抗体

抗活性的胱氨酸-天冬氨酸蛋白酶3抗体

STJ97448

100μl

单克隆

小鼠

未共轭

5E1

人类, 小鼠

免疫印迹, 免疫细胞化学, 免疫组化-石蜡切片

抗活性的胱氨酸-天冬氨酸蛋白酶3抗体

一抗

小鼠

单克隆

未共轭

5E1

IgG1

100μl

Active caspase-3 is a protein encoded by the CASP3 gene which is approximately 31,6 kDa. Active caspase-3 is localised to the cytoplasm. It is involved in the TNFR1 pathway, apoptosis modulation and signalling and respiratory electron transport. This protein falls under the cysteine-aspartic acid protease family. It is a sequential activator of caspases and plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Active caspase-3 is highly expressed in lung, spleen, heart, liver and kidney. Mutations in the CASP3 gene may result in bladder urothelial carcinoma and primary effusion lymphoma. STJ97448 was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. This antibody detects endogenous active caspase-3 protein.

人类, 小鼠, 大鼠, 鸡

CASP3 antibody, CPP32 antibody, Caspase-3 antibody, CASP-3 antibody, Apopain antibody, Cysteine protease CPP32 antibody, CPP-32 antibody, Protein Yama antibody, SREBP cleavage activity 1 antibody, SCA-1 antibody, Caspase-3 subunit p17 antibody, Caspase-3 subunit p12 antibody

重组蛋白

细胞质

The antibody detects endogenous Active Caspase-3 protein.

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen.

液体PBS含50% 甘油, 0.5% BSA

0.02% 叠氮化钠

免疫印迹, 免疫组化-p, IF

Store at -20°C, and avoid repeat freeze-thaw cycles.