Schrank B, Aparicio T, Li Y, Chang W, Chait B, Gundersen G, et al. Nuclear ARP2/3 drives DNA break clustering for homology-directed repair. Nature. 2018;559:61-66 pubmed 出版商

Iseka F, Goetz B, Mushtaq I, An W, Cypher L, Bielecki T, et al. Role of the EHD Family of Endocytic Recycling Regulators for TCR Recycling and T Cell Function. J Immunol. 2018;200:483-499 pubmed 出版商

Chen J, Zhong M, Guo H, Davidson D, Mishel S, Lu Y, et al. SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin. Nature. 2017;544:493-497 pubmed 出版商

Fernández Nogales M, Santos Galindo M, Merchán Rubira J, Hoozemans J, Rábano A, Ferrer I, et al. Tau-positive nuclear indentations in P301S tauopathy mice. Brain Pathol. 2017;27:314-322 pubmed 出版商

Devaraju P, Yu J, Eddins D, Mellado Lagarde M, Earls L, Westmoreland J, et al. Haploinsufficiency of the 22q11.2 microdeletion gene Mrpl40 disrupts short-term synaptic plasticity and working memory through dysregulation of mitochondrial calcium. Mol Psychiatry. 2017;22:1313-1326 pubmed 出版商

Fogarty L, Song B, Suppiah Y, Hasan S, Martin H, Hogan S, et al. Bcl-xL dependency coincides with the onset of neurogenesis in the developing mammalian spinal cord. Mol Cell Neurosci. 2016;77:34-46 pubmed 出版商

Chai Y, Sierecki E, Tomatis V, Gormal R, Giles N, Morrow I, et al. Munc18-1 is a molecular chaperone for α-synuclein, controlling its self-replicating aggregation. J Cell Biol. 2016;214:705-18 pubmed 出版商

Sato N, Takasaka N, Yoshida M, Tsubouchi K, Minagawa S, Araya J, et al. Metformin attenuates lung fibrosis development via NOX4 suppression. Respir Res. 2016;17:107 pubmed 出版商

Valencia Gattas M, Conner G, Fregien N. Gefitinib, an EGFR Tyrosine Kinase inhibitor, Prevents Smoke-Mediated Ciliated Airway Epithelial Cell Loss and Promotes Their Recovery. PLoS ONE. 2016;11:e0160216 pubmed 出版商

Nakamichi R, Ito Y, Inui M, Onizuka N, Kayama T, Kataoka K, et al. Mohawk promotes the maintenance and regeneration of the outer annulus fibrosus of intervertebral discs. Nat Commun. 2016;7:12503 pubmed 出版商

Kariya Y, Tatsuta T, Sugawara S, Kariya Y, Nitta K, Hosono M. RNase activity of sialic acid-binding lectin from bullfrog eggs drives antitumor effect via the activation of p38 MAPK to caspase-3/7 signaling pathway in human breast cancer cells. Int J Oncol. 2016;49:1334-42 pubmed 出版商

Busse B, Bezrukov L, Blank P, Zimmerberg J. Resin embedded multicycle imaging (REMI): a tool to evaluate protein domains. Sci Rep. 2016;6:30284 pubmed 出版商

Yuan Y, Wang Y, Liu Q, Zhu F, Hong Y. Singapore grouper iridovirus protein VP088 is essential for viral infectivity. Sci Rep. 2016;6:31170 pubmed 出版商

Kaukonen R, Mai A, Georgiadou M, Saari M, De Franceschi N, Betz T, et al. Normal stroma suppresses cancer cell proliferation via mechanosensitive regulation of JMJD1a-mediated transcription. Nat Commun. 2016;7:12237 pubmed 出版商

Lai M, Gonzalez Martin A, Cooper A, Oda H, Jin H, Shepherd J, et al. Regulation of B-cell development and tolerance by different members of the miR-17∼92 family microRNAs. Nat Commun. 2016;7:12207 pubmed 出版商

Liu X, Ehmed E, Li B, Dou J, Qiao X, Jiang W, et al. Breast cancer metastasis suppressor 1 modulates SIRT1-dependent p53 deacetylation through interacting with DBC1. Am J Cancer Res. 2016;6:1441-9 pubmed

Jang H, Lee G, Selby C, Lee G, Jeon Y, Lee J, et al. SREBP1c-CRY1 signalling represses hepatic glucose production by promoting FOXO1 degradation during refeeding. Nat Commun. 2016;7:12180 pubmed 出版商

Hogg S, Newbold A, Vervoort S, Cluse L, Martin B, Gregory G, et al. BET Inhibition Induces Apoptosis in Aggressive B-Cell Lymphoma via Epigenetic Regulation of BCL-2 Family Members. Mol Cancer Ther. 2016;15:2030-41 pubmed 出版商

Seo H, Lee C, Lee J, Lim S, Choi E, Park J, et al. The role of nuclear factor of activated T cells during phorbol myristate acetate-induced cardiac differentiation of mesenchymal stem cells. Stem Cell Res Ther. 2016;7:90 pubmed 出版商

Kloten V, Schlensog M, Eschenbruch J, Gasthaus J, Tiedemann J, Mijnes J, et al. Abundant NDRG2 Expression Is Associated with Aggressiveness and Unfavorable Patients' Outcome in Basal-Like Breast Cancer. PLoS ONE. 2016;11:e0159073 pubmed 出版商

Xiao L, Feng Q, Zhang Z, Wang F, Lydon J, Ittmann M, et al. The essential role of GATA transcription factors in adult murine prostate. Oncotarget. 2016;7:47891-47903 pubmed 出版商

Gayatri S, Cowles M, Vemulapalli V, Cheng D, Sun Z, Bedford M. Using oriented peptide array libraries to evaluate methylarginine-specific antibodies and arginine methyltransferase substrate motifs. Sci Rep. 2016;6:28718 pubmed 出版商

Timms R, Menzies S, Tchasovnikarova I, Christensen L, Williamson J, Antrobus R, et al. Genetic dissection of mammalian ERAD through comparative haploid and CRISPR forward genetic screens. Nat Commun. 2016;7:11786 pubmed 出版商

Lo Dico A, Costa V, Martelli C, Diceglie C, Rajata F, Rizzo A, et al. MiR675-5p Acts on HIF-1? to Sustain Hypoxic Responses: A New Therapeutic Strategy for Glioma. Theranostics. 2016;6:1105-18 pubmed 出版商

Mukhopadhyay A, Sehgal L, Bose A, Gulvady A, Senapati P, Thorat R, et al. 14-3-3? Prevents Centrosome Amplification and Neoplastic Progression. Sci Rep. 2016;6:26580 pubmed 出版商

Minakawa Y, Atsumi Y, Shinohara A, Murakami Y, Yoshioka K. Gamma-irradiated quiescent cells repair directly induced double-strand breaks but accumulate persistent double-strand breaks during subsequent DNA replication. Genes Cells. 2016;21:789-97 pubmed 出版商

Zeng L, Cai C, Li S, Wang W, Li Y, Chen J, et al. Essential Roles of Cyclin Y-Like 1 and Cyclin Y in Dividing Wnt-Responsive Mammary Stem/Progenitor Cells. PLoS Genet. 2016;12:e1006055 pubmed 出版商

de Jong P, Taniguchi K, Harris A, Bertin S, Takahashi N, Duong J, et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016;7:11551 pubmed 出版商

Benjamin J, Van Der Meer R, Im A, Plosa E, Zaynagetdinov R, Burman A, et al. Epithelial-Derived Inflammation Disrupts Elastin Assembly and Alters Saccular Stage Lung Development. Am J Pathol. 2016;186:1786-1800 pubmed 出版商

Hamam D, Abdouh M, Gao Z, Arena V, Arena M, Arena G. Transfer of malignant trait to BRCA1 deficient human fibroblasts following exposure to serum of cancer patients. J Exp Clin Cancer Res. 2016;35:80 pubmed 出版商

Tenorio M, Ross B, Luchsinger C, Rivera Dictter A, Arriagada C, Acuña D, et al. Distinct Biochemical Pools of Golgi Phosphoprotein 3 in the Human Breast Cancer Cell Lines MCF7 and MDA-MB-231. PLoS ONE. 2016;11:e0154719 pubmed 出版商

Matias A, Manieri T, Cerchiaro G. Zinc Chelation Mediates the Lysosomal Disruption without Intracellular ROS Generation. Oxid Med Cell Longev. 2016;2016:6724585 pubmed 出版商

Scott A, Wilkinson A, Wilkinson J. Basal metabolic state governs AIF-dependent growth support in pancreatic cancer cells. BMC Cancer. 2016;16:286 pubmed 出版商

Leung C, Mak W, Kai A, Chan K, Lee T, Ng I, et al. Sox9 confers stemness properties in hepatocellular carcinoma through Frizzled-7 mediated Wnt/?-catenin signaling. Oncotarget. 2016;7:29371-86 pubmed 出版商

Ren H, Elgner F, Jiang B, Himmelsbach K, Medvedev R, Ploen D, et al. The Autophagosomal SNARE Protein Syntaxin 17 Is an Essential Factor for the Hepatitis C Virus Life Cycle. J Virol. 2016;90:5989-6000 pubmed 出版商

Haemmerle M, Bottsford Miller J, Pradeep S, Taylor M, Choi H, Hansen J, et al. FAK regulates platelet extravasation and tumor growth after antiangiogenic therapy withdrawal. J Clin Invest. 2016;126:1885-96 pubmed 出版商

Katlinskaya Y, Katlinski K, Yu Q, Ortiz A, Beiting D, Brice A, et al. Suppression of Type I Interferon Signaling Overcomes Oncogene-Induced Senescence and Mediates Melanoma Development and Progression. Cell Rep. 2016;15:171-180 pubmed 出版商

Wu S, Rupaimoole R, Shen F, Pradeep S, Pecot C, Ivan C, et al. A miR-192-EGR1-HOXB9 regulatory network controls the angiogenic switch in cancer. Nat Commun. 2016;7:11169 pubmed 出版商

Nemeth T, Futosi K, Sitaru C, Ruland J, Mocsai A. Neutrophil-specific deletion of the CARD9 gene expression regulator suppresses autoantibody-induced inflammation in vivo. Nat Commun. 2016;7:11004 pubmed 出版商

Mosadeghi R, Reichermeier K, Winkler M, Schreiber A, Reitsma J, Zhang Y, et al. Structural and kinetic analysis of the COP9-Signalosome activation and the cullin-RING ubiquitin ligase deneddylation cycle. elife. 2016;5: pubmed 出版商

Iimori M, Watanabe S, Kiyonari S, Matsuoka K, Sakasai R, Saeki H, et al. Phosphorylation of EB2 by Aurora B and CDK1 ensures mitotic progression and genome stability. Nat Commun. 2016;7:11117 pubmed 出版商

Woodfield S, Guo R, Liu Y, Major A, Hollingsworth E, Indiviglio S, et al. Neuroblastoma patient outcomes, tumor differentiation, and ERK activation are correlated with expression levels of the ubiquitin ligase UBE4B. Genes Cancer. 2016;7:13-26 pubmed

Vermeer D, Coppock J, Zeng E, Lee K, Spanos W, Onken M, et al. Metastatic model of HPV+ oropharyngeal squamous cell carcinoma demonstrates heterogeneity in tumor metastasis. Oncotarget. 2016;7:24194-207 pubmed 出版商

Shih Y, Hsueh Y. VCP and ATL1 regulate endoplasmic reticulum and protein synthesis for dendritic spine formation. Nat Commun. 2016;7:11020 pubmed 出版商

Tögel L, Nightingale R, Chueh A, Jayachandran A, Tran H, Phesse T, et al. Dual Targeting of Bromodomain and Extraterminal Domain Proteins, and WNT or MAPK Signaling, Inhibits c-MYC Expression and Proliferation of Colorectal Cancer Cells. Mol Cancer Ther. 2016;15:1217-26 pubmed 出版商

Van De Pette M, Tunster S, McNamara G, Shelkovnikova T, Millership S, Benson L, et al. Cdkn1c Boosts the Development of Brown Adipose Tissue in a Murine Model of Silver Russell Syndrome. PLoS Genet. 2016;12:e1005916 pubmed 出版商

Barja Fernández S, Folgueira C, Castelao C, Al Massadi O, Bravo S, Garcia Caballero T, et al. FNDC5 is produced in the stomach and associated to body composition. Sci Rep. 2016;6:23067 pubmed 出版商

Ma X, Xu L, Mueller E. Forkhead box A3 mediates glucocorticoid receptor function in adipose tissue. Proc Natl Acad Sci U S A. 2016;113:3377-82 pubmed 出版商

Shin J, Nunomiya A, Kitajima Y, Dan T, Miyata T, Nagatomi R. Prolyl hydroxylase domain 2 deficiency promotes skeletal muscle fiber-type transition via a calcineurin/NFATc1-dependent pathway. Skelet Muscle. 2016;6:5 pubmed 出版商

Pokharel D, Padula M, Lu J, Jaiswal R, Djordjevic S, Bebawy M. The Role of CD44 and ERM Proteins in Expression and Functionality of P-glycoprotein in Breast Cancer Cells. Molecules. 2016;21:290 pubmed 出版商

Karuppagounder S, Alim I, Khim S, Bourassa M, Sleiman S, John R, et al. Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Sci Transl Med. 2016;8:328ra29 pubmed 出版商

Cannavo A, Liccardo D, Eguchi A, Elliott K, Traynham C, Ibetti J, et al. Myocardial pathology induced by aldosterone is dependent on non-canonical activities of G protein-coupled receptor kinases. Nat Commun. 2016;7:10877 pubmed 出版商

Woodfield S, Zhang L, Scorsone K, Liu Y, Zage P. Binimetinib inhibits MEK and is effective against neuroblastoma tumor cells with low NF1 expression. BMC Cancer. 2016;16:172 pubmed 出版商

Shin M, He Y, Marrogi E, Piperdi S, Ren L, Khanna C, et al. A RUNX2-Mediated Epigenetic Regulation of the Survival of p53 Defective Cancer Cells. PLoS Genet. 2016;12:e1005884 pubmed 出版商

Weiher H, Pircher H, Jansen Dürr P, Hegenbarth S, Knolle P, Grunau S, et al. A monoclonal antibody raised against bacterially expressed MPV17 sequences shows peroxisomal, endosomal and lysosomal localisation in U2OS cells. BMC Res Notes. 2016;9:128 pubmed 出版商

De Herdt M, Willems S, van der Steen B, Noorlag R, Verhoef E, van Leenders G, et al. Absent and abundant MET immunoreactivity is associated with poor prognosis of patients with oral and oropharyngeal squamous cell carcinoma. Oncotarget. 2016;7:13167-81 pubmed 出版商

Liu L, Liu X, Ren X, Tian Y, Chen Z, Xu X, et al. Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification. Sci Rep. 2016;6:21602 pubmed 出版商

Edalat L, Stegen B, Klumpp L, Haehl E, Schilbach K, Lukowski R, et al. BK K+ channel blockade inhibits radiation-induced migration/brain infiltration of glioblastoma cells. Oncotarget. 2016;7:14259-78 pubmed 出版商

del Río C, Navarrete C, Collado J, Bellido M, Gómez Cañas M, Pazos M, et al. The cannabinoid quinol VCE-004.8 alleviates bleomycin-induced scleroderma and exerts potent antifibrotic effects through peroxisome proliferator-activated receptor-γ and CB2 pathways. Sci Rep. 2016;6:21703 pubmed 出版商

Sparks L, Gemmink A, Phielix E, Bosma M, Schaart G, Moonen Kornips E, et al. ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity. Diabetologia. 2016;59:1030-9 pubmed 出版商

Trivedi P, Bruns T, Ward S, Mai M, Schmidt C, Hirschfield G, et al. Intestinal CCL25 expression is increased in colitis and correlates with inflammatory activity. J Autoimmun. 2016;68:98-104 pubmed 出版商

Xu J, Wang N, Luo J, Xia J. Syntabulin regulates the trafficking of PICK1-containing vesicles in neurons. Sci Rep. 2016;6:20924 pubmed 出版商

Li J, Pan Q, Rowan P, Trotter T, Peker D, Regal K, et al. Heparanase promotes myeloma progression by inducing mesenchymal features and motility of myeloma cells. Oncotarget. 2016;7:11299-309 pubmed 出版商

Zhang J, Jiang Z, Bao C, Mei J, Zhu J. Cardiopulmonary bypass increases pulmonary microvascular permeability through the Src kinase pathway: Involvement of caveolin-1 and vascular endothelial cadherin. Mol Med Rep. 2016;13:2918-24 pubmed 出版商

Heir P, Srikumar T, Bikopoulos G, Bunda S, Poon B, Lee J, et al. Oxygen-dependent Regulation of Erythropoietin Receptor Turnover and Signaling. J Biol Chem. 2016;291:7357-72 pubmed 出版商

Xu C, Ochi H, Fukuda T, Sato S, Sunamura S, Takarada T, et al. Circadian Clock Regulates Bone Resorption in Mice. J Bone Miner Res. 2016;31:1344-55 pubmed 出版商

Jiang P, Gan M, Yen S, Moussaud S, McLean P, Dickson D. Proaggregant nuclear factor(s) trigger rapid formation of ?-synuclein aggregates in apoptotic neurons. Acta Neuropathol. 2016;132:77-91 pubmed 出版商

Duplan E, Giordano C, Checler F, Alves da Costa C. Direct α-synuclein promoter transactivation by the tumor suppressor p53. Mol Neurodegener. 2016;11:13 pubmed 出版商

Hayashi H, Al Mamun A, Sakima M, Sato M. Activator of G-protein signaling 8 is involved in VEGF-mediated signal processing during angiogenesis. J Cell Sci. 2016;129:1210-22 pubmed 出版商

Blanco E, Galeano P, Palomino A, Pavón F, Rivera P, Serrano A, et al. Cocaine-induced behavioral sensitization decreases the expression of endocannabinoid signaling-related proteins in the mouse hippocampus. Eur Neuropsychopharmacol. 2016;26:477-92 pubmed 出版商

Park W, Kim S, Kim Y, Park J. Bortezomib alleviates drug-induced liver injury by regulating CYP2E1 gene transcription. Int J Mol Med. 2016;37:613-22 pubmed 出版商

Soo Lee N, Jin Chung H, Kim H, Yun Lee S, Ji J, Seo Y, et al. TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage. Nat Commun. 2016;7:10463 pubmed 出版商

Wu H, Shi L, Wang Q, Cheng L, Zhao X, Chen Q, et al. Mumps virus-induced innate immune responses in mouse Sertoli and Leydig cells. Sci Rep. 2016;6:19507 pubmed 出版商

Vlčková K, OndruÅ¡ová L, Vachtenheim J, Réda J, Dundr P, Zadinová M, et al. Survivin, a novel target of the Hedgehog/GLI signaling pathway in human tumor cells. Cell Death Dis. 2016;7:e2048 pubmed 出版商

Klawitter S, Fuchs N, Upton K, Muñoz Lopez M, Shukla R, Wang J, et al. Reprogramming triggers endogenous L1 and Alu retrotransposition in human induced pluripotent stem cells. Nat Commun. 2016;7:10286 pubmed 出版商

Monian P, Jiang X. The Cellular Apoptosis Susceptibility Protein (CAS) Promotes Tumor Necrosis Factor-related Apoptosis-inducing Ligand (TRAIL)-induced Apoptosis and Cell Proliferation. J Biol Chem. 2016;291:2379-88 pubmed 出版商

Weijer R, Broekgaarden M, Krekorian M, Alles L, van Wijk A, Mackaaij C, et al. Inhibition of hypoxia inducible factor 1 and topoisomerase with acriflavine sensitizes perihilar cholangiocarcinomas to photodynamic therapy. Oncotarget. 2016;7:3341-56 pubmed 出版商

Hashimoto M, Murata K, Ishida J, Kanou A, Kasuya Y, Fukamizu A. Severe Hypomyelination and Developmental Defects Are Caused in Mice Lacking Protein Arginine Methyltransferase 1 (PRMT1) in the Central Nervous System. J Biol Chem. 2016;291:2237-45 pubmed 出版商

Min J, Guo K, Suryadevara P, Zhu F, Holbrook G, Chen Y, et al. Optimization of a Novel Series of Ataxia-Telangiectasia Mutated Kinase Inhibitors as Potential Radiosensitizing Agents. J Med Chem. 2016;59:559-77 pubmed 出版商

Hagelkruys A, Mattes K, Moos V, Rennmayr M, Ringbauer M, Sawicka A, et al. Essential Nonredundant Function of the Catalytic Activity of Histone Deacetylase 2 in Mouse Development. Mol Cell Biol. 2016;36:462-74 pubmed 出版商

Kim M, Kim M, Park S, Lee C, Lim D. Role of Angiomotin-like 2 mono-ubiquitination on YAP inhibition. EMBO Rep. 2016;17:64-78 pubmed 出版商

Wang C, Wang Y, Hu M, Chai Z, Wu Q, Huang R, et al. Synaptotagmin-11 inhibits clathrin-mediated and bulk endocytosis. EMBO Rep. 2016;17:47-63 pubmed 出版商

Elgner F, Donnerhak C, Ren H, Medvedev R, Schreiber A, Weber L, et al. Characterization of α-taxilin as a novel factor controlling the release of hepatitis C virus. Biochem J. 2016;473:145-55 pubmed 出版商

