抗体

抗磷酸化E2F(T433)抗体

STJ90458

100μl

150美元

多克隆

兔

nonconjugated

磷酸化

免疫印迹, 酶联免疫吸附测定

抗磷酸化E2F(T433)抗体

一抗

兔

多克隆

未共轭

磷酸化

IgG

100μl

150美元

E2F-1 is a protein encoded by the E2F1 gene which is approximately 46,9 kDa. E2F-1 is localised to the nucleus. It is involved in CDK-mediated phosphorylation and removal of Cdc6, glioma, E2F mediated regulation of DNA replication and activation of BH3-only proteins. It is a transcription activator that binds DNA cooperatively with DP proteins through the E2 recognition site found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication. E2F-1 is expressed in the skin, pancreas and nervous system. Mutations in the E2F1 gene may result in retinoblastoma and pharyngoconjunctival fever. STJ90458 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This primary antibody specifically binds to endogenous E2F-1 protein which only binds about T433 when T433 is phosphorylated.

人类, 小鼠

E2F1 antibody, RBBP3 antibody, Transcription factor E2F1 antibody, E2F-1 antibody, PBR3 antibody, Retinoblastoma-associated protein 1 antibody, RBAP-1 antibody, Retinoblastoma-binding protein 3 antibody, RBBP-3 antibody, pRB-binding protein E2F-1 antibody, Phospho-E2F-1 (T433) antibody

Synthesized peptide derived from human E2F-1 around the phosphorylation site of T433.

370-450氨基酸

Nucleus.

Phospho-E2F-1 (T433) Polyclonal Antibody detects endogenous levels of E2F-1 protein only when phosphorylated at T433.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

液体PBS含50% 甘油, 0.5% BSA

0.02% 叠氮化钠

1毫克/毫升

免疫印迹, 酶联免疫吸附测定

Store at -20°C, and avoid repeat freeze-thaw cycles.