产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
p-IkappaB-alpha (B-9) Antibody
目录 :
sc-8404
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
抗原修饰 :
磷酸化
克隆名称 :
B-9
反应物种 :
人类, 小鼠, brown rat
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 69
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 4a
Zoi I, Karamouzis M, Xingi E, Sarantis P, Thomaidou D, Lembessis P, et al. Combining RANK/RANKL and ERBB-2 targeting as a novel strategy in ERBB-2-positive breast carcinomas. Breast Cancer Res. 2019;21:132 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5a
Cho H, Kim J, Jang H, Lee T, Jung M, Kim T, et al. Alpha-lipoic acid ameliorates the epithelial mesenchymal transition induced by unilateral ureteral obstruction in mice. Sci Rep. 2017;7:46065 pubmed 出版商
  • 免疫印迹; 人类; 图 4a
Jiang D, Gao F, Zhang Y, Wong D, Li Q, Tse H, et al. Mitochondrial transfer of mesenchymal stem cells effectively protects corneal epithelial cells from mitochondrial damage. Cell Death Dis. 2016;7:e2467 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 7a
Okabe T, Chavan R, Fonseca Costa S, Brenna A, Ripperger J, Albrecht U. REV-ERB? influences the stability and nuclear localization of the glucocorticoid receptor. J Cell Sci. 2016;129:4143-4154 pubmed
  • 免疫印迹; 人类; 1:400; 图 4
He M, Wang M, Huang Y, Peng W, Zheng Z, Xia N, et al. The ORF3 Protein of Genotype 1 Hepatitis E Virus Suppresses TLR3-induced NF-κB Signaling via TRADD and RIP1. Sci Rep. 2016;6:27597 pubmed 出版商
  • 免疫印迹; brown rat; 1:250; 图 6
Tang S, Su H, Zhang Q, Tang H, Wang C, Zhou Q, et al. Sitagliptin inhibits endothelin-1 expression in the aortic endothelium of rats with streptozotocin-induced diabetes by suppressing the nuclear factor-?B/I?B? system through the activation of AMP-activated protein kinase. Int J Mol Med. 2016;37:1558-66 pubmed 出版商
  • 免疫印迹; 人类; 1:200; 图 1
Tu Q, Xiong Y, Fan L, Qiao B, Xia Z, Hu L, et al. Peroxiredoxin 6 attenuates ischemia‑ and hypoxia‑induced liver damage of brain‑dead donors. Mol Med Rep. 2016;13:753-61 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Sakurikar N, Thompson R, Montano R, Eastman A. A subset of cancer cell lines is acutely sensitive to the Chk1 inhibitor MK-8776 as monotherapy due to CDK2 activation in S phase. Oncotarget. 2016;7:1380-94 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 4
El Khattouti A, Selimovic D, Hannig M, Taylor E, Abd Elmageed Z, Hassan S, et al. Imiquimod-induced apoptosis of melanoma cells is mediated by ER stress-dependent Noxa induction and enhanced by NF-κB inhibition. J Cell Mol Med. 2016;20:266-86 pubmed 出版商
  • 免疫印迹; 小鼠; 图 11b
Singh S, Chhunchha B, Fatma N, Kubo E, Singh S, Singh D. Delivery of a protein transduction domain-mediated Prdx6 protein ameliorates oxidative stress-induced injury in human and mouse neuronal cells. Am J Physiol Cell Physiol. 2016;310:C1-16 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Lavoz C, Alique M, Rodrígues Díez R, Pato J, Keri G, Mezzano S, et al. Gremlin regulates renal inflammation via the vascular endothelial growth factor receptor 2 pathway. J Pathol. 2015;236:407-20 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Liu E, Xu N, O Prey J, Lao L, Joshi S, Long J, et al. Loss of autophagy causes a synthetic lethal deficiency in DNA repair. Proc Natl Acad Sci U S A. 2015;112:773-8 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Chen H, Sohn J, Zhang L, Tian J, Chen S, Bjeldanes L. Anti-inflammatory effects of chicanine on murine macrophage by down-regulating LPS-induced inflammatory cytokines in I?B?/MAPK/ERK signaling pathways. Eur J Pharmacol. 2014;724:168-74 pubmed 出版商
Lin Y, Huang S, Wu J, Chu T, Huang S, Lee C, et al. Novel HDGF/HIF-1α/VEGF axis in oral cancer impacts disease prognosis. BMC Cancer. 2019;19:1083 pubmed 出版商
