产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
p53(多克隆抗体1801)抗体
目录 :
sc-98
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
多克隆抗体1801
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪, 染色质免疫沉淀 , 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 51
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 1:200; 图 s5b
Goodman D, Pretto C, Krepostman T, Carnahan K, Spindler K. Enhanced Replication of Mouse Adenovirus Type 1 following Virus-Induced Degradation of Protein Kinase R (PKR). MBio. 2019;10: pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 7a
Li R, Sahu S, Schachner M. Phenelzine, a small organic compound mimicking the functions of cell adhesion molecule L1, promotes functional recovery after mouse spinal cord injury. Restor Neurol Neurosci. 2018;36:469-483 pubmed 出版商
  • 免疫印迹; 人类; 1:3000; 图 1d
Liu W, Huang K, Lu M, Huang H, Chen C, Cheng Y, et al. TGF-β upregulates the translation of USP15 via the PI3K/AKT pathway to promote p53 stability. Oncogene. 2017;36:2715-2723 pubmed 出版商
  • 免疫沉淀; 人类; 图 2g
  • 免疫印迹; 人类; 图 4a
Luo H, Cowen L, Yu G, Jiang W, Tang Y. SMG7 is a critical regulator of p53 stability and function in DNA damage stress response. Cell Discov. 2016;2:15042 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6
Kobayashi K, Tsugami Y, Matsunaga K, Oyama S, Kuki C, Kumura H. Prolactin and glucocorticoid signaling induces lactation-specific tight junctions concurrent with ?-casein expression in mammary epithelial cells. Biochim Biophys Acta. 2016;1863:2006-16 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Katoh I, Fukunishi N, Fujimuro M, Kasai H, Moriishi K, Hata R, et al. Repression of Wnt/β-catenin response elements by p63 (TP63). Cell Cycle. 2016;15:699-710 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Du C, Wu H, Leng R. UBE4B targets phosphorylated p53 at serines 15 and 392 for degradation. Oncotarget. 2016;7:2823-36 pubmed 出版商
  • 免疫印迹; 人类; 1:500; 图 6
Vétillard A, Jonchère B, Moreau M, Toutain B, Henry C, Fontanel S, et al. Akt inhibition improves irinotecan treatment and prevents cell emergence by switching the senescence response to apoptosis. Oncotarget. 2015;6:43342-62 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3
  • 免疫印迹; 人类; 图 3
Crivellaro S, Panuzzo C, Carrà G, Volpengo A, Crasto F, Gottardi E, et al. Non genomic loss of function of tumor suppressors in CML: BCR-ABL promotes IκBα mediated p53 nuclear exclusion. Oncotarget. 2015;6:25217-25 pubmed 出版商
  • 免疫细胞化学; 人类
Bishop R, Valle Oseguera C, Spencer J. Human Cytomegalovirus interleukin-10 promotes proliferation and migration of MCF-7 breast cancer cells. Cancer Cell Microenviron. 2015;2: pubmed
  • 免疫印迹; 人类; 1:500; 图 3
Mahale S, Bharate S, Manda S, Joshi P, Jenkins P, Vishwakarma R, et al. Antitumour potential of BPT: a dual inhibitor of cdk4 and tubulin polymerization. Cell Death Dis. 2015;6:e1743 pubmed 出版商
  • 染色质免疫沉淀 ; 人类; 图 3b
  • 免疫印迹; 人类; 图 1f
Wang X, Docanto M, Sasano H, Lo C, Simpson E, Brown K. Prostaglandin E2 inhibits p53 in human breast adipose stromal cells: a novel mechanism for the regulation of aromatase in obesity and breast cancer. Cancer Res. 2015;75:645-55 pubmed 出版商
  • 免疫印迹; 人类
Weilbacher A, Gutekunst M, Oren M, Aulitzky W, van der Kuip H. RITA can induce cell death in p53-defective cells independently of p53 function via activation of JNK/SAPK and p38. Cell Death Dis. 2014;5:e1318 pubmed 出版商
Chang C, Kuo C, Ito T, Su Y, Jiang S, Chiu M, et al. CK1? ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation. Proc Natl Acad Sci U S A. 2017;114:E8035-E8044 pubmed 出版商
Wiechmann S, Gärtner A, Kniss A, Stengl A, Behrends C, Rogov V, et al. Site-specific inhibition of the small ubiquitin-like modifier (SUMO)-conjugating enzyme Ubc9 selectively impairs SUMO chain formation. J Biol Chem. 2017;292:15340-15351 pubmed 出版商
