产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
Akt1/2/3(H-136)
目录 :
sc-8312
共轭标签 :
未共轭
反应物种 :
人类, 小鼠, 大鼠, 斑马鱼
应用 :
免疫印迹
更多信息或购买 :
文章摘录数: 49
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 3h
Rigiracciolo D, Nohata N, Lappano R, Cirillo F, Talia M, Scordamaglia D, et al. IGF-1/IGF-1R/FAK/YAP Transduction Signaling Prompts Growth Effects in Triple-Negative Breast Cancer (TNBC) Cells. Cells. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 图 5c
Lin C, Lin W, Cho R, Yang C, Yeh Y, Hsiao L, et al. Induction of HO-1 by Mevastatin Mediated via a Nox/ROS-Dependent c-Src/PDGFRα/PI3K/Akt/Nrf2/ARE Cascade Suppresses TNF-α-Induced Lung Inflammation. J Clin Med. 2020;9: pubmed 出版商
  • 免疫印迹; 人类; 图 2
Xiao Z, Gaertner S, Morresi Hauf A, Genzel R, Duell T, Ullrich A, et al. Metformin Triggers Autophagy to Attenuate Drug-Induced Apoptosis in NSCLC Cells, with Minor Effects on Tumors of Diabetic Patients. Neoplasia. 2017;19:385-395 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 5a
Chang H, Chang Y, Lai S, Chen K, Wang K, Chiu T, et al. Naringenin inhibits migration of lung cancer cells via the inhibition of matrix metalloproteinases-2 and -9. Exp Ther Med. 2017;13:739-744 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Yang K, Chen Y, To K, Wang F, Li D, Chen L, et al. Alectinib (CH5424802) antagonizes ABCB1- and ABCG2-mediated multidrug resistance in vitro, in vivo and ex vivo. Exp Mol Med. 2017;49:e303 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 13b
Koyama Y, Wang P, Liang S, Iwaisako K, Liu X, Xu J, et al. Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. J Clin Invest. 2017;127:1254-1270 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Banerjee Mustafi S, Chakraborty P, Dwivedi S, Ding K, Moxley K, Mukherjee P, et al. BMI1, a new target of CK2?. Mol Cancer. 2017;16:56 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Kim H, Lee S, Kim C, Kim Y, Ju W, Kim S. Subcellular localization of FOXO3a as a potential biomarker of response to combined treatment with inhibitors of PI3K and autophagy in PIK3CA-mutant cancer cells. Oncotarget. 2017;8:6608-6622 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4a
Dragoj M, Milosević Z, Bankovic J, Tanic N, Pesic M, Stankovic T. Targeting CXCR4 and FAK reverses doxorubicin resistance and suppresses invasion in non-small cell lung carcinoma. Cell Oncol (Dordr). 2017;40:47-62 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 6a
Visuttijai K, Pettersson J, Mehrbani Azar Y, van den Bout I, Orndal C, Marcickiewicz J, et al. Lowered Expression of Tumor Suppressor Candidate MYO1C Stimulates Cell Proliferation, Suppresses Cell Adhesion and Activates AKT. PLoS ONE. 2016;11:e0164063 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 8a
Olianas M, Dedoni S, Onali P. LPA1 Mediates Antidepressant-Induced ERK1/2 Signaling and Protection from Oxidative Stress in Glial Cells. J Pharmacol Exp Ther. 2016;359:340-353 pubmed
  • 免疫印迹; 人类; 1:1000; 图 5a
Zeng Y, Yao X, Chen L, Yan Z, Liu J, Zhang Y, et al. Sphingosine-1-phosphate induced epithelial-mesenchymal transition of hepatocellular carcinoma via an MMP-7/ syndecan-1/TGF-β autocrine loop. Oncotarget. 2016;7:63324-63337 pubmed 出版商
  • 免疫印迹; 人类; 图 2b
Singh A, Fedele C, Lu H, Nevalainen M, Keen J, Languino L. Exosome-mediated Transfer of αvβ3 Integrin from Tumorigenic to Nontumorigenic Cells Promotes a Migratory Phenotype. Mol Cancer Res. 2016;14:1136-1146 pubmed
  • 免疫印迹; 人类; 1:2000; 图 5d
Tisza M, Zhao W, Fuentes J, Prijic S, Chen X, Levental I, et al. Motility and stem cell properties induced by the epithelial-mesenchymal transition require destabilization of lipid rafts. Oncotarget. 2016;7:51553-51568 pubmed 出版商
  • 免疫印迹; 人类; 图 7
Rorsman C, Tsioumpekou M, Heldin C, Lennartsson J. The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling. J Biol Chem. 2016;291:11608-18 pubmed 出版商
  • 免疫印迹; 斑马鱼; 1:1000; 图 2