Choi S, Martínez T, Kim S, Donaldson C, Shokhirev M, Saghatelian A, et al. CDK12 phosphorylates 4E-BP1 to enable mTORC1-dependent translation and mitotic genome stability. Genes Dev. 2019;33:418-435 pubmed 出版商
Choi J, Yeo I, Kim K, Choi W, Jung J, Han S, et al. K284-6111 prevents the amyloid beta-induced neuroinflammation and impairment of recognition memory through inhibition of NF-κB-mediated CHI3L1 expression. J Neuroinflammation. 2018;15:224 pubmed 出版商
Jiang M, Xu C, Guo Y, Luo Q, Li L, Liu H, et al. ?-arrestin 2 attenuates lipopolysaccharide-induced liver injury via inhibition of TLR4/NF-?B signaling pathway-mediated inflammation in mice. World J Gastroenterol. 2018;24:216-225 pubmed 出版商
Lennikov A, Mirabelli P, Mukwaya A, Schaupper M, Thangavelu M, Lachota M, et al. Selective IKK2 inhibitor IMD0354 disrupts NF-κB signaling to suppress corneal inflammation and angiogenesis. Angiogenesis. 2018;21:267-285 pubmed 出版商
Barker E, Kim B, Yoon J, Tochtrop G, Letterio J, Choi S. Potent Suppression of Both Spontaneous and Carcinogen-induced Colitis-associated Colorectal Cancer in Mice by Dietary Celastrol Supplementation. Carcinogenesis. 2017;: pubmed 出版商
Fasano E, Serini S, Mondella N, Trombino S, Celleno L, Lanza P, et al. Antioxidant and anti-inflammatory effects of selected natural compounds contained in a dietary supplement on two human immortalized keratinocyte lines. Biomed Res Int. 2014;2014:327452 pubmed 出版商
Zhu H, Bian C, Yuan J, Chu W, Xiang X, Chen F, et al. Curcumin attenuates acute inflammatory injury by inhibiting the TLR4/MyD88/NF-?B signaling pathway in experimental traumatic brain injury. J Neuroinflammation. 2014;11:59 pubmed 出版商
Yang N, Farrell A, Niedelman W, Melo M, Lu D, Julien L, et al. Genetic basis for phenotypic differences between different Toxoplasma gondii type I strains. BMC Genomics. 2013;14:467 pubmed 出版商
Wang Y, Li C, Pan L, Gao Z. 7,8-Dihydroxycoumarin inhibits A549 human lung adenocarcinoma cell proliferation by inducing apoptosis via suppression of Akt/NF-?B signaling. Exp Ther Med. 2013;5:1770-1774 pubmed
Zara S, De Colli M, Rapino M, Di Valerio V, Marconi G, Cataldi A, et al. NF-?B involvement in hyperoxia-induced myocardial damage in newborn rat hearts. Histochem Cell Biol. 2013;140:575-83 pubmed 出版商
Qin X, Sun Z, Zhang X, Dai X, Mao S, Zhang Y. TLR4 signaling is involved in the protective effect of propofol in BV2 microglia against OGD/reoxygenation. J Physiol Biochem. 2013;69:707-18 pubmed 出版商
Gai L, Cai N, Wang L, Xu X, Kong X. Ursolic acid induces apoptosis via Akt/NF-?B signaling suppression in T24 human bladder cancer cells. Mol Med Rep. 2013;7:1673-7 pubmed 出版商
Kastamoulas M, Chondrogiannis G, Kanavaros P, Vartholomatos G, Bai M, Briasoulis E, et al. Cytokine effects on cell survival and death of A549 lung carcinoma cells. Cytokine. 2013;61:816-25 pubmed 出版商
Chhunchha B, Fatma N, Kubo E, Rai P, Singh S, Singh D. Curcumin abates hypoxia-induced oxidative stress based-ER stress-mediated cell death in mouse hippocampal cells (HT22) by controlling Prdx6 and NF-?B regulation. Am J Physiol Cell Physiol. 2013;304:C636-55 pubmed 出版商
Patruno A, Franceschelli S, Pesce M, Maccallini C, Fantacuzzi M, Speranza L, et al. Novel aminobenzyl-acetamidine derivative modulate the differential regulation of NOSs in LPS induced inflammatory response: role of PI3K/Akt pathway. Biochim Biophys Acta. 2012;1820:2095-104 pubmed 出版商
Bhatt K, Sodhi A, Chakraborty R. Peptidoglycan induced expression of peroxisome proliferator-activated receptor ? in mouse peritoneal macrophages: role of ERK and JNK MAP kinases. Cytokine. 2012;60:778-86 pubmed 出版商
Jiang T, Gao L, Guo J, Lu J, Wang Y, Zhang Y. Suppressing inflammation by inhibiting the NF-?B pathway contributes to the neuroprotective effect of angiotensin-(1-7) in rats with permanent cerebral ischaemia. Br J Pharmacol. 2012;167:1520-32 pubmed 出版商
