产品简要
公司名称 :
St John's Laboratory
产品类型 :
抗体
产品名称 :
Anti-β-actin antibody
目录 :
STJ96930
规格 :
100μl
价格 :
150美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
5B7
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
St John's Laboratory 产品网页
图像
图像 1 :
St John's Laboratory STJ96930 图像 1
Western blot (WB) analysis of beta-actin Monoclonal Antibody.
产品信息
目录代码 :
STJ96930
产品名称 :
Anti-β-actin antibody
产品类型 :
一抗
宿主物种 :
小鼠
克隆性 :
单克隆
共轭 :
未共轭
克隆名称 :
5B7
抗体亚型 :
IgG1
规格 :
100μl
标价 :
150美元
产品描述 :
Beta actin is a protein encoded by the ACTB gene which is approximately 41,7 kDa. Beta actin is localised to the cytoplasm. It is involved in pathways such as blood-brain barrier and immune cell transmigration, regulation of actin cytoskeleton by Rho GTPases and development Slit-Robo signalling. This protein falls under the actin family. There are 3 main groups of actin isoforms in vertebrates namely, alpha, beta and gamma actins. Beta actin is a highly conserved proteins that is involved in various types of internal cell motility and are the major constituent of microfilaments. Beta actin is ubiquitously expressed in all eukaryotic cells. Mutations in the ACTB gene result in a form of juvenile-onset dystonia, which is defined by the presence of sustained involuntary muscle contraction, often leading to abnormal postures. Baraitser-Winter syndrome 1 is another disease that can occur due to mutations. This is rare developmental disorder that causes postnatal short stature and microcephaly, intellectual disability, seizures, and hearing loss. STJ96930 was developed from clone 60. The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen. This primary antibody binds endogenous beta actin.
交叉活性 :
Human, Rat, Mouse, Monkey, Dog, Chicken, Hamster, Rabbit, Insect
别名 :
ACTB antibody, Actin, cytoplasmic 1 antibody, Beta-actin antibody, Actin, cytoplasmic 1, N-terminally processed antibody
免疫原 :
合成肽
表位 :
C末端
定位 :
Cytoplasm, cytoskeleton Note=Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
特异性 :
The antibody detects endogenous β-actin protein.
纯度 :
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
缓冲液 :
液体PBS含50% 甘油, 0.5% BSA
防腐剂 :
0.02% 叠氮化钠
浓度 :
1毫克/毫升
应用摘要 :
免疫印迹, 免疫组化-p, 免疫细胞化学
储存 :
Store at -20°C, and avoid repeat freeze-thaw cycles.
更多信息或购买 :
St John's Laboratory 产品网页
公司信息
St John's Laboratory
Unit 31, 35 Evelyn Street
London, SE8 5RT
info@stjohnslabs.com
www.stjohnslabs.com
44-0-207-232-2321
公司总部: 英国