Qiao Y, Lin S, Chen Y, Voon D, Zhu F, Chuang L, et al. RUNX3 is a novel negative regulator of oncogenic TEAD-YAP complex in gastric cancer. Oncogene. 2016;35:2664-74 pubmed 出版商

Ronchi G, Haastert Talini K, Fornasari B, Perroteau I, Geuna S, Gambarotta G. The Neuregulin1/ErbB system is selectively regulated during peripheral nerve degeneration and regeneration. Eur J Neurosci. 2016;43:351-64 pubmed 出版商

Park S, Shim J, Park H, Eum D, Park M, Mi Yi J, et al. MacroH2A1 downregulation enhances the stem-like properties of bladder cancer cells by transactivation of Lin28B. Oncogene. 2016;35:1292-301 pubmed 出版商

Garcia P, Miller A, Kreitzburg K, Council L, Gamblin T, Christein J, et al. The BET bromodomain inhibitor JQ1 suppresses growth of pancreatic ductal adenocarcinoma in patient-derived xenograft models. Oncogene. 2016;35:833-45 pubmed 出版商

Ding X, Jiang W, Zhou P, Liu L, Wan X, Yuan X, et al. Mixed Lineage Leukemia 5 (MLL5) Protein Stability Is Cooperatively Regulated by O-GlcNac Transferase (OGT) and Ubiquitin Specific Protease 7 (USP7). PLoS ONE. 2015;10:e0145023 pubmed 出版商

Adam M, Matt S, Christian S, Hess Stumpp H, Haegebarth A, Hofmann T, et al. SIAH ubiquitin ligases regulate breast cancer cell migration and invasion independent of the oxygen status. Cell Cycle. 2015;14:3734-47 pubmed 出版商

Iskit S, Schlicker A, Wessels L, Peeper D. Fra-1 is a key driver of colon cancer metastasis and a Fra-1 classifier predicts disease-free survival. Oncotarget. 2015;6:43146-61 pubmed 出版商

Bunda S, Burrell K, Heir P, Zeng L, Alamsahebpour A, Kano Y, et al. Inhibition of SHP2-mediated dephosphorylation of Ras suppresses oncogenesis. Nat Commun. 2015;6:8859 pubmed 出版商

Gao L, Jiang Y, Mu L, Liu Y, Wang F, Wang P, et al. Efficient Generation of Mice with Consistent Transgene Expression by FEEST. Sci Rep. 2015;5:16284 pubmed 出版商

Amigo Jiménez I, Bailón E, Aguilera Montilla N, Terol M, García Marco J, García Pardo A. Bone marrow stroma-induced resistance of chronic lymphocytic leukemia cells to arsenic trioxide involves Mcl-1 upregulation and is overcome by inhibiting the PI3Kδ or PKCβ signaling pathways. Oncotarget. 2015;6:44832-48 pubmed 出版商

Shi J, Fung G, Deng H, Zhang J, Fiesel F, Springer W, et al. NBR1 is dispensable for PARK2-mediated mitophagy regardless of the presence or absence of SQSTM1. Cell Death Dis. 2015;6:e1943 pubmed 出版商

Heishima K, Mori T, Ichikawa Y, Sakai H, Kuranaga Y, Nakagawa T, et al. MicroRNA-214 and MicroRNA-126 Are Potential Biomarkers for Malignant Endothelial Proliferative Diseases. Int J Mol Sci. 2015;16:25377-91 pubmed 出版商

Gökbuget D, Pereira J, Bachofner S, Marchais A, Ciaudo C, Stoffel M, et al. The Lin28/let-7 axis is critical for myelination in the peripheral nervous system. Nat Commun. 2015;6:8584 pubmed 出版商

Kabaria S, Choi D, Chaudhuri A, Jain M, Li H, Junn E. MicroRNA-7 activates Nrf2 pathway by targeting Keap1 expression. Free Radic Biol Med. 2015;89:548-56 pubmed 出版商

Yu D, Makkar G, Strickland D, Blanpied T, Stumpo D, Blackshear P, et al. Myristoylated Alanine-Rich Protein Kinase Substrate (MARCKS) Regulates Small GTPase Rac1 and Cdc42 Activity and Is a Critical Mediator of Vascular Smooth Muscle Cell Migration in Intimal Hyperplasia Formation. J Am Heart Assoc. 2015;4:e002255 pubmed 出版商

André P, Prêle C, Vierkotten S, Carnesecchi S, Donati Y, Chambers R, et al. BARD1 mediates TGF-β signaling in pulmonary fibrosis. Respir Res. 2015;16:118 pubmed 出版商

Pellet Many C, Mehta V, Fields L, Mahmoud M, Lowe V, Evans I, et al. Neuropilins 1 and 2 mediate neointimal hyperplasia and re-endothelialization following arterial injury. Cardiovasc Res. 2015;108:288-98 pubmed 出版商

Mazur P, Herner A, Mello S, Wirth M, Hausmann S, Sánchez Rivera F, et al. Combined inhibition of BET family proteins and histone deacetylases as a potential epigenetics-based therapy for pancreatic ductal adenocarcinoma. Nat Med. 2015;21:1163-71 pubmed 出版商

Nemazanyy I, Montagnac G, Russell R, Morzyglod L, Burnol A, Guan K, et al. Class III PI3K regulates organismal glucose homeostasis by providing negative feedback on hepatic insulin signalling. Nat Commun. 2015;6:8283 pubmed 出版商

Yang L, McKnight G. Hypothalamic PKA regulates leptin sensitivity and adiposity. Nat Commun. 2015;6:8237 pubmed 出版商

Zoppi N, Chiarelli N, Cinquina V, Ritelli M, Colombi M. GLUT10 deficiency leads to oxidative stress and non-canonical αvβ3 integrin-mediated TGFβ signalling associated with extracellular matrix disarray in arterial tortuosity syndrome skin fibroblasts. Hum Mol Genet. 2015;24:6769-87 pubmed 出版商

Laird J, Pan Y, Modestou M, Yamaguchi D, Song H, Sokolov M, et al. Identification of a VxP Targeting Signal in the Flagellar Na+ /K+ -ATPase. Traffic. 2015;16:1239-53 pubmed 出版商

Li M, Yang S, Xing B, Ferguson B, Gulchina Y, Li Y, et al. LY395756, an mGluR2 agonist and mGluR3 antagonist, enhances NMDA receptor expression and function in the normal adult rat prefrontal cortex, but fails to improve working memory and reverse MK801-induced working memory impairment. Exp Neurol. 2015;273:190-201 pubmed 出版商

Heishima K, Mori T, Sakai H, Sugito N, Murakami M, Yamada N, et al. MicroRNA-214 Promotes Apoptosis in Canine Hemangiosarcoma by Targeting the COP1-p53 Axis. PLoS ONE. 2015;10:e0137361 pubmed 出版商

Pflibsen L, Stang K, Sconce M, Wilson V, Hood R, Meshul C, et al. Executive function deficits and glutamatergic protein alterations in a progressive 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine mouse model of Parkinson's disease. J Neurosci Res. 2015;93:1849-64 pubmed 出版商

Wu X, Zahari M, Renuse S, Nirujogi R, Kim M, Manda S, et al. Phosphoproteomic Analysis Identifies Focal Adhesion Kinase 2 (FAK2) as a Potential Therapeutic Target for Tamoxifen Resistance in Breast Cancer. Mol Cell Proteomics. 2015;14:2887-900 pubmed 出版商

Tiffen J, Gunatilake D, Gallagher S, Gowrishankar K, Heinemann A, Cullinane C, et al. Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes. Oncotarget. 2015;6:27023-36 pubmed 出版商

Kauko O, Laajala T, Jumppanen M, Hintsanen P, Suni V, Haapaniemi P, et al. Label-free quantitative phosphoproteomics with novel pairwise abundance normalization reveals synergistic RAS and CIP2A signaling. Sci Rep. 2015;5:13099 pubmed 出版商

Kieffer Kwon P, Happel C, Uldrick T, Ramalingam D, Ziegelbauer J. KSHV MicroRNAs Repress Tropomyosin 1 and Increase Anchorage-Independent Growth and Endothelial Tube Formation. PLoS ONE. 2015;10:e0135560 pubmed 出版商

Swindell W, Remmer H, Sarkar M, Xing X, Barnes D, Wolterink L, et al. Proteogenomic analysis of psoriasis reveals discordant and concordant changes in mRNA and protein abundance. Genome Med. 2015;7:86 pubmed 出版商

Roggia M, Ueta T. αvβ5 Integrin/FAK/PGC-1α Pathway Confers Protective Effects on Retinal Pigment Epithelium. PLoS ONE. 2015;10:e0134870 pubmed 出版商

Hieke N, Löffler A, Kaizuka T, Berleth N, Böhler P, Drießen S, et al. Expression of a ULK1/2 binding-deficient ATG13 variant can partially restore autophagic activity in ATG13-deficient cells. Autophagy. 2015;11:1471-83 pubmed 出版商

Kiyonari S, Iimori M, Matsuoka K, Watanabe S, Morikawa Ichinose T, Miura D, et al. The 1,2-Diaminocyclohexane Carrier Ligand in Oxaliplatin Induces p53-Dependent Transcriptional Repression of Factors Involved in Thymidylate Biosynthesis. Mol Cancer Ther. 2015;14:2332-42 pubmed 出版商

Drießen S, Berleth N, Friesen O, Löffler A, Böhler P, Hieke N, et al. Deubiquitinase inhibition by WP1130 leads to ULK1 aggregation and blockade of autophagy. Autophagy. 2015;11:1458-70 pubmed 出版商

Lee M, Jeong M, Lee H, Han H, Ko A, Hewitt S, et al. PI3K/AKT activation induces PTEN ubiquitination and destabilization accelerating tumourigenesis. Nat Commun. 2015;6:7769 pubmed 出版商

Quintana P, Soto D, Poirot O, Zonouzi M, Kellenberger S, Muller D, et al. Acid-sensing ion channel 1a drives AMPA receptor plasticity following ischaemia and acidosis in hippocampal CA1 neurons. J Physiol. 2015;593:4373-86 pubmed 出版商

Kontro H, Cannino G, Rustin P, Dufour E, Kainulainen H. DAPIT Over-Expression Modulates Glucose Metabolism and Cell Behaviour in HEK293T Cells. PLoS ONE. 2015;10:e0131990 pubmed 出版商

Wu C, Jiao H, Lai Y, Zheng W, Chen K, Qu H, et al. Kindlin-2 controls TGF-β signalling and Sox9 expression to regulate chondrogenesis. Nat Commun. 2015;6:7531 pubmed 出版商

Kim A, Park Y, Pan X, Shin K, Kwak S, Bassas A, et al. Obesity-induced DNA hypermethylation of the adiponectin gene mediates insulin resistance. Nat Commun. 2015;6:7585 pubmed 出版商

Jacquin S, Rincheval V, Mignotte B, Richard S, Humbert M, Mercier O, et al. Inactivation of p53 Is Sufficient to Induce Development of Pulmonary Hypertension in Rats. PLoS ONE. 2015;10:e0131940 pubmed 出版商

Chhabra S, Jain S, Wallace C, Hong F, Liu B. High expression of endoplasmic reticulum chaperone grp94 is a novel molecular hallmark of malignant plasma cells in multiple myeloma. J Hematol Oncol. 2015;8:77 pubmed 出版商

Gopinathan G, Milagre C, Pearce O, Reynolds L, Hodivala Dilke K, Leinster D, et al. Interleukin-6 Stimulates Defective Angiogenesis. Cancer Res. 2015;75:3098-107 pubmed 出版商

Kim J, Jeong M, Lee S, Song J. Camptothecin and topotecan inhibit adipocyte differentiation by inducing degradation of PPARγ. Biochem Biophys Res Commun. 2015;463:1122-8 pubmed 出版商

de Wilde A, Wannee K, Scholte F, Goeman J, Ten Dijke P, Snijder E, et al. A Kinome-Wide Small Interfering RNA Screen Identifies Proviral and Antiviral Host Factors in Severe Acute Respiratory Syndrome Coronavirus Replication, Including Double-Stranded RNA-Activated Protein Kinase and Early Secretory Pathway Proteins. J Virol. 2015;89:8318-33 pubmed 出版商

Barber A, Castillo Martin M, Bonal D, Jia A, Rybicki B, Christiano A, et al. PI3K/AKT pathway regulates E-cadherin and Desmoglein 2 in aggressive prostate cancer. Cancer Med. 2015;4:1258-71 pubmed 出版商

Bosco D, Kenworthy R, Zorio D, Sang Q. Human mesenchymal stem cells are resistant to Paclitaxel by adopting a non-proliferative fibroblastic state. PLoS ONE. 2015;10:e0128511 pubmed 出版商

Musicki B, Zhang Y, Chen H, Brown T, Zirkin B, Burnett A. Mechanism of testosterone deficiency in the transgenic sickle cell mouse. PLoS ONE. 2015;10:e0128694 pubmed 出版商

Yu J, Ramasamy T, Murphy N, Holt M, Czapiewski R, Wei S, et al. PI3K/mTORC2 regulates TGF-β/Activin signalling by modulating Smad2/3 activity via linker phosphorylation. Nat Commun. 2015;6:7212 pubmed 出版商

Watanabe S, Sanuki R, Sugita Y, Imai W, Yamazaki R, Kozuka T, et al. Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity. J Neurosci. 2015;35:8004-20 pubmed 出版商

Yang C, Chiang C, Chen C, Lee Y, Wu M, Tsou Y, et al. Identification and characterization of nuclear and nucleolar localization signals in 58-kDa microspherule protein (MSP58). J Biomed Sci. 2015;22:33 pubmed 出版商

Wong T, Lin S, Leung L. The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68. Br J Nutr. 2015;113:1844-52 pubmed 出版商

Lin A, Beasley F, Olson J, Keller N, Shalwitz R, Hannan T, et al. Role of Hypoxia Inducible Factor-1α (HIF-1α) in Innate Defense against Uropathogenic Escherichia coli Infection. PLoS Pathog. 2015;11:e1004818 pubmed 出版商

Studzian M, Bartosz G, Pulaski L. Endocytosis of ABCG2 drug transporter caused by binding of 5D3 antibody: trafficking mechanisms and intracellular fate. Biochim Biophys Acta. 2015;1853:1759-71 pubmed 出版商

Suzuki M, Takeda T, Nakagawa H, Iwata S, Watanabe T, Siddiquey M, et al. The heat shock protein 90 inhibitor BIIB021 suppresses the growth of T and natural killer cell lymphomas. Front Microbiol. 2015;6:280 pubmed 出版商

Sheean R, Weston R, Perera N, D Amico A, Nutt S, Turner B. Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice. J Neuroinflammation. 2015;12:40 pubmed 出版商

Uetake Y, Ikeda H, Irie R, Tejima K, Matsui H, Ogura S, et al. High-salt in addition to high-fat diet may enhance inflammation and fibrosis in liver steatosis induced by oxidative stress and dyslipidemia in mice. Lipids Health Dis. 2015;14:6 pubmed 出版商

Vishwamitra D, Curry C, Alkan S, Song Y, Gallick G, Kaseb A, et al. The transcription factors Ik-1 and MZF1 downregulate IGF-IR expression in NPM-ALK⁺ T-cell lymphoma. Mol Cancer. 2015;14:53 pubmed 出版商

Basu S, Thorat R, Dalal S. MMP7 is required to mediate cell invasion and tumor formation upon Plakophilin3 loss. PLoS ONE. 2015;10:e0123979 pubmed 出版商

Jühlen R, Idkowiak J, Taylor A, Kind B, Arlt W, Huebner A, et al. Role of ALADIN in human adrenocortical cells for oxidative stress response and steroidogenesis. PLoS ONE. 2015;10:e0124582 pubmed 出版商

Kropp K, Hsieh W, Isern E, Forster T, Krause E, Brune W, et al. A temporal gate for viral enhancers to co-opt Toll-like-receptor transcriptional activation pathways upon acute infection. PLoS Pathog. 2015;11:e1004737 pubmed 出版商

Vashist S, Ureña L, Gonzalez Hernandez M, Choi J, de Rougemont A, Rocha Pereira J, et al. Molecular chaperone Hsp90 is a therapeutic target for noroviruses. J Virol. 2015;89:6352-63 pubmed 出版商

Schilling D, Kühnel A, Tetzlaff F, Konrad S, Multhoff G. NZ28-induced inhibition of HSF1, SP1 and NF-κB triggers the loss of the natural killer cell-activating ligands MICA/B on human tumor cells. Cancer Immunol Immunother. 2015;64:599-608 pubmed 出版商

Hausmann S, Brandt E, Köchel C, Einsele H, Bargou R, Seggewiss Bernhardt R, et al. Loss of serum and glucocorticoid-regulated kinase 3 (SGK3) does not affect proliferation and survival of multiple myeloma cell lines. PLoS ONE. 2015;10:e0122689 pubmed 出版商

Neira Peña T, Rojas Mancilla E, Munoz Vio V, Perez R, Gutierrez Hernandez M, Bustamante D, et al. Perinatal asphyxia leads to PARP-1 overactivity, p65 translocation, IL-1β and TNF-α overexpression, and apoptotic-like cell death in mesencephalon of neonatal rats: prevention by systemic neonatal nicotinamide administration. Neurotox Res. 2015;27:453-65 pubmed 出版商

Yamakoshi K, Katano S, Iida M, Kimura H, Okuma A, Ikemoto Uezumi M, et al. Dysregulation of the Bmi-1/p16(Ink⁴a) pathway provokes an aging-associated decline of submandibular gland function. Aging Cell. 2015;14:616-24 pubmed 出版商

Yun H, Xie J, Olumi A, Ghosh R, Kumar A. Activation of AKR1C1/ERβ induces apoptosis by downregulation of c-FLIP in prostate cancer cells: A prospective therapeutic opportunity. Oncotarget. 2015;6:11600-13 pubmed

Hsieh C, Botta G, Gao S, Li T, Van Allen E, Treacy D, et al. PLZF, a tumor suppressor genetically lost in metastatic castration-resistant prostate cancer, is a mediator of resistance to androgen deprivation therapy. Cancer Res. 2015;75:1944-8 pubmed 出版商

Chu V, Weber T, Wefers B, Wurst W, Sander S, Rajewsky K, et al. Increasing the efficiency of homology-directed repair for CRISPR-Cas9-induced precise gene editing in mammalian cells. Nat Biotechnol. 2015;33:543-8 pubmed 出版商

Venkatesh A, Ma S, Le Y, Hall M, Rüegg M, Punzo C. Activated mTORC1 promotes long-term cone survival in retinitis pigmentosa mice. J Clin Invest. 2015;125:1446-58 pubmed 出版商

Shibayama Y, Kondo T, Ohya H, Fujisawa S, Teshima T, Iseki K. Upregulation of microRNA-126-5p is associated with drug resistance to cytarabine and poor prognosis in AML patients. Oncol Rep. 2015;33:2176-82 pubmed 出版商

López González I, Schlüter A, Aso E, Garcia Esparcia P, Ansoleaga B, Llorens F, et al. Neuroinflammatory signals in Alzheimer disease and APP/PS1 transgenic mice: correlations with plaques, tangles, and oligomeric species. J Neuropathol Exp Neurol. 2015;74:319-44 pubmed 出版商

Warren D, Tajsic T, Porter L, Minaisah R, Cobb A, Jacob A, et al. Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing. Cell Death Differ. 2015;22:1540-50 pubmed 出版商

Aubrey B, Kelly G, Kueh A, Brennan M, O Connor L, Milla L, et al. An inducible lentiviral guide RNA platform enables the identification of tumor-essential genes and tumor-promoting mutations in vivo. Cell Rep. 2015;10:1422-32 pubmed 出版商

Prabhu A, Sarcar B, Miller C, Kim S, Nakano I, Forsyth P, et al. Ras-mediated modulation of pyruvate dehydrogenase activity regulates mitochondrial reserve capacity and contributes to glioblastoma tumorigenesis. Neuro Oncol. 2015;17:1220-30 pubmed 出版商

Mourier A, Motori E, Brandt T, Lagouge M, Atanassov I, Galinier A, et al. Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels. J Cell Biol. 2015;208:429-42 pubmed 出版商

Guillaumond F, Bidaut G, Ouaissi M, Servais S, Gouirand V, Olivares O, et al. Cholesterol uptake disruption, in association with chemotherapy, is a promising combined metabolic therapy for pancreatic adenocarcinoma. Proc Natl Acad Sci U S A. 2015;112:2473-8 pubmed 出版商

Michelet X, Garg S, Wolf B, Tuli A, Ricciardi Castagnoli P, Brenner M. MHC class II presentation is controlled by the lysosomal small GTPase, Arl8b. J Immunol. 2015;194:2079-88 pubmed 出版商

La Sala G, Marazziti D, Di Pietro C, Golini E, Matteoni R, Tocchini Valentini G. Modulation of Dhh signaling and altered Sertoli cell function in mice lacking the GPR37-prosaposin receptor. FASEB J. 2015;29:2059-69 pubmed 出版商

Lu W, Liu S, Li B, Xie Y, Adhiambo C, Yang Q, et al. SKP2 inactivation suppresses prostate tumorigenesis by mediating JARID1B ubiquitination. Oncotarget. 2015;6:771-88 pubmed

