产品简要
信息索取 :
公司名称 :
SignalChem Pharmaceuticals
产品类型 :
蛋白
产品名称 :
BRAF, 活性的
目录 :
B08-11G
规格 :
5微克/10微克
价格 :
205/295美元
更多信息或购买 :
图像
图像 1 :
SignalChem Pharmaceuticals B08-11G 图像 1
Sample Kinase Activity Plot. For specific information on a given lot, see related technical data sheet.
图像 2 :
SignalChem Pharmaceuticals B08-11G 图像 2
Sample Purity Data. For specific information on a given lot, see related technical data sheet.
产品信息
目录代码 :
B08-11G
产品名称 :
BRAF, 活性的
产品类型 :
活性的激酶
宿主物种 :
Sf9昆虫细胞美国杆状病毒
共轭 :
谷胱甘肽S-转移酶
规格 :
5微克/10微克
标价 :
205/295美元
基因编号 :
NM_004333
产品描述 :
Recombinant human BRAF (416-766) was expressed by baculovirus in Sf9 insect cells using a N-terminal GST tag.
物种摘要 :
人类
背景 :
BRAF is a member of the RAF family that is activated by members of the Ras family upon growth factor-induced stimulation. Active Ras can induce heterodimerization of cRaf and BRAF and this may explain the observed cooperativity of cRaf and BRaf in cells responding to growth factor signals (1). Activating mutations in the BRAF gene are present in a large percentage of human malignant melanomas and in a proportion of colon cancers. The vast majority of these mutations result in a valine to glutamic acid change at residue 599 within the activation segment of B-RAF (2).
别名 :
BRAF1, RAFB1, B-raf 1, MGC126806, MGC138284
纯度 :
>75%
缓冲液 :
50mM三羟甲基氨基甲烷氯化氢, pH值7.5, 150mM氯化钠, 0.25mM DTT, 0.1mM乙二醇-双-(2-氨基乙醚)四乙酸, 0.1mM乙二胺四乙酸, 0.1mM苯甲基磺酰氟, 25% 甘油
包装 :
干冰
浓度 :
0.1微克/微升
用途 :
Kinase Assay, Western Blot
应用摘要 :
The specific activity was determined to be 74 nmol/min/mg as per activity assay protocol.
储存 :
Store product at –70ºC. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
更多信息或购买 :
公司信息
SignalChem Pharmaceuticals
#110-13120 Vanier Place
Richmond, BC, Canada, V6V 2J2
info@signalchem.com
www.signalchem.com
1-604-232-3200
公司总部: 加拿大