产品简要
公司名称 :
西格玛奥德里奇
其他品牌 :
FLUKA
产品类型 :
抗体
产品名称 :
单克隆抗α微管蛋白在小鼠生产的抗体
目录 :
T9026
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
DM1A
反应物种 :
longfin inshore squid, long-nosed potoroo, red rock crab, medaka, Rhynchospora tenuis, Aspergillus sp., sea lamprey, starlet sea anemone, rye, African green monkey, Hydractinia echinata, Rhynchospora pubera, California sea hare, 人类, 小鼠, 大鼠, , , , , 斑马鱼, 果蝇, common platanna, 秀丽隐杆线虫
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , 免疫组化-石蜡切片, proximity ligation assay
更多信息或购买 :
文章摘录数: 917
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 人类; 图 1h
Zhang J, Wu T, Simon J, Takada M, Saito R, Fan C, et al. VHL substrate transcription factor ZHX2 as an oncogenic driver in clear cell renal cell carcinoma. Science. 2018;361:290-295 pubmed 出版商
  • 免疫组化; 斑马鱼; 1:500; 图 4d
Song P, Perkins B. Developmental expression of the zebrafish Arf-like small GTPase paralogs arl13a and arl13b. Gene Expr Patterns. 2018;29:82-87 pubmed 出版商
  • 免疫印迹; 小鼠
Peltzer N, Darding M, Montinaro A, Dráber P, Draberova H, Kupka S, et al. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature. 2018;557:112-117 pubmed 出版商
  • 免疫印迹; 人类; 图 1d
Muhar M, Ebert A, Neumann T, Umkehrer C, Jude J, Wieshofer C, et al. SLAM-seq defines direct gene-regulatory functions of the BRD4-MYC axis. Science. 2018;360:800-805 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 2c
Ruppert J, Samejima K, Platani M, Molina O, Kimura H, Jeyaprakash A, et al. HP1α targets the chromosomal passenger complex for activation at heterochromatin before mitotic entry. EMBO J. 2018;37: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:100; 图 3a
Qu X, Yuan F, Corona C, Pasini S, Pero M, Gundersen G, et al. Stabilization of dynamic microtubules by mDia1 drives Tau-dependent Aβ1-42 synaptotoxicity. J Cell Biol. 2017;216:3161-3178 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 6a
Magescas J, Sengmanivong L, Viau A, Mayeux A, Dang T, Burtin M, et al. Spindle pole cohesion requires glycosylation-mediated localization of NuMA. Sci Rep. 2017;7:1474 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s2d
Allison R, Edgar J, Pearson G, Rizo T, Newton T, Günther S, et al. Defects in ER-endosome contacts impact lysosome function in hereditary spastic paraplegia. J Cell Biol. 2017;216:1337-1355 pubmed 出版商
  • 免疫细胞化学; 小鼠; 图 s4f
Filipescu D, Naughtin M, Podsypanina K, Lejour V, Wilson L, Gurard Levin Z, et al. Essential role for centromeric factors following p53 loss and oncogenic transformation. Genes Dev. 2017;31:463-480 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 s5c
Bohnacker T, Prota A, Beaufils F, Burke J, Melone A, Inglis A, et al. Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention. Nat Commun. 2017;8:14683 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 s16a
Martínez Martín N, Maldonado P, Gasparrini F, Frederico B, Aggarwal S, Gaya M, et al. A switch from canonical to noncanonical autophagy shapes B cell responses. Science. 2017;355:641-647 pubmed 出版商
  • 免疫细胞化学; 人类; 图 7a
  • 免疫印迹; 人类; 图 3b
Francis J, Newman L, Cunningham L, Kahn R. A Trimer Consisting of the Tubulin-specific Chaperone D (TBCD), Regulatory GTPase ARL2, and ?-Tubulin Is Required for Maintaining the Microtubule Network. J Biol Chem. 2017;292:4336-4349 pubmed 出版商
  • 免疫细胞化学; medaka; 1:100; 图 s10a
Inoue D, Stemmer M, Thumberger T, Ruppert T, Bärenz F, Wittbrodt J, et al. Expression of the novel maternal centrosome assembly factor Wdr8 is required for vertebrate embryonic mitoses. Nat Commun. 2017;8:14090 pubmed 出版商
  • 免疫细胞化学; 果蝇; 1:1000; 图 3a
Qu Y, Hahn I, Webb S, Pearce S, Prokop A. Periodic actin structures in neuronal axons are required to maintain microtubules. Mol Biol Cell. 2017;28:296-308 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 2
Miles D, de Vries N, Gisler S, Lieftink C, Akhtar W, Gogola E, et al. TRIM28 is an Epigenetic Barrier to Induced Pluripotent Stem Cell Reprogramming. Stem Cells. 2017;35:147-157 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s2i
Bendre S, Rondelet A, Hall C, Schmidt N, Lin Y, Brouhard G, et al. GTSE1 tunes microtubule stability for chromosome alignment and segregation by inhibiting the microtubule depolymerase MCAK. J Cell Biol. 2016;215:631-647 pubmed
  • 免疫细胞化学; 人类; 图 2a
Capalbo L, Mela I, Abad M, Jeyaprakash A, Edwardson J, D Avino P. Coordinated regulation of the ESCRT-III component CHMP4C by the chromosomal passenger complex and centralspindlin during cytokinesis. Open Biol. 2016;6: pubmed
  • 免疫印迹; 小鼠; 图 6
  • 免疫印迹; 人类; 图 3
Nowacka J, Baumgartner C, Pelorosso C, Roth M, Zuber J, Baccarini M. MEK1 is required for the development of NRAS-driven leukemia. Oncotarget. 2016;7:80113-80130 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Andriani G, Almeida V, Faggioli F, Mauro M, Tsai W, Santambrogio L, et al. Whole Chromosome Instability induces senescence and promotes SASP. Sci Rep. 2016;6:35218 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 2c
Kanakkanthara A, Jeganathan K, Limzerwala J, Baker D, Hamada M, Nam H, et al. Cyclin A2 is an RNA binding protein that controls Mre11 mRNA translation. Science. 2016;353:1549-1552 pubmed
  • 免疫印迹; 人类; 图 5b