Wang W, Visavadiya N, Pandya J, Nelson P, Sullivan P, Springer J. Mitochondria-associated microRNAs in rat hippocampus following traumatic brain injury. Exp Neurol. 2015;265:84-93 pubmed 出版商

Jepsen M, Kløverpris S, Mikkelsen J, Pedersen J, Füchtbauer E, Laursen L, et al. Stanniocalcin-2 inhibits mammalian growth by proteolytic inhibition of the insulin-like growth factor axis. J Biol Chem. 2015;290:3430-9 pubmed 出版商

Han Y, Hsieh F. Osteogenic differentiation of late-outgrowth CD45-negative endothelial progenitor cells. J Vasc Res. 2014;51:369-75 pubmed 出版商

Zhang D, Wang X, Li Y, Zhao L, Lu M, Yao X, et al. Thyroid hormone regulates muscle fiber type conversion via miR-133a1. J Cell Biol. 2014;207:753-66 pubmed 出版商

Winkler M, Dib C, Ljubimov A, Saghizadeh M. Targeting miR-146a to treat delayed wound healing in human diabetic organ-cultured corneas. PLoS ONE. 2014;9:e114692 pubmed 出版商

Ventelä S, Sittig E, Mannermaa L, Mäkelä J, Kulmala J, Löyttyniemi E, et al. CIP2A is an Oct4 target gene involved in head and neck squamous cell cancer oncogenicity and radioresistance. Oncotarget. 2015;6:144-58 pubmed

Lu S, Zeumer L, Sorensen H, Yang H, Ng Y, Yu F, et al. The murine Pbx1-d lupus susceptibility allele accelerates mesenchymal stem cell differentiation and impairs their immunosuppressive function. J Immunol. 2015;194:43-55 pubmed

Nashine S, Liu Y, Kim B, Clark A, Pang I. Role of C/EBP homologous protein in retinal ganglion cell death after ischemia/reperfusion injury. Invest Ophthalmol Vis Sci. 2014;56:221-31 pubmed 出版商

Kim H, Xu H, Yao Q, Li W, Huang Q, Outeda P, et al. Ciliary membrane proteins traffic through the Golgi via a Rabep1/GGA1/Arl3-dependent mechanism. Nat Commun. 2014;5:5482 pubmed 出版商

Gascon E, Lynch K, Ruan H, Almeida S, Verheyden J, Seeley W, et al. Alterations in microRNA-124 and AMPA receptors contribute to social behavioral deficits in frontotemporal dementia. Nat Med. 2014;20:1444-51 pubmed 出版商

Marques Howarth M, Simpson D, Ngok S, Nieves B, Chen R, Siprashvili Z, et al. Long noncoding RNA EWSAT1-mediated gene repression facilitates Ewing sarcoma oncogenesis. J Clin Invest. 2014;124:5275-90 pubmed 出版商

Plosa E, Young L, Gulleman P, Polosukhin V, Zaynagetdinov R, Benjamin J, et al. Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization. Development. 2014;141:4751-62 pubmed 出版商

Kim M, Kim M, Lee M, Kim C, Lim D. The MST1/2-SAV1 complex of the Hippo pathway promotes ciliogenesis. Nat Commun. 2014;5:5370 pubmed 出版商

Wang D, Zhang P, Gao K, Tang Y, Jin X, Zhang Y, et al. PLK1 and β-TrCP-dependent ubiquitination and degradation of Rap1GAP controls cell proliferation. PLoS ONE. 2014;9:e110296 pubmed 出版商

Bailey Elkin B, Knaap R, Johnson G, Dalebout T, Ninaber D, van Kasteren P, et al. Crystal structure of the Middle East respiratory syndrome coronavirus (MERS-CoV) papain-like protease bound to ubiquitin facilitates targeted disruption of deubiquitinating activity to demonstrate its role in innate immune suppression. J Biol Chem. 2014;289:34667-82 pubmed 出版商

Zhang Y, Wang N, Su P, Lu J, Wang Y. Disruption of dopamine D1 receptor phosphorylation at serine 421 attenuates cocaine-induced behaviors in mice. Neurosci Bull. 2014;30:1025-35 pubmed 出版商

Kinjo E, Higa G, Morya E, Valle A, Kihara A, Britto L. Reciprocal regulation of epileptiform neuronal oscillations and electrical synapses in the rat hippocampus. PLoS ONE. 2014;9:e109149 pubmed 出版商

Lee S, Xu G, Jay T, Bhatta S, Kim K, Jung S, et al. Opposing effects of membrane-anchored CX3CL1 on amyloid and tau pathologies via the p38 MAPK pathway. J Neurosci. 2014;34:12538-46 pubmed 出版商

Jung K, Han D, Jeong S, Choi M, Chai Y, Cho G. Proteomic analysis reveals KRIT1 as a modulator for the antioxidant effects of valproic acid in human bone-marrow mesenchymal stromal cells. Drug Chem Toxicol. 2015;38:286-92 pubmed 出版商

Abazyan S, Yang E, Abazyan B, Xia M, Yang C, Rojas C, et al. Mutant disrupted-in-schizophrenia 1 in astrocytes: focus on glutamate metabolism. J Neurosci Res. 2014;92:1659-68 pubmed 出版商

Steiner E, Enzmann G, Lyck R, Lin S, Ruegg M, Kroger S, et al. The heparan sulfate proteoglycan agrin contributes to barrier properties of mouse brain endothelial cells by stabilizing adherens junctions. Cell Tissue Res. 2014;358:465-79 pubmed 出版商

Sutiwisesak R, Kitiyanant N, Kotchabhakdi N, Felsenfeld G, Andrews P, Wongtrakoongate P. Induced pluripotency enables differentiation of human nullipotent embryonal carcinoma cells N2102Ep. Biochim Biophys Acta. 2014;1843:2611-9 pubmed 出版商

Saha S, Parachoniak C, Ghanta K, Fitamant J, Ross K, Najem M, et al. Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer. Nature. 2014;513:110-4 pubmed 出版商

Ouyang H, Xue Y, Lin Y, Zhang X, Xi L, Patel S, et al. WNT7A and PAX6 define corneal epithelium homeostasis and pathogenesis. Nature. 2014;511:358-61 pubmed 出版商

Kehoe L, Bellone C, De Roo M, Zandueta A, Dey P, Pérez Otaño I, et al. GluN3A promotes dendritic spine pruning and destabilization during postnatal development. J Neurosci. 2014;34:9213-21 pubmed 出版商

Zhang P, Gao K, Tang Y, Jin X, An J, Yu H, et al. Destruction of DDIT3/CHOP protein by wild-type SPOP but not prostate cancer-associated mutants. Hum Mutat. 2014;35:1142-51 pubmed 出版商

Kopaliani I, Martin M, Zatschler B, Bortlik K, Müller B, Deussen A. Cell-specific and endothelium-dependent regulations of matrix metalloproteinase-2 in rat aorta. Basic Res Cardiol. 2014;109:419 pubmed 出版商

Lakshminarayan R, Wunder C, Becken U, Howes M, Benzing C, Arumugam S, et al. Galectin-3 drives glycosphingolipid-dependent biogenesis of clathrin-independent carriers. Nat Cell Biol. 2014;16:595-606 pubmed 出版商

Durak O, de Anda F, Singh K, Leussis M, Petryshen T, Sklar P, et al. Ankyrin-G regulates neurogenesis and Wnt signaling by altering the subcellular localization of ?-catenin. Mol Psychiatry. 2015;20:388-97 pubmed 出版商

Thoresen S, Campsteijn C, Vietri M, Schink K, Liestøl K, Andersen J, et al. ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4. Nat Cell Biol. 2014;16:550-60 pubmed 出版商

Dichamp I, Seite P, Agius G, Barbarin A, Beby Defaux A. Human papillomavirus 16 oncoprotein E7 stimulates UBF1-mediated rDNA gene transcription, inhibiting a p53-independent activity of p14ARF. PLoS ONE. 2014;9:e96136 pubmed 出版商

Tossetta G, Paolinelli F, Avellini C, Salvolini E, Ciarmela P, Lorenzi T, et al. IL-1? and TGF-? weaken the placental barrier through destruction of tight junctions: an in vivo and in vitro study. Placenta. 2014;35:509-16 pubmed 出版商

Gürtler C, Carty M, Kearney J, Schattgen S, Ding A, Fitzgerald K, et al. SARM regulates CCL5 production in macrophages by promoting the recruitment of transcription factors and RNA polymerase II to the Ccl5 promoter. J Immunol. 2014;192:4821-32 pubmed 出版商

Wojdyla L, Stone A, Sethakorn N, Uppada S, Devito J, Bissonnette M, et al. T-oligo as an anticancer agent in colorectal cancer. Biochem Biophys Res Commun. 2014;446:596-601 pubmed 出版商

Kennedy E, Hakimjavadi R, Greene C, Mooney C, Fitzpatrick E, Collins L, et al. Embryonic rat vascular smooth muscle cells revisited - a model for neonatal, neointimal SMC or differentiated vascular stem cells?. Vasc Cell. 2014;6:6 pubmed 出版商

Termini C, Cotter M, Marjon K, Buranda T, Lidke K, Gillette J. The membrane scaffold CD82 regulates cell adhesion by altering α4 integrin stability and molecular density. Mol Biol Cell. 2014;25:1560-73 pubmed 出版商

Durmus S, Naik J, Buil L, Wagenaar E, van Tellingen O, Schinkel A. In vivo disposition of doxorubicin is affected by mouse Oatp1a/1b and human OATP1A/1B transporters. Int J Cancer. 2014;135:1700-10 pubmed 出版商

Pournara A, Holmlund T, Lu Y, Ceder R, Putnik M, Grafstrom R, et al. Arsenic-induced suppression of kidney cell proliferation and the transcriptional coregulator MAML1. Metallomics. 2014;6:498-504 pubmed 出版商

Low Calle A, Prada Arismendy J, Castellanos J. Study of interferon-? antiviral activity against Herpes simplex virus type 1 in neuron-enriched trigeminal ganglia cultures. Virus Res. 2014;180:49-58 pubmed 出版商

Gregoraszczuk E, Ptak A, Karpeta A, Fiedor E, Wrobel A, Milewicz T, et al. Hexachlorobenzene and pentachlorobenzene accumulation, metabolism and effect on steroid secretion and on CYP11A1 and CYP19 expression in cultured human placental tissue. Reprod Toxicol. 2014;43:102-10 pubmed 出版商

Wang N, Su P, Zhang Y, Lu J, Xing B, Kang K, et al. Protein kinase D1-dependent phosphorylation of dopamine D1 receptor regulates cocaine-induced behavioral responses. Neuropsychopharmacology. 2014;39:1290-301 pubmed 出版商

Liu F, Wang X, Hu G, Wang Y, Zhou J. The transcription factor TEAD1 represses smooth muscle-specific gene expression by abolishing myocardin function. J Biol Chem. 2014;289:3308-16 pubmed 出版商

Andresen C, Smedegaard S, Sylvestersen K, Svensson C, Iglesias Gato D, Cazzamali G, et al. Protein interaction screening for the ankyrin repeats and suppressor of cytokine signaling (SOCS) box (ASB) family identify Asb11 as a novel endoplasmic reticulum resident ubiquitin ligase. J Biol Chem. 2014;289:2043-54 pubmed 出版商

Wongtrakoongate P, Li J, Andrews P. DNMT3B inhibits the re-expression of genes associated with induced pluripotency. Exp Cell Res. 2014;321:231-9 pubmed 出版商

Morotti A, Panuzzo C, Crivellaro S, Pergolizzi B, Familiari U, Berger A, et al. BCR-ABL disrupts PTEN nuclear-cytoplasmic shuttling through phosphorylation-dependent activation of HAUSP. Leukemia. 2014;28:1326-33 pubmed 出版商

Ngamsiri P, Watcharasit P, Satayavivad J. Glycogen synthase kinase-3 (GSK3) controls deoxyglucose-induced mitochondrial biogenesis in human neuroblastoma SH-SY5Y cells. Mitochondrion. 2014;14:54-63 pubmed 出版商

Jesus P, Ouelaa W, François M, Riachy L, Guérin C, Aziz M, et al. Alteration of intestinal barrier function during activity-based anorexia in mice. Clin Nutr. 2014;33:1046-53 pubmed 出版商

Battle M, Gillespie C, Quarshie A, Lanier V, Harmon T, Wilson K, et al. Obesity induced a leptin-Notch signaling axis in breast cancer. Int J Cancer. 2014;134:1605-16 pubmed 出版商

Fernandez S, Genis L, Torres Aleman I. A phosphatase-independent gain-of-function mutation in PTEN triggers aberrant cell growth in astrocytes through an autocrine IGF-1 loop. Oncogene. 2014;33:4114-22 pubmed 出版商

Whittington R, Bretteville A, Virag L, Emala C, Maurin T, Marcouiller F, et al. Anesthesia-induced hypothermia mediates decreased ARC gene and protein expression through ERK/MAPK inactivation. Sci Rep. 2013;3:1388 pubmed 出版商

Yoshida R, Nagata M, Nakayama H, Niimori Kita K, Hassan W, Tanaka T, et al. The pathological significance of Notch1 in oral squamous cell carcinoma. Lab Invest. 2013;93:1068-81 pubmed 出版商

Campbell M, Karaca M, Adamski K, Chorley B, Wang X, Bell D. Novel hematopoietic target genes in the NRF2-mediated transcriptional pathway. Oxid Med Cell Longev. 2013;2013:120305 pubmed 出版商

Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed 出版商

Huebbers C, Preuss S, Kolligs J, Vent J, Stenner M, Wieland U, et al. Integration of HPV6 and downregulation of AKR1C3 expression mark malignant transformation in a patient with juvenile-onset laryngeal papillomatosis. PLoS ONE. 2013;8:e57207 pubmed 出版商

Tuul M, Kitao H, Iimori M, Matsuoka K, Kiyonari S, Saeki H, et al. Rad9, Rad17, TopBP1 and claspin play essential roles in heat-induced activation of ATR kinase and heat tolerance. PLoS ONE. 2013;8:e55361 pubmed 出版商

Forand A, Beck L, Leroy C, Rousseau A, Boitez V, Cohen I, et al. EKLF-driven PIT1 expression is critical for mouse erythroid maturation in vivo and in vitro. Blood. 2013;121:666-78 pubmed 出版商

Kim Y, Remacle A, Chernov A, Liu H, Shubayev I, Lai C, et al. The MMP-9/TIMP-1 axis controls the status of differentiation and function of myelin-forming Schwann cells in nerve regeneration. PLoS ONE. 2012;7:e33664 pubmed 出版商

Kenneth N, Younger J, Hughes E, Marcotte D, Barker P, Saunders T, et al. An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1. Biochem J. 2012;443:355-9 pubmed 出版商

Ewald F, Ueffing N, Brockmann L, Hader C, Telieps T, Schuster M, et al. The role of c-FLIP splice variants in urothelial tumours. Cell Death Dis. 2011;2:e245 pubmed 出版商

Bloch J, Kaeser M, Sadeghi Y, Rouiller E, Redmond D, Brunet J. Doublecortin-positive cells in the adult primate cerebral cortex and possible role in brain plasticity and development. J Comp Neurol. 2011;519:775-89 pubmed 出版商

Foster C, Dovey O, Lezina L, Luo J, Gant T, Barlev N, et al. Lysine-specific demethylase 1 regulates the embryonic transcriptome and CoREST stability. Mol Cell Biol. 2010;30:4851-63 pubmed 出版商

Roblek M, Schüchner S, Huber V, Ollram K, Vlcek Vesely S, Foisner R, et al. Monoclonal antibodies specific for disease-associated point-mutants: lamin A/C R453W and R482W. PLoS ONE. 2010;5:e10604 pubmed 出版商

Garver W, Jelinek D, Francis G, Murphy B. The Niemann-Pick C1 gene is downregulated by feedback inhibition of the SREBP pathway in human fibroblasts. J Lipid Res. 2008;49:1090-102 pubmed 出版商

Lagger G, Doetzlhofer A, Schuettengruber B, Haidweger E, Simboeck E, Tischler J, et al. The tumor suppressor p53 and histone deacetylase 1 are antagonistic regulators of the cyclin-dependent kinase inhibitor p21/WAF1/CIP1 gene. Mol Cell Biol. 2003;23:2669-79 pubmed

Ma J, Chang K, Peng J, Shi Q, Gan H, Gao K, et al. SPOP promotes ATF2 ubiquitination and degradation to suppress prostate cancer progression. J Exp Clin Cancer Res. 2018;37:145 pubmed 出版商

Lehmer C, Schludi M, Ransom L, Greiling J, Junghänel M, Exner N, et al. A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS. EMBO Mol Med. 2018;10: pubmed 出版商

Jeong J, Lee D, Liu S, Chua S, Schwartz G, Jo Y. Activation of temperature-sensitive TRPV1-like receptors in ARC POMC neurons reduces food intake. PLoS Biol. 2018;16:e2004399 pubmed 出版商

Zhou P, Ding X, Wan X, Liu L, Yuan X, Zhang W, et al. MLL5 suppresses antiviral innate immune response by facilitating STUB1-mediated RIG-I degradation. Nat Commun. 2018;9:1243 pubmed 出版商

Weng L, Han Y, Enomoto A, Kitaura Y, Nagamori S, Kanai Y, et al. Negative regulation of amino acid signaling by MAPK-regulated 4F2hc/Girdin complex. PLoS Biol. 2018;16:e2005090 pubmed 出版商

Herling C, Abedpour N, Weiss J, Schmitt A, Jachimowicz R, Merkel O, et al. Clonal dynamics towards the development of venetoclax resistance in chronic lymphocytic leukemia. Nat Commun. 2018;9:727 pubmed 出版商

Tiwari A, Addis Jones O, Chan K. 53BP1 can limit sister-chromatid rupture and rearrangements driven by a distinct ultrafine DNA bridging-breakage process. Nat Commun. 2018;9:677 pubmed 出版商

Kitowska K, Kowalska A, Mieszkowska M, Piasecka D, Skladanowski A, Romanska H, et al. Progesterone impairs Herceptin effect on breast cancer cells. Oncol Lett. 2018;15:1817-1822 pubmed 出版商

Goiran T, Duplan E, Rouland L, El Manaa W, Lauritzen I, Dunys J, et al. Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation. Cell Death Differ. 2018;25:873-884 pubmed 出版商

Chen J, Guccini I, Di Mitri D, Brina D, Revandkar A, Sarti M, et al. Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer. Nat Genet. 2018;50:219-228 pubmed 出版商

Bu Y, Yoshida A, Chitnis N, Altman B, Tameire F, Oran A, et al. A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival. Nat Cell Biol. 2018;20:104-115 pubmed 出版商

Wallot Hieke N, Verma N, Schlütermann D, Berleth N, Deitersen J, Böhler P, et al. Systematic analysis of ATG13 domain requirements for autophagy induction. Autophagy. 2018;14:743-763 pubmed 出版商

Venkataramani V, Küffer S, Cheung K, Jiang X, Trumper L, Wulf G, et al. CD31 Expression Determines Redox Status and Chemoresistance in Human Angiosarcomas. Clin Cancer Res. 2018;24:460-473 pubmed 出版商

Garcia Esparcia P, Koneti A, Rodríguez Oroz M, Gago B, del Río J, Ferrer I. Mitochondrial activity in the frontal cortex area 8 and angular gyrus in Parkinson's disease and Parkinson's disease with dementia. Brain Pathol. 2018;28:43-57 pubmed 出版商

Yu X, Liang Q, Liu W, Zhou L, Li W, Liu H. Deguelin, an Aurora B Kinase Inhibitor, Exhibits Potent Anti-Tumor Effect in Human Esophageal Squamous Cell Carcinoma. EBioMedicine. 2017;26:100-111 pubmed 出版商

Blakely C, Watkins T, Wu W, Gini B, Chabon J, McCoach C, et al. Evolution and clinical impact of co-occurring genetic alterations in advanced-stage EGFR-mutant lung cancers. Nat Genet. 2017;49:1693-1704 pubmed 出版商

Zhao L, Liu J, He C, Yan R, Zhou K, Cui Q, et al. Protein kinase A determines platelet life span and survival by regulating apoptosis. J Clin Invest. 2017;127:4338-4351 pubmed 出版商

Bartolomé A, García Aguilar A, Asahara S, Kido Y, Guillen C, Pajvani U, et al. MTORC1 Regulates both General Autophagy and Mitophagy Induction after Oxidative Phosphorylation Uncoupling. Mol Cell Biol. 2017;: pubmed 出版商

Chen D, Xiang Q, Nicholas J. Human Herpesvirus 8 Interleukin-6 Interacts with Calnexin Cycle Components and Promotes Protein Folding. J Virol. 2017;91: pubmed 出版商

Turczyk L, Kitowska K, Mieszkowska M, Mieczkowski K, Czaplinska D, Piasecka D, et al. FGFR2-Driven Signaling Counteracts Tamoxifen Effect on ER?-Positive Breast Cancer Cells. Neoplasia. 2017;19:791-804 pubmed 出版商

Valsecchi F, Konràd C, D Aurelio M, Ramos Espiritu L, Stepanova A, Burstein S, et al. Distinct intracellular sAC-cAMP domains regulate ER Ca2+ signaling and OXPHOS function. J Cell Sci. 2017;130:3713-3727 pubmed 出版商

