-21 pubmed 出版商

McGrath M, Ogawa T, De Bold A. Ras dexamethasone-induced protein 1 is a modulator of hormone secretion in the volume overloaded heart. Am J Physiol Heart Circ Physiol. 2012;302:H1826-37 pubmed 出版商

Lee D, Lee H, Hong S, Choi B, Kim H, Han S, et al. Inositol 1,4,5-trisphosphate 3-kinase A is a novel microtubule-associated protein: PKA-dependent phosphoregulation of microtubule binding affinity. J Biol Chem. 2012;287:15981-95 pubmed 出版商

Yee K, Grochola L, Hamilton G, Grawenda A, Bond E, Taubert H, et al. A RASSF1A polymorphism restricts p53/p73 activation and associates with poor survival and accelerated age of onset of soft tissue sarcoma. Cancer Res. 2012;72:2206-17 pubmed 出版商

Lacerda C, Maclea H, Kisiday J, Orton E. Static and cyclic tensile strain induce myxomatous effector proteins and serotonin in canine mitral valves. J Vet Cardiol. 2012;14:223-30 pubmed 出版商

Dastidar S, Bardai F, Ma C, Price V, Rawat V, Verma P, et al. Isoform-specific toxicity of Mecp2 in postmitotic neurons: suppression of neurotoxicity by FoxG1. J Neurosci. 2012;32:2846-55 pubmed 出版商

Dastidar S, Narayanan S, Stifani S, D Mello S. Transducin-like enhancer of Split-1 (TLE1) combines with Forkhead box protein G1 (FoxG1) to promote neuronal survival. J Biol Chem. 2012;287:14749-59 pubmed 出版商

Lacerda C, Kisiday J, Johnson B, Orton E. Local serotonin mediates cyclic strain-induced phenotype transformation, matrix degradation, and glycosaminoglycan synthesis in cultured sheep mitral valves. Am J Physiol Heart Circ Physiol. 2012;302:H1983-90 pubmed 出版商

Yamada H, Yao Y, Wang X, Zhang Y, Huang Y, Dai W, et al. Haploinsufficiency of SGO1 results in deregulated centrosome dynamics, enhanced chromosomal instability and colon tumorigenesis. Cell Cycle. 2012;11:479-88 pubmed 出版商

Doebele R, Pilling A, Aisner D, Kutateladze T, Le A, Weickhardt A, et al. Mechanisms of resistance to crizotinib in patients with ALK gene rearranged non-small cell lung cancer. Clin Cancer Res. 2012;18:1472-82 pubmed 出版商

Wolf A, Beuerlein K, Eckart C, Weiser H, Dickkopf B, Müller H, et al. Identification and functional characterization of novel phosphorylation sites in TAK1-binding protein (TAB) 1. PLoS ONE. 2011;6:e29256 pubmed 出版商

Zhao F, Siu M, Jiang L, Tam K, Ngan H, Le X, et al. Overexpression of dedicator of cytokinesis I (Dock180) in ovarian cancer correlated with aggressive phenotype and poor patient survival. Histopathology. 2011;59:1163-72 pubmed 出版商

Glienke W, Maute L, Wicht J, Bergmann L. The dual PI3K/mTOR inhibitor NVP-BGT226 induces cell cycle arrest and regulates Survivin gene expression in human pancreatic cancer cell lines. Tumour Biol. 2012;33:757-65 pubmed 出版商

Mannava S, Zhuang D, Nair J, Bansal R, Wawrzyniak J, Zucker S, et al. KLF9 is a novel transcriptional regulator of bortezomib- and LBH589-induced apoptosis in multiple myeloma cells. Blood. 2012;119:1450-8 pubmed 出版商

Iovine B, Iannella M, Nocella F, Pricolo M, Bevilacqua M. Carnosine inhibits KRAS-mediated HCT116 proliferation by affecting ATP and ROS production. Cancer Lett. 2012;315:122-8 pubmed 出版商

Freeman M, Kim J, Lisanti M, Di Vizio D. A metabolic perturbation by U0126 identifies a role for glutamine in resveratrol-induced cell death. Cancer Biol Ther. 2011;12:966-77 pubmed 出版商

Maddalena F, Laudiero G, Piscazzi A, Secondo A, Scorziello A, Lombardi V, et al. Sorcin induces a drug-resistant phenotype in human colorectal cancer by modulating Ca(2+) homeostasis. Cancer Res. 2011;71:7659-69 pubmed 出版商

Westmark C, Westmark P, O Riordan K, Ray B, Hervey C, Salamat M, et al. Reversal of fragile X phenotypes by manipulation of A?PP/A? levels in Fmr1KO mice. PLoS ONE. 2011;6:e26549 pubmed 出版商

