抗体

抗踝蛋白1抗体

STJ97271

100μl

150美元

多克隆

兔

nonconjugated

免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫组化-石蜡切片

抗踝蛋白1抗体

一抗

兔

多克隆

未共轭

IgG

100μl

150美元

Talin-1 is a protein encoded by the TLN1 gene which is approximately 269,2 kDa. Talin-1 is localised to the cytoplasm and cell surface. It is involved in RET signalling, integrin alphaIIb beta3 signalling, response to elevated platelet cytosolic Ca2+ and focal adhesion. It plays a significant role in the assembly of actin filaments and in spreading and migration of various cell types, including fibroblasts and osteoclasts. It co-distributes with integrins in the cell surface membrane in order to assist in the attachment of lymphocytes to other cells and attachment of adherent cells to extracellular matrices. Talin-1 is expressed in the blood, nervous system, liver, intestine and skin. Mutations in the TLN1 gene result in ovarian serous carcinoma. STJ97271 was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This polyclonal antibody detects endogenous levels of Talin-1 protein.

人类, 小鼠, 大鼠

TLN1抗体, KIAA1027抗体, TLN抗体, 踝蛋白1抗体

Synthesized peptide derived from human Talin-1.

C末端

Cell projection, ruffle membrane Cytoplasm, cytoskeleton Cell surface Cell junction, focal adhesion Note=Colocalizes with LAYN at the membrane ruffles. Localized preferentially in focal adhesions than fibrillar adhesions (By similarity).

踝蛋白1多克隆抗体检测内生水平踝蛋白1蛋白

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

液体PBS含50% 甘油, 0.5% BSA

0.02% 叠氮化钠

1毫克/毫升

免疫印迹, 免疫组化-p, 酶联免疫吸附测定, IF

Store at -20°C, and avoid repeat freeze-thaw cycles.