Koch K, Hartmann R, Schröter F, Suwala A, Maciaczyk D, Krüger A, et al. Reciprocal regulation of the cholinic phenotype and epithelial-mesenchymal transition in glioblastoma cells. Oncotarget. 2016;7:73414-73431 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500
Truong D, Puleo J, Llave A, Mouneimne G, Kamm R, Nikkhah M. Breast Cancer Cell Invasion into a Three Dimensional Tumor-Stroma Microenvironment. Sci Rep. 2016;6:34094 pubmed 出版商
  • proximity ligation assay; 小鼠; 1:20; 图 4
Frolikova M, Sebkova N, Ded L, Dvorakova Hortova K. Characterization of CD46 and ?1 integrin dynamics during sperm acrosome reaction. Sci Rep. 2016;6:33714 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1
Kotoku T, Kosaka K, Nishio M, Ishida Y, Kawaichi M, Matsuda E. CIBZ Regulates Mesodermal and Cardiac Differentiation of by Suppressing T and Mesp1 Expression in Mouse Embryonic Stem Cells. Sci Rep. 2016;6:34188 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 s8
Chung I, Reichelt M, Shao L, Akita R, Koeppen H, Rangell L, et al. High cell-surface density of HER2 deforms cell membranes. Nat Commun. 2016;7:12742 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Hong X, Liu W, Song R, Shah J, Feng X, Tsang C, et al. SOX9 is targeted for proteasomal degradation by the E3 ligase FBW7 in response to DNA damage. Nucleic Acids Res. 2016;44:8855-8869 pubmed
  • 免疫印迹; 人类; 1:1000; 图 2c
Padhan N, Nordling T, Sundstrom M, Akerud P, Birgisson H, Nygren P, et al. High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer. BMC Cancer. 2016;16:683 pubmed 出版商
  • 免疫细胞化学; 果蝇; 1:2000; 图 5
  • 免疫印迹; 果蝇; 1:5000; 图 4
Meghini F, Martins T, Tait X, Fujimitsu K, Yamano H, Glover D, et al. Targeting of Fzr/Cdh1 for timely activation of the APC/C at the centrosome during mitotic exit. Nat Commun. 2016;7:12607 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2500; 图 s2
  • 免疫印迹; 人类; 1:2500; 图 4
Perez C, Pérez Zúñiga F, Garrido F, Reytor E, Portillo F, Pajares M. The Oncogene PDRG1 Is an Interaction Target of Methionine Adenosyltransferases. PLoS ONE. 2016;11:e0161672 pubmed 出版商
  • 免疫印迹; 人类; 图 s1
Fokkelman M, BalcıoÄŸlu H, Klip J, Yan K, Verbeek F, Danen E, et al. Cellular adhesome screen identifies critical modulators of focal adhesion dynamics, cellular traction forces and cell migration behaviour. Sci Rep. 2016;6:31707 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 s2
Saatcioglu H, Cuevas I, Castrillon D. Control of Oocyte Reawakening by Kit. PLoS Genet. 2016;12:e1006215 pubmed 出版商
  • 免疫印迹; 小鼠; 图 7
Furukawa Y, Tanemura K, Igarashi K, Ideta Otsuka M, Aisaki K, Kitajima S, et al. Learning and Memory Deficits in Male Adult Mice Treated with a Benzodiazepine Sleep-Inducing Drug during the Juvenile Period. Front Neurosci. 2016;10:339 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1d
Liang J, Cao R, Zhang Y, Xia Y, Zheng Y, Li X, et al. PKM2 dephosphorylation by Cdc25A promotes the Warburg effect and tumorigenesis. Nat Commun. 2016;7:12431 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Dhamad A, Zhou Z, Zhou J, Du Y. Systematic Proteomic Identification of the Heat Shock Proteins (Hsp) that Interact with Estrogen Receptor Alpha (ER?) and Biochemical Characterization of the ER?-Hsp70 Interaction. PLoS ONE. 2016;11:e0160312 pubmed 出版商
  • 免疫印迹; scFv; 图 2c
Tsai S, Chang Y, Swamy K, Chiang R, Huang D. GAGA factor, a positive regulator of global gene expression, modulates transcriptional pausing and organization of upstream nucleosomes. Epigenetics Chromatin. 2016;9:32 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Fritsch K, Mernberger M, Nist A, Stiewe T, Brehm A, Jacob R. Galectin-3 interacts with components of the nuclear ribonucleoprotein complex. BMC Cancer. 2016;16:502 pubmed 出版商
  • 免疫细胞化学; 人类; 1:5000; 图 4
  • 免疫印迹; 人类; 1:5000; 图 2
Meitinger F, Anzola J, Kaulich M, Richardson A, Stender J, Benner C, et al. 53BP1 and USP28 mediate p53 activation and G1 arrest after centrosome loss or extended mitotic duration. J Cell Biol. 2016;214:155-66 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 4
Belvedere R, Bizzarro V, Forte G, Dal Piaz F, Parente L, Petrella A. Annexin A1 contributes to pancreatic cancer cell phenotype, behaviour and metastatic potential independently of Formyl Peptide Receptor pathway. Sci Rep. 2016;6:29660 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4g
Yang D, Yuan Q, Balakrishnan A, Bantel H, Klusmann J, Manns M, et al. MicroRNA-125b-5p mimic inhibits acute liver failure. Nat Commun. 2016;7:11916 pubmed 出版商
  • 免疫印迹; 人类; 图 s3
Bennesch M, Segala G, Wider D, Picard D. LSD1 engages a corepressor complex for the activation of the estrogen receptor ? by estrogen and cAMP. Nucleic Acids Res. 2016;44:8655-8670 pubmed
  • 免疫印迹; African green monkey; 1:5000; 图 1
  • 免疫印迹; 小鼠; 1:5000; 图 3
Mukai K, Konno H, Akiba T, Uemura T, Waguri S, Kobayashi T, et al. Activation of STING requires palmitoylation at the Golgi. Nat Commun. 2016;7:11932 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:400; 图 3c
Eymery A, Liu Z, Ozonov E, Stadler M, Peters A. The methyltransferase Setdb1 is essential for meiosis and mitosis in mouse oocytes and early embryos. Development. 2016;143:2767-79 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1