Léveillé N, Elkon R, Davalos V, Manoharan V, Hollingworth D, Oude Vrielink J, et al. Selective inhibition of microRNA accessibility by RBM38 is required for p53 activity. Nat Commun. 2011;2:513 pubmed 出版商

Kim E, Yoon S, Kim E, Kim Y, Lee H, Kim K, et al. Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation. PLoS ONE. 2011;6:e25870 pubmed 出版商

Lai P, Huang Y, Wu C, Lai C, Wang P, Chiu T. Ceftriaxone attenuates hypoxic-ischemic brain injury in neonatal rats. J Biomed Sci. 2011;18:69 pubmed 出版商

Yun J, Frankenberger C, Kuo W, Boelens M, Eves E, Cheng N, et al. Signalling pathway for RKIP and Let-7 regulates and predicts metastatic breast cancer. EMBO J. 2011;30:4500-14 pubmed 出版商

Rzeczkowski K, Beuerlein K, Müller H, Dittrich Breiholz O, Schneider H, Kettner Buhrow D, et al. c-Jun N-terminal kinase phosphorylates DCP1a to control formation of P bodies. J Cell Biol. 2011;194:581-96 pubmed 出版商

Uhlmann M, Georges R, Boleij A, Eyol E, Kubarenko A, Adwan H, et al. Influence of osteopontin expression on the metastatic growth of CC531 rat colorectal carcinoma cells in rat liver. Cancer Gene Ther. 2011;18:795-805 pubmed 出版商

Kim K, Kim E, Kim Y, Kim E, Lee H, Yoon S, et al. Gas6 downregulation impaired cytoplasmic maturation and pronuclear formation independent to the MPF activity. PLoS ONE. 2011;6:e23304 pubmed 出版商

Pavone L, Cattaneo F, Rea S, De Pasquale V, Spina A, Sauchelli E, et al. Intracellular signaling cascades triggered by the NK1 fragment of hepatocyte growth factor in human prostate epithelial cell line PNT1A. Cell Signal. 2011;23:1961-71 pubmed 出版商

Thompson S, Ashley M, Stohr S, Schindler C, Li M, McCarthy Culpepper K, et al. Suppression of TNF receptor-1 signaling in an in vitro model of epileptic tolerance. Int J Physiol Pathophysiol Pharmacol. 2011;3:120-32 pubmed

Herzog B, Pellet Many C, Britton G, Hartzoulakis B, Zachary I. VEGF binding to NRP1 is essential for VEGF stimulation of endothelial cell migration, complex formation between NRP1 and VEGFR2, and signaling via FAK Tyr407 phosphorylation. Mol Biol Cell. 2011;22:2766-76 pubmed 出版商

Sulis M, Saftig P, Ferrando A. Redundancy and specificity of the metalloprotease system mediating oncogenic NOTCH1 activation in T-ALL. Leukemia. 2011;25:1564-9 pubmed 出版商

Miao J, Choi S, Seok S, Yang L, Zuercher W, Xu Y, et al. Ligand-dependent regulation of the activity of the orphan nuclear receptor, small heterodimer partner (SHP), in the repression of bile acid biosynthetic CYP7A1 and CYP8B1 genes. Mol Endocrinol. 2011;25:1159-69 pubmed 出版商

Meissner J, FREUND R, Krone D, Umeda P, Chang K, Gros G, et al. Extracellular signal-regulated kinase 1/2-mediated phosphorylation of p300 enhances myosin heavy chain I/beta gene expression via acetylation of nuclear factor of activated T cells c1. Nucleic Acids Res. 2011;39:5907-25 pubmed 出版商

Nielsen J, Kristensen D, Almstrup K, Jørgensen A, Olesen I, Jacobsen G, et al. A novel double staining strategy for improved detection of testicular carcinoma in situ cells in human semen samples. Andrologia. 2012;44:78-85 pubmed 出版商

Belakavadi M, Dell J, Grover G, Fondell J. Thyroid hormone suppression of ?-amyloid precursor protein gene expression in the brain involves multiple epigenetic regulatory events. Mol Cell Endocrinol. 2011;339:72-80 pubmed 出版商

Koumakpayi I, Le Page C, Delvoye N, Saad F, Mes Masson A. Macropinocytosis inhibitors and Arf6 regulate ErbB3 nuclear localization in prostate cancer cells. Mol Carcinog. 2011;50:901-12 pubmed 出版商

Shen H, Lusardi T, Williams Karnesky R, Lan J, Poulsen D, Boison D. Adenosine kinase determines the degree of brain injury after ischemic stroke in mice. J Cereb Blood Flow Metab. 2011;31:1648-59 pubmed 出版商

