Bianchi Smiraglia A, Bagati A, Fink E, Affronti H, Lipchick B, Moparthy S, et al. Inhibition of the aryl hydrocarbon receptor/polyamine biosynthesis axis suppresses multiple myeloma. J Clin Invest. 2018;128:4682-4696 pubmed 出版商

Kane M, Rebensburg S, Takata M, Zang T, Yamashita M, Kvaratskhelia M, et al. Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2. elife. 2018;7: pubmed 出版商

Cagnetta R, Frese C, Shigeoka T, Krijgsveld J, Holt C. Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome. Neuron. 2018;99:29-46.e4 pubmed 出版商

Trepte P, Kruse S, Kostova S, Hoffmann S, Buntru A, Tempelmeier A, et al. LuTHy: a double-readout bioluminescence-based two-hybrid technology for quantitative mapping of protein-protein interactions in mammalian cells. Mol Syst Biol. 2018;14:e8071 pubmed 出版商

Reipert S, Goldammer H, Richardson C, Goldberg M, Hawkins T, Hollergschwandtner E, et al. Agitation Modules: Flexible Means to Accelerate Automated Freeze Substitution. J Histochem Cytochem. 2018;66:903-921 pubmed 出版商

Bernal A, Moltó Abad M, Dominguez D, Tusell L. Acute telomere deprotection prevents ongoing BFB cycles and rampant instability in p16INK4a-deficient epithelial cells. Oncotarget. 2018;9:27151-27170 pubmed 出版商

Rapino F, Delaunay S, Rambow F, Zhou Z, Tharun L, de Tullio P, et al. Codon-specific translation reprogramming promotes resistance to targeted therapy. Nature. 2018;558:605-609 pubmed 出版商

Gozdecka M, Meduri E, Mazan M, Tzelepis K, Dudek M, Knights A, et al. UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs. Nat Genet. 2018;50:883-894 pubmed 出版商

Bartusch C, Döring T, Prange R. Rab33B Controls Hepatitis B Virus Assembly by Regulating Core Membrane Association and Nucleocapsid Processing. Viruses. 2017;9: pubmed 出版商

Dong C, Xu H, Zhang R, Tanaka N, Takeichi M, Meng W. CAMSAP3 accumulates in the pericentrosomal area and accompanies microtubule release from the centrosome via katanin. J Cell Sci. 2017;130:1709-1715 pubmed 出版商

Grzelak C, Sigglekow N, Tirnitz Parker J, Hamson E, Warren A, Maneck B, et al. Widespread GLI expression but limited canonical hedgehog signaling restricted to the ductular reaction in human chronic liver disease. PLoS ONE. 2017;12:e0171480 pubmed 出版商

Tormos A, Rius Pérez S, Jorques M, Rada P, Ramírez L, Valverde A, et al. p38α regulates actin cytoskeleton and cytokinesis in hepatocytes during development and aging. PLoS ONE. 2017;12:e0171738 pubmed 出版商

Lin J, Kumari S, Kim C, Van T, Wachsmuth L, Polykratis A, et al. RIPK1 counteracts ZBP1-mediated necroptosis to inhibit inflammation. Nature. 2016;540:124-128 pubmed 出版商

Vasconcelos F, Sessa A, Laranjeira C, Raposo A, Teixeira V, Hagey D, et al. MyT1 Counteracts the Neural Progenitor Program to Promote Vertebrate Neurogenesis. Cell Rep. 2016;17:469-483 pubmed 出版商

Qi L, Jafari N, Li X, Chen Z, Li L, Hytönen V, et al. Talin2-mediated traction force drives matrix degradation and cell invasion. J Cell Sci. 2016;129:3661-3674 pubmed

Wolfe S, Workman E, Heaney C, Niere F, Namjoshi S, Cacheaux L, et al. FMRP regulates an ethanol-dependent shift in GABABR function and expression with rapid antidepressant properties. Nat Commun. 2016;7:12867 pubmed 出版商

Hu H, Umemori H, Hsueh Y. Postsynaptic SDC2 induces transsynaptic signaling via FGF22 for bidirectional synaptic formation. Sci Rep. 2016;6:33592 pubmed 出版商

Carbonneau M, M Gagné L, Lalonde M, Germain M, Motorina A, Guiot M, et al. The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway. Nat Commun. 2016;7:12700 pubmed 出版商

Fernández Majada V, Welz P, Ermolaeva M, Schell M, Adam A, Dietlein F, et al. The tumour suppressor CYLD regulates the p53 DNA damage response. Nat Commun. 2016;7:12508 pubmed 出版商

Li L, Han L, Zhang J, Liu X, Ma R, Hou X, et al. Epsin2 promotes polarity establishment and meiotic division through activating Cdc42 in mouse oocyte. Oncotarget. 2016;7:50927-50936 pubmed 出版商

Li L, Shi L, Yang S, Yan R, Zhang D, Yang J, et al. SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability. Nat Commun. 2016;7:12235 pubmed 出版商

Lu R, Hu X, Zhou J, Sun J, Zhu A, Xu X, et al. COPS5 amplification and overexpression confers tamoxifen-resistance in ER?-positive breast cancer by degradation of NCoR. Nat Commun. 2016;7:12044 pubmed 出版商

Skoge R, Ziegler M. SIRT2 inactivation reveals a subset of hyperacetylated perinuclear microtubules inaccessible to HDAC6. J Cell Sci. 2016;129:2972-82 pubmed 出版商

Konopacki F, Wong H, Dwivedy A, Bellon A, Blower M, Holt C. ESCRT-II controls retinal axon growth by regulating DCC receptor levels and local protein synthesis. Open Biol. 2016;6:150218 pubmed 出版商

Nutter C, Jaworski E, Verma S, Deshmukh V, Wang Q, Botvinnik O, et al. Dysregulation of RBFOX2 Is an Early Event in Cardiac Pathogenesis of Diabetes. Cell Rep. 2016;15:2200-2213 pubmed 出版商

Ma N, Ma Y, Nakashima A, Kikkawa U, Furuyashiki T. The Loss of Lam2 and Npr2-Npr3 Diminishes the Vacuolar Localization of Gtr1-Gtr2 and Disinhibits TORC1 Activity in Fission Yeast. PLoS ONE. 2016;11:e0156239 pubmed 出版商

Lopez A, Kugelman J, Garcia Rivera J, Urias E, Salinas S, Fernandez Zapico M, et al. The Structure-Specific Recognition Protein 1 Associates with Lens Epithelium-Derived Growth Factor Proteins and Modulates HIV-1 Replication. J Mol Biol. 2016;428:2814-31 pubmed 出版商

Ramesh S, Singh A, Cibi D, Hausenloy D, Singh M. In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart. J Vis Exp. 2016;: pubmed 出版商

Pourcet B, Gage M, León T, Waddington K, Pello O, Steffensen K, et al. The nuclear receptor LXR modulates interleukin-18 levels in macrophages through multiple mechanisms. Sci Rep. 2016;6:25481 pubmed 出版商

Humoud M, Doyle N, Royall E, Willcocks M, Sorgeloos F, van Kuppeveld F, et al. Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage. J Virol. 2016;90:6489-6501 pubmed 出版商

Krall A, Xu S, Graeber T, Braas D, Christofk H. Asparagine promotes cancer cell proliferation through use as an amino acid exchange factor. Nat Commun. 2016;7:11457 pubmed 出版商

Kim S, Choi K, Cho S, Yun S, Jeon J, Koh Y, et al. Fisetin stimulates autophagic degradation of phosphorylated tau via the activation of TFEB and Nrf2 transcription factors. Sci Rep. 2016;6:24933 pubmed 出版商

Rodriguez Ortiz C, Flores J, Valenzuela J, Rodriguez G, Zumkehr J, Tran D, et al. The Myoblast C2C12 Transfected with Mutant Valosin-Containing Protein Exhibits Delayed Stress Granule Resolution on Oxidative Stress. Am J Pathol. 2016;186:1623-34 pubmed 出版商

Kwenda L, Collins C, Dattoli A, Dunleavy E. Nucleolar activity and CENP-C regulate CENP-A and CAL1 availability for centromere assembly in meiosis. Development. 2016;143:1400-12 pubmed 出版商

Papke B, Murarka S, Vogel H, Martín Gago P, Kovacevic M, Truxius D, et al. Identification of pyrazolopyridazinones as PDE? inhibitors. Nat Commun. 2016;7:11360 pubmed 出版商

Saito A, Ferhadian D, Sowd G, Serrao E, Shi J, Halambage U, et al. Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74. J Virol. 2016;90:5808-5823 pubmed 出版商

Chu C, Ossipova O, Ioannou A, Sokol S. Prickle3 synergizes with Wtip to regulate basal body organization and cilia growth. Sci Rep. 2016;6:24104 pubmed 出版商

Li Y, Liu D, López Paz C, OLSON B, Umen J. A new class of cyclin dependent kinase in Chlamydomonas is required for coupling cell size to cell division. elife. 2016;5:e10767 pubmed 出版商

Vlantis K, Wullaert A, Polykratis A, Kondylis V, Dannappel M, Schwarzer R, et al. NEMO Prevents RIP Kinase 1-Mediated Epithelial Cell Death and Chronic Intestinal Inflammation by NF-κB-Dependent and -Independent Functions. Immunity. 2016;44:553-567 pubmed 出版商

Atiq R, Hertz R, Eldad S, Smeir E, Bar Tana J. Suppression of B-Raf(V600E) cancers by MAPK hyper-activation. Oncotarget. 2016;7:18694-704 pubmed 出版商

Swenson S, Cannon A, Harris N, Taylor N, Fox J, Khalimonchuk O. Analysis of Oligomerization Properties of Heme a Synthase Provides Insights into Its Function in Eukaryotes. J Biol Chem. 2016;291:10411-25 pubmed 出版商

Moiseeva O, Lopes Paciencia S, Huot G, Lessard F, Ferbeyre G. Permanent farnesylation of lamin A mutants linked to progeria impairs its phosphorylation at serine 22 during interphase. Aging (Albany NY). 2016;8:366-81 pubmed

Ost M, Coleman V, Voigt A, van Schothorst E, Keipert S, van der Stelt I, et al. Muscle mitochondrial stress adaptation operates independently of endogenous FGF21 action. Mol Metab. 2016;5:79-90 pubmed 出版商

Ren C, Yang Y, Sun J, Wu Z, Zhang R, Shen D, et al. Exercise Training Improves the Altered Renin-Angiotensin System in the Rostral Ventrolateral Medulla of Hypertensive Rats. Oxid Med Cell Longev. 2016;2016:7413963 pubmed 出版商

Kim N, Kim M, Sung P, Bae Y, Shin E, Yoo J. Interferon-inducible protein SCOTIN interferes with HCV replication through the autolysosomal degradation of NS5A. Nat Commun. 2016;7:10631 pubmed 出版商