Hirth S, Bühler A, Bührdel J, Rudeck S, Dahme T, Rottbauer W, et al. Paxillin and Focal Adhesion Kinase (FAK) Regulate Cardiac Contractility in the Zebrafish Heart. PLoS ONE. 2016;11:e0150323 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Chen C, Lee T, Kwok C, Hsu Y, Shih K, Lin Y, et al. Cannabinoid receptor type 1 mediates high-fat diet-induced insulin resistance by increasing forkhead box O1 activity in a mouse model of obesity. Int J Mol Med. 2016;37:743-54 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7d
Chen Y, Zheng Y, You X, Yu M, Fu G, Su X, et al. Kras Is Critical for B Cell Lymphopoiesis. J Immunol. 2016;196:1678-85 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500
Romano López A, Méndez Díaz M, García F, Regalado Santiago C, Ruiz Contreras A, Prospero Garcia O. Maternal separation and early stress cause long-lasting effects on dopaminergic and endocannabinergic systems and alters dendritic morphology in the nucleus accumbens and frontal cortex in rats. Dev Neurobiol. 2016;76:819-31 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Gustavo Vazquez Jimenez J, Chavez Reyes J, Romero Garcia T, Zarain Herzberg A, Valdes Flores J, Manuel Galindo Rosales J, et al. Palmitic acid but not palmitoleic acid induces insulin resistance in a human endothelial cell line by decreasing SERCA pump expression. Cell Signal. 2016;28:53-9 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Mehner C, Oberg A, Kalli K, Nassar A, Hockla A, Pendlebury D, et al. Serine protease inhibitor Kazal type 1 (SPINK1) drives proliferation and anoikis resistance in a subset of ovarian cancers. Oncotarget. 2015;6:35737-54 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 1c
  • 免疫印迹; 小鼠; 1:2000; 图 1b
Lee M, Jeong M, Lee H, Han H, Ko A, Hewitt S, et al. PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis. Nat Commun. 2015;6:7769 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
Arruda A, Pers B, Parlakgül G, Güney E, Inouye K, Hotamisligil G. Chronic enrichment of hepatic endoplasmic reticulum-mitochondria contact leads to mitochondrial dysfunction in obesity. Nat Med. 2014;20:1427-35 pubmed 出版商
Garcia Puga M, Sáenz Antoñanzas A, Fernandez Torron R, Munain A, Matheu A. Myotonic Dystrophy type 1 cells display impaired metabolism and mitochondrial dysfunction that are reversed by metformin. Aging (Albany NY). 2020;12:6260-6275 pubmed 出版商
Nam K, Yi S, Nam G, Noh J, Park J, Lee M, et al. Identification of a novel S6K1 inhibitor, rosmarinic acid methyl ester, for treating cisplatin-resistant cervical cancer. BMC Cancer. 2019;19:773 pubmed 出版商
Schreiber C, Saraswati S, Harkins S, Gruber A, Cremers N, Thiele W, et al. Loss of ASAP1 in mice impairs adipogenic and osteogenic differentiation of mesenchymal progenitor cells through dysregulation of FAK/Src and AKT signaling. PLoS Genet. 2019;15:e1008216 pubmed 出版商
Sivaram N, McLaughlin P, Han H, Petrenko O, Jiang Y, Ballou L, et al. Tumor-intrinsic PIK3CA represses tumor immunogenecity in a model of pancreatic cancer. J Clin Invest. 2019;130: pubmed 出版商
Hwang J, Kim A, Kim K, Il Park J, Oh H, Moon S, et al. TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression. Nat Commun. 2019;10:421 pubmed 出版商
Fenizia C, Bottino C, Corbetta S, Fittipaldi R, Floris P, Gaudenzi G, et al. SMYD3 promotes the epithelial-mesenchymal transition in breast cancer. Nucleic Acids Res. 2019;47:1278-1293 pubmed 出版商
Baek H, Kim S, Choi E, Kim J, Shin D, Park E, et al. Inhibition of Estrogen Signaling Reduces the Incidence of BRCA1-associated Mammary Tumor Formation. Int J Biol Sci. 2018;14:1755-1768 pubmed 出版商
Dai B, Li H, Fan J, Zhao Y, Yin Z, Nie X, et al. MiR-21 protected against diabetic cardiomyopathy induced diastolic dysfunction by targeting gelsolin. Cardiovasc Diabetol. 2018;17:123 pubmed 出版商
García Gil A, Galán Enríquez C, Perez Lopez A, Nava P, Alpuche Aranda C, Ortiz Navarrete V. SopB activates the Akt-YAP pathway to promote Salmonella survival within B cells. Virulence. 2018;9:1390-1402 pubmed 出版商