Yin Y, Gao D, Wang Y, Wang Z, Wang X, Ye J, et al. Tau accumulation induces synaptic impairment and memory deficit by calcineurin-mediated inactivation of nuclear CaMKIV/CREB signaling. Proc Natl Acad Sci U S A. 2016;113:E3773-81 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 3
Matsumura S, Kojidani T, Kamioka Y, Uchida S, Haraguchi T, Kimura A, et al. Interphase adhesion geometry is transmitted to an internal regulator for spindle orientation via caveolin-1. Nat Commun. 2016;7:ncomms11858 pubmed 出版商
  • 免疫组化; 果蝇; 图 3
Bergstralh D, Lovegrove H, Kujawiak I, Dawney N, Zhu J, Cooper S, et al. Pins is not required for spindle orientation in the Drosophila wing disc. Development. 2016;143:2573-81 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 1
Yin Y, Wang Y, Gao D, Ye J, Wang X, Fang L, et al. Accumulation of human full-length tau induces degradation of nicotinic acetylcholine receptor α4 via activating calpain-2. Sci Rep. 2016;6:27283 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000; 图 2
van Ree J, Nam H, Jeganathan K, Kanakkanthara A, van Deursen J. Pten regulates spindle pole movement through Dlg1-mediated recruitment of Eg5 to centrosomes. Nat Cell Biol. 2016;18:814-21 pubmed 出版商
  • 免疫印迹; 人类; 图 5a
Daubon T, Spuul P, Alonso F, Fremaux I, Genot E. VEGF-A stimulates podosome-mediated collagen-IV proteolysis in microvascular endothelial cells. J Cell Sci. 2016;129:2586-98 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 s2
  • 免疫印迹; 人类; 1:5000; 图 6
Brosh R, Hrynyk I, Shen J, Waghray A, Zheng N, Lemischka I. A dual molecular analogue tuner for dissecting protein function in mammalian cells. Nat Commun. 2016;7:11742 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 4
Kobayashi E, Suzuki T, Funayama R, Nagashima T, Hayashi M, Sekine H, et al. Nrf2 suppresses macrophage inflammatory response by blocking proinflammatory cytokine transcription. Nat Commun. 2016;7:11624 pubmed 出版商
  • 免疫印迹; 牛; 1:10,000; 图 2
Umezu K, Hiradate Y, Oikawa T, Ishiguro H, Numabe T, Hara K, et al. Exogenous neurotensin modulates sperm function in Japanese Black cattle. J Reprod Dev. 2016;62:409-14 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 5
Kessler S, Laggai S, Van Wonterg E, Gemperlein K, Muller R, Haybaeck J, et al. Transient Hepatic Overexpression of Insulin-Like Growth Factor 2 Induces Free Cholesterol and Lipid Droplet Formation. Front Physiol. 2016;7:147 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Guinot A, Oeztuerk Winder F, Ventura J. miR-17-92/p38? Dysregulation Enhances Wnt Signaling and Selects Lgr6+ Cancer Stem-like Cells during Lung Adenocarcinoma Progression. Cancer Res. 2016;76:4012-22 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6
de Jong P, Taniguchi K, Harris A, Bertin S, Takahashi N, Duong J, et al. ERK5 signalling rescues intestinal epithelial turnover and tumour cell proliferation upon ERK1/2 abrogation. Nat Commun. 2016;7:11551 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 4
Chang C, Hsu W, Tsai J, Tang C, Tang T. CEP295 interacts with microtubules and is required for centriole elongation. J Cell Sci. 2016;129:2501-13 pubmed 出版商
  • 免疫细胞化学; 人类; 1:500; 图 s1
Rao S, Flores Rodriguez N, Page S, Wong C, Robinson P, Chircop M. The Clathrin-dependent Spindle Proteome. Mol Cell Proteomics. 2016;15:2537-53 pubmed 出版商
  • 免疫印迹; 小鼠; 图 5
Takenaka N, Nihata Y, Satoh T. Rac1 Activation Caused by Membrane Translocation of a Guanine Nucleotide Exchange Factor in Akt2-Mediated Insulin Signaling in Mouse Skeletal Muscle. PLoS ONE. 2016;11:e0155292 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 4
Marei H, Carpy A, Macek B, Malliri A. Proteomic analysis of Rac1 signaling regulation by guanine nucleotide exchange factors. Cell Cycle. 2016;15:1961-74 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 1
Riaz M, Raz Y, van Putten M, Paniagua Soriano G, Krom Y, Florea B, et al. PABPN1-Dependent mRNA Processing Induces Muscle Wasting. PLoS Genet. 2016;12:e1006031 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 6
Marthandan S, Baumgart M, Priebe S, Groth M, Schaer J, Kaether C, et al. Conserved Senescence Associated Genes and Pathways in Primary Human Fibroblasts Detected by RNA-Seq. PLoS ONE. 2016;11:e0154531 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Rapiteanu R, Davis L, Williamson J, Timms R, Paul Luzio J, Lehner P. A Genetic Screen Identifies a Critical Role for the WDR81-WDR91 Complex in the Trafficking and Degradation of Tetherin. Traffic. 2016;17:940-58 pubmed 出版商
  • 免疫印迹; 人类; 图 6
Strappazzon F, Di Rita A, Cianfanelli V, D Orazio M, Nazio F, Fimia G, et al. Prosurvival AMBRA1 turns into a proapoptotic BH3-like protein during mitochondrial apoptosis. Autophagy. 2016;12:963-75 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1
  • 免疫印迹; 人类; 1:1000; 图 6
Lee K, Lee H, Lin H, Tsay H, Tsai F, Shyue S, et al. Role of transient receptor potential ankyrin 1 channels in Alzheimer's disease. J Neuroinflammation. 2016;13:92 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000; 图 1
Mata Garrido J, Casafont I, Tapia O, Berciano M, Lafarga M. Neuronal accumulation of unrepaired DNA in a novel specific chromatin domain: structural, molecular and transcriptional characterization. Acta Neuropathol Commun. 2016;4:41 pubmed 出版商
  • 免疫组化; 果蝇; 1:100; 图 1