Widjaja C, Olvera J, Metz P, Phan A, Savas J, de Bruin G, et al. Proteasome activity regulates CD8+ T lymphocyte metabolism and fate specification. J Clin Invest. 2017;127:3609-3623 pubmed 出版商

Willén K, Edgar J, Hasegawa T, Tanaka N, Futter C, Gouras G. A? accumulation causes MVB enlargement and is modelled by dominant negative VPS4A. Mol Neurodegener. 2017;12:61 pubmed 出版商

Jin L, Vu T, Yuan G, Datta P. STRAP Promotes Stemness of Human Colorectal Cancer via Epigenetic Regulation of the NOTCH Pathway. Cancer Res. 2017;77:5464-5478 pubmed 出版商

Lee J, Jeon Y, Lee K, Lee H, Park J, Jang H, et al. RNF20 Suppresses Tumorigenesis by Inhibiting SREBP1c-PTTG1 Axis in Kidney Cancer. Mol Cell Biol. 2017;: pubmed 出版商

Tanaka N, Patel A, Tang L, Silver N, Lindemann A, Takahashi H, et al. Replication Stress Leading to Apoptosis within the S-phase Contributes to Synergism between Vorinostat and AZD1775 in HNSCC Harboring High-Risk TP53 Mutation. Clin Cancer Res. 2017;23:6541-6554 pubmed 出版商

Hughes M, Lavrencic P, Coll R, Ve T, Ryan D, Williams N, et al. Solution structure of the TLR adaptor MAL/TIRAP reveals an intact BB loop and supports MAL Cys91 glutathionylation for signaling. Proc Natl Acad Sci U S A. 2017;114:E6480-E6489 pubmed 出版商

Lin D, Cherepanova N, Bozzacco L, Macdonald M, Gilmore R, Tai A. Dengue Virus Hijacks a Noncanonical Oxidoreductase Function of a Cellular Oligosaccharyltransferase Complex. MBio. 2017;8: pubmed 出版商

Guan W, Guyot R, Samarut J, Flamant F, Wong J, Gauthier K. Methylcytosine dioxygenase TET3 interacts with thyroid hormone nuclear receptors and stabilizes their association to chromatin. Proc Natl Acad Sci U S A. 2017;114:8229-8234 pubmed 出版商

Jiang P, Li Y, Poleshko A, Medvedeva V, Baulina N, Zhang Y, et al. The Protein Encoded by the CCDC170 Breast Cancer Gene Functions to Organize the Golgi-Microtubule Network. EBioMedicine. 2017;22:28-43 pubmed 出版商

Stefani C, González Rodríguez D, Senju Y, Doye A, Efimova N, Janel S, et al. Ezrin enhances line tension along transcellular tunnel edges via NMIIa driven actomyosin cable formation. Nat Commun. 2017;8:15839 pubmed 出版商

Schommartz T, Tang J, Brost R, Brune W. Differential Requirement of Human Cytomegalovirus UL112-113 Protein Isoforms for Viral Replication. J Virol. 2017;91: pubmed 出版商

Rolland D, Basrur V, Jeon Y, McNeil Schwalm C, Fermin D, Conlon K, et al. Functional proteogenomics reveals biomarkers and therapeutic targets in lymphomas. Proc Natl Acad Sci U S A. 2017;114:6581-6586 pubmed 出版商

Li L, Fan L, Zhou J, Grantham J, Calvet J, Sage J, et al. Lysine methyltransferase SMYD2 promotes cyst growth in autosomal dominant polycystic kidney disease. J Clin Invest. 2017;127:2751-2764 pubmed 出版商

Ding L, Wang Q, Shen M, Sun Y, Zhang X, Huang C, et al. Thermoresponsive nanocomposite gel for local drug delivery to suppress the growth of glioma by inducing autophagy. Autophagy. 2017;13:1176-1190 pubmed 出版商

Tchasovnikarova I, Timms R, Douse C, Roberts R, Dougan G, Kingston R, et al. Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2. Nat Genet. 2017;49:1035-1044 pubmed 出版商

Lewis K, Valanejad L, Cast A, Wright M, Wei C, Iakova P, et al. RNA Binding Protein CUGBP1 Inhibits Liver Cancer in a Phosphorylation-Dependent Manner. Mol Cell Biol. 2017;37: pubmed 出版商

Good C, Madzo J, Patel B, Maegawa S, Engel N, Jelinek J, et al. A novel isoform of TET1 that lacks a CXXC domain is overexpressed in cancer. Nucleic Acids Res. 2017;45:8269-8281 pubmed 出版商

Domae E, Hirai Y, Ikeo T, Goda S, Shimizu Y. Cytokine-mediated activation of human ex vivo-expanded V?9V?2 T cells. Oncotarget. 2017;8:45928-45942 pubmed 出版商

Zike I, Chohan M, Kopelman J, Krasnow E, Flicker D, Nautiyal K, et al. OCD candidate gene SLC1A1/EAAT3 impacts basal ganglia-mediated activity and stereotypic behavior. Proc Natl Acad Sci U S A. 2017;114:5719-5724 pubmed 出版商

Yu P, Wilhelm K, Dubrac A, Tung J, Alves T, Fang J, et al. FGF-dependent metabolic control of vascular development. Nature. 2017;545:224-228 pubmed 出版商

Zhong Y, Wang J, Henderson M, Yang P, Hagen B, Siddique T, et al. Nuclear export of misfolded SOD1 mediated by a normally buried NES-like sequence reduces proteotoxicity in the nucleus. elife. 2017;6: pubmed 出版商

Acharya D, Hainer S, Yoon Y, Wang F, Bach I, Rivera Pérez J, et al. KAT-Independent Gene Regulation by Tip60 Promotes ESC Self-Renewal but Not Pluripotency. Cell Rep. 2017;19:671-679 pubmed 出版商

Hung V, Lam S, Udeshi N, Svinkina T, Guzman G, Mootha V, et al. Proteomic mapping of cytosol-facing outer mitochondrial and ER membranes in living human cells by proximity biotinylation. elife. 2017;6: pubmed 出版商

Salsman J, Stathakis A, Parker E, Chung D, Anthes L, Koskowich K, et al. PML nuclear bodies contribute to the basal expression of the mTOR inhibitor DDIT4. Sci Rep. 2017;7:45038 pubmed 出版商

Lee H, Kim M, Baek M, Morales L, Jang I, Slaga T, et al. Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development. Sci Rep. 2017;7:45077 pubmed 出版商

Xu D, Jin J, Yu H, Zhao Z, Ma D, Zhang C, et al. Chrysin inhibited tumor glycolysis and induced apoptosis in hepatocellular carcinoma by targeting hexokinase-2. J Exp Clin Cancer Res. 2017;36:44 pubmed 出版商

Weber M, Wu T, Meilandt W, Dominguez S, Solanoy H, Maloney J, et al. BACE1 across species: a comparison of the in vivo consequences of BACE1 deletion in mice and rats. Sci Rep. 2017;7:44249 pubmed 出版商

Kim J, Hyun H, Min S, Kang T. Sustained HSP25 Expression Induces Clasmatodendrosis via ER Stress in the Rat Hippocampus. Front Cell Neurosci. 2017;11:47 pubmed 出版商

Ariyoshi M, Katane M, Hamase K, Miyoshi Y, Nakane M, Hoshino A, et al. D-Glutamate is metabolized in the heart mitochondria. Sci Rep. 2017;7:43911 pubmed 出版商

Nikolic I, Andjelkovic M, Zaric M, Zelen I, Canovic P, Milosavljević Z, et al. Induction of mitochondrial apoptotic pathway by raloxifene and estrogen in human endometrial stromal ThESC cell line. Arch Med Sci. 2017;13:293-301 pubmed 出版商

Li J, Qu J, Shi Y, Perfetto M, Ping Z, Christian L, et al. Nicotinic acid inhibits glioma invasion by facilitating Snail1 degradation. Sci Rep. 2017;7:43173 pubmed 出版商

Barilari M, Bonfils G, Treins C, Koka V, De Villeneuve D, Fabrega S, et al. ZRF1 is a novel S6 kinase substrate that drives the senescence programme. EMBO J. 2017;36:736-750 pubmed 出版商

Wu H, Zhao X, Wang F, Jiang Q, Shi L, Gong M, et al. Mouse Testicular Cell Type-Specific Antiviral Response against Mumps Virus Replication. Front Immunol. 2017;8:117 pubmed 出版商

Carmona V, Cunha Santos J, Onofre I, Simões A, Vijayakumar U, Davidson B, et al. Unravelling Endogenous MicroRNA System Dysfunction as a New Pathophysiological Mechanism in Machado-Joseph Disease. Mol Ther. 2017;25:1038-1055 pubmed 出版商

Vazquez Cintron E, Beske P, Tenezaca L, Tran B, Oyler J, Glotfelty E, et al. Engineering Botulinum Neurotoxin C1 as a Molecular Vehicle for Intra-Neuronal Drug Delivery. Sci Rep. 2017;7:42923 pubmed 出版商

Guitart A, Panagopoulou T, Villacreces A, Vukovic M, Sepúlveda C, Allen L, et al. Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions. J Exp Med. 2017;214:719-735 pubmed 出版商

Maskey R, Flatten K, Sieben C, Peterson K, Baker D, Nam H, et al. Spartan deficiency causes accumulation of Topoisomerase 1 cleavage complexes and tumorigenesis. Nucleic Acids Res. 2017;45:4564-4576 pubmed 出版商

Kim J, Ko A, Hyun H, Min S, Kim J. PDI regulates seizure activity via NMDA receptor redox in rats. Sci Rep. 2017;7:42491 pubmed 出版商

Choi E, Yoon S, Hahn Y, Kim K. Cellular Dynamics of Rad51 and Rad54 in Response to Postreplicative Stress and DNA Damage in HeLa Cells. Mol Cells. 2017;40:143-150 pubmed 出版商

Guhathakurta S, Evangelista B, Ghosh S, Basu S, Kim Y. Hypomethylation of intron1 of ?-synuclein gene does not correlate with Parkinson's disease. Mol Brain. 2017;10:6 pubmed 出版商

Mondello P, Derenzini E, Asgari Z, Philip J, Brea E, SESHAN V, et al. Dual inhibition of histone deacetylases and phosphoinositide 3-kinase enhances therapeutic activity against B cell lymphoma. Oncotarget. 2017;8:14017-14028 pubmed 出版商

Nakasuji T, Ogonuki N, Chiba T, Kato T, Shiozawa K, Yamatoya K, et al. Complementary Critical Functions of Zfy1 and Zfy2 in Mouse Spermatogenesis and Reproduction. PLoS Genet. 2017;13:e1006578 pubmed 出版商

Panic A, Ketteler J, Reis H, Sak A, Herskind C, Maier P, et al. Progression-related loss of stromal Caveolin 1 levels fosters the growth of human PC3 xenografts and mediates radiation resistance. Sci Rep. 2017;7:41138 pubmed 出版商

Ramalingam D, Ziegelbauer J. Viral microRNAs Target a Gene Network, Inhibit STAT Activation, and Suppress Interferon Responses. Sci Rep. 2017;7:40813 pubmed 出版商

Nelms B, Dalomba N, Lencer W. A targeted RNAi screen identifies factors affecting diverse stages of receptor-mediated transcytosis. J Cell Biol. 2017;216:511-525 pubmed 出版商

Ysselstein D, Dehay B, Costantino I, McCabe G, Frosch M, George J, et al. Endosulfine-alpha inhibits membrane-induced α-synuclein aggregation and protects against α-synuclein neurotoxicity. Acta Neuropathol Commun. 2017;5:3 pubmed 出版商

Lin Y, Jean Y, Lee H, Lin S, Pan C, Chen W, et al. Excavatolide B Attenuates Rheumatoid Arthritis through the Inhibition of Osteoclastogenesis. Mar Drugs. 2017;15: pubmed 出版商

Kim J, Shin S, Seo J, Lee E, Jeong M, Lee M, et al. C-terminus of HSC70-Interacting Protein (CHIP) Inhibits Adipocyte Differentiation via Ubiquitin- and Proteasome-Mediated Degradation of PPARγ. Sci Rep. 2017;7:40023 pubmed 出版商

Wang J, Xu Y, Li L, Wang L, Yao R, Sun Q, et al. FOXC1 is associated with estrogen receptor alpha and affects sensitivity of tamoxifen treatment in breast cancer. Cancer Med. 2017;6:275-287 pubmed 出版商

Rao S, Snaith A, Marino D, Cheng X, Lwin S, Orriss I, et al. Tumour-derived alkaline phosphatase regulates tumour growth, epithelial plasticity and disease-free survival in metastatic prostate cancer. Br J Cancer. 2017;116:227-236 pubmed 出版商

Dawar S, Lim Y, Puccini J, White M, Thomas P, Bouchier Hayes L, et al. Caspase-2-mediated cell death is required for deleting aneuploid cells. Oncogene. 2017;36:2704-2714 pubmed 出版商

Nuzzo A, Giuffrida D, Masturzo B, Mele P, Piccoli E, Eva C, et al. Altered expression of G1/S phase cell cycle regulators in placental mesenchymal stromal cells derived from preeclamptic pregnancies with fetal-placental compromise. Cell Cycle. 2017;16:200-212 pubmed 出版商

Søndergaard M, Liu Y, Larsen K, Nani A, Tian X, Holt C, et al. The Arrhythmogenic Calmodulin p.Phe142Leu Mutation Impairs C-domain Ca2+ Binding but Not Calmodulin-dependent Inhibition of the Cardiac Ryanodine Receptor. J Biol Chem. 2017;292:1385-1395 pubmed 出版商

Yamamoto K, Sato K, Yukita M, Yasuda M, Omodaka K, Ryu M, et al. The neuroprotective effect of latanoprost acts via klotho-mediated suppression of calpain activation after optic nerve transection. J Neurochem. 2017;140:495-508 pubmed 出版商

Chan D, Hui W, Wang J, Yung M, Hui L, Qin Y, et al. DLX1 acts as a crucial target of FOXM1 to promote ovarian cancer aggressiveness by enhancing TGF-β/SMAD4 signaling. Oncogene. 2017;36:1404-1416 pubmed 出版商

Wójtowicz A, Szychowski K, Wnuk A, Kajta M. Dibutyl Phthalate (DBP)-Induced Apoptosis and Neurotoxicity are Mediated via the Aryl Hydrocarbon Receptor (AhR) but not by Estrogen Receptor Alpha (ERα), Estrogen Receptor Beta (ERβ), or Peroxisome Proliferator-Activated Receptor Gamma (PPARγ) in Mo. Neurotox Res. 2017;31:77-89 pubmed 出版商

Svinka J, Pflügler S, Mair M, Marschall H, Hengstler J, Stiedl P, et al. Epidermal growth factor signaling protects from cholestatic liver injury and fibrosis. J Mol Med (Berl). 2017;95:109-117 pubmed 出版商

Wurster K, Hummel F, Richter J, Giefing M, Hartmann S, Hansmann M, et al. Inactivation of the putative ubiquitin-E3 ligase PDLIM2 in classical Hodgkin and anaplastic large cell lymphoma. Leukemia. 2017;31:602-613 pubmed 出版商

Peng L, Hu Y, Chen D, Linghu R, Wang Y, Kou X, et al. Ubiquitin specific protease 21 upregulation in breast cancer promotes cell tumorigenic capability and is associated with the NOD-like receptor signaling pathway. Oncol Lett. 2016;12:4531-4537 pubmed 出版商

Ellinger J, Gromes A, Poss M, Brüggemann M, Schmidt D, Ellinger N, et al. Systematic expression analysis of the mitochondrial complex III subunits identifies UQCRC1 as biomarker in clear cell renal cell carcinoma. Oncotarget. 2016;7:86490-86499 pubmed 出版商

Kueh H, Zhu Y, Shi J. A simplified Bcl-2 network model reveals quantitative determinants of cell-to-cell variation in sensitivity to anti-mitotic chemotherapeutics. Sci Rep. 2016;6:36585 pubmed 出版商

Thurston T, Matthews S, Jennings E, Alix E, Shao F, Shenoy A, et al. Growth inhibition of cytosolic Salmonella by caspase-1 and caspase-11 precedes host cell death. Nat Commun. 2016;7:13292 pubmed 出版商

Balmus G, Barros A, Wijnhoven P, Lescale C, Hasse H, Boroviak K, et al. Synthetic lethality between PAXX and XLF in mammalian development. Genes Dev. 2016;30:2152-2157 pubmed

Veyrat M, Durand S, Classe M, Glavan T, Oker N, Kapetanakis N, et al. Stimulation of the toll-like receptor 3 promotes metabolic reprogramming in head and neck carcinoma cells. Oncotarget. 2016;7:82580-82593 pubmed 出版商

Yue G, Xie S, Lee J, Kwok H, Gao S, Nian Y, et al. New potential beneficial effects of actein, a triterpene glycoside isolated from Cimicifuga species, in breast cancer treatment. Sci Rep. 2016;6:35263 pubmed 出版商

Pigoni M, Wanngren J, Kuhn P, Munro K, Gunnersen J, Takeshima H, et al. Seizure protein 6 and its homolog seizure 6-like protein are physiological substrates of BACE1 in neurons. Mol Neurodegener. 2016;11:67 pubmed

Yoshida N, Comte D, Mizui M, Otomo K, Rosetti F, Mayadas T, et al. ICER is requisite for Th17 differentiation. Nat Commun. 2016;7:12993 pubmed 出版商

Ijaz T, Wakamiya M, Sun H, Recinos A, Tilton R, Brasier A. Generation and characterization of a novel transgenic mouse harboring conditional nuclear factor-kappa B/RelA knockout alleles. BMC Dev Biol. 2016;16:32 pubmed

Kasula R, Chai Y, Bademosi A, Harper C, Gormal R, Morrow I, et al. The Munc18-1 domain 3a hinge-loop controls syntaxin-1A nanodomain assembly and engagement with the SNARE complex during secretory vesicle priming. J Cell Biol. 2016;214:847-58 pubmed 出版商

Delbridge A, Pang S, Vandenberg C, Grabow S, Aubrey B, Tai L, et al. RAG-induced DNA lesions activate proapoptotic BIM to suppress lymphomagenesis in p53-deficient mice. J Exp Med. 2016;213:2039-48 pubmed 出版商

de Wit R, Mujić Delić A, van Senten J, Fraile Ramos A, Siderius M, Smit M. Human cytomegalovirus encoded chemokine receptor US28 activates the HIF-1α/PKM2 axis in glioblastoma cells. Oncotarget. 2016;7:67966-67985 pubmed 出版商

Nieto Soler M, Morgado Palacin I, Lafarga V, Lecona E, Murga M, Callen E, et al. Efficacy of ATR inhibitors as single agents in Ewing sarcoma. Oncotarget. 2016;7:58759-58767 pubmed 出版商

Eberhardt A, Hansen J, Koster J, Lotta L, Wang S, Livingstone E, et al. Protein arginine methyltransferase 1 is a novel regulator of MYCN in neuroblastoma. Oncotarget. 2016;7:63629-63639 pubmed 出版商

Martin Martin N, Piva M, Urosevic J, Aldaz P, Sutherland J, Fernandez Ruiz S, et al. Stratification and therapeutic potential of PML in metastatic breast cancer. Nat Commun. 2016;7:12595 pubmed 出版商

Jungas T, Perchey R, Fawal M, Callot C, Froment C, Burlet Schiltz O, et al. Eph-mediated tyrosine phosphorylation of citron kinase controls abscission. J Cell Biol. 2016;214:555-69 pubmed 出版商

Park J, Park J, Ahn J, Kim J, Won M, Lee C. Age?dependent increase in the expression of antioxidant?like protein?1 in the gerbil hippocampus. Mol Med Rep. 2016;14:3215-9 pubmed 出版商

Wei Y, Melas P, Villaescusa J, Liu J, Xu N, Christiansen S, et al. MicroRNA 101b Is Downregulated in the Prefrontal Cortex of a Genetic Model of Depression and Targets the Glutamate Transporter SLC1A1 (EAAT3) in Vitro. Int J Neuropsychopharmacol. 2016;19: pubmed 出版商

Hashimoto K, Sharma V, Sasanuma H, Tian X, Takata M, Takeda S, et al. Poor recognition of O6-isopropyl dG by MGMT triggers double strand break-mediated cell death and micronucleus induction in FANC-deficient cells. Oncotarget. 2016;7:59795-59808 pubmed 出版商

She Q, Gruvberger Saal S, Maurer M, Chen Y, Jumppanen M, Su T, et al. Integrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer. BMC Cancer. 2016;16:587 pubmed 出版商

Sun H, Liang L, Li Y, Feng C, Li L, Zhang Y, et al. Lysine-specific histone demethylase 1 inhibition promotes reprogramming by facilitating the expression of exogenous transcriptional factors and metabolic switch. Sci Rep. 2016;6:30903 pubmed 出版商

Liu W, Kang S, Huang Z, Wu C, Jin H, Maine C, et al. A miR-155-Peli1-c-Rel pathway controls the generation and function of T follicular helper cells. J Exp Med. 2016;213:1901-19 pubmed 出版商

Czaplinska D, Mieczkowski K, Supernat A, Skladanowski A, Kordek R, Biernat W, et al. Interactions between FGFR2 and RSK2-implications for breast cancer prognosis. Tumour Biol. 2016;37:13721-13731 pubmed