Chen S, Blank M, Iyer A, Huang B, Wang L, Grummt I, et al. SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing. Nat Commun. 2016;7:10734 pubmed 出版商

Yau K, Schätzle P, Tortosa E, Pagès S, Holtmaat A, Kapitein L, et al. Dendrites In Vitro and In Vivo Contain Microtubules of Opposite Polarity and Axon Formation Correlates with Uniform Plus-End-Out Microtubule Orientation. J Neurosci. 2016;36:1071-85 pubmed 出版商

Wood L, Booth D, Vargiu G, Ohta S, deLima Alves F, Samejima K, et al. Auxin/AID versus conventional knockouts: distinguishing the roles of CENP-T/W in mitotic kinetochore assembly and stability. Open Biol. 2016;6:150230 pubmed 出版商

Villarroel Espíndola F, Tapia C, González Stegmaier R, Concha I, Slebe J. Polyglucosan Molecules Induce Mitochondrial Impairment and Apoptosis in Germ Cells Without Affecting the Integrity and Functionality of Sertoli Cells. J Cell Physiol. 2016;231:2142-52 pubmed 出版商

Watari K, Shibata T, Nabeshima H, Shinoda A, Fukunaga Y, Kawahara A, et al. Impaired differentiation of macrophage lineage cells attenuates bone remodeling and inflammatory angiogenesis in Ndrg1 deficient mice. Sci Rep. 2016;6:19470 pubmed 出版商

Avgustinova A, Iravani M, Robertson D, Fearns A, Gao Q, Klingbeil P, et al. Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness. Nat Commun. 2016;7:10305 pubmed 出版商

Quétier I, Marshall J, Spencer Dene B, Lachmann S, Casamassima A, Franco C, et al. Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion. Cell Rep. 2016;14:440-448 pubmed 出版商

Ketel K, Krauss M, Nicot A, Puchkov D, Wieffer M, Müller R, et al. A phosphoinositide conversion mechanism for exit from endosomes. Nature. 2016;529:408-12 pubmed 出版商

Puvirajesinghe T, Bertucci F, Jain A, Scerbo P, Belotti E, Audebert S, et al. Identification of p62/SQSTM1 as a component of non-canonical Wnt VANGL2-JNK signalling in breast cancer. Nat Commun. 2016;7:10318 pubmed 出版商

Sansó M, Levin R, Lipp J, Wang V, Greifenberg A, Quezada E, et al. P-TEFb regulation of transcription termination factor Xrn2 revealed by a chemical genetic screen for Cdk9 substrates. Genes Dev. 2016;30:117-31 pubmed 出版商

Ghosh A, Ghosh S, Dasgupta D, Ghosh A, Datta S, Sikdar N, et al. Hepatitis B Virus X Protein Upregulates hELG1/ ATAD5 Expression through E2F1 in Hepatocellular Carcinoma. Int J Biol Sci. 2016;12:30-41 pubmed 出版商

Edmonds M, Boyd K, Moyo T, Mitra R, Duszynski R, Arrate M, et al. MicroRNA-31 initiates lung tumorigenesis and promotes mutant KRAS-driven lung cancer. J Clin Invest. 2016;126:349-64 pubmed 出版商

Ksionda O, Melton A, Bache J, Tenhagen M, Bakker J, Harvey R, et al. RasGRP1 overexpression in T-ALL increases basal nucleotide exchange on Ras rendering the Ras/PI3K/Akt pathway responsive to protumorigenic cytokines. Oncogene. 2016;35:3658-68 pubmed 出版商

Teng R, Wu T, Afolayan A, Konduri G. Nitrotyrosine impairs mitochondrial function in fetal lamb pulmonary artery endothelial cells. Am J Physiol Cell Physiol. 2016;310:C80-8 pubmed 出版商

Chesser A, Ganeshan V, Yang J, Johnson G. Epigallocatechin-3-gallate enhances clearance of phosphorylated tau in primary neurons. Nutr Neurosci. 2016;19:21-31 pubmed 出版商

Drusenheimer N, Migdal B, Jäckel S, Tveriakhina L, Scheider K, Schulz K, et al. The Mammalian Orthologs of Drosophila Lgd, CC2D1A and CC2D1B, Function in the Endocytic Pathway, but Their Individual Loss of Function Does Not Affect Notch Signalling. PLoS Genet. 2015;11:e1005749 pubmed 出版商

Dias J, Rito T, Torlai Triglia E, Kukalev A, Ferrai C, Chotalia M, et al. Methylation of RNA polymerase II non-consensus Lysine residues marks early transcription in mammalian cells. elife. 2015;4: pubmed 出版商

Lee E, Jin D, Lee B, Kim Y, Han J, Shim Y, et al. Negative effect of cyclin D1 overexpression on recurrence-free survival in stage II-IIIA lung adenocarcinoma and its expression modulation by vorinostat in vitro. BMC Cancer. 2015;15:982 pubmed 出版商

Pillai S, Nguyen J, Johnson J, Haura E, Coppola D, Chellappan S. Tank binding kinase 1 is a centrosome-associated kinase necessary for microtubule dynamics and mitosis. Nat Commun. 2015;6:10072 pubmed 出版商

Leclercq A, Veillat V, Loriot S, Spuul P, Madonna F, Roques X, et al. A Methodology for Concomitant Isolation of Intimal and Adventitial Endothelial Cells from the Human Thoracic Aorta. PLoS ONE. 2015;10:e0143144 pubmed 出版商

Tonsing Carter E, Bailey B, Saadatzadeh M, Ding J, Wang H, Sinn A, et al. Potentiation of Carboplatin-Mediated DNA Damage by the Mdm2 Modulator Nutlin-3a in a Humanized Orthotopic Breast-to-Lung Metastatic Model. Mol Cancer Ther. 2015;14:2850-63 pubmed 出版商

Han L, Ge J, Zhang L, Ma R, Hou X, Li B, et al. Sirt6 depletion causes spindle defects and chromosome misalignment during meiosis of mouse oocyte. Sci Rep. 2015;5:15366 pubmed 出版商

Bolukbasi M, Gupta A, Oikemus S, Derr A, Garber M, Brodsky M, et al. DNA-binding-domain fusions enhance the targeting range and precision of Cas9. Nat Methods. 2015;12:1150-6 pubmed 出版商

Vajravelu B, Hong K, Al Maqtari T, Cao P, Keith M, Wysoczynski M, et al. C-Kit Promotes Growth and Migration of Human Cardiac Progenitor Cells via the PI3K-AKT and MEK-ERK Pathways. PLoS ONE. 2015;10:e0140798 pubmed 出版商

Renga B, Francisci D, Carino A, Marchianò S, Cipriani S, Chiara Monti M, et al. The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma. Sci Rep. 2015;5:15403 pubmed 出版商

Klar A, Gopinadh J, Kleber S, Wadle A, Renner C. Treatment with 5-Aza-2'-Deoxycytidine Induces Expression of NY-ESO-1 and Facilitates Cytotoxic T Lymphocyte-Mediated Tumor Cell Killing. PLoS ONE. 2015;10:e0139221 pubmed 出版商

Aviner R, Shenoy A, Elroy Stein O, Geiger T. Uncovering Hidden Layers of Cell Cycle Regulation through Integrative Multi-omic Analysis. PLoS Genet. 2015;11:e1005554 pubmed 出版商

D Amato N, Rogers T, Gordon M, Greene L, Cochrane D, Spoelstra N, et al. A TDO2-AhR signaling axis facilitates anoikis resistance and metastasis in triple-negative breast cancer. Cancer Res. 2015;75:4651-64 pubmed 出版商

Dong H, Chen Z, Wang C, Xiong Z, Zhao W, Jia C, et al. Rictor Regulates Spermatogenesis by Controlling Sertoli Cell Cytoskeletal Organization and Cell Polarity in the Mouse Testis. Endocrinology. 2015;156:4244-56 pubmed 出版商

Kruzliak P, Hare D, Zvonícek V, Klimas J, Zulli A. Simvastatin impairs the induction of pulmonary fibrosis caused by a western style diet: a preliminary study. J Cell Mol Med. 2015;19:2647-54 pubmed 出版商

Barbone D, Follo C, Echeverry N, Gerbaudo V, Klabatsa A, Bueno R, et al. Autophagy Correlates with the Therapeutic Responsiveness of Malignant Pleural Mesothelioma in 3D Models. PLoS ONE. 2015;10:e0134825 pubmed 出版商

Kanfer G, Courtheoux T, Peterka M, Meier S, Soste M, Melnik A, et al. Mitotic redistribution of the mitochondrial network by Miro and Cenp-F. Nat Commun. 2015;6:8015 pubmed 出版商

Sutani T, Sakata T, Nakato R, Masuda K, Ishibashi M, Yamashita D, et al. Condensin targets and reduces unwound DNA structures associated with transcription in mitotic chromosome condensation. Nat Commun. 2015;6:7815 pubmed 出版商

Stiess M, Wegehingel S, Nguyen C, Nickel W, Bradke F, Cambridge S. A Dual SILAC Proteomic Labeling Strategy for Quantifying Constitutive and Cell-Cell Induced Protein Secretion. J Proteome Res. 2015;14:3229-38 pubmed 出版商

Navarro F, Lieberman J. miR-34 and p53: New Insights into a Complex Functional Relationship. PLoS ONE. 2015;10:e0132767 pubmed 出版商

Chen S, Okada M, Nakato R, Izumi K, Bando M, Shirahige K. The Deubiquitinating Enzyme USP7 Regulates Androgen Receptor Activity by Modulating Its Binding to Chromatin. J Biol Chem. 2015;290:21713-23 pubmed 出版商

Newell Litwa K, Badoual M, Asmussen H, Patel H, Whitmore L, Horwitz A. ROCK1 and 2 differentially regulate actomyosin organization to drive cell and synaptic polarity. J Cell Biol. 2015;210:225-42 pubmed 出版商

Li W, Hu Y, Oh S, Ma Q, Merkurjev D, Song X, et al. Condensin I and II Complexes License Full Estrogen Receptor α-Dependent Enhancer Activation. Mol Cell. 2015;59:188-202 pubmed 出版商

Beckman D, Santos L, Americo T, Ledo J, de Mello F, Linden R. Prion Protein Modulates Monoaminergic Systems and Depressive-like Behavior in Mice. J Biol Chem. 2015;290:20488-98 pubmed 出版商

Heinemann A, Cullinane C, De Paoli Iseppi R, Wilmott J, Gunatilake D, Madore J, et al. Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling. Oncotarget. 2015;6:21507-21 pubmed

Nishida H, Ikegami A, Kaneko C, Kakuma H, Nishi H, Tanaka N, et al. Dexamethasone and BCAA Failed to Modulate Muscle Mass and mTOR Signaling in GH-Deficient Rats. PLoS ONE. 2015;10:e0128805 pubmed 出版商