Arduini A, Serviddio G, Escobar J, Tormos A, Bellanti F, Vina J, et al. Mitochondrial biogenesis fails in secondary biliary cirrhosis in rats leading to mitochondrial DNA depletion and deletions. Am J Physiol Gastrointest Liver Physiol. 2011;301:G119-27 pubmed 出版商

Thompson E, Zhu S, Hall J, House J, Ranjan R, Burr J, et al. C/EBP? expression is downregulated in human nonmelanoma skin cancers and inactivation of C/EBP? confers susceptibility to UVB-induced skin squamous cell carcinomas. J Invest Dermatol. 2011;131:1339-46 pubmed 出版商

Watkins M, Grimston S, Norris J, Guillotin B, Shaw A, Beniash E, et al. Osteoblast connexin43 modulates skeletal architecture by regulating both arms of bone remodeling. Mol Biol Cell. 2011;22:1240-51 pubmed 出版商

Ren Y, Patel K, Paun B, Kern S. Structural analysis of the cancer-specific promoter in mesothelin and in other genes overexpressed in cancers. J Biol Chem. 2011;286:11960-9 pubmed 出版商

Shields M, Dangi Garimella S, Krantz S, Bentrem D, Munshi H. Pancreatic cancer cells respond to type I collagen by inducing snail expression to promote membrane type 1 matrix metalloproteinase-dependent collagen invasion. J Biol Chem. 2011;286:10495-504 pubmed 出版商

Dastidar S, Landrieu P, D Mello S. FoxG1 promotes the survival of postmitotic neurons. J Neurosci. 2011;31:402-13 pubmed 出版商

Glienke W, Hausmann E, Bergmann L. Downregulation of STAT3 signaling induces apoptosis but also promotes anti-apoptotic gene expression in human pancreatic cancer cell lines. Tumour Biol. 2011;32:493-500 pubmed 出版商

Al Sabbagh M, Fusi L, Higham J, Lee Y, Lei K, Hanyaloglu A, et al. NADPH oxidase-derived reactive oxygen species mediate decidualization of human endometrial stromal cells in response to cyclic AMP signaling. Endocrinology. 2011;152:730-40 pubmed 出版商

Wang X, Bjorklund S, Wasik A, Grandien A, Andersson P, Kimby E, et al. Gene expression profiling and chromatin immunoprecipitation identify DBN1, SETMAR and HIG2 as direct targets of SOX11 in mantle cell lymphoma. PLoS ONE. 2010;5:e14085 pubmed 出版商

Cattaneo F, Guerra G, Ammendola R. Expression and signaling of formyl-peptide receptors in the brain. Neurochem Res. 2010;35:2018-26 pubmed 出版商

Cervenka I, Wolf J, Masek J, Krejci P, Wilcox W, Kozubik A, et al. Mitogen-activated protein kinases promote WNT/beta-catenin signaling via phosphorylation of LRP6. Mol Cell Biol. 2011;31:179-89 pubmed 出版商

Bravard A, Lefai E, Meugnier E, Pesenti S, Disse E, Vouillarmet J, et al. FTO is increased in muscle during type 2 diabetes, and its overexpression in myotubes alters insulin signaling, enhances lipogenesis and ROS production, and induces mitochondrial dysfunction. Diabetes. 2011;60:258-68 pubmed 出版商

Palchykova S, Winsky Sommerer R, Shen H, Boison D, Gerling A, Tobler I. Manipulation of adenosine kinase affects sleep regulation in mice. J Neurosci. 2010;30:13157-65 pubmed 出版商

Kuo W, Liu J, Mauceri H, Vokes E, Weichselbaum R, Rosner M, et al. Efficacy of the multi-kinase inhibitor enzastaurin is dependent on cellular signaling context. Mol Cancer Ther. 2010;9:2814-24 pubmed 出版商

Butler T, Esposito G, Blue G, Cole A, Costa M, Waddell L, et al. GATA4 mutations in 357 unrelated patients with congenital heart malformation. Genet Test Mol Biomarkers. 2010;14:797-802 pubmed 出版商

Sperandio S, Poksay K, Schilling B, Crippen D, Gibson B, Bredesen D. Identification of new modulators and protein alterations in non-apoptotic programmed cell death. J Cell Biochem. 2010;111:1401-12 pubmed 出版商

LaLone C, Huang N, Rizshsky L, Yum M, Singh N, Hauck C, et al. Enrichment of Echinacea angustifolia with Bauer alkylamide 11 and Bauer ketone 23 increased anti-inflammatory potential through interference with cox-2 enzyme activity. J Agric Food Chem. 2010;58:8573-84 pubmed 出版商

Landriscina M, Laudiero G, Maddalena F, Amoroso M, Piscazzi A, Cozzolino F, et al. Mitochondrial chaperone Trap1 and the calcium binding protein Sorcin interact and protect cells against apoptosis induced by antiblastic agents. Cancer Res. 2010;70:6577-86 pubmed 出版商

