产品简要
公司名称 :
StressMarq Biosciences
产品类型 :
化学品
产品名称 :
阿霉素盐酸盐
目录 :
SIH-390
规格 :
10毫克
更多信息或购买 :
图像
图像 1 :
Chemical structure of Doxorubicin Hydrochloride (SIH-390), a Autophagy inducer. CAS #: 25316-40-9. Molecular Formula: C27H29NO11 . HCl. Molecular Weight: 580 g/mol.
产品信息
目录号 :
SIH-390
产品名称 :
阿霉素盐酸盐
描述 :
Autophagy inducer
研究领域(s) :
Cancer Autophagy
别称(s) :
Adriamycin
产品类型 :
Inducer
CAS登记号码 :
25316-40-9
MolecularFormula :
C27H29NO11•HCl
分子量 :
580
来源 :
Synthetic
纯度 :
>98% (TLC); NMR (Conforms)
SD备案 :
C27H30ClNO11
APtclcactv04251417282D 0 0.00000 0.00000
70 72 0 0 1 0 0 0 0 0999 V2000
3.9928 5.8936 0.0000 C 0 0 2 0 0 0 0 0 0 0 0 0
3.0867 4.3381 0.0000 C 0 0 1 0 0 0 0 0 0 0 0 0
4.9147 0.0000 0.0000 H 0 3 0 0 0 0 0 0 0 0 0 0
3.4589 6.2087 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
2.8777 5.9634 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
2.4759 5.2736 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
3.5992 3.3452 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
4.3974 3.3545 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
3.6847 7.7073 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
3.7650 8.2887 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
3.3745 8.9835 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
1.7622 9.2296 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
0.8833 8.1197 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
1.4051 6.8036 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
0.2367 7.4740 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
0.0000 6.6298 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
0.8443 6.3931 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
1.4848 2.8553 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
2.1735 3.2565 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
9.3428 3.1612 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
10.8295 5.7135 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
10.8295 4.0043 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
10.5148 6.9132 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
10.7319 7.7627 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
9.8824 7.9799 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
9.3499 3.7812 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
10.2937 5.4014 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
10.2937 4.3164 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.5901 3.4663 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
0.5405 6.9336 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
10.1986 7.4466 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
5.7528 5.8589 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
5.7528 3.8589 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
9.3499 5.9366 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.9021 2.9344 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
2.8476 10.2171 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
1.7738 10.2295 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
0.0231 8.6297 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
6.2897 7.1689 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
5.2158 2.5489 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
0.2822 2.9243 0.0000 H 0 0 0 0 0 0 0 0 0 0 0 0
3.0867 5.3797 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.9928 3.8243 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.1557 8.4034 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.5834 5.1983 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
7.5012 6.8935 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
7.5012 2.8243 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