Qin X, Sun Z, Dai X, Mao S, Zhang J, Jia M, et al. Toll-like receptor 4 signaling is involved in PACAP-induced neuroprotection in BV2 microglial cells under OGD/reoxygenation. Neurol Res. 2012;34:379-89 pubmed 出版商
Mao S, Hua R, Zhao X, Qin X, Sun Z, Zhang Y, et al. Exogenous administration of PACAP alleviates traumatic brain injury in rats through a mechanism involving the TLR4/MyD88/NF-?B pathway. J Neurotrauma. 2012;29:1941-59 pubmed 出版商
Tian F, Zhang C, Tian W, Jiang Y, Zhang X. Comparison of the effect of p65 siRNA and curcumin in promoting apoptosis in esophageal squamous cell carcinoma cells and in nude mice. Oncol Rep. 2012;28:232-40 pubmed 出版商
Ndour P, Brocqueville G, Ouk T, Goormachtigh G, Morales O, Mougel A, et al. Inhibition of latent membrane protein 1 impairs the growth and tumorigenesis of latency II Epstein-Barr virus-transformed T cells. J Virol. 2012;86:3934-43 pubmed 出版商
Tian F, Fan T, Jiang Y, Zhang X, Wang X. A small interfering RNA targeting NF-?B p65 alone or combined with 5-FU inhibits growth of esophageal squamous cell carcinoma in nude mice. Pathol Res Pract. 2012;208:32-8 pubmed 出版商
Park H, Lee J, Chung M, Park Y, Bower A, Koo S, et al. Green tea extract suppresses NF?B activation and inflammatory responses in diet-induced obese rats with nonalcoholic steatohepatitis. J Nutr. 2012;142:57-63 pubmed 出版商
Huang Z, Liang C, HAN S, Wu Z. Vitamin E ameliorates ox-LDL-induced foam cells formation through modulating the activities of oxidative stress-induced NF-?B pathway. Mol Cell Biochem. 2012;363:11-9 pubmed 出版商
Ma X, Yang L, Xiao L, Tang M, Liu L, Li Z, et al. Down-regulation of EBV-LMP1 radio-sensitizes nasal pharyngeal carcinoma cells via NF-κB regulated ATM expression. PLoS ONE. 2011;6:e24647 pubmed 出版商
Wu C, Li T, Hsu S, Su Y, Kao S, Fong Y, et al. IGF-I enhances ?5?1 integrin expression and cell motility in human chondrosarcoma cells. J Cell Physiol. 2011;226:3270-7 pubmed 出版商
Medina Tamayo J, Ibarra Sanchez A, Padilla Trejo A, Gonzalez Espinosa C. IgE-dependent sensitization increases responsiveness to LPS but does not modify development of endotoxin tolerance in mast cells. Inflamm Res. 2011;60:19-27 pubmed 出版商
Gao Z, Zhang D, Guo C. Paclitaxel efficacy is increased by parthenolide via nuclear factor-kappaB pathways in in vitro and in vivo human non-small cell lung cancer models. Curr Cancer Drug Targets. 2010;10:705-15 pubmed
Andújar I, Recio M, Bacelli T, Giner R, Rios J. Shikonin reduces oedema induced by phorbol ester by interfering with IkappaBalpha degradation thus inhibiting translocation of NF-kappaB to the nucleus. Br J Pharmacol. 2010;160:376-88 pubmed 出版商
Jin X, Qiu L, Zhang D, Zhang M, Wang Z, Guo Z, et al. Chemosensitization in non-small cell lung cancer cells by IKK inhibitor occurs via NF-kappaB and mitochondrial cytochrome c cascade. J Cell Mol Med. 2009;13:4596-607 pubmed 出版商
Webster C, Kelly S, Koike M, Chock V, Giffard R, Yenari M. Inflammation and NFkappaB activation is decreased by hypothermia following global cerebral ischemia. Neurobiol Dis. 2009;33:301-12 pubmed 出版商
Zhang Y, Wei E, Hu X, Qiao W, Shi Y, Xu M, et al. The role of nuclear factor-kappaB in the effect of angiotensin II in the paraventricular nucleus in protecting the gastric mucosa from ischemia-reperfusion injury in rats. J Gastroenterol. 2008;43:687-98 pubmed 出版商
Korkolopoulou P, Levidou G, Saetta A, El Habr E, Eftichiadis C, Demenagas P, et al. Expression of nuclear factor-kappaB in human astrocytomas: relation to pI kappa Ba, vascular endothelial growth factor, Cox-2, microvascular characteristics, and survival. Hum Pathol. 2008;39:1143-52 pubmed 出版商
Vu H, Juvekar A, Ghosh C, Ramaswami S, Le D, Vancurova I. Proteasome inhibitors induce apoptosis of prostate cancer cells by inducing nuclear translocation of IkappaBalpha. Arch Biochem Biophys. 2008;475:156-63 pubmed 出版商