Min J, Wright W, Shay J. Alternative Lengthening of Telomeres Mediated by Mitotic DNA Synthesis Engages Break-Induced Replication Processes. Mol Cell Biol. 2017;37: pubmed 出版商
Min M, Chen X, Wang P, Landeck L, Chen J, Li W, et al. Role of keratin 24 in human epidermal keratinocytes. PLoS ONE. 2017;12:e0174626 pubmed 出版商
Yao C, Chow J, Lin P, Hu T, Kuo H, Huang J, et al. Activation of p53/miR-34a Tumor Suppressor Axis by Chinese Herbal Formula JP-1 in A549 Lung Adenocarcinoma Cells. Evid Based Complement Alternat Med. 2016;2016:5989681 pubmed 出版商
Vaughan C, Pearsall I, Singh S, Windle B, Deb S, Grossman S, et al. Addiction of lung cancer cells to GOF p53 is promoted by up-regulation of epidermal growth factor receptor through multiple contacts with p53 transactivation domain and promoter. Oncotarget. 2016;7:12426-46 pubmed 出版商
Chand H, Montaño G, Huang X, Randell S, Mebratu Y, Petersen H, et al. A genetic variant of p53 restricts the mucous secretory phenotype by regulating SPDEF and Bcl-2 expression. Nat Commun. 2014;5:5567 pubmed 出版商
Huang Y, Bulavin D. Oncogene-mediated regulation of p53 ISGylation and functions. Oncotarget. 2014;5:5808-18 pubmed
Bassères D, Ebbs A, Cogswell P, Baldwin A. IKK is a therapeutic target in KRAS-Induced lung cancer with disrupted p53 activity. Genes Cancer. 2014;5:41-55 pubmed
Loughery J, Cox M, Smith L, Meek D. Critical role for p53-serine 15 phosphorylation in stimulating transactivation at p53-responsive promoters. Nucleic Acids Res. 2014;42:7666-80 pubmed 出版商
Tengku Ahmad T, Jaafar F, Jubri Z, Abdul Rahim K, Rajab N, Makpol S. Gelam honey attenuated radiation-induced cell death in human diploid fibroblasts by promoting cell cycle progression and inhibiting apoptosis. BMC Complement Altern Med. 2014;14:108 pubmed 出版商
Contreras A, Mebratu Y, Delgado M, Montaño G, Hu C, Ryter S, et al. Deacetylation of p53 induces autophagy by suppressing Bmf expression. J Cell Biol. 2013;201:427-37 pubmed 出版商
Cai B, Hsu P, Hsin I, Chao C, Lu M, Lin H, et al. p53 acts as a co-repressor to regulate keratin 14 expression during epidermal cell differentiation. PLoS ONE. 2012;7:e41742 pubmed 出版商
Thomas M, Luchelli L, Pascual M, Gottifredi V, Boccaccio G. A monoclonal antibody against p53 cross-reacts with processing bodies. PLoS ONE. 2012;7:e36447 pubmed 出版商
Rahman M, Zhang Z, Mody A, Su D, Das H. Intraperitoneal injection of JNK-specific inhibitor SP600125 inhibits the expression of presenilin-1 and Notch signaling in mouse brain without induction of apoptosis. Brain Res. 2012;1448:117-28 pubmed 出版商
Bansal N, Kadamb R, Mittal S, Vig L, Sharma R, Dwarakanath B, et al. Tumor suppressor protein p53 recruits human Sin3B/HDAC1 complex for down-regulation of its target promoters in response to genotoxic stress. PLoS ONE. 2011;6:e26156 pubmed 出版商
Lenos K, de Lange J, Teunisse A, Lodder K, Verlaan de Vries M, Wiercinska E, et al. Oncogenic functions of hMDMX in in vitro transformation of primary human fibroblasts and embryonic retinoblasts. Mol Cancer. 2011;10:111 pubmed 出版商
Goñi Oliver P, Avila J, Hernandez F. Calpain regulates N-terminal interaction of GSK-3? with 14-3-3?, p53 and PKB but not with axin. Neurochem Int. 2011;59:97-100 pubmed 出版商
Wang X, Wang J, Jiang X. MdmX protein is essential for Mdm2 protein-mediated p53 polyubiquitination. J Biol Chem. 2011;286:23725-34 pubmed 出版商
Meissner J, FREUND R, Krone D, Umeda P, Chang K, Gros G, et al. Extracellular signal-regulated kinase 1/2-mediated phosphorylation of p300 enhances myosin heavy chain I/beta gene expression via acetylation of nuclear factor of activated T cells c1. Nucleic Acids Res. 2011;39:5907-25 pubmed 出版商