McGirt L, Jia P, Baerenwald D, Duszynski R, Dahlman K, Zic J, et al. Whole-genome sequencing reveals oncogenic mutations in mycosis fungoides. Blood. 2015;126:508-19 pubmed 出版商

Gierut J, Lyons J, Shah M, Genetti C, Breault D, Haigis K. Oncogenic K-Ras promotes proliferation in quiescent intestinal stem cells. Stem Cell Res. 2015;15:165-71 pubmed 出版商

Xie L, Pi X, Townley Tilson W, Li N, Wehrens X, Entman M, et al. PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban. J Clin Invest. 2015;125:2759-71 pubmed 出版商

Jinks R, Puffenberger E, Baple E, Harding B, Crino P, Fogo A, et al. Recessive nephrocerebellar syndrome on the Galloway-Mowat syndrome spectrum is caused by homozygous protein-truncating mutations of WDR73. Brain. 2015;138:2173-90 pubmed 出版商

Tembe V, Martino Echarri E, Marzec K, Mok M, Brodie K, Mills K, et al. The BARD1 BRCT domain contributes to p53 binding, cytoplasmic and mitochondrial localization, and apoptotic function. Cell Signal. 2015;27:1763-71 pubmed 出版商

Ketema M, Secades P, Kreft M, Nahidiazar L, Janssen H, Jalink K, et al. The rod domain is not essential for the function of plectin in maintaining tissue integrity. Mol Biol Cell. 2015;26:2402-17 pubmed 出版商

Naipal K, Raams A, Bruens S, Brandsma I, Verkaik N, Jaspers N, et al. Attenuated XPC expression is not associated with impaired DNA repair in bladder cancer. PLoS ONE. 2015;10:e0126029 pubmed 出版商

Isogai T, van der Kammen R, Innocenti M. SMIFH2 has effects on Formins and p53 that perturb the cell cytoskeleton. Sci Rep. 2015;5:9802 pubmed 出版商

Antonenkov V, Isomursu A, Mennerich D, Vapola M, Weiher H, Kietzmann T, et al. The Human Mitochondrial DNA Depletion Syndrome Gene MPV17 Encodes a Non-selective Channel That Modulates Membrane Potential. J Biol Chem. 2015;290:13840-61 pubmed 出版商

Ohashi M, Holthaus A, Calderwood M, Lai C, Krastins B, Sarracino D, et al. The EBNA3 family of Epstein-Barr virus nuclear proteins associates with the USP46/USP12 deubiquitination complexes to regulate lymphoblastoid cell line growth. PLoS Pathog. 2015;11:e1004822 pubmed 出版商

Akizu N, Cantagrel V, Zaki M, Al Gazali L, Wang X, Rosti R, et al. Biallelic mutations in SNX14 cause a syndromic form of cerebellar atrophy and lysosome-autophagosome dysfunction. Nat Genet. 2015;47:528-34 pubmed 出版商

Westcott J, Prechtl A, Maine E, Dang T, Esparza M, Sun H, et al. An epigenetically distinct breast cancer cell subpopulation promotes collective invasion. J Clin Invest. 2015;125:1927-43 pubmed 出版商

Ting P, Damoiseaux R, Titz B, Bradley K, Graeber T, Fernandez Vega V, et al. Identification of small molecules that disrupt signaling between ABL and its positive regulator RIN1. PLoS ONE. 2015;10:e0121833 pubmed 出版商

Xu G, Chapman J, Brandsma I, Yuan J, Mistrik M, Bouwman P, et al. REV7 counteracts DNA double-strand break resection and affects PARP inhibition. Nature. 2015;521:541-544 pubmed 出版商

Liu Y, Lee J, Ackerman S. Mutations in the microtubule-associated protein 1A (Map1a) gene cause Purkinje cell degeneration. J Neurosci. 2015;35:4587-98 pubmed 出版商

Burgess H, Mohr I. Cellular 5'-3' mRNA exonuclease Xrn1 controls double-stranded RNA accumulation and anti-viral responses. Cell Host Microbe. 2015;17:332-344 pubmed 出版商

Martínez Torres A, Quiney C, Attout T, Boullet H, Herbi L, Vela L, et al. CD47 agonist peptides induce programmed cell death in refractory chronic lymphocytic leukemia B cells via PLCγ1 activation: evidence from mice and humans. PLoS Med. 2015;12:e1001796 pubmed 出版商

Ducommun S, Deak M, Sumpton D, Ford R, Núñez Galindo A, Kussmann M, et al. Motif affinity and mass spectrometry proteomic approach for the discovery of cellular AMPK targets: identification of mitochondrial fission factor as a new AMPK substrate. Cell Signal. 2015;27:978-88 pubmed 出版商

Ohta S, Wood L, Toramoto I, Yagyu K, Fukagawa T, Earnshaw W. CENP-32 is required to maintain centrosomal dominance in bipolar spindle assembly. Mol Biol Cell. 2015;26:1225-37 pubmed 出版商

Sleiman N, McFarland T, Jones L, Cala S. Transitions of protein traffic from cardiac ER to junctional SR. J Mol Cell Cardiol. 2015;81:34-45 pubmed 出版商

Cuello Carrión F, Shortrede J, Alvarez Olmedo D, Cayado Gutiérrez N, Castro G, Zoppino F, et al. HER2 and β-catenin protein location: importance in the prognosis of breast cancer patients and their correlation when breast cancer cells suffer stressful situations. Clin Exp Metastasis. 2015;32:151-68 pubmed 出版商

Cheng Y, Chen P, Chiang H, Suen C, Hwang M, Lin T, et al. Candidate tumor suppressor B-cell translocation gene 3 impedes neoplastic progression by suppression of AKT. Cell Death Dis. 2015;6:e1584 pubmed 出版商

Jilg C, Ketscher A, Metzger E, Hummel B, Willmann D, Rüsseler V, et al. PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells. Oncotarget. 2014;5:12646-64 pubmed

Cho S, Yun S, Jo C, Lee D, Choi K, Song J, et al. SUMO1 promotes Aβ production via the modulation of autophagy. Autophagy. 2015;11:100-12 pubmed 出版商

Bond M, Ghosh S, Wang P, Hanover J. Conserved nutrient sensor O-GlcNAc transferase is integral to C. elegans pathogen-specific immunity. PLoS ONE. 2014;9:e113231 pubmed 出版商

Nakashima H, Nguyen T, Goins W, Chiocca E. Interferon-stimulated gene 15 (ISG15) and ISG15-linked proteins can associate with members of the selective autophagic process, histone deacetylase 6 (HDAC6) and SQSTM1/p62. J Biol Chem. 2015;290:1485-95 pubmed 出版商

Vigelsø A, Dybboe R, Hansen C, Dela F, Helge J, Guadalupe Grau A. GAPDH and β-actin protein decreases with aging, making Stain-Free technology a superior loading control in Western blotting of human skeletal muscle. J Appl Physiol (1985). 2015;118:386-94 pubmed 出版商

Bian W, Miao W, He S, Wan Z, Luo Z, Yu X. A novel Wnt5a-Frizzled4 signaling pathway mediates activity-independent dendrite morphogenesis via the distal PDZ motif of Frizzled 4. Dev Neurobiol. 2015;75:805-22 pubmed 出版商

Carmena M, Lombardía M, Ogawa H, Earnshaw W. Polo kinase regulates the localization and activity of the chromosomal passenger complex in meiosis and mitosis in Drosophila melanogaster. Open Biol. 2014;4:140162 pubmed 出版商

Akoury E, Zhang L, Ao A, Slim R. NLRP7 and KHDC3L, the two maternal-effect proteins responsible for recurrent hydatidiform moles, co-localize to the oocyte cytoskeleton. Hum Reprod. 2015;30:159-69 pubmed 出版商

O Loghlen A, Martin N, Krusche B, Pemberton H, Alonso M, Chandler H, et al. The nuclear receptor NR2E1/TLX controls senescence. Oncogene. 2015;34:4069-4077 pubmed 出版商

Lin Y, Zhang H, Liang J, Li K, Zhu W, Fu L, et al. Identification and characterization of alphavirus M1 as a selective oncolytic virus targeting ZAP-defective human cancers. Proc Natl Acad Sci U S A. 2014;111:E4504-12 pubmed 出版商

Choi J, Park B, Chi S, Bae K, Kim S, Cho S, et al. HAX1 regulates E3 ubiquitin ligase activity of cIAPs by promoting their dimerization. Oncotarget. 2014;5:10084-99 pubmed

Moskwa P, Zinn P, Choi Y, Shukla S, Fendler W, Chen C, et al. A functional screen identifies miRs that induce radioresistance in glioblastomas. Mol Cancer Res. 2014;12:1767-78 pubmed 出版商

Dannappel M, Vlantis K, Kumari S, Polykratis A, Kim C, Wachsmuth L, et al. RIPK1 maintains epithelial homeostasis by inhibiting apoptosis and necroptosis. Nature. 2014;513:90-4 pubmed 出版商

Bazot Q, Deschamps T, Tafforeau L, Siouda M, Leblanc P, Harth Hertle M, et al. Epstein-Barr virus nuclear antigen 3A protein regulates CDKN2B transcription via interaction with MIZ-1. Nucleic Acids Res. 2014;42:9700-16 pubmed 出版商

Vassilopoulos A, Tominaga Y, Kim H, Lahusen T, Li B, Yu H, et al. WEE1 murine deficiency induces hyper-activation of APC/C and results in genomic instability and carcinogenesis. Oncogene. 2015;34:3023-35 pubmed 出版商

Fernandez Vidal A, Guitton Sert L, Cadoret J, Drac M, Schwob E, Baldacci G, et al. A role for DNA polymerase ? in the timing of DNA replication. Nat Commun. 2014;5:4285 pubmed 出版商

Kim C, Pasparakis M. Epidermal p65/NF-?B signalling is essential for skin carcinogenesis. EMBO Mol Med. 2014;6:970-83 pubmed 出版商

Sung P, Murayama A, Kang W, Kim M, Yoon S, Fukasawa M, et al. Hepatitis C virus entry is impaired by claudin-1 downregulation in diacylglycerol acyltransferase-1-deficient cells. J Virol. 2014;88:9233-44 pubmed 出版商

Hans F, Fiesel F, Strong J, J ckel S, Rasse T, Geisler S, et al. UBE2E ubiquitin-conjugating enzymes and ubiquitin isopeptidase Y regulate TDP-43 protein ubiquitination. J Biol Chem. 2014;289:19164-79 pubmed 出版商

Liu J, MCCLELAND M, Stawiski E, Gnad F, Mayba O, Haverty P, et al. Integrated exome and transcriptome sequencing reveals ZAK isoform usage in gastric cancer. Nat Commun. 2014;5:3830 pubmed 出版商

Okada N, Toda T, Yamamoto M, Sato M. CDK-dependent phosphorylation of Alp7-Alp14 (TACC-TOG) promotes its nuclear accumulation and spindle microtubule assembly. Mol Biol Cell. 2014;25:1969-82 pubmed 出版商

