产品简要
公司名称 :
北京义翘神州
产品类型 :
蛋白
产品名称 :
人类肿瘤坏死因子甲/TNFA蛋白
目录 :
10602-HNAE
规格 :
100微克
价格 :
198美元
更多信息或购买 :
文章摘录数: 21
出版应用/物种/样本/稀释参考文献
  • 酶联免疫吸附测定; 人类
Du J, Rehm B. Purification of target proteins from intracellular inclusions mediated by intein cleavable polyhydroxyalkanoate synthase fusions. Microb Cell Fact. 2017;16:184 pubmed 出版商
  • 流式细胞仪; 人类
Shen Y, Li G, Gu C, Chen B, Chen A, Li H, et al. T0001, a variant of TNFR2-Fc fusion protein, exhibits improved Fc effector functions through increased binding to membrane-bound TNFα. PLoS ONE. 2017;12:e0177891 pubmed 出版商
Zhang J, Zhou B, Sun R, Ai Y, Cheng K, Li F, et al. The metabolite α-KG induces GSDMC-dependent pyroptosis through death receptor 6-activated caspase-8. Cell Res. 2021;: pubmed 出版商
Gan D, Cheng W, Ke L, Sun A, Jia Q, Chen J, et al. Repurposing of Pirfenidone (Anti-Pulmonary Fibrosis Drug) for Treatment of Rheumatoid Arthritis. Front Pharmacol. 2021;12:631891 pubmed 出版商
Hou P, Luo L, Chen H, Chen Q, Bian X, Wu S, et al. Ectosomal PKM2 Promotes HCC by Inducing Macrophage Differentiation and Remodeling the Tumor Microenvironment. Mol Cell. 2020;78:1192-1206.e10 pubmed 出版商
Wu Y, Li C, Xia S, Tian X, Kong Y, Wang Z, et al. Identification of Human Single-Domain Antibodies against SARS-CoV-2. Cell Host Microbe. 2020;27:891-898.e5 pubmed 出版商
Christler A, Felföldi E, Mosor M, Sauer D, Walch N, Dürauer A, et al. Semi-automation of process analytics reduces operator effect. Bioprocess Biosyst Eng. 2020;43:753-764 pubmed 出版商
Hu Y, Liu J, Li X, Cai Y, He C, Li N, et al. Downregulation of tumor suppressor RACK1 by Helicobacter pylori infection promotes gastric carcinogenesis through the integrin β-1/NF-κB signaling pathway. Cancer Lett. 2019;450:144-154 pubmed 出版商
Zhou B, Zhang J, Liu X, Chen H, Ai Y, Cheng K, et al. Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis. Cell Res. 2018;28:1171-1185 pubmed 出版商
Sun J, Cui H, Gao Y, Pan Y, Zhou K, Huang J, et al. TGF-α Overexpression in Breast Cancer Bone Metastasis and Primary Lesions and TGF-α Enhancement of Expression of Procancer Metastasis Cytokines in Bone Marrow Mesenchymal Stem Cells. Biomed Res Int. 2018;2018:6565393 pubmed 出版商
Zhang C, Jiang H, Wang P, Liu H, Sun X. Transcription factor NF-kappa B represses ANT1 transcription and leads to mitochondrial dysfunctions. Sci Rep. 2017;7:44708 pubmed 出版商
Lei H, Li X, Jing B, Xu H, Wu Y. Human S100A7 Induces Mature Interleukin1? Expression by RAGE-p38 MAPK-Calpain1 Pathway in Psoriasis. PLoS ONE. 2017;12:e0169788 pubmed 出版商
Lin X, Chen Q, Huang C, Xu X. CYLD Promotes TNF-?-Induced Cell Necrosis Mediated by RIP-1 in Human Lung Cancer Cells. Mediators Inflamm. 2016;2016:1542786 pubmed
Button R, Vincent J, Strang C, Luo S. Dual PI-3 kinase/mTOR inhibition impairs autophagy flux and induces cell death independent of apoptosis and necroptosis. Oncotarget. 2016;7:5157-75 pubmed 出版商