Liu H, Li W, Yu X, Gao F, Duan Z, Ma X, et al. EZH2-mediated Puma gene repression regulates non-small cell lung cancer cell proliferation and cisplatin-induced apoptosis. Oncotarget. 2016;7:56338-56354 pubmed 出版商

Kowluru R, Shan Y, Mishra M. Dynamic DNA methylation of matrix metalloproteinase-9 in the development of diabetic retinopathy. Lab Invest. 2016;96:1040-9 pubmed 出版商

Brenner C, Luciani J, Bizet M, Ndlovu M, Josseaux E, Dedeurwaerder S, et al. The interplay between the lysine demethylase KDM1A and DNA methyltransferases in cancer cells is cell cycle dependent. Oncotarget. 2016;7:58939-58952 pubmed 出版商

Kim S, Das A, Chai J, Binas B, Choi M, Park K, et al. Transcriptome sequencing wide functional analysis of human mesenchymal stem cells in response to TLR4 ligand. Sci Rep. 2016;6:30311 pubmed 出版商

Mansouri S, Singh S, Alamsahebpour A, Burrell K, Li M, Karabork M, et al. DICER governs characteristics of glioma stem cells and the resulting tumors in xenograft mouse models of glioblastoma. Oncotarget. 2016;7:56431-56446 pubmed 出版商

Jin H, Hong S, Park J, Chang Y, Hong Y, Park I, et al. Inhibition of JNK-mediated autophagy enhances NSCLC cell sensitivity to mTORC1/2 inhibitors. Sci Rep. 2016;6:28945 pubmed 出版商

Xie Y, Lu W, Liu S, Yang Q, Goodwin J, Sathyanarayana S, et al. MMP7 interacts with ARF in nucleus to potentiate tumor microenvironments for prostate cancer progression in vivo. Oncotarget. 2016;7:47609-47619 pubmed 出版商

van Veen J, Pringle D, McMahon M. P2A-Fluorophore Tagging of BRAF Tightly Links Expression to Fluorescence In Vivo. PLoS ONE. 2016;11:e0157661 pubmed 出版商

Legeay S, Clere N, Hilairet G, Do Q, Bernard P, Quignard J, et al. The insect repellent N,N-diethyl-m-toluamide (DEET) induces angiogenesis via allosteric modulation of the M3 muscarinic receptor in endothelial cells. Sci Rep. 2016;6:28546 pubmed 出版商

Shi Y, Wu W, Qiao H, Yue L, Ren L, Zhang S, et al. The protein PprI provides protection against radiation injury in human and mouse cells. Sci Rep. 2016;6:26664 pubmed 出版商

Kaur E, Sahu A, Hole A, Rajendra J, Chaubal R, Gardi N, et al. Unique spectral markers discern recurrent Glioblastoma cells from heterogeneous parent population. Sci Rep. 2016;6:26538 pubmed 出版商

Ahn J, Chen B, Shin B, Lee T, Cho J, Kim I, et al. Comparison of catalase immunoreactivity in the hippocampus between young, adult and aged mice and rats. Mol Med Rep. 2016;14:851-6 pubmed 出版商

Stein S, Mack E, Rome K, Pajcini K, Ohtani T, Xu L, et al. Trib2 Suppresses Tumor Initiation in Notch-Driven T-ALL. PLoS ONE. 2016;11:e0155408 pubmed 出版商

Rogers J, Vo U, Buret L, Pang T, Meiklejohn H, Zeleznikow Johnston A, et al. Dissociating the therapeutic effects of environmental enrichment and exercise in a mouse model of anxiety with cognitive impairment. Transl Psychiatry. 2016;6:e794 pubmed 出版商

Lipinski K, Britschgi C, Schrader K, Christinat Y, Frischknecht L, Krek W. Colorectal cancer cells display chaperone dependency for the unconventional prefoldin URI1. Oncotarget. 2016;7:29635-47 pubmed 出版商

Oda K, Yatera K, Izumi H, Ishimoto H, Yamada S, Nakao H, et al. Profibrotic role of WNT10A via TGF-? signaling in idiopathic pulmonary fibrosis. Respir Res. 2016;17:39 pubmed 出版商

Piemontese M, Onal M, Xiong J, Han L, Thostenson J, Almeida M, et al. Low bone mass and changes in the osteocyte network in mice lacking autophagy in the osteoblast lineage. Sci Rep. 2016;6:24262 pubmed 出版商

Wang X, Liu J, Jiang L, Wei X, Niu C, Wang R, et al. Bach1 Induces Endothelial Cell Apoptosis and Cell-Cycle Arrest through ROS Generation. Oxid Med Cell Longev. 2016;2016:6234043 pubmed 出版商

Chen G, Luo Y, Eriksson D, Meng X, Qian C, Bauerle T, et al. High fat diet increases melanoma cell growth in the bone marrow by inducing osteopontin and interleukin 6. Oncotarget. 2016;7:26653-69 pubmed 出版商

Prokesch A, Pelzmann H, Pessentheiner A, Huber K, Madreiter Sokolowski C, Drougard A, et al. N-acetylaspartate catabolism determines cytosolic acetyl-CoA levels and histone acetylation in brown adipocytes. Sci Rep. 2016;6:23723 pubmed 出版商

Ullrich M, Bergmann R, Peitzsch M, Zenker E, Cartellieri M, Bachmann M, et al. Multimodal Somatostatin Receptor Theranostics Using [(64)Cu]Cu-/[(177)Lu]Lu-DOTA-(Tyr(3))octreotate and AN-238 in a Mouse Pheochromocytoma Model. Theranostics. 2016;6:650-65 pubmed 出版商

Richarson A, Scott D, Zagnitko O, Aza Blanc P, Chang C, Russler Germain D. Registered report: IDH mutation impairs histone demethylation and results in a block to cell differentiation. elife. 2016;5:e10860 pubmed 出版商

Chen Y, Fang Q, Wang Z, Zhang J, Macleod A, Hall R, et al. Transient Receptor Potential Vanilloid 4 Ion Channel Functions as a Pruriceptor in Epidermal Keratinocytes to Evoke Histaminergic Itch. J Biol Chem. 2016;291:10252-62 pubmed 出版商

Tiffen J, Wilson S, Gallagher S, Hersey P, Filipp F. Somatic Copy Number Amplification and Hyperactivating Somatic Mutations of EZH2 Correlate With DNA Methylation and Drive Epigenetic Silencing of Genes Involved in Tumor Suppression and Immune Responses in Melanoma. Neoplasia. 2016;18:121-32 pubmed 出版商

Gorres K, Daigle D, Mohanram S, McInerney G, Lyons D, Miller G. Valpromide Inhibits Lytic Cycle Reactivation of Epstein-Barr Virus. MBio. 2016;7:e00113 pubmed 出版商

Martino Echarri E, Brocardo M, Mills K, Henderson B. Tankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of β-Catenin Degradation-Competent Axin Puncta. PLoS ONE. 2016;11:e0150484 pubmed 出版商

Batth I, Yun H, Hussain S, Meng P, Osmulski P, Huang T, et al. Crosstalk between RON and androgen receptor signaling in the development of castration resistant prostate cancer. Oncotarget. 2016;7:14048-63 pubmed 出版商

Cott C, Thuenauer R, Landi A, Kühn K, Juillot S, Imberty A, et al. Pseudomonas aeruginosa lectin LecB inhibits tissue repair processes by triggering β-catenin degradation. Biochim Biophys Acta. 2016;1863:1106-18 pubmed 出版商

Choi H, Ahn J, Park J, Won M, Lee C. Age-dependent changes in the protein expression levels of Redd1 and mTOR in the gerbil hippocampus during normal aging. Mol Med Rep. 2016;13:2409-14 pubmed 出版商

Egawa H, Jingushi K, Hirono T, Ueda Y, Kitae K, Nakata W, et al. The miR-130 family promotes cell migration and invasion in bladder cancer through FAK and Akt phosphorylation by regulating PTEN. Sci Rep. 2016;6:20574 pubmed 出版商

Schrödter S, Braun M, Syring I, Klümper N, Deng M, Schmidt D, et al. Identification of the dopamine transporter SLC6A3 as a biomarker for patients with renal cell carcinoma. Mol Cancer. 2016;15:10 pubmed 出版商

Shi Y, Liu T, Fu J, Xu W, Wu L, Hou A, et al. Vitamin D/VDR signaling attenuates lipopolysaccharide‑induced acute lung injury by maintaining the integrity of the pulmonary epithelial barrier. Mol Med Rep. 2016;13:1186-94 pubmed 出版商

Zhang H, Zhan C, Ke J, Xue Z, Zhang A, Xu K, et al. EGFR kinase domain mutation positive lung cancers are sensitive to intrapleural perfusion with hyperthermic chemotherapy (IPHC) complete treatment. Oncotarget. 2016;7:3367-78 pubmed 出版商

Spina R, Voss D, Asnaghi L, Sloan A, Bar E. Atracurium Besylate and other neuromuscular blocking agents promote astroglial differentiation and deplete glioblastoma stem cells. Oncotarget. 2016;7:459-72 pubmed 出版商

Krieger J, Arnold M, Pettersen K, Lossel P, Langhans W, Lee S. Knockdown of GLP-1 Receptors in Vagal Afferents Affects Normal Food Intake and Glycemia. Diabetes. 2016;65:34-43 pubmed 出版商

Nagaraja A, Dorniak P, Sadaoui N, Kang Y, Lin T, Armaiz Pena G, et al. Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis. Oncogene. 2016;35:2390-7 pubmed 出版商

Scala F, Brighenti E, Govoni M, Imbrogno E, Fornari F, Treré D, et al. Direct relationship between the level of p53 stabilization induced by rRNA synthesis-inhibiting drugs and the cell ribosome biogenesis rate. Oncogene. 2016;35:977-89 pubmed 出版商

Deschemin J, Allouche S, Brouillard F, Vaulont S. Iron Homeostasis and Inflammatory Status in Mice Deficient for the Cystic Fibrosis Transmembrane Regulator. PLoS ONE. 2015;10:e0145685 pubmed 出版商

Zhou N, Wang H, Liu H, Xue H, Lin F, Meng X, et al. MTA1-upregulated EpCAM is associated with metastatic behaviors and poor prognosis in lung cancer. J Exp Clin Cancer Res. 2015;34:157 pubmed 出版商

Sifford J, Stahl J, Salinas E, Forrest J. Murine Gammaherpesvirus 68 LANA and SOX Homologs Counteract ATM-Driven p53 Activity during Lytic Viral Replication. J Virol. 2015;90:2571-85 pubmed 出版商

Arrabal S, Lucena M, Canduela M, Ramos Uriarte A, Rivera P, Serrano A, et al. Pharmacological Blockade of Cannabinoid CB1 Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle. PLoS ONE. 2015;10:e0145244 pubmed 出版商

Engmann O, Giralt A, Gervasi N, Marion Poll L, Gasmi L, Filhol O, et al. DARPP-32 interaction with adducin may mediate rapid environmental effects on striatal neurons. Nat Commun. 2015;6:10099 pubmed 出版商

Anderson J, Ramadori G, Ioris R, Galiè M, Berglund E, Coate K, et al. Enhanced insulin sensitivity in skeletal muscle and liver by physiological overexpression of SIRT6. Mol Metab. 2015;4:846-56 pubmed 出版商

Abd Aziz N, Stanbridge E, Shafee N. Bortezomib attenuates HIF-1- but not HIF-2-mediated transcriptional activation. Oncol Lett. 2015;10:2192-2196 pubmed

Garcia Esparcia P, Hernández Ortega K, Koneti A, Gil L, Delgado Morales R, Castaño E, et al. Altered machinery of protein synthesis is region- and stage-dependent and is associated with α-synuclein oligomers in Parkinson's disease. Acta Neuropathol Commun. 2015;3:76 pubmed 出版商

Stepniak B, Kästner A, Poggi G, Mitjans M, Begemann M, Hartmann A, et al. Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes. EMBO Mol Med. 2015;7:1565-79 pubmed 出版商

Islam M, Smith D, Niu W, Fang S, Iqbal N, Sun G, et al. Enhancer Analysis Unveils Genetic Interactions between TLX and SOX2 in Neural Stem Cells and In Vivo Reprogramming. Stem Cell Reports. 2015;5:805-15 pubmed

Pan Y, Wang B, Yang X, Bai F, Xu Q, Li X, et al. CUL4A facilitates hepatocarcinogenesis by promoting cell cycle progression and epithelial-mesenchymal transition. Sci Rep. 2015;5:17006 pubmed 出版商

Quiñones M, Folgueira C, Sánchez Rebordelo E, Al Massadi O. Circulating Irisin Levels Are Not Regulated by Nutritional Status, Obesity, or Leptin Levels in Rodents. Mediators Inflamm. 2015;2015:620919 pubmed 出版商

Tachibana K, Haghparast S, Miyake J. Inhibition of cell adhesion by phosphorylated Ezrin/Radixin/Moesin. Cell Adh Migr. 2015;9:502-12 pubmed 出版商

Zhuang T, Zhu J, Li Z, Lorent J, Zhao C, Dahlman Wright K, et al. p21-activated kinase group II small compound inhibitor GNE-2861 perturbs estrogen receptor alpha signaling and restores tamoxifen-sensitivity in breast cancer cells. Oncotarget. 2015;6:43853-68 pubmed 出版商

Chen P, Chen H, Acharya D, Rando O, Fazzio T. R loops regulate promoter-proximal chromatin architecture and cellular differentiation. Nat Struct Mol Biol. 2015;22:999-1007 pubmed 出版商

Kropp J, Roti Roti E, Ringelstetter A, Khatib H, Abbott D, Salih S. Dexrazoxane Diminishes Doxorubicin-Induced Acute Ovarian Damage and Preserves Ovarian Function and Fecundity in Mice. PLoS ONE. 2015;10:e0142588 pubmed 出版商

Bejaoui M, Pantazi E, Folch Puy E, Panisello A, Calvo M, Pasut G, et al. Protective Effect of Intravenous High Molecular Weight Polyethylene Glycol on Fatty Liver Preservation. Biomed Res Int. 2015;2015:794287 pubmed 出版商

Wang J, Jiang Z, Lam W, Gullen E, Yu Z, Wei Y, et al. Study of Malformin C, a Fungal Source Cyclic Pentapeptide, as an Anti-Cancer Drug. PLoS ONE. 2015;10:e0140069 pubmed 出版商

DaMata J, Mendes B, Maciel Lima K, Menezes C, Dutra W, Sousa L, et al. Distinct Macrophage Fates after in vitro Infection with Different Species of Leishmania: Induction of Apoptosis by Leishmania (Leishmania) amazonensis, but Not by Leishmania (Viannia) guyanensis. PLoS ONE. 2015;10:e0141196 pubmed 出版商

Vishwamitra D, Curry C, Shi P, Alkan S, Amin H. SUMOylation Confers Posttranslational Stability on NPM-ALK Oncogenic Protein. Neoplasia. 2015;17:742-754 pubmed 出版商

Mazzacurati L, Lambert Q, Pradhan A, Griner L, Huszar D, Reuther G. The PIM inhibitor AZD1208 synergizes with ruxolitinib to induce apoptosis of ruxolitinib sensitive and resistant JAK2-V617F-driven cells and inhibit colony formation of primary MPN cells. Oncotarget. 2015;6:40141-57 pubmed 出版商

Guo W, Zhang Y, Ling Z, Liu X, Zhao X, Yuan Z, et al. Caspase-3 feedback loop enhances Bid-induced AIF/endoG and Bak activation in Bax and p53-independent manner. Cell Death Dis. 2015;6:e1919 pubmed 出版商

Woods N, Trevino J, Coppola D, Chellappan S, Yang S, Padmanabhan J. Fendiline inhibits proliferation and invasion of pancreatic cancer cells by interfering with ADAM10 activation and β-catenin signaling. Oncotarget. 2015;6:35931-48 pubmed 出版商

Carter B, Mak P, Mak D, Ruvolo V, Schober W, McQueen T, et al. Synergistic effects of p53 activation via MDM2 inhibition in combination with inhibition of Bcl-2 or Bcr-Abl in CD34+ proliferating and quiescent chronic myeloid leukemia blast crisis cells. Oncotarget. 2015;6:30487-99 pubmed 出版商

Cheishvili D, Stefanska B, Yi C, Li C, Yu P, Arakelian A, et al. A common promoter hypomethylation signature in invasive breast, liver and prostate cancer cell lines reveals novel targets involved in cancer invasiveness. Oncotarget. 2015;6:33253-68 pubmed 出版商

Cingaram P, Nyeste A, Dondapati D, Fodor E, Welker E. Prion Protein Does Not Confer Resistance to Hippocampus-Derived Zpl Cells against the Toxic Effects of Cu2+, Mn2+, Zn2+ and Co2+ Not Supporting a General Protective Role for PrP in Transition Metal Induced Toxicity. PLoS ONE. 2015;10:e0139219 pubmed 出版商

Shen S, Guo M, Xiong Z, Yu Y, Zhao X, Zhang F, et al. AIF inhibits tumor metastasis by protecting PTEN from oxidation. EMBO Rep. 2015;16:1563-80 pubmed 出版商

Keatinge M, Bui H, Menke A, Chen Y, Sokol A, Bai Q, et al. Glucocerebrosidase 1 deficient Danio rerio mirror key pathological aspects of human Gaucher disease and provide evidence of early microglial activation preceding alpha-synuclein-independent neuronal cell death. Hum Mol Genet. 2015;24:6640-52 pubmed 出版商

Rastetter R, Blömacher M, Drebber U, Marko M, Behrens J, Solga R, et al. Coronin 2A (CRN5) expression is associated with colorectal adenoma-adenocarcinoma sequence and oncogenic signalling. BMC Cancer. 2015;15:638 pubmed 出版商

Sasaki N, Itakura Y, Toyoda M. Ganglioside GM1 Contributes to the State of Insulin Resistance in Senescent Human Arterial Endothelial Cells. J Biol Chem. 2015;290:25475-86 pubmed 出版商

Barrett H, Kubala M, Scholz Romero K, Denny K, Woodruff T, McIntyre H, et al. Placental lipase expression in pregnancies complicated by preeclampsia: a case-control study. Reprod Biol Endocrinol. 2015;13:100 pubmed 出版商

Moussa R, Kovacevic Z, Richardson D. Differential targeting of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by chelators with anti-proliferative activity in a range of tumor cell-types. Oncotarget. 2015;6:29694-711 pubmed 出版商

Wong T, Lin S, Leung L. The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic Cells. PLoS ONE. 2015;10:e0135637 pubmed 出版商

Van Rossom S, Op de Beeck K, Hristovska V, Winderickx J, Van Camp G. The deafness gene DFNA5 induces programmed cell death through mitochondria and MAPK-related pathways. Front Cell Neurosci. 2015;9:231 pubmed 出版商

Bejaoui M, Pantazi E, De Luca V, Panisello A, Folch Puy E, Hotter G, et al. Carbonic Anhydrase Protects Fatty Liver Grafts against Ischemic Reperfusion Damage. PLoS ONE. 2015;10:e0134499 pubmed 出版商

Kim N, Gumbiner B. Adhesion to fibronectin regulates Hippo signaling via the FAK-Src-PI3K pathway. J Cell Biol. 2015;210:503-15 pubmed 出版商

Tsuneki M, Nakamura Y, Kinjo T, Nakanishi R, Arakawa H. Mieap suppresses murine intestinal tumor via its mitochondrial quality control. Sci Rep. 2015;5:12472 pubmed 出版商

Gee F, Rushton M, Loughlin J, Reynard L. Correlation of the osteoarthritis susceptibility variants that map to chromosome 20q13 with an expression quantitative trait locus operating on NCOA3 and with functional variation at the polymorphism rs116855380. Arthritis Rheumatol. 2015;67:2923-32 pubmed 出版商

Pencik J, Schlederer M, Gruber W, Unger C, Walker S, Chalaris A, et al. STAT3 regulated ARF expression suppresses prostate cancer metastasis. Nat Commun. 2015;6:7736 pubmed 出版商

Murakami N, Kühnel A, Schmid T, Ilicic K, Stangl S, Braun I, et al. Role of membrane Hsp70 in radiation sensitivity of tumor cells. Radiat Oncol. 2015;10:149 pubmed 出版商

Alaa El Din F, Patri S, Thoreau V, Rodríguez Ballesteros M, Hamade E, Bailly S, et al. Functional and splicing defect analysis of 23 ACVRL1 mutations in a cohort of patients affected by Hereditary Hemorrhagic Telangiectasia. PLoS ONE. 2015;10:e0132111 pubmed 出版商

Pei G, Schnettger L, Bronietzki M, Repnik U, Griffiths G, Gutierrez M. Interferon-γ-inducible Rab20 regulates endosomal morphology and EGFR degradation in macrophages. Mol Biol Cell. 2015;26:3061-70 pubmed 出版商

Moon J, Hisata S, Park M, DeNicola G, Ryter S, Nakahira K, et al. mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation. Cell Rep. 2015;12:102-115 pubmed 出版商

Campbell G, Rawat P, Bruckman R, Spector S. Human Immunodeficiency Virus Type 1 Nef Inhibits Autophagy through Transcription Factor EB Sequestration. PLoS Pathog. 2015;11:e1005018 pubmed 出版商

Radomska H, Jernigan F, Nakayama S, Jorge S, Sun L, Tenen D, et al. A Cell-Based High-Throughput Screening for Inducers of Myeloid Differentiation. J Biomol Screen. 2015;20:1150-9 pubmed 出版商