Kwenda L, Collins C, Dattoli A, Dunleavy E. Nucleolar activity and CENP-C regulate CENP-A and CAL1 availability for centromere assembly in meiosis. Development. 2016;143:1400-12 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 1
Brüggen B, Kremser C, Bickert A, Ebel P, Vom Dorp K, Schultz K, et al. Defective ceramide synthases in mice cause reduced amplitudes in electroretinograms and altered sphingolipid composition in retina and cornea. Eur J Neurosci. 2016;44:1700-13 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:500; 图 2
Waisbourd Zinman O, Koh H, Tsai S, Lavrut P, Dang C, Zhao X, et al. The toxin biliatresone causes mouse extrahepatic cholangiocyte damage and fibrosis through decreased glutathione and SOX17. Hepatology. 2016;64:880-93 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Chiang T, le Sage C, Larrieu D, Demir M, Jackson S. CRISPR-Cas9(D10A) nickase-based genotypic and phenotypic screening to enhance genome editing. Sci Rep. 2016;6:24356 pubmed 出版商
  • 免疫印迹; 大鼠; 表 3
Taguchi K, Takaku M, Egner P, Morita M, Kaneko T, Mashimo T, et al. Generation of a New Model Rat: Nrf2 Knockout Rats Are Sensitive to Aflatoxin B1 Toxicity. Toxicol Sci. 2016;152:40-52 pubmed 出版商
  • 免疫印迹; 小鼠; 1:5000; 图 1
Juárez Vicente F, Luna Pelaez N, Garcia Dominguez M. The Sumo protease Senp7 is required for proper neuronal differentiation. Biochim Biophys Acta. 2016;1863:1490-8 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Strickland S, Vande Pol S. The Human Papillomavirus 16 E7 Oncoprotein Attenuates AKT Signaling To Promote Internal Ribosome Entry Site-Dependent Translation and Expression of c-MYC. J Virol. 2016;90:5611-5621 pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
McKenzie C, Bassi Z, Debski J, Gottardo M, Callaini G, Dadlez M, et al. Cross-regulation between Aurora B and Citron kinase controls midbody architecture in cytokinesis. Open Biol. 2016;6: pubmed 出版商
  • 免疫细胞化学; 人类; 图 2
Zhao W, Liu J, Zhang X, Deng L. MLL5 maintains spindle bipolarity by preventing aberrant cytosolic aggregation of PLK1. J Cell Biol. 2016;212:829-43 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 3
  • 免疫印迹; 人类; 1:1000; 图 3
Chavali P, Chandrasekaran G, Barr A, Tátrai P, Taylor C, Papachristou E, et al. A CEP215-HSET complex links centrosomes with spindle poles and drives centrosome clustering in cancer. Nat Commun. 2016;7:11005 pubmed 出版商
  • 免疫印迹; 人类; 图 5
Mitxelena J, Apraiz A, Vallejo Rodríguez J, Malumbres M, Zubiaga A. E2F7 regulates transcription and maturation of multiple microRNAs to restrain cell proliferation. Nucleic Acids Res. 2016;: pubmed
  • 免疫细胞化学; 小鼠; 图 2
Makani V, Jang Y, Christopher K, Judy W, Eckstein J, Hensley K, et al. BBB-Permeable, Neuroprotective, and Neurotrophic Polysaccharide, Midi-GAGR. PLoS ONE. 2016;11:e0149715 pubmed 出版商
  • 免疫印迹; 人类; 图 4
Nakayama R, Zhang Y, Czaplinski J, Anatone A, Sicinska E, Fletcher J, et al. Preclinical activity of selinexor, an inhibitor of XPO1, in sarcoma. Oncotarget. 2016;7:16581-92 pubmed 出版商
  • 免疫印迹; 人类; 1:5000; 图 1c
McLaughlin D, Coey C, Yang W, Drohat A, Matunis M. Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo. J Biol Chem. 2016;291:9014-24 pubmed 出版商
  • 免疫印迹; 人类; 1:20,000; 图 3g
Xu Q, Zhang Y, Wei Q, Huang Y, Hu J, Ling K. Phosphatidylinositol phosphate kinase PIPKIγ and phosphatase INPP5E coordinate initiation of ciliogenesis. Nat Commun. 2016;7:10777 pubmed 出版商
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Morris E, Assi K, Salh B, Dedhar S. Integrin-linked kinase links dynactin-1/dynactin-2 with cortical integrin receptors to orient the mitotic spindle relative to the substratum. Sci Rep. 2015;5:8389 pubmed 出版商
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Chan Y, West S. Spatial control of the GEN1 Holliday junction resolvase ensures genome stability. Nat Commun. 2014;5:4844 pubmed 出版商
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Liu J, Zheng L, Ma L, Wang B, Zhao Y, Wu N, et al. Oleanolic acid inhibits proliferation and invasiveness of Kras-transformed cells via autophagy. J Nutr Biochem. 2014;25:1154-1160 pubmed 出版商
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Rotunno M, Auclair J, Maniatis S, Shaffer S, AGAR J, Bosco D. Identification of a misfolded region in superoxide dismutase 1 that is exposed in amyotrophic lateral sclerosis. J Biol Chem. 2014;289:28527-38 pubmed 出版商
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Peng M, Emmadi R, Wang Z, Wiley E, Gann P, Khan S, et al. PTK6/BRK is expressed in the normal mammary gland and activated at the plasma membrane in breast tumors. Oncotarget. 2014;5:6038-48 pubmed
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Ishii H, Saitoh M, Sakamoto K, Kondo T, Katoh R, Tanaka S, et al. Epithelial splicing regulatory proteins 1 (ESRP1) and 2 (ESRP2) suppress cancer cell motility via different mechanisms. J Biol Chem. 2014;289:27386-99 pubmed 出版商
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Passaro C, Volpe M, Botta G, Scamardella E, Perruolo G, Gillespie D, et al. PARP inhibitor olaparib increases the oncolytic activity of dl922-947 in in vitro and in vivo model of anaplastic thyroid carcinoma. Mol Oncol. 2015;9:78-92 pubmed 出版商
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Xu M, Nagati J, Xie J, Li J, Walters H, Moon Y, et al. An acetate switch regulates stress erythropoiesis. Nat Med. 2014;20:1018-26 pubmed 出版商