Xu Y, Cheng Q, Yang B, Yu S, Xu F, Lu L, et al. Increased sCD200 Levels in Vitreous of Patients With Proliferative Diabetic Retinopathy and Its Correlation With VEGF and Proinflammatory Cytokines. Invest Ophthalmol Vis Sci. 2015;56:6565-72 pubmed 出版商
Cao W, Li H, Zhang J, Li D, Acheampong D, Chen Z, et al. Periplasmic expression optimization of VEGFR2 D3 adopting response surface methodology: antiangiogenic activity study. Protein Expr Purif. 2013;90:55-66 pubmed 出版商
Chen X, Wang C, Xu L, Chen X, Wang W, Yang G, et al. A laboratory evaluation of medicinal herbs used in china for the treatment of hand, foot, and mouth disease. Evid Based Complement Alternat Med. 2013;2013:504563 pubmed 出版商
Chen X, Qiao H, Liu T, Yang Z, Xu L, Xu Y, et al. Inhibition of herpes simplex virus infection by oligomeric stilbenoids through ROS generation. Antiviral Res. 2012;95:30-6 pubmed 出版商
Feng R, Guo Z, Yan C, Li E, Tan R, Ge H. Anti-inflammatory flavonoids from Cryptocarya chingii. Phytochemistry. 2012;76:98-105 pubmed 出版商
Jia D, Yang H, Wan L, Cheng J, Lu X. Production of bioactive, SUMO-modified, and native-like TNF-? of the rhesus monkey, Macaca mulatta, in Escherichia coli. Appl Microbiol Biotechnol. 2012;93:2345-55 pubmed 出版商
Chen X, Wang Z, Yang Z, Wang J, Xu Y, Tan R, et al. Houttuynia cordata blocks HSV infection through inhibition of NF-?B activation. Antiviral Res. 2011;92:341-5 pubmed 出版商
图像
图像 1 :
北京义翘神州 10602-HNAE 图像 1
产品信息
提示 :
Online
目录代码 :
10602-HNAE
产品名称 :
人类肿瘤坏死因子甲/TNFA蛋白
产品类型 :
蛋白
宿主物种 :
大肠杆菌
共轭 :
天然
规格 :
100微克
标价 :
198美元
基因编号 :
NP_000585.2
产品描述 :
A DNA sequence encoding the human TNF-α soluble form (NP_000585.2) (Val 77-Leu 233) was expressed, with an initial Met at the N-terminus.
物种摘要 :
人类
别名 :
肿瘤坏死因子
特异性 :
1. Measured in a cytotoxicity assay using L929 mouse fibrosarcoma cells in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is typically 5-50 pg/mL. 2. Labeled biotin to TNF-alpha Protein, Human, Recombinant by a certain molar ratio; Using the Octet RED System, the affinity constant (Kd) of TNF-alpha Protein, Human, Recombinant, Biotinylated(Cat. 10602-HNAE-B) bound to Humira was 0.1 nM.
纯度 :
> 95 % as determined by SDS-PAGE
缓冲液 :
Lyophilized from sterile PBS, pH 7.4
包装 :
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise.
储存 :
Store it under sterile conditions at -20℃ to -80℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
更多信息或购买 :
公司信息
北京义翘神州
北京市北京经济技术开发区科创十街18号院9号楼
Order@Sinobiological.com
http://www.sinobiological.cn
400-890-9989
公司总部: 中国
北京义翘神州科技股份有限公司(Sino Biological Inc.)是一家从事生物试剂研发、生产、销售并提供技术服务的生物科技公司,主要业务有重组蛋白、抗体、基因和培养基等产品,以及重组蛋白、抗体的开发和生物分析检测等服务。

义翘科技为全球的药品研发企业和生命科学研究机构提供高质量的生物试剂产品和高水平的技术服务。义翘科技目前生产和销售的现货产品种类超过4.6万种,能够全面满足客户对于最接近人体天然蛋白结构和性质的重组蛋白需求,并覆盖生命科学研究的多个领域,为分子生物学、细胞生物学、免疫学、发育生物学、干细胞研究等基础科研方向和创新药物研发提供“一站式”生物试剂产品和技术服务。

义翘科技的客户涵盖大学、科研院所、医药研发企业等国内外各类生物研发单位。目前公司已经在美国、欧洲建立了子公司,累计客户数量超过5,000个,品牌声誉不断累积,已成为生物试剂行业国内领先的科技公司之一。