Dittmar M, Petermichl W, Lindner R, Sinner B, Graf B, Schlachetzki F, et al. In Vitro Induction of Endothelial Apoptosis of the Post-Hypoxic Blood-Brain Barrier by Isoflurane but Not by Sevoflurane and Midazolam. PLoS ONE. 2015;10:e0130408 pubmed 出版商

Chavez L, Calvanese V, Verdin E. HIV Latency Is Established Directly and Early in Both Resting and Activated Primary CD4 T Cells. PLoS Pathog. 2015;11:e1004955 pubmed 出版商

Li X, Jiang J, Yang R, Xu X, Hu F, Liu A, et al. Expression of HAX-1 in colorectal cancer and its role in cancer cell growth. Mol Med Rep. 2015;12:4071-4078 pubmed 出版商

Jennings C, Murer B, O Grady A, Hearn L, Harvey B, Kay E, et al. Differential p16/INK4A cyclin-dependent kinase inhibitor expression correlates with chemotherapy efficacy in a cohort of 88 malignant pleural mesothelioma patients. Br J Cancer. 2015;113:69-75 pubmed 出版商

Pappas S, Darr K, Holley S, Cepeda C, Mabrouk O, Wong J, et al. Forebrain deletion of the dystonia protein torsinA causes dystonic-like movements and loss of striatal cholinergic neurons. elife. 2015;4:e08352 pubmed 出版商

Escuin S, Vernay B, Savery D, Gurniak C, Witke W, Greene N, et al. Rho-kinase-dependent actin turnover and actomyosin disassembly are necessary for mouse spinal neural tube closure. J Cell Sci. 2015;128:2468-81 pubmed 出版商

Andrade L. Evidence for changes in beta- and gamma-actin proportions during inner ear hair cell life. Cytoskeleton (Hoboken). 2015;72:282-91 pubmed 出版商

Siegert S, Seo J, Kwon E, Rudenko A, Cho S, Wang W, et al. The schizophrenia risk gene product miR-137 alters presynaptic plasticity. Nat Neurosci. 2015;18:1008-16 pubmed 出版商

Toblli J, Cao G, Angerosa M. Ferrous sulfate, but not iron polymaltose complex, aggravates local and systemic inflammation and oxidative stress in dextran sodium sulfate-induced colitis in rats. Drug Des Devel Ther. 2015;9:2585-97 pubmed 出版商

Boucas J, Fritz C, Schmitt A, Riabinska A, Thelen L, Peifer M, et al. Label-Free Protein-RNA Interactome Analysis Identifies Khsrp Signaling Downstream of the p38/Mk2 Kinase Complex as a Critical Modulator of Cell Cycle Progression. PLoS ONE. 2015;10:e0125745 pubmed 出版商

Wang J, Guo W, Zhou H, Luo N, Nie C, Zhao X, et al. Mitochondrial p53 phosphorylation induces Bak-mediated and caspase-independent cell death. Oncotarget. 2015;6:17192-205 pubmed

Wang ondu R, Teal S, Park R, Heston L, Delecluse H, Miller G. DNA Damage Signaling Is Induced in the Absence of Epstein-Barr Virus (EBV) Lytic DNA Replication and in Response to Expression of ZEBRA. PLoS ONE. 2015;10:e0126088 pubmed 出版商

Raha Chowdhury R, Raha A, Forostyak S, Zhao J, Stott S, Bomford A. Expression and cellular localization of hepcidin mRNA and protein in normal rat brain. BMC Neurosci. 2015;16:24 pubmed 出版商

Dekker Nitert M, Scholz Romero K, Kubala M, McIntyre H, Callaway L, Barrett H. Placental fibroblast growth factor 21 is not altered in late-onset preeclampsia. Reprod Biol Endocrinol. 2015;13:14 pubmed 出版商

Wang S, Zhang J, Yang H, Wang F, Li S. Acupoint specificity on acupuncture regulation of hypothalamic- pituitary-adrenal cortex axis function. BMC Complement Altern Med. 2015;15:87 pubmed 出版商

Matsumoto M, Seike M, Noro R, Soeno C, Sugano T, Takeuchi S, et al. Control of the MYC-eIF4E axis plus mTOR inhibitor treatment in small cell lung cancer. BMC Cancer. 2015;15:241 pubmed 出版商

Kalfalah F, Berg E, Christensen M, Linka R, Dirks W, Boege F, et al. Spatio-temporal regulation of the human licensing factor Cdc6 in replication and mitosis. Cell Cycle. 2015;14:1704-15 pubmed 出版商

Moriya J, Ferrara N. Inhibition of protein kinase C enhances angiogenesis induced by platelet-derived growth factor C in hyperglycemic endothelial cells. Cardiovasc Diabetol. 2015;14:19 pubmed 出版商

Merlot A, Sahni S, Lane D, Fordham A, Pantarat N, Hibbs D, et al. Potentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cells. Oncotarget. 2015;6:10374-98 pubmed

Hirst A, Simms M, Mann V, Maitland N, O CONNELL D, Frame F. Low-temperature plasma treatment induces DNA damage leading to necrotic cell death in primary prostate epithelial cells. Br J Cancer. 2015;112:1536-45 pubmed 出版商

Isnard A, Christian J, Kodiha M, Stochaj U, McMaster W, Olivier M. Impact of Leishmania infection on host macrophage nuclear physiology and nucleopore complex integrity. PLoS Pathog. 2015;11:e1004776 pubmed 出版商

Xu H, Cho S, Bang M, Bae C, Choi Y, Li Y, et al. FK-3000 isolated from Stephania delavayi Diels. inhibits MDA-MB-231 cell proliferation by decreasing NF-κB phosphorylation and COX-2 expression. Int J Oncol. 2015;46:2309-16 pubmed 出版商

Komine K, Shimodaira H, Takao M, Soeda H, Zhang X, Takahashi M, et al. Functional Complementation Assay for 47 MUTYH Variants in a MutY-Disrupted Escherichia coli Strain. Hum Mutat. 2015;36:704-11 pubmed 出版商

Zhu T, Liu T, Shi Y, Zhao Q. Vitamin D/VDR signaling pathway ameliorates 2,4,6-trinitrobenzene sulfonic acid-induced colitis by inhibiting intestinal epithelial apoptosis. Int J Mol Med. 2015;35:1213-8 pubmed 出版商

Herrmann L, Wiegmann C, Arsalan Werner A, Hilbrich I, Jäger C, Flach K, et al. Hook proteins: association with Alzheimer pathology and regulatory role of hook3 in amyloid beta generation. PLoS ONE. 2015;10:e0119423 pubmed 出版商

Priolo C, Ricoult S, Khabibullin D, Filippakis H, Yu J, Manning B, et al. Tuberous sclerosis complex 2 loss increases lysophosphatidylcholine synthesis in lymphangioleiomyomatosis. Am J Respir Cell Mol Biol. 2015;53:33-41 pubmed 出版商

Debeb B, Smith D, Li L, Larson R, Xu W, Woodward W. Differential effect of phosphorylation-defective survivin on radiation response in estrogen receptor-positive and -negative breast cancer. PLoS ONE. 2015;10:e0120719 pubmed 出版商

Jahns H, Roos M, Imig J, Baumann F, Wang Y, Gilmour R, et al. Stereochemical bias introduced during RNA synthesis modulates the activity of phosphorothioate siRNAs. Nat Commun. 2015;6:6317 pubmed 出版商

Ito S, Araya J, Kurita Y, Kobayashi K, Takasaka N, Yoshida M, et al. PARK2-mediated mitophagy is involved in regulation of HBEC senescence in COPD pathogenesis. Autophagy. 2015;11:547-59 pubmed 出版商

Ulas M, Orhan C, Tuzcu M, Ozercan I, Sahin N, Gencoglu H, et al. Anti-diabetic potential of chromium histidinate in diabetic retinopathy rats. BMC Complement Altern Med. 2015;15:16 pubmed 出版商

Wamelink M, Ramos R, van den Elzen A, Ruijter G, Bonte R, Diogo L, et al. First two unrelated cases of isolated sedoheptulokinase deficiency: A benign disorder?. J Inherit Metab Dis. 2015;38:889-94 pubmed 出版商

Wei Y, Melas P, Wegener G, Mathé A, Lavebratt C. Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene. Int J Neuropsychopharmacol. 2014;18: pubmed 出版商

Wei Y, Backlund L, Wegener G, Mathé A, Lavebratt C. Telomerase dysregulation in the hippocampus of a rat model of depression: normalization by lithium. Int J Neuropsychopharmacol. 2015;18:pyv002 pubmed 出版商

Cécyre B, Monette M, Beudjekian L, Casanova C, Bouchard J. Localization of diacylglycerol lipase alpha and monoacylglycerol lipase during postnatal development of the rat retina. Front Neuroanat. 2014;8:150 pubmed 出版商

Blanco E, Pavón F, Palomino A, Luque Rojas M, Serrano A, Rivera P, et al. Cocaine-induced behavioral sensitization is associated with changes in the expression of endocannabinoid and glutamatergic signaling systems in the mouse prefrontal cortex. Int J Neuropsychopharmacol. 2014;18: pubmed 出版商

Maskey R, Kim M, Baker D, Childs B, Malureanu L, Jeganathan K, et al. Spartan deficiency causes genomic instability and progeroid phenotypes. Nat Commun. 2014;5:5744 pubmed 出版商

Heckler M, Riggins R. ERRβ splice variants differentially regulate cell cycle progression. Cell Cycle. 2015;14:31-45 pubmed 出版商

Wang Q, Xiao B, Cui S, Song H, Qian Y, Dong L, et al. Triptolide treatment reduces Alzheimer's disease (AD)-like pathology through inhibition of BACE1 in a transgenic mouse model of AD. Dis Model Mech. 2014;7:1385-95 pubmed 出版商

Sunaga D, Tanno M, Kuno A, Ishikawa S, Ogasawara M, Yano T, et al. Accelerated recovery of mitochondrial membrane potential by GSK-3β inactivation affords cardiomyocytes protection from oxidant-induced necrosis. PLoS ONE. 2014;9:e112529 pubmed 出版商

Li Y, Kim B, Cho S, Bang M, Kim S, Park D. 6,7-di-O-acetylsinococuline (FK-3000) induces G2/M phase arrest in breast carcinomas through p38 MAPK phosphorylation and CDC25B dephosphorylation. Int J Oncol. 2015;46:578-86 pubmed 出版商

Lee Y, Ehninger D, Zhou M, Oh J, Kang M, Kwak C, et al. Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndrome. Nat Neurosci. 2014;17:1736-43 pubmed 出版商

Roos M, Rebhan M, Lucic M, Pavlicek D, Pradère U, Towbin H, et al. Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells. Nucleic Acids Res. 2015;43:e9 pubmed 出版商

Gonen Korkmaz C, Sevin G, Gokce G, Arun M, Yildirim G, Reel B, et al. Analysis of tumor necrosis factor α-induced and nuclear factor κB-silenced LNCaP prostate cancer cells by RT-qPCR. Exp Ther Med. 2014;8:1695-1700 pubmed

Nie C, Luo Y, Zhao X, Luo N, Tong A, Liu X, et al. Caspase-9 mediates Puma activation in UCN-01-induced apoptosis. Cell Death Dis. 2014;5:e1495 pubmed 出版商

Martino Echarri E, Henderson B, Brocardo M. Targeting the DNA replication checkpoint by pharmacologic inhibition of Chk1 kinase: a strategy to sensitize APC mutant colon cancer cells to 5-fluorouracil chemotherapy. Oncotarget. 2014;5:9889-900 pubmed

Hassanpour S, Jiang H, Wang Y, Kuiper J, Glogauer M. The actin binding protein adseverin regulates osteoclastogenesis. PLoS ONE. 2014;9:e109078 pubmed 出版商

Ross M, Borazjani A, Mangum L, Wang R, Crow J. Effects of toxicologically relevant xenobiotics and the lipid-derived electrophile 4-hydroxynonenal on macrophage cholesterol efflux: silencing carboxylesterase 1 has paradoxical effects on cholesterol uptake and efflux. Chem Res Toxicol. 2014;27:1743-56 pubmed 出版商

Wu X, Renuse S, Sahasrabuddhe N, Zahari M, Chaerkady R, Kim M, et al. Activation of diverse signalling pathways by oncogenic PIK3CA mutations. Nat Commun. 2014;5:4961 pubmed 出版商

Ghandhi S, Ponnaiya B, Panigrahi S, Hopkins K, Cui Q, Hei T, et al. RAD9 deficiency enhances radiation induced bystander DNA damage and transcriptomal response. Radiat Oncol. 2014;9:206 pubmed 出版商

Makhlouf M, Ouimette J, Oldfield A, Navarro P, Neuillet D, Rougeulle C. A prominent and conserved role for YY1 in Xist transcriptional activation. Nat Commun. 2014;5:4878 pubmed 出版商

Widera M, Hillebrand F, Erkelenz S, Vasudevan A, Münk C, Schaal H. A functional conserved intronic G run in HIV-1 intron 3 is critical to counteract APOBEC3G-mediated host restriction. Retrovirology. 2014;11:72 pubmed 出版商

Lima V, Lobato N, Filgueira F, Webb R, Tostes R, Giachini F. Vascular O-GlcNAcylation augments reactivity to constrictor stimuli by prolonging phosphorylated levels of the myosin light chain. Braz J Med Biol Res. 2014;47:826-33 pubmed

Llorens F, Lopez Gonzalez I, Thune K, Carmona M, Zafar S, Andreoletti O, et al. Subtype and regional-specific neuroinflammation in sporadic creutzfeldt-jakob disease. Front Aging Neurosci. 2014;6:198 pubmed 出版商

Shi H, Fu C, Wang W, Li Y, Du S, Cao R, et al. The FGF-1-specific single-chain antibody scFv1C9 effectively inhibits breast cancer tumour growth and metastasis. J Cell Mol Med. 2014;18:2061-70 pubmed 出版商

Barrett H, Kubala M, Scholz Romero K, Denny K, Woodruff T, McIntyre H, et al. Placental lipases in pregnancies complicated by gestational diabetes mellitus (GDM). PLoS ONE. 2014;9:e104826 pubmed 出版商

Li S, Li Z, Shu F, Xiong H, Phillips A, Dynan W. Double-strand break repair deficiency in NONO knockout murine embryonic fibroblasts and compensation by spontaneous upregulation of the PSPC1 paralog. Nucleic Acids Res. 2014;42:9771-80 pubmed 出版商

Fukumoto M, Amanuma T, Kuwahara Y, Shimura T, Suzuki M, Mori S, et al. Guanine nucleotide-binding protein 1 is one of the key molecules contributing to cancer cell radioresistance. Cancer Sci. 2014;105:1351-9 pubmed 出版商

Wolfe A, Singh K, Zhong Y, Drewe P, Rajasekhar V, Sanghvi V, et al. RNA G-quadruplexes cause eIF4A-dependent oncogene translation in cancer. Nature. 2014;513:65-70 pubmed 出版商

Kovarova M, Koller B. PGE? promotes apoptosis induced by cytokine deprivation through EP3 receptor and induces Bim in mouse mast cells. PLoS ONE. 2014;9:e102948 pubmed 出版商

Huth L, Rose M, Kloubert V, Winkens W, Schlensog M, Hartmann A, et al. BDNF is associated with SFRP1 expression in luminal and basal-like breast cancer cell lines and primary breast cancer tissues: a novel role in tumor suppression?. PLoS ONE. 2014;9:e102558 pubmed 出版商

Boname J, Bloor S, Wandel M, Nathan J, Antrobus R, Dingwell K, et al. Cleavage by signal peptide peptidase is required for the degradation of selected tail-anchored proteins. J Cell Biol. 2014;205:847-62 pubmed 出版商

Deplus R, Denis H, Putmans P, Calonne E, Fourrez M, Yamamoto K, et al. Citrullination of DNMT3A by PADI4 regulates its stability and controls DNA methylation. Nucleic Acids Res. 2014;42:8285-96 pubmed 出版商

Edagawa M, Kawauchi J, Hirata M, Goshima H, Inoue M, Okamoto T, et al. Role of activating transcription factor 3 (ATF3) in endoplasmic reticulum (ER) stress-induced sensitization of p53-deficient human colon cancer cells to tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL)-mediated apoptosis through . J Biol Chem. 2014;289:21544-61 pubmed 出版商

Kagawa S, Natsuizaka M, Whelan K, Facompre N, Naganuma S, Ohashi S, et al. Cellular senescence checkpoint function determines differential Notch1-dependent oncogenic and tumor-suppressor activities. Oncogene. 2015;34:2347-59 pubmed 出版商

Sarr O, Thompson J, Zhao L, Lee T, Regnault T. Low birth weight male guinea pig offspring display increased visceral adiposity in early adulthood. PLoS ONE. 2014;9:e98433 pubmed 出版商

Yoshikawa Y, Sato A, Tsujimura T, Otsuki T, Fukuoka K, Hasegawa S, et al. Biallelic germline and somatic mutations in malignant mesothelioma: multiple mutations in transcription regulators including mSWI/SNF genes. Int J Cancer. 2015;136:560-71 pubmed 出版商

Yarham J, Lamichhane T, Pyle A, Mattijssen S, Baruffini E, Bruni F, et al. Defective i6A37 modification of mitochondrial and cytosolic tRNAs results from pathogenic mutations in TRIT1 and its substrate tRNA. PLoS Genet. 2014;10:e1004424 pubmed 出版商

Galiger C, Kostin S, Golec A, Ahlbrecht K, Becker S, Gherghiceanu M, et al. Phenotypical and ultrastructural features of Oct4-positive cells in the adult mouse lung. J Cell Mol Med. 2014;18:1321-33 pubmed 出版商

Brinkman A, Wu J, Ersland K, Xu W. Estrogen receptor ? and aryl hydrocarbon receptor independent growth inhibitory effects of aminoflavone in breast cancer cells. BMC Cancer. 2014;14:344 pubmed 出版商

Schreml S, Meier R, Kirschbaum M, Kong S, Gehmert S, Felthaus O, et al. Luminescent dual sensors reveal extracellular pH-gradients and hypoxia on chronic wounds that disrupt epidermal repair. Theranostics. 2014;4:721-35 pubmed 出版商

Caito S, Zeng H, Aschner J, Aschner M. Methylmercury alters the activities of Hsp90 client proteins, prostaglandin E synthase/p23 (PGES/23) and nNOS. PLoS ONE. 2014;9:e98161 pubmed 出版商

Magi S, Saeki Y, Kasamatsu M, Tashiro E, Imoto M. Chemical genomic-based pathway analyses for epidermal growth factor-mediated signaling in migrating cancer cells. PLoS ONE. 2014;9:e96776 pubmed 出版商

De Leonardis F, Monti L, Gualeni B, Tenni R, Forlino A, Rossi A. Altered signaling in the G1 phase deregulates chondrocyte growth in a mouse model with proteoglycan undersulfation. J Cell Biochem. 2014;115:1779-86 pubmed 出版商

Shaw Hallgren G, Chmielarska Masoumi K, Zarrizi R, Hellman U, Karlsson P, Helou K, et al. Association of nuclear-localized Nemo-like kinase with heat-shock protein 27 inhibits apoptosis in human breast cancer cells. PLoS ONE. 2014;9:e96506 pubmed 出版商

Frost G, Sleeth M, Sahuri Arisoylu M, Lizarbe B, Cerdan S, Brody L, et al. The short-chain fatty acid acetate reduces appetite via a central homeostatic mechanism. Nat Commun. 2014;5:3611 pubmed 出版商

Wang S, Zhang J, Qie L. Acupuncture Relieves the Excessive Excitation of Hypothalamic-Pituitary-Adrenal Cortex Axis Function and Correlates with the Regulatory Mechanism of GR, CRH, and ACTHR. Evid Based Complement Alternat Med. 2014;2014:495379 pubmed 出版商

Vose L, Vinukonda G, Diamond D, Korumilli R, Hu F, Zia M, et al. Prenatal betamethasone does not affect glutamatergic or GABAergic neurogenesis in preterm newborns. Neuroscience. 2014;270:148-57 pubmed 出版商

Gapp K, Jawaid A, Sarkies P, Bohacek J, Pelczar P, Prados J, et al. Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice. Nat Neurosci. 2014;17:667-9 pubmed 出版商

Genís L, Dávila D, Fernandez S, Pozo Rodrigálvarez A, Martínez Murillo R, Torres Aleman I. Astrocytes require insulin-like growth factor I to protect neurons against oxidative injury. F1000Res. 2014;3:28 pubmed 出版商

Nakamura I, Zakharia K, Banini B, Mikhail D, Kim T, Yang J, et al. Brivanib attenuates hepatic fibrosis in vivo and stellate cell activation in vitro by inhibition of FGF, VEGF and PDGF signaling. PLoS ONE. 2014;9:e92273 pubmed 出版商

Park R, El Guindy A, Heston L, Lin S, Yu K, Nagy M, et al. Nuclear translocation and regulation of intranuclear distribution of cytoplasmic poly(A)-binding protein are distinct processes mediated by two Epstein Barr virus proteins. PLoS ONE. 2014;9:e92593 pubmed 出版商