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James S, Banta T, Barra J, Ciraku L, Coile C, Cuda Z, et al. Restraint of the G2/M transition by the SR/RRM family mRNA shuttling binding protein SNXAHRB1 in Aspergillus nidulans. Genetics. 2014;198:617-33 pubmed 出版商
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Lee Y, Santé J, Comerci C, Cyge B, Menezes L, Li F, et al. Cby1 promotes Ahi1 recruitment to a ring-shaped domain at the centriole-cilium interface and facilitates proper cilium formation and function. Mol Biol Cell. 2014;25:2919-33 pubmed 出版商
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Isogaya K, Koinuma D, Tsutsumi S, Saito R, Miyazawa K, Aburatani H, et al. A Smad3 and TTF-1/NKX2-1 complex regulates Smad4-independent gene expression. Cell Res. 2014;24:994-1008 pubmed 出版商
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Smith C, Matheson T, Trombly D, Sun X, Campeau E, Han X, et al. A separable domain of the p150 subunit of human chromatin assembly factor-1 promotes protein and chromosome associations with nucleoli. Mol Biol Cell. 2014;25:2866-81 pubmed 出版商
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Galletta B, Guillen R, Fagerstrom C, Brownlee C, Lerit D, Megraw T, et al. Drosophila pericentrin requires interaction with calmodulin for its function at centrosomes and neuronal basal bodies but not at sperm basal bodies. Mol Biol Cell. 2014;25:2682-94 pubmed 出版商
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Nickerson K, Homer C, Kessler S, Dixon L, Kabi A, Gordon I, et al. The dietary polysaccharide maltodextrin promotes Salmonella survival and mucosal colonization in mice. PLoS ONE. 2014;9:e101789 pubmed 出版商
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Lodato S, Molyneaux B, Zuccaro E, Goff L, Chen H, Yuan W, et al. Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons. Nat Neurosci. 2014;17:1046-54 pubmed 出版商
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Hopkins J, Hwang G, Jacob J, Sapp N, Bedigian R, Oka K, et al. Meiosis-specific cohesin component, Stag3 is essential for maintaining centromere chromatid cohesion, and required for DNA repair and synapsis between homologous chromosomes. PLoS Genet. 2014;10:e1004413 pubmed 出版商
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Manguan García C, Pintado Berninches L, Carrillo J, Machado Pinilla R, Sastre L, Perez Quilis C, et al. Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells. PLoS ONE. 2014;9:e101424 pubmed 出版商
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Takeda A, Oberoi Khanuja T, Glatz G, Schulenburg K, Scholz R, Carpy A, et al. Ubiquitin-dependent regulation of MEKK2/3-MEK5-ERK5 signaling module by XIAP and cIAP1. EMBO J. 2014;33:1784-801 pubmed 出版商
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O Rourke B, Gomez Ferreria M, Berk R, Hackl A, Nicholas M, O Rourke S, et al. Cep192 controls the balance of centrosome and non-centrosomal microtubules during interphase. PLoS ONE. 2014;9:e101001 pubmed 出版商
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Kim D, Birendra K, Zhu W, Motamedchaboki K, Doye V, Roux K. Probing nuclear pore complex architecture with proximity-dependent biotinylation. Proc Natl Acad Sci U S A. 2014;111:E2453-61 pubmed 出版商
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Soares F, Tattoli I, Rahman M, Robertson S, Belcheva A, Liu D, et al. The mitochondrial protein NLRX1 controls the balance between extrinsic and intrinsic apoptosis. J Biol Chem. 2014;289:19317-30 pubmed 出版商
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Kielar M, Tuy F, Bizzotto S, Lebrand C, de Juan Romero C, Poirier K, et al. Mutations in Eml1 lead to ectopic progenitors and neuronal heterotopia in mouse and human. Nat Neurosci. 2014;17:923-33 pubmed 出版商
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Li R, Tan J, Chen L, Feng J, Liang W, Guo X, et al. Iqcg is essential for sperm flagellum formation in mice. PLoS ONE. 2014;9:e98053 pubmed 出版商
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Cheong F, Feng L, Sarkeshik A, Yates J, Schroer T. Dynactin integrity depends upon direct binding of dynamitin to Arp1. Mol Biol Cell. 2014;25:2171-80 pubmed 出版商
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Kitagawa K, Shibata K, Matsumoto A, Matsumoto M, Ohhata T, Nakayama K, et al. Fbw7 targets GATA3 through cyclin-dependent kinase 2-dependent proteolysis and contributes to regulation of T-cell development. Mol Cell Biol. 2014;34:2732-44 pubmed
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Zavodszky E, Seaman M, Moreau K, Jimenez Sanchez M, Breusegem S, Harbour M, et al. Mutation in VPS35 associated with Parkinson's disease impairs WASH complex association and inhibits autophagy. Nat Commun. 2014;5:3828 pubmed 出版商
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Shaw Hallgren G, Chmielarska Masoumi K, Zarrizi R, Hellman U, Karlsson P, Helou K, et al. Association of nuclear-localized Nemo-like kinase with heat-shock protein 27 inhibits apoptosis in human breast cancer cells. PLoS ONE. 2014;9:e96506 pubmed 出版商
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Thoresen S, Campsteijn C, Vietri M, Schink K, Liestøl K, Andersen J, et al. ANCHR mediates Aurora-B-dependent abscission checkpoint control through retention of VPS4. Nat Cell Biol. 2014;16:550-60 pubmed 出版商