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Yu J, Qian H, Li Y, Wang Y, Zhang X, Liang X, et al. Arsenic trioxide (As2O3) reduces the invasive and metastatic properties of cervical cancer cells in vitro and in vivo. Gynecol Oncol. 2007;106:400-6 pubmed
Verkoczy L, Duong B, Skog P, Ait Azzouzene D, Puri K, VELA J, et al. Basal B cell receptor-directed phosphatidylinositol 3-kinase signaling turns off RAGs and promotes B cell-positive selection. J Immunol. 2007;178:6332-41 pubmed
Zheng Z, Kim J, Ma H, Lee J, Yenari M. Anti-inflammatory effects of the 70 kDa heat shock protein in experimental stroke. J Cereb Blood Flow Metab. 2008;28:53-63 pubmed
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Cho H, Morgan D, Bauer A, Kleeberger S. Signal transduction pathways of tumor necrosis factor--mediated lung injury induced by ozone in mice. Am J Respir Crit Care Med. 2007;175:829-39 pubmed
Shimizu S, Tahara M, Ogata S, Hashimoto K, Morishige K, Tasaka K, et al. Involvement of nuclear factor-kB activation through RhoA/Rho-kinase pathway in LPS-induced IL-8 production in human cervical stromal cells. Mol Hum Reprod. 2007;13:181-7 pubmed
Taylor R, Bresnahan W. Human cytomegalovirus IE86 attenuates virus- and tumor necrosis factor alpha-induced NFkappaB-dependent gene expression. J Virol. 2006;80:10763-71 pubmed
Hanashiro K, Sunagawa M, Tokeshi Y, Nakasone T, Ohta S, Nakamura M, et al. Antiallergic drugs, azelastine hydrochloride and epinastine hydrochloride, inhibit ongoing IgE secretion of rat IgE-producing hybridoma FE-3 cells. Eur J Pharmacol. 2006;547:174-83 pubmed
Hafeez B, Ahmed S, Wang N, Gupta S, Zhang A, Haqqi T. Green tea polyphenols-induced apoptosis in human osteosarcoma SAOS-2 cells involves a caspase-dependent mechanism with downregulation of nuclear factor-kappaB. Toxicol Appl Pharmacol. 2006;216:11-9 pubmed
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Wang X, Hu B, Weiss R, Wang Y. The effect of Hus1 on ionizing radiation sensitivity is associated with homologous recombination repair but is independent of nonhomologous end-joining. Oncogene. 2006;25:1980-3 pubmed
Hu B, Wang H, Wang X, Lu H, Huang C, Powell S, et al. Fhit and CHK1 have opposing effects on homologous recombination repair. Cancer Res. 2005;65:8613-6 pubmed
Fang C, Bernardes Silva M, Coleman M, Perry V. The cellular distribution of the Wld s chimeric protein and its constituent proteins in the CNS. Neuroscience. 2005;135:1107-18 pubmed
Mun H, Aosai F, Norose K, Piao L, Fang H, Akira S, et al. Toll-like receptor 4 mediates tolerance in macrophages stimulated with Toxoplasma gondii-derived heat shock protein 70. Infect Immun. 2005;73:4634-42 pubmed
Cho H, Jedlicka A, Clarke R, Kleeberger S. Role of Toll-like receptor-4 in genetic susceptibility to lung injury induced by residual oil fly ash. Physiol Genomics. 2005;22:108-17 pubmed
Yagyu T, Kobayashi H, Matsuzaki H, Wakahara K, Kondo T, Kurita N, et al. Thalidomide inhibits tumor necrosis factor-alpha-induced interleukin-8 expression in endometriotic stromal cells, possibly through suppression of nuclear factor-kappaB activation. J Clin Endocrinol Metab. 2005;90:3017-21 pubmed
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Wang H, Hu B, Liu R, Wang Y. CHK1 affecting cell radiosensitivity is independent of non-homologous end joining. Cell Cycle. 2005;4:300-3 pubmed
Lysiak J, Bang H, Nguyen Q, Turner T. Activation of the nuclear factor kappa B pathway following ischemia-reperfusion of the murine testis. J Androl. 2005;26:129-35 pubmed
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产品信息
产品名称 :
p-IkappaB-alpha (B-9) Antibody
基因名称 :
NFKBIA
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-8404
修饰 :
phosporylated
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
p-IkappaB-alpha
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P)
表位 :
Ser 32 (h)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。