产品简要
公司名称 :
圣克鲁斯生物技术
产品类型 :
抗体
产品名称 :
p53(多克隆抗体240)抗体
目录 :
sc-99
规格 :
200微克/毫升
价格 :
279美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
多克隆抗体240
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 免疫印迹基因敲除验证
更多信息或购买 :
文章摘录数: 77
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 4g
Liao M, Zhao X, Chang S, Lo C, Chenier I, Takano T, et al. AT2 R deficiency mediated podocyte loss via activation of ectopic hedgehog interacting protein (Hhip) gene expression. J Pathol. 2017;243:279-293 pubmed 出版商
  • 免疫印迹基因敲除验证; 人类; 图 5c
Iltzsche F, Simon K, Stopp S, Pattschull G, Francke S, Wolter P, et al. An important role for Myb-MuvB and its target gene KIF23 in a mouse model of lung adenocarcinoma. Oncogene. 2017;36:110-121 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Schiffmacher A, Xie V, Taneyhill L. Cadherin-6B proteolysis promotes the neural crest cell epithelial-to-mesenchymal transition through transcriptional regulation. J Cell Biol. 2016;215:735-747 pubmed
  • 免疫沉淀; 人类; 图 7d
  • 免疫细胞化学; 人类; 1:2000; 图 6g
Parrales A, Ranjan A, Iyer S, Padhye S, Weir S, Roy A, et al. DNAJA1 controls the fate of misfolded mutant p53 through the mevalonate pathway. Nat Cell Biol. 2016;18:1233-1243 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 s11
Wang H, Lööf S, Borg P, Nader G, Blau H, Simon A. Turning terminally differentiated skeletal muscle cells into regenerative progenitors. Nat Commun. 2015;6:7916 pubmed 出版商
  • 免疫印迹; 人类; 1:500
Salm F, Dimitrova V, von Bueren A, Ćwiek P, Rehrauer H, Djonov V, et al. The Phosphoinositide 3-Kinase p110α Isoform Regulates Leukemia Inhibitory Factor Receptor Expression via c-Myc and miR-125b to Promote Cell Proliferation in Medulloblastoma. PLoS ONE. 2015;10:e0123958 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2000; 图 4a
Torma F, Koltai E, Nagy E, Ziaaldini M, Posa A, Koch L, et al. Exercise Increases Markers of Spermatogenesis in Rats Selectively Bred for Low Running Capacity. PLoS ONE. 2014;9:e114075 pubmed 出版商
  • 免疫印迹; 人类
  • 免疫印迹; 小鼠
Vassilopoulos A, Tominaga Y, Kim H, Lahusen T, Li B, Yu H, et al. WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis. Oncogene. 2015;34:3023-35 pubmed 出版商
  • 免疫印迹; 小鼠
Brown D, LASSEGUE B, Lee M, Zafari R, Long J, Saavedra H, et al. Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts. PLoS ONE. 2014;9:e96657 pubmed 出版商
  • 免疫印迹; 人类
Milićević Z, Bajic V, Zivkovic L, Kasapović J, Andjelković U, Spremo Potparevic B. Identification of p53 and its isoforms in human breast carcinoma cells. ScientificWorldJournal. 2014;2014:618698 pubmed 出版商
  • 免疫印迹; 人类
Meng L, Kohn K, Pommier Y. Dose-response transition from cell cycle arrest to apoptosis with selective degradation of Mdm2 and p21WAF1/CIP1 in response to the novel anticancer agent, aminoflavone (NSC 686,288). Oncogene. 2007;26:4806-16 pubmed
  • 免疫印迹; 小鼠; 1:500; 图 1a
Christmann M, Tomicic M, Origer J, Aasland D, Kaina B. c-Fos is required for excision repair of UV-light induced DNA lesions by triggering the re-synthesis of XPF. Nucleic Acids Res. 2006;34:6530-9 pubmed
  • 免疫印迹; 小鼠
Moorthy A, Savinova O, Ho J, Wang V, Vu D, Ghosh G. The 20S proteasome processes NF-kappaB1 p105 into p50 in a translation-independent manner. EMBO J. 2006;25:1945-56 pubmed
Li H, Gao Q, Shao Y, Sun B, Wang F, Qiao Y, et al. Gallid Herpesvirus 1 Initiates Apoptosis in Uninfected Cells through Paracrine Repression of p53. J Virol. 2018;92: pubmed 出版商