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Garimella S, Gehlhaus K, Dine J, Pitt J, Grandin M, Chakka S, et al. Identification of novel molecular regulators of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis in breast cancer cells by RNAi screening. Breast Cancer Res. 2014;16:R41 pubmed 出版商
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Hayes S, Hng K, Clark P, Thistlethwaite F, Hawkins R, Ang Y. Immunohistochemical assessment of NY-ESO-1 expression in esophageal adenocarcinoma resection specimens. World J Gastroenterol. 2014;20:4011-6 pubmed 出版商
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Touat Hamici Z, Legrain Y, Bulteau A, Chavatte L. Selective up-regulation of human selenoproteins in response to oxidative stress. J Biol Chem. 2014;289:14750-61 pubmed 出版商
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Han X, Cheng D, Song F, Zeng T, An L, Xie K. Decelerated transport and its mechanism of 2,5-hexanedione on middle-molecular-weight neurofilament in rat dorsal root ganglia cells. Neuroscience. 2014;269:192-8 pubmed 出版商
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Feuer S, Liu X, Donjacour A, Lin W, Simbulan R, Giritharan G, et al. Use of a mouse in vitro fertilization model to understand the developmental origins of health and disease hypothesis. Endocrinology. 2014;155:1956-69 pubmed 出版商
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Kuo P, Huang Y, Hsieh C, Lee J, Lin B, Hung L. STK31 is a cell-cycle regulated protein that contributes to the tumorigenicity of epithelial cancer cells. PLoS ONE. 2014;9:e93303 pubmed 出版商
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Rennoll S, Scott S, Yochum G. Targeted repression of AXIN2 and MYC gene expression using designer TALEs. Biochem Biophys Res Commun. 2014;446:1120-5 pubmed 出版商
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Gunkel M, Flottmann B, Heilemann M, Reymann J, Erfle H. Integrated and correlative high-throughput and super-resolution microscopy. Histochem Cell Biol. 2014;141:597-603 pubmed 出版商
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Mackeh R, Lorin S, Ratier A, Mejdoubi Charef N, Baillet A, Bruneel A, et al. Reactive oxygen species, AMP-activated protein kinase, and the transcription cofactor p300 regulate ?-tubulin acetyltransferase-1 (?TAT-1/MEC-17)-dependent microtubule hyperacetylation during cell stress. J Biol Chem. 2014;289:11816-28 pubmed 出版商
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Herve D, Philippi A, Belbouab R, Zerah M, Chabrier S, Collardeau Frachon S, et al. Loss of ?1?1 soluble guanylate cyclase, the major nitric oxide receptor, leads to moyamoya and achalasia. Am J Hum Genet. 2014;94:385-94 pubmed 出版商
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Imamura K, Maeda S, Kawamura I, Matsuyama K, Shinohara N, Yahiro Y, et al. Human immunodeficiency virus type 1 enhancer-binding protein 3 is essential for the expression of asparagine-linked glycosylation 2 in the regulation of osteoblast and chondrocyte differentiation. J Biol Chem. 2014;289:9865-79 pubmed 出版商
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Uno M, Saitoh Y, Mochida K, Tsuruyama E, Kiyono T, Imoto I, et al. NF-?B inducing kinase, a central signaling component of the non-canonical pathway of NF-?B, contributes to ovarian cancer progression. PLoS ONE. 2014;9:e88347 pubmed 出版商
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Ryszawy D, Sarna M, Rak M, Szpak K, Kedracka Krok S, Michalik M, et al. Functional links between Snail-1 and Cx43 account for the recruitment of Cx43-positive cells into the invasive front of prostate cancer. Carcinogenesis. 2014;35:1920-30 pubmed 出版商
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Wong Y, Holzbaur E. The regulation of autophagosome dynamics by huntingtin and HAP1 is disrupted by expression of mutant huntingtin, leading to defective cargo degradation. J Neurosci. 2014;34:1293-305 pubmed 出版商
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Xu C, Fan C, Wang X. Regulation of Mdm2 protein stability and the p53 response by NEDD4-1 E3 ligase. Oncogene. 2015;34:281-9 pubmed 出版商
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Sike A, Nagy E, Vedelek B, Pusztai D, Szerémy P, Venetianer A, et al. mRNA levels of related Abcb genes change opposite to each other upon histone deacetylase inhibition in drug-resistant rat hepatoma cells. PLoS ONE. 2014;9:e84915 pubmed 出版商
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Manil Ségalen M, Culetto E, Legouis R, Lefebvre C. Interactions between endosomal maturation and autophagy: analysis of ESCRT machinery during Caenorhabditis elegans development. Methods Enzymol. 2014;534:93-118 pubmed 出版商
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Klinger M, Wang W, Kuhns S, Bärenz F, Dräger Meurer S, Pereira G, et al. The novel centriolar satellite protein SSX2IP targets Cep290 to the ciliary transition zone. Mol Biol Cell. 2014;25:495-507 pubmed 出版商
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Sharma Walia N, Chandran K, Patel K, Veettil M, Marginean A. The Kaposi's sarcoma-associated herpesvirus (KSHV)-induced 5-lipoxygenase-leukotriene B4 cascade plays key roles in KSHV latency, monocyte recruitment, and lipogenesis. J Virol. 2014;88:2131-56 pubmed 出版商
