抗体

抗Janus激酶2

J02-63R

100微克

315美元

多克隆

兔

nonconjugated

人类, 小鼠

抗Janus激酶2

Isoform Specific Antibody

兔

多克隆

100微克

315美元

NM_004972

兔多克隆抗体

Western blot JAK2 from human and mouse cells JAK2 from other species may also be detectable.

人类和小鼠

JAK2 is a member of intracellular non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway (1). JAK2 has two near-identical phosphate-transferring domains. One domain exhibits the kinase activity while the other stabilizes the JAK conformational structure. JAK2 is the predominant JAK kinase activated in response to several growth factors and cytokines such as IL-3, GM-CSF and erythropoietin. JAK2 has been found to be constitutively associated with the prolactin receptor and is required for responses to gamma interferon (2).

合成多肽对应于氨基酸1005-1009人的Janus激酶2

Janus激酶2蛋白

识别Janus激酶2蛋白

亲和色谱

PBS pH值7.4, 0.02% 叠氮化钠, 50% 甘油

Gel packs

1.0微克/微升

免疫印迹

Ideal working dilutions for each application should be empirically determined by the investigator.

Store at 4°C (add 0.1% NaN3) for several months, and at -20°C for longer periods. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For optimal performance, avoid repeated handling and multiple freeze/thaw cycles.