产品简要
公司名称 :
北京义翘神州
产品类型 :
蛋白
产品名称 :
Human ACE2 / Angiotensin-Converting Enzyme 2 Protein (His Tag) (HPLC-verified)
目录 :
10108-H08H
规格 :
100微克
价格 :
558美元
更多信息或购买 :
文章摘录数: 17
参考文献
Ehling R, Weber C, Mason D, Friedensohn S, Wagner B, Bieberich F, et al. SARS-CoV-2 reactive and neutralizing antibodies discovered by single-cell sequencing of plasma cells and mammalian display. Cell Rep. 2022;38:110242 pubmed 出版商
Gunnels T, Stranford D, Mitrut R, Kamat N, Leonard J. Elucidating design principles for engineering cell-derived vesicles to inhibit SARS-CoV-2 infection. bioRxiv. 2021;: pubmed 出版商
Kim S, Liu Y, Lei Z, Dicker J, Cao Y, Zhang X, et al. Differential Interactions between Human ACE2 and Spike RBD of SARS-CoV-2 Variants of Concern. J Chem Theory Comput. 2021;17:7972-7979 pubmed 出版商
Song J, Chow R, Pena Hernandez M, Zhang L, Loeb S, So E, et al. LRRC15 is an inhibitory receptor blocking SARS-CoV-2 spike-mediated entry in trans. bioRxiv. 2021;: pubmed 出版商
Chang X, Zeltins A, Mohsen M, Gharailoo Z, Zha L, Liu X, et al. A Novel Double Mosaic Virus-like Particle-Based Vaccine against SARS-CoV-2 Incorporates Both Receptor Binding Motif (RBM) and Fusion Domain. Vaccines (Basel). 2021;9: pubmed 出版商
Hojjat Jodaylami M, Djaïleb A, Ricard P, Lavallée É, Cellier Goetghebeur S, Parker M, et al. Cross-reactivity of antibodies from non-hospitalized COVID-19 positive individuals against the native, B.1.351, B.1.617.2, and P.1 SARS-CoV-2 spike proteins. Sci Rep. 2021;11:21601 pubmed 出版商
Pan X, Shi J, Hu X, Wu Y, Zeng L, Yao Y, et al. RBD-homodimer, a COVID-19 subunit vaccine candidate, elicits immunogenicity and protection in rodents and nonhuman primates. Cell Discov. 2021;7:82 pubmed 出版商
Passariello M, Vetrei C, Amato F, De Lorenzo C. Interactions of Spike-RBD of SARS-CoV-2 and Platelet Factor 4: New Insights in the Etiopathogenesis of Thrombosis. Int J Mol Sci. 2021;22: pubmed 出版商
Ouyang W, Xie T, Fang H, Gao C, Stantchev T, Clouse K, et al. Variable Induction of Pro-Inflammatory Cytokines by Commercial SARS CoV-2 Spike Protein Reagents: Potential Impacts of LPS on In Vitro Modeling and Pathogenic Mechanisms In Vivo. Int J Mol Sci. 2021;22: pubmed 出版商
Guo Y, Huang L, Zhang G, Yao Y, Zhou H, Shen S, et al. A SARS-CoV-2 neutralizing antibody with extensive Spike binding coverage and modified for optimal therapeutic outcomes. Nat Commun. 2021;12:2623 pubmed 出版商
Liu Y, Liu J, Plante K, Plante J, Xie X, Zhang X, et al. The N501Y spike substitution enhances SARS-CoV-2 transmission. bioRxiv. 2021;: pubmed 出版商
Zhu Z, Qiu X, Wu S, Liu Y, Zhao T, Sun Z, et al. Blocking Effect of Demethylzeylasteral on the Interaction between Human ACE2 Protein and SARS-CoV-2 RBD Protein Discovered Using SPR Technology. Molecules. 2020;26: pubmed 出版商
Hanson Q, Wilson K, Shen M, Itkin Z, Eastman R, Shinn P, et al. Targeting ACE2-RBD Interaction as a Platform for COVID-19 Therapeutics: Development and Drug-Repurposing Screen of an AlphaLISA Proximity Assay. ACS Pharmacol Transl Sci. 2020;3:1352-1360 pubmed 出版商
Daly J, Simonetti B, Klein K, Chen K, Williamson M, Antón Plágaro C, et al. Neuropilin-1 is a host factor for SARS-CoV-2 infection. Science. 2020;370:861-865 pubmed 出版商
Chi X, Liu X, Wang C, Zhang X, Li X, Hou J, et al. Humanized single domain antibodies neutralize SARS-CoV-2 by targeting the spike receptor binding domain. Nat Commun. 2020;11:4528 pubmed 出版商
Lv Z, Deng Y, Ye Q, Cao L, Sun C, Fan C, et al. Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody. Science. 2020;369:1505-1509 pubmed 出版商
Hanson Q, Wilson K, Shen M, Itkin Z, Eastman R, Shinn P, et al. Targeting ACE2-RBD interaction as a platform for COVID19 therapeutics: Development and drug repurposing screen of an AlphaLISA proximity assay. bioRxiv. 2020;: pubmed 出版商
图像
图像 1 :
北京义翘神州 10108-H08H 图像 1
产品信息
提示 :
Online
目录代码 :
10108-H08H
产品名称 :
Human ACE2 / Angiotensin-Converting Enzyme 2 Protein (His Tag) (HPLC-verified)
产品类型 :
蛋白
宿主物种 :
HEK293细胞
共轭 :
C多聚组氨酸
规格 :
100微克
标价 :
558美元
基因编号 :
NP_068576.1
产品描述 :
A DNA sequence encoding the human ACE2 (NP_068576.1) (Met1-Ser740) was expressed with a polyhistidine tag at the C-terminus.
物种摘要 :
人类
别名 :
ACE2
特异性 :
1. Measured by its binding ability in a functional ELISA. Immobilized 2019-nCoV Spike Protein (RBD, mFc Tag)(Cat: 40592-V05H) at 2 μg/mL (100 μL/well) can bind human ACE2 protein (His tag), the EC50 of ACE2 is 10-30 ng/mL. 2. Measured by its ability to cleave a fluorogenic peptide substrate, McaYVADAPK (Dnp)OH, R&D Systems, Catalog # ES007. The specific activity is >1000 pmols/min/μg.
纯度 :
> 95 % as determined by SDS-PAGE. > 90 % as determined by SEC-HPLC.
缓冲液 :
Lyophilized from sterile PBS, pH 7.4.
包装 :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
储存 :
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
更多信息或购买 :
公司信息
北京义翘神州
北京市北京经济技术开发区科创十街18号院9号楼
Order@Sinobiological.com
http://www.sinobiological.cn
400-890-9989
公司总部: 中国
北京义翘神州科技股份有限公司(Sino Biological Inc.)是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司,主要业务有重组蛋白、抗体、基因和培养基等产品,以及重组蛋白、抗体的开发和生物分析检测等服务。

义翘科技为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。义翘科技目前生产和销售的现货产品种类超过4.6万种,能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求,并覆盖生命科学研究的多个领域,为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供“一站式”生物试剂产品和技术服务。

义翘科技的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司,累计客户数量超过5,000个,品牌声誉不断累积,已成为生物试剂行业国内领先的科技公司之一。