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Mielcarek M, Landles C, Weiss A, Bradaia A, Seredenina T, Inuabasi L, et al. HDAC4 reduction: a novel therapeutic strategy to target cytoplasmic huntingtin and ameliorate neurodegeneration. PLoS Biol. 2013;11:e1001717 pubmed 出版商
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Rennoll S, Konsavage W, Yochum G. Nuclear AXIN2 represses MYC gene expression. Biochem Biophys Res Commun. 2014;443:217-22 pubmed 出版商
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Tan S, Shui G, Zhou J, Shi Y, Huang J, Xia D, et al. Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway. Autophagy. 2014;10:226-42 pubmed 出版商
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Alves M, Martins A, Vaz C, Correia S, Moreira P, Oliveira P, et al. Metformin and male reproduction: effects on Sertoli cell metabolism. Br J Pharmacol. 2014;171:1033-42 pubmed 出版商
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Cochrane A. HIV-1 Rev function and RNA nuclear-cytoplasmic export. Methods Mol Biol. 2014;1087:103-14 pubmed 出版商
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Garcia E, Santana Martínez R, Silva Islas C, Colín González A, Galvan Arzate S, Heras Y, et al. S-allyl cysteine protects against MPTP-induced striatal and nigral oxidative neurotoxicity in mice: participation of Nrf2. Free Radic Res. 2014;48:159-67 pubmed 出版商
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Aukkarasongsup P, Haruyama N, Matsumoto T, Shiga M, Moriyama K. Periostin inhibits hypoxia-induced apoptosis in human periodontal ligament cells via TGF-? signaling. Biochem Biophys Res Commun. 2013;441:126-32 pubmed 出版商
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Hashizume C, Kobayashi A, Wong R. Down-modulation of nucleoporin RanBP2/Nup358 impaired chromosomal alignment and induced mitotic catastrophe. Cell Death Dis. 2013;4:e854 pubmed 出版商
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Hashizume C, Moyori A, Kobayashi A, Yamakoshi N, Endo A, Wong R. Nucleoporin Nup62 maintains centrosome homeostasis. Cell Cycle. 2013;12:3804-16 pubmed 出版商
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Martinez Sanchez A, Murphy C. miR-1247 functions by targeting cartilage transcription factor SOX9. J Biol Chem. 2013;288:30802-14 pubmed 出版商
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Kim Y, Zheng Y. Generation and characterization of a conditional deletion allele for Lmna in mice. Biochem Biophys Res Commun. 2013;440:8-13 pubmed 出版商
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Chen Y, Kamili A, Hardy J, Groblewski G, Khanna K, Byrne J. Tumor protein D52 represents a negative regulator of ATM protein levels. Cell Cycle. 2013;12:3083-97 pubmed 出版商
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Horton J, Stefanick D, Gassman N, Williams J, Gabel S, Cuneo M, et al. Preventing oxidation of cellular XRCC1 affects PARP-mediated DNA damage responses. DNA Repair (Amst). 2013;12:774-85 pubmed 出版商
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Yuki K, Yoshida T, Miyake S, Tsubota K, Ozawa Y. Neuroprotective role of superoxide dismutase 1 in retinal ganglion cells and inner nuclear layer cells against N-methyl-d-aspartate-induced cytotoxicity. Exp Eye Res. 2013;115:230-8 pubmed 出版商
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Alfonso Pérez T, Domínguez Sánchez M, Garcia Dominguez M, Reyes J. Cytoplasmic interaction of the tumour suppressor protein hSNF5 with dynamin-2 controls endocytosis. Oncogene. 2014;33:3064-74 pubmed 出版商
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Walser R, Burke J, Gogvadze E, Bohnacker T, Zhang X, Hess D, et al. PKC? phosphorylates PI3K? to activate it and release it from GPCR control. PLoS Biol. 2013;11:e1001587 pubmed 出版商
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Zhang L, Wahlin K, Li Y, Masuda T, Yang Z, Zack D, et al. RIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factors. Mol Vis. 2013;19:1371-86 pubmed
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Maddaluno L, Rudini N, Cuttano R, Bravi L, Giampietro C, Corada M, et al. EndMT contributes to the onset and progression of cerebral cavernous malformations. Nature. 2013;498:492-6 pubmed 出版商
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Samwer M, Dehne H, Spira F, Kollmar M, Gerlich D, Urlaub H, et al. The nuclear F-actin interactome of Xenopus oocytes reveals an actin-bundling kinesin that is essential for meiotic cytokinesis. EMBO J. 2013;32:1886-902 pubmed 出版商
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Brochier C, Dennis G, Rivieccio M, McLaughlin K, Coppola G, Ratan R, et al. Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons. J Neurosci. 2013;33:8621-32 pubmed 出版商
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Grabole N, Tischler J, Hackett J, Kim S, Tang F, Leitch H, et al. Prdm14 promotes germline fate and naive pluripotency by repressing FGF signalling and DNA methylation. EMBO Rep. 2013;14:629-37 pubmed 出版商
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Moreno A, Soleto I, García Sanz P, Moreno Bueno G, Palmero I. ING4 regulates a secretory phenotype in primary fibroblasts with dual effects on cell proliferation and tumor growth. Oncogene. 2014;33:1945-53 pubmed 出版商