2.0867 4.3342 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.5901 3.4702 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
0.5636 8.9334 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
5.7528 6.8589 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
5.7528 2.8589 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
0.5901 3.4624 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
4.0044 6.8935 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
9.3384 6.9366 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
5.9147 0.0000 0.0000 Cl 0 5 0 0 0 0 0 0 0 0 0 0
4.8867 5.3589 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
4.8867 4.3589 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
6.6188 5.3589 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
6.6188 4.3589 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
8.4188 5.3797 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
8.4188 4.3381 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
7.5127 5.8936 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
7.5127 3.8243 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
3.1442 7.4035 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.2955 8.9134 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.4238 8.4234 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
1.4122 7.4235 0.0000 C 0 0 0 0 0 0 0 0 0 0 0 0
2.3071 9.9133 0.0000 N 0 0 0 0 0 0 0 0 0 0 0 0
2.2724 6.9135 0.0000 O 0 0 0 0 0 0 0 0 0 0 0 0
1 54 1 6 0 0 0
54 65 1 0 0 0 0
65 70 1 0 0 0 0
68 70 1 0 0 0 0
2 49 1 6 0 0 0
35 49 1 0 0 0 0
50 67 1 0 0 0 0
38 50 1 0 0 0 0
32 51 1 0 0 0 0
39 51 1 0 0 0 0
33 52 1 0 0 0 0
40 52 1 0 0 0 0
45 48 2 0 0 0 0
29 53 1 0 0 0 0
41 53 1 0 0 0 0
46 63 2 0 0 0 0
47 64 2 0 0 0 0
34 55 1 0 0 0 0
31 55 1 0 0 0 0
66 69 1 0 0 0 0
36 69 1 0 0 0 0
37 69 1 0 0 0 0
1 42 1 0 0 0 0
1 57 1 0 0 0 0
1 4 1 0 0 0 0
2 42 1 0 0 0 0
2 43 1 0 0 0 0
2 48 1 0 0 0 0
5 42 1 0 0 0 0
6 42 1 0 0 0 0
43 58 1 0 0 0 0
7 43 1 0 0 0 0
8 43 1 0 0 0 0
57 58 2 0 0 0 0
32 57 1 0 0 0 0
33 58 1 0 0 0 0
44 65 1 0 0 0 0
9 65 1 0 0 0 0
44 66 1 0 0 0 0
10 44 1 0 0 0 0
11 44 1 0 0 0 0
66 67 1 0 0 0 0
12 66 1 0 0 0 0
67 68 1 0 0 0 0
13 67 1 0 0 0 0
30 68 1 0 0 0 0
14 68 1 0 0 0 0
32 59 2 0 0 0 0
29 48 1 0 0 0 0
33 60 2 0 0 0 0
59 60 1 0 0 0 0
59 63 1 0 0 0 0
60 64 1 0 0 0 0
15 30 1 0 0 0 0
16 30 1 0 0 0 0
17 30 1 0 0 0 0
18 29 1 0 0 0 0
19 29 1 0 0 0 0
61 63 1 0 0 0 0
62 64 1 0 0 0 0
61 62 2 0 0 0 0
34 61 1 0 0 0 0
26 62 1 0 0 0 0
27 34 2 0 0 0 0
26 28 2 0 0 0 0
20 26 1 0 0 0 0
27 28 1 0 0 0 0
21 27 1 0 0 0 0
22 28 1 0 0 0 0
23 31 1 0 0 0 0
24 31 1 0 0 0 0
25 31 1 0 0 0 0
M CHG 2 3 1 56 -1
M END
$$$$
PubChem CID :
443939
科研背景 :
Doxorubicin Hydrochloride is used in a clinical setting for the treatment of a wide range of cancers, including lymphomas, leukemias, and solid tumors of the breast, pancreas, stomach, bladder, and ovaries. This drug intercalates into DNA and therefore induces apoptosis by hindering cellular functions like replication and transcription by specifically inhibiting the binding of reverse transcriptase, RNA polymerase and topoisomerase II. Doxorubicin has some adverse effects for patients including immunosuppressive effects caused by hematologic toxicity. Doxorubicin has also been shown to induce autophagy in a species-specific manner.
规格1 :
10毫克
规格2 :
50毫克
更多信息或购买 :
公司信息
StressMarq Biosciences
PO Box 55036 CADBORO BAY
3825 Cadboro Bay Road
Victoria BC V8N 4G0
3825 Cadboro Bay Road
Victoria BC V8N 4G0
info@stressmarq.com
http://www.stressmarq.com1-250-294-9065
公司总部: 加拿大
StressMarq Biosciences Inc.是由Dr.Louwrier创建与温哥华的维多利亚，专注于热休克、细胞压力、离子通道及细胞信号研究领域，提供大量经过严格验证的抗体、蛋白及试剂盒。公司致力于提供高质量试剂以满足并超越客户期望。它也推出抗体试用项目，特别针对于新的研究领域，鼓励客户在购买之前先测试小规格试用产品。此外，公司提供采用新专利免疫组化技术的试剂盒，采用前所未有的抗体浓度进行实验。