Zhao H, Kim G, Liu C, Levine R. Transgenic mice overexpressing methionine sulfoxide reductase A: characterization of embryonic fibroblasts. Free Radic Biol Med. 2010;49:641-8 pubmed 出版商

Li P, Jayarama S, Ganesh L, Mordi D, Carr R, Kanteti P, et al. Akt-phosphorylated mitogen-activated kinase-activating death domain protein (MADD) inhibits TRAIL-induced apoptosis by blocking Fas-associated death domain (FADD) association with death receptor 4. J Biol Chem. 2010;285:22713-22 pubmed 出版商

DU H, Sarno J, Taylor H. HOXA10 inhibits Kruppel-like factor 9 expression in the human endometrial epithelium. Biol Reprod. 2010;83:205-11 pubmed 出版商

Redon S, Reichenbach P, Lingner J. The non-coding RNA TERRA is a natural ligand and direct inhibitor of human telomerase. Nucleic Acids Res. 2010;38:5797-806 pubmed 出版商

Blomberg Jensen M, Andersen C, Nielsen J, Bagi P, Jørgensen A, Juul A, et al. Expression of the vitamin D receptor, 25-hydroxylases, 1alpha-hydroxylase and 24-hydroxylase in the human kidney and renal clear cell cancer. J Steroid Biochem Mol Biol. 2010;121:376-82 pubmed 出版商

Masuda M, Maruyama T, Ohta T, Ito A, Hayashi T, Tsukasaki K, et al. CADM1 interacts with Tiam1 and promotes invasive phenotype of human T-cell leukemia virus type I-transformed cells and adult T-cell leukemia cells. J Biol Chem. 2010;285:15511-22 pubmed 出版商

Gridling M, Popescu R, Kopp B, Wagner K, Krenn L, Krupitza G. Anti-leukaemic effects of two extract types of Lactuca sativa correlate with the activation of Chk2, induction of p21, downregulation of cyclin D1 and acetylation of alpha-tubulin. Oncol Rep. 2010;23:1145-51 pubmed

Lee H, Kim E, Kim K, Moon J, Park K, Kim K, et al. Obox4 critically regulates cAMP-dependent meiotic arrest and MI-MII transition in oocytes. FASEB J. 2010;24:2314-24 pubmed 出版商

Zhang P, Wang H, Rowe P, Hu B, Wang Y. MEPE/OF45 as a new target for sensitizing human tumour cells to DNA damage inducers. Br J Cancer. 2010;102:862-6 pubmed 出版商

Wang L, Ankati H, Akubathini S, Balderamos M, Storey C, Patel A, et al. Identification of novel 1,4-benzoxazine compounds that are protective in tissue culture and in vivo models of neurodegeneration. J Neurosci Res. 2010;88:1970-84 pubmed 出版商

Young J, Patel A, Rai P. Suppression of thioredoxin-1 induces premature senescence in normal human fibroblasts. Biochem Biophys Res Commun. 2010;392:363-8 pubmed 出版商

Kapeta S, Chondrogianni N, Gonos E. Nuclear erythroid factor 2-mediated proteasome activation delays senescence in human fibroblasts. J Biol Chem. 2010;285:8171-84 pubmed 出版商

Yen A, Yang J. Cdc20 proteolysis requires p38 MAPK signaling and Cdh1-independent APC/C ubiquitination during spindle assembly checkpoint activation by cadmium. J Cell Physiol. 2010;223:327-34 pubmed 出版商

Richards J, Waterworth D, O Rahilly S, Hivert M, Loos R, Perry J, et al. A genome-wide association study reveals variants in ARL15 that influence adiponectin levels. PLoS Genet. 2009;5:e1000768 pubmed 出版商

Huang N, Hauck C, Yum M, Rizshsky L, Widrlechner M, McCoy J, et al. Rosmarinic acid in Prunella vulgaris ethanol extract inhibits lipopolysaccharide-induced prostaglandin E2 and nitric oxide in RAW 264.7 mouse macrophages. J Agric Food Chem. 2009;57:10579-89 pubmed 出版商

Lazar I, Yaacov B, Shiloach T, Eliahoo E, Kadouri L, Lotem M, et al. The oncolytic activity of Newcastle disease virus NDV-HUJ on chemoresistant primary melanoma cells is dependent on the proapoptotic activity of the inhibitor of apoptosis protein Livin. J Virol. 2010;84:639-46 pubmed 出版商

Liu S, Wang H, Wang X, Lu L, Gao N, Rowe P, et al. MEPE/OF45 protects cells from DNA damage induced killing via stabilizing CHK1. Nucleic Acids Res. 2009;37:7447-54 pubmed 出版商