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Reginensi A, Scott R, Gregorieff A, Bagherie Lachidan M, Chung C, Lim D, et al. Yap- and Cdc42-dependent nephrogenesis and morphogenesis during mouse kidney development. PLoS Genet. 2013;9:e1003380 pubmed 出版商
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Luo M, Ling T, Xie W, Sun H, Zhou Y, Zhu Q, et al. NuRD blocks reprogramming of mouse somatic cells into pluripotent stem cells. Stem Cells. 2013;31:1278-86 pubmed 出版商
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Dush M, Nascone Yoder N. Jun N-terminal kinase maintains tissue integrity during cell rearrangement in the gut. Development. 2013;140:1457-66 pubmed 出版商
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Trakala M, Fernández Miranda G, Perez de Castro I, Heeschen C, Malumbres M. Aurora B prevents delayed DNA replication and premature mitotic exit by repressing p21(Cip1). Cell Cycle. 2013;12:1030-41 pubmed 出版商
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Peng X, Gao H, Wang Y, Yang B, Liu T, Sun Y, et al. Conversion of rat embryonic stem cells into neural precursors in chemical-defined medium. Biochem Biophys Res Commun. 2013;431:783-7 pubmed 出版商
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Gu B, Eick D, Bensaude O. CTD serine-2 plays a critical role in splicing and termination factor recruitment to RNA polymerase II in vivo. Nucleic Acids Res. 2013;41:1591-603 pubmed 出版商
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Tattoli I, Philpott D, Girardin S. The bacterial and cellular determinants controlling the recruitment of mTOR to the Salmonella-containing vacuole. Biol Open. 2012;1:1215-25 pubmed 出版商
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Newman A, Scholefield C, Kemp A, Newman M, McIver E, Kamal A, et al. TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1bp1/Ndp52 and non-canonical NF-?B signalling. PLoS ONE. 2012;7:e50672 pubmed 出版商
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Fan C, Lum M, Xu C, Black J, Wang X. Ubiquitin-dependent regulation of phospho-AKT dynamics by the ubiquitin E3 ligase, NEDD4-1, in the insulin-like growth factor-1 response. J Biol Chem. 2013;288:1674-84 pubmed 出版商
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Jullien L, Mestre M, Roux P, Gire V. Eroded human telomeres are more prone to remain uncapped and to trigger a G2 checkpoint response. Nucleic Acids Res. 2013;41:900-11 pubmed 出版商
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Gao M, Rendtlew Danielsen J, Wei L, Zhou D, Xu Q, Li M, et al. A novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrity. PLoS ONE. 2012;7:e49687 pubmed 出版商
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Ribeiro Varandas E, Viegas W, Sofia Pereira H, Delgado M. Bisphenol A at concentrations found in human serum induces aneugenic effects in endothelial cells. Mutat Res. 2013;751:27-33 pubmed 出版商
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Aivar P, Fernandez Orth J, Gomis Pèrez C, Alberdi A, Alaimo A, Rodriguez M, et al. Surface expression and subunit specific control of steady protein levels by the Kv7.2 helix A-B linker. PLoS ONE. 2012;7:e47263 pubmed 出版商
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Dinh P, Beura L, Das P, Panda D, Das A, Pattnaik A. Induction of stress granule-like structures in vesicular stomatitis virus-infected cells. J Virol. 2013;87:372-83 pubmed 出版商
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Coffey K, Blackburn T, Cook S, Golding B, Griffin R, Hardcastle I, et al. Characterisation of a Tip60 specific inhibitor, NU9056, in prostate cancer. PLoS ONE. 2012;7:e45539 pubmed 出版商
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Pakala S, Nair V, Reddy S, Kumar R. Signaling-dependent phosphorylation of mitotic centromere-associated kinesin regulates microtubule depolymerization and its centrosomal localization. J Biol Chem. 2012;287:40560-9 pubmed 出版商
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Hebras C, McDougall A. Urochordate ascidians possess a single isoform of Aurora kinase that localizes to the midbody via TPX2 in eggs and cleavage stage embryos. PLoS ONE. 2012;7:e45431 pubmed 出版商
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Wallmen B, Schrempp M, Hecht A. Intrinsic properties of Tcf1 and Tcf4 splice variants determine cell-type-specific Wnt/?-catenin target gene expression. Nucleic Acids Res. 2012;40:9455-69 pubmed 出版商
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Ma M, Chircop M. SNX9, SNX18 and SNX33 are required for progression through and completion of mitosis. J Cell Sci. 2012;125:4372-82 pubmed 出版商
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产品信息
目录号 :
T9026
品牌 :
SIGMA
名称 :
单克隆抗α微管蛋白在小鼠生产的抗体
产品类型 :
化学品
名字后缀 :
clone DM1A, ascites fluid
储存 :
-20C
储存温度 :
-20C
运输的 :
干冰
同义词 :
单克隆抗α微管蛋白
unspsc code :
12352203
wgk :
3
抗体形态 :
ascites fluid
应用(s) :
indirect immunofluorescence: 1:500 using cultured chicken fibroblasts
物种活性 :
酵母, 人类, 鸡, 大鼠, 两栖动物, 真菌, 牛, 小鼠
免疫原 :
微管来自鸡胚胎大脑
克隆 :
DM1A
分子量 :
antigen mol wt ~50 kDa
更多信息或购买 :
公司信息
西格玛奥德里奇
上海市徐汇区淮海中路1010号嘉华中心41楼
techservCN@sial.com
http://www.sigmaaldrich.com/china-mainland.html
800-819-3336 400-620-3333 86-21-6141 5566
公司总部: 美国
Sigma-Aldrich是一家在生命科学领域领先的且拥有高科技产品的公司,致力于为生命科学、制药化工等领域提供高质量的服务和产品。