Negishi M, Wongpalee S, Sarkar S, Park J, Lee K, Shibata Y, et al. A new lncRNA, APTR, associates with and represses the CDKN1A/p21 promoter by recruiting polycomb proteins. PLoS ONE. 2014;9:e95216 pubmed 出版商

Kiss A, Horvath P, Rothballer A, Kutay U, Csucs G. Nuclear motility in glioma cells reveals a cell-line dependent role of various cytoskeletal components. PLoS ONE. 2014;9:e93431 pubmed 出版商

Meehan A, Saenz D, Guevera R, Morrison J, Peretz M, Fadel H, et al. A cyclophilin homology domain-independent role for Nup358 in HIV-1 infection. PLoS Pathog. 2014;10:e1003969 pubmed 出版商

Khan K, Schneider Poetsch T, Ishfaq M, Ito A, Yoshimoto R, Mukaida N, et al. Splicing inhibition induces gene expression through canonical NF-?B pathway and extracellular signal-related kinase activation. FEBS Lett. 2014;588:1053-7 pubmed 出版商

Gonçalves V, Henriques A, Henriques A, Pereira J, Pereira J, Neves Costa A, et al. Phosphorylation of SRSF1 by SRPK1 regulates alternative splicing of tumor-related Rac1b in colorectal cells. RNA. 2014;20:474-82 pubmed 出版商

Salabei J, Gibb A, Hill B. Comprehensive measurement of respiratory activity in permeabilized cells using extracellular flux analysis. Nat Protoc. 2014;9:421-38 pubmed 出版商

Cheng Y, Holloway M, Nguyen K, McCauley D, Landesman Y, Kauffman M, et al. XPO1 (CRM1) inhibition represses STAT3 activation to drive a survivin-dependent oncogenic switch in triple-negative breast cancer. Mol Cancer Ther. 2014;13:675-86 pubmed 出版商

Li A, Jiao Y, Yong K, Wang F, Gao C, Yan B, et al. SALL4 is a new target in endometrial cancer. Oncogene. 2015;34:63-72 pubmed 出版商

Chu C, Gerstenzang E, Ossipova O, Sokol S. Lulu regulates Shroom-induced apical constriction during neural tube closure. PLoS ONE. 2013;8:e81854 pubmed 出版商

de Poot S, Lai K, van der Wal L, Plasman K, Van Damme P, Porter A, et al. Granzyme M targets topoisomerase II alpha to trigger cell cycle arrest and caspase-dependent apoptosis. Cell Death Differ. 2014;21:416-26 pubmed 出版商

Setyarani M, Zinellu A, Carru C, Zulli A. High dietary taurine inhibits myocardial apoptosis during an atherogenic diet: association with increased myocardial HSP70 and HSF-1 but not caspase 3. Eur J Nutr. 2014;53:929-37 pubmed 出版商

Boutros R, Mondesert O, Lorenzo C, Astuti P, McArthur G, Chircop M, et al. CDC25B overexpression stabilises centrin 2 and promotes the formation of excess centriolar foci. PLoS ONE. 2013;8:e67822 pubmed 出版商

Kolupaeva V, Daempfling L, Basilico C. The B55? regulatory subunit of protein phosphatase 2A mediates fibroblast growth factor-induced p107 dephosphorylation and growth arrest in chondrocytes. Mol Cell Biol. 2013;33:2865-78 pubmed 出版商

Wang Y, Dantas T, Lalor P, Dockery P, Morrison C. Promoter hijack reveals pericentrin functions in mitosis and the DNA damage response. Cell Cycle. 2013;12:635-46 pubmed 出版商

Spiller C, Feng C, Jackson A, Gillis A, Rolland A, Looijenga L, et al. Endogenous Nodal signaling regulates germ cell potency during mammalian testis development. Development. 2012;139:4123-32 pubmed 出版商

Balsas P, Galán Malo P, Marzo I, Naval J. Bortezomib resistance in a myeloma cell line is associated to PSM?5 overexpression and polyploidy. Leuk Res. 2012;36:212-8 pubmed 出版商

Li D, Shin J, Duan D. iNOS ablation does not improve specific force of the extensor digitorum longus muscle in dystrophin-deficient mdx4cv mice. PLoS ONE. 2011;6:e21618 pubmed 出版商

Boichuk S, Hu L, Hein J, Gjoerup O. Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen. J Virol. 2010;84:8007-20 pubmed 出版商

Pandithage R, Lilischkis R, Harting K, Wolf A, Jedamzik B, Lüscher Firzlaff J, et al. The regulation of SIRT2 function by cyclin-dependent kinases affects cell motility. J Cell Biol. 2008;180:915-29 pubmed 出版商

Róna G, Roberti D, Yin Y, Pagan J, Homer H, Sassani E, et al. PARP1-dependent recruitment of the FBXL10-RNF68-RNF2 ubiquitin ligase to sites of DNA damage controls H2A.Z loading. elife. 2018;7: pubmed 出版商

Bütepage M, Preisinger C, von Kriegsheim A, Scheufen A, Lausberg E, Li J, et al. Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription. Sci Rep. 2018;8:6748 pubmed 出版商

Amaya Ramirez C, Hubbe P, Mandel N, Béthune J. 4EHP-independent repression of endogenous mRNAs by the RNA-binding protein GIGYF2. Nucleic Acids Res. 2018;46:5792-5808 pubmed 出版商

Tarbet H, Dolat L, Smith T, Condon B, O Brien E, Valdivia R, et al. Site-specific glycosylation regulates the form and function of the intermediate filament cytoskeleton. elife. 2018;7: pubmed 出版商

Cox N, Unlu G, Bisnett B, Meister T, Condon B, Luo P, et al. Dynamic Glycosylation Governs the Vertebrate COPII Protein Trafficking Pathway. Biochemistry. 2018;57:91-107 pubmed 出版商

Mizoguchi T, Ikeda S, Watanabe S, Sugawara M, Itoh M. Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway. Proc Natl Acad Sci U S A. 2017;114:E9280-E9289 pubmed 出版商

Hamilton L, Acteau G, Xu W, Sutovsky P, Oko R. The developmental origin and compartmentalization of glutathione-s-transferase omega 2 isoforms in the perinuclear theca of eutherian spermatozoa. Biol Reprod. 2017;97:612-621 pubmed 出版商

Song C, Hotz Wagenblatt A, Voit R, Grummt I. SIRT7 and the DEAD-box helicase DDX21 cooperate to resolve genomic R loops and safeguard genome stability. Genes Dev. 2017;31:1370-1381 pubmed 出版商

Skowron M, Niegisch G, Albrecht P, Van Koeveringe G, Romano A, Albers P, et al. Various Mechanisms Involve the Nuclear Factor (Erythroid-Derived 2)-Like (NRF2) to Achieve Cytoprotection in Long-Term Cisplatin-Treated Urothelial Carcinoma Cell Lines. Int J Mol Sci. 2017;18: pubmed 出版商

Auckland P, Clarke N, Royle S, McAinsh A. Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment. J Cell Biol. 2017;216:1623-1639 pubmed 出版商

McRae E, Booy E, Moya Torres A, Ezzati P, Stetefeld J, McKenna S. Human DDX21 binds and unwinds RNA guanine quadruplexes. Nucleic Acids Res. 2017;45:6656-6668 pubmed 出版商

Tawo R, Pokrzywa W, Kevei E, Akyuz M, Balaji V, Adrian S, et al. The Ubiquitin Ligase CHIP Integrates Proteostasis and Aging by Regulation of Insulin Receptor Turnover. Cell. 2017;169:470-482.e13 pubmed 出版商

Blank M, Chen S, Poetz F, Schnolzer M, Voit R, Grummt I. SIRT7-dependent deacetylation of CDK9 activates RNA polymerase II transcription. Nucleic Acids Res. 2017;45:2675-2686 pubmed 出版商

Doshina A, Gourgue F, Onizuka M, Opsomer R, Wang P, Ando K, et al. Cortical cells reveal APP as a new player in the regulation of GABAergic neurotransmission. Sci Rep. 2017;7:370 pubmed 出版商

Leung J, He Y, Zhang F, Hwang Y, Nagayasu E, Liu J, et al. Stability and function of a putative microtubule-organizing center in the human parasite Toxoplasma gondii. Mol Biol Cell. 2017;28:1361-1378 pubmed 出版商

Gama J, Pereira C, Simões P, Celestino R, Reis R, Barbosa D, et al. Molecular mechanism of dynein recruitment to kinetochores by the Rod-Zw10-Zwilch complex and Spindly. J Cell Biol. 2017;216:943-960 pubmed 出版商

Takaoka N, Takayama T, Ozono S. Functional analysis of fatty acid binding protein 7 and its effect on fatty acid of renal cell carcinoma cell lines. BMC Cancer. 2017;17:192 pubmed 出版商

Capitanio J, Montpetit B, Wozniak R. Human Nup98 regulates the localization and activity of DExH/D-box helicase DHX9. elife. 2017;6: pubmed 出版商

Yang W, Campbell M, Chang P. SUMO modification of a heterochromatin histone demethylase JMJD2A enables viral gene transactivation and viral replication. PLoS Pathog. 2017;13:e1006216 pubmed 出版商

Hammerling B, Najor R, Cortez M, Shires S, Leon L, Gonzalez E, et al. A Rab5 endosomal pathway mediates Parkin-dependent mitochondrial clearance. Nat Commun. 2017;8:14050 pubmed 出版商

Flanagan A, Stavenschi E, Basavaraju S, Gaboriau D, Hoey D, Morrison C. Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification. Mol Biol Cell. 2017;28:736-745 pubmed 出版商

Wienholz F, Vermeulen W, Marteijn J. Amplification of unscheduled DNA synthesis signal enables fluorescence-based single cell quantification of transcription-coupled nucleotide excision repair. Nucleic Acids Res. 2017;45:e68 pubmed 出版商

Sansregret L, Patterson J, Dewhurst S, Lopez Garcia C, Koch A, McGranahan N, et al. APC/C Dysfunction Limits Excessive Cancer Chromosomal Instability. Cancer Discov. 2017;7:218-233 pubmed 出版商

Lehmann S, Loh S, Martins L. Enhancing NAD+ salvage metabolism is neuroprotective in a PINK1 model of Parkinson's disease. Biol Open. 2017;6:141-147 pubmed 出版商

Stoney P, Rodrigues D, Helfer G, Khatib T, Ashton A, Hay E, et al. A seasonal switch in histone deacetylase gene expression in the hypothalamus and their capacity to modulate nuclear signaling pathways. Brain Behav Immun. 2017;61:340-352 pubmed 出版商

Hörnberg H, Cioni J, Harris W, Holt C. Hermes Regulates Axon Sorting in the Optic Tract by Post-Trancriptional Regulation of Neuropilin 1. J Neurosci. 2016;36:12697-12706 pubmed