Rafacho A, Giozzet V, Boschero A, Abrantes J, Cestari T, Carneiro E, et al. Reduced pancreatic beta-cell mass is associated with decreased FoxO1 and Erk1/2 protein phosphorylation in low-protein malnourished rats. Braz J Med Biol Res. 2009;42:935-41 pubmed

DU H, Vitiello D, Sarno J, Taylor H. 3-Phosphoglycerate dehydrogenase expression is regulated by HOXA10 in murine endometrium and human endometrial cells. Reproduction. 2010;139:237-45 pubmed 出版商

Stark N, Gridling M, Madlener S, Bauer S, Lackner A, Popescu R, et al. A polar extract of the Maya healing plant Anthurium schlechtendalii (Aracea) exhibits strong in vitro anticancer activity. Int J Mol Med. 2009;24:513-21 pubmed

Ozmen A, Bauer S, Gridling M, Singhuber J, Krasteva S, Madlener S, et al. In vitro anti-neoplastic activity of the ethno-pharmaceutical plant Hypericum adenotrichum Spach endemic to Western Turkey. Oncol Rep. 2009;22:845-52 pubmed

Liu L, Yang C, Herzog C, Seth R, Kaushal G. Proteasome inhibitors prevent cisplatin-induced mitochondrial release of apoptosis-inducing factor and markedly ameliorate cisplatin nephrotoxicity. Biochem Pharmacol. 2010;79:137-46 pubmed 出版商

Ranjan R, Thompson E, Yoon K, Smart R. C/EBPalpha expression is partially regulated by C/EBPbeta in response to DNA damage and C/EBPalpha-deficient fibroblasts display an impaired G1 checkpoint. Oncogene. 2009;28:3235-45 pubmed 出版商

Ozmen A, Madlener S, Bauer S, Krasteva S, Vonach C, Giessrigl B, et al. In vitro anti-leukemic activity of the ethno-pharmacological plant Scutellaria orientalis ssp. carica endemic to western Turkey. Phytomedicine. 2010;17:55-62 pubmed 出版商

Kikuchi K, Fukuda M, Ito T, Inoue M, Yokoi T, Chiku S, et al. Transcripts of unknown function in multiple-signaling pathways involved in human stem cell differentiation. Nucleic Acids Res. 2009;37:4987-5000 pubmed 出版商

Buch C, Lindberg R, Figueroa R, Gudise S, Onischenko E, Hallberg E. An integral protein of the inner nuclear membrane localizes to the mitotic spindle in mammalian cells. J Cell Sci. 2009;122:2100-7 pubmed 出版商

Chen L, Huang W, Lee L, Wang C. Ellagitannins from Terminalia calamansanai induced apoptosis in HL-60 cells. Toxicol In Vitro. 2009;23:603-9 pubmed 出版商

Sun T, Zhao N, Ni C, Zhao X, Zhang W, Su X, et al. Doxycycline inhibits the adhesion and migration of melanoma cells by inhibiting the expression and phosphorylation of focal adhesion kinase (FAK). Cancer Lett. 2009;285:141-50 pubmed 出版商

Yoon S, Kim E, Kim Y, Lee H, Kim K, Bae J, et al. Role of Bcl2-like 10 (Bcl2l10) in Regulating Mouse Oocyte Maturation. Biol Reprod. 2009;81:497-506 pubmed 出版商

Wang F, Wang Y, Yu X, Yang D, Wang Z, Lu C, et al. Significance of Jab1 expression in human esophageal squamous cell carcinoma. J Clin Gastroenterol. 2009;43:520-6 pubmed 出版商

Gridling M, Stark N, Madlener S, Lackner A, Popescu R, Benedek B, et al. In vitro anti-cancer activity of two ethno-pharmacological healing plants from Guatemala Pluchea odorata and Phlebodium decumanum. Int J Oncol. 2009;34:1117-28 pubmed

Fedele M, Palmieri D, Chiappetta G, Pasquinelli R, De Martino I, Arra C, et al. Impairment of the p27kip1 function enhances thyroid carcinogenesis in TRK-T1 transgenic mice. Endocr Relat Cancer. 2009;16:483-90 pubmed 出版商

Khawam K, Giron Michel J, Gu Y, Perier A, Giuliani M, Caignard A, et al. Human renal cancer cells express a novel membrane-bound interleukin-15 that induces, in response to the soluble interleukin-15 receptor alpha chain, epithelial-to-mesenchymal transition. Cancer Res. 2009;69:1561-9 pubmed 出版商

Colombo A, Bastone A, Ploia C, Sclip A, Salmona M, Forloni G, et al. JNK regulates APP cleavage and degradation in a model of Alzheimer's disease. Neurobiol Dis. 2009;33:518-25 pubmed 出版商

