产品简要
公司名称 :
St John's Laboratory
产品类型 :
抗体
产品名称 :
抗p63抗体
目录 :
STJ94912
规格 :
100μl
价格 :
150美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
目录代码 :
STJ94912
产品名称 :
抗p63抗体
产品类型 :
一抗
宿主物种 :
克隆性 :
多克隆
共轭 :
未共轭
抗体亚型 :
IgG
规格 :
100μl
标价 :
150美元
产品描述 :
P63 is a protein encoded by the TP63 gene which is approximately 76,8 kDa. P63 is localised to the nucleus and is involved in the regulation of transcription of cell death genes, activation of BH3-only proteins, regulation of TP53 activity and gene expression. This protein falls under the p53 family of transcription factors. p63 acts as a sequence specific DNA binding transcriptional activator or repressor. By interacting with TP73/p73 it may also be required for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. It is expressed in the skin, muscle, blood and lungs. Mutations in the TP63 gene can result in ectrodactyly and Rap-Hodgkin syndrome. STJ94912 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of p63 protein.
交叉活性 :
Human, Mouse, Rat, Monkey
别名 :
TP63 antibody, KET antibody, P63 antibody, P73H antibody, P73L antibody, TP73L antibody, Tumor protein 63 antibody, p63 antibody, Chronic ulcerative stomatitis protein antibody, CUSP antibody, Keratinocyte transcription factor KET antibody, Transformation-related protein 63 antibody, TP63 antibody, Tumor protein p73-like antibody, p73L antibody, p40 antibody, p51 antibody
免疫原 :
Synthesized peptide derived from human p63
表位 :
600-680氨基酸, C末端
定位 :
Nucleus
特异性 :
p63多克隆抗体检测内生水平p63蛋白
纯度 :
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
缓冲液 :
液体PBS含50% 甘油, 0.5% BSA
防腐剂 :
0.02% 叠氮化钠
浓度 :
1毫克/毫升
应用摘要 :
免疫印迹, 免疫组化-p, IF, 酶联免疫吸附测定
储存 :
Store at -20°C, and avoid repeat freeze-thaw cycles.
更多信息或购买 :
公司信息
St John's Laboratory
Unit 31, 35 Evelyn Street
London, SE8 5RT
info@stjohnslabs.com
www.stjohnslabs.com
44-0-207-232-2321
公司总部: 英国