Cencioni C, Spallotta F, Savoia M, Kuenne C, Guenther S, Re A, et al. Zeb1-Hdac2-eNOS circuitry identifies early cardiovascular precursors in naive mouse embryonic stem cells. Nat Commun. 2018;9:1281 pubmed 出版商
Chen P, Li D, Chen Y, Sun J, Fu K, Guan L, et al. p53-mediated regulation of bile acid disposition attenuates cholic acid-induced cholestasis in mice. Br J Pharmacol. 2017;174:4345-4361 pubmed 出版商
Shin C, Lee M, Han J, Jeong S, Ryu B, Chi S. Identification of XAF1-MT2A mutual antagonism as a molecular switch in cell-fate decisions under stressful conditions. Proc Natl Acad Sci U S A. 2017;114:5683-5688 pubmed 出版商
Wang G, Fersht A. Multisite aggregation of p53 and implications for drug rescue. Proc Natl Acad Sci U S A. 2017;114:E2634-E2643 pubmed 出版商
Justiniano R, Williams J, Perer J, Hua A, Lesson J, Park S, et al. The B6 -vitamer Pyridoxal is a Sensitizer of UVA-induced Genotoxic Stress in Human Primary Keratinocytes and Reconstructed Epidermis. Photochem Photobiol. 2017;93:990-998 pubmed 出版商
Guan Y, Huang D, Chen F, Gao C, Tao T, Shi H, et al. Phosphorylation of Def Regulates Nucleolar p53 Turnover and Cell Cycle Progression through Def Recruitment of Calpain3. PLoS Biol. 2016;14:e1002555 pubmed 出版商
Jørgensen M, Bæk R, Varming K. Potentials and capabilities of the Extracellular Vesicle (EV) Array. J Extracell Vesicles. 2015;4:26048 pubmed 出版商
Munne P, Gu Y, Tumiati M, Gao P, Koopal S, Uusivirta S, et al. TP53 supports basal-like differentiation of mammary epithelial cells by preventing translocation of deltaNp63 into nucleoli. Sci Rep. 2014;4:4663 pubmed 出版商
Sunico C, Nakamura T, Rockenstein E, Mante M, Adame A, Chan S, et al. S-Nitrosylation of parkin as a novel regulator of p53-mediated neuronal cell death in sporadic Parkinson's disease. Mol Neurodegener. 2013;8:29 pubmed 出版商
Suman S, Rodriguez O, Winters T, Fornace A, Albanese C, Datta K. Therapeutic and space radiation exposure of mouse brain causes impaired DNA repair response and premature senescence by chronic oxidant production. Aging (Albany NY). 2013;5:607-22 pubmed
Montagnaro S, Ciarcia R, de Martinis C, Pacilio C, Sasso S, Puzio M, et al. Modulation of apoptosis by caprine herpesvirus 1 infection in a neuronal cell line. J Cell Biochem. 2013;114:2809-22 pubmed 出版商
Estrada J, Torres Y, Benguria A, Dopazo A, Roche E, Carrera Quintanar L, et al. Human mesenchymal stem cell-replicative senescence and oxidative stress are closely linked to aneuploidy. Cell Death Dis. 2013;4:e691 pubmed 出版商
Othman E, Kreissl M, Kaiser F, Arias Loza P, Stopper H. Insulin-mediated oxidative stress and DNA damage in LLC-PK1 pig kidney cell line, female rat primary kidney cells, and male ZDF rat kidneys in vivo. Endocrinology. 2013;154:1434-43 pubmed 出版商
Kazmi S, Byer S, Eckert J, Turk A, Huijbregts R, Brossier N, et al. Transgenic mice overexpressing neuregulin-1 model neurofibroma-malignant peripheral nerve sheath tumor progression and implicate specific chromosomal copy number variations in tumorigenesis. Am J Pathol. 2013;182:646-67 pubmed 出版商
Rieber M, Strasberg Rieber M. Hypoxia, Mn-SOD and H(2)O(2) regulate p53 reactivation and PRIMA-1 toxicity irrespective of p53 status in human breast cancer cells. Biochem Pharmacol. 2012;84:1563-70 pubmed 出版商
Cotrim C, Fabris V, Doria M, Lindberg K, Gustafsson J, Amado F, et al. Estrogen receptor beta growth-inhibitory effects are repressed through activation of MAPK and PI3K signalling in mammary epithelial and breast cancer cells. Oncogene. 2013;32:2390-402 pubmed 出版商