Kaufmann T, Kukolj E, Brachner A, Beltzung E, Bruno M, Kostrhon S, et al. SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation. J Cell Sci. 2016;129:4607-4621 pubmed

Geiger R, Rieckmann J, Wolf T, Basso C, Feng Y, Fuhrer T, et al. L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity. Cell. 2016;167:829-842.e13 pubmed 出版商

Ustianenko D, Pasulka J, Feketova Z, Bednarik L, Zigackova D, Fortova A, et al. TUT-DIS3L2 is a mammalian surveillance pathway for aberrant structured non-coding RNAs. EMBO J. 2016;35:2179-2191 pubmed

Xia L, Tang Y, Song F, Xu L, Ji P, Wang S, et al. DCTPP1 attenuates the sensitivity of human gastric cancer cells to 5-fluorouracil by up-regulating MDR1 expression epigenetically. Oncotarget. 2016;7:68623-68637 pubmed 出版商

Weber A, Drobnitzky N, Devery A, Bokobza S, Adams R, Maughan T, et al. Phenotypic consequences of somatic mutations in the ataxia-telangiectasia mutated gene in non-small cell lung cancer. Oncotarget. 2016;7:60807-60822 pubmed 出版商

Bultot L, Jensen T, Lai Y, Madsen A, Collodet C, Kviklyte S, et al. Benzimidazole derivative small-molecule 991 enhances AMPK activity and glucose uptake induced by AICAR or contraction in skeletal muscle. Am J Physiol Endocrinol Metab. 2016;311:E706-E719 pubmed 出版商

Velinder M, Singer J, Bareyan D, Meznarich J, Tracy C, Fulcher J, et al. GFI1 functions in transcriptional control and cell fate determination require SNAG domain methylation to recruit LSD1. Biochem J. 2016;473:3355-69 pubmed 出版商

Lofruthe N, Gallitz I, Traeger L, Baumer N, Schulze I, Kuhlmann T, et al. Intravenous Iron Carboxymaltose as a Potential Therapeutic in Anemia of Inflammation. PLoS ONE. 2016;11:e0158599 pubmed 出版商

Djavadian R, Chiu Y, Johannsen E. An Epstein-Barr Virus-Encoded Protein Complex Requires an Origin of Lytic Replication In Cis to Mediate Late Gene Transcription. PLoS Pathog. 2016;12:e1005718 pubmed 出版商

Ruiz Martinez M, Navarro A, Marrades R, Viñolas N, Santasusagna S, Muñoz C, et al. YKT6 expression, exosome release, and survival in non-small cell lung cancer. Oncotarget. 2016;7:51515-51524 pubmed 出版商

Polacchini A, Albani C, Baj G, Colliva A, Carpinelli P, Tongiorgi E. Combined cisplatin and aurora inhibitor treatment increase neuroblastoma cell death but surviving cells overproduce BDNF. Biol Open. 2016;5:899-907 pubmed 出版商

Shirakawa K, Wang L, Man N, Maksimoska J, Sorum A, Lim H, et al. Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity. elife. 2016;5: pubmed 出版商

Pandolfini L, Luzi E, Bressan D, Ucciferri N, Bertacchi M, Brandi R, et al. RISC-mediated control of selected chromatin regulators stabilizes ground state pluripotency of mouse embryonic stem cells. Genome Biol. 2016;17:94 pubmed 出版商

Niu D, Lii Y, Chellappan P, Lei L, Peralta K, Jiang C, et al. miRNA863-3p sequentially targets negative immune regulator ARLPKs and positive regulator SERRATE upon bacterial infection. Nat Commun. 2016;7:11324 pubmed 出版商

Buck S, Maqani N, Matecic M, Hontz R, Fine R, Li M, et al. RNA Polymerase I and Fob1 contributions to transcriptional silencing at the yeast rDNA locus. Nucleic Acids Res. 2016;44:6173-84 pubmed 出版商

Caron M, Emans P, Sanen K, Surtel D, Cremers A, Ophelders D, et al. The Role of Prostaglandins and COX-Enzymes in Chondrogenic Differentiation of ATDC5 Progenitor Cells. PLoS ONE. 2016;11:e0153162 pubmed 出版商

Lehmann S, Costa A, Celardo I, Loh S, Martins L. Parp mutations protect against mitochondrial dysfunction and neurodegeneration in a PARKIN model of Parkinson's disease. Cell Death Dis. 2016;7:e2166 pubmed 出版商

Kim H, Choi S, Yoon J, Lim H, Lee H, Choi J, et al. Small molecule inhibitors of the Dishevelled-CXXC5 interaction are new drug candidates for bone anabolic osteoporosis therapy. EMBO Mol Med. 2016;8:375-87 pubmed 出版商

Datan E, Roy S, Germain G, Zali N, McLean J, Golshan G, et al. Dengue-induced autophagy, virus replication and protection from cell death require ER stress (PERK) pathway activation. Cell Death Dis. 2016;7:e2127 pubmed 出版商

Martino Echarri E, Brocardo M, Mills K, Henderson B. Tankyrase Inhibitors Stimulate the Ability of Tankyrases to Bind Axin and Drive Assembly of β-Catenin Degradation-Competent Axin Puncta. PLoS ONE. 2016;11:e0150484 pubmed 出版商

Ren Z, Veksler Lublinsky I, Morrissey D, Ambros V. Staufen Negatively Modulates MicroRNA Activity in Caenorhabditis elegans. G3 (Bethesda). 2016;6:1227-37 pubmed 出版商

Badr H, Kozai D, Sakaguchi R, Numata T, Mori Y. Different Contribution of Redox-Sensitive Transient Receptor Potential Channels to Acetaminophen-Induced Death of Human Hepatoma Cell Line. Front Pharmacol. 2016;7:19 pubmed 出版商

Lee M, McGeer E, McGeer P. Sodium thiosulfate attenuates glial-mediated neuroinflammation in degenerative neurological diseases. J Neuroinflammation. 2016;13:32 pubmed 出版商

Zhang Y, Liu C, Barbier O, Smalling R, Tsuchiya H, Lee S, et al. Bcl2 is a critical regulator of bile acid homeostasis by dictating Shp and lncRNA H19 function. Sci Rep. 2016;6:20559 pubmed 出版商

van den Akker G, Surtel D, Cremers A, Richardson S, Hoyland J, van Rhijn L, et al. Novel Immortal Cell Lines Support Cellular Heterogeneity in the Human Annulus Fibrosus. PLoS ONE. 2016;11:e0144497 pubmed 出版商

Escobar H, Schöwel V, Spuler S, Marg A, Izsvák Z. Full-length Dysferlin Transfer by the Hyperactive Sleeping Beauty Transposase Restores Dysferlin-deficient Muscle. Mol Ther Nucleic Acids. 2016;5:e277 pubmed 出版商

Tognon E, Kobia F, Busi I, Fumagalli A, De Masi F, Vaccari T. Control of lysosomal biogenesis and Notch-dependent tissue patterning by components of the TFEB-V-ATPase axis in Drosophila melanogaster. Autophagy. 2016;12:499-514 pubmed 出版商

Liu J, He Y, Benmerzouga I, Sullivan W, Morrissette N, Murray J, et al. An ensemble of specifically targeted proteins stabilizes cortical microtubules in the human parasite Toxoplasma gondii. Mol Biol Cell. 2016;27:549-71 pubmed 出版商

Chen J, Chen Y, Yen C, Chen W, Huang W. HBx sensitizes hepatocellular carcinoma cells to lapatinib by up-regulating ErbB3. Oncotarget. 2016;7:473-89 pubmed 出版商

Kozlova N, Samoylenko A, Drobot L, Kietzmann T. Urokinase is a negative modulator of Egf-dependent proliferation and motility in the two breast cancer cell lines MCF-7 and MDA-MB-231. Mol Carcinog. 2016;55:170-81 pubmed 出版商

Patel J, Tan S, Hartshorne G, McAinsh A. Unique geometry of sister kinetochores in human oocytes during meiosis I may explain maternal age-associated increases in chromosomal abnormalities. Biol Open. 2015;5:178-84 pubmed 出版商

Carbotti G, Barisione G, Airoldi I, Mezzanzanica D, Bagnoli M, Ferrero S, et al. IL-27 induces the expression of IDO and PD-L1 in human cancer cells. Oncotarget. 2015;6:43267-80 pubmed 出版商

Dong B, Yang X, Zhu S, Bassham D, Fang N. Stochastic Optical Reconstruction Microscopy Imaging of Microtubule Arrays in Intact Arabidopsis thaliana Seedling Roots. Sci Rep. 2015;5:15694 pubmed 出版商

Bollard J, Massoma P, Vercherat C, Blanc M, Lepinasse F, Gadot N, et al. The axon guidance molecule semaphorin 3F is a negative regulator of tumor progression and proliferation in ileal neuroendocrine tumors. Oncotarget. 2015;6:36731-45 pubmed 出版商

Leyme A, Marivin A, Perez Gutierrez L, Nguyen L, Garcia Marcos M. Integrins activate trimeric G proteins via the nonreceptor protein GIV/Girdin. J Cell Biol. 2015;210:1165-84 pubmed 出版商

Zhuo X, Guo X, Zhang X, Jing G, Wang Y, Chen Q, et al. Usp16 regulates kinetochore localization of Plk1 to promote proper chromosome alignment in mitosis. J Cell Biol. 2015;210:727-35 pubmed 出版商

Xue R, Lynes M, Dreyfuss J, Shamsi F, Schulz T, Zhang H, et al. Clonal analyses and gene profiling identify genetic biomarkers of the thermogenic potential of human brown and white preadipocytes. Nat Med. 2015;21:760-8 pubmed 出版商

Ruiz M, Alvarez M, Eirín López J, Sarno F, Kremer L, Barbero J, et al. An Unusual Role for doublesex in Sex Determination in the Dipteran Sciara. Genetics. 2015;200:1181-99 pubmed 出版商

Xiao C, Goldgof M, Gavrilova O, Reitman M. Anti-obesity and metabolic efficacy of the β3-adrenergic agonist, CL316243, in mice at thermoneutrality compared to 22°C. Obesity (Silver Spring). 2015;23:1450-9 pubmed 出版商

Milan E, Perini T, Resnati M, Orfanelli U, Oliva L, Raimondi A, et al. A plastic SQSTM1/p62-dependent autophagic reserve maintains proteostasis and determines proteasome inhibitor susceptibility in multiple myeloma cells. Autophagy. 2015;11:1161-78 pubmed 出版商

Fellmeth J, Gordon D, Robins C, Scott R, Treff N, Schindler K. Expression and characterization of three Aurora kinase C splice variants found in human oocytes. Mol Hum Reprod. 2015;21:633-44 pubmed 出版商