Chou T, Chen W, Lee A, Hung S, Shih N, Chen M. Clusterin silencing in human lung adenocarcinoma cells induces a mesenchymal-to-epithelial transition through modulating the ERK/Slug pathway. Cell Signal. 2009;21:704-11 pubmed 出版商

Dangi Garimella S, Yun J, Eves E, Newman M, Erkeland S, Hammond S, et al. Raf kinase inhibitory protein suppresses a metastasis signalling cascade involving LIN28 and let-7. EMBO J. 2009;28:347-58 pubmed 出版商

Wang Y, Wang Y, Cheng C, Ji Y, Zhao Y, Zou L, et al. Expression of Jun activation domain-binding protein 1 and Ser10 phosphorylated p27 protein in human epithelial ovarian carcinoma. J Cancer Res Clin Oncol. 2009;135:951-9 pubmed 出版商

Liu R, Strom A, Zhai J, Gal J, Bao S, Gong W, et al. Enzymatically inactive adenylate kinase 4 interacts with mitochondrial ADP/ATP translocase. Int J Biochem Cell Biol. 2009;41:1371-80 pubmed 出版商

Ginet V, Puyal J, Magnin G, Clarke P, Truttmann A. Limited role of the c-Jun N-terminal kinase pathway in a neonatal rat model of cerebral hypoxia-ischemia. J Neurochem. 2009;108:552-62 pubmed 出版商

Hamada S, Satoh K, Hirota M, Fujibuchi W, Kanno A, Umino J, et al. Expression of the calcium-binding protein S100P is regulated by bone morphogenetic protein in pancreatic duct epithelial cell lines. Cancer Sci. 2009;100:103-10 pubmed 出版商

Diallo J, Betton B, Parent N, Péant B, Lessard L, Le Page C, et al. Enhanced killing of androgen-independent prostate cancer cells using inositol hexakisphosphate in combination with proteasome inhibitors. Br J Cancer. 2008;99:1613-22 pubmed 出版商

Sun W, Zhou L, Hazim R, Quinones Jenab V, Jenab S. Effects of dopamine and NMDA receptors on cocaine-induced Fos expression in the striatum of Fischer rats. Brain Res. 2008;1243:1-9 pubmed 出版商

Kim K, Kim E, Lee K. SEBOX is essential for early embryogenesis at the two-cell stage in the mouse. Biol Reprod. 2008;79:1192-201 pubmed 出版商

Shukla S, Gupta S. Apigenin suppresses insulin-like growth factor I receptor signaling in human prostate cancer: an in vitro and in vivo study. Mol Carcinog. 2009;48:243-252 pubmed 出版商

Kaur P, Shukla S, Gupta S. Plant flavonoid apigenin inactivates Akt to trigger apoptosis in human prostate cancer: an in vitro and in vivo study. Carcinogenesis. 2008;29:2210-7 pubmed 出版商

Sundaresan N, Samant S, Pillai V, Rajamohan S, Gupta M. SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70. Mol Cell Biol. 2008;28:6384-401 pubmed 出版商

Kato T, Shimano H, Yamamoto T, Ishikawa M, Kumadaki S, Matsuzaka T, et al. Palmitate impairs and eicosapentaenoate restores insulin secretion through regulation of SREBP-1c in pancreatic islets. Diabetes. 2008;57:2382-92 pubmed 出版商

Day R, Barshishat Kupper M, Mog S, McCart E, Prasanna P, Davis T, et al. Genistein protects against biomarkers of delayed lung sequelae in mice surviving high-dose total body irradiation. J Radiat Res. 2008;49:361-72 pubmed

Sulis M, Williams O, Palomero T, Tosello V, Pallikuppam S, Real P, et al. NOTCH1 extracellular juxtamembrane expansion mutations in T-ALL. Blood. 2008;112:733-40 pubmed 出版商

Wang Y, Fei M, Cheng C, Zhang D, Lu J, He S, et al. Jun activation domain-binding protein 1 negatively regulate p27 kip1 in non-Hodgkin's lymphomas. Cancer Biol Ther. 2008;7:460-7 pubmed

Buerki C, Rothgiesser K, Valovka T, Owen H, Rehrauer H, Fey M, et al. Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65. Nucleic Acids Res. 2008;36:1665-80 pubmed 出版商

Yang C, Kaushal V, Shah S, Kaushal G. Autophagy is associated with apoptosis in cisplatin injury to renal tubular epithelial cells. Am J Physiol Renal Physiol. 2008;294:F777-87 pubmed 出版商

Yuan H, Zhang P, Qin L, Chen L, Shi S, Lu Y, et al. Overexpression of SPINDLIN1 induces cellular senescence, multinucleation and apoptosis. Gene. 2008;410:67-74 pubmed 出版商

