抗体

Anti-Phospho-Cofilin (S3) antibody

STJ90230

100μl

150美元

多克隆

兔

nonconjugated

磷酸化

免疫印迹, 酶联免疫吸附测定, 免疫组化-石蜡切片

Anti-Phospho-Cofilin (S3) antibody

一抗

兔

多克隆

未共轭

磷酸化

IgG

100μl

150美元

Cofilin is a protein encoded by the JAK1 gene which is approximately 133,2 kDa. Cofilin is localised to the endomembrane system and is involved in RET signalling, common cytokine receptor gamma-chain family signalling pathways, Th17 cell differentiation and IL27-mediated signalling events. It phosphorylates STAT proteins and plays a key role in interferon-alpha/beta and interferon-gamma signal transduction. Cofilin is expressed at higher levels in primary colon tumor than normal colon tissue. Mutations in the JAK1 gene may result in mixed lacrimal gland cancer, t-cell prolymphocytic leukemia and chilblain lupus. The antibody STJ90230 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous Cofilin protein which only binds about S3 when S3 is phosphorylated.

人类, 小鼠, 大鼠

CFL1 antibody, CFL antibody, Cofilin-1 antibody, 18 kDa phosphoprotein antibody, p18 antibody, Cofilin, non-muscle isoform antibody, Phospho-Cofilin (S3) antibody

Synthesized peptide derived from human Cofilin around the phosphorylation site of S3.

10-90氨基酸

Endomembrane system; Peripheral membrane protein. Note=Wholly intracellular, possibly membrane associated.

Phospho-Cofilin (S3) Polyclonal Antibody detects endogenous levels of Cofilin protein only when phosphorylated at S3.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

液体PBS含50% 甘油, 0.5% BSA

0.02% 叠氮化钠

1毫克/毫升

免疫印迹, 免疫组化-p, 酶联免疫吸附测定

Store at -20°C, and avoid repeat freeze-thaw cycles.