Nieuwenhuizen R, Bates M, Szymborska A, Lidke K, Rieger B, Stallinga S. Quantitative localization microscopy: effects of photophysics and labeling stoichiometry. PLoS ONE. 2015;10:e0127989 pubmed 出版商

Verheyen T, Görnemann J, Verbinnen I, Boens S, Beullens M, Van Eynde A, et al. Genome-wide promoter binding profiling of protein phosphatase-1 and its major nuclear targeting subunits. Nucleic Acids Res. 2015;43:5771-84 pubmed 出版商

Valley C, Liu S, Lidke D, Lidke K. Sequential superresolution imaging of multiple targets using a single fluorophore. PLoS ONE. 2015;10:e0123941 pubmed 出版商

Obenauf A, Zou Y, Ji A, Vanharanta S, Shu W, Shi H, et al. Therapy-induced tumour secretomes promote resistance and tumour progression. Nature. 2015;520:368-72 pubmed 出版商

Franz H, Greschik H, Willmann D, Ozretić L, Jilg C, Wardelmann E, et al. The histone code reader SPIN1 controls RET signaling in liposarcoma. Oncotarget. 2015;6:4773-89 pubmed

Matsuda T, Yanase S, Takaoka A, Maruyama M. The immunosenescence-related gene Zizimin2 is associated with early bone marrow B cell development and marginal zone B cell formation. Immun Ageing. 2015;12:1 pubmed 出版商

Goldmacher V, Audette C, Guan Y, Sidhom E, Shah J, Whiteman K, et al. High-affinity accumulation of a maytansinoid in cells via weak tubulin interaction. PLoS ONE. 2015;10:e0117523 pubmed 出版商

Wang H, Zhang H, Zhang J, Li Y, Zhao B, Feng G, et al. Neuropilin 1 is an entry factor that promotes EBV infection of nasopharyngeal epithelial cells. Nat Commun. 2015;6:6240 pubmed 出版商

Chen X, Wales P, Quinti L, Zuo F, Moniot S, Herisson F, et al. The sirtuin-2 inhibitor AK7 is neuroprotective in models of Parkinson's disease but not amyotrophic lateral sclerosis and cerebral ischemia. PLoS ONE. 2015;10:e0116919 pubmed 出版商

Marschall A, Single F, Schlarmann K, Bosio A, Strebe N, van den Heuvel J, et al. Functional knock down of VCAM1 in mice mediated by endoplasmatic reticulum retained intrabodies. MAbs. 2014;6:1394-401 pubmed 出版商

Lelliott C, Ahnmark A, Admyre T, Ahlstedt I, Irving L, Keyes F, et al. Monoclonal antibody targeting of fibroblast growth factor receptor 1c ameliorates obesity and glucose intolerance via central mechanisms. PLoS ONE. 2014;9:e112109 pubmed 出版商

Zhang X, Niu D, Carbonell A, Wang A, Lee A, Tun V, et al. ARGONAUTE PIWI domain and microRNA duplex structure regulate small RNA sorting in Arabidopsis. Nat Commun. 2014;5:5468 pubmed 出版商

Tan Y, Kim M, Kingsbury T, Civin C, Cheng W. Regulation of RAB5C is important for the growth inhibitory effects of MiR-509 in human precursor-B acute lymphoblastic leukemia. PLoS ONE. 2014;9:e111777 pubmed 出版商

Cheng H, Xu X, Hadfield T, Cockett N, Charlier C, Georges M, et al. Experimental evaluation does not reveal a direct effect of microRNA from the callipyge locus on DLK1 expression. BMC Genomics. 2014;15:944 pubmed 出版商

Martin C, Ahmad I, Klingseisen A, Hussain M, Bicknell L, Leitch A, et al. Mutations in PLK4, encoding a master regulator of centriole biogenesis, cause microcephaly, growth failure and retinopathy. Nat Genet. 2014;46:1283-1292 pubmed 出版商

Horbach T, Chi T, Götz C, Sharma S, Juffer A, Dimova E, et al. GSK3β-dependent phosphorylation alters DNA binding, transactivity and half-life of the transcription factor USF2. PLoS ONE. 2014;9:e107914 pubmed 出版商

Sastre Moreno G, Sánchez A, Esteban V, Blanco L. ATP insertion opposite 8-oxo-deoxyguanosine by Pol4 mediates error-free tolerance in Schizosaccharomyces pombe. Nucleic Acids Res. 2014;42:9821-37 pubmed 出版商

Guan D, Lim J, Peng L, Liu Y, Lam M, Seto E, et al. Deacetylation of the tumor suppressor protein PML regulates hydrogen peroxide-induced cell death. Cell Death Dis. 2014;5:e1340 pubmed 出版商

Geng S, De Hoff P, Umen J. Evolution of sexes from an ancestral mating-type specification pathway. PLoS Biol. 2014;12:e1001904 pubmed 出版商

van den Akker G, Surtel D, Cremers A, Rodrigues Pinto R, Richardson S, Hoyland J, et al. Novel immortal human cell lines reveal subpopulations in the nucleus pulposus. Arthritis Res Ther. 2014;16:R135 pubmed 出版商

Odendall C, Dixit E, Stavru F, Bierne H, Franz K, Durbin A, et al. Diverse intracellular pathogens activate type III interferon expression from peroxisomes. Nat Immunol. 2014;15:717-26 pubmed 出版商

Wu J, Wang Y, Liang S, Ma H. Cytoprotective effect of selective small-molecule caspase inhibitors against staurosporine-induced apoptosis. Drug Des Devel Ther. 2014;8:583-600 pubmed 出版商

Duteil D, Metzger E, Willmann D, Karagianni P, Friedrichs N, Greschik H, et al. LSD1 promotes oxidative metabolism of white adipose tissue. Nat Commun. 2014;5:4093 pubmed 出版商

Wagner S, Herrmannová A, Malik R, Peclinovská L, Valášek L. Functional and biochemical characterization of human eukaryotic translation initiation factor 3 in living cells. Mol Cell Biol. 2014;34:3041-52 pubmed 出版商

Nicot A, Lo Verso F, Ratti F, Pilot Storck F, Streichenberger N, Sandri M, et al. Phosphorylation of NBR1 by GSK3 modulates protein aggregation. Autophagy. 2014;10:1036-53 pubmed 出版商

Ganassi M, Badodi S, Polacchini A, Baruffaldi F, Battini R, Hughes S, et al. Distinct functions of alternatively spliced isoforms encoded by zebrafish mef2ca and mef2cb. Biochim Biophys Acta. 2014;1839:559-70 pubmed 出版商

Renga B, Francisci D, Schiaroli E, Carino A, Cipriani S, D Amore C, et al. The HIV matrix protein p17 promotes the activation of human hepatic stellate cells through interactions with CXCR2 and Syndecan-2. PLoS ONE. 2014;9:e94798 pubmed 出版商

Ray S, Li H, Metzger E, Schüle R, Leiter A. CtBP and associated LSD1 are required for transcriptional activation by NeuroD1 in gastrointestinal endocrine cells. Mol Cell Biol. 2014;34:2308-17 pubmed 出版商

Wang B, Rao Y, Inoue M, Hao R, Lai C, Chen D, et al. Microtubule acetylation amplifies p38 kinase signalling and anti-inflammatory IL-10 production. Nat Commun. 2014;5:3479 pubmed 出版商

Balboula A, Schindler K. Selective disruption of aurora C kinase reveals distinct functions from aurora B kinase during meiosis in mouse oocytes. PLoS Genet. 2014;10:e1004194 pubmed 出版商

Ramkhelawon B, Hennessy E, Ménager M, Ray T, Sheedy F, Hutchison S, et al. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity. Nat Med. 2014;20:377-84 pubmed 出版商

Chalupníková K, Solc P, Sulimenko V, Sedlacek R, Svoboda P. An oocyte-specific ELAVL2 isoform is a translational repressor ablated from meiotically competent antral oocytes. Cell Cycle. 2014;13:1187-200 pubmed 出版商

Komolka K, Albrecht E, Schering L, Brenmoehl J, Hoeflich A, Maak S. Locus characterization and gene expression of bovine FNDC5: is the myokine irisin relevant in cattle?. PLoS ONE. 2014;9:e88060 pubmed 出版商

Lou P, Lucchinetti E, Zhang L, Affolter A, Schaub M, Gandhi M, et al. The mechanism of Intralipid®-mediated cardioprotection complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases. PLoS ONE. 2014;9:e87205 pubmed 出版商

Nejepinska J, Malik R, Wagner S, Svoboda P. Reporters transiently transfected into mammalian cells are highly sensitive to translational repression induced by dsRNA expression. PLoS ONE. 2014;9:e87517 pubmed 出版商

Zhou H, Ge Y, Sun L, Ma W, Wu J, Zhang X, et al. Growth arrest specific 2 is up-regulated in chronic myeloid leukemia cells and required for their growth. PLoS ONE. 2014;9:e86195 pubmed 出版商

Henning M, Dubose B, Burse M, Aiken C, Yamashita M. In vivo functions of CPSF6 for HIV-1 as revealed by HIV-1 capsid evolution in HLA-B27-positive subjects. PLoS Pathog. 2014;10:e1003868 pubmed 出版商

Bershteyn M, Hayashi Y, Desachy G, Hsiao E, Sami S, Tsang K, et al. Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells. Nature. 2014;507:99-103 pubmed 出版商

Booy E, Howard R, Marushchak O, Ariyo E, Meier M, Novakowski S, et al. The RNA helicase RHAU (DHX36) suppresses expression of the transcription factor PITX1. Nucleic Acids Res. 2014;42:3346-61 pubmed 出版商

Liu S, Wang H, Tang J, Zhou X. Hypoxia-induced collagen synthesis of human lung fibroblasts by activating the angiotensin system. Int J Mol Sci. 2013;14:24029-45 pubmed 出版商

Archambaud C, Sismeiro O, Toedling J, Soubigou G, Bécavin C, Lechat P, et al. The intestinal microbiota interferes with the microRNA response upon oral Listeria infection. MBio. 2013;4:e00707-13 pubmed 出版商

McGirt L, Adams C, Baerenwald D, Zwerner J, Zic J, Eischen C. miR-223 regulates cell growth and targets proto-oncogenes in mycosis fungoides/cutaneous T-cell lymphoma. J Invest Dermatol. 2014;134:1101-1107 pubmed 出版商

Gallego Paez L, Tanaka H, Bando M, Takahashi M, Nozaki N, Nakato R, et al. Smc5/6-mediated regulation of replication progression contributes to chromosome assembly during mitosis in human cells. Mol Biol Cell. 2014;25:302-17 pubmed 出版商

Barboro P, Borzi L, Repaci E, Ferrari N, Balbi C. Androgen receptor activity is affected by both nuclear matrix localization and the phosphorylation status of the heterogeneous nuclear ribonucleoprotein K in anti-androgen-treated LNCaP cells. PLoS ONE. 2013;8:e79212 pubmed 出版商