Dudakovic A, Wiemer A, Lamb K, Vonnahme L, Dietz S, Hohl R. Inhibition of geranylgeranyl diphosphate synthase induces apoptosis through multiple mechanisms and displays synergy with inhibition of other isoprenoid biosynthetic enzymes. J Pharmacol Exp Ther. 2008;324:1028-36 pubmed

Yang C, Kaushal V, Haun R, Seth R, Shah S, Kaushal G. Transcriptional activation of caspase-6 and -7 genes by cisplatin-induced p53 and its functional significance in cisplatin nephrotoxicity. Cell Death Differ. 2008;15:530-44 pubmed

Bruno T, Iezzi S, De Nicola F, Di Padova M, DeSantis A, Scarsella M, et al. Che-1 activates XIAP expression in response to DNA damage. Cell Death Differ. 2008;15:515-20 pubmed

Li Y, Qin Y, Li H, Wu R, Yan C, Du H. Lysosomal acid lipase over-expression disrupts lamellar body genesis and alveolar structure in the lung. Int J Exp Pathol. 2007;88:427-36 pubmed

Van Der Velden J, Schols A, Willems J, Kelders M, Langen R. Glycogen synthase kinase 3 suppresses myogenic differentiation through negative regulation of NFATc3. J Biol Chem. 2008;283:358-66 pubmed

Anhê G, Nogueira T, Nicoletti Carvalho J, Lellis Santos C, Barbosa H, Cipolla Neto J, et al. Signal transducer and activator of transcription 3-regulated sarcoendoplasmic reticulum Ca2+-ATPase 2 expression by prolactin and glucocorticoids is involved in the adaptation of insulin secretory response during the peripartum period. J Endocrinol. 2007;195:17-27 pubmed

Wang X, Southard R, Allred C, TALBERT D, Wilson M, Kilgore M. MAZ drives tumor-specific expression of PPAR gamma 1 in breast cancer cells. Breast Cancer Res Treat. 2008;111:103-11 pubmed

Repici M, Centeno C, Tomasi S, Forloni G, Bonny C, Vercelli A, et al. Time-course of c-Jun N-terminal kinase activation after cerebral ischemia and effect of D-JNKI1 on c-Jun and caspase-3 activation. Neuroscience. 2007;150:40-9 pubmed

Berger N, Ben Bassat H, Klein B, Laskov R. Cytotoxicity of NF-kappaB inhibitors Bay 11-7085 and caffeic acid phenethyl ester to Ramos and other human B-lymphoma cell lines. Exp Hematol. 2007;35:1495-509 pubmed

Deng M, Mohanan S, Polyak E, Chacko S. Caldesmon is necessary for maintaining the actin and intermediate filaments in cultured bladder smooth muscle cells. Cell Motil Cytoskeleton. 2007;64:951-65 pubmed

Lu X, Yi H, Xu J, Sun Y, Li J, Cao S, et al. A novel synthetic oleanolic acid derivative with amino acid conjugate suppresses tumour growth by inducing cell cycle arrest. J Pharm Pharmacol. 2007;59:1087-93 pubmed

Borsello T, Centeno C, Riederer I, Haefliger J, Riederer B. Phosphorylation-dependent dimerization and subcellular localization of islet-brain 1/c-Jun N-terminal kinase-interacting protein 1. J Neurosci Res. 2007;85:3632-41 pubmed

Sanz González S, Barquín L, Garcia Cao I, Roque M, Gonzalez J, Fuster J, et al. Increased p53 gene dosage reduces neointimal thickening induced by mechanical injury but has no effect on native atherosclerosis. Cardiovasc Res. 2007;75:803-12 pubmed

De Nicola F, Bruno T, Iezzi S, Di Padova M, Floridi A, Passananti C, et al. The prolyl isomerase Pin1 affects Che-1 stability in response to apoptotic DNA damage. J Biol Chem. 2007;282:19685-91 pubmed

Bellavia D, Mecarozzi M, Campese A, Grazioli P, Talora C, Frati L, et al. Notch3 and the Notch3-upregulated RNA-binding protein HuD regulate Ikaros alternative splicing. EMBO J. 2007;26:1670-80 pubmed

Niimi H, Pardali K, Vanlandewijck M, Heldin C, Moustakas A. Notch signaling is necessary for epithelial growth arrest by TGF-beta. J Cell Biol. 2007;176:695-707 pubmed

Koch H, Zhang R, Verdoodt B, Bailey A, Zhang C, Yates J, et al. Large-scale identification of c-MYC-associated proteins using a combined TAP/MudPIT approach. Cell Cycle. 2007;6:205-17 pubmed