Yang L, Gilbert M, Zheng R, McKnight G. Selective expression of a dominant-negative type I? PKA regulatory subunit in striatal medium spiny neurons impairs gene expression and leads to reduced feeding and locomotor activity. J Neurosci. 2014;34:4896-904 pubmed 出版商

Zhu Y, Zhou Y, Shi J. Post-slippage multinucleation renders cytotoxic variation in anti-mitotic drugs that target the microtubules or mitotic spindle. Cell Cycle. 2014;13:1756-64 pubmed 出版商

Lin D, Hao J, Nagata Y, Xu L, Shang L, Meng X, et al. Genomic and molecular characterization of esophageal squamous cell carcinoma. Nat Genet. 2014;46:467-73 pubmed 出版商

Huang Y, Liu H, Li S, Tang Y, Wei B, Yu H, et al. MAVS-MKK7-JNK2 defines a novel apoptotic signaling pathway during viral infection. PLoS Pathog. 2014;10:e1004020 pubmed 出版商

Susa T, Sawai N, Aoki T, Iizuka Kogo A, Kogo H, Negishi A, et al. Effects of repeated administration of pilocarpine and isoproterenol on aquaporin-5 expression in rat salivary glands. Acta Histochem Cytochem. 2013;46:187-97 pubmed 出版商

Wongtrakoongate P, Li J, Andrews P. Aza-deoxycytidine induces apoptosis or differentiation via DNMT3B and targets embryonal carcinoma cells but not their differentiated derivatives. Br J Cancer. 2014;110:2131-8 pubmed 出版商

Zhang X, Fryknäs M, Hernlund E, Fayad W, De Milito A, Olofsson M, et al. Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments. Nat Commun. 2014;5:3295 pubmed 出版商

Liu H, Yang J, Yuan Y, Xia Z, Chen M, Xie L, et al. Regulation of Mcl-1 by constitutive activation of NF-?B contributes to cell viability in human esophageal squamous cell carcinoma cells. BMC Cancer. 2014;14:98 pubmed 出版商

Karlsson A, Washington J, Dimitrova V, Hooper C, Shekhtman A, Bakowska J. The role of spartin and its novel ubiquitin binding region in DALIS occurrence. Mol Biol Cell. 2014;25:1355-65 pubmed 出版商

Jung C, Lee M, Kang Y, Lee Y, Yoon H, Kang S, et al. Vaspin inhibits cytokine-induced nuclear factor-kappa B activation and adhesion molecule expression via AMP-activated protein kinase activation in vascular endothelial cells. Cardiovasc Diabetol. 2014;13:41 pubmed 出版商

Musharraf A, Kruspe D, Tomasch J, Besenbeck B, Englert C, Landgraf K. BOR-syndrome-associated Eya1 mutations lead to enhanced proteasomal degradation of Eya1 protein. PLoS ONE. 2014;9:e87407 pubmed 出版商

Ratnayake M, Plöger F, Santibanez Koref M, Loughlin J. Human chondrocytes respond discordantly to the protein encoded by the osteoarthritis susceptibility gene GDF5. PLoS ONE. 2014;9:e86590 pubmed 出版商

Sullivan K, QUINN K, Tang K, Georgakoudi I, Black L. Extracellular matrix remodeling following myocardial infarction influences the therapeutic potential of mesenchymal stem cells. Stem Cell Res Ther. 2014;5:14 pubmed 出版商

Hagelkruys A, Lagger S, Krahmer J, Leopoldi A, Artaker M, Pusch O, et al. A single allele of Hdac2 but not Hdac1 is sufficient for normal mouse brain development in the absence of its paralog. Development. 2014;141:604-616 pubmed 出版商

Zhang B, Chen J, Cheng A, Ko B. Depletion of sirtuin 1 (SIRT1) leads to epigenetic modifications of telomerase (TERT) gene in hepatocellular carcinoma cells. PLoS ONE. 2014;9:e84931 pubmed 出版商

Rutnam Z, Du W, Yang W, Yang X, Yang B. The pseudogene TUSC2P promotes TUSC2 function by binding multiple microRNAs. Nat Commun. 2014;5:2914 pubmed 出版商

Li X, Chen W, Zhang L, Liu W, Fei Z. Inhibition of store-operated calcium entry attenuates MPP(+)-induced oxidative stress via preservation of mitochondrial function in PC12 cells: involvement of Homer1a. PLoS ONE. 2013;8:e83638 pubmed 出版商

Tanaka T, Kai S, Matsuyama T, Adachi T, Fukuda K, Hirota K. General anesthetics inhibit LPS-induced IL-1? expression in glial cells. PLoS ONE. 2013;8:e82930 pubmed 出版商

Benz A, Renne C, Maronde E, Koch M, Grabiec U, Kallendrusch S, et al. Expression and functional relevance of cannabinoid receptor 1 in Hodgkin lymphoma. PLoS ONE. 2013;8:e81675 pubmed 出版商

Duquette M, Sadow P, Lawler J, Nucera C. Thrombospondin-1 Silencing Down-Regulates Integrin Expression Levels in Human Anaplastic Thyroid Cancer Cells with BRAF(V600E): New Insights in the Host Tissue Adaptation and Homeostasis of Tumor Microenvironment. Front Endocrinol (Lausanne). 2013;4:189 pubmed 出版商

Fiaschetti G, Abela L, Nonoguchi N, Dubuc A, Remke M, Boro A, et al. Epigenetic silencing of miRNA-9 is associated with HES1 oncogenic activity and poor prognosis of medulloblastoma. Br J Cancer. 2014;110:636-47 pubmed 出版商

Senín L, Al Massadi O, Folgueira C, Castelao C, Pardo M, Barja Fernandez S, et al. The gastric CB1 receptor modulates ghrelin production through the mTOR pathway to regulate food intake. PLoS ONE. 2013;8:e80339 pubmed 出版商

Chen P, Hung J, Hickman T, Coles A, Carey J, Weng Z, et al. Hdac6 regulates Tip60-p400 function in stem cells. elife. 2013;2:e01557 pubmed 出版商

Raha A, VAISHNAV R, FRIEDLAND R, Bomford A, Raha Chowdhury R. The systemic iron-regulatory proteins hepcidin and ferroportin are reduced in the brain in Alzheimer's disease. Acta Neuropathol Commun. 2013;1:55 pubmed 出版商

Turner B, Alfazema N, Sheean R, Sleigh J, Davies K, Horne M, et al. Overexpression of survival motor neuron improves neuromuscular function and motor neuron survival in mutant SOD1 mice. Neurobiol Aging. 2014;35:906-15 pubmed 出版商

Chan J, Bhattacharyya D, Lassen K, Ruelas D, Greene W. Calcium/calcineurin synergizes with prostratin to promote NF-?B dependent activation of latent HIV. PLoS ONE. 2013;8:e77749 pubmed 出版商

Schupp M, Chen F, Briggs E, Rao S, Pelzmann H, Pessentheiner A, et al. Metabolite and transcriptome analysis during fasting suggest a role for the p53-Ddit4 axis in major metabolic tissues. BMC Genomics. 2013;14:758 pubmed 出版商

Dong L, Chen J, Li F, Gao F, Wu J, Miao Y, et al. Enhanced expression of NR2B subunits of NMDA receptors in the inherited glaucomatous DBA/2J mouse retina. Neural Plast. 2013;2013:670254 pubmed 出版商

Forrester A, Elias M, Woodward E, Graham M, Williams F, Reynolds N. Induction of a chloracne phenotype in an epidermal equivalent model by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) is dependent on aryl hydrocarbon receptor activation and is not reproduced by aryl hydrocarbon receptor knock down. J Dermatol Sci. 2014;73:10-22 pubmed 出版商

Suarez J, Rivera P, Arrabal S, Crespillo A, Serrano A, Baixeras E, et al. Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat. Dis Model Mech. 2014;7:129-41 pubmed 出版商

Evans C, Cook S, Coleman M, Gilley J. MEK inhibitor U0126 reverses protection of axons from Wallerian degeneration independently of MEK-ERK signaling. PLoS ONE. 2013;8:e76505 pubmed 出版商

Jang B, Choi B, Kim J, Kim M, Sohn M, Suh S. Impairment of autophagic flux promotes glucose reperfusion-induced neuro2A cell death after glucose deprivation. PLoS ONE. 2013;8:e76466 pubmed 出版商

Tran S, Wang Y, Lamba P, Zhou X, Boehm U, Bernard D. The CpG island in the murine foxl2 proximal promoter is differentially methylated in primary and immortalized cells. PLoS ONE. 2013;8:e76642 pubmed 出版商

Turcan S, Fabius A, Borodovsky A, Pedraza A, Brennan C, Huse J, et al. Efficient induction of differentiation and growth inhibition in IDH1 mutant glioma cells by the DNMT Inhibitor Decitabine. Oncotarget. 2013;4:1729-36 pubmed

Karimian Azari E, Leitner C, Jaggi T, Langhans W, Mansouri A. Possible role of intestinal fatty acid oxidation in the eating-inhibitory effect of the PPAR-? agonist Wy-14643 in high-fat diet fed rats. PLoS ONE. 2013;8:e74869 pubmed 出版商

Daino K, Imaoka T, Morioka T, Tani S, Iizuka D, Nishimura M, et al. Loss of the BRCA1-interacting helicase BRIP1 results in abnormal mammary acinar morphogenesis. PLoS ONE. 2013;8:e74013 pubmed 出版商

Epple L, Dodd R, Merz A, Dechkovskaia A, Herring M, Winston B, et al. Induction of the unfolded protein response drives enhanced metabolism and chemoresistance in glioma cells. PLoS ONE. 2013;8:e73267 pubmed 出版商

Gallaher A, Das S, Xiao Z, Andresson T, Kieffer Kwon P, Happel C, et al. Proteomic screening of human targets of viral microRNAs reveals functions associated with immune evasion and angiogenesis. PLoS Pathog. 2013;9:e1003584 pubmed 出版商

Yoshikawa T, Otsuka M, Kishikawa T, Takata A, Ohno M, Shibata C, et al. Unique haploinsufficient role of the microRNA-processing molecule Dicer1 in a murine colitis-associated tumorigenesis model. PLoS ONE. 2013;8:e71969 pubmed 出版商

Cong W, Wang R, Cai H, Daimon C, Scheibye Knudsen M, Bohr V, et al. Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice. PLoS ONE. 2013;8:e70257 pubmed 出版商

Ye L, Widlund A, Sims C, Lamming D, Guan Y, Davis J, et al. Rapamycin doses sufficient to extend lifespan do not compromise muscle mitochondrial content or endurance. Aging (Albany NY). 2013;5:539-50 pubmed

Iwaki J, Kikuchi K, Mizuguchi Y, Kawahigashi Y, Yoshida H, Uchida E, et al. MiR-376c down-regulation accelerates EGF-dependent migration by targeting GRB2 in the HuCCT1 human intrahepatic cholangiocarcinoma cell line. PLoS ONE. 2013;8:e69496 pubmed 出版商

Rapicavoli N, Qu K, Zhang J, Mikhail M, Laberge R, Chang H. A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics. elife. 2013;2:e00762 pubmed 出版商

Wall C, Lim R, Poljak M, Lappas M. Dietary flavonoids as therapeutics for preterm birth: luteolin and kaempferol suppress inflammation in human gestational tissues in vitro. Oxid Med Cell Longev. 2013;2013:485201 pubmed 出版商

Cheung V, Bouralexis S, Gillespie M. PTHrP Overexpression Increases Sensitivity of Breast Cancer Cells to Apo2L/TRAIL. PLoS ONE. 2013;8:e66343 pubmed 出版商

Chen X, Chen J, Gan S, Guan H, Zhou Y, Ouyang Q, et al. DNA damage strength modulates a bimodal switch of p53 dynamics for cell-fate control. BMC Biol. 2013;11:73 pubmed 出版商

Deng T, Zhu Z, Zhang S, Leng F, Cherukuri S, Hansen L, et al. HMGN1 modulates nucleosome occupancy and DNase I hypersensitivity at the CpG island promoters of embryonic stem cells. Mol Cell Biol. 2013;33:3377-89 pubmed 出版商

Xu Y, Yuan J, Lipinski M. Live imaging and single-cell analysis reveal differential dynamics of autophagy and apoptosis. Autophagy. 2013;9:1418-30 pubmed 出版商

Burguillos M, Magnusson C, Nordin M, Lenshof A, Augustsson P, Hansson M, et al. Microchannel acoustophoresis does not impact survival or function of microglia, leukocytes or tumor cells. PLoS ONE. 2013;8:e64233 pubmed 出版商

Korecka J, Van Kesteren R, Blaas E, Spitzer S, Kamstra J, Smit A, et al. Phenotypic characterization of retinoic acid differentiated SH-SY5Y cells by transcriptional profiling. PLoS ONE. 2013;8:e63862 pubmed 出版商

Feduska J, Garcia P, Brennan S, Bu S, Council L, Yoon K. N-glycosylation of ICAM-2 is required for ICAM-2-mediated complete suppression of metastatic potential of SK-N-AS neuroblastoma cells. BMC Cancer. 2013;13:261 pubmed 出版商

Zhu Y, Li H, Li K, Zhao X, An T, Hu X, et al. Necl-4/SynCAM-4 is expressed in myelinating oligodendrocytes but not required for axonal myelination. PLoS ONE. 2013;8:e64264 pubmed 出版商

de Sousa E, Walter L, Higa G, Casado O, Kihara A. Developmental and functional expression of miRNA-stability related genes in the nervous system. PLoS ONE. 2013;8:e56908 pubmed 出版商

Rak Mardyła A, Durak M, Lucja Gregoraszczuk E. Effects of resistin on porcine ovarian follicle steroidogenesis in prepubertal animals: an in vitro study. Reprod Biol Endocrinol. 2013;11:45 pubmed 出版商

Ulukaya E, Frame F, Cevatemre B, Pellacani D, Walker H, Mann V, et al. Differential cytotoxic activity of a novel palladium-based compound on prostate cell lines, primary prostate epithelial cells and prostate stem cells. PLoS ONE. 2013;8:e64278 pubmed 出版商

Lin Y, Jean Y, Lee H, Chen W, Sun Y, Su J, et al. A soft coral-derived compound, 11-epi-sinulariolide acetate suppresses inflammatory response and bone destruction in adjuvant-induced arthritis. PLoS ONE. 2013;8:e62926 pubmed 出版商

Smeets M, Chan A, Dagger S, Bradley C, Wei A, Izon D. Fli-1 overexpression in hematopoietic progenitors deregulates T cell development and induces pre-T cell lymphoblastic leukaemia/lymphoma. PLoS ONE. 2013;8:e62346 pubmed 出版商

Matak P, Zumerle S, Mastrogiannaki M, El Balkhi S, Delga S, Mathieu J, et al. Copper deficiency leads to anemia, duodenal hypoxia, upregulation of HIF-2? and altered expression of iron absorption genes in mice. PLoS ONE. 2013;8:e59538 pubmed 出版商

Innes C, Hesse J, Palii S, Helmink B, Holub A, Sleckman B, et al. DNA damage activates a complex transcriptional response in murine lymphocytes that includes both physiological and cancer-predisposition programs. BMC Genomics. 2013;14:163 pubmed 出版商

Feldman D, Chen C, Punj V, Machida K. The TBC1D15 oncoprotein controls stem cell self-renewal through destabilization of the Numb-p53 complex. PLoS ONE. 2013;8:e57312 pubmed 出版商

Shakibaei M, Mobasheri A, Lueders C, Büsch F, Shayan P, Goel A. Curcumin enhances the effect of chemotherapy against colorectal cancer cells by inhibition of NF-?B and Src protein kinase signaling pathways. PLoS ONE. 2013;8:e57218 pubmed 出版商

Xi X, Zhang X, Wang B, Wang T, Wang J, Huang H, et al. The interplays between autophagy and apoptosis induced by enterovirus 71. PLoS ONE. 2013;8:e56966 pubmed 出版商

Kempuraj D, Twait E, Williard D, Yuan Z, Meyerholz D, Samuel I. The novel cytokine interleukin-33 activates acinar cell proinflammatory pathways and induces acute pancreatic inflammation in mice. PLoS ONE. 2013;8:e56866 pubmed 出版商

Krishnan M, Lapierre L, Knowles B, Goldenring J. Rab25 regulates integrin expression in polarized colonic epithelial cells. Mol Biol Cell. 2013;24:818-31 pubmed 出版商

Pérez Sieira S, Martinez G, Porteiro B, Lopez M, Vidal A, Nogueiras R, et al. Female Nur77-deficient mice show increased susceptibility to diet-induced obesity. PLoS ONE. 2013;8:e53836 pubmed 出版商

Kilic U, Kilic E, Tuzcu Z, Tuzcu M, Ozercan I, Yilmaz O, et al. Melatonin suppresses cisplatin-induced nephrotoxicity via activation of Nrf-2/HO-1 pathway. Nutr Metab (Lond). 2013;10:7 pubmed 出版商

Bhat A, Andersen P, Qin Z, Xiao W. Rev3, the catalytic subunit of Pol?, is required for maintaining fragile site stability in human cells. Nucleic Acids Res. 2013;41:2328-39 pubmed 出版商

Imam J, Plyler J, Bansal H, Prajapati S, Bansal S, Rebeles J, et al. Genomic loss of tumor suppressor miRNA-204 promotes cancer cell migration and invasion by activating AKT/mTOR/Rac1 signaling and actin reorganization. PLoS ONE. 2012;7:e52397 pubmed 出版商

Gammoh N, Florey O, Overholtzer M, Jiang X. Interaction between FIP200 and ATG16L1 distinguishes ULK1 complex-dependent and -independent autophagy. Nat Struct Mol Biol. 2013;20:144-9 pubmed 出版商

Takaki J, Fujimori K, Miura M, Suzuki T, Sekino Y, Sato K. L-glutamate released from activated microglia downregulates astrocytic L-glutamate transporter expression in neuroinflammation: the 'collusion' hypothesis for increased extracellular L-glutamate concentration in neuroinflammation. J Neuroinflammation. 2012;9:275 pubmed 出版商

Cavallo F, Graziani G, Antinozzi C, Feldman D, Houldsworth J, Bosl G, et al. Reduced proficiency in homologous recombination underlies the high sensitivity of embryonal carcinoma testicular germ cell tumors to Cisplatin and poly (adp-ribose) polymerase inhibition. PLoS ONE. 2012;7:e51563 pubmed 出版商

Liu F, Sun Y, Xu Y, Liu F, Wang L, Zhao X. Expression and phosphorylation of stathmin correlate with cell migration in esophageal squamous cell carcinoma. Oncol Rep. 2013;29:419-24 pubmed 出版商

Steuble M, Diep T, Sch tzle P, Ludwig A, Tagaya M, Kunz B, et al. Calsyntenin-1 shelters APP from proteolytic processing during anterograde axonal transport. Biol Open. 2012;1:761-74 pubmed 出版商

Zheng X, Vittar N, Gai X, Fernández Barrena M, Moser C, Hu C, et al. The transcription factor GLI1 mediates TGF?1 driven EMT in hepatocellular carcinoma via a SNAI1-dependent mechanism. PLoS ONE. 2012;7:e49581 pubmed 出版商

Liu S, Chang S, Lee T, Chuang L, Guh J, Hung C, et al. Dioscorea alata attenuates renal interstitial cellular fibrosis by regulating Smad- and epithelial-mesenchymal transition signaling pathways. PLoS ONE. 2012;7:e47482 pubmed 出版商

Epaud R, Aubey F, Xu J, Chaker Z, Clemessy M, Dautin A, et al. Knockout of insulin-like growth factor-1 receptor impairs distal lung morphogenesis. PLoS ONE. 2012;7:e48071 pubmed 出版商

Weng C, Cai J, Wen J, Yuan H, Yang K, Imperato McGinley J, et al. Differential effects of estrogen receptor ligands on regulation of dihydrotestosterone-induced cell proliferation in endothelial and prostate cancer cells. Int J Oncol. 2013;42:327-37 pubmed 出版商

Xu Z, Yang Q, Ma L, Liu S, Chen G, Wu Y, et al. Deficits in LTP induction by 5-HT2A receptor antagonist in a mouse model for fragile X syndrome. PLoS ONE. 2012;7:e48741 pubmed 出版商

Wang S, Yang H, Xu G. Acupuncture Alleviates Colorectal Hypersensitivity and Correlates with the Regulatory Mechanism of TrpV1 and p-ERK. Evid Based Complement Alternat Med. 2012;2012:483123 pubmed 出版商

Cong W, Cai H, Wang R, Daimon C, Maudsley S, Raber K, et al. Altered hypothalamic protein expression in a rat model of Huntington's disease. PLoS ONE. 2012;7:e47240 pubmed 出版商

Earls L, Fricke R, Yu J, Berry R, Baldwin L, Zakharenko S. Age-dependent microRNA control of synaptic plasticity in 22q11 deletion syndrome and schizophrenia. J Neurosci. 2012;32:14132-44 pubmed 出版商

Paschon V, Higa G, Resende R, Britto L, Kihara A. Blocking of connexin-mediated communication promotes neuroprotection during acute degeneration induced by mechanical trauma. PLoS ONE. 2012;7:e45449 pubmed 出版商

Tripurani S, Cook R, Eldin K, Pangas S. BMP-specific SMADs function as novel repressors of PDGFA and modulate its expression in ovarian granulosa cells and tumors. Oncogene. 2013;32:3877-85 pubmed 出版商