Nakano M, Nakashima A, Nagano T, Ishikawa S, Kikkawa U, Kamada S. Branched-chain amino acids enhance premature senescence through mammalian target of rapamycin complex I-mediated upregulation of p21 protein. PLoS ONE. 2013;8:e80411 pubmed 出版商

Rocchiccioli S, Pelosi G, Rosini S, Marconi M, Viglione F, Citti L, et al. Secreted proteins from carotid endarterectomy: an untargeted approach to disclose molecular clues of plaque progression. J Transl Med. 2013;11:260 pubmed 出版商

Mitchell C, Churchward Venne T, Bellamy L, Parise G, Baker S, Phillips S. Muscular and systemic correlates of resistance training-induced muscle hypertrophy. PLoS ONE. 2013;8:e78636 pubmed 出版商

Jang B, Choi B, Kim J, Kim M, Sohn M, Suh S. Impairment of autophagic flux promotes glucose reperfusion-induced neuro2A cell death after glucose deprivation. PLoS ONE. 2013;8:e76466 pubmed 出版商

Barton K, Misuraca K, Cordero F, Dobrikova E, Min H, Gromeier M, et al. PD-0332991, a CDK4/6 inhibitor, significantly prolongs survival in a genetically engineered mouse model of brainstem glioma. PLoS ONE. 2013;8:e77639 pubmed 出版商

Huang V, Zheng J, Qi Z, Wang J, Place R, Yu J, et al. Ago1 Interacts with RNA polymerase II and binds to the promoters of actively transcribed genes in human cancer cells. PLoS Genet. 2013;9:e1003821 pubmed 出版商

Balmer D, Emery M, Andreux P, Auwerx J, Ginet V, Puyal J, et al. Autophagy defect is associated with low glucose-induced apoptosis in 661W photoreceptor cells. PLoS ONE. 2013;8:e74162 pubmed 出版商

Soler A, Serra H, Pearce W, Angulo A, Guillermet Guibert J, Friedman L, et al. Inhibition of the p110? isoform of PI 3-kinase stimulates nonfunctional tumor angiogenesis. J Exp Med. 2013;210:1937-45 pubmed 出版商

Rieusset A, Schaller F, Unmehopa U, Matarazzo V, Watrin F, Linke M, et al. Stochastic loss of silencing of the imprinted Ndn/NDN allele, in a mouse model and humans with prader-willi syndrome, has functional consequences. PLoS Genet. 2013;9:e1003752 pubmed 出版商

Toth A, Terauchi A, Zhang L, Johnson Venkatesh E, Larsen D, Sutton M, et al. Synapse maturation by activity-dependent ectodomain shedding of SIRPα. Nat Neurosci. 2013;16:1417-25 pubmed 出版商

Ouellet D, Vigneault Edwards J, Létourneau K, Gobeil L, Plante I, Burnett J, et al. Regulation of host gene expression by HIV-1 TAR microRNAs. Retrovirology. 2013;10:86 pubmed 出版商

Ma T, Trinh M, Wexler A, Bourbon C, Gatti E, Pierre P, et al. Suppression of eIF2? kinases alleviates Alzheimer's disease-related plasticity and memory deficits. Nat Neurosci. 2013;16:1299-305 pubmed 出版商

Belluti S, Basile V, Benatti P, Ferrari E, Marverti G, Imbriano C. Concurrent inhibition of enzymatic activity and NF-Y-mediated transcription of Topoisomerase-II? by bis-DemethoxyCurcumin in cancer cells. Cell Death Dis. 2013;4:e756 pubmed 出版商

Singh K, Wachsmuth L, Kulozik A, Gehring N. Two mammalian MAGOH genes contribute to exon junction complex composition and nonsense-mediated decay. RNA Biol. 2013;10:1291-8 pubmed 出版商

Zhou W, Geng Z, Spence J, Geng J. Induction of intestinal stem cells by R-spondin 1 and Slit2 augments chemoradioprotection. Nature. 2013;501:107-11 pubmed 出版商

Caligiuri I, Toffoli G, Giordano A, Rizzolio F. pRb controls estrogen receptor alpha protein stability and activity. Oncotarget. 2013;4:875-83 pubmed

Lai Z, Moravcová S, Canitrot Y, Andrzejewski L, Walshe D, Rea S. Msl2 is a novel component of the vertebrate DNA damage response. PLoS ONE. 2013;8:e68549 pubmed 出版商

Sosanya N, Huang P, Cacheaux L, Chen C, Nguyen K, Perrone Bizzozero N, et al. Degradation of high affinity HuD targets releases Kv1.1 mRNA from miR-129 repression by mTORC1. J Cell Biol. 2013;202:53-69 pubmed 出版商

Bianchi M, Crinelli R, Giacomini E, Carloni E, Radici L, Magnani M. Yin Yang 1 intronic binding sequences and splicing elicit intron-mediated enhancement of ubiquitin C gene expression. PLoS ONE. 2013;8:e65932 pubmed 出版商

Nishi R, Sakai W, Tone D, Hanaoka F, Sugasawa K. Structure-function analysis of the EF-hand protein centrin-2 for its intracellular localization and nucleotide excision repair. Nucleic Acids Res. 2013;41:6917-29 pubmed 出版商

Fang L, Zhou Y, Cao H, Wen P, Jiang L, He W, et al. Autophagy attenuates diabetic glomerular damage through protection of hyperglycemia-induced podocyte injury. PLoS ONE. 2013;8:e60546 pubmed 出版商

Dufour J, Pommier A, Alves G, de Boussac H, Lours Calet C, Volle D, et al. Lack of liver X receptors leads to cell proliferation in a model of mouse dorsal prostate epithelial cell. PLoS ONE. 2013;8:e58876 pubmed 出版商

BURRELL R, McClelland S, Endesfelder D, Groth P, Weller M, Shaikh N, et al. Replication stress links structural and numerical cancer chromosomal instability. Nature. 2013;494:492-496 pubmed 出版商

Zuleger N, Boyle S, Kelly D, de las Heras J, Lazou V, Korfali N, et al. Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery. Genome Biol. 2013;14:R14 pubmed 出版商

Park D, Jung J, Masjkur J, Makrogkikas S, Ebermann D, Saha S, et al. Hes3 regulates cell number in cultures from glioblastoma multiforme with stem cell characteristics. Sci Rep. 2013;3:1095 pubmed 出版商

Lucchetti C, Caligiuri I, Toffoli G, Giordano A, Rizzolio F. The prolyl isomerase Pin1 acts synergistically with CDK2 to regulate the basal activity of estrogen receptor ? in breast cancer. PLoS ONE. 2013;8:e55355 pubmed 出版商

Barbone D, Cheung P, Battula S, Busacca S, Gray S, Longley D, et al. Vorinostat eliminates multicellular resistance of mesothelioma 3D spheroids via restoration of Noxa expression. PLoS ONE. 2012;7:e52753 pubmed 出版商

Mary C, Duek P, Salleron L, Tienz P, Bumann D, Bairoch A, et al. Functional identification of APIP as human mtnB, a key enzyme in the methionine salvage pathway. PLoS ONE. 2012;7:e52877 pubmed 出版商

Togtema M, Pichardo S, Jackson R, Lambert P, Curiel L, Zehbe I. Sonoporation delivery of monoclonal antibodies against human papillomavirus 16 E6 restores p53 expression in transformed cervical keratinocytes. PLoS ONE. 2012;7:e50730 pubmed 出版商

McColl G, Roberts B, Pukala T, Kenche V, Roberts C, Link C, et al. Utility of an improved model of amyloid-beta (A?????) toxicity in Caenorhabditis elegans for drug screening for Alzheimer's disease. Mol Neurodegener. 2012;7:57 pubmed 出版商

Llorente J, Lowe J, Sanderson H, Tsisanova E, Kelly E, Henderson G, et al. ?-Opioid receptor desensitization: homologous or heterologous?. Eur J Neurosci. 2012;36:3636-42 pubmed 出版商

Eschenbacher W, Song M, Chen Y, Bhandari P, Zhao P, Jowdy C, et al. Two rare human mitofusin 2 mutations alter mitochondrial dynamics and induce retinal and cardiac pathology in Drosophila. PLoS ONE. 2012;7:e44296 pubmed 出版商

Feichtinger J, Aldeailej I, Anderson R, Almutairi M, Almatrafi A, Alsiwiehri N, et al. Meta-analysis of clinical data using human meiotic genes identifies a novel cohort of highly restricted cancer-specific marker genes. Oncotarget. 2012;3:843-53 pubmed

Haaß W, Stehle M, Nittka S, Giehl M, Schrotz King P, Fabarius A, et al. The proteolytic activity of separase in BCR-ABL-positive cells is increased by imatinib. PLoS ONE. 2012;7:e42863 pubmed 出版商

Shin J, Padmanabhan A, de Groh E, Lee J, Haidar S, Dahlberg S, et al. Zebrafish neurofibromatosis type 1 genes have redundant functions in tumorigenesis and embryonic development. Dis Model Mech. 2012;5:881-94 pubmed 出版商

Barros P, Lam E, Jordan P, Matos P. Rac1 signalling modulates a STAT5/BCL-6 transcriptional switch on cell-cycle-associated target gene promoters. Nucleic Acids Res. 2012;40:7776-87 pubmed 出版商

Perez Mancera P, Rust A, van der Weyden L, Kristiansen G, Li A, Sarver A, et al. The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma. Nature. 2012;486:266-70 pubmed 出版商

Hashimoto T, Juso K, Nakano M, Nagano T, Kambayashi S, Nakashima A, et al. Preferential Fas-mediated apoptotic execution at G1 phase: the resistance of mitotic cells to the cell death. Cell Death Dis. 2012;3:e313 pubmed 出版商

Gorges T, Tinhofer I, Drosch M, Rose L, Zollner T, Krahn T, et al. Circulating tumour cells escape from EpCAM-based detection due to epithelial-to-mesenchymal transition. BMC Cancer. 2012;12:178 pubmed 出版商

Sánchez Danés A, Richaud Patin Y, Carballo Carbajal I, Jimenez Delgado S, Caig C, Mora S, et al. Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease. EMBO Mol Med. 2012;4:380-95 pubmed 出版商

Dietrich N, Lerdrup M, Landt E, Agrawal Singh S, Bak M, Tommerup N, et al. REST-mediated recruitment of polycomb repressor complexes in mammalian cells. PLoS Genet. 2012;8:e1002494 pubmed 出版商

Wills J, Credle J, Oaks A, Duka V, Lee J, Jones J, et al. Paraquat, but not maneb, induces synucleinopathy and tauopathy in striata of mice through inhibition of proteasomal and autophagic pathways. PLoS ONE. 2012;7:e30745 pubmed 出版商

Clements E, Mohammad H, Leadem B, Easwaran H, Cai Y, Van Neste L, et al. DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes. Nucleic Acids Res. 2012;40:4334-46 pubmed 出版商