Muttray A, Reinisch C, Miller J, Ernst W, Gillis P, Losier M, et al. Haemocytic leukemia in Prince Edward Island (PEI) soft shell clam (Mya arenaria): spatial distribution in agriculturally impacted estuaries. Sci Total Environ. 2012;424:130-42 pubmed 出版商
Fiorito F, Ciarcia R, Granato G, Marfe G, Iovane V, Florio S, et al. 2,3,7,8-tetrachlorodibenzo-p-dioxin induced autophagy in a bovine kidney cell line. Toxicology. 2011;290:258-70 pubmed 出版商
Chavez Perez V, Strasberg Rieber M, Rieber M. Metabolic utilization of exogenous pyruvate by mutant p53 (R175H) human melanoma cells promotes survival under glucose depletion. Cancer Biol Ther. 2011;12:647-56 pubmed
Mannava S, Omilian A, Wawrzyniak J, Fink E, Zhuang D, Miecznikowski J, et al. PP2A-B56? controls oncogene-induced senescence in normal and tumor human melanocytic cells. Oncogene. 2012;31:1484-92 pubmed 出版商
Heiber J, Barber G. Vesicular stomatitis virus expressing tumor suppressor p53 is a highly attenuated, potent oncolytic agent. J Virol. 2011;85:10440-50 pubmed 出版商
Xu S, Jiang B, Hou X, Shi C, Bachschmid M, Zang M, et al. High-fat diet increases and the polyphenol, S17834, decreases acetylation of the sirtuin-1-dependent lysine-382 on p53 and apoptotic signaling in atherosclerotic lesion-prone aortic endothelium of normal mice. J Cardiovasc Pharmacol. 2011;58:263-71 pubmed 出版商
Wang L, Rodrigues N, Wu Y, Maslikowski B, Singh N, Lacroix S, et al. Pleiotropic action of AP-1 in v-Src-transformed cells. J Virol. 2011;85:6725-35 pubmed 出版商
Cimini A, Mei S, Benedetti E, Laurenti G, Koutris I, Cinque B, et al. Distinct cellular responses induced by saporin and a transferrin-saporin conjugate in two different human glioblastoma cell lines. J Cell Physiol. 2012;227:939-51 pubmed 出版商
Lo S, Steer J, Joyce D. TNF-α renders macrophages resistant to a range of cancer chemotherapeutic agents through NF-κB-mediated antagonism of apoptosis signalling. Cancer Lett. 2011;307:80-92 pubmed 出版商
Sun Y, Klauzinska M, Lake R, Lee J, Santopietro S, Raafat A, et al. Trp53 regulates Notch 4 signaling through Mdm2. J Cell Sci. 2011;124:1067-76 pubmed 出版商
Tseng C. Prostate cancer mortality in Taiwanese men: increasing age-standardized trend in general population and increased risk in diabetic men. Ann Med. 2011;43:142-50 pubmed 出版商
Perez Alvarez S, Cuenca Lopez M, de Mera R, Puerta E, Karachitos A, Bednarczyk P, et al. Methadone induces necrotic-like cell death in SH-SY5Y cells by an impairment of mitochondrial ATP synthesis. Biochim Biophys Acta. 2010;1802:1036-47 pubmed 出版商
Gomez Sarosi L, Strasberg Rieber M, Rieber M. H(2)O(2) preferentially synergizes with nitroprusside to induce apoptosis associated with superoxide dismutase dysregulation in human melanoma irrespective of p53 status: Antagonism by o-phenanthroline. Chem Biol Interact. 2010;188:134-43 pubmed 出版商
Quintavalle M, Elia L, Condorelli G, Courtneidge S. MicroRNA control of podosome formation in vascular smooth muscle cells in vivo and in vitro. J Cell Biol. 2010;189:13-22 pubmed 出版商
Ichijima Y, Yoshioka K, Yoshioka Y, Shinohe K, Fujimori H, Unno J, et al. DNA lesions induced by replication stress trigger mitotic aberration and tetraploidy development. PLoS ONE. 2010;5:e8821 pubmed 出版商
Moriya J, Minamino T, Tateno K, Okada S, Uemura A, Shimizu I, et al. Inhibition of semaphorin as a novel strategy for therapeutic angiogenesis. Circ Res. 2010;106:391-8 pubmed 出版商