Rodenas Ruano A, Chavez A, Cossio M, Castillo P, Zukin R. REST-dependent epigenetic remodeling promotes the developmental switch in synaptic NMDA receptors. Nat Neurosci. 2012;15:1382-90 pubmed 出版商

Ouchida M, Kanzaki H, Ito S, Hanafusa H, Jitsumori Y, Tamaru S, et al. Novel direct targets of miR-19a identified in breast cancer cells by a quantitative proteomic approach. PLoS ONE. 2012;7:e44095 pubmed 出版商

Singh S, Veo B, Kagalwala M, Shi W, Liang S, Majumder S. Dynamic status of REST in the mouse ESC pluripotency network. PLoS ONE. 2012;7:e43659 pubmed 出版商

Shimoda M, Sugiura T, Imajyo I, Ishii K, Chigita S, Seki K, et al. The T-box transcription factor Brachyury regulates epithelial-mesenchymal transition in association with cancer stem-like cells in adenoid cystic carcinoma cells. BMC Cancer. 2012;12:377 pubmed 出版商

Sountoulidis A, Stavropoulos A, Giaglis S, Apostolou E, Monteiro R, Chuva de Sousa Lopes S, et al. Activation of the canonical bone morphogenetic protein (BMP) pathway during lung morphogenesis and adult lung tissue repair. PLoS ONE. 2012;7:e41460 pubmed 出版商

Panneerdoss S, Chang Y, Buddavarapu K, Chen H, Shetty G, Wang H, et al. Androgen-responsive microRNAs in mouse Sertoli cells. PLoS ONE. 2012;7:e41146 pubmed 出版商

Yang X, Rutnam Z, Jiao C, Wei D, Xie Y, Du J, et al. An anti-let-7 sponge decoys and decays endogenous let-7 functions. Cell Cycle. 2012;11:3097-108 pubmed 出版商

Munk M, Memon A, Goetze J, Nielsen L, Nexo E, Sorensen B. Hypoxia changes the expression of the epidermal growth factor (EGF) system in human hearts and cultured cardiomyocytes. PLoS ONE. 2012;7:e40243 pubmed 出版商

Semaan S, Wang X, Marshall A, Sang Q. Identification of Potential Glycoprotein Biomarkers in Estrogen Receptor Positive (ER+) and Negative (ER-) Human Breast Cancer Tissues by LC-LTQ/FT-ICR Mass Spectrometry. J Cancer. 2012;3:269-84 pubmed 出版商

Kobayashi K, Jakt L, Nishikawa S. Epigenetic regulation of the neuroblastoma genes, Arid3b and Mycn. Oncogene. 2013;32:2640-8 pubmed 出版商

Dittmar M, Petermichl W, Schlachetzki F, Graf B, Gruber M. Isoflurane induces endothelial apoptosis of the post-hypoxic blood-brain barrier in a transdifferentiated human umbilical vein endothelial cell model. PLoS ONE. 2012;7:e38260 pubmed 出版商

Tchorz J, Tome M, Cloëtta D, Sivasankaran B, Grzmil M, Huber R, et al. Constitutive Notch2 signaling in neural stem cells promotes tumorigenic features and astroglial lineage entry. Cell Death Dis. 2012;3:e325 pubmed 出版商

Haschemi A, Kosma P, Gille L, Evans C, Burant C, Starkl P, et al. The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism. Cell Metab. 2012;15:813-26 pubmed 出版商

Jin H, Hong S, Woo S, Lee J, Choe T, Kim E, et al. Silencing of Twist1 sensitizes NSCLC cells to cisplatin via AMPK-activated mTOR inhibition. Cell Death Dis. 2012;3:e319 pubmed 出版商

Lorenzi T, Turi A, Lorenzi M, Paolinelli F, Mancioli F, La Sala L, et al. Placental expression of CD100, CD72 and CD45 is dysregulated in human miscarriage. PLoS ONE. 2012;7:e35232 pubmed 出版商

Hdud I, El Shafei A, Loughna P, Barrett Jolley R, Mobasheri A. Expression of Transient Receptor Potential Vanilloid (TRPV) channels in different passages of articular chondrocytes. Int J Mol Sci. 2012;13:4433-45 pubmed 出版商

Zhang Y, Cooke M, Panjwani S, Cao K, Krauth B, Ho P, et al. Histone h1 depletion impairs embryonic stem cell differentiation. PLoS Genet. 2012;8:e1002691 pubmed 出版商

Tung E, Wong B, Yau T, Ng I. Upregulation of the Wnt co-receptor LRP6 promotes hepatocarcinogenesis and enhances cell invasion. PLoS ONE. 2012;7:e36565 pubmed 出版商

Perugorria M, Wilson C, Zeybel M, Walsh M, Amin S, Robinson S, et al. Histone methyltransferase ASH1 orchestrates fibrogenic gene transcription during myofibroblast transdifferentiation. Hepatology. 2012;56:1129-39 pubmed 出版商

Selcuk M, Aygen B, Dogukan A, Tuzcu Z, Akdemir F, Komorowski J, et al. Chromium picolinate and chromium histidinate protects against renal dysfunction by modulation of NF-?B pathway in high-fat diet fed and Streptozotocin-induced diabetic rats. Nutr Metab (Lond). 2012;9:30 pubmed 出版商

Sato A, Ohtaki H, Tsumuraya T, Song D, Ohara K, Asano M, et al. Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury. J Neuroinflammation. 2012;9:65 pubmed 出版商

Shakibaei M, Allaway D, Nebrich S, Mobasheri A. Botanical Extracts from Rosehip (Rosa canina), Willow Bark (Salix alba), and Nettle Leaf (Urtica dioica) Suppress IL-1?-Induced NF-?B Activation in Canine Articular Chondrocytes. Evid Based Complement Alternat Med. 2012;2012:509383 pubmed 出版商

Tinahones F, Coín Aragüez L, Mayas M, Garcia Fuentes E, Hurtado del Pozo C, Vendrell J, et al. Obesity-associated insulin resistance is correlated to adipose tissue vascular endothelial growth factors and metalloproteinase levels. BMC Physiol. 2012;12:4 pubmed 出版商

Everitt A, Clare S, Pertel T, John S, Wash R, Smith S, et al. IFITM3 restricts the morbidity and mortality associated with influenza. Nature. 2012;484:519-23 pubmed 出版商

Wong V, Stange D, Page M, Buczacki S, Wabik A, Itami S, et al. Lrig1 controls intestinal stem-cell homeostasis by negative regulation of ErbB signalling. Nat Cell Biol. 2012;14:401-8 pubmed 出版商

Kategaya L, Hilliard A, Zhang L, Asara J, Ptacek L, Fu Y. Casein kinase 1 proteomics reveal prohibitin 2 function in molecular clock. PLoS ONE. 2012;7:e31987 pubmed 出版商

Rivera Gonzalez G, Droop A, Rippon H, Tiemann K, Pellacani D, Georgopoulos L, et al. Retinoic acid and androgen receptors combine to achieve tissue specific control of human prostatic transglutaminase expression: a novel regulatory network with broader significance. Nucleic Acids Res. 2012;40:4825-40 pubmed 出版商

Zhou M, Xu A, Tam P, Lam K, Huang B, Liang Y, et al. Upregulation of UCP2 by adiponectin: the involvement of mitochondrial superoxide and hnRNP K. PLoS ONE. 2012;7:e32349 pubmed 出版商

Fliss P, Jowers T, Brinkmann M, Holstermann B, Mack C, Dickinson P, et al. Viral mediated redirection of NEMO/IKK? to autophagosomes curtails the inflammatory cascade. PLoS Pathog. 2012;8:e1002517 pubmed 出版商

Zhang J, Seigneur E, Pandey M, Loshakov A, Dagur P, Connelly P, et al. The EIF4EBP3 translational repressor is a marker of CDC73 tumor suppressor haploinsufficiency in a parathyroid cancer syndrome. Cell Death Dis. 2012;3:266 pubmed 出版商

Orlando L, Sanchez Ripoll Y, Foster J, Bone H, Giachino C, Welham M. Differential coupling of self-renewal signaling pathways in murine induced pluripotent stem cells. PLoS ONE. 2012;7:e30234 pubmed 出版商

Sharma S, Gerke D, Han H, Jeong S, Stallcup M, Jones P, et al. Lysine methyltransferase G9a is not required for DNMT3A/3B anchoring to methylated nucleosomes and maintenance of DNA methylation in somatic cells. Epigenetics Chromatin. 2012;5:3 pubmed 出版商

Durfort T, Tkach M, Meschaninova M, Rivas M, Elizalde P, Venyaminova A, et al. Small interfering RNA targeted to IGF-IR delays tumor growth and induces proinflammatory cytokines in a mouse breast cancer model. PLoS ONE. 2012;7:e29213 pubmed 出版商

Velikkakath A, Nishimura T, Oita E, Ishihara N, Mizushima N. Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets. Mol Biol Cell. 2012;23:896-909 pubmed 出版商

Tanaka T, Kai S, Koyama T, Daijo H, Adachi T, Fukuda K, et al. General anesthetics inhibit erythropoietin induction under hypoxic conditions in the mouse brain. PLoS ONE. 2011;6:e29378 pubmed 出版商

Rashmi R, Eckes B, Glockner G, Groth M, Neumann S, Gloy J, et al. The nuclear envelope protein Nesprin-2 has roles in cell proliferation and differentiation during wound healing. Nucleus. 2012;3:172-86 pubmed 出版商

Feeley E, Sims J, John S, Chin C, Pertel T, Chen L, et al. IFITM3 inhibits influenza A virus infection by preventing cytosolic entry. PLoS Pathog. 2011;7:e1002337 pubmed 出版商

Leang R, Wu T, Hwang S, Liang L, Tong L, Truong J, et al. The anti-interferon activity of conserved viral dUTPase ORF54 is essential for an effective MHV-68 infection. PLoS Pathog. 2011;7:e1002292 pubmed 出版商

Karasneh G, Ali M, Shukla D. An important role for syndecan-1 in herpes simplex virus type-1 induced cell-to-cell fusion and virus spread. PLoS ONE. 2011;6:e25252 pubmed 出版商

Otsuka M, Takata A, Yoshikawa T, Kojima K, Kishikawa T, Shibata C, et al. Receptor for activated protein kinase C: requirement for efficient microRNA function and reduced expression in hepatocellular carcinoma. PLoS ONE. 2011;6:e24359 pubmed 出版商

Hagihara H, Ohira K, Toyama K, Miyakawa T. Expression of the AMPA Receptor Subunits GluR1 and GluR2 is Associated with Granule Cell Maturation in the Dentate Gyrus. Front Neurosci. 2011;5:100 pubmed 出版商

Steininger A, Möbs M, Ullmann R, Köchert K, Kreher S, Lamprecht B, et al. Genomic loss of the putative tumor suppressor gene E2A in human lymphoma. J Exp Med. 2011;208:1585-93 pubmed 出版商

Mandel I, Paperna T, Glass Marmor L, Volkowich A, Badarny S, Schwartz I, et al. Tight junction proteins expression and modulation in immune cells and multiple sclerosis. J Cell Mol Med. 2012;16:765-75 pubmed 出版商

Kertész Z, Gyori D, Körmendi S, Fekete T, Kis Toth K, Jakus Z, et al. Phospholipase C?2 is required for basal but not oestrogen deficiency-induced bone resorption. Eur J Clin Invest. 2012;42:49-60 pubmed 出版商

Giovinazzi S, Lindsay C, Morozov V, Escobar Cabrera E, Summers M, Han H, et al. Regulation of mitosis and taxane response by Daxx and Rassf1. Oncogene. 2012;31:13-26 pubmed 出版商

Joseph J, Seervi M, Sobhan P, Retnabai S. High throughput ratio imaging to profile caspase activity: potential application in multiparameter high content apoptosis analysis and drug screening. PLoS ONE. 2011;6:e20114 pubmed 出版商

E X, Pickering M, Debatis M, Castillo J, Lagadinos A, Wang S, et al. An E2F1-mediated DNA damage response contributes to the replication of human cytomegalovirus. PLoS Pathog. 2011;7:e1001342 pubmed 出版商

Wang D, Garcia Bassets I, Benner C, Li W, Su X, Zhou Y, et al. Reprogramming transcription by distinct classes of enhancers functionally defined by eRNA. Nature. 2011;474:390-4 pubmed 出版商

Jin Q, Chen H, Luo A, Ding F, Liu Z. S100A14 stimulates cell proliferation and induces cell apoptosis at different concentrations via receptor for advanced glycation end products (RAGE). PLoS ONE. 2011;6:e19375 pubmed 出版商

Andersen P, Xu F, Ziola B, McGregor W, Xiao W. Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sites. Mol Biol Cell. 2011;22:2373-83 pubmed 出版商

Tuzcu M, Sahin N, Orhan C, Agca C, Akdemir F, Tuzcu Z, et al. Impact of chromium histidinate on high fat diet induced obesity in rats. Nutr Metab (Lond). 2011;8:28 pubmed 出版商

Rizvi F, Heimann T, Herrnreiter A, O Brien W. Mitochondrial dysfunction links ceramide activated HRK expression and cell death. PLoS ONE. 2011;6:e18137 pubmed 出版商

Yin J, Yan X, Yao X, Zhang Y, Shan Y, Mao N, et al. Secretion of annexin A3 from ovarian cancer cells and its association with platinum resistance in ovarian cancer patients. J Cell Mol Med. 2012;16:337-48 pubmed 出版商

Fujimura A, Michiue H, Nishiki T, Ohmori I, Wei F, Matsui H, et al. Expression of a constitutively active calcineurin encoded by an intron-retaining mRNA in follicular keratinocytes. PLoS ONE. 2011;6:e17685 pubmed 出版商

Blaser C, Wittwer M, Grandgirard D, Leib S. Adjunctive dexamethasone affects the expression of genes related to inflammation, neurogenesis and apoptosis in infant rat pneumococcal meningitis. PLoS ONE. 2011;6:e17840 pubmed 出版商

Rakovic A, Grünewald A, Kottwitz J, Brüggemann N, Pramstaller P, Lohmann K, et al. Mutations in PINK1 and Parkin impair ubiquitination of Mitofusins in human fibroblasts. PLoS ONE. 2011;6:e16746 pubmed 出版商

Huang Y, Chen L, Zhou Y, Liu H, Yang J, Liu Z, et al. UXT-V1 protects cells against TNF-induced apoptosis through modulating complex II formation. Mol Biol Cell. 2011;22:1389-97 pubmed 出版商

Pontarin G, Ferraro P, Rampazzo C, Kollberg G, Holme E, Reichard P, et al. Deoxyribonucleotide metabolism in cycling and resting human fibroblasts with a missense mutation in p53R2, a subunit of ribonucleotide reductase. J Biol Chem. 2011;286:11132-40 pubmed 出版商

Stieler J, Bullmann T, Kohl F, Tøien Ø, Brückner M, Hartig W, et al. The physiological link between metabolic rate depression and tau phosphorylation in mammalian hibernation. PLoS ONE. 2011;6:e14530 pubmed 出版商

Lee D, Jeyapalan Z, Fang L, Yang J, Zhang Y, Yee A, et al. Expression of versican 3'-untranslated region modulates endogenous microRNA functions. PLoS ONE. 2010;5:e13599 pubmed 出版商

Andres A, Dennis M, Kretzschmar W, Cannons J, Lee Lin S, Hurle B, et al. Balancing selection maintains a form of ERAP2 that undergoes nonsense-mediated decay and affects antigen presentation. PLoS Genet. 2010;6:e1001157 pubmed 出版商

Dohi K, Ohtaki H, Nakamachi T, Yofu S, Satoh K, Miyamoto K, et al. Gp91phox (NOX2) in classically activated microglia exacerbates traumatic brain injury. J Neuroinflammation. 2010;7:41 pubmed 出版商

Lindenmeyer M, Eichinger F, Sen K, Anders H, Edenhofer I, Mattinzoli D, et al. Systematic analysis of a novel human renal glomerulus-enriched gene expression dataset. PLoS ONE. 2010;5:e11545 pubmed 出版商

Kashiwagi Y, Kato N, Sassa T, Nishitsuka K, Yamamoto T, Takamura H, et al. Cotylenin A inhibits cell proliferation and induces apoptosis and PAX6 mRNA transcripts in retinoblastoma cell lines. Mol Vis. 2010;16:970-82 pubmed

Brunmeir R, Lagger S, Simboeck E, Sawicka A, Egger G, Hagelkruys A, et al. Epigenetic regulation of a murine retrotransposon by a dual histone modification mark. PLoS Genet. 2010;6:e1000927 pubmed 出版商

Han S, Yun H, Son D, Tompkins V, Peng L, Chung S, et al. NF-kappaB/STAT3/PI3K signaling crosstalk in iMyc E mu B lymphoma. Mol Cancer. 2010;9:97 pubmed 出版商

Ehlert E, Eggers R, Niclou S, Verhaagen J. Cellular toxicity following application of adeno-associated viral vector-mediated RNA interference in the nervous system. BMC Neurosci. 2010;11:20 pubmed 出版商

Berger P, Tersar K, Ballmer Hofer K, Suter U. The CMT4B disease-causing proteins MTMR2 and MTMR13/SBF2 regulate AKT signalling. J Cell Mol Med. 2011;15:307-15 pubmed 出版商

Werz C, Kohler K, Hafen E, Stocker H. The Drosophila SH2B family adaptor Lnk acts in parallel to chico in the insulin signaling pathway. PLoS Genet. 2009;5:e1000596 pubmed 出版商

Mousavi S, Fønhus M, Berg T. Up-regulation of uPARAP/Endo180 during culture activation of rat hepatic stellate cells and its presence in hepatic stellate cell lines from different species. BMC Cell Biol. 2009;10:39 pubmed 出版商

Luce A, Courtin A, Levalois C, Altmeyer Morel S, Romeo P, Chevillard S, et al. Death receptor pathways mediate targeted and non-targeted effects of ionizing radiations in breast cancer cells. Carcinogenesis. 2009;30:432-9 pubmed 出版商

Stairs D, Nakagawa H, Klein Szanto A, Mitchell S, Silberg D, Tobias J, et al. Cdx1 and c-Myc foster the initiation of transdifferentiation of the normal esophageal squamous epithelium toward Barrett's esophagus. PLoS ONE. 2008;3:e3534 pubmed 出版商

Zoeller J, Iozzo R. Proteomic profiling of endorepellin angiostatic activity on human endothelial cells. Proteome Sci. 2008;6:7 pubmed 出版商

Datta A, Silverman L, Phipps A, Hiraragi H, Ratner L, Lairmore M. Human T-lymphotropic virus type-1 p30 alters cell cycle G2 regulation of T lymphocytes to enhance cell survival. Retrovirology. 2007;4:49 pubmed

Said H, Hagemann C, Stojic J, Schoemig B, Vince G, Flentje M, et al. GAPDH is not regulated in human glioblastoma under hypoxic conditions. BMC Mol Biol. 2007;8:55 pubmed

Cadinanos J, Bradley A. Generation of an inducible and optimized piggyBac transposon system. Nucleic Acids Res. 2007;35:e87 pubmed

Matthews J, Watson S, Tevendale M, Watson C, Clarke A. Caspase-dependent proteolytic cleavage of STAT3alpha in ES cells, in mammary glands undergoing forced involution and in breast cancer cell lines. BMC Cancer. 2007;7:29 pubmed

Takizawa N, Smith T, Nebl T, Crowley J, Palmieri S, Lifshitz L, et al. Supervillin modulation of focal adhesions involving TRIP6/ZRP-1. J Cell Biol. 2006;174:447-58 pubmed

Boyer L, Doye A, Rolando M, Flatau G, Munro P, Gounon P, et al. Induction of transient macroapertures in endothelial cells through RhoA inhibition by Staphylococcus aureus factors. J Cell Biol. 2006;173:809-19 pubmed

Muenzner P, Rohde M, Kneitz S, Hauck C. CEACAM engagement by human pathogens enhances cell adhesion and counteracts bacteria-induced detachment of epithelial cells. J Cell Biol. 2005;170:825-36 pubmed

Maehara K, Yamakoshi K, Ohtani N, Kubo Y, Takahashi A, Arase S, et al. Reduction of total E2F/DP activity induces senescence-like cell cycle arrest in cancer cells lacking functional pRB and p53. J Cell Biol. 2005;168:553-60 pubmed

Mishra R, Simonson M. Saturated free fatty acids and apoptosis in microvascular mesangial cells: palmitate activates pro-apoptotic signaling involving caspase 9 and mitochondrial release of endonuclease G. Cardiovasc Diabetol. 2005;4:2 pubmed

Holaska J, Kowalski A, Wilson K. Emerin caps the pointed end of actin filaments: evidence for an actin cortical network at the nuclear inner membrane. PLoS Biol. 2004;2:E231 pubmed 出版商

Djuzenova C, Muhl B, Schakowski R, Oppitz U, Flentje M. Normal expression of DNA repair proteins, hMre11, Rad50 and Rad51 but protracted formation of Rad50 containing foci in X-irradiated skin fibroblasts from radiosensitive cancer patients. Br J Cancer. 2004;90:2356-63 pubmed

Hsia D, Mitra S, Hauck C, Streblow D, Nelson J, Ilic D, et al. Differential regulation of cell motility and invasion by FAK. J Cell Biol. 2003;160:753-67 pubmed