Booy E, Meier M, Okun N, Novakowski S, Xiong S, Stetefeld J, et al. The RNA helicase RHAU (DHX36) unwinds a G4-quadruplex in human telomerase RNA and promotes the formation of the P1 helix template boundary. Nucleic Acids Res. 2012;40:4110-24 pubmed 出版商

Siaud N, Barbera M, Egashira A, Lam I, Christ N, Schlacher K, et al. Plasticity of BRCA2 function in homologous recombination: genetic interactions of the PALB2 and DNA binding domains. PLoS Genet. 2011;7:e1002409 pubmed 出版商

Pivetta E, Scapolan M, Pecolo M, Wassermann B, Abu Rumeileh I, Balestreri L, et al. MMP-13 stimulates osteoclast differentiation and activation in tumour breast bone metastases. Breast Cancer Res. 2011;13:R105 pubmed 出版商

Ehlken H, Kondylis V, Heinrichsdorff J, Ochoa Callejero L, Roskams T, Pasparakis M. Hepatocyte IKK2 protects Mdr2-/- mice from chronic liver failure. PLoS ONE. 2011;6:e25942 pubmed 出版商

Heaslip A, Nishi M, Stein B, Hu K. The motility of a human parasite, Toxoplasma gondii, is regulated by a novel lysine methyltransferase. PLoS Pathog. 2011;7:e1002201 pubmed 出版商

Sakane N, Kwon H, Pagans S, Kaehlcke K, Mizusawa Y, Kamada M, et al. Activation of HIV transcription by the viral Tat protein requires a demethylation step mediated by lysine-specific demethylase 1 (LSD1/KDM1). PLoS Pathog. 2011;7:e1002184 pubmed 出版商

Weinkopff T, Lammie P. Lack of evidence for the direct activation of endothelial cells by adult female and microfilarial excretory-secretory products. PLoS ONE. 2011;6:e22282 pubmed 出版商

Kaul T, Credle J, Haggerty T, Oaks A, Masliah E, Sidhu A. Region-specific tauopathy and synucleinopathy in brain of the alpha-synuclein overexpressing mouse model of Parkinson's disease. BMC Neurosci. 2011;12:79 pubmed 出版商

Takaoka N, Takayama T, Teratani T, Sugiyama T, Mugiya S, Ozono S. Analysis of the regulation of fatty acid binding protein 7 expression in human renal carcinoma cell lines. BMC Mol Biol. 2011;12:31 pubmed 出版商

Mendoza Maldonado R, Faoro V, Bajpai S, Berti M, Odreman F, Vindigni M, et al. The human RECQ1 helicase is highly expressed in glioblastoma and plays an important role in tumor cell proliferation. Mol Cancer. 2011;10:83 pubmed 出版商

Karicheva O, Kolesnikova O, Schirtz T, Vysokikh M, Mager Heckel A, Lombes A, et al. Correction of the consequences of mitochondrial 3243A>G mutation in the MT-TL1 gene causing the MELAS syndrome by tRNA import into mitochondria. Nucleic Acids Res. 2011;39:8173-86 pubmed 出版商

Barbone D, Ryan J, Kolhatkar N, Chacko A, Jablons D, Sugarbaker D, et al. The Bcl-2 repertoire of mesothelioma spheroids underlies acquired apoptotic multicellular resistance. Cell Death Dis. 2011;2:e174 pubmed 出版商

Kardakaris R, Gareus R, Xanthoulea S, Pasparakis M. Endothelial and macrophage-specific deficiency of P38? MAPK does not affect the pathogenesis of atherosclerosis in ApoE-/- mice. PLoS ONE. 2011;6:e21055 pubmed 出版商

Lancaster M, Gopal D, Kim J, Saleem S, Silhavy J, Louie C, et al. Defective Wnt-dependent cerebellar midline fusion in a mouse model of Joubert syndrome. Nat Med. 2011;17:726-31 pubmed 出版商

Lancaster M, Schroth J, Gleeson J. Subcellular spatial regulation of canonical Wnt signalling at the primary cilium. Nat Cell Biol. 2011;13:700-7 pubmed 出版商

Hashimoto T, Kikkawa U, Kamada S. Contribution of caspase(s) to the cell cycle regulation at mitotic phase. PLoS ONE. 2011;6:e18449 pubmed 出版商

Wills J, Credle J, Haggerty T, Lee J, Oaks A, Sidhu A. Tauopathic changes in the striatum of A53T ?-synuclein mutant mouse model of Parkinson's disease. PLoS ONE. 2011;6:e17953 pubmed 出版商

Benatti P, Dolfini D, Vigano A, Ravo M, Weisz A, Imbriano C. Specific inhibition of NF-Y subunits triggers different cell proliferation defects. Nucleic Acids Res. 2011;39:5356-68 pubmed 出版商

Gopal U, Bohonowych J, Lema Tome C, Liu A, Garrett Mayer E, Wang B, et al. A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion. PLoS ONE. 2011;6:e17649 pubmed 出版商

Booy E, Henson E, Gibson S. Epidermal growth factor regulates Mcl-1 expression through the MAPK-Elk-1 signalling pathway contributing to cell survival in breast cancer. Oncogene. 2011;30:2367-78 pubmed 出版商

de Oliveira V, Almeida S, Soares H, Crespo A, Marshall Clarke S, Parkhouse R. A novel TLR3 inhibitor encoded by African swine fever virus (ASFV). Arch Virol. 2011;156:597-609 pubmed 出版商

Thai M, Ting P, McLaughlin J, Cheng D, MUSCHEN M, Witte O, et al. ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1. Leukemia. 2011;25:290-300 pubmed 出版商

Byles V, Chmilewski L, Wang J, Zhu L, Forman L, Faller D, et al. Aberrant cytoplasm localization and protein stability of SIRT1 is regulated by PI3K/IGF-1R signaling in human cancer cells. Int J Biol Sci. 2010;6:599-612 pubmed

Wilkie G, Korfali N, Swanson S, Malik P, Srsen V, Batrakou D, et al. Several novel nuclear envelope transmembrane proteins identified in skeletal muscle have cytoskeletal associations. Mol Cell Proteomics. 2011;10:M110.003129 pubmed 出版商

Negishi M, Saraya A, Mochizuki S, Helin K, Koseki H, Iwama A. A novel zinc finger protein Zfp277 mediates transcriptional repression of the Ink4a/arf locus through polycomb repressive complex 1. PLoS ONE. 2010;5:e12373 pubmed 出版商

Ashrafian H, Docherty L, Leo V, Towlson C, Neilan M, Steeples V, et al. A mutation in the mitochondrial fission gene Dnm1l leads to cardiomyopathy. PLoS Genet. 2010;6:e1001000 pubmed 出版商

Androutsellis Theotokis A, Walbridge S, Park D, Lonser R, McKay R. Cholera toxin regulates a signaling pathway critical for the expansion of neural stem cell cultures from the fetal and adult rodent brains. PLoS ONE. 2010;5:e10841 pubmed 出版商

Piens M, Muller M, Bodson M, Baudouin G, Plumier J. A short upstream promoter region mediates transcriptional regulation of the mouse doublecortin gene in differentiating neurons. BMC Neurosci. 2010;11:64 pubmed 出版商

Han S, Yun H, Son D, Tompkins V, Peng L, Chung S, et al. NF-kappaB/STAT3/PI3K signaling crosstalk in iMyc E mu B lymphoma. Mol Cancer. 2010;9:97 pubmed 出版商

Androutsellis Theotokis A, Rueger M, Park D, Boyd J, Padmanabhan R, Campanati L, et al. Angiogenic factors stimulate growth of adult neural stem cells. PLoS ONE. 2010;5:e9414 pubmed 出版商

Heaslip A, Dzierszinski F, Stein B, Hu K. TgMORN1 is a key organizer for the basal complex of Toxoplasma gondii. PLoS Pathog. 2010;6:e1000754 pubmed 出版商

Khaminets A, Hunn J, Könen Waisman S, Zhao Y, Preukschat D, Coers J, et al. Coordinated loading of IRG resistance GTPases on to the Toxoplasma gondii parasitophorous vacuole. Cell Microbiol. 2010;12:939-61 pubmed 出版商

Louie C, Caridi G, Lopes V, Brancati F, Kispert A, Lancaster M, et al. AHI1 is required for photoreceptor outer segment development and is a modifier for retinal degeneration in nephronophthisis. Nat Genet. 2010;42:175-80 pubmed 出版商

Heaslip A, Ems McClung S, Hu K. TgICMAP1 is a novel microtubule binding protein in Toxoplasma gondii. PLoS ONE. 2009;4:e7406 pubmed 出版商

Khelfaoui M, Pavlowsky A, Powell A, Valnegri P, Cheong K, Blandin Y, et al. Inhibition of RhoA pathway rescues the endocytosis defects in Oligophrenin1 mouse model of mental retardation. Hum Mol Genet. 2009;18:2575-83 pubmed 出版商

Bär S, Daeffler L, Rommelaere J, Nüesch J. Vesicular egress of non-enveloped lytic parvoviruses depends on gelsolin functioning. PLoS Pathog. 2008;4:e1000126 pubmed 出版商

Famulski J, Vos L, Sun X, Chan G. Stable hZW10 kinetochore residency, mediated by hZwint-1 interaction, is essential for the mitotic checkpoint. J Cell Biol. 2008;180:507-20 pubmed 出版商

René C, Taulan M, Iral F, Doudement J, L honoré A, Gerbon C, et al. Binding of serum response factor to cystic fibrosis transmembrane conductance regulator CArG-like elements, as a new potential CFTR transcriptional regulation pathway. Nucleic Acids Res. 2005;33:5271-90 pubmed

Nishida K, Yamasaki S, Ito Y, Kabu K, Hattori K, Tezuka T, et al. Fc{epsilon}RI-mediated mast cell degranulation requires calcium-independent microtubule-dependent translocation of granules to the plasma membrane. J Cell Biol. 2005;170:115-26 pubmed

Horne M, Guadagno T. A requirement for MAP kinase in the assembly and maintenance of the mitotic spindle. J Cell Biol. 2003;161:1021-8 pubmed

Hu K, Roos D, Murray J. A novel polymer of tubulin forms the conoid of Toxoplasma gondii. J Cell Biol. 2002;156:1039-50 pubmed

Adams R, Maiato H, Earnshaw W, Carmena M. Essential roles of Drosophila inner centromere protein (INCENP) and aurora B in histone H3 phosphorylation, metaphase chromosome alignment, kinetochore disjunction, and chromosome segregation. J Cell Biol. 2001;153:865-80 pubmed

Hirota T, Morisaki T, Nishiyama Y, Marumoto T, Tada K, Hara T, et al. Zyxin, a regulator of actin filament assembly, targets the mitotic apparatus by interacting with h-warts/LATS1 tumor suppressor. J Cell Biol. 2000;149:1073-86 pubmed