Khan S, Pham S, Wei Y, Mateo D, St Pierre M, Fletcher T, et al. Stress-induced senescence exaggerates postinjury neointimal formation in the old vasculature. Am J Physiol Heart Circ Physiol. 2010;298:H66-74 pubmed 出版商
Wassmann K, Mueller C, Becher U, Werner C, Jung A, Zimmer S, et al. Interaction of Inhibitor of DNA binding 3 (Id3) with Gut-enriched Krüppel-like factor (GKLF) and p53 regulates proliferation of vascular smooth muscle cells. Mol Cell Biochem. 2010;333:33-9 pubmed 出版商
Cha J, Jeong M, Kim H, Lee J, Lee K. MAPK activation is necessary to the apoptotic death of KB cells induced by the essential oil isolated from Artemisia iwayomogi. J Ethnopharmacol. 2009;123:308-14 pubmed 出版商
Cao A, Jin W, Shi P, Di G, Shen Z, Shao Z. Identification and characterization of two novel germ line p53 mutations in the non-LFS/non-LFL breast cancer families in Chinese population. Breast Cancer Res Treat. 2010;119:295-303 pubmed 出版商
Zhuang Z, Fei F, Chen Y, Jin W. Suberoyl bis-hydroxamic acid induces p53-dependent apoptosis of MCF-7 breast cancer cells. Acta Pharmacol Sin. 2008;29:1459-66 pubmed 出版商
Pontes H, Sousa C, Silva R, Fernandes E, Carmo H, Remião F, et al. Synergistic toxicity of ethanol and MDMA towards primary cultured rat hepatocytes. Toxicology. 2008;254:42-50 pubmed 出版商
Semotok J, Luo H, Cooperstock R, Karaiskakis A, Vari H, Smibert C, et al. Drosophila maternal Hsp83 mRNA destabilization is directed by multiple SMAUG recognition elements in the open reading frame. Mol Cell Biol. 2008;28:6757-72 pubmed 出版商
Jia D, Du Z, Liu S, Liu H, Wang F, Ling E, et al. c-Abl is involved in high glucose-induced apoptosis in embryonic E12.5 cortical neural progenitor cells from the mouse brain. J Neurochem. 2008;106:1720-30 pubmed 出版商
Jia D, Liu H, Wang F, Liu S, Ling E, Liu K, et al. Folic acid supplementation affects apoptosis and differentiation of embryonic neural stem cells exposed to high glucose. Neurosci Lett. 2008;440:27-31 pubmed 出版商
Gomez Lazaro M, Galindo M, Concannon C, Segura M, Fernandez Gomez F, Llecha N, et al. 6-Hydroxydopamine activates the mitochondrial apoptosis pathway through p38 MAPK-mediated, p53-independent activation of Bax and PUMA. J Neurochem. 2008;104:1599-612 pubmed
Onoyama I, Tsunematsu R, Matsumoto A, Kimura T, de Alboran I, Nakayama K, et al. Conditional inactivation of Fbxw7 impairs cell-cycle exit during T cell differentiation and results in lymphomatogenesis. J Exp Med. 2007;204:2875-88 pubmed
Ferreira R, Neuparth M, Vitorino R, Appell H, Amado F, Duarte J. Evidences of apoptosis during the early phases of soleus muscle atrophy in hindlimb suspended mice. Physiol Res. 2008;57:601-11 pubmed
Ning X, Chi E, Buroker N, Chen S, Xu C, Tien Y, et al. Moderate hypothermia (30 degrees C) maintains myocardial integrity and modifies response of cell survival proteins after reperfusion. Am J Physiol Heart Circ Physiol. 2007;293:H2119-28 pubmed
Wassmann S, Wassmann K, Jung A, Velten M, Knuefermann P, Petoumenos V, et al. Induction of p53 by GKLF is essential for inhibition of proliferation of vascular smooth muscle cells. J Mol Cell Cardiol. 2007;43:301-7 pubmed
Calaf G, Roy D. Gene expression signature of parathion-transformed human breast epithelial cells. Int J Mol Med. 2007;19:741-50 pubmed
Gomez Lazaro M, Galindo M, Melero Fernandez de Mera R, Fernandez Gomez F, Concannon C, Segura M, et al. Reactive oxygen species and p38 mitogen-activated protein kinase activate Bax to induce mitochondrial cytochrome c release and apoptosis in response to malonate. Mol Pharmacol. 2007;71:736-43 pubmed