Cho R, Yang C, Tseng H, Hsiao L, Lin C, Yang C. Haem oxygenase-1 up-regulation by rosiglitazone via ROS-dependent Nrf2-antioxidant response elements axis or PPARγ attenuates LPS-mediated lung inflammation. Br J Pharmacol. 2018;175:3928-3946 pubmed 出版商
Li X, Zhong L, Wang Z, Chen H, Liao D, Zhang R, et al. Phosphorylation of IRS4 by CK1γ2 promotes its degradation by CHIP through the ubiquitin/lysosome pathway. Theranostics. 2018;8:3643-3653 pubmed 出版商
Cho J, You Y, Yeom Y, Lee D, Kim B, Won M, et al. RNF25 promotes gefitinib resistance in EGFR-mutant NSCLC cells by inducing NF-?B-mediated ERK reactivation. Cell Death Dis. 2018;9:587 pubmed 出版商
Yu Y, Du H, Wei S, Feng L, Li J, Yao F, et al. Adipocyte-Derived Exosomal MiR-27a Induces Insulin Resistance in Skeletal Muscle Through Repression of PPARγ. Theranostics. 2018;8:2171-2188 pubmed 出版商
Wang B, Luo Y, Zhou X, Li R. Trifluoperazine induces apoptosis through the upregulation of Bax/Bcl‑2 and downregulated phosphorylation of AKT in mesangial cells and improves renal function in lupus nephritis mice. Int J Mol Med. 2018;41:3278-3286 pubmed 出版商
Tankiewicz Kwedlo A, Hermanowicz J, Domaniewski T, Pawlak K, Rusak M, Pryczynicz A, et al. Simultaneous use of erythropoietin and LFM-A13 as a new therapeutic approach for colorectal cancer. Br J Pharmacol. 2017;: pubmed 出版商
Thaler S, Schmidt M, Roβwag S, Thiede G, Schad A, Sleeman J. Proteasome inhibitors prevent bi-directional HER2/estrogen-receptor cross-talk leading to cell death in endocrine and lapatinib-resistant HER2+/ER+ breast cancer cells. Oncotarget. 2017;8:72281-72301 pubmed 出版商
Kong X, Kuilman T, Shahrabi A, Boshuizen J, Kemper K, Song J, et al. Cancer drug addiction is relayed by an ERK2-dependent phenotype switch. Nature. 2017;550:270-274 pubmed 出版商
Skarra D, Hernandez Carretero A, Rivera A, Anvar A, Thackray V. Hyperandrogenemia Induced by Letrozole Treatment of Pubertal Female Mice Results in Hyperinsulinemia Prior to Weight Gain and Insulin Resistance. Endocrinology. 2017;158:2988-3003 pubmed 出版商
Yang Z, Su Z, Dewitt J, Xie L, Chen Y, Li X, et al. Fluvastatin Prevents Lung Adenocarcinoma Bone Metastasis by Triggering Autophagy. EBioMedicine. 2017;19:49-59 pubmed 出版商
Schmukler E, Wolfson E, Elazar Z, Kloog Y, Pinkas Kramarski R. Continuous treatment with FTS confers resistance to apoptosis and affects autophagy. PLoS ONE. 2017;12:e0171351 pubmed 出版商
Fang Q, Guo S, Zhou H, Han R, Wu P, Han C. Astaxanthin protects against early burn-wound progression in rats by attenuating oxidative stress-induced inflammation and mitochondria-related apoptosis. Sci Rep. 2017;7:41440 pubmed 出版商
Wolfson E, Goldenberg M, Solomon S, Frishberg A, Pinkas Kramarski R. Nucleolin-binding by ErbB2 enhances tumorigenicity of ErbB2-positive breast cancer. Oncotarget. 2016;7:65320-65334 pubmed 出版商
Song X, Ding Y, Liu G, Yang X, Zhao R, Zhang Y, et al. Cancer Cell-derived Exosomes Induce Mitogen-activated Protein Kinase-dependent Monocyte Survival by Transport of Functional Receptor Tyrosine Kinases. J Biol Chem. 2016;291:8453-64 pubmed 出版商
Grassi D, Ghorbanpoor S, Acaz Fonseca E, Ruiz Palmero I, Garcia Segura L. The Selective Estrogen Receptor Modulator Raloxifene Regulates Arginine-Vasopressin Gene Expression in Human Female Neuroblastoma Cells Through G Protein-Coupled Estrogen Receptor and ERK Signaling. Endocrinology. 2015;156:3706-16 pubmed 出版商
Khalil H, Peltzer N, Walicki J, Yang J, Dubuis G, Gardiol N, et al. Caspase-3 protects stressed organs against cell death. Mol Cell Biol. 2012;32:4523-33 pubmed 出版商
Bulat N, Jaccard E, Peltzer N, Khalil H, Yang J, Dubuis G, et al. RasGAP-derived fragment N increases the resistance of beta cells towards apoptosis in NOD mice and delays the progression from mild to overt diabetes. PLoS ONE. 2011;6:e22609 pubmed 出版商
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。