Lin L, Czapiga M, Nini L, Zhang J, Simonds W. Nuclear localization of the parafibromin tumor suppressor protein implicated in the hyperparathyroidism-jaw tumor syndrome enhances its proapoptotic function. Mol Cancer Res. 2007;5:183-93 pubmed

Lessard L, Saad F, Le Page C, Diallo J, Péant B, Delvoye N, et al. NF-kappaB2 processing and p52 nuclear accumulation after androgenic stimulation of LNCaP prostate cancer cells. Cell Signal. 2007;19:1093-100 pubmed

Glienke W, Chow K, Bauer N, Bergmann L. Down-regulation of wt1 expression in leukemia cell lines as part of apoptotic effect in arsenic treatment using two compounds. Leuk Lymphoma. 2006;47:1629-38 pubmed

Linggi B, Carpenter G. ErbB-4 s80 intracellular domain abrogates ETO2-dependent transcriptional repression. J Biol Chem. 2006;281:25373-80 pubmed

Huan S, Lee H, Liu D, Wu C, Wang C. Cantharidin-induced cytotoxicity and cyclooxygenase 2 expression in human bladder carcinoma cell line. Toxicology. 2006;223:136-43 pubmed

Anhê G, Torrão A, Nogueira T, Caperuto L, Amaral M, Medina M, et al. ERK3 associates with MAP2 and is involved in glucose-induced insulin secretion. Mol Cell Endocrinol. 2006;251:33-41 pubmed

Laskov R, Berger N, Horwitz M. Differential effects of tumor necrosis factor-alpha and CD40L on NF-kappa B inhibitory proteins I kappa B alpha, beta and epsilon and on the induction of the Jun amino-terminal kinase pathway in Ramos Burkitt lymphoma cells. Eur Cytokine Netw. 2005;16:267-76 pubmed

Hamada S, Satoh K, Kimura K, Kanno A, Masamune A, Shimosegawa T. MSX2 overexpression inhibits gemcitabine-induced caspase-3 activity in pancreatic cancer cells. World J Gastroenterol. 2005;11:6867-70 pubmed

Chao S, Wu A, Lee C, Chen F, Wang C. Anti-inflammatory effects of indomethacin's methyl ester derivative and induction of apoptosis in HL-60 Cells. Biol Pharm Bull. 2005;28:2206-10 pubmed

Kuba T, Wu H, Nazarian A, Festa E, Barr G, Jenab S, et al. Estradiol and progesterone differentially regulate formalin-induced nociception in ovariectomized female rats. Horm Behav. 2006;49:441-9 pubmed

Sanz González S, Melero Fernández de Mera R, Malek N, Andres V. Atheroma development in apolipoprotein E-null mice is not regulated by phosphorylation of p27(Kip1) on threonine 187. J Cell Biochem. 2006;97:735-43 pubmed

Wersinger C, Sidhu A. Disruption of the interaction of alpha-synuclein with microtubules enhances cell surface recruitment of the dopamine transporter. Biochemistry. 2005;44:13612-24 pubmed

Tacke F, Liedtke C, Bocklage S, Manns M, Trautwein C. CREB/PKA sensitive signalling pathways activate and maintain expression levels of the hepatitis B virus pre-S2/S promoter. Gut. 2005;54:1309-17 pubmed

Febbo P, Lowenberg M, Thorner A, Brown M, Loda M, Golub T. Androgen mediated regulation and functional implications of fkbp51 expression in prostate cancer. J Urol. 2005;173:1772-7 pubmed

Luedde T, Assmus U, Wüstefeld T, Meyer zu Vilsendorf A, Roskams T, Schmidt Supprian M, et al. Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury. J Clin Invest. 2005;115:849-59 pubmed

Franchimont N, Lambert C, Huynen P, Ribbens C, Relic B, Chariot A, et al. Interleukin-6 receptor shedding is enhanced by interleukin-1beta and tumor necrosis factor alpha and is partially mediated by tumor necrosis factor alpha-converting enzyme in osteoblast-like cells. Arthritis Rheum. 2005;52:84-93 pubmed

Covic M, Hassa P, Saccani S, Buerki C, Meier N, Lombardi C, et al. Arginine methyltransferase CARM1 is a promoter-specific regulator of NF-kappaB-dependent gene expression. EMBO J. 2005;24:85-96 pubmed

Wong C, Xia W, Lee N, Mruk D, Lee W, Cheng C. Regulation of ectoplasmic specialization dynamics in the seminiferous epithelium by focal adhesion-associated proteins in testosterone-suppressed rat testes. Endocrinology. 2005;146:1192-204 pubmed

Woodard G, Lin L, Zhang J, Agarwal S, Marx S, Simonds W. Parafibromin, product of the hyperparathyroidism-jaw tumor syndrome gene HRPT2, regulates cyclin D1/PRAD1 expression. Oncogene. 2005;24:1272-6 pubmed