抗体

Anti-Cbl antibody

STJ92057

100μl

150美元

多克隆

兔

nonconjugated

免疫印迹, 酶联免疫吸附测定, 免疫组化-石蜡切片

Anti-Cbl antibody

一抗

兔

多克隆

未共轭

IgG

100μl

150美元

Cbl is a protein encoded by the CBL gene which is approximately 99,6 kDa. Cbl is localised to the cytoplasm and cell membrane. It is involved in negative regulation of FGFR1 signalling, signalling by EGFR in cancer and the T cell receptor signalling pathway. It is an adapter protein that functions as a negative regulator of many signalling pathways that are triggered by activation of cell surface receptors. It accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Cbl is expressed in blood and cells of the nervous system. Mutations in the CBL gene may result in a Noonan syndrome-like disorder. STJ92057 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Cbl protein.

人类, 小鼠, 大鼠

CBL antibody, CBL2 antibody, RNF55 antibody, E3 ubiquitin-protein ligase CBL antibody, Casitas B-lineage lymphoma proto-oncogene antibody, Proto-oncogene c-Cbl antibody, RING finger protein 55 antibody, RING-type E3 ubiquitin transferase CBL antibody, Signal transduction protein CBL antibody

Synthesized peptide derived from human Cbl around the non-phosphorylation site of Y674.

610-690氨基酸

Cytoplasm. Cell membrane. Note=Colocalizes with FGFR2 in lipid rafts at the cell membrane.

Cbl Polyclonal Antibody detects endogenous levels of Cbl protein.

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

液体PBS含50% 甘油, 0.5% BSA

0.02% 叠氮化钠

1毫克/毫升

免疫印迹, 免疫组化-p, 酶联免疫吸附测定

Store at -20°C, and avoid repeat freeze-thaw cycles.