Gäreskog M, Cederberg J, Eriksson U, Wentzel P. Maternal diabetes in vivo and high glucose concentration in vitro increases apoptosis in rat embryos. Reprod Toxicol. 2007;23:63-74 pubmed
Son Y, Choi K, Lee J, Kook S, Lee S, Takada K, et al. Involvement of caspase activation and mitochondrial stress in taxol-induced apoptosis of Epstein-Barr virus-infected Akata cells. Biochim Biophys Acta. 2006;1760:1894-902 pubmed
Christman S, Kong B, Landry M, Kim H, Foster D. Contributions of differential p53 expression in the spontaneous immortalization of a chicken embryo fibroblast cell line. BMC Cell Biol. 2006;7:27 pubmed
L ECUYER T, Sanjeev S, Thomas R, Novak R, Das L, Campbell W, et al. DNA damage is an early event in doxorubicin-induced cardiac myocyte death. Am J Physiol Heart Circ Physiol. 2006;291:H1273-80 pubmed
Sdek P, Zhang Z, Cao J, Pan H, Chen W, Zheng J. Alteration of cell-cycle regulatory proteins in human oral epithelial cells immortalized by HPV16 E6 and E7. Int J Oral Maxillofac Surg. 2006;35:653-7 pubmed
Christman S, Kong B, Landry M, Kim H, Foster D. Modulation of p53 expression and its role in the conversion to a fully immortalized chicken embryo fibroblast line. FEBS Lett. 2005;579:6705-15 pubmed
Siu P, Pistilli E, Murlasits Z, Alway S. Hindlimb unloading increases muscle content of cytosolic but not nuclear Id2 and p53 proteins in young adult and aged rats. J Appl Physiol (1985). 2006;100:907-16 pubmed
Ammoun S, Lindholm D, Wootz H, Akerman K, Kukkonen J. G-protein-coupled OX1 orexin/hcrtr-1 hypocretin receptors induce caspase-dependent and -independent cell death through p38 mitogen-/stress-activated protein kinase. J Biol Chem. 2006;281:834-42 pubmed
Gomez Lazaro M, Galindo M, Fernandez Gomez F, Prehn J, Jordan J. Activation of p53 and the pro-apoptotic p53 target gene PUMA during depolarization-induced apoptosis of chromaffin cells. Exp Neurol. 2005;196:96-103 pubmed
Kelley S, Coppola D, Yeatman T, Marcet J. Tumor response to neoadjuvant chemoradiation therapy for rectal adenocarcinoma is mediated by p53-dependent and caspase 8-dependent apoptotic pathways. Clin Colorectal Cancer. 2005;5:114-8 pubmed
Siu P, Alway S. Subcellular responses of p53 and Id2 in fast and slow skeletal muscle in response to stretch-induced overload. J Appl Physiol (1985). 2005;99:1897-904 pubmed
Meng L, Kohlhagen G, Liao Z, Antony S, Sausville E, Pommier Y. DNA-protein cross-links and replication-dependent histone H2AX phosphorylation induced by aminoflavone (NSC 686288), a novel anticancer agent active against human breast cancer cells. Cancer Res. 2005;65:5337-43 pubmed
Schaley J, Polonskaia M, Hearing P. The adenovirus E4-6/7 protein directs nuclear localization of E2F-4 via an arginine-rich motif. J Virol. 2005;79:2301-8 pubmed
Siu P, Alway S. Id2 and p53 participate in apoptosis during unloading-induced muscle atrophy. Am J Physiol Cell Physiol. 2005;288:C1058-73 pubmed
Li Y, Wang L, Li S, Guo T, Guo X, Yan P, et al. p53 protein activates the transcription of human proliferating cell nuclear antigen in response to 4-nitroquinoline N-oxide treatment. Int J Biochem Cell Biol. 2005;37:416-26 pubmed
产品信息
产品名称 :
p53(多克隆抗体240)抗体
基因名称 :
TP53
规格 :
200微克/毫升
价格 :
279美元
目录号 :
sc-99
类型 :
单克隆
宿主 :
小鼠单克隆
抗原 :
p53
反应物种 :
m, r, h
应用 :
免疫印迹, 免疫沉淀
表位 :
156-214(人类)
交货时间 :
在下午三点前下订单在美国的次日送达;从我们美国的办公室通过国际航运两日后送达;在我们的欧洲办事处下订单次日运抵欧洲客户
更多信息或购买 :
公司信息
圣克鲁斯生物技术
上海浦东新区建业路315号2号楼1-6号
asia@scbio.cn
http://www.scbt.com/zh/
800-820-8626
公司总部: 美国
圣克鲁斯生物技术公司拥有最高的质量承诺和客户服务。