产品简要
公司名称 :
Selleck Chemicals
产品类型 :
化学品
产品名称 :
MK-2206 2HCl
目录 :
S1078
规格 :
10 g
价格 :
24, 570.00美元
更多信息或购买 :
文章摘录数: 18
参考文献
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Qian X, Li X, Shi Z, Xia Y, Cai Q, Xu D, et al. PTEN Suppresses Glycolysis by Dephosphorylating and Inhibiting Autophosphorylated PGK1. Mol Cell. 2019;76:516-527.e7 pubmed 出版商
Han R, Hu S, Qin W, Shi J, Hou Q, Wang X, et al. C3a and suPAR drive versican V1 expression in tubular cells of focal segmental glomerulosclerosis. JCI Insight. 2019;4: pubmed 出版商
He J, Deng L, Liu H, Chen T, Chen S, Xia S, et al. BCL2L10/BECN1 modulates hepatoma cells autophagy by regulating PI3K/AKT signaling pathway. Aging (Albany NY). 2019;11:350-370 pubmed 出版商
Du L, Roberts J. Transforming growth factor-β downregulates sGC subunit expression in pulmonary artery smooth muscle cells via MEK and ERK signaling. Am J Physiol Lung Cell Mol Physiol. 2019;316:L20-L34 pubmed 出版商
Bernard S, Myers M, Fang W, Zinda B, Smart C, Lambert D, et al. CXCL1 Derived from Mammary Fibroblasts Promotes Progression of Mammary Lesions to Invasive Carcinoma through CXCR2 Dependent Mechanisms. J Mammary Gland Biol Neoplasia. 2018;23:249-267 pubmed 出版商
Zuzow N, Ghosh A, Leonard M, Liao J, Yang B, Bennett E. Mapping the mammalian ribosome quality control complex interactome using proximity labeling approaches. Mol Biol Cell. 2018;: pubmed 出版商
Brolih S, Parks S, Vial V, Durivault J, Mostosi L, Pouyssegur J, et al. AKT1 restricts the invasive capacity of head and neck carcinoma cells harboring a constitutively active PI3 kinase activity. BMC Cancer. 2018;18:249 pubmed 出版商
Prasasya R, Mayo K. Notch Signaling Regulates Differentiation and Steroidogenesis in Female Mouse Ovarian Granulosa Cells. Endocrinology. 2018;159:184-198 pubmed 出版商
Zhang F, Virshup D, Cheong J. Oncogenic RAS-induced CK1α drives nuclear FOXO proteolysis. Oncogene. 2018;37:363-376 pubmed 出版商
Zhang H, Chen F, He Y, Yi L, Ge C, Shi X, et al. Sensitivity of non-small cell lung cancer to erlotinib is regulated by the Notch/miR-223/FBXW7 pathway. Biosci Rep. 2017;37: pubmed 出版商
Lyu L, Wang B, Xiong C, Zhang X, Zhang X, Zhang J. Selective export of autotaxin from the endoplasmic reticulum. J Biol Chem. 2017;292:7011-7022 pubmed 出版商
Rai R, Hu C, Broton C, Chen Y, Lei M, Chang S. NBS1 Phosphorylation Status Dictates Repair Choice of Dysfunctional Telomeres. Mol Cell. 2017;65:801-817.e4 pubmed 出版商
Lee M, Jeong M, Lee H, Han H, Ko A, Hewitt S, et al. PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis. Nat Commun. 2015;6:7769 pubmed 出版商
Wan N, Liu X, Zhang X, Zhao Y, Hu G, Wan F, et al. Toll-interacting protein contributes to mortality following myocardial infarction through promoting inflammation and apoptosis. Br J Pharmacol. 2015;172:3383-96 pubmed 出版商
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产品信息
目录代码 :
S1078
产品名称 :
MK-2206 2HCl
同义词 :
MK2206 2HCl
靶标 :
Akt
CAS登记号码 :
1032350-13-2, 1032349-93-1 (free base), 1032349-77-1 (HCl)
配方 :
C25H21N5O.2HCl
规格 :
10 g
标价 :
24, 570.00美元
描述 :
MK-2206 is a highly selective inhibitor of Akt1, Akt2 and Akt3 with IC50 of 8, 12 and 65 nM, respectively. Find all the information about MK-2206 dihydrochloride for cell signaling research.
产品类型 :
化学品
更多信息或购买 :
公司信息
Selleck Chemicals
2626 South Loop West, Suite 225
Houston, TX 77054
tech@selleckchem.com?tech@selleck.cn
http://www.selleckchem.com
832-582-8158 86-21-6859 1985 400-668-6834
公司总部: 美国