Midde K, Batchinsky A, Cancio L, Shetty S, Komissarov A, Florova G, et al. Wood bark smoke induces lung and pleural plasminogen activator inhibitor 1 and stabilizes its mRNA in porcine lung cells. Shock. 2011;36:128-37 pubmed 出版商
Renault V, Thekkat P, Hoang K, White J, Brady C, Kenzelmann Broz D, et al. The pro-longevity gene FoxO3 is a direct target of the p53 tumor suppressor. Oncogene. 2011;30:3207-21 pubmed 出版商
Liu X, Yang J, Zhang S, Liu X, Liu D. Induction of cell cycle arrest at G1 and S phases and cAMP-dependent differentiation in C6 glioma by low concentration of cycloheximide. BMC Cancer. 2010;10:684 pubmed 出版商
Smoak K, Aloor J, Madenspacher J, Merrick B, Collins J, Zhu X, et al. Myeloid differentiation primary response protein 88 couples reverse cholesterol transport to inflammation. Cell Metab. 2010;11:493-502 pubmed 出版商
Eby K, Rosenbluth J, Mays D, Marshall C, Barton C, Sinha S, et al. ISG20L1 is a p53 family target gene that modulates genotoxic stress-induced autophagy. Mol Cancer. 2010;9:95 pubmed 出版商
Aylon Y, Yabuta N, Besserglick H, Buganim Y, Rotter V, Nojima H, et al. Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation. Oncogene. 2009;28:4469-79 pubmed 出版商
Kim C, Jung S, Naqvi A, Hoffman T, Dericco J, Yamamori T, et al. p53 impairs endothelium-dependent vasomotor function through transcriptional upregulation of p66shc. Circ Res. 2008;103:1441-50 pubmed 出版商
Gochhait S, Dar S, Pal R, Gupta P, Bamezai R. Expression of DNA damage response genes indicate progressive breast tumors. Cancer Lett. 2009;273:305-11 pubmed 出版商
Maimets T, Neganova I, Armstrong L, Lako M. Activation of p53 by nutlin leads to rapid differentiation of human embryonic stem cells. Oncogene. 2008;27:5277-87 pubmed 出版商
Reamon Buettner S, Ciribilli Y, Inga A, Borlak J. A loss-of-function mutation in the binding domain of HAND1 predicts hypoplasia of the human hearts. Hum Mol Genet. 2008;17:1397-405 pubmed 出版商
Saito T, Hama S, Izumi H, Yamasaki F, Kajiwara Y, Matsuura S, et al. Centrosome amplification induced by survivin suppression enhances both chromosome instability and radiosensitivity in glioma cells. Br J Cancer. 2008;98:345-55 pubmed 出版商
Yosifov D, Dineva I, Zaharieva M, Konstantinov S, Berger M. The expression level of the tumor suppressor retinoblastoma protein (Rb) influences the antileukemic efficacy of erucylphospho-N,N,N-trimethylpropylammonium (ErPC3). Cancer Biol Ther. 2007;6:930-5 pubmed
Kennedy R, Chen C, Stuckert P, Archila E, De la Vega M, Moreau L, et al. Fanconi anemia pathway-deficient tumor cells are hypersensitive to inhibition of ataxia telangiectasia mutated. J Clin Invest. 2007;117:1440-9 pubmed
Jackson R, Cho Y, Stein S, Liang P. CYFIP2, a direct p53 target, is leptomycin-B sensitive. Cell Cycle. 2007;6:95-103 pubmed
Alves da Costa C, Sunyach C, Pardossi Piquard R, Sevalle J, Vincent B, Boyer N, et al. Presenilin-dependent gamma-secretase-mediated control of p53-associated cell death in Alzheimer's disease. J Neurosci. 2006;26:6377-85 pubmed
Fu X, Ravindranath L, Tran N, Petrovics G, Srivastava S. Regulation of apoptosis by a prostate-specific and prostate cancer-associated noncoding gene, PCGEM1. DNA Cell Biol. 2006;25:135-41 pubmed
Le H, Minn A, Massague J. Cyclin-dependent kinase inhibitors uncouple cell cycle progression from mitochondrial apoptotic functions in DNA-damaged cancer cells. J Biol Chem. 2005;280:32018-25 pubmed
Fan X, Liu Y, Chen J. Down-regulation of p21 contributes to apoptosis induced by HPV E6 in human mammary epithelial cells. Apoptosis. 2005;10:63-73 pubmed
产品信息
产品名称 :
p53(多克隆抗体1801)抗体
基因名称 :
TP53
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-98
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
p53
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀, IF, 免疫组化(P), FCM
表位 :
32-79(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。