产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
TRAF6(D-10)抗体
目录 :
sc-8409
规格 :
200微克/毫升
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
D-10
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 33
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 3e
Kim M, Kim J, Hong S, Kwon B, Kim E, Jung H, et al. Effects of Melandrium firmum Rohrbach on RANKL‑induced osteoclast differentiation and OVX rats. Mol Med Rep. 2021;24: pubmed 出版商
  • 免疫印迹; 小鼠; 图 2d
Du T, Yan Z, Zhu S, Chen G, Wang L, Ye Z, et al. QKI deficiency leads to osteoporosis by promoting RANKL-induced osteoclastogenesis and disrupting bone metabolism. Cell Death Dis. 2020;11:330 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1c
Kim Y, Kim J, Gu S, Jo S, Kim S, Young Kim S, et al. Identification of highly potent and selective inhibitor, TIPTP, of the p22phox-Rubicon axis as a therapeutic agent for rheumatoid arthritis. Sci Rep. 2020;10:4570 pubmed 出版商
  • 免疫沉淀; 大鼠; 1:200; 图 4a
  • 免疫印迹; 大鼠; 1:200; 图 3b
Peng L, Zhou Y, Jiang N, Wang T, Zhu J, Chen Y, et al. DJ-1 exerts anti-inflammatory effects and regulates NLRX1-TRAF6 via SHP-1 in stroke. J Neuroinflammation. 2020;17:81 pubmed 出版商
  • 免疫印迹; 人类; 图 5d
Xu G, Xia Z, Deng F, Liu L, Wang Q, Yu Y, et al. Inducible LGALS3BP/90K activates antiviral innate immune responses by targeting TRAF6 and TRAF3 complex. PLoS Pathog. 2019;15:e1008002 pubmed 出版商
  • 免疫印迹; 人类; 图 4e
Liu P, Shah R, Li Y, Arora A, Ung P, Raman R, et al. An IRAK1-PIN1 signalling axis drives intrinsic tumour resistance to radiation therapy. Nat Cell Biol. 2019;21:203-213 pubmed 出版商
  • 免疫印迹; 人类
Ma C, Lin W, Liu Z, Tang W, Gautam R, Li H, et al. NDR1 protein kinase promotes IL-17- and TNF-α-mediated inflammation by competitively binding TRAF3. EMBO Rep. 2017;18:586-602 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100
  • 免疫印迹; 人类; 1:1000; 图 3e
Lu W, Liu S, Li B, Xie Y, Izban M, Ballard B, et al. SKP2 loss destabilizes EZH2 by promoting TRAF6-mediated ubiquitination to suppress prostate cancer. Oncogene. 2017;36:1364-1373 pubmed 出版商
  • 免疫印迹; 大鼠; 图 3a
Stucky A, Bakshi K, Friedman E, Wang H. Prenatal Cocaine Exposure Upregulates BDNF-TrkB Signaling. PLoS ONE. 2016;11:e0160585 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 5a
Kinsella S, König H, Prehn J. Bid Promotes K63-Linked Polyubiquitination of Tumor Necrosis Factor Receptor Associated Factor 6 (TRAF6) and Sensitizes to Mutant SOD1-Induced Proinflammatory Signaling in Microglia. Eneuro. 2016;3: pubmed 出版商
  • 免疫印迹; 人类; 图 6n
Wu H, Hwang Verslues W, Lee W, Huang C, Wei P, Chen C, et al. Targeting IL-17B-IL-17RB signaling with an anti-IL-17RB antibody blocks pancreatic cancer metastasis by silencing multiple chemokines. J Exp Med. 2015;212:333-49 pubmed 出版商
  • 免疫沉淀; 人类; 1:20
  • 免疫印迹; 人类; 1:200
Cañeda Guzmán I, Salaiza Suazo N, Fernández Figueroa E, Carrada Figueroa G, Aguirre García M, Becker I. NK cell activity differs between patients with localized and diffuse cutaneous leishmaniasis infected with Leishmania mexicana: a comparative study of TLRs and cytokines. PLoS ONE. 2014;9:e112410 pubmed 出版商
  • 免疫沉淀; 小鼠; 2 ug
  • 免疫印迹; 小鼠; 1:1000
Yu B, Chang J, Liu Y, Li J, Kevork K, Al Hezaimi K, et al. Wnt4 signaling prevents skeletal aging and inflammation by inhibiting nuclear factor-?B. Nat Med. 2014;20:1009-17 pubmed 出版商
  • 免疫印迹; 人类
van Gent M, Braem S, de Jong A, Delagic N, Peeters J, Boer I, et al. Epstein-Barr virus large tegument protein BPLF1 contributes to innate immune evasion through interference with toll-like receptor signaling. PLoS Pathog. 2014;10:e1003960 pubmed 出版商
  • 免疫沉淀; 人类
  • 免疫印迹; 人类; 1:1000
Huang C, Yang C, Jeng Y, Chen C, Wu H, Chang Y, et al. Autocrine/paracrine mechanism of interleukin-17B receptor promotes breast tumorigenesis through NF-?B-mediated antiapoptotic pathway. Oncogene. 2014;33:2968-77 pubmed 出版商
Liao H, Zhang N, Meng Y, Feng H, Yang J, Li W, et al. Myricetin Alleviates Pathological Cardiac Hypertrophy via TRAF6/TAK1/MAPK and Nrf2 Signaling Pathway. Oxid Med Cell Longev. 2019;2019:6304058 pubmed 出版商
Arora H, Wilcox S, Johnson L, Munro L, Eyford B, Pfeifer C, et al. The ATP-Binding Cassette Gene ABCF1 Functions as an E2 Ubiquitin-Conjugating Enzyme Controlling Macrophage Polarization to Dampen Lethal Septic Shock. Immunity. 2019;50:418-431.e6 pubmed 出版商
Liu J, Yuan Y, Xu J, Xiao K, Xu Y, Guo T, et al. β-TrCP Restricts Lipopolysaccharide (LPS)-Induced Activation of TRAF6-IKK Pathway Upstream of IκBα Signaling. Front Immunol. 2018;9:2930 pubmed 出版商
Luong P, Hedl M, Yan J, Zuo T, Fu T, Jiang X, et al. INAVA-ARNO complexes bridge mucosal barrier function with inflammatory signaling. elife. 2018;7: pubmed 出版商
Tin A, Park A, Sundar S, Firestone G. Essential role of the cancer stem/progenitor cell marker nucleostemin for indole-3-carbinol anti-proliferative responsiveness in human breast cancer cells. BMC Biol. 2014;12:72 pubmed 出版商
Liu L, Gu H, Liu H, Jiao Y, Li K, Zhao Y, et al. Protective effect of resveratrol against IL-1?-induced inflammatory response on human osteoarthritic chondrocytes partly via the TLR4/MyD88/NF-?B signaling pathway: an "in vitro study". Int J Mol Sci. 2014;15:6925-40 pubmed 出版商
Yao L, Kan E, Kaur C, Dheen S, Hao A, Lu J, et al. Notch-1 signaling regulates microglia activation via NF-?B pathway after hypoxic exposure in vivo and in vitro. PLoS ONE. 2013;8:e78439 pubmed 出版商
Lin X, Xu W, Luo J, Guo X, Sun T, Zhao X, et al. WW domain containing E3 ubiquitin protein ligase 1 (WWP1) negatively regulates TLR4-mediated TNF-? and IL-6 production by proteasomal degradation of TNF receptor associated factor 6 (TRAF6). PLoS ONE. 2013;8:e67633 pubmed 出版商
Takamatsu S, Onoguchi K, Onomoto K, Narita R, Takahasi K, Ishidate F, et al. Functional characterization of domains of IPS-1 using an inducible oligomerization system. PLoS ONE. 2013;8:e53578 pubmed 出版商
Tateda K, Okazaki S, Nagoya S, Katada R, Mizuo K, Watanabe S, et al. The suppression of TRIM21 and the accumulation of IFN-? play crucial roles in the pathogenesis of osteonecrosis of the femoral head. Lab Invest. 2012;92:1318-29 pubmed 出版商
Cheng J, Liu J, Shi Z, Jules J, Xu D, Luo S, et al. Molecular mechanisms of the biphasic effects of interferon-? on osteoclastogenesis. J Interferon Cytokine Res. 2012;32:34-45 pubmed 出版商
Huang Y, Liu H, Ge R, Zhou Y, Lou X, Wang C. UXT-V1 facilitates the formation of MAVS antiviral signalosome on mitochondria. J Immunol. 2012;188:358-66 pubmed 出版商
Zucchelli S, Marcuzzi F, Codrich M, Agostoni E, Vilotti S, Biagioli M, et al. Tumor necrosis factor receptor-associated factor 6 (TRAF6) associates with huntingtin protein and promotes its atypical ubiquitination to enhance aggregate formation. J Biol Chem. 2011;286:25108-17 pubmed 出版商
Kenchappa R, Tep C, Korade Z, Urra S, Bronfman F, Yoon S, et al. p75 neurotrophin receptor-mediated apoptosis in sympathetic neurons involves a biphasic activation of JNK and up-regulation of tumor necrosis factor-alpha-converting enzyme/ADAM17. J Biol Chem. 2010;285:20358-68 pubmed 出版商
Bhaumik D, Scott G, Schokrpur S, Patil C, Orjalo A, Rodier F, et al. MicroRNAs miR-146a/b negatively modulate the senescence-associated inflammatory mediators IL-6 and IL-8. Aging (Albany NY). 2009;1:402-11 pubmed
Pacifico F, Crescenzi E, Mellone S, Iannetti A, Porrino N, Liguoro D, et al. Nuclear factor-{kappa}B contributes to anaplastic thyroid carcinomas through up-regulation of miR-146a. J Clin Endocrinol Metab. 2010;95:1421-30 pubmed 出版商
McCully R, Pomerantz J. The protein kinase C-responsive inhibitory domain of CARD11 functions in NF-kappaB activation to regulate the association of multiple signaling cofactors that differentially depend on Bcl10 and MALT1 for association. Mol Cell Biol. 2008;28:5668-86 pubmed 出版商
Wang S, Shi Z, Liu W, Jules J, Feng X. Development and validation of vectors containing multiple siRNA expression cassettes for maximizing the efficiency of gene silencing. BMC Biotechnol. 2006;6:50 pubmed
产品信息
产品名称 :
TRAF6(D-10)抗体
基因名称 :
TRAF6
规格 :
200微克/毫升
目录号 :
sc-8409
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
TRAF6
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), 酶联免疫吸附测定
表位 :
1-274(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。